Guide to the Human Genome
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Search of human proteins with 4502101

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502101 annexin I [Homo sapiens]
         (346 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502101 annexin I [Homo sapiens]                                   678   0.0  
gi|4757756 annexin A2 isoform 2 [Homo sapiens]                        336   2e-92
gi|50845386 annexin A2 isoform 2 [Homo sapiens]                       336   2e-92
gi|50845388 annexin A2 isoform 1 [Homo sapiens]                       336   2e-92
gi|209862831 annexin A2 isoform 2 [Homo sapiens]                      336   2e-92
gi|4557317 annexin A11 [Homo sapiens]                                 294   9e-80
gi|22165433 annexin A11 [Homo sapiens]                                294   9e-80
gi|22165431 annexin A11 [Homo sapiens]                                294   9e-80
gi|4826643 annexin A3 [Homo sapiens]                                  294   9e-80
gi|4809279 annexin VII isoform 2 [Homo sapiens]                       278   5e-75
gi|4502111 annexin VII isoform 1 [Homo sapiens]                       278   5e-75
gi|71773415 annexin VI isoform 2 [Homo sapiens]                       271   8e-73
gi|4502105 annexin IV [Homo sapiens]                                  270   1e-72
gi|71773329 annexin VI isoform 1 [Homo sapiens]                       268   7e-72
gi|91823262 annexin A8 [Homo sapiens]                                 259   2e-69
gi|91807122 annexin A8L2 [Homo sapiens]                               258   5e-69
gi|149588958 annexin A8-like 1 [Homo sapiens]                         258   5e-69
gi|51896029 annexin A13 isoform b [Homo sapiens]                      258   5e-69
gi|51895795 annexin A13 isoform a [Homo sapiens]                      256   2e-68
gi|4502107 annexin 5 [Homo sapiens]                                   256   3e-68
gi|48762937 annexin A10 [Homo sapiens]                                219   4e-57
gi|145864465 annexin A9 [Homo sapiens]                                201   6e-52
gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo ...    95   8e-20
gi|188497635 cell division cycle associated 7-like isoform 2 [Ho...    31   1.9  
gi|31542537 cell division cycle associated 7-like isoform 1 [Hom...    31   1.9  
gi|148539855 epidermal growth factor receptor pathway substrate ...    30   2.4  
gi|148539853 epidermal growth factor receptor pathway substrate ...    30   2.4  
gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]               30   4.1  
gi|170650670 Leber congenital amaurosis 5 [Homo sapiens]               30   4.1  
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa...    29   5.4  

>gi|4502101 annexin I [Homo sapiens]
          Length = 346

 Score =  678 bits (1749), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGV 60
           MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGV
Sbjct: 1   MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGV 60

Query: 61  DEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDA 120
           DEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDA
Sbjct: 61  DEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDA 120

Query: 121 DELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNAL 180
           DELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNAL
Sbjct: 121 DELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNAL 180

Query: 181 LSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKY 240
           LSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKY
Sbjct: 181 LSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKY 240

Query: 241 TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM 300
           TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM
Sbjct: 241 TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM 300

Query: 301 VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346
           VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN
Sbjct: 301 VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346


>gi|4757756 annexin A2 isoform 2 [Homo sapiens]
          Length = 339

 Score =  336 bits (861), Expect = 2e-92
 Identities = 172/313 (54%), Positives = 228/313 (72%), Gaps = 1/313 (0%)

Query: 35  AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94
           +V  Y  F+   D   +  AI  KGVDE TI++ILT R+NAQRQ I  AY + T K L  
Sbjct: 26  SVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELAS 85

Query: 95  TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154
            LK AL+GHLE V+L LLKTPAQ+DA EL+A+MKGLGTDED+LIEI+ SRTN+E+++INR
Sbjct: 86  ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 145

Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERR 213
           VY+E  K DL KDI SDTSGDFR  +++LAKG R+ED  V + +L D DAR LY+AG +R
Sbjct: 146 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKR 205

Query: 214 KGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273
           KGTDV  + +I+T RS P L++VF +Y  YS +DM + +  E+KGD+E     +V+C  +
Sbjct: 206 KGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQN 265

Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333
           KP +FA++L+ +MKG GTR K LIRIMVSRSE+DM  I++ +++ YG SL   I  +TKG
Sbjct: 266 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 325

Query: 334 DYEKILVALCGGN 346
           DY+K L+ LCGG+
Sbjct: 326 DYQKALLYLCGGD 338


>gi|50845386 annexin A2 isoform 2 [Homo sapiens]
          Length = 339

 Score =  336 bits (861), Expect = 2e-92
 Identities = 172/313 (54%), Positives = 228/313 (72%), Gaps = 1/313 (0%)

Query: 35  AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94
           +V  Y  F+   D   +  AI  KGVDE TI++ILT R+NAQRQ I  AY + T K L  
Sbjct: 26  SVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELAS 85

Query: 95  TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154
            LK AL+GHLE V+L LLKTPAQ+DA EL+A+MKGLGTDED+LIEI+ SRTN+E+++INR
Sbjct: 86  ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 145

Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERR 213
           VY+E  K DL KDI SDTSGDFR  +++LAKG R+ED  V + +L D DAR LY+AG +R
Sbjct: 146 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKR 205

Query: 214 KGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273
           KGTDV  + +I+T RS P L++VF +Y  YS +DM + +  E+KGD+E     +V+C  +
Sbjct: 206 KGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQN 265

Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333
           KP +FA++L+ +MKG GTR K LIRIMVSRSE+DM  I++ +++ YG SL   I  +TKG
Sbjct: 266 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 325

Query: 334 DYEKILVALCGGN 346
           DY+K L+ LCGG+
Sbjct: 326 DYQKALLYLCGGD 338


>gi|50845388 annexin A2 isoform 1 [Homo sapiens]
          Length = 357

 Score =  336 bits (861), Expect = 2e-92
 Identities = 172/313 (54%), Positives = 228/313 (72%), Gaps = 1/313 (0%)

Query: 35  AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94
           +V  Y  F+   D   +  AI  KGVDE TI++ILT R+NAQRQ I  AY + T K L  
Sbjct: 44  SVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELAS 103

Query: 95  TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154
            LK AL+GHLE V+L LLKTPAQ+DA EL+A+MKGLGTDED+LIEI+ SRTN+E+++INR
Sbjct: 104 ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 163

Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERR 213
           VY+E  K DL KDI SDTSGDFR  +++LAKG R+ED  V + +L D DAR LY+AG +R
Sbjct: 164 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKR 223

Query: 214 KGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273
           KGTDV  + +I+T RS P L++VF +Y  YS +DM + +  E+KGD+E     +V+C  +
Sbjct: 224 KGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQN 283

Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333
           KP +FA++L+ +MKG GTR K LIRIMVSRSE+DM  I++ +++ YG SL   I  +TKG
Sbjct: 284 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 343

