BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4502739 cyclin-dependent kinase 5, regulatory subunit 2 [Homo sapiens] (367 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4502739 cyclin-dependent kinase 5, regulatory subunit 2 [Homo... 753 0.0 gi|4502737 cyclin-dependent kinase 5, regulatory subunit 1 [Homo... 280 2e-75 gi|56549694 enabled homolog isoform a [Homo sapiens] 52 8e-07 gi|39930375 enabled homolog isoform b [Homo sapiens] 52 8e-07 gi|110832843 TBP-associated factor 4 [Homo sapiens] 52 8e-07 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 51 2e-06 gi|157168329 formin 1 [Homo sapiens] 50 2e-06 gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 50 3e-06 gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 50 3e-06 gi|52485606 formin-like 2 [Homo sapiens] 50 4e-06 gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 49 5e-06 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 49 7e-06 gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 48 1e-05 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 48 1e-05 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 48 2e-05 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 48 2e-05 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 48 2e-05 gi|169163027 PREDICTED: similar to Putative acrosin-like proteas... 47 2e-05 gi|163965366 nascent polypeptide-associated complex alpha subuni... 47 2e-05 gi|33356148 formin-like 1 [Homo sapiens] 47 2e-05 gi|11415052 retinoid X receptor, beta [Homo sapiens] 46 5e-05 gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 46 5e-05 gi|148613878 acrosin precursor [Homo sapiens] 46 5e-05 gi|112421108 capicua homolog [Homo sapiens] 46 5e-05 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 46 6e-05 gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre... 46 6e-05 gi|117938310 sine oculis binding protein homolog [Homo sapiens] 46 6e-05 gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s... 45 8e-05 gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 45 8e-05 gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens] 45 8e-05 >gi|4502739 cyclin-dependent kinase 5, regulatory subunit 2 [Homo sapiens] Length = 367 Score = 753 bits (1943), Expect = 0.0 Identities = 367/367 (100%), Positives = 367/367 (100%) Query: 1 MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL 60 MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL Sbjct: 1 MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL 60 Query: 61 ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP 120 ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP Sbjct: 61 ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP 120 Query: 121 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ 180 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ Sbjct: 121 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ 180 Query: 181 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY 240 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY Sbjct: 181 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY 240 Query: 241 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL 300 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL Sbjct: 241 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL 300 Query: 301 IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH 360 IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH Sbjct: 301 IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH 360 Query: 361 WTMNLDR 367 WTMNLDR Sbjct: 361 WTMNLDR 367 >gi|4502737 cyclin-dependent kinase 5, regulatory subunit 1 [Homo sapiens] Length = 307 Score = 280 bits (715), Expect = 2e-75 Identities = 170/328 (51%), Positives = 200/328 (60%), Gaps = 36/328 (10%) Query: 1 MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL 60 MGTVLSLSP+ R L E+ G +G Y A K K + LKR S+ Sbjct: 1 MGTVLSLSPSY-----RKATLFED-------GAATVGHYTAVQNSKNAK-DKNLKRHSI- 46 Query: 61 ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP 120 IS L WKR+VA SAKKK SKKV P + + N ENL + Sbjct: 47 ISVLPWKRIVAVSAKKKN-SKKVQPNSSYQNN---ITHLNNENLKKSL-----SCANLST 97 Query: 121 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ 180 A P P P A PP+ + +Q GS K P P G+P+RVIVQ Sbjct: 98 FAQPPPAQPPA-----PPASQLSGSQTGGSSSVKKAPHPAVTS-------AGTPKRVIVQ 145 Query: 181 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY 240 AST ELLRCLG+F+CRRCYRLK LSP + V W R VDRSLLLQGWQDQ FITPAN+VF+Y Sbjct: 146 ASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFLY 205 Query: 241 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL 300 +LCR+ + E+ S ELQA LTCLYL+YSYMGNEISYPLKPFLVE KE FW RCL + Sbjct: 206 MLCRDVI-SSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSV 264 Query: 301 IQRLSPQMLRLNADPHFFTQVFQDLKNE 328 I +S +ML++NADPH+FTQVF DLKNE Sbjct: 265 INLMSSKMLQINADPHYFTQVFSDLKNE 292 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 52.0 bits (123), Expect = 8e-07 Identities = 26/60 (43%), Positives = 28/60 (46%) Query: 115 GGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSP 174 G A P P+P PA A+ PP G P S G PPPPPPP P PP P P Sbjct: 309 GPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368 Score = 30.8 bits (68), Expect = 2.0 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 13/70 (18%) Query: 118 AKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSG-------GGKPPPPPPPAP------Q 164 A P +V P + G AA+QP + G PPPPPP P Sbjct: 268 AAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQAS 327 Query: 165 VAPPVPGGSP 174 VA P P G P Sbjct: 328 VALPPPPGPP 337 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 52.0 bits (123), Expect = 8e-07 Identities = 26/60 (43%), Positives = 28/60 (46%) Query: 115 GGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSP 174 G A P P+P PA A+ PP G P S G PPPPPPP P PP P P Sbjct: 309 GPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368 Score = 30.8 bits (68), Expect = 2.0 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 13/70 (18%) Query: 118 AKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSG-------GGKPPPPPPPAP------Q 164 A P +V P + G AA+QP + G PPPPPP P Sbjct: 268 AAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQAS 327 Query: 165 VAPPVPGGSP 174 VA P P G P Sbjct: 328 VALPPPPGPP 337 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 52.0 bits (123), Expect = 8e-07 Identities = 54/187 (28%), Positives = 64/187 (34%), Gaps = 25/187 (13%) Query: 2 GTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKG-----GKGESRLKR 56 G+ S +P +A G P A PAG AL P G G G G + Sbjct: 132 GSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAG 191 Query: 57 PSVL-----ISALTWKRLVAASAKK--KKGSKKVTPKPASTGPDPLVQQRNRENLLRKGR 109 P +AL AA A G + P P P ++Q G Sbjct: 192 PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFV-----GA 246 Query: 110 DPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPV 169 P P A P P PAAA PP+ + A P G P PP AP V PP Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP-----GHPAGPPTAAPAVPPPA 301 Query: 170 P---GGS 173 GGS Sbjct: 302 AAQNGGS 308 Score = 37.7 bits (86), Expect = 0.016 Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 7/70 (10%) Query: 107 KGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGS----GGGKPPPPPPPA 162 K R PP+G + PVP A AA EP G A P + G P P P P Sbjct: 125 KLRPPPEGSAGS---CAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG 181 Query: 163 PQVAPPVPGG 172 P P P G Sbjct: 182 PGPGPGKPAG 191 Score = 35.4 bits (80), Expect = 0.082 Identities = 33/120 (27%), Positives = 42/120 (35%), Gaps = 13/120 (10%) Query: 70 VAASAKKKKGSKKVTPKPA-STGPDPLVQQRNRENLLRK----GRDPPDGGGTAKP---- 120 V A+A G+ V+ PA + G P + GR P GGG +P Sbjct: 50 VRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPS 109 Query: 121 ---LAVPVPTVPAAAATCEPPSGGSAAAQP-PGSGGGKPPPPPPPAPQVAPPVPGGSPRR 176 VP P AA PP G + + P P + P P PA P P R Sbjct: 110 PRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAAR 169 Score = 29.6 bits (65), Expect = 4.5 Identities = 41/178 (23%), Positives = 50/178 (28%), Gaps = 36/178 (20%) Query: 9 PASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKR 68 PA +A P APP A PP G + P Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPP--------- 300 Query: 69 LVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTV 128 AA+ P PA+ GP + Q P G A P Sbjct: 301 --AAAQNGGSAGAAPAPAPAAGGPAGVSGQ------------PGPGAAAAAPAPGVKAES 346 Query: 129 PAAAATCEPPSGGSAAAQPPGSG-----------GGKPPPP--PPPAPQVAPPVPGGS 173 P PP+ + AA P S G P P PPPAP +P G+ Sbjct: 347 PKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGA 404 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 50.8 bits (120), Expect = 2e-06 Identities = 50/179 (27%), Positives = 61/179 (34%), Gaps = 17/179 (9%) Query: 9 PASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKR 68 P K R P P + + PP G G PP G +P + Sbjct: 102 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 161 Query: 69 LVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTV 128 K + S+ KP P Q + K + PP GG KP P P Sbjct: 162 PPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN-KPQGPPPPGK 220 Query: 129 PAAAATCEPPSG---GSAAAQPPG-------SGGGKP--PPPPPPAPQVAPPVPGGSPR 175 P PP G +A PPG GG +P PPPPP PQ PP G P+ Sbjct: 221 PQG----PPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 275 Score = 44.3 bits (103), Expect = 2e-04 Identities = 48/172 (27%), Positives = 61/172 (35%), Gaps = 33/172 (19%) Query: 15 GRRPGGLPEEKKKA--PPAGDEALGGYGAPP---VGKGGKGESRLKRPSVLISALTWKRL 69 G +P G P K PP GD +PP G +G ++ + P Sbjct: 209 GNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK------ 262 Query: 70 VAASAKKKKGSKKVTPKPAST--GPDPLVQQRNRENLLRKGRD---PPDGGGTAKPLAVP 124 + G+K P P GP P ++R + G+ PP GG +P P Sbjct: 263 -PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN--QPQGPP 319 Query: 125 VPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRR 176 PP G PP GG KP PPPP PP GGS R Sbjct: 320 ------------PPPGKPQG--PPPQGGNKPQGPPPPGKPQGPPPQGGSKSR 357 Score = 42.0 bits (97), Expect = 9e-04 Identities = 49/185 (26%), Positives = 61/185 (32%), Gaps = 38/185 (20%) Query: 8 SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVG----KGGKGESRLKRPSVLISA 63 SP +G P G + + PP G G PP G +G + + P Sbjct: 237 SPPGKPQGPPPQGGNQPQGPPPPPGKPQ----GPPPQGGNKPQGPPPPGKPQGPP----- 287 Query: 64 LTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAV 123 K + S+ KP P Q + K + PP GG KP Sbjct: 288 -------PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN-KPQGP 339 Query: 124 PVPTVPAAAATCEPPSGGS---AAAQPPGSGGGKP----------PPPPPPAPQVAPPVP 170 P P P PP GGS +A PPG G P PPP PQ P Sbjct: 340 PPPGKPQGP----PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395 Query: 171 GGSPR 175 G P+ Sbjct: 396 AGQPQ 400 Score = 41.2 bits (95), Expect = 0.001 Identities = 34/111 (30%), Positives = 42/111 (37%), Gaps = 18/111 (16%) Query: 79 GSKKVTPKPAST--GPDPLVQQ-RNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATC 135 G+K P P GP P + R+ + K + PP GG P P P Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--- 142 Query: 136 EPPSGGSAAAQPPGSGGGKPPPP-----------PPPAPQVAPPVPGGSPR 175 PP GG+ PP G + PPP PP PQ PP G P+ Sbjct: 143 -PPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ 192 Score = 39.3 bits (90), Expect = 0.006 Identities = 26/75 (34%), Positives = 27/75 (36%), Gaps = 15/75 (20%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPG----------SGGGKPPPPPP 160 PP GG KP P P PP GG+ PP GG KP PPP Sbjct: 40 PPQGGN--KPQG---PPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 94 Query: 161 PAPQVAPPVPGGSPR 175 P PP G R Sbjct: 95 PGKPQGPPPQGDKSR 109 Score = 38.5 bits (88), Expect = 0.010 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 12/62 (19%) Query: 126 PTVPAAAATCEPPSGGSAAAQPPG----------SGGGKP--PPPPPPAPQVAPPVPGGS 173 P++ A PP GG+ PP GG +P PPPPP PQ PP G Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88 Query: 174 PR 175 P+ Sbjct: 89 PQ 90 Score = 37.0 bits (84), Expect = 0.028 Identities = 30/125 (24%), Positives = 45/125 (36%), Gaps = 13/125 (10%) Query: 58 SVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGT 117 SV + AL+ + + +++ + P P + + + K + PP GG Sbjct: 7 SVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGN 66 Query: 118 AKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPP---------PPAPQVAPP 168 P P P PP GG+ PP G + PPP PP PP Sbjct: 67 QPQGPPPPPGKPQGP----PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP 122 Query: 169 VPGGS 173 GG+ Sbjct: 123 PQGGN 127 Score = 35.0 bits (79), Expect = 0.11 Identities = 43/175 (24%), Positives = 58/175 (33%), Gaps = 23/175 (13%) Query: 15 GRRPGGLPEEKKKA--PPAGDEALGGYGAP--PVGKGGKGESRLKRPSVLISALTWKRLV 70 G +P G P K PP GD++ P P G +G ++ + P Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK------- 138 Query: 71 AASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPA 130 + G+K P P P Q N+ R R PP P P P Sbjct: 139 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS---RSSRSPPGKPQGPPPQGGNQPQGP- 194 Query: 131 AAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQASTGE 185 PP G PP GG P PPP + P P G + ++ G+ Sbjct: 195 ------PPPPGKPQGPPPQ--GGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGK 241 Score = 33.5 bits (75), Expect = 0.31 Identities = 20/44 (45%), Positives = 22/44 (50%), Gaps = 5/44 (11%) Query: 136 EPPS--GGSAAAQPPGSGGGKP--PPPPPPAPQVAPPVPGGSPR 175 E PS G+ PP GG KP PP PP PQ PP G P+ Sbjct: 27 ESPSLIAGNPQGAPP-QGGNKPQGPPSPPGKPQGPPPQGGNQPQ 69 Score = 31.6 bits (70), Expect = 1.2 Identities = 50/184 (27%), Positives = 58/184 (31%), Gaps = 42/184 (22%) Query: 15 GRRPGGLPEEKKKAPPAGDEALGG---YGAPPVGK--------GGKGESRLKRPSVLISA 63 G +P G P K P G GG G PP GK G K S P Sbjct: 250 GNQPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK---- 303 Query: 64 LTWKRLVAASAKKKKGSKKVTPKPASTGPD-PLVQQRNREN---LLRKGRDPPDGGGTAK 119 + G++ P P P P Q N+ K + PP GG+ Sbjct: 304 -------PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356 Query: 120 PLAVPVPTVPAAAATCE-------PPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGG 172 A P P E PP G QP G+P PP P PQ GG Sbjct: 357 RSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP-PQ------GG 409 Query: 173 SPRR 176 P R Sbjct: 410 RPSR 413 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 50.4 bits (119), Expect = 2e-06 Identities = 33/94 (35%), Positives = 38/94 (40%), Gaps = 16/94 (17%) Query: 81 KKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSG 140 K + P PAS P P + P G G+ P A P+P V A PP Sbjct: 643 KALPPPPASIPPPPPL---------------PSGLGSLSP-APPMPPVSAGPPLPPPPPP 686 Query: 141 GSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSP 174 P +G PPPPPP APP PGG P Sbjct: 687 PPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPP 720 Score = 35.8 bits (81), Expect = 0.062 Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 5/100 (5%) Query: 73 SAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAA 132 S K S ++ PK + + N + P +G + + A+P P PA+ Sbjct: 595 SESKTTRSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPP--PASI 652 Query: 133 ATCEP-PSG-GSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170 P PSG GS + PP PP PPP P PP+P Sbjct: 653 PPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPP-PPPLP 691 Score = 28.5 bits (62), Expect = 10.0 Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 8/54 (14%) Query: 128 VPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPP-------PAPQVAPPVPGGSP 174 + AA E + A PP PPPP P PAP + PPV G P Sbjct: 627 IHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPM-PPVSAGPP 679 >gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] Length = 1240 Score = 50.1 bits (118), Expect = 3e-06 Identities = 41/120 (34%), Positives = 47/120 (39%), Gaps = 20/120 (16%) Query: 79 GSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPD--GGGTAKPLAVPVPTVPAAAATCE 136 GS P P P P V + L PP G G P A P+P P +CE Sbjct: 432 GSSAEPPPPPPPPPLPSVGAK----ALPTAPPPPPLPGLGAMAPPAPPLP--PPLPGSCE 485 Query: 137 ------PPSGGSAAAQPP-----GSGGGKPPPPPPPAP-QVAPPVPGGSPRRVIVQASTG 184 PP G PP G G G PPPPPP P +PPV GG ++ Q G Sbjct: 486 FLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHG 545 Score = 41.2 bits (95), Expect = 0.001 Identities = 39/134 (29%), Positives = 52/134 (38%), Gaps = 35/134 (26%) Query: 56 RPSVLISALTWKRLVAASAKKKKGSKK---VTPKPASTGPDPLVQQRNRENLLRKGRDPP 112 RPS L+ A K + A + ++GS TPKP+ G P +P Sbjct: 349 RPSPLVKA--HKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAA---------ACEPV 397 Query: 113 DGGGTAKPLAVPVPTVPAAAATCEPPSGG-----SAAAQPPGSGGGKPPPPPPPAPQVA- 166 D + L V P A+ PP ++A+PP PPPPPPP P V Sbjct: 398 DHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPP------PPPPPPPLPSVGA 451 Query: 167 ---------PPVPG 171 PP+PG Sbjct: 452 KALPTAPPPPPLPG 465 Score = 38.1 bits (87), Expect = 0.013 Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 18/98 (18%) Query: 92 PDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTV----PAAAATCEPPSGGSA---- 143 P PLV+ ++ D G + + P P+V PAAAA CEP + Sbjct: 350 PSPLVKAHKS---VQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESIL 406 Query: 144 -AAQPPG---SGGGKPPPPPP---PAPQVAPPVPGGSP 174 +QP PPPPPP P PP P P Sbjct: 407 KVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPP 444 >gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] Length = 1249 Score = 50.1 bits (118), Expect = 3e-06 Identities = 41/120 (34%), Positives = 47/120 (39%), Gaps = 20/120 (16%) Query: 79 GSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPD--GGGTAKPLAVPVPTVPAAAATCE 136 GS P P P P V + L PP G G P A P+P P +CE Sbjct: 432 GSSAEPPPPPPPPPLPSVGAK----ALPTAPPPPPLPGLGAMAPPAPPLP--PPLPGSCE 485 Query: 137 ------PPSGGSAAAQPP-----GSGGGKPPPPPPPAP-QVAPPVPGGSPRRVIVQASTG 