Guide to the Human Genome
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Search of human proteins with 42794618

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42794618 transmembrane protein 81 [Homo sapiens]
         (255 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42794618 transmembrane protein 81 [Homo sapiens]                   516   e-147
gi|13569934 sperm acrosome associated 1 [Homo sapiens]                 39   0.004
gi|46852398 biogenesis of lysosome-related organelles complex-1,...    33   0.32 
gi|47717129 biogenesis of lysosome-related organelles complex-1,...    30   2.7  
gi|217416354 sphingosine kinase type 1-interacting protein isofo...    29   3.5  
gi|217416352 sphingosine kinase type 1-interacting protein isofo...    29   3.5  
gi|21359873 polo-like kinase 1 [Homo sapiens]                          29   4.6  
gi|118572606 hemicentin 1 [Homo sapiens]                               28   7.8  

>gi|42794618 transmembrane protein 81 [Homo sapiens]
          Length = 255

 Score =  516 bits (1330), Expect = e-147
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MKVLATSFVLGSLGLAFYLPLVVTTPKTLAIPEKLQEAVGKVIINATTCTVTCGLGYKEE 60
           MKVLATSFVLGSLGLAFYLPLVVTTPKTLAIPEKLQEAVGKVIINATTCTVTCGLGYKEE
Sbjct: 1   MKVLATSFVLGSLGLAFYLPLVVTTPKTLAIPEKLQEAVGKVIINATTCTVTCGLGYKEE 60

Query: 61  TVCEVGPDGVRRKCQTRRLECLTNWICGMLHFTILIGKEFELSCLSSDILEFGQEAFRFT 120
           TVCEVGPDGVRRKCQTRRLECLTNWICGMLHFTILIGKEFELSCLSSDILEFGQEAFRFT
Sbjct: 61  TVCEVGPDGVRRKCQTRRLECLTNWICGMLHFTILIGKEFELSCLSSDILEFGQEAFRFT 120

Query: 121 WRLARGVISTDDEVFKPFQANSHFVKFKYAQEYDSGTYRCDVQLVKNLRLVKRLYFGLRV 180
           WRLARGVISTDDEVFKPFQANSHFVKFKYAQEYDSGTYRCDVQLVKNLRLVKRLYFGLRV
Sbjct: 121 WRLARGVISTDDEVFKPFQANSHFVKFKYAQEYDSGTYRCDVQLVKNLRLVKRLYFGLRV 180

Query: 181 LPPNLVNLNFHQSLTEDQKLIDEGLEVNLDSYSKPHHPKWKKKVASALGIGIAIGVVGGV 240
           LPPNLVNLNFHQSLTEDQKLIDEGLEVNLDSYSKPHHPKWKKKVASALGIGIAIGVVGGV
Sbjct: 181 LPPNLVNLNFHQSLTEDQKLIDEGLEVNLDSYSKPHHPKWKKKVASALGIGIAIGVVGGV 240

Query: 241 LVRIVLCALRGGLQQ 255
           LVRIVLCALRGGLQQ
Sbjct: 241 LVRIVLCALRGGLQQ 255


>gi|13569934 sperm acrosome associated 1 [Homo sapiens]
          Length = 294

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 9/104 (8%)

Query: 49  CTVTCGLGYKEETVCEVGPDGVRRKCQTRRLECLTNWICGMLHFTILIGKEFELSCLSSD 108
           CTVTCG+G + E +   G  G   KC  R  EC     CG         +   L+C+ + 
Sbjct: 84  CTVTCGIGVR-EVILTNGCPGGESKCVVRVEECRGPTDCGWGKPISESLESVRLACIHTS 142

Query: 109 ILEFGQEAFRFTWRLAR----GVISTDDEVFKPFQANSHFVKFK 148
            L      F++ W+L R     +I  +D      +  SH + F+
Sbjct: 143 PL----NRFKYMWKLLRQDQQSIILVNDSAILEVRKESHPLAFE 182


>gi|46852398 biogenesis of lysosome-related organelles complex-1,
           subunit 2 isoform 1 [Homo sapiens]
          Length = 142

 Score = 32.7 bits (73), Expect = 0.32
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 12/116 (10%)

Query: 107 SDILEFGQEAFRFTWRLARGVISTDDEVFKPFQANSHFVKFKYAQEYDSGTYRCDVQLVK 166
           +DI E  ++ F        G ++   E +K  +  +     KY +  D       + + +
Sbjct: 35  ADITELCRDMFSKMATYLTGELTATSEDYKLLENMNKLTSLKYLEMKDIA-----INISR 89