Query: 334 DYEKILVALCGGN 346
           DY+K L+ LCGG+
Sbjct: 344 DYQKALLYLCGGD 356


>gi|209862831 annexin A2 isoform 2 [Homo sapiens]
          Length = 339

 Score =  336 bits (861), Expect = 2e-92
 Identities = 172/313 (54%), Positives = 228/313 (72%), Gaps = 1/313 (0%)

Query: 35  AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94
           +V  Y  F+   D   +  AI  KGVDE TI++ILT R+NAQRQ I  AY + T K L  
Sbjct: 26  SVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELAS 85

Query: 95  TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154
            LK AL+GHLE V+L LLKTPAQ+DA EL+A+MKGLGTDED+LIEI+ SRTN+E+++INR
Sbjct: 86  ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 145

Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERR 213
           VY+E  K DL KDI SDTSGDFR  +++LAKG R+ED  V + +L D DAR LY+AG +R
Sbjct: 146 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKR 205

Query: 214 KGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273
           KGTDV  + +I+T RS P L++VF +Y  YS +DM + +  E+KGD+E     +V+C  +
Sbjct: 206 KGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQN 265

Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333
           KP +FA++L+ +MKG GTR K LIRIMVSRSE+DM  I++ +++ YG SL   I  +TKG
Sbjct: 266 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 325

Query: 334 DYEKILVALCGGN 346
           DY+K L+ LCGG+
Sbjct: 326 DYQKALLYLCGGD 338


>gi|4557317 annexin A11 [Homo sapiens]
          Length = 505

 Score =  294 bits (752), Expect = 9e-80
 Identities = 153/322 (47%), Positives = 214/322 (66%)

Query: 25  VKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAY 84
           V  ++ G    ++  P F+P  D   L KA+   G DE  IID L  R+N QRQQI  ++
Sbjct: 183 VPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSF 242

Query: 85  LQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASR 144
               GK L + LK  L+G+ E+ +LAL+KTP  FD  E++ A+KG+GTDE  LIEILASR
Sbjct: 243 KTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASR 302

Query: 145 TNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDAR 204
           +N+ IR++NR Y+ E K+ L + I SDTSG F+  L+SL++G+R E   V+  LA  DA+
Sbjct: 303 SNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQ 362

Query: 205 ALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCL 264
            LY AGE R GTD + FN +L +RS   L  VF +Y + +  D+ K +  E+ GD+E+ +
Sbjct: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422

Query: 265 TAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLC 324
            A+VKC  + PAFFAE+L++AM+G GT+ + LIRIMVSRSE D+ DI++ Y++MYG SL 
Sbjct: 423 LAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLY 482

Query: 325 QAILDETKGDYEKILVALCGGN 346
             I  +T GDY KIL+ +CGGN
Sbjct: 483 HDISGDTSGDYRKILLKICGGN 504


>gi|22165433 annexin A11 [Homo sapiens]
          Length = 505

 Score =  294 bits (752), Expect = 9e-80
 Identities = 153/322 (47%), Positives = 214/322 (66%)

Query: 25  VKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAY 84
           V  ++ G    ++  P F+P  D   L KA+   G DE  IID L  R+N QRQQI  ++
Sbjct: 183 VPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSF 242

Query: 85  LQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASR 144
               GK L + LK  L+G+ E+ +LAL+KTP  FD  E++ A+KG+GTDE  LIEILASR
Sbjct: 243 KTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASR 302

Query: 145 TNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDAR 204
           +N+ IR++NR Y+ E K+ L + I SDTSG F+  L+SL++G+R E   V+  LA  DA+
Sbjct: 303 SNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQ 362

Query: 205 ALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCL 264
            LY AGE R GTD + FN +L +RS   L  VF +Y + +  D+ K +  E+ GD+E+ +
Sbjct: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422

Query: 265 TAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLC 324
            A+VKC  + PAFFAE+L++AM+G GT+ + LIRIMVSRSE D+ DI++ Y++MYG SL 
Sbjct: 423 LAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLY 482

Query: 325 QAILDETKGDYEKILVALCGGN 346
             I  +T GDY KIL+ +CGGN
Sbjct: 483 HDISGDTSGDYRKILLKICGGN 504


>gi|22165431 annexin A11 [Homo sapiens]
          Length = 505

 Score =  294 bits (752), Expect = 9e-80
 Identities = 153/322 (47%), Positives = 214/322 (66%)

Query: 25  VKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAY 84
           V  ++ G    ++  P F+P  D   L KA+   G DE  IID L  R+N QRQQI  ++
Sbjct: 183 VPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSF 242

Query: 85  LQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASR 144
               GK L + LK  L+G+ E+ +LAL+KTP  FD  E++ A+KG+GTDE  LIEILASR
Sbjct: 243 KTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASR 302

Query: 145 TNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDAR 204
           +N+ IR++NR Y+ E K+ L + I SDTSG F+  L+SL++G+R E   V+  LA  DA+
Sbjct: 303 SNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQ 362

Query: 205 ALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCL 264
            LY AGE R GTD + FN +L +RS   L  VF +Y + +  D+ K +  E+ GD+E+ +
Sbjct: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422

Query: 265 TAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLC 324
            A+VKC  + PAFFAE+L++AM+G GT+ + LIRIMVSRSE D+ DI++ Y++MYG SL 
Sbjct: 423 LAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLY 482

Query: 325 QAILDETKGDYEKILVALCGGN 346
             I  +T GDY KIL+ +CGGN
Sbjct: 483 HDISGDTSGDYRKILLKICGGN 504


>gi|4826643 annexin A3 [Homo sapiens]
          Length = 323

 Score =  294 bits (752), Expect = 9e-80
 Identities = 157/316 (49%), Positives = 207/316 (65%)

Query: 31  GPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGK 90
           G    V  YP F+PS D  A+ KAI   G DE  +I ILT+R+NAQRQ I   Y    GK
Sbjct: 7   GHRGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGK 66

Query: 91  PLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIR 150
            L + LK  L+GH E +++AL+  PA FDA +L+ +MKG GT+ED LIEIL +RT+++++
Sbjct: 67  ELKDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMK 126

Query: 151 DINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAG 210
           DI++ Y    K+ L  DI+S+TSGDFR ALL+LA G R E   V+E LA  DA+ LY+AG
Sbjct: 127 DISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAG 186

Query: 211 ERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKC 270
           E R GTD + F  IL  RS+PQL+  F +Y   S+ D+   +  EL G  E  L AIV C
Sbjct: 187 ENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNC 246

Query: 271 ATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDE 330
             + PAF AE+LH+A+KG+GT    L RIMVSRSEID+ DI+  ++K YG SL  AI  +
Sbjct: 247 VRNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSD 306

