BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4502101 annexin I [Homo sapiens] (346 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4502101 annexin I [Homo sapiens] 678 0.0 gi|4757756 annexin A2 isoform 2 [Homo sapiens] 336 2e-92 gi|50845386 annexin A2 isoform 2 [Homo sapiens] 336 2e-92 gi|50845388 annexin A2 isoform 1 [Homo sapiens] 336 2e-92 gi|209862831 annexin A2 isoform 2 [Homo sapiens] 336 2e-92 gi|4557317 annexin A11 [Homo sapiens] 294 9e-80 gi|22165433 annexin A11 [Homo sapiens] 294 9e-80 gi|22165431 annexin A11 [Homo sapiens] 294 9e-80 gi|4826643 annexin A3 [Homo sapiens] 294 9e-80 gi|4809279 annexin VII isoform 2 [Homo sapiens] 278 5e-75 gi|4502111 annexin VII isoform 1 [Homo sapiens] 278 5e-75 gi|71773415 annexin VI isoform 2 [Homo sapiens] 271 8e-73 gi|4502105 annexin IV [Homo sapiens] 270 1e-72 gi|71773329 annexin VI isoform 1 [Homo sapiens] 268 7e-72 gi|91823262 annexin A8 [Homo sapiens] 259 2e-69 gi|91807122 annexin A8L2 [Homo sapiens] 258 5e-69 gi|149588958 annexin A8-like 1 [Homo sapiens] 258 5e-69 gi|51896029 annexin A13 isoform b [Homo sapiens] 258 5e-69 gi|51895795 annexin A13 isoform a [Homo sapiens] 256 2e-68 gi|4502107 annexin 5 [Homo sapiens] 256 3e-68 gi|48762937 annexin A10 [Homo sapiens] 219 4e-57 gi|145864465 annexin A9 [Homo sapiens] 201 6e-52 gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo ... 95 8e-20 gi|188497635 cell division cycle associated 7-like isoform 2 [Ho... 31 1.9 gi|31542537 cell division cycle associated 7-like isoform 1 [Hom... 31 1.9 gi|148539855 epidermal growth factor receptor pathway substrate ... 30 2.4 gi|148539853 epidermal growth factor receptor pathway substrate ... 30 2.4 gi|170650672 Leber congenital amaurosis 5 [Homo sapiens] 30 4.1 gi|170650670 Leber congenital amaurosis 5 [Homo sapiens] 30 4.1 gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 29 5.4 >gi|4502101 annexin I [Homo sapiens] Length = 346 Score = 678 bits (1749), Expect = 0.0 Identities = 346/346 (100%), Positives = 346/346 (100%) Query: 1 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGV 60 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGV Sbjct: 1 MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGV 60 Query: 61 DEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDA 120 DEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDA Sbjct: 61 DEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDA 120 Query: 121 DELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNAL 180 DELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNAL Sbjct: 121 DELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNAL 180 Query: 181 LSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKY 240 LSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKY Sbjct: 181 LSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKY 240 Query: 241 TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM 300 TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM Sbjct: 241 TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM 300 Query: 301 VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346 VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN Sbjct: 301 VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346 >gi|4757756 annexin A2 isoform 2 [Homo sapiens] Length = 339 Score = 336 bits (861), Expect = 2e-92 Identities = 172/313 (54%), Positives = 228/313 (72%), Gaps = 1/313 (0%) Query: 35 AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94 +V Y F+ D + AI KGVDE TI++ILT R+NAQRQ I AY + T K L Sbjct: 26 SVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELAS 85 Query: 95 TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154 LK AL+GHLE V+L LLKTPAQ+DA EL+A+MKGLGTDED+LIEI+ SRTN+E+++INR Sbjct: 86 ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 145 Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERR 213 VY+E K DL KDI SDTSGDFR +++LAKG R+ED V + +L D DAR LY+AG +R Sbjct: 146 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKR 205 Query: 214 KGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273 KGTDV + +I+T RS P L++VF +Y YS +DM + + E+KGD+E +V+C + Sbjct: 206 KGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQN 265 Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333 KP +FA++L+ +MKG GTR K LIRIMVSRSE+DM I++ +++ YG SL I +TKG Sbjct: 266 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 325 Query: 334 DYEKILVALCGGN 346 DY+K L+ LCGG+ Sbjct: 326 DYQKALLYLCGGD 338 >gi|50845386 annexin A2 isoform 2 [Homo sapiens] Length = 339 Score = 336 bits (861), Expect = 2e-92 Identities = 172/313 (54%), Positives = 228/313 (72%), Gaps = 1/313 (0%) Query: 35 AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94 +V Y F+ D + AI KGVDE TI++ILT R+NAQRQ I AY + T K L Sbjct: 26 SVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELAS 85 Query: 95 TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154 LK AL+GHLE V+L LLKTPAQ+DA EL+A+MKGLGTDED+LIEI+ SRTN+E+++INR Sbjct: 86 ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 145 Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERR 213 VY+E K DL KDI SDTSGDFR +++LAKG R+ED V + +L D DAR LY+AG +R Sbjct: 146 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKR 205 Query: 214 KGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273 KGTDV + +I+T RS P L++VF +Y YS +DM + + E+KGD+E +V+C + Sbjct: 206 KGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQN 265 Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333 KP +FA++L+ +MKG GTR K LIRIMVSRSE+DM I++ +++ YG SL I +TKG Sbjct: 266 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 325 Query: 334 DYEKILVALCGGN 346 DY+K L+ LCGG+ Sbjct: 326 DYQKALLYLCGGD 338 >gi|50845388 annexin A2 isoform 1 [Homo sapiens] Length = 357 Score = 336 bits (861), Expect = 2e-92 Identities = 172/313 (54%), Positives = 228/313 (72%), Gaps = 1/313 (0%) Query: 35 AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94 +V Y F+ D + AI KGVDE TI++ILT R+NAQRQ I AY + T K L Sbjct: 44 SVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELAS 103 Query: 95 TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154 LK AL+GHLE V+L LLKTPAQ+DA