Guide to the Human Genome
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Search of human proteins with 4502739

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502739 cyclin-dependent kinase 5, regulatory subunit 2
[Homo sapiens]
         (367 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502739 cyclin-dependent kinase 5, regulatory subunit 2 [Homo...   753   0.0  
gi|4502737 cyclin-dependent kinase 5, regulatory subunit 1 [Homo...   280   2e-75
gi|56549694 enabled homolog isoform a [Homo sapiens]                   52   8e-07
gi|39930375 enabled homolog isoform b [Homo sapiens]                   52   8e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    52   8e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     51   2e-06
gi|157168329 formin 1 [Homo sapiens]                                   50   2e-06
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]                50   3e-06
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]                50   3e-06
gi|52485606 formin-like 2 [Homo sapiens]                               50   4e-06
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    49   5e-06
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             49   7e-06
gi|148536848 carboxyl ester lipase precursor [Homo sapiens]            48   1e-05
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    48   1e-05
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     48   2e-05
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     48   2e-05
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    48   2e-05
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas...    47   2e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    47   2e-05
gi|33356148 formin-like 1 [Homo sapiens]                               47   2e-05
gi|11415052 retinoid X receptor, beta [Homo sapiens]                   46   5e-05
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]        46   5e-05
gi|148613878 acrosin precursor [Homo sapiens]                          46   5e-05
gi|112421108 capicua homolog [Homo sapiens]                            46   5e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    46   6e-05
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    46   6e-05
gi|117938310 sine oculis binding protein homolog [Homo sapiens]        46   6e-05
gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s...    45   8e-05
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa...    45   8e-05
gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens]            45   8e-05

>gi|4502739 cyclin-dependent kinase 5, regulatory subunit 2 [Homo
           sapiens]
          Length = 367

 Score =  753 bits (1943), Expect = 0.0
 Identities = 367/367 (100%), Positives = 367/367 (100%)

Query: 1   MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL 60
           MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL
Sbjct: 1   MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL 60

Query: 61  ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP 120
           ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP
Sbjct: 61  ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP 120

Query: 121 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ 180
           LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ
Sbjct: 121 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ 180

Query: 181 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY 240
           ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY
Sbjct: 181 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY 240

Query: 241 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL 300
           LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL
Sbjct: 241 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL 300

Query: 301 IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH 360
           IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH
Sbjct: 301 IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH 360

Query: 361 WTMNLDR 367
           WTMNLDR
Sbjct: 361 WTMNLDR 367


>gi|4502737 cyclin-dependent kinase 5, regulatory subunit 1 [Homo
           sapiens]
          Length = 307

 Score =  280 bits (715), Expect = 2e-75
 Identities = 170/328 (51%), Positives = 200/328 (60%), Gaps = 36/328 (10%)

Query: 1   MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL 60
           MGTVLSLSP+      R   L E+       G   +G Y A    K  K +  LKR S+ 
Sbjct: 1   MGTVLSLSPSY-----RKATLFED-------GAATVGHYTAVQNSKNAK-DKNLKRHSI- 46

Query: 61  ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP 120
           IS L WKR+VA SAKKK  SKKV P  +       +   N ENL +              
Sbjct: 47  ISVLPWKRIVAVSAKKKN-SKKVQPNSSYQNN---ITHLNNENLKKSL-----SCANLST 97

Query: 121 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ 180
            A P P  P A     PP+   + +Q  GS   K  P P            G+P+RVIVQ
Sbjct: 98  FAQPPPAQPPA-----PPASQLSGSQTGGSSSVKKAPHPAVTS-------AGTPKRVIVQ 145

Query: 181 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY 240
           AST ELLRCLG+F+CRRCYRLK LSP + V W R VDRSLLLQGWQDQ FITPAN+VF+Y
Sbjct: 146 ASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFLY 205

Query: 241 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL 300
           +LCR+ +   E+ S  ELQA  LTCLYL+YSYMGNEISYPLKPFLVE  KE FW RCL +
Sbjct: 206 MLCRDVI-SSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSV 264

Query: 301 IQRLSPQMLRLNADPHFFTQVFQDLKNE 328
           I  +S +ML++NADPH+FTQVF DLKNE
Sbjct: 265 INLMSSKMLQINADPHYFTQVFSDLKNE 292


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 26/60 (43%), Positives = 28/60 (46%)

Query: 115 GGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSP 174
           G  A P   P+P  PA A+   PP  G     P  S G  PPPPPPP P   PP P   P
Sbjct: 309 GPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 13/70 (18%)

Query: 118 AKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSG-------GGKPPPPPPPAP------Q 164
           A P +V  P       +     G  AA+QP  +        G   PPPPPP P       
Sbjct: 268 AAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQAS 327

Query: 165 VAPPVPGGSP 174
           VA P P G P
Sbjct: 328 VALPPPPGPP 337


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 26/60 (43%), Positives = 28/60 (46%)

Query: 115 GGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSP 174
           G  A P   P+P  PA A+   PP  G     P  S G  PPPPPPP P   PP P   P
Sbjct: 309 GPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 13/70 (18%)

Query: 118 AKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSG-------GGKPPPPPPPAP------Q 164
           A P +V  P       +     G  AA+QP  +        G   PPPPPP P       
Sbjct: 268 AAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQAS 327

Query: 165 VAPPVPGGSP 174
           VA P P G P
Sbjct: 328 VALPPPPGPP 337


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 54/187 (28%), Positives = 64/187 (34%), Gaps = 25/187 (13%)

Query: 2   GTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKG-----GKGESRLKR 56
           G+  S +P  +A     G  P     A PAG  AL     P  G G     G G  +   
Sbjct: 132 GSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAG 191

Query: 57  PSVL-----ISALTWKRLVAASAKK--KKGSKKVTPKPASTGPDPLVQQRNRENLLRKGR 109
           P         +AL      AA A      G   + P P    P  ++Q          G 
Sbjct: 192 PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFV-----GA 246

Query: 110 DPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPV 169
             P       P A P P  PAAA    PP+  + A  P     G P  PP  AP V PP 
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP-----GHPAGPPTAAPAVPPPA 301

Query: 170 P---GGS 173
               GGS
Sbjct: 302 AAQNGGS 308



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 7/70 (10%)

Query: 107 KGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGS----GGGKPPPPPPPA 162
           K R PP+G   +     PVP   A AA  EP   G A    P +     G  P P P P 
Sbjct: 125 KLRPPPEGSAGS---CAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG 181

Query: 163 PQVAPPVPGG 172
           P   P  P G
Sbjct: 182 PGPGPGKPAG 191



 Score = 35.4 bits (80), Expect = 0.082
 Identities = 33/120 (27%), Positives = 42/120 (35%), Gaps = 13/120 (10%)

Query: 70  VAASAKKKKGSKKVTPKPA-STGPDPLVQQRNRENLLRK----GRDPPDGGGTAKP---- 120
           V A+A    G+  V+  PA + G  P            +    GR  P GGG  +P    
Sbjct: 50  VRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPS 109

Query: 121 ---LAVPVPTVPAAAATCEPPSGGSAAAQP-PGSGGGKPPPPPPPAPQVAPPVPGGSPRR 176
                VP    P AA    PP G + +  P P +      P P PA    P  P     R
Sbjct: 110 PRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAAR 169



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 41/178 (23%), Positives = 50/178 (28%), Gaps = 36/178 (20%)

Query: 9   PASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKR 68
           PA +A        P     APP    A      PP    G   +    P           
Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP--------- 300

Query: 69  LVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTV 128
             AA+           P PA+ GP  +  Q            P  G   A P        
Sbjct: 301 --AAAQNGGSAGAAPAPAPAAGGPAGVSGQ------------PGPGAAAAAPAPGVKAES 346

Query: 129 PAAAATCEPPSGGSAAAQPPGSG-----------GGKPPPP--PPPAPQVAPPVPGGS 173
           P       PP+  + AA  P S            G  P P   PPPAP     +P G+
Sbjct: 347 PKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGA 404


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 50/179 (27%), Positives = 61/179 (34%), Gaps = 17/179 (9%)

Query: 9   PASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKR 68
           P    K R P   P + +  PP G     G   PP    G       +P         + 
Sbjct: 102 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 161

Query: 69  LVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTV 128
                  K + S+    KP    P    Q +       K + PP  GG  KP   P P  
Sbjct: 162 PPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN-KPQGPPPPGK 220

Query: 129 PAAAATCEPPSG---GSAAAQPPG-------SGGGKP--PPPPPPAPQVAPPVPGGSPR 175
           P       PP G     +A  PPG        GG +P  PPPPP  PQ  PP  G  P+
Sbjct: 221 PQG----PPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 275



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/172 (27%), Positives = 61/172 (35%), Gaps = 33/172 (19%)

Query: 15  GRRPGGLPEEKKKA--PPAGDEALGGYGAPP---VGKGGKGESRLKRPSVLISALTWKRL 69
           G +P G P   K    PP GD       +PP    G   +G ++ + P            
Sbjct: 209 GNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK------ 262

Query: 70  VAASAKKKKGSKKVTPKPAST--GPDPLVQQRNRENLLRKGRD---PPDGGGTAKPLAVP 124
                  + G+K   P P     GP P    ++R +    G+    PP GG   +P   P
Sbjct: 263 -PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN--QPQGPP 319

Query: 125 VPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRR 176
                       PP G      PP  GG KP  PPPP     PP  GGS  R
Sbjct: 320 ------------PPPGKPQG--PPPQGGNKPQGPPPPGKPQGPPPQGGSKSR 357



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 49/185 (26%), Positives = 61/185 (32%), Gaps = 38/185 (20%)

Query: 8   SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVG----KGGKGESRLKRPSVLISA 63
           SP    +G  P G  + +   PP G       G PP G    +G     + + P      
Sbjct: 237 SPPGKPQGPPPQGGNQPQGPPPPPGKPQ----GPPPQGGNKPQGPPPPGKPQGPP----- 287