Query: 331 TKGDYEKILVALCGGN 346
           T GDYE  L+ +CGG+
Sbjct: 307 TSGDYEITLLKICGGD 322


>gi|4809279 annexin VII isoform 2 [Homo sapiens]
          Length = 488

 Score =  278 bits (711), Expect = 5e-75
 Identities = 143/309 (46%), Positives = 200/309 (64%)

Query: 36  VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95
           + P   F+   D   L KA+   G DE  I+D++  R+N QRQ+IKAA+    GK L + 
Sbjct: 179 IRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKD 238

Query: 96  LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155
           LK  L+G++EE++LAL   P  +DA  LR AM+G GT E  LIEIL +RTN+EIR+I R 
Sbjct: 239 LKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRC 298

Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKG 215
           Y+ E  RDL KDI SDTSG F   L+S+ +G+R E+  +N  +A  DA+ LY+AGE R G
Sbjct: 299 YQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLG 358

Query: 216 TDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKP 275
           TD + FN IL TRS+PQLR   + Y++ +  D+   +  E  G +E  L  I++CA ++P
Sbjct: 359 TDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRP 418

Query: 276 AFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDY 335
           AFFAE+L+ AMKG GT    L+RI+V+RSEID+  IK  + +MY  +L   I  +T GDY
Sbjct: 419 AFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDY 478

Query: 336 EKILVALCG 344
            ++L+A+ G
Sbjct: 479 RRLLLAIVG 487



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 43/133 (32%), Positives = 74/133 (55%), Gaps = 5/133 (3%)

Query: 215 GTDVNVFNTILTTRSYPQLRRVFQKY-TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273
           GTD      ++  RS  Q +++   + T Y K D+ K L  EL G++E+ + A+    T 
Sbjct: 202 GTDEQAIVDVVANRSNDQRQKIKAAFKTSYGK-DLIKDLKSELSGNMEELILALFMPPTY 260

Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333
             A+    L +AM+G GT+ + LI I+ +R+  ++ +I   YQ  +G  L + I  +T G
Sbjct: 261 YDAW---SLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSG 317

Query: 334 DYEKILVALCGGN 346
            +E++LV++C GN
Sbjct: 318 HFERLLVSMCQGN 330


>gi|4502111 annexin VII isoform 1 [Homo sapiens]
          Length = 466

 Score =  278 bits (711), Expect = 5e-75
 Identities = 143/309 (46%), Positives = 200/309 (64%)

Query: 36  VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95
           + P   F+   D   L KA+   G DE  I+D++  R+N QRQ+IKAA+    GK L + 
Sbjct: 157 IRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKD 216

Query: 96  LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155
           LK  L+G++EE++LAL   P  +DA  LR AM+G GT E  LIEIL +RTN+EIR+I R 
Sbjct: 217 LKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRC 276

Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKG 215
           Y+ E  RDL KDI SDTSG F   L+S+ +G+R E+  +N  +A  DA+ LY+AGE R G
Sbjct: 277 YQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLG 336

Query: 216 TDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKP 275
           TD + FN IL TRS+PQLR   + Y++ +  D+   +  E  G +E  L  I++CA ++P
Sbjct: 337 TDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRP 396

Query: 276 AFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDY 335
           AFFAE+L+ AMKG GT    L+RI+V+RSEID+  IK  + +MY  +L   I  +T GDY
Sbjct: 397 AFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDY 456

Query: 336 EKILVALCG 344
            ++L+A+ G
Sbjct: 457 RRLLLAIVG 465



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 43/133 (32%), Positives = 74/133 (55%), Gaps = 5/133 (3%)

Query: 215 GTDVNVFNTILTTRSYPQLRRVFQKY-TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273
           GTD      ++  RS  Q +++   + T Y K D+ K L  EL G++E+ + A+    T 
Sbjct: 180 GTDEQAIVDVVANRSNDQRQKIKAAFKTSYGK-DLIKDLKSELSGNMEELILALFMPPTY 238

Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333
             A+    L +AM+G GT+ + LI I+ +R+  ++ +I   YQ  +G  L + I  +T G
Sbjct: 239 YDAW---SLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSG 295

Query: 334 DYEKILVALCGGN 346
            +E++LV++C GN
Sbjct: 296 HFERLLVSMCQGN 308


>gi|71773415 annexin VI isoform 2 [Homo sapiens]
          Length = 667

 Score =  271 bits (692), Expect = 8e-73
 Identities = 148/310 (47%), Positives = 198/310 (63%), Gaps = 1/310 (0%)

Query: 36  VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95
           V P   FNP +D  AL KA+   G DE TIIDI+T R+N QRQQI+  +    G+ L   
Sbjct: 357 VRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTD 416

Query: 96  LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155
           LK  ++G L  ++L L+  PA +DA +L+ AM+G GTDE  LIEILA+RTN EIR IN  
Sbjct: 417 LKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEA 476

Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKG 215
           Y+E+  + L   ++SDTSG FR  L+SLA G R E+ G N D A  DA+ + +     K 
Sbjct: 477 YKEDYHKSLEDALSSDTSGHFRRILISLATGHR-EEGGENLDQAREDAQEIADTPSGDKT 535

Query: 216 TDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKP 275
           +    F TIL TRSYP LRRVFQ++ K + +D+   +  E+ GD+     AIV+   +KP
Sbjct: 536 SLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKP 595

Query: 276 AFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDY 335
            FFA+KL+++MKG GT  K L RIMVSRSEID+ +I+  + + Y  SL QAI  +T GD+
Sbjct: 596 LFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDF 655

Query: 336 EKILVALCGG 345
            K L+ALCGG
Sbjct: 656 LKALLALCGG 665



 Score =  262 bits (670), Expect = 3e-70
 Identities = 141/312 (45%), Positives = 197/312 (63%)

Query: 35  AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94
           ++  +P F+P+ D  AL+ A+   G D+  I+DI+T R+N QRQ++  +Y    GK L  
Sbjct: 13  SIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIA 72

Query: 95  TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154
            LK  LTG  E +++ L++ PA  DA E++ A+ G+GTDE  LIEILASRTN+++  +  
Sbjct: 73  DLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVA 132

Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRK 214
            Y++  +RDL  DI  DTSG F+  L+ L +G R ED  V+EDL   D + LYEAGE + 
Sbjct: 133 AYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKW 192

Query: 215 GTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSK 274
           GTD   F  IL  RS   LR VF +Y K +   +   +  EL GD EK + A+VKC  S 
Sbjct: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRST 252

Query: 275 PAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGD 334
           P +FAE+L +AMKG+GTR   LIRIMVSRSE+DM DI+  ++  Y  SL   I ++T G+
Sbjct: 253 PEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGE 312

Query: 335 YEKILVALCGGN 346
           Y+K L+ L GG+
Sbjct: 313 YKKTLLKLSGGD 324



 Score =  150 bits (378), Expect = 2e-36
 Identities = 108/335 (32%), Positives = 181/335 (54%), Gaps = 41/335 (12%)