EL+A+MKGLGTDED+LIEI+ SRTN+E+++INR Sbjct: 104 ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 163 Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERR 213 VY+E K DL KDI SDTSGDFR +++LAKG R+ED V + +L D DAR LY+AG +R Sbjct: 164 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKR 223 Query: 214 KGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273 KGTDV + +I+T RS P L++VF +Y YS +DM + + E+KGD+E +V+C + Sbjct: 224 KGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQN 283 Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333 KP +FA++L+ +MKG GTR K LIRIMVSRSE+DM I++ +++ YG SL I +TKG Sbjct: 284 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 343 Query: 334 DYEKILVALCGGN 346 DY+K L+ LCGG+ Sbjct: 344 DYQKALLYLCGGD 356 >gi|209862831 annexin A2 isoform 2 [Homo sapiens] Length = 339 Score = 336 bits (861), Expect = 2e-92 Identities = 172/313 (54%), Positives = 228/313 (72%), Gaps = 1/313 (0%) Query: 35 AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94 +V Y F+ D + AI KGVDE TI++ILT R+NAQRQ I AY + T K L Sbjct: 26 SVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELAS 85 Query: 95 TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154 LK AL+GHLE V+L LLKTPAQ+DA EL+A+MKGLGTDED+LIEI+ SRTN+E+++INR Sbjct: 86 ALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINR 145 Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGV-NEDLADSDARALYEAGERR 213 VY+E K DL KDI SDTSGDFR +++LAKG R+ED V + +L D DAR LY+AG +R Sbjct: 146 VYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARDLYDAGVKR 205 Query: 214 KGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273 KGTDV + +I+T RS P L++VF +Y YS +DM + + E+KGD+E +V+C + Sbjct: 206 KGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQN 265 Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333 KP +FA++L+ +MKG GTR K LIRIMVSRSE+DM I++ +++ YG SL I +TKG Sbjct: 266 KPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYYIQQDTKG 325 Query: 334 DYEKILVALCGGN 346 DY+K L+ LCGG+ Sbjct: 326 DYQKALLYLCGGD 338 >gi|4557317 annexin A11 [Homo sapiens] Length = 505 Score = 294 bits (752), Expect = 9e-80 Identities = 153/322 (47%), Positives = 214/322 (66%) Query: 25 VKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAY 84 V ++ G ++ P F+P D L KA+ G DE IID L R+N QRQQI ++ Sbjct: 183 VPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSF 242 Query: 85 LQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASR 144 GK L + LK L+G+ E+ +LAL+KTP FD E++ A+KG+GTDE LIEILASR Sbjct: 243 KTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASR 302 Query: 145 TNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDAR 204 +N+ IR++NR Y+ E K+ L + I SDTSG F+ L+SL++G+R E V+ LA DA+ Sbjct: 303 SNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQ 362 Query: 205 ALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCL 264 LY AGE R GTD + FN +L +RS L VF +Y + + D+ K + E+ GD+E+ + Sbjct: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422 Query: 265 TAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLC 324 A+VKC + PAFFAE+L++AM+G GT+ + LIRIMVSRSE D+ DI++ Y++MYG SL Sbjct: 423 LAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLY 482 Query: 325 QAILDETKGDYEKILVALCGGN 346 I +T GDY KIL+ +CGGN Sbjct: 483 HDISGDTSGDYRKILLKICGGN 504 >gi|22165433 annexin A11 [Homo sapiens] Length = 505 Score = 294 bits (752), Expect = 9e-80 Identities = 153/322 (47%), Positives = 214/322 (66%) Query: 25 VKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAY 84 V ++ G ++ P F+P D L KA+ G DE IID L R+N QRQQI ++ Sbjct: 183 VPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSF 242 Query: 85 LQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASR 144 GK L + LK L+G+ E+ +LAL+KTP FD E++ A+KG+GTDE LIEILASR Sbjct: 243 KTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASR 302 Query: 145 TNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDAR 204 +N+ IR++NR Y+ E K+ L + I SDTSG F+ L+SL++G+R E V+ LA DA+ Sbjct: 303 SNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQ 362 Query: 205 ALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCL 264 LY AGE R GTD + FN +L +RS L VF +Y + + D+ K + E+ GD+E+ + Sbjct: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422 Query: 265 TAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLC 324 A+VKC + PAFFAE+L++AM+G GT+ + LIRIMVSRSE D+ DI++ Y++MYG SL Sbjct: 423 LAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLY 482 Query: 325 QAILDETKGDYEKILVALCGGN 346 I +T GDY KIL+ +CGGN Sbjct: 483 HDISGDTSGDYRKILLKICGGN 504 >gi|22165431 annexin A11 [Homo sapiens] Length = 505 Score = 294 bits (752), Expect = 9e-80 Identities = 153/322 (47%), Positives = 214/322 (66%) Query: 25 VKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAY 84 V ++ G ++ P F+P D L KA+ G DE IID L R+N QRQQI ++ Sbjct: 183 VPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSF 242 Query: 85 LQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASR 144 GK L + LK L+G+ E+ +LAL+KTP FD E++ A+KG+GTDE LIEILASR Sbjct: 243 KTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASR 302 Query: 145 TNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDAR 204 +N+ IR++NR Y+ E K+ L + I SDTSG F+ L+SL++G+R E V+ LA DA+ Sbjct: 303 SNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQ 362 Query: 205 ALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCL 264 LY AGE R GTD + FN +L +RS L VF +Y + + D+ K + E+ GD+E+ + Sbjct: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422 Query: 265 TAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLC 324 A+VKC + PAFFAE+L++AM+G GT+ + LIRIMVSRSE D+ DI++ Y++MYG SL Sbjct: 423 LAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLY 482 Query: 325 QAILDETKGDYEKILVALCGGN 346 I +T GDY KIL+ +CGGN Sbjct: 483 HDISGDTSGDYRKILLKICGGN 504 >gi|4826643 annexin A3 [Homo sapiens] Length = 323 Score = 294 bits (752), Expect = 9e-80 Identities = 157/316 (49%), Positives = 207/316 (65%) Query: 31 GPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGK 90 G V YP F+PS D A+ KAI G DE +I ILT+R+NAQRQ I Y GK Sbjct: 7 GHRGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGK 66 Query: 91 PLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIR 150 L + LK L+GH E +++AL+ PA FDA +L+ +MKG GT+ED LIEIL +RT+++++ Sbjct: 67 ELKDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMK 126 Query: 151 DINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAG 210 DI++ Y K+ L DI+S+TSGDFR ALL+LA G R E V+E LA DA+ LY+AG Sbjct: 127 DISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAG 186 Query: 211 ERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKC 270 E R GTD + F IL RS+PQL+ F +Y S+ D+ + EL G E L AIV C Sbjct: 187 ENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNC 246 Query: 271 ATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDE 330 + PAF AE+LH+A+KG+GT L RIMVSRSEID+ DI+ ++K YG SL AI + Sbjct: 247 VRNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSD 306 Query: 331 TKGDYEKILVALCGGN 346 T GDYE L+ +CGG+ Sbjct: 307 TSGDYEITLLKICGGD 322 >gi|4809279 annexin VII isoform 2 [Homo sapiens] Length = 488 Score = 278 bits (711), Expect = 5e-75 Identities = 143/309 (46%), Positives = 200/309 (64%) Query: 36 VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95 + P F+ D L KA+ G DE I+D++ R+N QRQ+IKAA+ GK L + Sbjct: 179 IRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKD 238 Query: 96 LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155 LK L+G++EE++LAL P +DA LR AM+G GT E LIEIL +RTN+EIR+I R Sbjct: 239 LKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRC 298 Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKG 215 Y+ E RDL KDI SDTSG F L+S+ +G+R E+ +N +A DA+ LY+AGE R G Sbjct: 299 YQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLG 358 Query: 216 TDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKP 275 TD + FN IL TRS+PQLR + Y++ + D+ + E G +E L I++CA ++P Sbjct: 359 TDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRP 418 Query: 276 AFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDY 335 AFFAE+L+ AMKG GT L+RI+V+RSEID+ IK + +MY +L I +T GDY Sbjct: 419 AFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDY 478 Query: 336 EKILVALCG 344 ++L+A+ G Sbjct: 479 RRLLLAIVG 487 Score = 70.1 bits (170), Expect = 3e-12 Identities = 43/133 (32%), Positives = 74/133 (55%), Gaps = 5/133 (3%) Query: 215 GTDVNVFNTILTTRSYPQLRRVFQKY-TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273 GTD ++ RS Q +++ + T Y K D+ K L EL G++E+ + A+ T Sbjct: 202 GTDEQAIVDVVANRSNDQRQKIKAAFKTSYGK-DLIKDLKSELSGNMEELILALFMPPTY 260 Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333 A+ L +AM+G GT+ + LI I+ +R+ ++ +I YQ +G L + I +T G Sbjct: 261 YDAW---SLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSG 317 Query: 334 DYEKILVALCGGN 346 +E++LV++C GN Sbjct: 318 HFERLLVSMCQGN 330 >gi|4502111 annexin VII isoform 1 [Homo sapiens] Length = 466 Score = 278 bits (711), Expect = 5e-75 Identities = 143/309 (46%), Positives = 200/309 (64%) Query: 36 VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95 + P F+ D L KA+ G DE I+D++ R+N QRQ+IKAA+ GK L + Sbjct: 157 IRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKD 216 Query: 96 LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155 LK L+G++EE++LAL P +DA LR AM+G GT E LIEIL +RTN+EIR+I R Sbjct: 217 LKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRC 276 Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKG 215 Y+ E RDL KDI SDTSG F L+S+ +G+R E+ +N +A DA+ LY+AGE R G Sbjct: 277 YQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLG 336 Query: 216 TDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKP 275 TD + FN IL TRS+PQLR + Y++ + D+ + E G +E L I++CA ++P Sbjct: 337 TDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRP 396 Query: 276 AFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDY 335 AFFAE+L+ AMKG GT L+RI+V+RSEID+ IK + +MY +L I +T GDY Sbjct: 397 AFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDY 456 Query: 336 EKILVALCG 344 ++L+A+ G Sbjct: 457 RRLLLAIVG 465 Score = 70.1 bits (170), Expect = 3e-12 Identities = 43/133 (32%), Positives = 74/133 (55%), Gaps = 5/133 (3%) Query: 215 GTDVNVFNTILTTRSYPQLRRVFQKY-TKYSKHDMNKVLDLELKGDIEKCLTAIVKCATS 273 GTD ++ RS Q +++ + T Y K D+ K L EL G++E+ + A+ T Sbjct: 180 GTDEQAIVDVVANRSNDQRQKIKAAFKTSYGK-DLIKDLKSELSGNMEELILALFMPPTY 238 Query: 274 KPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKG 333 A+ L +AM+G GT+ + LI I+ +R+ ++ +I YQ +G L + I +T G Sbjct: 239 YDAW---SLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSG 295 Query: 334 DYEKILVALCGGN 346 +E++LV++C GN Sbjct: 296 HFERLLVSMCQGN 308 >gi|71773415 annexin VI isoform 2 [Homo sapiens] Length = 667 Score = 271 bits (692), Expect = 8e-73 Identities = 148/310 (47%), Positives = 198/310 (63%), Gaps = 1/310 (0%) Query: 36 VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95 V P FNP +D AL KA+ G DE TIIDI+T R+N QRQQI+ + G+ L Sbjct: 357 VRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTD 416 Query: 96 LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155 LK ++G L ++L L+ PA +DA +L+ AM+G GTDE LIEILA+RTN EIR IN Sbjct: 417 LKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEA 476 Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKG 215 Y+E+ + L ++SDTSG FR L+SLA G R E+ G N D A DA+ + + K Sbjct: 477 YKEDYHKSLEDALSSDTSGHFRRILISLATGHR-EEGGENLDQAREDAQEIADTPSGDKT 535 Query: 216 TDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKP 275 + F TIL TRSYP LRRVFQ++ K + +D+ + E+ GD+ AIV+ +KP Sbjct: 536 SLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKP 595 Query: 276 AFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDY 335 FFA+KL+++MKG GT K L RIMVSRSEID+ +I+ + + Y SL QAI +T GD+ Sbjct: 596 LFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDF 655 Query: 336 EKILVALCGG 345 K L+ALCGG Sbjct: 656 LKALLALCGG 665 Score = 262 bits (670), Expect = 3e-70 Identities = 141/312 (45%), Positives = 197/312 (63%) Query: 35 AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94 ++ +P F+P+ D AL+ A+ G D+ I+DI+T R+N QRQ++ +Y GK L Sbjct: 13 SIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIA 72 Query: 95 TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154 LK LTG E +++ L++ PA DA E++ A+ G+GTDE LIEILASRTN+++ + Sbjct: 73 DLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVA 132 Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRK 214 Y++ +RDL DI DTSG F+ L+ L +G R ED V+EDL D + LYEAGE + Sbjct: 133 AYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKW 192 Query: 215 GTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSK 274 GTD F IL RS LR VF +Y K + + + EL GD EK + A+VKC S Sbjct: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRST 252 Query: 275 PAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGD 334 P +FAE+L +AMKG+GTR LIRIMVSRSE+DM DI+ ++ Y SL I ++T G+ Sbjct: 253 PEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGE 312 Query: 335 YEKILVALCGGN 346 Y+K L+ L GG+ Sbjct: 313 YKKTLLKLSGGD 324 Score = 150 bits (378), Expect = 2e-36 Identities = 108/335 (32%), Positives = 181/335 (54%), Gaps = 41/335 (12%) Query: 47 DVAALHKAIMVK-GVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLE 105 DV L++A +K G DEA I IL R+ + + YL+ TGKP++ +++ L+G E Sbjct: 180 DVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFE 239 Query: 106 EVVLALLK----TPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELK 161 +++LA++K TP F A+ L AMKGLGT ++TLI I+ SR+ ++ DI ++R + + Sbjct: 240 KLMLAVVKCIRSTPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYE 298 Query: 162 RDLAKDITSDTSGDFRNALLSLAKGD-------------------------RSEDFGV-- 194 + L I +DTSG+++ LL L+ GD R E G Sbjct: 299 KSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVR 358 Query: 195 --NEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVL 252 N+ D+DA+AL +A + GTD + I+T RS Q +++ Q + + D+ L Sbjct: 359 PANDFNPDADAKALRKA-MKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDL 417 Query: 253 DLELKGDIEKCLTAIVKCATSKPAFF-AEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDI 311 E+ GD+ + + ++ PA + A++L +AM+G GT KALI I+ +R+ ++ I Sbjct: 418 KSEISGDLARLILGLMM----PPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473 Query: 312 KAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346 Y++ Y SL A+ +T G + +IL++L G+ Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGH 508 Score = 77.0 bits (188), Expect = 2e-14 Identities = 43/129 (33%), Positives = 74/129 (57%), Gaps = 3/129 (2%) Query: 62 EATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALL---KTPAQF 118 E + IL R+ +++ +++ T ++ T+KK ++G + + +A++ K F Sbjct: 538 ETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLF 597 Query: 119 DADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRN 178 AD+L +MKG GTDE TL I+ SR+ ++ +I R + E+ + L + I DTSGDF Sbjct: 598 FADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLK 657 Query: 179 ALLSLAKGD 187 ALL+L G+ Sbjct: 658 ALLALCGGE 666 >gi|4502105 annexin IV [Homo sapiens] Length = 321 Score = 270 bits (691), Expect = 1e-72 Identities = 147/320 (45%), Positives = 204/320 (63%), Gaps = 3/320 (0%) Query: 27 SSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQ 86 ++KGG A S FN D L KA+ G DE II +L RN AQRQ+I+ AY Sbjct: 4 ATKGGTVKAASG---FNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKS 60 Query: 87 ETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTN 146 G+ L + LK L+G+ E+V++ ++ +D ELR AMKG GTDE LIEILASRT Sbjct: 61 TIGRDLIDDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTP 120 Query: 147 KEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARAL 206 +EIR I++ Y+++ R L DI SDTS F+ L+SL+ G R E +++ L DA+ L Sbjct: 121 EEIRRISQTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDL 180 Query: 207 YEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTA 266 YEAGE++ GTD F T+L +R+ L VF +Y + S+ D+ + + E G E L A Sbjct: 181 YEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLA 240 Query: 267 IVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQA 326 IVKC +K A+FAEKL+++MKG+GT LIR+MVSR+EIDM DI+A ++++YG SL Sbjct: 241 IVKCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSF 300 Query: 327 ILDETKGDYEKILVALCGGN 346 I +T GDY K+L+ LCGG+ Sbjct: 301 IKGDTSGDYRKVLLVLCGGD 320 >gi|71773329 annexin VI isoform 1 [Homo sapiens] Length = 673 Score = 268 bits (684), Expect = 7e-72 Identities = 149/316 (47%), Positives = 200/316 (63%), Gaps = 7/316 (2%) Query: 36 VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95 V P FNP +D AL KA+ G DE TIIDI+T R+N QRQQI+ + G+ L Sbjct: 357 VRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTD 416 Query: 96 LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155 LK ++G L ++L L+ PA +DA +L+ AM+G GTDE LIEILA+RTN EIR IN Sbjct: 417 LKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEA 476 Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARA---LYEAGER 212 Y+E+ + L ++SDTSG FR L+SLA G R E+ G N D A DA+ + E + Sbjct: 477 YKEDYHKSLEDALSSDTSGHFRRILISLATGHR-EEGGENLDQAREDAQVAAEILEIADT 535 Query: 213 RKGTDVNV---FNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVK 269 G ++ F TIL TRSYP LRRVFQ++ K + +D+ + E+ GD+ AIV+ Sbjct: 536 PSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQ 595 Query: 270 CATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILD 329 +KP FFA+KL+++MKG GT K L RIMVSRSEID+ +I+ + + Y SL QAI Sbjct: 596 SVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEG 655 Query: 330 ETKGDYEKILVALCGG 345 +T GD+ K L+ALCGG Sbjct: 656 DTSGDFLKALLALCGG 671 Score = 262 bits (670), Expect = 3e-70 Identities = 141/312 (45%), Positives = 197/312 (63%) Query: 35 AVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDE 94 ++ +P F+P+ D AL+ A+ G D+ I+DI+T R+N QRQ++ +Y GK L Sbjct: 13 SIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIA 72 Query: 95 TLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINR 154 LK LTG E +++ L++ PA DA E++ A+ G+GTDE LIEILASRTN+++ + Sbjct: 73 DLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVA 132 Query: 155 VYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRK 214 Y++ +RDL DI DTSG F+ L+ L +G R ED V+EDL D + LYEAGE + Sbjct: 133 AYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKW 192 Query: 215 GTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSK 274 GTD F IL RS LR VF +Y K + + + EL GD EK + A+VKC S Sbjct: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRST 252 Query: 275 PAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGD 334 P +FAE+L +AMKG+GTR LIRIMVSRSE+DM DI+ ++ Y SL I ++T G+ Sbjct: 253 PEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGE 312 Query: 335 YEKILVALCGGN 346 Y+K L+ L GG+ Sbjct: 313 YKKTLLKLSGGD 324 Score = 150 bits (378), Expect = 2e-36 Identities = 108/335 (32%), Positives = 181/335 (54%), Gaps = 41/335 (12%) Query: 47 DVAALHKAIMVK-GVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLE 105 DV L++A +K G DEA I IL R+ + + YL+ TGKP++ +++ L+G E Sbjct: 180 DVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFE 239 Query: 106 EVVLALLK----TPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELK 161 +++LA++K TP F A+ L AMKGLGT ++TLI I+ SR+ ++ DI ++R + + Sbjct: 240 KLMLAVVKCIRSTPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYE 298 Query: 162 RDLAKDITSDTSGDFRNALLSLAKGD-------------------------RSEDFGV-- 194 + L I +DTSG+++ LL L+ GD R E G Sbjct: 299 KSLYSMIKNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVR 358 Query: 195 --NEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVL 252 N+ D+DA+AL +A + GTD + I+T RS Q +++ Q + + D+ L Sbjct: 359 PANDFNPDADAKALRKA-MKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDL 417 Query: 253 DLELKGDIEKCLTAIVKCATSKPAFF-AEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDI 311 E+ GD+ + + ++ PA + A++L +AM+G GT KALI I+ +R+ ++ I Sbjct: 418 KSEISGDLARLILGLMM----PPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473 Query: 312 KAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346 Y++ Y SL A+ +T G + +IL++L G+ Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGH 508 Score = 77.0 bits (188), Expect = 2e-14 Identities = 43/129 (33%), Positives = 74/129 (57%), Gaps = 3/129 (2%) Query: 62 EATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALL---KTPAQF 118 E + IL R+ +++ +++ T ++ T+KK ++G + + +A++ K F Sbjct: 544 ETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLF 603 Query: 119 DADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRN 178 AD+L +MKG GTDE TL I+ SR+ ++ +I R + E+ + L + I DTSGDF Sbjct: 604 FADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLK 663 Query: 179 ALLSLAKGD 187 ALL+L G+ Sbjct: 664 ALLALCGGE 672 >gi|91823262 annexin A8 [Homo sapiens] Length = 327 Score = 259 bits (663), Expect = 2e-69 Identities = 149/337 (44%), Positives = 207/337 (61%), Gaps = 13/337 (3%) Query: 11 AWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILT 70 AW+ EQE V TVKSS FNP D L+KA+ G +E IID+LT Sbjct: 2 AWWKSWIEQEGV-TVKSSSH-----------FNPDPDAETLYKAMKGIGTNEQAIIDVLT 49 Query: 71 KRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGL 130 KR+N QRQQI ++ + GK L ETLK L+G E +++AL+ P +++A EL AMKGL Sbjct: 50 KRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGL 109 Query: 131 GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSE 190 GT E +IEILASRT ++R+I + Y E+ L +DI +DTSG L+ L +G R + Sbjct: 110 GTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDD 169 Query: 191 -DFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMN 249 V+ LA DA+ LY AGE+ +GTD F TIL TRS L RVF++Y K + + Sbjct: 170 VSSFVDPGLALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIE 229 Query: 250 KVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMN 309 + E G +E+ + +VKC + ++FAE+L+ AMKG GTR LIR +VSRSEID+N Sbjct: 230 DSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLN 289 Query: 310 DIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346 IK ++KMYG +L I+++T GDY+ L++L G + Sbjct: 290 LIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSD 326 >gi|91807122 annexin A8L2 [Homo sapiens] Length = 327 Score = 258 bits (659), Expect = 5e-69 Identities = 149/337 (44%), Positives = 206/337 (61%), Gaps = 13/337 (3%) Query: 11 AWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILT 70 AW+ EQE V TVKSS FNP D L+KA+ G +E IID+LT Sbjct: 2 AWWKAWIEQEGV-TVKSSSH-----------FNPDPDAETLYKAMKGIGTNEQAIIDVLT 49 Query: 71 KRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGL 130 KR+N QRQQI ++ + GK L ETLK L+G E +++AL+ P +++A EL AMKGL Sbjct: 50 KRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGL 109 Query: 131 GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSE 190 GT E +IEILASRT ++R+I + Y E+ L +DI +DTSG L+ L +G R + Sbjct: 110 GTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDD 169 Query: 191 -DFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMN 249 V+ LA DA+ LY AGE +GTD F TIL TRS L RVF++Y K + + Sbjct: 170 VSSFVDPALALQDAQDLYAAGENIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIE 229 Query: 250 KVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMN 309 + E G +E+ + +VKC + ++FAE+L+ AMKG GTR LIR +VSRSEID+N Sbjct: 230 DSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLN 289 Query: 310 DIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346 IK ++KMYG +L I+++T GDY+ L++L G + Sbjct: 290 LIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSD 326 >gi|149588958 annexin A8-like 1 [Homo sapiens] Length = 327 Score = 258 bits (659), Expect = 5e-69 Identities = 148/337 (43%), Positives = 207/337 (61%), Gaps = 13/337 (3%) Query: 11 AWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILT 70 AW+ EQE V TVKSS FNP D L++A+ G +E IID+LT Sbjct: 2 AWWKSWIEQEGV-TVKSSSH-----------FNPDPDAETLYQAMKGIGTNEQAIIDVLT 49 Query: 71 KRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGL 130 KR+N QRQQI ++ + GK L ETLK L+G E +++AL+ P +++A EL AMKGL Sbjct: 50 KRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGL 109 Query: 131 GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSE 190 GT E +IEILASRT ++R+I + Y E+ L +DI +DTSG L+ L +G R + Sbjct: 110 GTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDD 169 Query: 191 -DFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMN 249 V+ LA DA+ LY AGE+ +GTD F TIL TRS L RVF++Y K + + Sbjct: 170 VSSFVDPGLALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIE 229 Query: 250 KVLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMN 309 + E G +E+ + +VKC + ++FAE+L+ AMKG GTR LIR +VSRSEID+N Sbjct: 230 DSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLN 289 Query: 310 DIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346 IK ++KMYG +L I+++T GDY+ L++L G + Sbjct: 290 LIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSD 326 >gi|51896029 annexin A13 isoform