Query: 64  LTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAV 123
                       K + S+    KP    P    Q +       K + PP  GG  KP   
Sbjct: 288 -------PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN-KPQGP 339

Query: 124 PVPTVPAAAATCEPPSGGS---AAAQPPGSGGGKP----------PPPPPPAPQVAPPVP 170
           P P  P       PP GGS   +A  PPG   G P          PPP    PQ     P
Sbjct: 340 PPPGKPQGP----PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395

Query: 171 GGSPR 175
            G P+
Sbjct: 396 AGQPQ 400



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 34/111 (30%), Positives = 42/111 (37%), Gaps = 18/111 (16%)

Query: 79  GSKKVTPKPAST--GPDPLVQQ-RNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATC 135
           G+K   P P     GP P   + R+  +   K + PP  GG       P P  P      
Sbjct: 86  GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--- 142

Query: 136 EPPSGGSAAAQPPGSGGGKPPPP-----------PPPAPQVAPPVPGGSPR 175
            PP GG+    PP  G  + PPP           PP  PQ  PP  G  P+
Sbjct: 143 -PPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ 192



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 26/75 (34%), Positives = 27/75 (36%), Gaps = 15/75 (20%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPG----------SGGGKPPPPPP 160
           PP GG   KP     P  P       PP GG+    PP            GG KP  PPP
Sbjct: 40  PPQGGN--KPQG---PPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 94

Query: 161 PAPQVAPPVPGGSPR 175
           P     PP  G   R
Sbjct: 95  PGKPQGPPPQGDKSR 109



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 12/62 (19%)

Query: 126 PTVPAAAATCEPPSGGSAAAQPPG----------SGGGKP--PPPPPPAPQVAPPVPGGS 173
           P++ A      PP GG+    PP            GG +P  PPPPP  PQ  PP  G  
Sbjct: 29  PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88

Query: 174 PR 175
           P+
Sbjct: 89  PQ 90



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 30/125 (24%), Positives = 45/125 (36%), Gaps = 13/125 (10%)

Query: 58  SVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGT 117
           SV + AL+  + +     +++    +   P    P    + +   +   K + PP  GG 
Sbjct: 7   SVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGN 66

Query: 118 AKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPP---------PPAPQVAPP 168
                 P P  P       PP GG+    PP  G  + PPP          PP     PP
Sbjct: 67  QPQGPPPPPGKPQGP----PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP 122

Query: 169 VPGGS 173
             GG+
Sbjct: 123 PQGGN 127



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 43/175 (24%), Positives = 58/175 (33%), Gaps = 23/175 (13%)

Query: 15  GRRPGGLPEEKKKA--PPAGDEALGGYGAP--PVGKGGKGESRLKRPSVLISALTWKRLV 70
           G +P G P   K    PP GD++      P  P G   +G ++ + P             
Sbjct: 86  GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK------- 138

Query: 71  AASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPA 130
                 + G+K   P P      P  Q  N+    R  R PP       P     P  P 
Sbjct: 139 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS---RSSRSPPGKPQGPPPQGGNQPQGP- 194

Query: 131 AAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQASTGE 185
                 PP  G     PP   GG  P  PPP  +   P P G  +    ++  G+
Sbjct: 195 ------PPPPGKPQGPPPQ--GGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGK 241



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 20/44 (45%), Positives = 22/44 (50%), Gaps = 5/44 (11%)

Query: 136 EPPS--GGSAAAQPPGSGGGKP--PPPPPPAPQVAPPVPGGSPR 175
           E PS   G+    PP  GG KP  PP PP  PQ  PP  G  P+
Sbjct: 27  ESPSLIAGNPQGAPP-QGGNKPQGPPSPPGKPQGPPPQGGNQPQ 69



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 50/184 (27%), Positives = 58/184 (31%), Gaps = 42/184 (22%)

Query: 15  GRRPGGLPEEKKKAPPAGDEALGG---YGAPPVGK--------GGKGESRLKRPSVLISA 63
           G +P G P    K  P G    GG    G PP GK        G K  S    P      
Sbjct: 250 GNQPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK---- 303

Query: 64  LTWKRLVAASAKKKKGSKKVTPKPASTGPD-PLVQQRNREN---LLRKGRDPPDGGGTAK 119
                        + G++   P P    P  P  Q  N+        K + PP  GG+  
Sbjct: 304 -------PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356

Query: 120 PLAVPVPTVPAAAATCE-------PPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGG 172
             A   P  P      E       PP  G    QP     G+P  PP P PQ      GG
Sbjct: 357 RSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP-PQ------GG 409

Query: 173 SPRR 176
            P R
Sbjct: 410 RPSR 413


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 33/94 (35%), Positives = 38/94 (40%), Gaps = 16/94 (17%)

Query: 81  KKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSG 140
           K + P PAS  P P +               P G G+  P A P+P V A      PP  
Sbjct: 643 KALPPPPASIPPPPPL---------------PSGLGSLSP-APPMPPVSAGPPLPPPPPP 686

Query: 141 GSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSP 174
                 P  +G   PPPPPP     APP PGG P
Sbjct: 687 PPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPP 720



 Score = 35.8 bits (81), Expect = 0.062
 Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 5/100 (5%)

Query: 73  SAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAA 132
           S  K   S ++ PK  +      +   N    +     P +G  + +  A+P P  PA+ 
Sbjct: 595 SESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPP--PASI 652

Query: 133 ATCEP-PSG-GSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170
               P PSG GS +  PP       PP PPP P   PP+P
Sbjct: 653 PPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPP-PPPLP 691



 Score = 28.5 bits (62), Expect = 10.0
 Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 8/54 (14%)

Query: 128 VPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPP-------PAPQVAPPVPGGSP 174
           + AA    E  +     A PP      PPPP P       PAP + PPV  G P
Sbjct: 627 IHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPM-PPVSAGPP 679


>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
          Length = 1240

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 41/120 (34%), Positives = 47/120 (39%), Gaps = 20/120 (16%)

Query: 79  GSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPD--GGGTAKPLAVPVPTVPAAAATCE 136
           GS    P P    P P V  +     L     PP   G G   P A P+P  P    +CE
Sbjct: 432 GSSAEPPPPPPPPPLPSVGAK----ALPTAPPPPPLPGLGAMAPPAPPLP--PPLPGSCE 485

Query: 137 ------PPSGGSAAAQPP-----GSGGGKPPPPPPPAP-QVAPPVPGGSPRRVIVQASTG 184
                 PP  G     PP     G G G PPPPPP  P   +PPV GG    ++ Q   G
Sbjct: 486 FLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHG 545



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 39/134 (29%), Positives = 52/134 (38%), Gaps = 35/134 (26%)

Query: 56  RPSVLISALTWKRLVAASAKKKKGSKK---VTPKPASTGPDPLVQQRNRENLLRKGRDPP 112
           RPS L+ A   K + A   + ++GS      TPKP+  G  P               +P 
Sbjct: 349 RPSPLVKA--HKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAA---------ACEPV 397

Query: 113 DGGGTAKPLAVPVPTVPAAAATCEPPSGG-----SAAAQPPGSGGGKPPPPPPPAPQVA- 166
           D   +   L V  P      A+  PP         ++A+PP      PPPPPPP P V  
Sbjct: 398 DHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPP------PPPPPPPLPSVGA 451

Query: 167 ---------PPVPG 171
                    PP+PG
Sbjct: 452 KALPTAPPPPPLPG 465



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 18/98 (18%)

Query: 92  PDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTV----PAAAATCEPPSGGSA---- 143
           P PLV+       ++   D    G + +    P P+V    PAAAA CEP     +    
Sbjct: 350 PSPLVKAHKS---VQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESIL 406

Query: 144 -AAQPPG---SGGGKPPPPPP---PAPQVAPPVPGGSP 174
             +QP          PPPPPP   P     PP P   P
Sbjct: 407 KVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPP 444


>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
          Length = 1249

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 41/120 (34%), Positives = 47/120 (39%), Gaps = 20/120 (16%)

Query: 79  GSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPD--GGGTAKPLAVPVPTVPAAAATCE 136
           GS    P P    P P V  +     L     PP   G G   P A P+P  P    +CE
Sbjct: 432 GSSAEPPPPPPPPPLPSVGAK----ALPTAPPPPPLPGLGAMAPPAPPLP--PPLPGSCE 485

Query: 137 ------PPSGGSAAAQPP-----GSGGGKPPPPPPPAP-QVAPPVPGGSPRRVIVQASTG 184
                 PP  G     PP     G G G PPPPPP  P   +PPV GG    ++ Q   G
Sbjct: 486 FLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHG 545



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 39/134 (29%), Positives = 52/134 (38%), Gaps = 35/134 (26%)

Query: 56  RPSVLISALTWKRLVAASAKKKKGSKK---VTPKPASTGPDPLVQQRNRENLLRKGRDPP 112
           RPS L+ A   K + A   + ++GS      TPKP+  G  P               +P 
Sbjct: 349 RPSPLVKA--HKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAA---------ACEPV 397

Query: 113 DGGGTAKPLAVPVPTVPAAAATCEPPSGG-----SAAAQPPGSGGGKPPPPPPPAPQVA- 166
           D   +   L V  P      A+  PP         ++A+PP      PPPPPPP P V  
Sbjct: 398 DHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPP------PPPPPPPLPSVGA 451

Query: 167 ---------PPVPG 171
                    PP+PG
Sbjct: 452 KALPTAPPPPPLPG 465



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 18/98 (18%)

Query: 92  PDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTV----PAAAATCEPPSGGSA---- 143
           P PLV+       ++   D    G + +    P P+V    PAAAA CEP     +    
Sbjct: 350 PSPLVKAHKS---VQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESIL 406