184 PP G PP G G G PPPPPP P +PPV GG ++ Q G Sbjct: 486 FLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHG 545 Score = 41.2 bits (95), Expect = 0.001 Identities = 39/134 (29%), Positives = 52/134 (38%), Gaps = 35/134 (26%) Query: 56 RPSVLISALTWKRLVAASAKKKKGSKK---VTPKPASTGPDPLVQQRNRENLLRKGRDPP 112 RPS L+ A K + A + ++GS TPKP+ G P +P Sbjct: 349 RPSPLVKA--HKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAA---------ACEPV 397 Query: 113 DGGGTAKPLAVPVPTVPAAAATCEPPSGG-----SAAAQPPGSGGGKPPPPPPPAPQVA- 166 D + L V P A+ PP ++A+PP PPPPPPP P V Sbjct: 398 DHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPP------PPPPPPPLPSVGA 451 Query: 167 ---------PPVPG 171 PP+PG Sbjct: 452 KALPTAPPPPPLPG 465 Score = 38.1 bits (87), Expect = 0.013 Identities = 30/98 (30%), Positives = 38/98 (38%), Gaps = 18/98 (18%) Query: 92 PDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTV----PAAAATCEPPSGGSA---- 143 P PLV+ ++ D G + + P P+V PAAAA CEP + Sbjct: 350 PSPLVKAHKS---VQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESIL 406 Query: 144 -AAQPPG---SGGGKPPPPPP---PAPQVAPPVPGGSP 174 +QP PPPPPP P PP P P Sbjct: 407 KVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPP 444 >gi|52485606 formin-like 2 [Homo sapiens] Length = 1092 Score = 49.7 bits (117), Expect = 4e-06 Identities = 24/67 (35%), Positives = 31/67 (46%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170 P G ++ PL P P +P ++ T E G P PPPPPPP P PP+P Sbjct: 516 PTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLP 575 Query: 171 GGSPRRV 177 G + V Sbjct: 576 GPAAETV 582 Score = 35.4 bits (80), Expect = 0.082 Identities = 22/64 (34%), Positives = 26/64 (40%), Gaps = 23/64 (35%) Query: 120 PLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPP---------PAPQVAPPVP 170 P+ P+P P PP PP PPPPPP PAP +APP+P Sbjct: 547 PVTPPMPPPPPPPPPPPPP--------PP------PPPPPPLPGPAAETVPAPPLAPPLP 592 Query: 171 GGSP 174 P Sbjct: 593 SAPP 596 Score = 29.6 bits (65), Expect = 4.5 Identities = 31/129 (24%), Positives = 40/129 (31%), Gaps = 4/129 (3%) Query: 40 GAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQR 99 G + K G G+ + P V L+ V A + P P PL Sbjct: 479 GTIKIQKKGDGDIAIL-PVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSS 537 Query: 100 NRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPP 159 + ++ G P P P P P PP G AA P P P Sbjct: 538 DTPETVQNGPVTPP---MPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSA 594 Query: 160 PPAPQVAPP 168 PP P + P Sbjct: 595 PPLPGTSSP 603 >gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens] Length = 2161 Score = 49.3 bits (116), Expect = 5e-06 Identities = 53/197 (26%), Positives = 77/197 (39%), Gaps = 47/197 (23%) Query: 5 LSLSPASSAKGRRPGGLPEEKKKAP-PAGDEALGGYGAPPVGKGGKGESRLKRPSVLISA 63 L+L P S +G R GG P AP P+ + GG G G + + P SA Sbjct: 1039 LALGPQPSLRGWRGGG-PSPTPGAPSPSHHGSAGGGGGSSQGPALR---YFQLPPRAASA 1094 Query: 64 LTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKG--------------- 108 + + A S + +KG PLV+Q E +KG Sbjct: 1095 AMY--VPARSGRGRKG--------------PLVKQTKVEGEPQKGGGLPPAPSPTSPASP 1138 Query: 109 RDPPDGGGTAKPLAVPVPTV----PAAAATCEPPSGGSAAAQPP-------GSGGGKPPP 157 + PP ++ ++P+PT+ P+ +++ G S A+PP G GGG P Sbjct: 1139 QPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSP 1198 Query: 158 PPPPAPQVAPPVPGGSP 174 P PA PP P P Sbjct: 1199 SPAPAMSPVPPSPSPVP 1215 Score = 35.8 bits (81), Expect = 0.062 Identities = 42/139 (30%), Positives = 50/139 (35%), Gaps = 20/139 (14%) Query: 34 EALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTPKPAS-TGP 92 +A GG P G +L PS L R + AS + G P + T P Sbjct: 1735 QAFGGSSTP----GPPYPPQLMTPSKLRG-----RALGASGGLRPGPSGGLRDPVTPTSP 1785 Query: 93 DPLVQQRNRENLL--RKGRDPPDGGGTAKPLAVP--VPTVPAAAATCEPPSGGSAAAQPP 148 V + LL R PP G P+AV VP VP A+ P P Sbjct: 1786 TVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRK------LLP 1839 Query: 149 GSGGGKPPPPPPPAPQVAP 167 G PPPPP P P P Sbjct: 1840 WEEGPGPPPPPLPGPLAQP 1858 Score = 34.3 bits (77), Expect = 0.18 Identities = 23/69 (33%), Positives = 26/69 (37%), Gaps = 16/69 (23%) Query: 122 AVPVPTVPAAAATCEPPSGGSAAAQ---------------PPGSGGGKPP-PPPPPAPQV 165 A P+P VP A PP+ S A+ G PP PP P AP Sbjct: 1599 ATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAP 1658 Query: 166 APPVPGGSP 174 A P PG P Sbjct: 1659 AAPQPGPDP 1667 Score = 33.9 bits (76), Expect = 0.24 Identities = 28/97 (28%), Positives = 39/97 (40%), Gaps = 19/97 (19%) Query: 87 PASTGPDPLVQQRNRENLLRKGRDPP-DGGGTAKPLAVPVPTVPAAAA-------TCEPP 138 P + G PL LL+ G +PP G +KP P P C+P Sbjct: 1450 PTAPGVGPL--------LLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPR 1501 Query: 139 SGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPR 175 + ++ PP G P PPP+P+ + P SPR Sbjct: 1502 APVTSGRGPPSEDG---PGVPPPSPRRSVPPSPTSPR 1535 Score = 32.3 bits (72), Expect = 0.69 Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 1/72 (1%) Query: 108 GRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSG-GGKPPPPPPPAPQVA 166 G P GG P+ PTV A + A + PP +G G P P P V Sbjct: 1767 GLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVP 1826 Query: 167 PPVPGGSPRRVI 178 P PR+++ Sbjct: 1827 LPTASSLPRKLL 1838 Score = 30.4 bits (67), Expect = 2.6 Identities = 47/176 (26%), Positives = 61/176 (34%), Gaps = 45/176 (25%) Query: 16 RRPGGLPEEKKK------APPAGDEALGGYGAPPVGKGGKGESRLKRPSVL----ISALT 65 RR GG E ++ + AGDE G G +G G RL+ + SA Sbjct: 1241 RREGGWQNEARRRSTLFLSTDAGDEDGGDGG---LGTGAAPGPRLRHSKSIDEGMFSAEP 1297 Query: 66 WKRLVAASAKKKKGSKKVTPKPASTG-----------PDPLVQQRNRENLLRKGRDPPDG 114 + RL +A + G + G P PLV L K DP Sbjct: 1298 YLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHP-----LTGKALDP--- 1349 Query: 115 GGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170 A PL + + A + S G A QPP P PP P + PP P Sbjct: 1350 ---ASPLGL---ALAARERALKESSEGGGAPQPP-------PRPPSPRYEAPPPTP 1392 Score = 29.6 bits (65), Expect = 4.5 Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 2/36 (5%) Query: 142 SAAAQPPGSGGGKPPPP--PPPAPQVAPPVPGGSPR 175 S + PGS PPP PP P PPVP S R Sbjct: 909 SRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGR 944 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 48.9 bits (115), Expect = 7e-06 Identities = 35/98 (35%), Positives = 38/98 (38%), Gaps = 11/98 (11%) Query: 85 PKPASTG----PDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPP-- 138 P P S G P P + N+ R G PP G A P P P PP Sbjct: 316 PPPPSRGGNQLPRPPIVGGNKG---RSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPP 372 Query: 139 --SGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSP 174 +G S PP G G PP PPPP P PP G P Sbjct: 373 PATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGP 410 Score = 42.4 bits (98), Expect = 7e-04 Identities = 40/150 (26%), Positives = 52/150 (34%), Gaps = 29/150 (19%) Query: 42 PPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNR 101 PP +G ++L RP ++ K S + P P P P Sbjct: 314 PPPPPPSRGGNQLPRPPIV-------------GGNKGRSGPLPPVPLGIAPPPPTP---- 356 Query: 102 ENLLRKGRDPPDGGGTAKP------LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKP 155 +G PP GG P + P+P P A P PP SG G Sbjct: 357 -----RGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPA 411 Query: 156 PPPPPPAPQVAPPV-PGGSPRRVIVQASTG 184 PPP PPA A + PGG ++ Q G Sbjct: 412 PPPLPPALVPAGGLAPGGGRGALLDQIRQG 441 >gi|148536848 carboxyl ester lipase precursor [Homo sapiens] Length = 756 Score = 48.1 bits (113), Expect = 1e-05 Identities = 27/67 (40%), Positives = 31/67 (46%), Gaps = 7/67 (10%) Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163 PP G A P+ A PVP + A PP+G S A P +G PPP PP Sbjct: 630 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGD 689 Query: 164 QVAPPVP 170 APPVP Sbjct: 690 SGAPPVP 696 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/67 (38%), Positives = 30/67 (44%), Gaps = 7/67 (10%) Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163 PP G A P+ A PVP + A PP+G S A P +G PP PP Sbjct: 586 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 645 Query: 164 QVAPPVP 170 APPVP Sbjct: 646 SGAPPVP 652 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/67 (38%), Positives = 30/67 (44%), Gaps = 7/67 (10%) Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163 PP G A P+ A PVP + A PP+G S A P +G PP PP Sbjct: 597 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 656 Query: 164 QVAPPVP 170 APPVP Sbjct: 657 SGAPPVP 663 Score = 45.1 bits (105), Expect = 1e-04 Identities = 26/67 (38%), Positives = 30/67 (44%), Gaps = 7/67 (10%) Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163 PP G A P+ A PVP + A PP+G S A P +G PP PP Sbjct: 608 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 667 Query: 164 QVAPPVP 170 APPVP Sbjct: 668 SGAPPVP 674 Score = 44.3 bits (103), Expect = 2e-04 Identities = 22/49 (44%), Positives = 25/49 (51%) Query: 122 AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170 A PVP + AT PP+G S A P +G PP PP APPVP Sbjct: 560 ATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVP 608 Score = 43.9 bits (102), Expect = 2e-04 Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 7/67 (10%) Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163 PP G P+ A PVP + A PP+G S A P +G PP PP Sbjct: 575 PPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGD 634 Query: 164 QVAPPVP 170 APPVP Sbjct: 635 SGAPPVP 641 Score = 41.6 bits (96), Expect = 0.001 Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 4/60 (6%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170 PP G A PVP + PP+G S A P +G PP PP APPVP Sbjct: 564 PPTGDSEA----TPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP 619 Score = 40.4 bits (93), Expect = 0.003 Identities = 20/46 (43%), Positives = 24/46 (52%) Query: 125 VPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170 +PTV AT PP+G S A P +G + P PP APPVP Sbjct: 552 LPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVP 597 Score = 39.3 bits (90), Expect = 0.006 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 7/66 (10%) Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP 163 PP G A P+ A PVP + A PP+G + P +G PP PP Sbjct: 641 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGD 700 Query: 164 QVAPPV 169 APPV Sbjct: 701 SGAPPV 706 Score = 38.1 bits (87), Expect = 0.013 Identities = 28/78 (35%), Positives = 30/78 (38%), Gaps = 18/78 (23%) Query: 111 PPDGGGTAKPL-------AVPVPTVPAAAATCEPPSGGSAAAQ-PPGSGGGKPP------ 156 PP G A P+ A PVP A PP+G S A PP G PP Sbjct: 652 PPTGDSGAPPVPPTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGD 711 Query: 157 ----PPPPPAPQVAPPVP 170 P PP APPVP Sbjct: 712 SETAPVPPTGDSGAPPVP 729 Score = 37.7 bits (86), Expect = 0.016 Identities = 22/60 (36%), Positives = 25/60 (41%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170 PP T A PVP + A P+G S A P +G PP PP A PVP Sbjct: 681 PPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVP 740 Score = 35.8 bits (81), Expect = 0.062 Identities = 38/150 (25%), Positives = 45/150 (30%), Gaps = 46/150 (30%) Query: 29 PPAGDEAL------GGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKK 82 PP GD G GAPPV G + P+ G Sbjct: 630 PPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPT--------------------GDSG 669 Query: 83 VTPKPAS--TGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSG 140 P P + GP P+ PP G A P+ PT + A P Sbjct: 670 APPVPPTGDAGPPPV---------------PPTGDSGAPPVP---PTGDSGAPPVTPTGD 711 Query: 141 GSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170 A PP G PP PP + AP P Sbjct: 712 SETAPVPPTGDSGAPPVPPTGDSEAAPVPP 741 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 48.1 bits (113), Expect = 1e-05 Identities = 34/110 (30%), Positives = 41/110 (37%), Gaps = 29/110 (26%) Query: 85 PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSG---- 140 P P ++GP P +GR P + P A P P P+ + PP Sbjct: 292 PPPHNSGPPPPPA---------RGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRM 342 Query: 141 ---------GSAAAQPP-------GSGGGKPPPPPPPAPQVAPPVPGGSP 174 SA + PP G G PPPPPPP P PP P G P Sbjct: 343 YPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLP 392 Score = 44.3 bits (103), Expect = 2e-04 Identities = 28/78 (35%), Positives = 30/78 (38%), Gaps = 12/78 (15%) Query: 102 ENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPP 161 +N LR+ PP P P PP S PP G G PPPPP Sbjct: 269 KNELRRQAPPPPPPSRGGPPPPP------------PPPHNSGPPPPPARGRGAPPPPPSR 316 Query: 162 APQVAPPVPGGSPRRVIV 179 AP APP P S V V Sbjct: 317 APTAAPPPPPPSRPSVAV 334 Score = 43.1 bits (100), Expect = 4e-04 Identities = 30/94 (31%), Positives = 35/94 (37%), Gaps = 7/94 (7%) Query: 85 PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144 P P+ GP P + G PP G P P P+ AA PP + Sbjct: 280 PPPSRGGPPPPPPPPHNS-----GPPPPPARGRGAP--PPPPSRAPTAAPPPPPPSRPSV 332 Query: 145 AQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVI 178 A PP PPPPP P AP P P V+ Sbjct: 333 AVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVL 366 Score = 41.6 bits (96), Expect = 0.001 Identities = 19/54 (35%), Positives = 26/54 (48%) Query: 124 PVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRV 177 P P +P++A + PP S P + PPPPPPP P P +P +V Sbjct: 346 PPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQV 399 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 47.8 bits (112), Expect = 2e-05 Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 5/53 (9%) Query: 120 PLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGG 172 P PVP P P G+ PP G PPPPPP P PP+PGG Sbjct: 568 PSRAPVPPAPPL-----PGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGG 615 Score = 44.7 bits (104), Expect = 1e-04 Identities = 29/70 (41%), Positives = 33/70 (47%), Gaps = 13/70 (18%) Query: 112 PDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPP-----GSGGGKPPPPPPPA---- 162 P+G G P ++P T A PP GSA PP GS G PPPPP P Sbjct: 649 PEGVGIPSPSSLPGGT----AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGM 704 Query: 163 PQVAPPVPGG 172 P PP+PGG Sbjct: 705 PPPPPPLPGG 714 Score = 42.0 bits (97), Expect = 9e-04 Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 6/67 (8%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVA---- 166 PP G P P+P + P G + PP G + PPPPPP P A Sbjct: 634 PPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP 693 Query: 167 --PPVPG 171 PP+PG Sbjct: 694 PPPPLPG 700 Score = 42.0 bits (97), Expect = 9e-04 Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 8/68 (11%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPP-----SGGSAAAQPPGSGG-GKPPPPP-PPAP 163 PP G+A+ + P P +P +A PP G PP GG G PPPPP P P Sbjct: 669 PPPLPGSAR-IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 727 Query: 164 QVAPPVPG 171 + PP PG Sbjct: 728 GIPPPPPG 735 Score = 40.8 bits (94), Expect = 0.002 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 5/65 (7%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS---GGSAAAQPPGSGGGKPPPPPPPAPQVAP 167 PP G P P P +P A PP GG PP GG PPPPP + P Sbjct: 683 PPLPGSAGIP--PPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPP 740 Query: 168 PVPGG 172 P P G Sbjct: 741 PPPFG 745 Score = 39.3 bits (90), Expect = 0.006 Identities = 23/58 (39%), Positives = 26/58 (44%), Gaps = 3/58 (5%) Query: 120 PLAVPVPTVPAAAATCEPPS--GGSAAAQPPG-SGGGKPPPPPPPAPQVAPPVPGGSP 174 P P P +P PPS GG+A + PP SG PPPPP V P P P Sbjct: 604 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP 661 Score = 34.7 bits (78), Expect = 0.14 Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 10/67 (14%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVA---- 166 PP G + P P P P P GG + PP GG PPPP A Sbjct: 590 PPAPGDSTTPPPPPPPPPPPP-----PLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP 644 Query: 167 -PPVPGG 172 PP+P G Sbjct: 645 PPPLPEG 651 Score = 34.7 bits (78), Expect = 0.14 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 23/83 (27%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS-GGSAAAQPP-----GSG--------GGKPP 156 PP GG ++ P P++P A PP G A PP G G GG Sbjct: 610 PPLPGGVC--ISSP-PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAI 666 Query: 157 PPPPPAPQVA------PPVPGGS 173 PPPPP P A PP+PG + Sbjct: 667 PPPPPLPGSARIPPPPPPLPGSA 689 Score = 33.9 bits (76), Expect = 0.24 Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 19/56 (33%) Query: 123 VPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP-----QVAPPVPGGS 173 +P P P + T PP PP PPPPPPP P P +PGG+ Sbjct: 587 IPPPPAPGDSTTPPPP--------PP------PPPPPPPLPGGVCISSPPSLPGGT 628 Score = 32.0 bits (71), Expect = 0.90 Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 5/70 (7%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS--GGSAAAQPPGSGGGKPPPPPPPAPQVAPP 168 PP G P P P +P PP GG PP G PPPP AP Sbjct: 696 PPLPGEAGMP--PPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 753 Query: 169 VPGG-SPRRV 177 +P G +P+++ Sbjct: 754 LPFGLTPKKL 763 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 47.8 bits (112), Expect = 2e-05 Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 5/53 (9%) Query: 120 PLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGG 172 P PVP P P G+ PP G PPPPPP P PP+PGG Sbjct: 577 PSRAPVPPAPPL-----PGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGG 624 Score = 44.7 bits (104), Expect = 1e-04 Identities = 29/70 (41%), Positives = 33/70 (47%), Gaps = 13/70 (18%) Query: 112 PDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPP-----GSGGGKPPPPPPPA---- 162 P+G G P ++P T A PP GSA PP GS G PPPPP P Sbjct: 658 PEGVGIPSPSSLPGGT----AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGM 713 Query: 163 PQVAPPVPGG 172 P PP+PGG Sbjct: 714 PPPPPPLPGG 723 Score = 42.0 bits (97), Expect = 9e-04 Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 6/67 (8%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVA---- 166 PP G P P+P + P G + PP G + PPPPPP P A Sbjct: 643 PPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPP 702 Query: 167 --PPVPG 171 PP+PG Sbjct: 703 PPPPLPG 709 Score = 42.0 bits (97), Expect = 9e-04 Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 8/68 (11%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPP-----SGGSAAAQPPGSGG-GKPPPPP-PPAP 163 PP G+A+ + P P +P +A PP G PP GG G PPPPP P P Sbjct: 678 PPPLPGSAR-IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGP 736 Query: 164 QVAPPVPG 171 + PP PG Sbjct: 737 GIPPPPPG 744 Score = 40.8 bits (94), Expect = 0.002 Identities = 25/65 (38%), Positives = 27/65 (41%), Gaps = 5/65 (7%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS---GGSAAAQPPGSGGGKPPPPPPPAPQVAP 167 PP G P P P +P A PP GG PP GG PPPPP + P Sbjct: 692 PPLPGSAGIP--PPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPP 749 Query: 168 PVPGG 172 P P G Sbjct: 750 PPPFG 754 Score = 39.3 bits (90), Expect = 0.006 Identities = 23/58 (39%), Positives = 26/58 (44%), Gaps = 3/58 (5%) Query: 120 PLAVPVPTVPAAAATCEPPS--GGSAAAQPPG-SGGGKPPPPPPPAPQVAPPVPGGSP 174 P P P +P PPS GG+A + PP SG PPPPP V P P P Sbjct: 613 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLP 670 Score = 34.7 bits (78), Expect = 0.14 Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 10/67 (14%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVA---- 166 PP G + P P P P P GG + PP GG PPPP A Sbjct: 599 PPAPGDSTTPPPPPPPPPPPP-----PLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP 653 Query: 167 -PPVPGG 172 PP+P G Sbjct: 654 PPPLPEG 660 Score = 34.7 bits (78), Expect = 0.14 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 23/83 (27%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS-GGSAAAQPP-----GSG--------GGKPP 156 PP GG ++ P P++P A PP G A PP G G GG Sbjct: 619 PPLPGGVC--ISSP-PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAI 675 Query: 157 PPPPPAPQVA------PPVPGGS 173 PPPPP P A PP+PG + Sbjct: 676 PPPPPLPGSARIPPPPPPLPGSA 698 Score = 33.9 bits (76), Expect = 0.24 Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 19/56 (33%) Query: 123 VPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAP-----QVAPPVPGGS 173 +P P P + T PP PP PPPPPPP P P +PGG+ Sbjct: 596 IPPPPAPGDSTTPPPP--------PP------PPPPPPPLPGGVCISSPPSLPGGT 637 Score = 32.0 bits (71), Expect = 0.90 Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 5/70 (7%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPS--GGSAAAQPPGSGGGKPPPPPPPAPQVAPP 168 PP G P P P +P PP GG PP G PPPP AP Sbjct: 705 PPLPGEAGMP--PPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 762 Query: 169 VPGG-SPRRV 177 +P G +P+++ Sbjct: 763 LPFGLTPKKL 772 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 47.8 bits (112), Expect = 2e-05 Identities = 49/181 (27%), Positives = 63/181 (34%), Gaps = 23/181 (12%) Query: 9 PASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPP---VGKGGKGESRLKRPSVLISALT 65 P K R P P + + PP G G PP G +G +R + P Sbjct: 81 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKP-- 138 Query: 66 WKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPV 125 + K + + KP P Q + K + PP GG KP P Sbjct: 139 --QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK-KPQGPPP 195 Query: 126 PTVPAAAATCEPPSGGSAAAQ---------PPGSGGGKP--PPPPPPAPQVAPPVPGGSP 174 P P PP G + + PP GG +P PPPPP PQ PP G P Sbjct: 196 PGKPQGP----PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 251 Query: 175 R 175 + Sbjct: 252 Q 252 Score = 45.1 bits (105), Expect = 1e-04 Identities = 46/166 (27%), Positives = 58/166 (34%), Gaps = 29/166 (17%) Query: 15 GRRPGGLPEEKKKA--PPAGDEALGGYGAP--PVGKGGKGESRLKRPSVLISALTWKRLV 70 G RP G P K PP GD++ P P G +G ++ + P Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK------- 178 Query: 71 AASAKKKKGSKKVTPKPAST--GPDPLVQQ-RNRENLLRKGRDPPDGGGTAKPLAVPVPT 127 + G K P P GP P + R+ ++ K + PP GG P P Sbjct: 179 PQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG 238 Query: 128 VPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGS 173 P PP GG KP PPPP PP GGS Sbjct: 239 KPQG---------------PPPQGGNKPQGPPPPGKPQGPPAQGGS 269 Score = 40.8 bits (94), Expect = 0.002 Identities = 51/187 (27%), Positives = 60/187 (32%), Gaps = 33/187 (17%) Query: 9 PASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGK-------GGKGESRLKRPSVLI 61 P K R P P + + PP G G PP GK GGK P Sbjct: 142 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQG-PPPPPGKPQGPPPQGGKKPQGPPPPGK-- 198 Query: 62 SALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPL 121 + K + S+ KP P Q + K + PP GG KP Sbjct: 199 -----PQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN-KPQ 252 Query: 122 AVPVPTVPAAAATCEPPSGGS---AAAQPPGSGGGKP----------PPPPPPAPQVAPP 168 P P P P GGS +A PPG G P PPP PQ Sbjct: 253 GPPPPGKPQGP----PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 308 Query: 169 VPGGSPR 175 P G P+ Sbjct: 309 PPAGQPQ 315 Score = 38.5 bits (88), Expect = 0.010 Identities = 50/185 (27%), Positives = 58/185 (31%), Gaps = 42/185 (22%) Query: 15 GRRPGGLPEEKKKAPPAGDEALGG---YGAPPVGK-------GGKGESRLKRPSVLISAL 64 G +P G P K P G GG G PP GK G K S P Sbjct: 44 GNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGK----- 96 Query: 65 TWKRLVAASAKKKKGSKKVTPKPASTGPD-PLVQQRNREN---LLRKGRDPPDGGGTAKP 120 + G++ P P P P Q NR K + PP G ++ Sbjct: 97 ------PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRS 150 Query: 121 LAVPVPTVPAAAATCEPPSGGSAAAQPPG----------SGGGKPPPPPPPAPQVAPPVP 170 P P PP GG+ PP GG KP PPPP PP Sbjct: 151 -----PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ 205 Query: 171 GGSPR 175 G R Sbjct: 206 GDKSR 210 Score = 36.6 bits (83), Expect = 0.037 Identities = 25/80 (31%), Positives = 27/80 (33%), Gaps = 14/80 (17%) Query: 96 VQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKP 155 V Q +L+ P G KP P PP G PP GG KP Sbjct: 23 VSQEESPSLIAGNPQGPSPQGGNKPQGPP------------PPPGKPQG--PPPQGGNKP 68 Query: 156 PPPPPPAPQVAPPVPGGSPR 175 PPPP PP G R Sbjct: 69 QGPPPPGKPQGPPPQGDKSR 88 Score = 31.6 bits (70), Expect = 1.2 Identities = 44/170 (25%), Positives = 60/170 (35%), Gaps = 36/170 (21%) Query: 15 GRRPGGLPEEKKKA--PPAGDEALGGYGAP--PVGKGGKGESRLKRPSVLISALTWKRLV 70 G++P G P K PP GD++ P P G +G ++ + P Sbjct: 187 GKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGK------- 239 Query: 71 AASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLR----KGRDPPDGGGTAKPLAVPVP 126 + G+K P P P Q ++ R K + PP G P P Sbjct: 240 PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN-NPQGPP-- 296 Query: 127 TVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRR 176 PP+GG+ QP G+P PP P PQ GG P R Sbjct: 297 ----------PPAGGNPQ-QPQAPPAGQPQGPPRP-PQ------GGRPSR 328 >gi|169163027 PREDICTED: similar to Putative acrosin-like protease [Homo sapiens] Length = 355 Score = 47.4 bits (111), Expect = 2e-05 Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 20/127 (15%) Query: 48 GKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRK 107 G G +R KRP + + + +A+ K GS + ++T P P Sbjct: 197 GVGCARAKRPGIYTATWPYLNWIAS----KIGSNALRMIQSATPPPPTT----------- 241 Query: 108 GRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAP 167 R PP + PL+ +P PP +A +PP S PPPPPPP P P Sbjct: 242 -RPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPS----PPPPPPPPPSPLP 296 Query: 168 PVPGGSP 174 P P P Sbjct: 297 PPPPPPP 303 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 47.4 bits (111), Expect = 2e-05 Identities = 48/160 (30%), Positives = 55/160 (34%), Gaps = 23/160 (14%) Query: 19 GGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKK 78 GGL K P A PP KGG L PS + T AA+ K Sbjct: 1207 GGLATPSPKGAPTTPAA-----TPPSPKGG-----LATPSPKGAPTT----PAATPPSPK 1252 Query: 79 GSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPP 138 G TP P P + L+ G P G P V P+ AT P Sbjct: 1253 GGP-ATPPPKGAPTPPAATPPS----LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK 1307 Query: 139 SGGSAAAQPPGSGGGKPPPPPPPA----PQVAPPVPGGSP 174 + A P S G P PPP P V PP P G+P Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347 Score = 46.2 bits (108), Expect = 5e-05 Identities = 48/169 (28%), Positives = 54/169 (31%), Gaps = 39/169 (23%) Query: 8 SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWK 67 SP P G P PP+ G A P KG + PS Sbjct: 972 SPKGGPATPSPKGAPTPPAATPPSPK----GGPATPSPKGAPTPPAVTPPS--------- 1018 Query: 68 RLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPT 127 KGS TP P P + P G A PL PT Sbjct: 1019 ---------PKGSPAATPFPKGASTPPAATPPS-----------PKGSPAATPLPKGAPT 1058 Query: 128 VPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAP--PVPGGSP 174 PAA T P GG A P G PP PP+P+ P P P G+P Sbjct: 1059 TPAA--TLPSPKGGPAT--PSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103 Score = 45.1 bits (105), Expect = 1e-04 Identities = 