Query: 47  DVAALHKAIMVK-GVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLE 105
           DV  L++A  +K G DEA  I IL  R+    + +   YL+ TGKP++ +++  L+G  E
Sbjct: 180 DVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFE 239

Query: 106 EVVLALLK----TPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELK 161
           +++LA++K    TP  F A+ L  AMKGLGT ++TLI I+ SR+  ++ DI  ++R + +
Sbjct: 240 KLMLAVVKCIRSTPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYE 298

Query: 162 RDLAKDITSDTSGDFRNALLSLAKGD-------------------------RSEDFGV-- 194
           + L   I +DTSG+++  LL L+ GD                         R E  G   
Sbjct: 299 KSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVR 358

Query: 195 --NEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVL 252
             N+   D+DA+AL +A  +  GTD +    I+T RS  Q +++ Q +  +   D+   L
Sbjct: 359 PANDFNPDADAKALRKA-MKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDL 417

Query: 253 DLELKGDIEKCLTAIVKCATSKPAFF-AEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDI 311
             E+ GD+ + +  ++      PA + A++L +AM+G GT  KALI I+ +R+  ++  I
Sbjct: 418 KSEISGDLARLILGLMM----PPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473

Query: 312 KAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346
              Y++ Y  SL  A+  +T G + +IL++L  G+
Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGH 508



 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 43/129 (33%), Positives = 74/129 (57%), Gaps = 3/129 (2%)

Query: 62  EATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALL---KTPAQF 118
           E   + IL  R+    +++   +++ T   ++ T+KK ++G + +  +A++   K    F
Sbjct: 538 ETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLF 597

Query: 119 DADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRN 178
            AD+L  +MKG GTDE TL  I+ SR+  ++ +I R + E+  + L + I  DTSGDF  
Sbjct: 598 FADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLK 657

Query: 179 ALLSLAKGD 187
           ALL+L  G+
Sbjct: 658 ALLALCGGE 666


>gi|4502105 annexin IV [Homo sapiens]
          Length = 321

 Score =  270 bits (691), Expect = 1e-72
 Identities = 147/320 (45%), Positives = 204/320 (63%), Gaps = 3/320 (0%)

Query: 27  SSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQ 86
           ++KGG   A S    FN   D   L KA+   G DE  II +L  RN AQRQ+I+ AY  
Sbjct: 4   ATKGGTVKAASG---FNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKS 60

Query: 87  ETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTN 146
             G+ L + LK  L+G+ E+V++ ++     +D  ELR AMKG GTDE  LIEILASRT 
Sbjct: 61  TIGRDLIDDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTP 120

Query: 147 KEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARAL 206
           +EIR I++ Y+++  R L  DI SDTS  F+  L+SL+ G R E   +++ L   DA+ L
Sbjct: 121 EEIRRISQTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDL 180

Query: 207 YEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTA 266
           YEAGE++ GTD   F T+L +R+   L  VF +Y + S+ D+ + +  E  G  E  L A
Sbjct: 181 YEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLA 240

Query: 267 IVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQA 326
           IVKC  +K A+FAEKL+++MKG+GT    LIR+MVSR+EIDM DI+A ++++YG SL   
Sbjct: 241 IVKCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSF 300

Query: 327 ILDETKGDYEKILVALCGGN 346
           I  +T GDY K+L+ LCGG+
Sbjct: 301 IKGDTSGDYRKVLLVLCGGD 320


>gi|71773329 annexin VI isoform 1 [Homo sapiens]
          Length = 673

 Score =  268 bits (684), Expect = 7e-72
 Identities = 149/316 (47%), Positives = 200/316 (63%), Gaps = 7/316 (2%)

Query: 36  VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95
           V P   FNP +D  AL KA+   G DE TIIDI+T R+N QRQQI+  +    G+ L   
Sbjct: 357 VRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTD 416

Query: 96  LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155
           LK  ++G L  ++L L+  PA +DA +L+ AM+G GTDE  LIEILA+RTN EIR IN  
Sbjct: 417 LKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEA 476

Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARA---LYEAGER 212
           Y+E+  + L   ++SDTSG FR  L+SLA G R E+ G N D A  DA+    + E  + 
Sbjct: 477 YKEDYHKSLEDALSSDTSGHFRRILISLATGHR-EEGGENLDQAREDAQVAAEILEIADT 535

Query: 213 RKGTDVNV---FNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVK 269
             G   ++   F TIL TRSYP LRRVFQ++ K + +D+   +  E+ GD+     AIV+
Sbjct: 536 PSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQ 595

Query: 270 CATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILD 329
              +KP FFA+KL+++MKG GT  K L RIMVSRSEID+ +I+  + + Y  SL QAI  
Sbjct: 596 SVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEG 655

Query: 330 ETKGDYEKILVALCGG 345
           +T GD+ K L+ALCGG
Sbjct: 656 DTSGDFLKALLALCGG 671



 Score =  262 bits (670), Expect = 3e-70
 Identities = 141/312 (45%), Positives = 197/312 (63%)

Query: 35  AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94
           ++  +P F+P+ D  AL+ A+   G D+  I+DI+T R+N QRQ++  +Y    GK L  
Sbjct: 13  SIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIA 72

Query: 95  TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154
            LK  LTG  E +++ L++ PA  DA E++ A+ G+GTDE  LIEILASRTN+++  +  
Sbjct: 73  DLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVA 132

Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRK 214
            Y++  +RDL  DI  DTSG F+  L+ L +G R ED  V+EDL   D + LYEAGE + 
Sbjct: 133 AYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKW 192

Query: 215 GTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSK 274
           GTD   F  IL  RS   LR VF +Y K +   +   +  EL GD EK + A+VKC  S 
Sbjct: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRST 252

Query: 275 PAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGD 334
           P +FAE+L +AMKG+GTR   LIRIMVSRSE+DM DI+  ++  Y  SL   I ++T G+
Sbjct: 253 PEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGE 312

Query: 335 YEKILVALCGGN 346
           Y+K L+ L GG+
Sbjct: 313 YKKTLLKLSGGD 324



 Score =  150 bits (378), Expect = 2e-36
 Identities = 108/335 (32%), Positives = 181/335 (54%), Gaps = 41/335 (12%)

Query: 47  DVAALHKAIMVK-GVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLE 105
           DV  L++A  +K G DEA  I IL  R+    + +   YL+ TGKP++ +++  L+G  E
Sbjct: 180 DVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFE 239

Query: 106 EVVLALLK----TPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELK 161
           +++LA++K    TP  F A+ L  AMKGLGT ++TLI I+ SR+  ++ DI  ++R + +
Sbjct: 240 KLMLAVVKCIRSTPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYE 298

Query: 162 RDLAKDITSDTSGDFRNALLSLAKGD-------------------------RSEDFGV-- 194
           + L   I +DTSG+++  LL L+ GD                         R E  G   
Sbjct: 299 KSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVR 358