Query: 144 -AAQPPG---SGGGKPPPPPP---PAPQVAPPVPGGSP 174
             +QP          PPPPPP   P     PP P   P
Sbjct: 407 KVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPP 444


>gi|52485606 formin-like 2 [Homo sapiens]
          Length = 1092

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 24/67 (35%), Positives = 31/67 (46%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170
           P  G  ++ PL  P P +P ++ T E    G      P      PPPPPPP P   PP+P
Sbjct: 516 PTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLP 575

Query: 171 GGSPRRV 177
           G +   V
Sbjct: 576 GPAAETV 582



 Score = 35.4 bits (80), Expect = 0.082
 Identities = 22/64 (34%), Positives = 26/64 (40%), Gaps = 23/64 (35%)

Query: 120 PLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPP---------PAPQVAPPVP 170
           P+  P+P  P       PP        PP      PPPPPP         PAP +APP+P
Sbjct: 547 PVTPPMPPPPPPPPPPPPP--------PP------PPPPPPLPGPAAETVPAPPLAPPLP 592

Query: 171 GGSP 174
              P
Sbjct: 593 SAPP 596



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 31/129 (24%), Positives = 40/129 (31%), Gaps = 4/129 (3%)

Query: 40  GAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQR 99
           G   + K G G+  +  P V    L+    V A           +  P    P PL    
Sbjct: 479 GTIKIQKKGDGDIAIL-PVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSS 537

Query: 100 NRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPP 159
           +    ++ G   P       P   P P  P       PP  G AA   P      P P  
Sbjct: 538 DTPETVQNGPVTPP---MPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSA 594

Query: 160 PPAPQVAPP 168
           PP P  + P
Sbjct: 595 PPLPGTSSP 603


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 53/197 (26%), Positives = 77/197 (39%), Gaps = 47/197 (23%)

Query: 5    LSLSPASSAKGRRPGGLPEEKKKAP-PAGDEALGGYGAPPVGKGGKGESRLKRPSVLISA 63
            L+L P  S +G R GG P     AP P+   + GG G    G   +     + P    SA
Sbjct: 1039 LALGPQPSLRGWRGGG-PSPTPGAPSPSHHGSAGGGGGSSQGPALR---YFQLPPRAASA 1094

Query: 64   LTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKG--------------- 108
              +  + A S + +KG              PLV+Q   E   +KG               
Sbjct: 1095 AMY--VPARSGRGRKG--------------PLVKQTKVEGEPQKGGGLPPAPSPTSPASP 1138

Query: 109  RDPPDGGGTAKPLAVPVPTV----PAAAATCEPPSGGSAAAQPP-------GSGGGKPPP 157
            + PP     ++  ++P+PT+    P+ +++     G S  A+PP       G GGG   P
Sbjct: 1139 QPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSP 1198

Query: 158  PPPPAPQVAPPVPGGSP 174
             P PA    PP P   P
Sbjct: 1199 SPAPAMSPVPPSPSPVP 1215



 Score = 35.8 bits (81), Expect = 0.062
 Identities = 42/139 (30%), Positives = 50/139 (35%), Gaps = 20/139 (14%)

Query: 34   EALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTPKPAS-TGP 92
            +A GG   P    G     +L  PS L       R + AS   + G       P + T P
Sbjct: 1735 QAFGGSSTP----GPPYPPQLMTPSKLRG-----RALGASGGLRPGPSGGLRDPVTPTSP 1785

Query: 93   DPLVQQRNRENLL--RKGRDPPDGGGTAKPLAVP--VPTVPAAAATCEPPSGGSAAAQPP 148
               V     + LL  R    PP  G    P+AV   VP VP   A+  P          P
Sbjct: 1786 TVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRK------LLP 1839

Query: 149  GSGGGKPPPPPPPAPQVAP 167
               G  PPPPP P P   P
Sbjct: 1840 WEEGPGPPPPPLPGPLAQP 1858



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 23/69 (33%), Positives = 26/69 (37%), Gaps = 16/69 (23%)

Query: 122  AVPVPTVPAAAATCEPPSGGSAAAQ---------------PPGSGGGKPP-PPPPPAPQV 165
            A P+P VP  A    PP+  S A+                    G   PP PP P AP  
Sbjct: 1599 ATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAP 1658

Query: 166  APPVPGGSP 174
            A P PG  P
Sbjct: 1659 AAPQPGPDP 1667



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 28/97 (28%), Positives = 39/97 (40%), Gaps = 19/97 (19%)

Query: 87   PASTGPDPLVQQRNRENLLRKGRDPP-DGGGTAKPLAVPVPTVPAAAA-------TCEPP 138
            P + G  PL        LL+ G +PP    G +KP     P  P            C+P 
Sbjct: 1450 PTAPGVGPL--------LLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPR 1501

Query: 139  SGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPR 175
            +  ++   PP   G   P  PPP+P+ + P    SPR
Sbjct: 1502 APVTSGRGPPSEDG---PGVPPPSPRRSVPPSPTSPR 1535



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 1/72 (1%)

Query: 108  GRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSG-GGKPPPPPPPAPQVA 166
            G  P   GG   P+    PTV    A  +      A + PP +G  G P    P  P V 
Sbjct: 1767 GLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVP 1826

Query: 167  PPVPGGSPRRVI 178
             P     PR+++
Sbjct: 1827 LPTASSLPRKLL 1838



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 47/176 (26%), Positives = 61/176 (34%), Gaps = 45/176 (25%)

Query: 16   RRPGGLPEEKKK------APPAGDEALGGYGAPPVGKGGKGESRLKRPSVL----ISALT 65
            RR GG   E ++      +  AGDE  G  G   +G G     RL+    +     SA  
Sbjct: 1241 RREGGWQNEARRRSTLFLSTDAGDEDGGDGG---LGTGAAPGPRLRHSKSIDEGMFSAEP 1297

Query: 66   WKRLVAASAKKKKGSKKVTPKPASTG-----------PDPLVQQRNRENLLRKGRDPPDG 114
            + RL +A +    G      +    G           P PLV       L  K  DP   
Sbjct: 1298 YLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHP-----LTGKALDP--- 1349

Query: 115  GGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170
               A PL +    + A     +  S G  A QPP       P PP P  +  PP P
Sbjct: 1350 ---ASPLGL---ALAARERALKESSEGGGAPQPP-------PRPPSPRYEAPPPTP 1392



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 2/36 (5%)

Query: 142 SAAAQPPGSGGGKPPPP--PPPAPQVAPPVPGGSPR 175
           S +   PGS    PPP   PP  P   PPVP  S R
Sbjct: 909 SRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGR 944


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 35/98 (35%), Positives = 38/98 (38%), Gaps = 11/98 (11%)

Query: 85  PKPASTG----PDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPP-- 138
           P P S G    P P +   N+    R G  PP   G A P   P    P       PP  
Sbjct: 316 PPPPSRGGNQLPRPPIVGGNKG---RSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPP 372

Query: 139 --SGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSP 174
             +G S    PP  G G PP PPPP P   PP  G  P
Sbjct: 373 PATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGP 410



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 40/150 (26%), Positives = 52/150 (34%), Gaps = 29/150 (19%)

Query: 42  PPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNR 101
           PP     +G ++L RP ++                K  S  + P P    P P       
Sbjct: 314 PPPPPPSRGGNQLPRPPIV-------------GGNKGRSGPLPPVPLGIAPPPPTP---- 356

Query: 102 ENLLRKGRDPPDGGGTAKP------LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKP 155
                +G  PP  GG   P       + P+P  P  A     P        PP SG G  
Sbjct: 357 -----RGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPA 411

Query: 156 PPPPPPAPQVAPPV-PGGSPRRVIVQASTG 184
           PPP PPA   A  + PGG    ++ Q   G
Sbjct: 412 PPPLPPALVPAGGLAPGGGRGALLDQIRQG 441


>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
          Length = 756

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 27/67 (40%), Positives = 31/67 (46%), Gaps = 7/67 (10%)

Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163
           PP G   A P+       A PVP    + A   PP+G S A   P +G   PPP PP   
Sbjct: 630 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGD 689

Query: 164 QVAPPVP 170
             APPVP
Sbjct: 690 SGAPPVP 696



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 26/67 (38%), Positives = 30/67 (44%), Gaps = 7/67 (10%)

Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163
           PP G   A P+       A PVP    + A   PP+G S A   P +G    PP PP   
Sbjct: 586 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 645

Query: 164 QVAPPVP 170
             APPVP
Sbjct: 646 SGAPPVP 652



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 26/67 (38%), Positives = 30/67 (44%), Gaps = 7/67 (10%)

Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163
           PP G   A P+       A PVP    + A   PP+G S A   P +G    PP PP   
Sbjct: 597 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 656

Query: 164 QVAPPVP 170
             APPVP
Sbjct: 657 SGAPPVP 663



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 26/67 (38%), Positives = 30/67 (44%), Gaps = 7/67 (10%)

Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163
           PP G   A P+       A PVP    + A   PP+G S A   P +G    PP PP   
Sbjct: 608 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 667

Query: 164 QVAPPVP 170
             APPVP
Sbjct: 668 SGAPPVP 674



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 22/49 (44%), Positives = 25/49 (51%)

Query: 122 AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170
           A PVP    + AT  PP+G S  A  P +G    PP PP     APPVP
Sbjct: 560 ATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVP 608



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 7/67 (10%)

Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163
           PP G     P+       A PVP    + A   PP+G S A   P +G    PP PP   
Sbjct: 575 PPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 634

Query: 164 QVAPPVP 170
             APPVP
Sbjct: 635 SGAPPVP 641



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 4/60 (6%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170
           PP G   A     PVP    +     PP+G S A   P +G    PP PP     APPVP
Sbjct: 564 PPTGDSEA----TPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP 619



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 20/46 (43%), Positives = 24/46 (52%)