54/170 (31%), Positives = 56/170 (32%), Gaps = 43/170 (25%) Query: 19 GGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKK 78 GGL K P A PP KGG L PS + T A K Sbjct: 1161 GGLATPPPKGAPTTPAA-----TPPSPKGG-----LATPSPKGAPTT---PAATPPSPKG 1207 Query: 79 GSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPP 138 G +PK A T P P GG A P PT PAA T P Sbjct: 1208 GLATPSPKGAPTTP--------------AATPPSPKGGLATPSPKGAPTTPAA--TPPSP 1251 Query: 139 SGGSA-----------AAQPPGSGGGKPPPPPPPAPQ---VAPPVPGGSP 174 GG A AA PP GG PP AP V PP P G P Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301 Score = 43.5 bits (101), Expect = 3e-04 Identities = 51/176 (28%), Positives = 57/176 (32%), Gaps = 32/176 (18%) Query: 8 SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWK 67 SP P G P PP+ GG PP KG PS Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPK---GGLATPP-HKGAPTTPAATPPS--------- 1135 Query: 68 RLVAASAKKKKGSKKVTPK-----PASTGPDP---LVQQRNRENLLRKGRDPPDG-GGTA 118 K G PK PA+T P P L + PP GG A Sbjct: 1136 --------PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187 Query: 119 KPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSP 174 P PT PAA T P GG A P G+ PP P +A P P G+P Sbjct: 1188 TPSPKGAPTTPAA--TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241 Score = 42.7 bits (99), Expect = 5e-04 Identities = 36/115 (31%), Positives = 40/115 (34%), Gaps = 25/115 (21%) Query: 69 LVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDG-------GGTAKPL 121 L S+ KK PK P P KG P GG A P Sbjct: 911 LSMTSSSPKKARATPAPKGIPASPSP------------KGAPTPPAATPPSPKGGPATPS 958 Query: 122 AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAP--PVPGGSP 174 PT PAA PPS A P G PP PP+P+ P P P G+P Sbjct: 959 PKWAPTPPAAT----PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP 1009 Score = 42.0 bits (97), Expect = 9e-04 Identities = 56/170 (32%), Positives = 62/170 (36%), Gaps = 43/170 (25%) Query: 19 GGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKK 78 GGL K P A PP KGG L PS + T A K Sbjct: 1184 GGLATPSPKGAPTTPAA-----TPPSPKGG-----LATPSPKGAPTT---PAATPPSPKG 1230 Query: 79 GSKKVTPK-----PASTGPDPLVQQRNRENLLRKG--RDPPDGGGTAKPLAVPVPTVPAA 131 G +PK PA+T P P KG PP G P A P P++ Sbjct: 1231 GLATPSPKGAPTTPAATPPSP------------KGGPATPPPKGAPTPPAATP-PSLKGG 1277 Query: 132 AATCEPPSGGS---AAAQPPGSGGGKPPPPPP---PAPQVA-PPVPGGSP 174 AT PP G+ A PP GG P PP P P A PP P GSP Sbjct: 1278 LAT--PPHKGAPNPAVVTPPSPKGG-PATSPPKGAPTPPAATPPSPKGSP 1324 Score = 41.2 bits (95), Expect = 0.001 Identities = 48/181 (26%), Positives = 59/181 (32%), Gaps = 45/181 (24%) Query: 5 LSLSPASSAKGRR---PGGLPEEKKK----APPAGDEALGGYGAPPVGKGGKGESRLKRP 57 LS++ +S K R P G+P PPA PP KGG K Sbjct: 911 LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAA--------TPPSPKGGPATPSPK-- 960 Query: 58 SVLISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGT 117 W A+ TP P P P GG Sbjct: 961 --------WAPTPPAATPPSPKGGPATPSPKGAPTPPAATP------------PSPKGGP 1000 Query: 118 AKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPP-PPPPAPQVAP---PVPGGS 173 A P PT PA PPS + A P G PP PP+P+ +P P+P G+ Sbjct: 1001 ATPSPKGAPTPPAVT----PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056 Query: 174 P 174 P Sbjct: 1057 P 1057 Score = 38.1 bits (87), Expect = 0.013 Identities = 50/177 (28%), Positives = 58/177 (32%), Gaps = 30/177 (16%) Query: 8 SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAP----PVGKGGKGESRLKRPSVLISA 63 +P P P K +P A G P P KGG LK +A Sbjct: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085 Query: 64 LTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKG--RDPPDGGGTAKPL 121 + KG+ PA+T P P KG PP G P Sbjct: 1086 TPPSPKGGPATPSPKGAPM---PPAATPPSP------------KGGLATPPHKGAPTTPA 1130 Query: 122 AVPVPTVPAAAATCEPPSGG--SAAAQPPGSGGGKPPPPPPPA----PQVAPPVPGG 172 A P P+ AT PP G + AA PP GG PPP P PP P G Sbjct: 1131 ATP-PSPKGGLAT-PPPKGAPTTPAATPPSPKGGLATPPPK-GAPTTPAATPPSPKG 1184 Score = 38.1 bits (87), Expect = 0.013 Identities = 47/170 (27%), Positives = 57/170 (33%), Gaps = 29/170 (17%) Query: 8 SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWK 67 SP P G P PP+ GG PP KG + + PS T Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPS---LKGGLATPP-HKGAPNPAVVTPPSPKGGPAT-- 1303 Query: 68 RLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPT 127 KG+ TP PA+T P P G PP G T + P P Sbjct: 1304 -------SPPKGAP--TP-PAATPPSPKGSP---------GTPPPKGAPTPPAVTPPSPK 1344 Query: 128 -VPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRR 176 P AT GG P S G PP P+ + P + SP+R Sbjct: 1345 GTPTLPATTPSSKGGPTT---PSSKEGPTPPAATPSHKGGPAMTPPSPKR 1391 Score = 36.2 bits (82), Expect = 0.048 Identities = 52/203 (25%), Positives = 73/203 (35%), Gaps = 30/203 (14%) Query: 8 SPASSAKGRRPGGLPEEKKKAP--PAGDEALGGYGAPPVGKG---GKGESRLKRPSVLIS 62 +PA P P K +P PA G P KG KG + LK VL++ Sbjct: 1630 TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKE--VLVA 1687 Query: 63 -ALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDP-----PDGGG 116 A ++ A +K +KK + PDP + ++ L P D Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747 Query: 117 TAK----------PLAVPVP--TVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQ 164 TAK PLA P + P AA E +P + P PP P Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFE-----KVLPKPESASVSAAPSPPVSLPL 1802 Query: 165 VAPPVPGGSPRRVIVQASTGELL 187 PVP P++ + +S G +L Sbjct: 1803 APSPVPTLPPKQQFLPSSPGLVL 1825 Score = 34.7 bits (78), Expect = 0.14 Identities = 36/104 (34%), Positives = 39/104 (37%), Gaps = 19/104 (18%) Query: 87 PASTGPDPLVQQRNRENLLRKGRDPPDGGGT-AKPLAVPVPTVPAAAATCEPPSGGSA-- 143 PA+ P + +K R P G A P PT PAA T P GG A Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAA--TPPSPKGGPATP 957 Query: 144 ---------AAQPPGSGGGKPPPPPP---PAPQVA-PPVPGGSP 174 AA PP GG P P P P P A PP P G P Sbjct: 958 SPKWAPTPPAATPPSPKGG-PATPSPKGAPTPPAATPPSPKGGP 1000 Score = 33.5 bits (75), Expect = 0.31 Identities = 31/94 (32%), Positives = 33/94 (35%), Gaps = 16/94 (17%) Query: 85 PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144 PK P P + L P T P +P P A T PP A Sbjct: 896 PKEGPATPAP----KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT--PP-----A 944 Query: 145 AQPPGSGGGKPPPPPP---PAPQVA-PPVPGGSP 174 A PP GG P P P P P A PP P G P Sbjct: 945 ATPPSPKGG-PATPSPKWAPTPPAATPPSPKGGP 977 Score = 29.6 bits (65), Expect = 4.5 Identities = 29/111 (26%), Positives = 40/111 (36%), Gaps = 12/111 (10%) Query: 72 ASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPP---DGGGTAKPLAVPVPTV 128 A+ KK + PK A P V + + ++ P + P AV T Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590 Query: 129 PAAAATCE---PPSGGSAAAQPPGSGGGKPPPPPPPAPQVAP--PVPGGSP 174 A + E PP A P PP PP+P+ P P P G+P Sbjct: 1591 KGAPSPKELLIPP----AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637 Score = 29.3 bits (64), Expect = 5.8 Identities = 43/175 (24%), Positives = 57/175 (32%), Gaps = 22/175 (12%) Query: 18 PGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKK 77 P P KKAP A G A P KG + PS + VA S+ K Sbjct: 1436 PAVTPVSLKKAPATS--APKGGPATPSSKGDPTLPAVTPPSPKEPPAP--KQVATSSSPK 1491 Query: 78 KGSKKVTPKPASTGPD---------PLVQQRNRENLLRKG----RDPPDGGGTAKPLAVP 124 K P A T P P R+ + + P + L P Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551 Query: 125 VPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIV 179 TVP+ T P+ A A P PP P + AP SP+ +++ Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP-----SPKELLI 1601 Score = 28.9 bits (63), Expect = 7.6 Identities = 31/115 (26%), Positives = 41/115 (35%), Gaps = 21/115 (18%) Query: 73 SAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAA 132 S+K+ VTP P P +E L+ PP P PT PA Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSP------KELLI-----PP---AVTSPSPKEAPTPPAVT 1620 Query: 133 ATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRV---IVQASTG 184 PPS A P G PP P + + +P P ++ + QAS G Sbjct: 1621 ----PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 47.4 bits (111), Expect = 2e-05 Identities = 37/119 (31%), Positives = 47/119 (39%), Gaps = 18/119 (15%) Query: 71 AASAKKKKGSKKVTPKPASTGPDPL---VQQRNRENLLRKGRDPPDGGGTA-KPLAVPVP 126 A A ++ + P A T P L V++ + L+R R P D P+AV P Sbjct: 452 AMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATP 511 Query: 127 T---VPAAAATCEPPSGGSAAAQPPGSGGGKPPPPP-----------PPAPQVAPPVPG 171 + P PS A A P G PPPPP P AP APP+PG Sbjct: 512 SGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPG 570 Score = 46.2 bits (108), Expect = 5e-05 Identities = 45/167 (26%), Positives = 55/167 (32%), Gaps = 23/167 (13%) Query: 22 PEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKR-PSVLISALTWKRLVAASAKKKKGS 80 P E +KAPPA KG R+ R P +S ++ + G Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSI----EILPVAVATPSGG 514 Query: 81 KKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPV---PTVPAAAATCEP 137 TP + P P + PP G P P