Query: 195 --NEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVL 252
             N+   D+DA+AL +A  +  GTD +    I+T RS  Q +++ Q +  +   D+   L
Sbjct: 359 PANDFNPDADAKALRKA-MKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDL 417

Query: 253 DLELKGDIEKCLTAIVKCATSKPAFF-AEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDI 311
             E+ GD+ + +  ++      PA + A++L +AM+G GT  KALI I+ +R+  ++  I
Sbjct: 418 KSEISGDLARLILGLMM----PPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473

Query: 312 KAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346
              Y++ Y  SL  A+  +T G + +IL++L  G+
Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGH 508



 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 43/129 (33%), Positives = 74/129 (57%), Gaps = 3/129 (2%)

Query: 62  EATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALL---KTPAQF 118
           E   + IL  R+    +++   +++ T   ++ T+KK ++G + +  +A++   K    F
Sbjct: 544 ETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLF 603

Query: 119 DADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRN 178
            AD+L  +MKG GTDE TL  I+ SR+  ++ +I R + E+  + L + I  DTSGDF  
Sbjct: 604 FADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLK 663

Query: 179 ALLSLAKGD 187
           ALL+L  G+
Sbjct: 664 ALLALCGGE 672


>gi|91823262 annexin A8 [Homo sapiens]
          Length = 327

 Score =  259 bits (663), Expect = 2e-69
 Identities = 149/337 (44%), Positives = 207/337 (61%), Gaps = 13/337 (3%)

Query: 11  AWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILT 70
           AW+    EQE V TVKSS             FNP  D   L+KA+   G +E  IID+LT
Sbjct: 2   AWWKSWIEQEGV-TVKSSSH-----------FNPDPDAETLYKAMKGIGTNEQAIIDVLT 49

Query: 71  KRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGL 130
           KR+N QRQQI  ++  + GK L ETLK  L+G  E +++AL+  P +++A EL  AMKGL
Sbjct: 50  KRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGL 109

Query: 131 GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSE 190
           GT E  +IEILASRT  ++R+I + Y E+    L +DI +DTSG     L+ L +G R +
Sbjct: 110 GTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDD 169

Query: 191 -DFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMN 249
               V+  LA  DA+ LY AGE+ +GTD   F TIL TRS   L RVF++Y K +   + 
Sbjct: 170 VSSFVDPGLALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIE 229

Query: 250 KVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMN 309
             +  E  G +E+ +  +VKC  +  ++FAE+L+ AMKG GTR   LIR +VSRSEID+N
Sbjct: 230 DSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLN 289

Query: 310 DIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346
            IK  ++KMYG +L   I+++T GDY+  L++L G +
Sbjct: 290 LIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSD 326


>gi|91807122 annexin A8L2 [Homo sapiens]
          Length = 327

 Score =  258 bits (659), Expect = 5e-69
 Identities = 149/337 (44%), Positives = 206/337 (61%), Gaps = 13/337 (3%)

Query: 11  AWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILT 70
           AW+    EQE V TVKSS             FNP  D   L+KA+   G +E  IID+LT
Sbjct: 2   AWWKAWIEQEGV-TVKSSSH-----------FNPDPDAETLYKAMKGIGTNEQAIIDVLT 49

Query: 71  KRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGL 130
           KR+N QRQQI  ++  + GK L ETLK  L+G  E +++AL+  P +++A EL  AMKGL
Sbjct: 50  KRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGL 109

Query: 131 GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSE 190
           GT E  +IEILASRT  ++R+I + Y E+    L +DI +DTSG     L+ L +G R +
Sbjct: 110 GTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDD 169

Query: 191 -DFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMN 249
               V+  LA  DA+ LY AGE  +GTD   F TIL TRS   L RVF++Y K +   + 
Sbjct: 170 VSSFVDPALALQDAQDLYAAGENIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIE 229

Query: 250 KVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMN 309
             +  E  G +E+ +  +VKC  +  ++FAE+L+ AMKG GTR   LIR +VSRSEID+N
Sbjct: 230 DSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLN 289

Query: 310 DIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346
            IK  ++KMYG +L   I+++T GDY+  L++L G +
Sbjct: 290 LIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSD 326


>gi|149588958 annexin A8-like 1 [Homo sapiens]
          Length = 327

 Score =  258 bits (659), Expect = 5e-69
 Identities = 148/337 (43%), Positives = 207/337 (61%), Gaps = 13/337 (3%)

Query: 11  AWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILT 70
           AW+    EQE V TVKSS             FNP  D   L++A+   G +E  IID+LT
Sbjct: 2   AWWKSWIEQEGV-TVKSSSH-----------FNPDPDAETLYQAMKGIGTNEQAIIDVLT 49

Query: 71  KRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGL 130
           KR+N QRQQI  ++  + GK L ETLK  L+G  E +++AL+  P +++A EL  AMKGL
Sbjct: 50  KRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGL 109

Query: 131 GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSE 190
           GT E  +IEILASRT  ++R+I + Y E+    L +DI +DTSG     L+ L +G R +
Sbjct: 110 GTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDD 169

Query: 191 -DFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMN 249
               V+  LA  DA+ LY AGE+ +GTD   F TIL TRS   L RVF++Y K +   + 
Sbjct: 170 VSSFVDPGLALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIE 229

Query: 250 KVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMN 309
             +  E  G +E+ +  +VKC  +  ++FAE+L+ AMKG GTR   LIR +VSRSEID+N
Sbjct: 230 DSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLN 289

Query: 310 DIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346
            IK  ++KMYG +L   I+++T GDY+  L++L G +
Sbjct: 290 LIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSD 326


>gi|51896029 annexin A13 isoform b [Homo sapiens]
          Length = 357

 Score =  258 bits (659), Expect = 5e-69
 Identities = 139/311 (44%), Positives = 195/311 (62%), Gaps = 1/311 (0%)

Query: 32  PGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKP 91
           P  A SP   F+   D   L+KA    G +EA II+IL+ R + +RQQIK  Y    GK 
Sbjct: 46  PAKASSPQG-FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKE 104

Query: 92  LDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRD 151
           L+E LK  L+G+ E+  LALL  P+++ A +L+ AMKGLGTDE  LIE+L +RTNKEI  
Sbjct: 105 LEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIA 164

Query: 152 INRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGE 211
           I   Y+    R L  D+  DTSG+ +  L+SL + +R+E   V++DLA  DA+ LY+AGE
Sbjct: 165 IKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGE 224

Query: 212 RRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCA 271
            R GTD   FN +L  RSY QLR  FQ Y      D+ + ++ E  GD++K    +V+CA
Sbjct: 225 GRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCA 284

Query: 272 TSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDET 331
                +FAE+L+++MKG GT  + LIRI+V+R+E+D+  IKA +Q+ Y  SL   +  +T
Sbjct: 285 QDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDT 344