Query: 125 VPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170
           +PTV    AT  PP+G S A   P +G  +  P PP     APPVP
Sbjct: 552 LPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVP 597



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 7/66 (10%)

Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163
           PP G   A P+       A PVP    + A   PP+G +     P +G    PP PP   
Sbjct: 641 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGD 700

Query: 164 QVAPPV 169
             APPV
Sbjct: 701 SGAPPV 706



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 28/78 (35%), Positives = 30/78 (38%), Gaps = 18/78 (23%)

Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQ-PPGSGGGKPP------ 156
           PP G   A P+       A PVP    A     PP+G S A   PP    G PP      
Sbjct: 652 PPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGD 711

Query: 157 ----PPPPPAPQVAPPVP 170
               P PP     APPVP
Sbjct: 712 SETAPVPPTGDSGAPPVP 729



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 22/60 (36%), Positives = 25/60 (41%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170
           PP    T    A PVP    + A    P+G S  A  P +G    PP PP     A PVP
Sbjct: 681 PPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVP 740



 Score = 35.8 bits (81), Expect = 0.062
 Identities = 38/150 (25%), Positives = 45/150 (30%), Gaps = 46/150 (30%)

Query: 29  PPAGDEAL------GGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKK 82
           PP GD         G  GAPPV   G   +    P+                    G   
Sbjct: 630 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT--------------------GDSG 669

Query: 83  VTPKPAS--TGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSG 140
             P P +   GP P+               PP G   A P+    PT  + A    P   
Sbjct: 670 APPVPPTGDAGPPPV---------------PPTGDSGAPPVP---PTGDSGAPPVTPTGD 711

Query: 141 GSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170
              A  PP    G PP PP    + AP  P
Sbjct: 712 SETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 34/110 (30%), Positives = 41/110 (37%), Gaps = 29/110 (26%)

Query: 85  PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSG---- 140
           P P ++GP P            +GR  P    +  P A P P  P+  +   PP      
Sbjct: 292 PPPHNSGPPPPPA---------RGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRM 342

Query: 141 ---------GSAAAQPP-------GSGGGKPPPPPPPAPQVAPPVPGGSP 174
                     SA + PP       G G   PPPPPPP P   PP P G P
Sbjct: 343 YPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLP 392



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 28/78 (35%), Positives = 30/78 (38%), Gaps = 12/78 (15%)

Query: 102 ENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPP 161
           +N LR+   PP       P   P            PP   S    PP  G G PPPPP  
Sbjct: 269 KNELRRQAPPPPPPSRGGPPPPP------------PPPHNSGPPPPPARGRGAPPPPPSR 316

Query: 162 APQVAPPVPGGSPRRVIV 179
           AP  APP P  S   V V
Sbjct: 317 APTAAPPPPPPSRPSVAV 334



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 30/94 (31%), Positives = 35/94 (37%), Gaps = 7/94 (7%)

Query: 85  PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144
           P P+  GP P     +       G  PP   G   P   P P+    AA   PP    + 
Sbjct: 280 PPPSRGGPPPPPPPPHNS-----GPPPPPARGRGAP--PPPPSRAPTAAPPPPPPSRPSV 332

Query: 145 AQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVI 178
           A PP       PPPPP  P  AP  P   P  V+
Sbjct: 333 AVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVL 366



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 124 PVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRV 177
           P P +P++A +  PP   S     P +    PPPPPPP P   P +P     +V
Sbjct: 346 PPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQV 399


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 5/53 (9%)

Query: 120 PLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGG 172
           P   PVP  P       P   G+    PP  G    PPPPPP P   PP+PGG
Sbjct: 568 PSRAPVPPAPPL-----PGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGG 615



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 29/70 (41%), Positives = 33/70 (47%), Gaps = 13/70 (18%)

Query: 112 PDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPP-----GSGGGKPPPPPPPA---- 162
           P+G G   P ++P  T    A    PP  GSA   PP     GS G  PPPPP P     
Sbjct: 649 PEGVGIPSPSSLPGGT----AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGM 704

Query: 163 PQVAPPVPGG 172
           P   PP+PGG
Sbjct: 705 PPPPPPLPGG 714



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 6/67 (8%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVA---- 166
           PP  G    P   P+P      +    P G +    PP  G  + PPPPPP P  A    
Sbjct: 634 PPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP 693

Query: 167 --PPVPG 171
             PP+PG
Sbjct: 694 PPPPLPG 700



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 8/68 (11%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPP-----SGGSAAAQPPGSGG-GKPPPPP-PPAP 163
           PP   G+A+ +  P P +P +A    PP       G     PP  GG G PPPPP P  P
Sbjct: 669 PPPLPGSAR-IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 727

Query: 164 QVAPPVPG 171
            + PP PG
Sbjct: 728 GIPPPPPG 735



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 5/65 (7%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS---GGSAAAQPPGSGGGKPPPPPPPAPQVAP 167
           PP  G    P   P P +P  A    PP    GG     PP   GG   PPPPP   + P
Sbjct: 683 PPLPGSAGIP--PPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPP 740

Query: 168 PVPGG 172
           P P G
Sbjct: 741 PPPFG 745



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 23/58 (39%), Positives = 26/58 (44%), Gaps = 3/58 (5%)

Query: 120 PLAVPVPTVPAAAATCEPPS--GGSAAAQPPG-SGGGKPPPPPPPAPQVAPPVPGGSP 174
           P   P P +P       PPS  GG+A + PP  SG    PPPPP    V  P P   P
Sbjct: 604 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP 661



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 10/67 (14%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVA---- 166
           PP  G +  P   P P  P       P  GG   + PP   GG    PPPP    A    
Sbjct: 590 PPAPGDSTTPPPPPPPPPPPP-----PLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP 644

Query: 167 -PPVPGG 172
            PP+P G
Sbjct: 645 PPPLPEG 651



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 23/83 (27%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS-GGSAAAQPP-----GSG--------GGKPP 156
           PP  GG    ++ P P++P   A   PP   G A   PP     G G        GG   
Sbjct: 610 PPLPGGVC--ISSP-PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAI 666

Query: 157 PPPPPAPQVA------PPVPGGS 173
           PPPPP P  A      PP+PG +
Sbjct: 667 PPPPPLPGSARIPPPPPPLPGSA 689



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 19/56 (33%)

Query: 123 VPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP-----QVAPPVPGGS 173
           +P P  P  + T  PP        PP      PPPPPPP P        P +PGG+
Sbjct: 587 IPPPPAPGDSTTPPPP--------PP------PPPPPPPLPGGVCISSPPSLPGGT 628



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 5/70 (7%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS--GGSAAAQPPGSGGGKPPPPPPPAPQVAPP 168
           PP  G    P   P P +P       PP   GG     PP   G  PPPP       AP 
Sbjct: 696 PPLPGEAGMP--PPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 753

Query: 169 VPGG-SPRRV 177
           +P G +P+++
Sbjct: 754 LPFGLTPKKL 763


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 5/53 (9%)

Query: 120 PLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGG 172
           P   PVP  P       P   G+    PP  G    PPPPPP P   PP+PGG
Sbjct: 577 PSRAPVPPAPPL-----PGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGG 624



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 29/70 (41%), Positives = 33/70 (47%), Gaps = 13/70 (18%)

Query: 112 PDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPP-----GSGGGKPPPPPPPA---- 162
           P+G G   P ++P  T    A    PP  GSA   PP     GS G  PPPPP P     
Sbjct: 658 PEGVGIPSPSSLPGGT----AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGM 713

Query: 163 PQVAPPVPGG 172
           P   PP+PGG
Sbjct: 714 PPPPPPLPGG 723



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 6/67 (8%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVA---- 166
           PP  G    P   P+P      +    P G +    PP  G  + PPPPPP P  A    
Sbjct: 643 PPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP 702

Query: 167 --PPVPG 171
             PP+PG
Sbjct: 703 PPPPLPG 709



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 8/68 (11%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPP-----SGGSAAAQPPGSGG-GKPPPPP-PPAP 163
           PP   G+A+ +  P P +P +A    PP       G     PP  GG G PPPPP P  P
Sbjct: 678 PPPLPGSAR-IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 736

Query: 164 QVAPPVPG 171
            + PP PG
Sbjct: 737 GIPPPPPG 744



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 5/65 (7%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS---GGSAAAQPPGSGGGKPPPPPPPAPQVAP 167
           PP  G    P   P P +P  A    PP    GG     PP   GG   PPPPP   + P
Sbjct: 692 PPLPGSAGIP--PPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPP 749

Query: 168 PVPGG 172
           P P G
Sbjct: 750 PPPFG 754



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 23/58 (39%), Positives = 26/58 (44%), Gaps = 3/58 (5%)

Query: 120 PLAVPVPTVPAAAATCEPPS--GGSAAAQPPG-SGGGKPPPPPPPAPQVAPPVPGGSP 174
           P   P P +P       PPS  GG+A + PP  SG    PPPPP    V  P P   P
Sbjct: 613 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP 670



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 10/67 (14%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVA---- 166
           PP  G +  P   P P  P       P  GG   + PP   GG    PPPP    A    
Sbjct: 599 PPAPGDSTTPPPPPPPPPPPP-----PLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP 653

Query: 167 -PPVPGG 172
            PP+P G
Sbjct: 654 PPPLPEG 660



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 23/83 (27%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS-GGSAAAQPP-----GSG--------GGKPP 156
           PP  GG    ++ P P++P   A   PP   G A   PP     G G        GG   
Sbjct: 619 PPLPGGVC--ISSP-PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAI 675

Query: 157 PPPPPAPQVA------PPVPGGS 173
           PPPPP P  A      PP+PG +
Sbjct: 676 PPPPPLPGSARIPPPPPPLPGSA 698



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 19/56 (33%)