P P + EP Sbjct: 515 DAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEP 574 Query: 138 PSGGSAAAQ----------PPGSGGGKPPPPPPPAPQVAPPVPGGSP 174 P PPG+ G PPPPPPP PP PGG P Sbjct: 575 PPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPP-----PPPPGGPP 616 >gi|11415052 retinoid X receptor, beta [Homo sapiens] Length = 533 Score = 46.2 bits (108), Expect = 5e-05 Identities = 34/108 (31%), Positives = 43/108 (39%), Gaps = 18/108 (16%) Query: 66 WKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRD---PPDGGGTAKPLA 122 W AA+A G ++ TP+P + R+ + GRD P P Sbjct: 42 WLDPAAAAAAAVAGGEQQTPEPEPG-------EAGRDGMGDSGRDSRSPDSSSPNPLPQG 94 Query: 123 VPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVP 170 VP P+ P PP S A P G G PPPPP P P + P P Sbjct: 95 VPPPSPPG------PPLPPSTA--PSLGGSGAPPPPPMPPPPLGSPFP 134 Score = 38.1 bits (87), Expect = 0.013 Identities = 40/144 (27%), Positives = 52/144 (36%), Gaps = 24/144 (16%) Query: 6 SLSPASSAKGRRPGGLPEEKKKAPPAGDE---ALGGYGAPPVGKGGKGESRLKRPSVLIS 62 S SP SS+ P G+P PP +LGG GAPP P + Sbjct: 80 SRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPP------------PPMPPP 127 Query: 63 ALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLA 122 L V +S+ G P P +GP Q + +L GGG+ P Sbjct: 128 PLGSPFPVISSSMGSPGLPPPAP-PGFSGPVSSPQINSTVSL--------PGGGSGPPED 178 Query: 123 VPVPTVPAAAATCEPPSGGSAAAQ 146 V P + C PP GG A + Sbjct: 179 VKPPVLGVRGLHCPPPPGGPGAGK 202 >gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] Length = 380 Score = 46.2 bits (108), Expect = 5e-05 Identities = 38/112 (33%), Positives = 48/112 (42%), Gaps = 15/112 (13%) Query: 87 PASTGPDPLVQQRNR-----ENLLRK-----GRDPPDGGGTAKPLAVPVPTVPAAAATCE 136 P P+ + QQ+ + E++ R+ G P GG P P P P Sbjct: 130 PNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPPGPPPPPGL- 188 Query: 137 PPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQASTGELLR 188 PPSG AAA G+GGG PPP PP P P GG+ + A G LR Sbjct: 189 PPSGVPAAAH--GAGGG--PPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLR 236 Score = 43.5 bits (101), Expect = 3e-04 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 14/86 (16%) Query: 113 DGGGTAKPLAVPVPTVPAAAATCEP---------PSGG-----SAAAQPPGSGGGKPPPP 158 +GGG P A+P +VP + E PS S A PP G PPPP Sbjct: 114 EGGGPPPPPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPP 173 Query: 159 PPPAPQVAPPVPGGSPRRVIVQASTG 184 P P P PP P G P + A+ G Sbjct: 174 PGPPPPPGPPPPPGLPPSGVPAAAHG 199 Score = 28.9 bits (63), Expect = 7.6 Identities = 27/96 (28%), Positives = 33/96 (34%), Gaps = 17/96 (17%) Query: 85 PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144 P P + GP P PP G P +P VPAAA +GG Sbjct: 163 PAPPAGGPPP-------------PPGPPPPPGPPPPPGLPPSGVPAAAHG----AGGGPP 205 Query: 145 AQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ 180 PP P AP +A + G R+V Q Sbjct: 206 PAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSKQ 241 >gi|148613878 acrosin precursor [Homo sapiens] Length = 421 Score = 46.2 bits (108), Expect = 5e-05 Identities = 40/148 (27%), Positives = 56/148 (37%), Gaps = 22/148 (14%) Query: 33 DEALGGYGAPPVGKGGKGESRLKRPSVLISALTWKRLVAAS--AKKKKGSKKVTPKPAST 90 D Y + G G +R KRP + + + +A+ + + + TP P +T Sbjct: 248 DSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPTT 307 Query: 91 GPDPLVQQRNRENLLRKGRDPPDGGGTA------KPLAVPVPTVPAAAATCEPPSGGSAA 144 P P+ R P +A +P P+P P AA PPS Sbjct: 308 RPPPI-------------RPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSP-PPP 353 Query: 145 AQPPGSGGGKPPPPPPPAPQVAPPVPGG 172 PP S PPPPPPP P +P G Sbjct: 354 PPPPASPLPPPPPPPPPTPSSTTKLPQG 381 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 46.2 bits (108), Expect = 5e-05 Identities = 31/88 (35%), Positives = 37/88 (42%), Gaps = 15/88 (17%) Query: 101 RENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEP-PSGGSAAAQPPGSGG---GKPP 156 R+ +++ G PL VP PT AAA P P+GG P G PP Sbjct: 1515 RQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPP 1574 Query: 157 PPPPP-----------APQVAPPVPGGS 173 PPPP APQ +PP PG S Sbjct: 1575 LPPPPESGPGQPGWEGAPQPSPPPPGPS 1602 Score = 32.0 bits (71), Expect = 0.90 Identities = 28/85 (32%), Positives = 33/85 (38%), Gaps = 25/85 (29%) Query: 120 PLAVPVPTVPAAAATCEPPSGGSAAAQPPG-SGGGK-----------------PPPPPPP 161 P P P AAA + P+ PPG S GK P PPP Sbjct: 840 PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899 Query: 162 APQVAP---PVPGGS----PRRVIV 179 A V+P P PGGS P +V+V Sbjct: 900 AQSVSPVQAPPPGGSAQLLPGKVLV 924 Score = 32.0 bits (71), Expect = 0.90 Identities = 41/165 (24%), Positives = 51/165 (30%), Gaps = 20/165 (12%) Query: 28 APPAGDEALGGY-GAP-PVGKGGKGESRLKRPSVLISALTWKRLVAASAKKKKGSKKVTP 85 A P G Y G+P P + PS++ + T AA+ K T Sbjct: 1085 AAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATA 1144 Query: 86 KPASTGPDPLVQQRNRENLL---RKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGS 142 PA T P P + L + R P K +P A P G Sbjct: 1145 TPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRP--GP 1202 Query: 143 AAAQPPGSG-------------GGKPPPPPPPAPQVAPPVPGGSP 174 A QP G G PP PPP P+ P SP Sbjct: 1203 APRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSP 1247 Score = 31.6 bits (70), Expect = 1.2 Identities = 32/112 (28%), Positives = 40/112 (35%), Gaps = 31/112 (27%) Query: 83 VTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPA--AAATCEPPSG 140 + P A + PDP VQ + + P+A PA AA E P G Sbjct: 40 LVPFLAPSQPDPSVQPSEAQQ------------PASHPVASNQSKEPAESAAVAHERPPG 87 Query: 141 GSAAAQP--------PGSGGGKPPPP---------PPPAPQVAPPVPGGSPR 175 G+ +A P P S G PP P PPP + P G PR Sbjct: 88 GTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPR 139 Score = 31.2 bits (69), Expect = 1.5 Identities = 28/77 (36%), Positives = 30/77 (38%), Gaps = 16/77 (20%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQP----------PGSG---GGKPPP 157 PP T P A P +P A G A PG G G+PP Sbjct: 1232 PPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPT 1291 Query: 158 PPPPAPQVAPPV-PGGS 173 PP PAP AP V PGGS Sbjct: 1292 PPSPAP--APAVAPGGS 1306 Score = 30.4 bits (67), Expect = 2.6 Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 7/70 (10%) Query: 115 GGTAKPLAVPVP-----TVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPV 169 G TA PL P P P+ A P + + P S GG PP P + APP Sbjct: 565 GSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP--SVIAAPPS 622 Query: 170 PGGSPRRVIV 179 GG+ + +V Sbjct: 623 GGGNILQTLV 632 Score = 30.0 bits (66), Expect = 3.4 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 5/79 (6%) Query: 110 DPP----DGGGTAKPLAVPVP-TVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQ 164 DPP G G+A + P + A+AAT G+ AQ G G P PPP Sbjct: 519 DPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGA 578 Query: 165 VAPPVPGGSPRRVIVQAST 183 P P + R + + +T Sbjct: 579 GGPATPSKATRFLPMDPAT 597 Score = 29.6 bits (65), Expect = 4.5 Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 2/58 (3%) Query: 129 PAAAATCEPPSGGSAAA--QPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQASTG 184 P A+ + P+ +A A +PPG G P PP A P PG +V++ G Sbjct: 65 PVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKG 122 Score = 28.5 bits (62), Expect = 10.0 Identities = 27/95 (28%), Positives = 37/95 (38%), Gaps = 24/95 (25%) Query: 112 PDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQP--------PGSGGGKPP------- 156 P GG+A+ L V VP AA + GG+ P P G +PP Sbjct: 909 PPPGGSAQLLPGKV-LVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLT 967 Query: 157 PPP--------PPAPQVAPPVPGGSPRRVIVQAST 183 P P PP P P P++V++ +ST Sbjct: 968 PVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSST 1002 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 45.8 bits (107), Expect = 6e-05 Identities = 27/95 (28%), Positives = 37/95 (38%), Gaps = 5/95 (5%) Query: 85 PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144 P+P P Q + + ++ +G P G G+A P + P + P SG Sbjct: 91 PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPT 150 Query: 145 AQPPGSGGGKPPPPPPPAP-----QVAPPVPGGSP 174 PP + PP PPP P PP GG P Sbjct: 151 PTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPP 185 Score = 38.1 bits (87), Expect = 0.013 Identities = 33/111 (29%), Positives = 38/111 (34%), Gaps = 12/111 (10%) Query: 72 ASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPP----DGGGTAKPLAVPVPT 127 AS+ + + P +GP P G PP G T P A P Sbjct: 127 ASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPP 186 Query: 128 VPAAAATCEPPSGGSAAAQPPGSGG---GKPPPPPPPAPQVAPPVPGGSPR 175 PAA P G Q PG GG GK P P P PGG P+ Sbjct: 187 PPAAV-----PGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPK 232 Score = 35.4 bits (80), Expect = 0.082 Identities = 23/80 (28%), Positives = 29/80 (36%), Gaps = 3/80 (3%) Query: 105 LRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQ 164 L + R P G P+P P +PP QPP +PPP P P Q Sbjct: 40 LNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPH---QPPPHPQPHQQ 