b [Homo sapiens] Length = 357 Score = 258 bits (659), Expect = 5e-69 Identities = 139/311 (44%), Positives = 195/311 (62%), Gaps = 1/311 (0%) Query: 32 PGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKP 91 P A SP F+ D L+KA G +EA II+IL+ R + +RQQIK Y GK Sbjct: 46 PAKASSPQG-FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKE 104 Query: 92 LDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRD 151 L+E LK L+G+ E+ LALL P+++ A +L+ AMKGLGTDE LIE+L +RTNKEI Sbjct: 105 LEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIA 164 Query: 152 INRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGE 211 I Y+ R L D+ DTSG+ + L+SL + +R+E V++DLA DA+ LY+AGE Sbjct: 165 IKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGE 224 Query: 212 RRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCA 271 R GTD FN +L RSY QLR FQ Y D+ + ++ E GD++K +V+CA Sbjct: 225 GRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCA 284 Query: 272 TSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDET 331 +FAE+L+++MKG GT + LIRI+V+R+E+D+ IKA +Q+ Y SL + +T Sbjct: 285 QDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDT 344 Query: 332 KGDYEKILVAL 342 GD+ K+LVAL Sbjct: 345 SGDFRKLLVAL 355 Score = 86.7 bits (213), Expect = 3e-17 Identities = 72/263 (27%), Positives = 128/263 (48%), Gaps = 22/263 (8%) Query: 19 QEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAA-LHKAIMVKGVDEATIIDILTKRNNAQR 77 +E + +KS G + PS A L KA+ G DE+ +I++L R N + Sbjct: 103 KELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEI 162 Query: 78 QQIKAAYLQETGKPLDETLKKALTGHLEEVVLALL-----------KTPAQFDADELRAA 126 IK AY + + L+ +K +G+L++++++LL K A DA +L A Sbjct: 163 IAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDA 222 Query: 127 MKGL-GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAK 185 +G GTDE E+LA R+ K++R + Y+ + +D+ + I +TSGD + A L+L + Sbjct: 223 GEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVR 282 Query: 186 GDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSK 245 +D D A LY++ + GTD I+ TR+ L+ + K+ + + Sbjct: 283 --------CAQDCEDYFAERLYKS-MKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 333 Query: 246 HDMNKVLDLELKGDIEKCLTAIV 268 ++ ++ + GD K L A++ Sbjct: 334 KSLSDMVRSDTSGDFRKLLVALL 356 Score = 70.9 bits (172), Expect = 2e-12 Identities = 51/164 (31%), Positives = 88/164 (53%), Gaps = 11/164 (6%) Query: 184 AKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKY 243 AK + F V D DA+ L +A + GT+ IL+ R+ + +++ QKY Sbjct: 47 AKASSPQGFDV-----DRDAKKLNKAC-KGMGTNEAAIIEILSGRTSDERQQIKQKYKAT 100 Query: 244 SKHDMNKVLDLELKGDIEKCLTAIVKCATSKPA-FFAEKLHQAMKGVGTRHKALIRIMVS 302 ++ +VL EL G+ EK A++ +P+ + A +L +AMKG+GT LI ++ + Sbjct: 101 YGKELEEVLKSELSGNFEKTALALL----DRPSEYAARQLQKAMKGLGTDESVLIEVLCT 156 Query: 303 RSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346 R+ ++ IK YQ+++ SL + +T G+ +KILV+L N Sbjct: 157 RTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 200 >gi|51895795 annexin A13 isoform a [Homo sapiens] Length = 316 Score = 256 bits (654), Expect = 2e-68 Identities = 135/301 (44%), Positives = 191/301 (63%) Query: 42 FNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALT 101 F+ D L+KA G +EA II+IL+ R + +RQQIK Y GK L+E LK L+ Sbjct: 14 FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 73 Query: 102 GHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELK 161 G+ E+ LALL P+++ A +L+ AMKGLGTDE LIE+L +RTNKEI I Y+ Sbjct: 74 GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 133 Query: 162 RDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVF 221 R L D+ DTSG+ + L+SL + +R+E V++DLA DA+ LY+AGE R GTD F Sbjct: 134 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 193 Query: 222 NTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAEK 281 N +L RSY QLR FQ Y D+ + ++ E GD++K +V+CA +FAE+ Sbjct: 194 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 253 Query: 282 LHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVA 341 L+++MKG GT + LIRI+V+R+E+D+ IKA +Q+ Y SL + +T GD+ K+LVA Sbjct: 254 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 313 Query: 342 L 342 L Sbjct: 314 L 314 Score = 86.7 bits (213), Expect = 3e-17 Identities = 72/263 (27%), Positives = 128/263 (48%), Gaps = 22/263 (8%) Query: 19 QEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAA-LHKAIMVKGVDEATIIDILTKRNNAQR 77 +E + +KS G + PS A L KA+ G DE+ +I++L R N + Sbjct: 62 KELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEI 121 Query: 78 QQIKAAYLQETGKPLDETLKKALTGHLEEVVLALL-----------KTPAQFDADELRAA 126 IK AY + + L+ +K +G+L++++++LL K A DA +L A Sbjct: 122 IAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDA 181 Query: 127 MKGL-GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAK 185 +G GTDE E+LA R+ K++R + Y+ + +D+ + I +TSGD + A L+L + Sbjct: 182 GEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVR 241 Query: 186 GDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSK 245 +D D A LY++ + GTD I+ TR+ L+ + K+ + + Sbjct: 242 --------CAQDCEDYFAERLYKS-MKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 292 Query: 246 HDMNKVLDLELKGDIEKCLTAIV 268 ++ ++ + GD K L A++ Sbjct: 293 KSLSDMVRSDTSGDFRKLLVALL 315 Score = 70.9 bits (172), Expect = 2e-12 Identities = 51/164 (31%), Positives = 88/164 (53%), Gaps = 11/164 (6%) Query: 184 AKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKY 243 AK + F V D DA+ L +A + GT+ IL+ R+ + +++ QKY Sbjct: 6 AKASSPQGFDV-----DRDAKKLNKAC-KGMGTNEAAIIEILSGRTSDERQQIKQKYKAT 59 Query: 244 SKHDMNKVLDLELKGDIEKCLTAIVKCATSKPA-FFAEKLHQAMKGVGTRHKALIRIMVS 302 ++ +VL EL G+ EK A++ +P+ + A +L +AMKG+GT LI ++ + Sbjct: 60 YGKELEEVLKSELSGNFEKTALALL----DRPSEYAARQLQKAMKGLGTDESVLIEVLCT 115 Query: 303 RSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346 R+ ++ IK YQ+++ SL + +T G+ +KILV+L N Sbjct: 116 RTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 159 >gi|4502107 annexin 5 [Homo sapiens] Length = 320 Score = 256 bits (653), Expect = 3e-68 Identities = 137/309 (44%), Positives = 196/309 (63%) Query: 36 VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95 V+ +P F+ +D L KA+ G DE +I+ +LT R+NAQRQ+I AA+ G+ L + Sbjct: 9 VTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDD 68 Query: 96 LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155 LK LTG E++++AL+K +DA EL+ A+KG GT+E L EI+ASRT +E+R I +V Sbjct: 69 LKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQV 128 Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKG 215 Y EE L D+ DTSG ++ L+ L + +R D G++E + DA+AL++AGE + G Sbjct: 129 YEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWG 188 Query: 216 TDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKP 275 TD F TI TRS LR+VF KY S + + +D E G++E+ L A+VK S P Sbjct: 189 TDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIP 248 Query: 276 AFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDY 335 A+ AE L+ AMKG GT LIR+MVSRSEID+ +I+ ++K + SL I +T GDY Sbjct: 249 AYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDY 308 Query: 336 EKILVALCG 344 +K L+ LCG Sbjct: 309 KKALLLLCG 317 Score = 80.9 bits (198), Expect = 2e-15 Identities = 51/146 (34%), Positives = 85/146 (58%), Gaps = 6/146 (4%) Query: 47 DVAALHKAIMVK-GVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLE 105 D AL +A +K G DE I I R+ + +++ Y+ +G ++ET+ + +G+LE Sbjct: 175 DAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLE 234 Query: 106 EVVLALLKT----PAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELK 161 +++LA++K+ PA A+ L AMKG GTD+ TLI ++ SR+ ++ +I + +R+ Sbjct: 235 QLLLAVVKSIRSIPAYL-AETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFA 293 Query: 162 RDLAKDITSDTSGDFRNALLSLAKGD 187 L I DTSGD++ ALL L D Sbjct: 294 TSLYSMIKGDTSGDYKKALLLLCGED 319 Score = 73.2 bits (178), Expect = 3e-13 Identities = 48/146 (32%), Positives = 76/146 (52%), Gaps = 4/146 (2%) Query: 201 SDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDI 260 +DA L +A + GTD T+LT+RS Q + + + D+ L EL G Sbjct: 19 ADAETLRKA-MKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKF 77 Query: 261 EKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYG 320 EK + A++K + A+ +L A+KG GT K L I+ SR+ ++ IK Y++ YG Sbjct: 78 EKLIVALMKPSRLYDAY---ELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYG 134 Query: 321 ISLCQAILDETKGDYEKILVALCGGN 346 SL ++ +T G Y+++LV L N Sbjct: 135 SSLEDDVVGDTSGYYQRMLVVLLQAN 160 >gi|48762937 annexin A10 [Homo sapiens] Length = 324 Score = 219 bits (557), Expect = 4e-57 Identities = 124/311 (39%), Positives = 184/311 (59%), Gaps = 1/311 (0%) Query: 36 VSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDET 95 + P P FNP D L A+ D+ +I+ILT+R NAQR I AY G+ L Sbjct: 11 IFPAPNFNPIMDAQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGD 70 Query: 96 LKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRV 155 +++ L+ H ++V+ L+ P +DA EL AMKG+GTDE+ LIEILASRTN EI + Sbjct: 71 MREQLSDHFKDVMAGLMYPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQMREA 130 Query: 156 YREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGERRKG 215 Y + +L +DI S+TSG FR+ L++L +G R E + + +A DA L+EA +++ G Sbjct: 131 YCLQYSNNLQEDIYSETSGHFRDTLMNLVQGTREEGY-TDPAMAAQDAMVLWEACQQKTG 189 Query: 216 TDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKP 275 + IL +SY QLR VFQ++ S DM ++ G ++ L AIV C KP Sbjct: 190 EHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIVLCVRDKP 249 Query: 276 AFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDY 335 A+FA +L+ A+ G +K +IRI+++RSEID+ I+ Y++ YG SL I + G Y Sbjct: 250 AYFAYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERYGKSLFHDIRNFASGHY 309 Query: 336 EKILVALCGGN 346 +K L+A+C G+ Sbjct: 310 KKALLAICAGD 320 Score = 55.1 bits (131), Expect = 9e-08 Identities = 39/153 (25%), Positives = 79/153 (51%), Gaps = 7/153 (4%) Query: 45 SSDVAALHKAIMVKGVDEATIID-ILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGH 103 + D L +A K + T++ IL ++ Q + + + +G+ + + + + G+ Sbjct: 174 AQDAMVLWEACQQKTGEHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGY 233 Query: 104 LEEVVLALL----KTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREE 159 +E+++A++ PA F A L +A+ G T+I IL +R+ ++ I + Y+E Sbjct: 234 FQELLVAIVLCVRDKPAYF-AYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKER 292 Query: 160 LKRDLAKDITSDTSGDFRNALLSLAKGDRSEDF 192 + L DI + SG ++ ALL++ GD +ED+ Sbjct: 293 YGKSLFHDIRNFASGHYKKALLAICAGD-AEDY 324 >gi|145864465 annexin A9 [Homo sapiens] Length = 345 Score = 201 bits (512), Expect = 6e-52 Identities = 118/320 (36%), Positives = 188/320 (58%), Gaps = 6/320 (1%) Query: 26 KSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYL 85 K++ G + + F+ D L +AI +GVD + I+D+LT R+ QRQ I + Sbjct: 25 KTAAWGTLGTLRTFLNFSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQ 84 Query: 86 QETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRT 145 + T + L ++L+ AL+G+LE +V+ALL+ AQFDA ELR A+K + D IEILA+RT Sbjct: 85 ERTQQDLMKSLQAALSGNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRT 144 Query: 146 NKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFG-VNEDLADSDAR 204 ++++ VY+ + + DITS+TSG ++ LL+LAKG R G ++ +LA+ D + Sbjct: 145 PPQLQECLAVYKHNFQVEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAEQDVQ 204 Query: 205 ALYEA-GERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKC 263 AL A G R+ T V VF T R+ L RVF +Y + + ++ + + GD + Sbjct: 205 ALQRAEGPSREETWVPVF----TQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVA 260 Query: 264 LTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISL 323 L + + P +FA+KLHQA++ ++ LIRI++SR E D+ I+A ++K +G SL Sbjct: 261 LLGLASVIKNTPLYFADKLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSL 320 Query: 324 CQAILDETKGDYEKILVALC 343 ++ D KGD + L+ALC Sbjct: 321 YSSLQDAVKGDCQSALLALC 340 Score = 55.8 bits (133), Expect = 5e-08 Identities = 43/164 (26%), Positives = 76/164 (46%), Gaps = 7/164 (4%) Query: 28 SKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVD-EATIIDILTKRNNAQRQQIKAAYLQ 86 +KGG S DV AL +A +G E T + + T+RN ++ Y + Sbjct: 183 AKGGRDSYSGIIDYNLAEQDVQALQRA---EGPSREETWVPVFTQRNPEHLIRVFDQYQR 239 Query: 87 ETGKPLDETLKKALTGHLEEVVLAL---LKTPAQFDADELRAAMKGLGTDEDTLIEILAS 143 TG+ L+E ++ G + +L L +K + AD+L A++ + LI IL S Sbjct: 240 STGQELEEAVQNRFHGDAQVALLGLASVIKNTPLYFADKLHQALQETEPNYQVLIRILIS 299 Query: 144 RTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGD 187 R ++ I +R++ + L + GD ++ALL+L + + Sbjct: 