Query: 123 VPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP-----QVAPPVPGGS 173
           +P P  P  + T  PP        PP      PPPPPPP P        P +PGG+
Sbjct: 596 IPPPPAPGDSTTPPPP--------PP------PPPPPPPLPGGVCISSPPSLPGGT 637



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 5/70 (7%)

Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS--GGSAAAQPPGSGGGKPPPPPPPAPQVAPP 168
           PP  G    P   P P +P       PP   GG     PP   G  PPPP       AP 
Sbjct: 705 PPLPGEAGMP--PPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 762

Query: 169 VPGG-SPRRV 177
           +P G +P+++
Sbjct: 763 LPFGLTPKKL 772


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 49/181 (27%), Positives = 63/181 (34%), Gaps = 23/181 (12%)

Query: 9   PASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPP---VGKGGKGESRLKRPSVLISALT 65
           P    K R P   P + +  PP G     G   PP    G   +G +R + P        
Sbjct: 81  PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKP-- 138

Query: 66  WKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPV 125
             +       K +  +    KP    P    Q +       K + PP  GG  KP   P 
Sbjct: 139 --QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK-KPQGPPP 195

Query: 126 PTVPAAAATCEPPSGGSAAAQ---------PPGSGGGKP--PPPPPPAPQVAPPVPGGSP 174
           P  P       PP G  + +          PP  GG +P  PPPPP  PQ  PP  G  P
Sbjct: 196 PGKPQGP----PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 251

Query: 175 R 175
           +
Sbjct: 252 Q 252



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 46/166 (27%), Positives = 58/166 (34%), Gaps = 29/166 (17%)

Query: 15  GRRPGGLPEEKKKA--PPAGDEALGGYGAP--PVGKGGKGESRLKRPSVLISALTWKRLV 70
           G RP G P   K    PP GD++      P  P G   +G ++ + P             
Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK------- 178

Query: 71  AASAKKKKGSKKVTPKPAST--GPDPLVQQ-RNRENLLRKGRDPPDGGGTAKPLAVPVPT 127
                 + G K   P P     GP P   + R+ ++   K + PP  GG       P P 
Sbjct: 179 PQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG 238

Query: 128 VPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGS 173
            P                 PP  GG KP  PPPP     PP  GGS
Sbjct: 239 KPQG---------------PPPQGGNKPQGPPPPGKPQGPPAQGGS 269



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 51/187 (27%), Positives = 60/187 (32%), Gaps = 33/187 (17%)

Query: 9   PASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGK-------GGKGESRLKRPSVLI 61
           P    K R P   P + +  PP G     G   PP GK       GGK       P    
Sbjct: 142 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQG-PPPPPGKPQGPPPQGGKKPQGPPPPGK-- 198

Query: 62  SALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPL 121
                 +       K + S+    KP    P    Q +       K + PP  GG  KP 
Sbjct: 199 -----PQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN-KPQ 252

Query: 122 AVPVPTVPAAAATCEPPSGGS---AAAQPPGSGGGKP----------PPPPPPAPQVAPP 168
             P P  P       P  GGS   +A  PPG   G P          PPP    PQ    
Sbjct: 253 GPPPPGKPQGP----PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 308

Query: 169 VPGGSPR 175
            P G P+
Sbjct: 309 PPAGQPQ 315



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 50/185 (27%), Positives = 58/185 (31%), Gaps = 42/185 (22%)

Query: 15  GRRPGGLPEEKKKAPPAGDEALGG---YGAPPVGK-------GGKGESRLKRPSVLISAL 64
           G +P G P    K  P G    GG    G PP GK       G K  S    P       
Sbjct: 44  GNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGK----- 96

Query: 65  TWKRLVAASAKKKKGSKKVTPKPASTGPD-PLVQQRNREN---LLRKGRDPPDGGGTAKP 120
                       + G++   P P    P  P  Q  NR        K + PP  G  ++ 
Sbjct: 97  ------PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRS 150

Query: 121 LAVPVPTVPAAAATCEPPSGGSAAAQPPG----------SGGGKPPPPPPPAPQVAPPVP 170
                P  P       PP GG+    PP            GG KP  PPPP     PP  
Sbjct: 151 -----PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ 205

Query: 171 GGSPR 175
           G   R
Sbjct: 206 GDKSR 210



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 25/80 (31%), Positives = 27/80 (33%), Gaps = 14/80 (17%)

Query: 96  VQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKP 155
           V Q    +L+      P   G  KP   P            PP G      PP  GG KP
Sbjct: 23  VSQEESPSLIAGNPQGPSPQGGNKPQGPP------------PPPGKPQG--PPPQGGNKP 68

Query: 156 PPPPPPAPQVAPPVPGGSPR 175
             PPPP     PP  G   R
Sbjct: 69  QGPPPPGKPQGPPPQGDKSR 88



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 44/170 (25%), Positives = 60/170 (35%), Gaps = 36/170 (21%)

Query: 15  GRRPGGLPEEKKKA--PPAGDEALGGYGAP--PVGKGGKGESRLKRPSVLISALTWKRLV 70
           G++P G P   K    PP GD++      P  P G   +G ++ + P             
Sbjct: 187 GKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGK------- 239

Query: 71  AASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLR----KGRDPPDGGGTAKPLAVPVP 126
                 + G+K   P P      P  Q  ++    R    K + PP   G   P   P  
Sbjct: 240 PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN-NPQGPP-- 296

Query: 127 TVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRR 176
                     PP+GG+   QP     G+P  PP P PQ      GG P R
Sbjct: 297 ----------PPAGGNPQ-QPQAPPAGQPQGPPRP-PQ------GGRPSR 328


>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
           [Homo sapiens]
          Length = 355

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 20/127 (15%)

Query: 48  GKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRK 107
           G G +R KRP +  +   +   +A+    K GS  +    ++T P P             
Sbjct: 197 GVGCARAKRPGIYTATWPYLNWIAS----KIGSNALRMIQSATPPPPTT----------- 241

Query: 108 GRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAP 167
            R PP     + PL+  +P          PP   +A  +PP S    PPPPPPP P   P
Sbjct: 242 -RPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPS----PPPPPPPPPSPLP 296

Query: 168 PVPGGSP 174
           P P   P
Sbjct: 297 PPPPPPP 303


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 48/160 (30%), Positives = 55/160 (34%), Gaps = 23/160 (14%)

Query: 19   GGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKK 78
            GGL     K  P    A      PP  KGG     L  PS   +  T     AA+    K
Sbjct: 1207 GGLATPSPKGAPTTPAA-----TPPSPKGG-----LATPSPKGAPTT----PAATPPSPK 1252

Query: 79   GSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPP 138
            G    TP P      P     +    L+ G   P   G   P  V  P+     AT  P 
Sbjct: 1253 GGP-ATPPPKGAPTPPAATPPS----LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK 1307

Query: 139  SGGSAAAQPPGSGGGKPPPPPPPA----PQVAPPVPGGSP 174
               +  A  P S  G P  PPP      P V PP P G+P
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 48/169 (28%), Positives = 54/169 (31%), Gaps = 39/169 (23%)

Query: 8    SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWK 67
            SP        P G P      PP+      G  A P  KG      +  PS         
Sbjct: 972  SPKGGPATPSPKGAPTPPAATPPSPK----GGPATPSPKGAPTPPAVTPPS--------- 1018

Query: 68   RLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPT 127
                      KGS   TP P      P     +           P G   A PL    PT
Sbjct: 1019 ---------PKGSPAATPFPKGASTPPAATPPS-----------PKGSPAATPLPKGAPT 1058

Query: 128  VPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAP--PVPGGSP 174
             PAA  T   P GG A   P   G   PP   PP+P+  P  P P G+P
Sbjct: 1059 TPAA--TLPSPKGGPAT--PSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 54/170 (31%), Positives = 56/170 (32%), Gaps = 43/170 (25%)

Query: 19   GGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKK 78
            GGL     K  P    A      PP  KGG     L  PS   +  T     A     K 
Sbjct: 1161 GGLATPPPKGAPTTPAA-----TPPSPKGG-----LATPSPKGAPTT---PAATPPSPKG 1207

Query: 79   GSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPP 138
            G    +PK A T P                  P   GG A P     PT PAA  T   P
Sbjct: 1208 GLATPSPKGAPTTP--------------AATPPSPKGGLATPSPKGAPTTPAA--TPPSP 1251

Query: 139  SGGSA-----------AAQPPGSGGGKPPPPPPPAPQ---VAPPVPGGSP 174
             GG A           AA PP   GG   PP   AP    V PP P G P
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 51/176 (28%), Positives = 57/176 (32%), Gaps = 32/176 (18%)

Query: 8    SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWK 67
            SP        P G P      PP+     GG   PP  KG         PS         
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPK---GGLATPP-HKGAPTTPAATPPS--------- 1135

Query: 68   RLVAASAKKKKGSKKVTPK-----PASTGPDP---LVQQRNRENLLRKGRDPPDG-GGTA 118
                     K G     PK     PA+T P P   L     +         PP   GG A
Sbjct: 1136 --------PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187

Query: 119  KPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSP 174
             P     PT PAA  T   P GG A   P G+       PP P   +A P P G+P
Sbjct: 1188 TPSPKGAPTTPAA--TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 36/115 (31%), Positives = 40/115 (34%), Gaps = 25/115 (21%)

Query: 69   LVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDG-------GGTAKPL 121
            L   S+  KK      PK     P P            KG   P         GG A P 
Sbjct: 911  LSMTSSSPKKARATPAPKGIPASPSP------------KGAPTPPAATPPSPKGGPATPS 958

Query: 122  AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAP--PVPGGSP 174
                PT PAA     PPS     A P   G   PP   PP+P+  P  P P G+P
Sbjct: 959  PKWAPTPPAAT----PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP 1009



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 56/170 (32%), Positives = 62/170 (36%), Gaps = 43/170 (25%)