Query: 332 KGDYEKILVAL 342
            GD+ K+LVAL
Sbjct: 345 SGDFRKLLVAL 355



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 72/263 (27%), Positives = 128/263 (48%), Gaps = 22/263 (8%)

Query: 19  QEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAA-LHKAIMVKGVDEATIIDILTKRNNAQR 77
           +E  + +KS   G     +      PS   A  L KA+   G DE+ +I++L  R N + 
Sbjct: 103 KELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEI 162

Query: 78  QQIKAAYLQETGKPLDETLKKALTGHLEEVVLALL-----------KTPAQFDADELRAA 126
             IK AY +   + L+  +K   +G+L++++++LL           K  A  DA +L  A
Sbjct: 163 IAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDA 222

Query: 127 MKGL-GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAK 185
            +G  GTDE    E+LA R+ K++R   + Y+  + +D+ + I  +TSGD + A L+L +
Sbjct: 223 GEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVR 282

Query: 186 GDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSK 245
                     +D  D  A  LY++  +  GTD      I+ TR+   L+ +  K+ +  +
Sbjct: 283 --------CAQDCEDYFAERLYKS-MKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 333

Query: 246 HDMNKVLDLELKGDIEKCLTAIV 268
             ++ ++  +  GD  K L A++
Sbjct: 334 KSLSDMVRSDTSGDFRKLLVALL 356



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 51/164 (31%), Positives = 88/164 (53%), Gaps = 11/164 (6%)

Query: 184 AKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKY 243
           AK    + F V     D DA+ L +A  +  GT+      IL+ R+  + +++ QKY   
Sbjct: 47  AKASSPQGFDV-----DRDAKKLNKAC-KGMGTNEAAIIEILSGRTSDERQQIKQKYKAT 100

Query: 244 SKHDMNKVLDLELKGDIEKCLTAIVKCATSKPA-FFAEKLHQAMKGVGTRHKALIRIMVS 302
              ++ +VL  EL G+ EK   A++     +P+ + A +L +AMKG+GT    LI ++ +
Sbjct: 101 YGKELEEVLKSELSGNFEKTALALL----DRPSEYAARQLQKAMKGLGTDESVLIEVLCT 156

Query: 303 RSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346
           R+  ++  IK  YQ+++  SL   +  +T G+ +KILV+L   N
Sbjct: 157 RTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 200


>gi|51895795 annexin A13 isoform a [Homo sapiens]
          Length = 316

 Score =  256 bits (654), Expect = 2e-68
 Identities = 135/301 (44%), Positives = 191/301 (63%)

Query: 42  FNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALT 101
           F+   D   L+KA    G +EA II+IL+ R + +RQQIK  Y    GK L+E LK  L+
Sbjct: 14  FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73

Query: 102 GHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELK 161
           G+ E+  LALL  P+++ A +L+ AMKGLGTDE  LIE+L +RTNKEI  I   Y+    
Sbjct: 74  GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133

Query: 162 RDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVF 221
           R L  D+  DTSG+ +  L+SL + +R+E   V++DLA  DA+ LY+AGE R GTD   F
Sbjct: 134 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 193

Query: 222 NTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEK 281
           N +L  RSY QLR  FQ Y      D+ + ++ E  GD++K    +V+CA     +FAE+
Sbjct: 194 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 253

Query: 282 LHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVA 341
           L+++MKG GT  + LIRI+V+R+E+D+  IKA +Q+ Y  SL   +  +T GD+ K+LVA
Sbjct: 254 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 313

Query: 342 L 342
           L
Sbjct: 314 L 314



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 72/263 (27%), Positives = 128/263 (48%), Gaps = 22/263 (8%)

Query: 19  QEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAA-LHKAIMVKGVDEATIIDILTKRNNAQR 77
           +E  + +KS   G     +      PS   A  L KA+   G DE+ +I++L  R N + 
Sbjct: 62  KELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEI 121

Query: 78  QQIKAAYLQETGKPLDETLKKALTGHLEEVVLALL-----------KTPAQFDADELRAA 126
             IK AY +   + L+  +K   +G+L++++++LL           K  A  DA +L  A
Sbjct: 122 IAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDA 181

Query: 127 MKGL-GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAK 185
            +G  GTDE    E+LA R+ K++R   + Y+  + +D+ + I  +TSGD + A L+L +
Sbjct: 182 GEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVR 241

Query: 186 GDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSK 245
                     +D  D  A  LY++  +  GTD      I+ TR+   L+ +  K+ +  +
Sbjct: 242 --------CAQDCEDYFAERLYKS-MKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 292

Query: 246 HDMNKVLDLELKGDIEKCLTAIV 268
             ++ ++  +  GD  K L A++
Sbjct: 293 KSLSDMVRSDTSGDFRKLLVALL 315



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 51/164 (31%), Positives = 88/164 (53%), Gaps = 11/164 (6%)

Query: 184 AKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKY 243
           AK    + F V     D DA+ L +A  +  GT+      IL+ R+  + +++ QKY   
Sbjct: 6   AKASSPQGFDV-----DRDAKKLNKAC-KGMGTNEAAIIEILSGRTSDERQQIKQKYKAT 59

Query: 244 SKHDMNKVLDLELKGDIEKCLTAIVKCATSKPA-FFAEKLHQAMKGVGTRHKALIRIMVS 302
              ++ +VL  EL G+ EK   A++     +P+ + A +L +AMKG+GT    LI ++ +
Sbjct: 60  YGKELEEVLKSELSGNFEKTALALL----DRPSEYAARQLQKAMKGLGTDESVLIEVLCT 115

Query: 303 RSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346
           R+  ++  IK  YQ+++  SL   +  +T G+ +KILV+L   N
Sbjct: 116 RTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 159


>gi|4502107 annexin 5 [Homo sapiens]
          Length = 320

 Score =  256 bits (653), Expect = 3e-68
 Identities = 137/309 (44%), Positives = 196/309 (63%)

Query: 36  VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95
           V+ +P F+  +D   L KA+   G DE +I+ +LT R+NAQRQ+I AA+    G+ L + 
Sbjct: 9   VTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDD 68

Query: 96  LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155
           LK  LTG  E++++AL+K    +DA EL+ A+KG GT+E  L EI+ASRT +E+R I +V
Sbjct: 69  LKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQV 128

Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKG 215
           Y EE    L  D+  DTSG ++  L+ L + +R  D G++E   + DA+AL++AGE + G
Sbjct: 129 YEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWG 188

Query: 216 TDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKP 275
           TD   F TI  TRS   LR+VF KY   S   + + +D E  G++E+ L A+VK   S P
Sbjct: 189 TDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIP 248

Query: 276 AFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDY 335
           A+ AE L+ AMKG GT    LIR+MVSRSEID+ +I+  ++K +  SL   I  +T GDY
Sbjct: 249 AYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDY 308