300 RCETDLLSIRAEFRKKFGKSLYSSLQDAVKGDCQSALLALCRAE 343 >gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo sapiens] Length = 112 Score = 95.1 bits (235), Expect = 8e-20 Identities = 49/108 (45%), Positives = 69/108 (63%) Query: 221 FNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCATSKPAFFAE 280 F TIL TRS L RVF++Y K + + + E G +E+ + +VKC + ++FAE Sbjct: 3 FITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAE 62 Query: 281 KLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAIL 328 +L+ AMKG GTR LIR +VSRSEID+N IK ++KMYG +L I+ Sbjct: 63 RLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIM 110 Score = 42.4 bits (98), Expect = 6e-04 Identities = 29/106 (27%), Positives = 53/106 (50%), Gaps = 3/106 (2%) Query: 66 IDILTKRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQ---FDADE 122 I IL R+ ++ Y + K +++++K G LEE +L ++K + A+ Sbjct: 4 ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAER 63 Query: 123 LRAAMKGLGTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDI 168 L AMKG GT + TLI + SR+ ++ I +++ + L+ I Sbjct: 64 LYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109 >gi|188497635 cell division cycle associated 7-like isoform 2 [Homo sapiens] Length = 420 Score = 30.8 bits (68), Expect = 1.9 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%) Query: 127 MKGLGTDEDT-LIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAK 185 M+ L ++E + L S +++R ++ + EEL+R +D S+T DF S Sbjct: 1 METLSSEESCDSFDSLESGKQQDVRFHSKYFTEELRRIFIEDTDSETE-DFAGFTQSDLN 59 Query: 186 GDRS-EDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTK 242 G + E V DL+D +L E + D + RS LR FQ TK Sbjct: 60 GKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTK 117 >gi|31542537 cell division cycle associated 7-like isoform 1 [Homo sapiens] Length = 454 Score = 30.8 bits (68), Expect = 1.9 Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 3/118 (2%) Query: 127 MKGLGTDEDT-LIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAK 185 M+ L ++E + L S +++R ++ + EEL+R +D S+T DF S Sbjct: 35 METLSSEESCDSFDSLESGKQQDVRFHSKYFTEELRRIFIEDTDSETE-DFAGFTQSDLN 93 Query: 186 GDRS-EDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTK 242 G + E V DL+D +L E + D + RS LR FQ TK Sbjct: 94 GKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTK 151 >gi|148539855 epidermal growth factor receptor pathway substrate 8-like protein 1 isoform b [Homo sapiens] Length = 596 Score = 30.4 bits (67), Expect = 2.4 Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 11/103 (10%) Query: 14 IENEEQEYVQTVKSSKGGPGSAV----SPYPTFNPSSDVAALHKAIMVKGVDEATI--ID 67 I NEE + + + GP AV +P P +P SD + + + KG T+ + Sbjct: 473 IVNEELQ--ARLAQGRSGPSRAVPGPRAPEPQLSPGSDASEVRAWLQAKGFSSGTVDALG 530 Query: 68 ILTKRN--NAQRQQIKAAYLQETGKPLDE-TLKKALTGHLEEV 107 +LT + Q+++++A +E + + T++++L E+V Sbjct: 531 VLTGAQLFSLQKEELRAVSPEEGARVYSQVTVQRSLLEDKEKV 573 >gi|148539853 epidermal growth factor receptor pathway substrate 8-like protein 1 isoform a [Homo sapiens] Length = 723 Score = 30.4 bits (67), Expect = 2.4 Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 11/103 (10%) Query: 14 IENEEQEYVQTVKSSKGGPGSAV----SPYPTFNPSSDVAALHKAIMVKGVDEATI--ID 67 I NEE + + + GP AV +P P +P SD + + + KG T+ + Sbjct: 600 IVNEELQ--ARLAQGRSGPSRAVPGPRAPEPQLSPGSDASEVRAWLQAKGFSSGTVDALG 657 Query: 68 ILTKRN--NAQRQQIKAAYLQETGKPLDE-TLKKALTGHLEEV 107 +LT + Q+++++A +E + + T++++L E+V Sbjct: 658 VLTGAQLFSLQKEELRAVSPEEGARVYSQVTVQRSLLEDKEKV 700 >gi|170650672 Leber congenital amaurosis 5 [Homo sapiens] Length = 697 Score = 29.6 bits (65), Expect = 4.1 Identities = 37/136 (27%), Positives = 56/136 (41%), Gaps = 7/136 (5%) Query: 128 KGLGTDEDTLIEI--LASRTNKEIRDINRVYR--EELKRDLAKDITSDTSGDFRN--ALL 181 K L ED EI L R N EI + R +E +R K + S FR +L Sbjct: 145 KALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQ 204 Query: 182 SLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYT 241 L + + +DLA A + + + N L+T S+ Q + + ++ Sbjct: 205 KLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSF-QRQLLAERKR 263 Query: 242 KYSKHDMNKVLDLELK 257 Y HD NKVL E++ Sbjct: 264 AYEAHDENKVLQKEVQ 279 >gi|170650670 Leber congenital amaurosis 5 [Homo sapiens] Length = 697 Score = 29.6 bits (65), Expect = 4.1 Identities = 37/136 (27%), Positives = 56/136 (41%), Gaps = 7/136 (5%) Query: 128 KGLGTDEDTLIEI--LASRTNKEIRDINRVYR--EELKRDLAKDITSDTSGDFRN--ALL 181 K L ED EI L R N EI + R +E +R K + S FR +L Sbjct: 145 KALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQ 204 Query: 182 SLAKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYT 241 L + + +DLA A + + + N L+T S+ Q + + ++ Sbjct: 205 KLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSF-QRQLLAERKR 263 Query: 242 KYSKHDMNKVLDLELK 257 Y HD NKVL E++ Sbjct: 264 AYEAHDENKVLQKEVQ 279 >gi|145312241 differentially expressed in FDCP 6 homolog [Homo sapiens] Length = 631 Score = 29.3 bits (64), Expect = 5.4 Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 28/163 (17%) Query: 71 KRNNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGL 130 K A RQ+ + L+E + L E L+ L+ A+ D + +R A L Sbjct: 417 KEEEAARQRQRIKELEEMQQRLQEALQ--------------LEVKARRDEESVRIAQTRL 462 Query: 131 GTDEDTLIEILASRTNKEIRDINRVY--REELKRDLAKDITSDTSGDFRNALLSLAKGDR 188 +E+ ++ L ++ R I R +EEL++++A+ S L A+ + Sbjct: 463 LEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRS----------LQQAQ-QQ 511 Query: 189 SEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYP 231 E+ N AD D A + R+ T+V +N + +P Sbjct: 512 LEEVRQNRQRADEDVEAA-QRKLRQASTNVKHWNVQMNRLMHP 553 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.365 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,857,639 Number of Sequences: 37866 Number of extensions: 481848 Number of successful extensions: 1639 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 23 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 1405 Number of HSP's gapped (non-prelim): 61 length of query: 346 length of database: 18,247,518 effective HSP length: 103 effective length of query: 243 effective length of database: 14,347,320 effective search space: 3486398760 effective search space used: 3486398760 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.