Query: 19   GGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKK 78
            GGL     K  P    A      PP  KGG     L  PS   +  T     A     K 
Sbjct: 1184 GGLATPSPKGAPTTPAA-----TPPSPKGG-----LATPSPKGAPTT---PAATPPSPKG 1230

Query: 79   GSKKVTPK-----PASTGPDPLVQQRNRENLLRKG--RDPPDGGGTAKPLAVPVPTVPAA 131
            G    +PK     PA+T P P            KG    PP  G    P A P P++   
Sbjct: 1231 GLATPSPKGAPTTPAATPPSP------------KGGPATPPPKGAPTPPAATP-PSLKGG 1277

Query: 132  AATCEPPSGGS---AAAQPPGSGGGKPPPPPP---PAPQVA-PPVPGGSP 174
             AT  PP  G+   A   PP   GG P   PP   P P  A PP P GSP
Sbjct: 1278 LAT--PPHKGAPNPAVVTPPSPKGG-PATSPPKGAPTPPAATPPSPKGSP 1324



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 48/181 (26%), Positives = 59/181 (32%), Gaps = 45/181 (24%)

Query: 5    LSLSPASSAKGRR---PGGLPEEKKK----APPAGDEALGGYGAPPVGKGGKGESRLKRP 57
            LS++ +S  K R    P G+P          PPA          PP  KGG      K  
Sbjct: 911  LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAA--------TPPSPKGGPATPSPK-- 960

Query: 58   SVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGT 117
                    W     A+          TP P      P                P   GG 
Sbjct: 961  --------WAPTPPAATPPSPKGGPATPSPKGAPTPPAATP------------PSPKGGP 1000

Query: 118  AKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPP-PPPPAPQVAP---PVPGGS 173
            A P     PT PA      PPS   + A  P   G   PP   PP+P+ +P   P+P G+
Sbjct: 1001 ATPSPKGAPTPPAVT----PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056

Query: 174  P 174
            P
Sbjct: 1057 P 1057



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 50/177 (28%), Positives = 58/177 (32%), Gaps = 30/177 (16%)

Query: 8    SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAP----PVGKGGKGESRLKRPSVLISA 63
            +P        P   P   K +P A     G    P    P  KGG     LK      +A
Sbjct: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085

Query: 64   LTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKG--RDPPDGGGTAKPL 121
                     +    KG+      PA+T P P            KG    PP  G    P 
Sbjct: 1086 TPPSPKGGPATPSPKGAPM---PPAATPPSP------------KGGLATPPHKGAPTTPA 1130

Query: 122  AVPVPTVPAAAATCEPPSGG--SAAAQPPGSGGGKPPPPPPPA----PQVAPPVPGG 172
            A P P+     AT  PP G   + AA PP   GG   PPP       P   PP P G
Sbjct: 1131 ATP-PSPKGGLAT-PPPKGAPTTPAATPPSPKGGLATPPPK-GAPTTPAATPPSPKG 1184



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 47/170 (27%), Positives = 57/170 (33%), Gaps = 29/170 (17%)

Query: 8    SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWK 67
            SP        P G P      PP+     GG   PP  KG    + +  PS      T  
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPS---LKGGLATPP-HKGAPNPAVVTPPSPKGGPAT-- 1303

Query: 68   RLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPT 127
                      KG+   TP PA+T P P             G  PP G  T   +  P P 
Sbjct: 1304 -------SPPKGAP--TP-PAATPPSPKGSP---------GTPPPKGAPTPPAVTPPSPK 1344

Query: 128  -VPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRR 176
              P   AT     GG      P S  G  PP   P+ +  P +   SP+R
Sbjct: 1345 GTPTLPATTPSSKGGPTT---PSSKEGPTPPAATPSHKGGPAMTPPSPKR 1391



 Score = 36.2 bits (82), Expect = 0.048
 Identities = 52/203 (25%), Positives = 73/203 (35%), Gaps = 30/203 (14%)

Query: 8    SPASSAKGRRPGGLPEEKKKAP--PAGDEALGGYGAPPVGKG---GKGESRLKRPSVLIS 62
            +PA       P   P   K +P  PA      G   P   KG    KG + LK   VL++
Sbjct: 1630 TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKE--VLVA 1687

Query: 63   -ALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDP-----PDGGG 116
             A     ++ A  +K   +KK +       PDP  +  ++  L      P      D   
Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747

Query: 117  TAK----------PLAVPVP--TVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQ 164
            TAK          PLA P    + P  AA  E         +P  +     P PP   P 
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFE-----KVLPKPESASVSAAPSPPVSLPL 1802

Query: 165  VAPPVPGGSPRRVIVQASTGELL 187
               PVP   P++  + +S G +L
Sbjct: 1803 APSPVPTLPPKQQFLPSSPGLVL 1825



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 36/104 (34%), Positives = 39/104 (37%), Gaps = 19/104 (18%)

Query: 87   PASTGPDPLVQQRNRENLLRKGRDPPDGGGT-AKPLAVPVPTVPAAAATCEPPSGGSA-- 143
            PA+  P          +  +K R  P   G  A P     PT PAA  T   P GG A  
Sbjct: 900  PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAA--TPPSPKGGPATP 957

Query: 144  ---------AAQPPGSGGGKPPPPPP---PAPQVA-PPVPGGSP 174
                     AA PP   GG P  P P   P P  A PP P G P
Sbjct: 958  SPKWAPTPPAATPPSPKGG-PATPSPKGAPTPPAATPPSPKGGP 1000



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 31/94 (32%), Positives = 33/94 (35%), Gaps = 16/94 (17%)

Query: 85  PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144
           PK     P P    +    L      P     T  P  +P    P  A T  PP     A
Sbjct: 896 PKEGPATPAP----KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT--PP-----A 944

Query: 145 AQPPGSGGGKPPPPPP---PAPQVA-PPVPGGSP 174
           A PP   GG P  P P   P P  A PP P G P
Sbjct: 945 ATPPSPKGG-PATPSPKWAPTPPAATPPSPKGGP 977



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 29/111 (26%), Positives = 40/111 (36%), Gaps = 12/111 (10%)

Query: 72   ASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPP---DGGGTAKPLAVPVPTV 128
            A+   KK    + PK A   P   V    +   +   ++ P        + P AV   T 
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590

Query: 129  PAAAATCE---PPSGGSAAAQPPGSGGGKPPPPPPPAPQVAP--PVPGGSP 174
              A +  E   PP    A   P       PP   PP+P+  P  P P G+P
Sbjct: 1591 KGAPSPKELLIPP----AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637



 Score = 29.3 bits (64), Expect = 5.8
 Identities = 43/175 (24%), Positives = 57/175 (32%), Gaps = 22/175 (12%)

Query: 18   PGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKK 77
            P   P   KKAP     A  G  A P  KG      +  PS         + VA S+  K
Sbjct: 1436 PAVTPVSLKKAPATS--APKGGPATPSSKGDPTLPAVTPPSPKEPPAP--KQVATSSSPK 1491

Query: 78   KGSKKVTPKPASTGPD---------PLVQQRNRENLLRKG----RDPPDGGGTAKPLAVP 124
            K      P  A T P          P      R+ +        +  P      + L  P
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551

Query: 125  VPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIV 179
              TVP+   T   P+   A A P       PP   P   + AP     SP+ +++
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP-----SPKELLI 1601



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 31/115 (26%), Positives = 41/115 (35%), Gaps = 21/115 (18%)

Query: 73   SAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAA 132
            S+K+      VTP      P P      +E L+     PP       P     PT PA  
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSP------KELLI-----PP---AVTSPSPKEAPTPPAVT 1620

Query: 133  ATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRV---IVQASTG 184
                PPS     A P   G    PP  P + + +P  P     ++   + QAS G
Sbjct: 1621 ----PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 37/119 (31%), Positives = 47/119 (39%), Gaps = 18/119 (15%)

Query: 71  AASAKKKKGSKKVTPKPASTGPDPL---VQQRNRENLLRKGRDPPDGGGTA-KPLAVPVP 126
           A  A ++    +  P  A T P  L   V++   + L+R  R P D       P+AV  P
Sbjct: 452 AMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATP 511

Query: 127 T---VPAAAATCEPPSGGSAAAQPPGSGGGKPPPPP-----------PPAPQVAPPVPG 171
           +    P        PS   A A  P  G   PPPPP           P AP  APP+PG
Sbjct: 512 SGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPG 570



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 45/167 (26%), Positives = 55/167 (32%), Gaps = 23/167 (13%)

Query: 22  PEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKR-PSVLISALTWKRLVAASAKKKKGS 80
           P E +KAPPA                 KG  R+ R P   +S      ++  +     G 
Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSI----EILPVAVATPSGG 514

Query: 81  KKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPV---PTVPAAAATCEP 137
              TP   +  P P +              PP   G   P   P    P  P    + EP
Sbjct: 515 DAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEP 574

Query: 138 PSGGSAAAQ----------PPGSGGGKPPPPPPPAPQVAPPVPGGSP 174
           P                  PPG+ G  PPPPPPP     PP PGG P
Sbjct: 575 PPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPP-----PPPPGGPP 616


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 34/108 (31%), Positives = 43/108 (39%), Gaps = 18/108 (16%)

Query: 66  WKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRD---PPDGGGTAKPLA 122
           W    AA+A    G ++ TP+P          +  R+ +   GRD   P        P  
Sbjct: 42  WLDPAAAAAAAVAGGEQQTPEPEPG-------EAGRDGMGDSGRDSRSPDSSSPNPLPQG 94

Query: 123 VPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170
           VP P+ P       PP   S A  P   G G PPPPP P P +  P P
Sbjct: 95  VPPPSPPG------PPLPPSTA--PSLGGSGAPPPPPMPPPPLGSPFP 134



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 40/144 (27%), Positives = 52/144 (36%), Gaps = 24/144 (16%)