Query: 336 EKILVALCG 344
           +K L+ LCG
Sbjct: 309 KKALLLLCG 317



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 51/146 (34%), Positives = 85/146 (58%), Gaps = 6/146 (4%)

Query: 47  DVAALHKAIMVK-GVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLE 105
           D  AL +A  +K G DE   I I   R+ +  +++   Y+  +G  ++ET+ +  +G+LE
Sbjct: 175 DAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLE 234

Query: 106 EVVLALLKT----PAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELK 161
           +++LA++K+    PA   A+ L  AMKG GTD+ TLI ++ SR+  ++ +I + +R+   
Sbjct: 235 QLLLAVVKSIRSIPAYL-AETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFA 293

Query: 162 RDLAKDITSDTSGDFRNALLSLAKGD 187
             L   I  DTSGD++ ALL L   D
Sbjct: 294 TSLYSMIKGDTSGDYKKALLLLCGED 319



 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 48/146 (32%), Positives = 76/146 (52%), Gaps = 4/146 (2%)

Query: 201 SDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDI 260
           +DA  L +A  +  GTD     T+LT+RS  Q + +   +      D+   L  EL G  
Sbjct: 19  ADAETLRKA-MKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKF 77

Query: 261 EKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYG 320
           EK + A++K +    A+   +L  A+KG GT  K L  I+ SR+  ++  IK  Y++ YG
Sbjct: 78  EKLIVALMKPSRLYDAY---ELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYG 134

Query: 321 ISLCQAILDETKGDYEKILVALCGGN 346
            SL   ++ +T G Y+++LV L   N
Sbjct: 135 SSLEDDVVGDTSGYYQRMLVVLLQAN 160


>gi|48762937 annexin A10 [Homo sapiens]
          Length = 324

 Score =  219 bits (557), Expect = 4e-57
 Identities = 124/311 (39%), Positives = 184/311 (59%), Gaps = 1/311 (0%)

Query: 36  VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95
           + P P FNP  D   L  A+     D+  +I+ILT+R NAQR  I  AY    G+ L   
Sbjct: 11  IFPAPNFNPIMDAQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGD 70

Query: 96  LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155
           +++ L+ H ++V+  L+  P  +DA EL  AMKG+GTDE+ LIEILASRTN EI  +   
Sbjct: 71  MREQLSDHFKDVMAGLMYPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQMREA 130

Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKG 215
           Y  +   +L +DI S+TSG FR+ L++L +G R E +  +  +A  DA  L+EA +++ G
Sbjct: 131 YCLQYSNNLQEDIYSETSGHFRDTLMNLVQGTREEGY-TDPAMAAQDAMVLWEACQQKTG 189

Query: 216 TDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKP 275
               +   IL  +SY QLR VFQ++   S  DM   ++    G  ++ L AIV C   KP
Sbjct: 190 EHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIVLCVRDKP 249

Query: 276 AFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDY 335
           A+FA +L+ A+   G  +K +IRI+++RSEID+  I+  Y++ YG SL   I +   G Y
Sbjct: 250 AYFAYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERYGKSLFHDIRNFASGHY 309

Query: 336 EKILVALCGGN 346
           +K L+A+C G+
Sbjct: 310 KKALLAICAGD 320



 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 39/153 (25%), Positives = 79/153 (51%), Gaps = 7/153 (4%)

Query: 45  SSDVAALHKAIMVKGVDEATIID-ILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGH 103
           + D   L +A   K  +  T++  IL  ++  Q + +   +   +G+ + + + +   G+
Sbjct: 174 AQDAMVLWEACQQKTGEHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGY 233

Query: 104 LEEVVLALL----KTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREE 159
            +E+++A++      PA F A  L +A+   G    T+I IL +R+  ++  I + Y+E 
Sbjct: 234 FQELLVAIVLCVRDKPAYF-AYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKER 292

Query: 160 LKRDLAKDITSDTSGDFRNALLSLAKGDRSEDF 192
             + L  DI +  SG ++ ALL++  GD +ED+
Sbjct: 293 YGKSLFHDIRNFASGHYKKALLAICAGD-AEDY 324


>gi|145864465 annexin A9 [Homo sapiens]
          Length = 345

 Score =  201 bits (512), Expect = 6e-52
 Identities = 118/320 (36%), Positives = 188/320 (58%), Gaps = 6/320 (1%)

Query: 26  KSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYL 85
           K++  G    +  +  F+   D   L +AI  +GVD + I+D+LT R+  QRQ I   + 
Sbjct: 25  KTAAWGTLGTLRTFLNFSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQ 84

Query: 86  QETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRT 145
           + T + L ++L+ AL+G+LE +V+ALL+  AQFDA ELR A+K   +  D  IEILA+RT
Sbjct: 85  ERTQQDLMKSLQAALSGNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRT 144

Query: 146 NKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFG-VNEDLADSDAR 204
             ++++   VY+   + +   DITS+TSG  ++ LL+LAKG R    G ++ +LA+ D +
Sbjct: 145 PPQLQECLAVYKHNFQVEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAEQDVQ 204

Query: 205 ALYEA-GERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKC 263
           AL  A G  R+ T V VF    T R+   L RVF +Y + +  ++ + +     GD +  
Sbjct: 205 ALQRAEGPSREETWVPVF----TQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVA 260

Query: 264 LTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISL 323
           L  +     + P +FA+KLHQA++     ++ LIRI++SR E D+  I+A ++K +G SL
Sbjct: 261 LLGLASVIKNTPLYFADKLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSL 320

Query: 324 CQAILDETKGDYEKILVALC 343
             ++ D  KGD +  L+ALC
Sbjct: 321 YSSLQDAVKGDCQSALLALC 340



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 43/164 (26%), Positives = 76/164 (46%), Gaps = 7/164 (4%)

Query: 28  SKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVD-EATIIDILTKRNNAQRQQIKAAYLQ 86
           +KGG  S            DV AL +A   +G   E T + + T+RN     ++   Y +
Sbjct: 183 AKGGRDSYSGIIDYNLAEQDVQALQRA---EGPSREETWVPVFTQRNPEHLIRVFDQYQR 239

Query: 87  ETGKPLDETLKKALTGHLEEVVLAL---LKTPAQFDADELRAAMKGLGTDEDTLIEILAS 143
            TG+ L+E ++    G  +  +L L   +K    + AD+L  A++    +   LI IL S
Sbjct: 240 STGQELEEAVQNRFHGDAQVALLGLASVIKNTPLYFADKLHQALQETEPNYQVLIRILIS 299

Query: 144 RTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGD 187
           R   ++  I   +R++  + L   +     GD ++ALL+L + +
Sbjct: 300 RCETDLLSIRAEFRKKFGKSLYSSLQDAVKGDCQSALLALCRAE 343


>gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo
           sapiens]
          Length = 112

 Score = 95.1 bits (235), Expect = 8e-20
 Identities = 49/108 (45%), Positives = 69/108 (63%)