96 Query: 165 VAPPVPGGSPRRVIVQASTG 184 PP P + +V G Sbjct: 97 QQPPPPPQDSSKPVVAQGPG 116 Score = 34.3 bits (77), Expect = 0.18 Identities = 26/97 (26%), Positives = 33/97 (34%), Gaps = 16/97 (16%) Query: 85 PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144 PKP P P QQ+ + PP +P P P +PP + Sbjct: 56 PKPPIPPPPPHQQQQ---------QPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDS 106 Query: 145 AQP-------PGSGGGKPPPPPPPAPQVAPPVPGGSP 174 ++P P G G PP AP PP G P Sbjct: 107 SKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP 143 Score = 30.0 bits (66), Expect = 3.4 Identities = 28/100 (28%), Positives = 35/100 (35%), Gaps = 35/100 (35%) Query: 85 PKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAA 144 P P P P Q+ + PP ++KP+ P P+ G + Sbjct: 82 PPPHQPPPHPQPHQQQQP--------PPPPQDSSKPVVAQGPG----------PAPGVGS 123 Query: 145 A----------------QPPGSGGGKPPPPPPPAPQVAPP 168 A PPGSG G P P PPPA APP Sbjct: 124 APPASSSAPPATPPTSGAPPGSGPG-PTPTPPPAVTSAPP 162 >gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 preproprotein [Homo sapiens] Length = 198 Score = 45.8 bits (107), Expect = 6e-05 Identities = 33/95 (34%), Positives = 34/95 (35%), Gaps = 11/95 (11%) Query: 86 KPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPV-------PTVPAAAATCEPP 138 KP P P Q K + PP G KP P P P PP Sbjct: 46 KPQGPPPPPGKPQGPPPQGGNKPQGPPPPG---KPQGPPPQGDKSRSPRSPPGKPQGPPP 102 Query: 139 SGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGS 173 GG PP GG KP PPPP PP GGS Sbjct: 103 QGGKPQGPPP-QGGNKPQGPPPPGKPQGPPAQGGS 136 Score = 38.1 bits (87), Expect = 0.013 Identities = 28/90 (31%), Positives = 33/90 (36%), Gaps = 14/90 (15%) Query: 96 VQQRNRENLLRKGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKP 155 V Q +L+ P G KP P P PP GG+ PP G + Sbjct: 23 VSQEESPSLIAGNPQGPSPQGGNKPQG---PPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 79 Query: 156 PPP----------PPPAPQVAPPVPGGSPR 175 PPP PP PQ PP GG P+ Sbjct: 80 PPPQGDKSRSPRSPPGKPQ-GPPPQGGKPQ 108 Score = 37.0 bits (84), Expect = 0.028 Identities = 27/71 (38%), Positives = 31/71 (43%), Gaps = 9/71 (12%) Query: 107 KGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKP--PPPPPPAPQ 164 K + PP GG KP P P P PP G + + P S GKP PPP PQ Sbjct: 56 KPQGPPPQGGN-KPQGPPPPGKPQGP----PPQGDKSRS--PRSPPGKPQGPPPQGGKPQ 108 Query: 165 VAPPVPGGSPR 175 PP G P+ Sbjct: 109 GPPPQGGNKPQ 119 Score = 35.0 bits (79), Expect = 0.11 Identities = 28/82 (34%), Positives = 31/82 (37%), Gaps = 18/82 (21%) Query: 107 KGRDPPDGGGTAKPLAVPVPTVPAAAATCEPPSGGS---AAAQPPGSGGGKP-------- 155 K + PP GG KP P P P P GGS +A PPG G P Sbjct: 106 KPQGPPPQGGN-KPQGPPPPGKPQGP----PAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 160 Query: 156 --PPPPPPAPQVAPPVPGGSPR 175 PPP PQ P G P+ Sbjct: 161 GPPPPAGGNPQQPQAPPAGQPQ 182 Score = 33.5 bits (75), Expect = 0.31 Identities = 50/183 (27%), Positives = 55/183 (30%), Gaps = 52/183 (28%) Query: 15 GRRPGGLPEEKKKAPPAGDEALGG---YGAPPVGK-------GGKGESRLKRPSVLISAL 64 G +P G P K P G GG G PP GK G K S P Sbjct: 44 GNKPQGPPPPPGK--PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG------ 95 Query: 65 TWKRLVAASAKKKKGSKKVTPKPAS----TGPDPLVQQRNRENLLRKGRDPPDGGGTAKP 120 +G K P P GP P K + PP GG+ Sbjct: 96 ------KPQGPPPQGGKPQGPPPQGGNKPQGPPPP----------GKPQGPPAQGGSKSQ 139 Query: 121 LAVPVPTVPAAAATCE-------PPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGS 173 A P P E PP G QP G+P PP P PQ GG Sbjct: 140 SARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP-PQ------GGR 192 Query: 174 PRR 176 P R Sbjct: 193 PSR 195 Score = 29.3 bits (64), Expect = 5.8 Identities = 35/154 (22%), Positives = 47/154 (30%), Gaps = 30/154 (19%) Query: 15 GRRPGGLPEEKKKA--PPAGDEALGGYGAP-----PVGKGGKGESRLKRPSVLISALTWK 67 G +P G P K PP GD++ P P +GGK + Sbjct: 65 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQG--------------- 109 Query: 68 RLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPLAVPVPT 127 + G+K P P P Q ++ R P G + P Sbjct: 110 ------PPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 163 Query: 128 VPAAAATCEP--PSGGSAAAQPPGSGGGKPPPPP 159 PA +P P G P GG+P PP Sbjct: 164 PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 197 >gi|117938310 sine oculis binding protein homolog [Homo sapiens] Length = 873 Score = 45.8 bits (107), Expect = 6e-05 Identities = 50/179 (27%), Positives = 63/179 (35%), Gaps = 17/179 (9%) Query: 2 GTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVLI 61 G LSL+P + GR + +PP A G G P V +G P + Sbjct: 603 GQALSLAPTPAEHGRSEVVDLTRRAGSPPGPPGAGGQLGFPGVLQG---------PQDGV 653 Query: 62 SALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKPL 121 LT V A+ + +P +R R G P G P Sbjct: 654 IDLT----VGHRARLHNVIHRALHAHVKAEREPSAAERRTCGGCRDGHCSPPAAGDPGPG 709 Query: 122 AVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPP-PPPAPQVAPPVPGGSPRRVIV 179 A P P AAA C G+ A G+ +PPP PPP P APP SP V Sbjct: 710 A---PAGPEAAAACNVIVNGTRGAAAEGAKSAEPPPEQPPPPPPPAPPKKLLSPEEPAV 765 Score = 34.7 bits (78), Expect = 0.14 Identities = 29/87 (33%), Positives = 35/87 (40%), Gaps = 12/87 (13%) Query: 85 PKPASTGPDPLVQQRNRENLLRKGRDPPDGGG-TAKPLAVPVPTVPAAAATCEPPSGGSA 143 P AS PL N + G PP GG P + P+ P + PPS + Sbjct: 416 PHHASNPNSPL------SNPMLPGIGPPPGGPRNLGPTSSPMHR-PMLSPHIHPPSTPTM 468 Query: 144 AAQPPGSGGGKPPPPPPPAPQVAPPVP 170 PPG PPPPP AP + P P Sbjct: 469 PGNPPGL----LPPPPPGAPLPSLPFP 491 Score = 30.0 bits (66), Expect = 3.4 Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 4/58 (6%) Query: 117 TAKPLAVPVPT-VPAAAATCEPPSGGSAAAQPPGSGG---GKPPPPPPPAPQVAPPVP 170 TA +PT VP + E P+ + QPP S G G PP PP PVP Sbjct: 337 TANCSVTKIPTPVPKSIPISETPNIPPVSVQPPASIGPPLGVPPRSPPMVMTNRGPVP 394 >gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo sapiens] Length = 1029 Score = 45.4 bits (106), Expect = 8e-05 Identities = 52/187 (27%), Positives = 72/187 (38%), Gaps = 28/187 (14%) Query: 19 GGLPEEKKKAPPAGDEALGGYG-APPVGKGGKGESRLKRPSVLISALTWKRLVAASAKKK 77 G + EE D + G+G PP G+ K E +R L+ K+ KKK Sbjct: 6 GEVSEESSSKVEQEDFVMEGHGKTPPPGEESKQEKEQEREEQLMED---KKRKKEDKKKK 62 Query: 78 KGSKKVTPKPASTGP--DPLVQQRNRENLLRKGRDPP-DGGGTAKPLAVPVPTVPAAAAT 134 + ++KVT + P + Q + + PP +GG AK +AVP P+AA Sbjct: 63 EATQKVTEQKTKVPEVTKPSLSQPTAASPIGSSPSPPVNGGNNAKRVAVPNGQPPSAARY 122 Query: 135 CE---PPSGGSAAAQPPGSGGGKPPPP----------PPPAPQVAPPVPGGSPRRVIVQA 181 PP G+PPPP PPP PG +P V Sbjct: 123 MPREVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGAGPPPC-----TAPGANPNNAQV-- 175 Query: 182 STGELLR 188 TG LL+ Sbjct: 176 -TGALLQ 181 >gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sapiens] Length = 2113 Score = 45.4 bits (106), Expect = 8e-05 Identities = 27/65 (41%), Positives = 30/65 (46%), Gaps = 8/65 (12%) Query: 118 AKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPP------PPPAPQVAPPVPG 171 +K L +P P PAAA+T P A PP G PP P PP AP APP P Sbjct: 2010 SKSLGLPHPGAPAAASTATLPQRTLAMPAPP--AGTAPPAPGPTPAEPPTAPSAAPPAPS 2067 Query: 172 GSPRR 176 P R Sbjct: 2068 TEPPR 2072 Score = 30.8 bits (68), Expect = 2.0 Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 3/42 (7%) Query: 111 PPDGGGTAKPLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGG 152 P GTA P P P P A + PP + + +PP +GG Sbjct: 2037 PAPPAGTAPPAPGPTPAEPPTAPSAAPP---APSTEPPRAGG 2075 >gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens] Length = 591 Score = 45.4 bits (106), Expect = 8e-05 Identities = 49/184 (26%), Positives = 63/184 (34%), Gaps = 22/184 (11%) Query: 8 SPASSAKGRRPGGLPEEKKKAPPAGDEALGGYG---APPVGKGGKGESRL----KRPSVL 60 SP A+ R+ G+PEE G G G GG G+ R KRP Sbjct: 104 SPPPPARARQENGMPEEPATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSS 163 Query: 61 ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDP-LVQQRNRENLLRKGRDPPDGGGTAK 119 + + + G TP+PA L R R D P G + Sbjct: 164 REGSGGPQESSRDKRPLSGPDVGTPQPAGLASGAKLAAGRPFNTYPRADTDHPSRGAQGE 223 Query: 120 PLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPP------------PPPPAPQVAP 167 P V P P+A P S S++++PP G P P PP AP Sbjct: 224 PHDV-APNGPSAGGLAIPQSS-SSSSRPPTRARGAPSPGVLGPHASEPQLAPPACTPAAP 281 Query: 168 PVPG 171 VPG Sbjct: 282 AVPG 285 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.135 0.419 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,386,077 Number of Sequences: 37866 Number of extensions: 1395354 Number of successful extensions: 31005 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 786 Number of HSP's successfully gapped in prelim test: 1172 Number of HSP's that attempted gapping in prelim test: 12243 Number of HSP's gapped (non-prelim): 11239 length of query: 367 length of database: 18,247,518 effective HSP length: 104 effective length of query: 263 effective length of database: 14,309,454 effective search space: 3763386402 effective search space used: 3763386402 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.