Query: 6   SLSPASSAKGRRPGGLPEEKKKAPPAGDE---ALGGYGAPPVGKGGKGESRLKRPSVLIS 62
           S SP SS+    P G+P      PP       +LGG GAPP             P +   
Sbjct: 80  SRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPP------------PPMPPP 127

Query: 63  ALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLA 122
            L     V +S+    G     P P  +GP    Q  +  +L         GGG+  P  
Sbjct: 128 PLGSPFPVISSSMGSPGLPPPAP-PGFSGPVSSPQINSTVSL--------PGGGSGPPED 178

Query: 123 VPVPTVPAAAATCEPPSGGSAAAQ 146
           V  P +      C PP GG  A +
Sbjct: 179 VKPPVLGVRGLHCPPPPGGPGAGK 202


>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
          Length = 380

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 38/112 (33%), Positives = 48/112 (42%), Gaps = 15/112 (13%)

Query: 87  PASTGPDPLVQQRNR-----ENLLRK-----GRDPPDGGGTAKPLAVPVPTVPAAAATCE 136
           P    P+ + QQ+ +     E++ R+     G   P  GG   P   P P  P       
Sbjct: 130 PNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPPGPPPPPGL- 188

Query: 137 PPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQASTGELLR 188
           PPSG  AAA   G+GGG  PPP PP P    P  GG+    +  A  G  LR
Sbjct: 189 PPSGVPAAAH--GAGGG--PPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLR 236



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 14/86 (16%)

Query: 113 DGGGTAKPLAVPVPTVPAAAATCEP---------PSGG-----SAAAQPPGSGGGKPPPP 158
           +GGG   P A+P  +VP   +  E          PS       S A  PP    G PPPP
Sbjct: 114 EGGGPPPPPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPP 173

Query: 159 PPPAPQVAPPVPGGSPRRVIVQASTG 184
           P P P   PP P G P   +  A+ G
Sbjct: 174 PGPPPPPGPPPPPGLPPSGVPAAAHG 199



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 27/96 (28%), Positives = 33/96 (34%), Gaps = 17/96 (17%)

Query: 85  PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144
           P P + GP P                PP   G   P  +P   VPAAA      +GG   
Sbjct: 163 PAPPAGGPPP-------------PPGPPPPPGPPPPPGLPPSGVPAAAHG----AGGGPP 205

Query: 145 AQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ 180
             PP      P      AP +A  + G   R+V  Q
Sbjct: 206 PAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSKQ 241


>gi|148613878 acrosin precursor [Homo sapiens]
          Length = 421

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 40/148 (27%), Positives = 56/148 (37%), Gaps = 22/148 (14%)

Query: 33  DEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAAS--AKKKKGSKKVTPKPAST 90
           D     Y    +   G G +R KRP +  +   +   +A+   +   +  +  TP P +T
Sbjct: 248 DSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPTT 307

Query: 91  GPDPLVQQRNRENLLRKGRDPPDGGGTA------KPLAVPVPTVPAAAATCEPPSGGSAA 144
            P P+             R P     +A      +P   P+P  P AA    PPS     
Sbjct: 308 RPPPI-------------RPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSP-PPP 353

Query: 145 AQPPGSGGGKPPPPPPPAPQVAPPVPGG 172
             PP S    PPPPPPP P     +P G
Sbjct: 354 PPPPASPLPPPPPPPPPTPSSTTKLPQG 381


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 31/88 (35%), Positives = 37/88 (42%), Gaps = 15/88 (17%)

Query: 101  RENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEP-PSGGSAAAQPPGSGG---GKPP 156
            R+ +++         G   PL VP PT  AAA    P P+GG     P    G     PP
Sbjct: 1515 RQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPP 1574

Query: 157  PPPPP-----------APQVAPPVPGGS 173
             PPPP           APQ +PP PG S
Sbjct: 1575 LPPPPESGPGQPGWEGAPQPSPPPPGPS 1602



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 28/85 (32%), Positives = 33/85 (38%), Gaps = 25/85 (29%)

Query: 120 PLAVPVPTVPAAAATCEPPSGGSAAAQPPG-SGGGK-----------------PPPPPPP 161
           P   P P   AAA +   P+       PPG S  GK                 P  PPP 
Sbjct: 840 PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899

Query: 162 APQVAP---PVPGGS----PRRVIV 179
           A  V+P   P PGGS    P +V+V
Sbjct: 900 AQSVSPVQAPPPGGSAQLLPGKVLV 924



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 41/165 (24%), Positives = 51/165 (30%), Gaps = 20/165 (12%)

Query: 28   APPAGDEALGGY-GAP-PVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTP 85
            A P G      Y G+P P       +     PS++ +  T     AA+   K      T 
Sbjct: 1085 AAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATA 1144

Query: 86   KPASTGPDPLVQQRNRENLL---RKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGS 142
             PA T P P     +    L   +  R  P      K     +P     A     P  G 
Sbjct: 1145 TPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRP--GP 1202

Query: 143  AAAQPPGSG-------------GGKPPPPPPPAPQVAPPVPGGSP 174
            A  QP   G             G   PP PPP P+   P    SP
Sbjct: 1203 APRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSP 1247



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 32/112 (28%), Positives = 40/112 (35%), Gaps = 31/112 (27%)

Query: 83  VTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPA--AAATCEPPSG 140
           + P  A + PDP VQ    +               + P+A      PA  AA   E P G
Sbjct: 40  LVPFLAPSQPDPSVQPSEAQQ------------PASHPVASNQSKEPAESAAVAHERPPG 87

Query: 141 GSAAAQP--------PGSGGGKPPPP---------PPPAPQVAPPVPGGSPR 175
           G+ +A P        P S G  PP P         PPP  +     P G PR
Sbjct: 88  GTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPR 139



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 28/77 (36%), Positives = 30/77 (38%), Gaps = 16/77 (20%)

Query: 111  PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQP----------PGSG---GGKPPP 157
            PP    T  P A   P +P  A       G    A            PG G    G+PP 
Sbjct: 1232 PPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPT 1291

Query: 158  PPPPAPQVAPPV-PGGS 173
            PP PAP  AP V PGGS
Sbjct: 1292 PPSPAP--APAVAPGGS 1306



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 7/70 (10%)

Query: 115 GGTAKPLAVPVP-----TVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPV 169
           G TA PL  P P       P+ A    P    +   + P S GG  PP P  +   APP 
Sbjct: 565 GSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP--SVIAAPPS 622

Query: 170 PGGSPRRVIV 179
            GG+  + +V
Sbjct: 623 GGGNILQTLV 632



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 5/79 (6%)

Query: 110 DPP----DGGGTAKPLAVPVP-TVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQ 164
           DPP     G G+A   +   P +  A+AAT      G+  AQ  G G    P  PPP   
Sbjct: 519 DPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGA 578

Query: 165 VAPPVPGGSPRRVIVQAST 183
             P  P  + R + +  +T
Sbjct: 579 GGPATPSKATRFLPMDPAT 597



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 2/58 (3%)

Query: 129 PAAAATCEPPSGGSAAA--QPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQASTG 184
           P A+   + P+  +A A  +PPG  G   P  PP A     P PG      +V++  G
Sbjct: 65  PVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKG 122



 Score = 28.5 bits (62), Expect = 10.0
 Identities = 27/95 (28%), Positives = 37/95 (38%), Gaps = 24/95 (25%)

Query: 112  PDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQP--------PGSGGGKPP------- 156
            P  GG+A+ L   V  VP AA +     GG+    P        P   G +PP       
Sbjct: 909  PPPGGSAQLLPGKV-LVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLT 967

Query: 157  PPP--------PPAPQVAPPVPGGSPRRVIVQAST 183
            P P        PP      P P   P++V++ +ST
Sbjct: 968  PVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSST 1002


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 27/95 (28%), Positives = 37/95 (38%), Gaps = 5/95 (5%)

Query: 85  PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144
           P+P      P   Q + + ++ +G  P  G G+A P +   P      +   P SG    
Sbjct: 91  PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPT 150

Query: 145 AQPPGSGGGKPPPPPPPAP-----QVAPPVPGGSP 174
             PP +    PP  PPP P        PP  GG P
Sbjct: 151 PTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPP 185



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 33/111 (29%), Positives = 38/111 (34%), Gaps = 12/111 (10%)

Query: 72  ASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPP----DGGGTAKPLAVPVPT 127
           AS+     +   +  P  +GP P             G  PP     G  T  P A   P 
Sbjct: 127 ASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPP 186

Query: 128 VPAAAATCEPPSGGSAAAQPPGSGG---GKPPPPPPPAPQVAPPVPGGSPR 175
            PAA      P  G    Q PG GG   GK P  P P        PGG P+
Sbjct: 187 PPAAV-----PGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPK 232



 Score = 35.4 bits (80), Expect = 0.082
 Identities = 23/80 (28%), Positives = 29/80 (36%), Gaps = 3/80 (3%)

Query: 105 LRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQ 164
           L + R P   G        P+P  P      +PP       QPP     +PPP P P  Q
Sbjct: 40  LNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPH---QPPPHPQPHQQ 96

Query: 165 VAPPVPGGSPRRVIVQASTG 184
             PP P     + +V    G
Sbjct: 97  QQPPPPPQDSSKPVVAQGPG 116



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 26/97 (26%), Positives = 33/97 (34%), Gaps = 16/97 (16%)

Query: 85  PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144
           PKP    P P  QQ+         + PP      +P     P  P      +PP     +
Sbjct: 56  PKPPIPPPPPHQQQQ---------QPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDS 106

Query: 145 AQP-------PGSGGGKPPPPPPPAPQVAPPVPGGSP 174
           ++P       P  G G  PP    AP   PP  G  P
Sbjct: 107 SKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP 143



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 28/100 (28%), Positives = 35/100 (35%), Gaps = 35/100 (35%)