Query: 221 FNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAE 280
           F TIL TRS   L RVF++Y K +   +   +  E  G +E+ +  +VKC  +  ++FAE
Sbjct: 3   FITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAE 62

Query: 281 KLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAIL 328
           +L+ AMKG GTR   LIR +VSRSEID+N IK  ++KMYG +L   I+
Sbjct: 63  RLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIM 110



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 29/106 (27%), Positives = 53/106 (50%), Gaps = 3/106 (2%)

Query: 66  IDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQ---FDADE 122
           I IL  R+     ++   Y +   K +++++K    G LEE +L ++K       + A+ 
Sbjct: 4   ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAER 63

Query: 123 LRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDI 168
           L  AMKG GT + TLI  + SR+  ++  I   +++   + L+  I
Sbjct: 64  LYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109


>gi|188497635 cell division cycle associated 7-like isoform 2 [Homo
           sapiens]
          Length = 420

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%)

Query: 127 MKGLGTDEDT-LIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAK 185
           M+ L ++E     + L S   +++R  ++ + EEL+R   +D  S+T  DF     S   
Sbjct: 1   METLSSEESCDSFDSLESGKQQDVRFHSKYFTEELRRIFIEDTDSETE-DFAGFTQSDLN 59

Query: 186 GDRS-EDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTK 242
           G  + E   V  DL+D    +L    E  +  D        + RS   LR  FQ  TK
Sbjct: 60  GKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTK 117


>gi|31542537 cell division cycle associated 7-like isoform 1 [Homo
           sapiens]
          Length = 454

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%)

Query: 127 MKGLGTDEDT-LIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAK 185
           M+ L ++E     + L S   +++R  ++ + EEL+R   +D  S+T  DF     S   
Sbjct: 35  METLSSEESCDSFDSLESGKQQDVRFHSKYFTEELRRIFIEDTDSETE-DFAGFTQSDLN 93

Query: 186 GDRS-EDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTK 242
           G  + E   V  DL+D    +L    E  +  D        + RS   LR  FQ  TK
Sbjct: 94  GKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTK 151


>gi|148539855 epidermal growth factor receptor pathway substrate
           8-like protein 1 isoform b [Homo sapiens]
          Length = 596

 Score = 30.4 bits (67), Expect = 2.4
 Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 11/103 (10%)

Query: 14  IENEEQEYVQTVKSSKGGPGSAV----SPYPTFNPSSDVAALHKAIMVKGVDEATI--ID 67
           I NEE +    +   + GP  AV    +P P  +P SD + +   +  KG    T+  + 
Sbjct: 473 IVNEELQ--ARLAQGRSGPSRAVPGPRAPEPQLSPGSDASEVRAWLQAKGFSSGTVDALG 530

Query: 68  ILTKRN--NAQRQQIKAAYLQETGKPLDE-TLKKALTGHLEEV 107
           +LT     + Q+++++A   +E  +   + T++++L    E+V
Sbjct: 531 VLTGAQLFSLQKEELRAVSPEEGARVYSQVTVQRSLLEDKEKV 573


>gi|148539853 epidermal growth factor receptor pathway substrate
           8-like protein 1 isoform a [Homo sapiens]
          Length = 723

 Score = 30.4 bits (67), Expect = 2.4
 Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 11/103 (10%)

Query: 14  IENEEQEYVQTVKSSKGGPGSAV----SPYPTFNPSSDVAALHKAIMVKGVDEATI--ID 67
           I NEE +    +   + GP  AV    +P P  +P SD + +   +  KG    T+  + 
Sbjct: 600 IVNEELQ--ARLAQGRSGPSRAVPGPRAPEPQLSPGSDASEVRAWLQAKGFSSGTVDALG 657

Query: 68  ILTKRN--NAQRQQIKAAYLQETGKPLDE-TLKKALTGHLEEV 107
           +LT     + Q+++++A   +E  +   + T++++L    E+V
Sbjct: 658 VLTGAQLFSLQKEELRAVSPEEGARVYSQVTVQRSLLEDKEKV 700


>gi|170650672 Leber congenital amaurosis 5 [Homo sapiens]
          Length = 697

 Score = 29.6 bits (65), Expect = 4.1
 Identities = 37/136 (27%), Positives = 56/136 (41%), Gaps = 7/136 (5%)

Query: 128 KGLGTDEDTLIEI--LASRTNKEIRDINRVYR--EELKRDLAKDITSDTSGDFRN--ALL 181
           K L   ED   EI  L  R N EI  +    R  +E +R   K +    S  FR   +L 
Sbjct: 145 KALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQ 204

Query: 182 SLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYT 241
            L +   +      +DLA     A  +  +  +       N  L+T S+ Q + + ++  
Sbjct: 205 KLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSF-QRQLLAERKR 263

Query: 242 KYSKHDMNKVLDLELK 257
            Y  HD NKVL  E++
Sbjct: 264 AYEAHDENKVLQKEVQ 279


>gi|170650670 Leber congenital amaurosis 5 [Homo sapiens]
          Length = 697

 Score = 29.6 bits (65), Expect = 4.1
 Identities = 37/136 (27%), Positives = 56/136 (41%), Gaps = 7/136 (5%)

Query: 128 KGLGTDEDTLIEI--LASRTNKEIRDINRVYR--EELKRDLAKDITSDTSGDFRN--ALL 181
           K L   ED   EI  L  R N EI  +    R  +E +R   K +    S  FR   +L 
Sbjct: 145 KALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQ 204

Query: 182 SLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYT 241
            L +   +      +DLA     A  +  +  +       N  L+T S+ Q + + ++  
Sbjct: 205 KLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSF-QRQLLAERKR 263

Query: 242 KYSKHDMNKVLDLELK 257
            Y  HD NKVL  E++
Sbjct: 264 AYEAHDENKVLQKEVQ 279


>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
           sapiens]
          Length = 631

 Score = 29.3 bits (64), Expect = 5.4
 Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 28/163 (17%)

Query: 71  KRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGL 130
           K   A RQ+ +   L+E  + L E L+              L+  A+ D + +R A   L
Sbjct: 417 KEEEAARQRQRIKELEEMQQRLQEALQ--------------LEVKARRDEESVRIAQTRL 462

Query: 131 GTDEDTLIEILASRTNKEIRDINRVY--REELKRDLAKDITSDTSGDFRNALLSLAKGDR 188
             +E+  ++ L     ++ R I R    +EEL++++A+   S          L  A+  +
Sbjct: 463 LEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRS----------LQQAQ-QQ 511

Query: 189 SEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYP 231
            E+   N   AD D  A  +   R+  T+V  +N  +    +P
Sbjct: 512 LEEVRQNRQRADEDVEAA-QRKLRQASTNVKHWNVQMNRLMHP 553


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,857,639
Number of Sequences: 37866
Number of extensions: 481848
Number of successful extensions: 1639
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1405
Number of HSP's gapped (non-prelim): 61
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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