Query: 167 NLRLVKRLYFGLRVLPPNLVNLNFHQSLTEDQKLIDEGLEVNLDSYSKPHHPKWKK 222
           NL+ + + Y GL+   P L  +N    + E+Q    E     LD+YSK    K+KK
Sbjct: 90  NLKDLNQKYAGLQ---PYLDQIN----VIEEQVAALEQAAYKLDAYSKKLEAKYKK 138


>gi|47717129 biogenesis of lysosome-related organelles complex-1,
           subunit 2 isoform 2 [Homo sapiens]
          Length = 99

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 12/97 (12%)

Query: 126 GVISTDDEVFKPFQANSHFVKFKYAQEYDSGTYRCDVQLVKNLRLVKRLYFGLRVLPPNL 185
           G ++   E +K  +  +     KY +  D       + + +NL+ + + Y GL+   P L
Sbjct: 11  GELTATSEDYKLLENMNKLTSLKYLEMKDIA-----INISRNLKDLNQKYAGLQ---PYL 62

Query: 186 VNLNFHQSLTEDQKLIDEGLEVNLDSYSKPHHPKWKK 222
             +N    + E+Q    E     LD+YSK    K+KK
Sbjct: 63  DQIN----VIEEQVAALEQAAYKLDAYSKKLEAKYKK 95


>gi|217416354 sphingosine kinase type 1-interacting protein isoform
           1 [Homo sapiens]
          Length = 1700

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 20/72 (27%), Positives = 30/72 (41%), Gaps = 8/72 (11%)

Query: 1   MKVLATSFVLGSLGLAFYLPLVVTTPKTLAIPEKLQEAVGKVIINAT---TCTVTCGLGY 57
           M+ + ++F  GS G      L    P+ L  P   + +    +   T   +    CGLG 
Sbjct: 521 MEQVVSNFPPGSSGA-----LQTQAPQGLKEPSINEYSFPSALCGMTQVASAVAVCGLGE 575

Query: 58  KEETVCEVGPDG 69
           +EE  C V P G
Sbjct: 576 REEVTCSVAPSG 587


>gi|217416352 sphingosine kinase type 1-interacting protein isoform
           2 [Homo sapiens]
          Length = 1671

 Score = 29.3 bits (64), Expect = 3.5
 Identities = 20/72 (27%), Positives = 30/72 (41%), Gaps = 8/72 (11%)

Query: 1   MKVLATSFVLGSLGLAFYLPLVVTTPKTLAIPEKLQEAVGKVIINAT---TCTVTCGLGY 57
           M+ + ++F  GS G      L    P+ L  P   + +    +   T   +    CGLG 
Sbjct: 521 MEQVVSNFPPGSSGA-----LQTQAPQGLKEPSINEYSFPSALCGMTQVASAVAVCGLGE 575

Query: 58  KEETVCEVGPDG 69
           +EE  C V P G
Sbjct: 576 REEVTCSVAPSG 587


>gi|21359873 polo-like kinase 1 [Homo sapiens]
          Length = 603

 Score = 28.9 bits (63), Expect = 4.6
 Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 8/67 (11%)

Query: 56  GYKEETVCE----VGPDGVRRKCQTRRLECLTNWICGMLHFTILIGK-EFELSCLSSDIL 110
           G +++T+C     + P+ + +K  +  ++    W  G + +T+L+GK  FE SCL    L
Sbjct: 205 GERKKTLCGTPNYIAPEVLSKKGHSFEVDV---WSIGCIMYTLLVGKPPFETSCLKETYL 261

Query: 111 EFGQEAF 117
              +  +
Sbjct: 262 RIKKNEY 268


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 28.1 bits (61), Expect = 7.8
 Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 12/78 (15%)

Query: 128  ISTDDEVFKPFQANSHFVKFKYAQEYDSGTYRCDVQLVKNLRLVKRLYFGLRV-LPPNLV 186
            + +DD V     AN H ++ K AQ  D+G Y C   +  N+     L F + + +PP+  
Sbjct: 2715 LKSDDHV--NIAANGHTLQIKEAQISDTGRYTC---VASNIAGEDELDFDVNIQVPPSF- 2768

Query: 187  NLNFHQSLTEDQKLIDEG 204
                 Q L E   ++D G
Sbjct: 2769 -----QKLWEIGNMLDTG 2781


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.141    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,493,968
Number of Sequences: 37866
Number of extensions: 397859
Number of successful extensions: 939
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 935
Number of HSP's gapped (non-prelim): 9
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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