Query: 85  PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144
           P P    P P   Q+ +         PP    ++KP+    P           P+ G  +
Sbjct: 82  PPPHQPPPHPQPHQQQQP--------PPPPQDSSKPVVAQGPG----------PAPGVGS 123

Query: 145 A----------------QPPGSGGGKPPPPPPPAPQVAPP 168
           A                 PPGSG G P P PPPA   APP
Sbjct: 124 APPASSSAPPATPPTSGAPPGSGPG-PTPTPPPAVTSAPP 162


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 33/95 (34%), Positives = 34/95 (35%), Gaps = 11/95 (11%)

Query: 86  KPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPV-------PTVPAAAATCEPP 138
           KP    P P   Q        K + PP  G   KP   P        P  P       PP
Sbjct: 46  KPQGPPPPPGKPQGPPPQGGNKPQGPPPPG---KPQGPPPQGDKSRSPRSPPGKPQGPPP 102

Query: 139 SGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGS 173
            GG     PP  GG KP  PPPP     PP  GGS
Sbjct: 103 QGGKPQGPPP-QGGNKPQGPPPPGKPQGPPAQGGS 136



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 28/90 (31%), Positives = 33/90 (36%), Gaps = 14/90 (15%)

Query: 96  VQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKP 155
           V Q    +L+      P   G  KP     P  P       PP GG+    PP  G  + 
Sbjct: 23  VSQEESPSLIAGNPQGPSPQGGNKPQG---PPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 79

Query: 156 PPP----------PPPAPQVAPPVPGGSPR 175
           PPP          PP  PQ  PP  GG P+
Sbjct: 80  PPPQGDKSRSPRSPPGKPQ-GPPPQGGKPQ 108



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 27/71 (38%), Positives = 31/71 (43%), Gaps = 9/71 (12%)

Query: 107 KGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKP--PPPPPPAPQ 164
           K + PP  GG  KP   P P  P       PP G  + +  P S  GKP  PPP    PQ
Sbjct: 56  KPQGPPPQGGN-KPQGPPPPGKPQGP----PPQGDKSRS--PRSPPGKPQGPPPQGGKPQ 108

Query: 165 VAPPVPGGSPR 175
             PP  G  P+
Sbjct: 109 GPPPQGGNKPQ 119



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 28/82 (34%), Positives = 31/82 (37%), Gaps = 18/82 (21%)

Query: 107 KGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGS---AAAQPPGSGGGKP-------- 155
           K + PP  GG  KP   P P  P       P  GGS   +A  PPG   G P        
Sbjct: 106 KPQGPPPQGGN-KPQGPPPPGKPQGP----PAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 160

Query: 156 --PPPPPPAPQVAPPVPGGSPR 175
             PPP    PQ     P G P+
Sbjct: 161 GPPPPAGGNPQQPQAPPAGQPQ 182



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 50/183 (27%), Positives = 55/183 (30%), Gaps = 52/183 (28%)

Query: 15  GRRPGGLPEEKKKAPPAGDEALGG---YGAPPVGK-------GGKGESRLKRPSVLISAL 64
           G +P G P    K  P G    GG    G PP GK       G K  S    P       
Sbjct: 44  GNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG------ 95

Query: 65  TWKRLVAASAKKKKGSKKVTPKPAS----TGPDPLVQQRNRENLLRKGRDPPDGGGTAKP 120
                        +G K   P P       GP P            K + PP  GG+   
Sbjct: 96  ------KPQGPPPQGGKPQGPPPQGGNKPQGPPPP----------GKPQGPPAQGGSKSQ 139

Query: 121 LAVPVPTVPAAAATCE-------PPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGS 173
            A   P  P      E       PP  G    QP     G+P  PP P PQ      GG 
Sbjct: 140 SARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP-PQ------GGR 192

Query: 174 PRR 176
           P R
Sbjct: 193 PSR 195



 Score = 29.3 bits (64), Expect = 5.8
 Identities = 35/154 (22%), Positives = 47/154 (30%), Gaps = 30/154 (19%)

Query: 15  GRRPGGLPEEKKKA--PPAGDEALGGYGAP-----PVGKGGKGESRLKRPSVLISALTWK 67
           G +P G P   K    PP GD++      P     P  +GGK +                
Sbjct: 65  GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQG--------------- 109

Query: 68  RLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPT 127
                    + G+K   P P      P  Q  ++    R     P G    +      P 
Sbjct: 110 ------PPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 163

Query: 128 VPAAAATCEP--PSGGSAAAQPPGSGGGKPPPPP 159
            PA     +P  P  G     P    GG+P  PP
Sbjct: 164 PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 197


>gi|117938310 sine oculis binding protein homolog [Homo sapiens]
          Length = 873

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 50/179 (27%), Positives = 63/179 (35%), Gaps = 17/179 (9%)

Query: 2   GTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLI 61
           G  LSL+P  +  GR        +  +PP    A G  G P V +G         P   +
Sbjct: 603 GQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQG---------PQDGV 653

Query: 62  SALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPL 121
             LT    V   A+      +          +P   +R      R G   P   G   P 
Sbjct: 654 IDLT----VGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPG 709

Query: 122 AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPP-PPPAPQVAPPVPGGSPRRVIV 179
           A   P  P AAA C     G+  A   G+   +PPP  PPP P  APP    SP    V
Sbjct: 710 A---PAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPAV 765



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 29/87 (33%), Positives = 35/87 (40%), Gaps = 12/87 (13%)

Query: 85  PKPASTGPDPLVQQRNRENLLRKGRDPPDGGG-TAKPLAVPVPTVPAAAATCEPPSGGSA 143
           P  AS    PL       N +  G  PP GG     P + P+   P  +    PPS  + 
Sbjct: 416 PHHASNPNSPL------SNPMLPGIGPPPGGPRNLGPTSSPMHR-PMLSPHIHPPSTPTM 468

Query: 144 AAQPPGSGGGKPPPPPPPAPQVAPPVP 170
              PPG      PPPPP AP  + P P
Sbjct: 469 PGNPPGL----LPPPPPGAPLPSLPFP 491



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 117 TAKPLAVPVPT-VPAAAATCEPPSGGSAAAQPPGSGG---GKPPPPPPPAPQVAPPVP 170
           TA      +PT VP +    E P+    + QPP S G   G PP  PP       PVP
Sbjct: 337 TANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVP 394


>gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo
           sapiens]
          Length = 1029

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 52/187 (27%), Positives = 72/187 (38%), Gaps = 28/187 (14%)

Query: 19  GGLPEEKKKAPPAGDEALGGYG-APPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKK 77
           G + EE        D  + G+G  PP G+  K E   +R   L+     K+      KKK
Sbjct: 6   GEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQEKEQEREEQLMED---KKRKKEDKKKK 62

Query: 78  KGSKKVTPKPASTGP--DPLVQQRNRENLLRKGRDPP-DGGGTAKPLAVPVPTVPAAAAT 134
           + ++KVT +         P + Q    + +     PP +GG  AK +AVP    P+AA  
Sbjct: 63  EATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARY 122

Query: 135 CE---PPSGGSAAAQPPGSGGGKPPPP----------PPPAPQVAPPVPGGSPRRVIVQA 181
                PP              G+PPPP          PPP        PG +P    V  
Sbjct: 123 MPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPC-----TAPGANPNNAQV-- 175

Query: 182 STGELLR 188
            TG LL+
Sbjct: 176 -TGALLQ 181


>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
            sapiens]
          Length = 2113

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 27/65 (41%), Positives = 30/65 (46%), Gaps = 8/65 (12%)

Query: 118  AKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPP------PPPAPQVAPPVPG 171
            +K L +P P  PAAA+T   P    A   PP   G  PP P      PP AP  APP P 
Sbjct: 2010 SKSLGLPHPGAPAAASTATLPQRTLAMPAPP--AGTAPPAPGPTPAEPPTAPSAAPPAPS 2067

Query: 172  GSPRR 176
              P R
Sbjct: 2068 TEPPR 2072



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 3/42 (7%)

Query: 111  PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGG 152
            P    GTA P   P P  P  A +  PP   + + +PP +GG
Sbjct: 2037 PAPPAGTAPPAPGPTPAEPPTAPSAAPP---APSTEPPRAGG 2075


>gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens]
          Length = 591

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 49/184 (26%), Positives = 63/184 (34%), Gaps = 22/184 (11%)

Query: 8   SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYG---APPVGKGGKGESRL----KRPSVL 60
           SP   A+ R+  G+PEE       G    G  G         GG G+ R     KRP   
Sbjct: 104 SPPPPARARQENGMPEEPATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSS 163

Query: 61  ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDP-LVQQRNRENLLRKGRDPPDGGGTAK 119
                  +  +   +   G    TP+PA       L   R      R   D P  G   +
Sbjct: 164 REGSGGPQESSRDKRPLSGPDVGTPQPAGLASGAKLAAGRPFNTYPRADTDHPSRGAQGE 223

Query: 120 PLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPP------------PPPPAPQVAP 167
           P  V  P  P+A     P S  S++++PP    G P P             PP     AP
Sbjct: 224 PHDV-APNGPSAGGLAIPQSS-SSSSRPPTRARGAPSPGVLGPHASEPQLAPPACTPAAP 281

Query: 168 PVPG 171
            VPG
Sbjct: 282 AVPG 285


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.135    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,386,077
Number of Sequences: 37866
Number of extensions: 1395354
Number of successful extensions: 31005
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 786
Number of HSP's successfully gapped in prelim test: 1172
Number of HSP's that attempted gapping in prelim test: 12243
Number of HSP's gapped (non-prelim): 11239
length of query: 367
length of database: 18,247,518
effective HSP length: 104
effective length of query: 263
effective length of database: 14,309,454
effective search space: 3763386402
effective search space used: 3763386402
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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