Guide to the Human Genome
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Search of human proteins with 42789729

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42789729 lymphoid-restricted membrane protein [Homo sapiens]
         (499 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42789729 lymphoid-restricted membrane protein [Homo sapiens]       987   0.0  
gi|148747864 JAW1-related protein isoform a [Homo sapiens]            133   3e-31
gi|154091334 JAW1-related protein isoform c [Homo sapiens]            133   3e-31
gi|154091332 JAW1-related protein isoform b [Homo sapiens]            133   3e-31
gi|148728182 JAW1-related protein isoform b [Homo sapiens]            133   3e-31
gi|110347443 TATA element modulatory factor 1 [Homo sapiens]           47   5e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     45   2e-04
gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]        44   4e-04
gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]           43   6e-04
gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]           43   6e-04
gi|32528293 ecto-NOX disulfide-thiol exchanger 2 isoform a [Homo...    42   0.001
gi|32528291 ecto-NOX disulfide-thiol exchanger 2 isoform b [Homo...    42   0.001
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    41   0.003
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    41   0.003
gi|38044112 restin isoform b [Homo sapiens]                            40   0.005
gi|4506751 restin isoform a [Homo sapiens]                             40   0.005
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       40   0.005
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    40   0.006
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    39   0.008
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]               39   0.008
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]               39   0.008
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]               39   0.008
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         39   0.008
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         39   0.008
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    39   0.011
gi|71061468 centromere protein E [Homo sapiens]                        39   0.011
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       39   0.011
gi|122937396 coiled-coil domain containing 150 [Homo sapiens]          39   0.011
gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]           39   0.014
gi|109134347 NY-REN-58 antigen [Homo sapiens]                          39   0.014

>gi|42789729 lymphoid-restricted membrane protein [Homo sapiens]
          Length = 499

 Score =  987 bits (2552), Expect = 0.0
 Identities = 499/499 (100%), Positives = 499/499 (100%)

Query: 1   MNDDPSMEENGVERVCPESLLQSREYSSLPLPRHTSSTDGTITSSDPGLEILNMASCDLD 60
           MNDDPSMEENGVERVCPESLLQSREYSSLPLPRHTSSTDGTITSSDPGLEILNMASCDLD
Sbjct: 1   MNDDPSMEENGVERVCPESLLQSREYSSLPLPRHTSSTDGTITSSDPGLEILNMASCDLD 60

Query: 61  RNSLCKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKDKTILNLEAKEEPETIEEHKKE 120
           RNSLCKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKDKTILNLEAKEEPETIEEHKKE
Sbjct: 61  RNSLCKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKDKTILNLEAKEEPETIEEHKKE 120

Query: 121 HASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEE 180
           HASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEE
Sbjct: 121 HASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEE 180

Query: 181 RSRDLAEENLKKEITNCLKLLESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAE 240
           RSRDLAEENLKKEITNCLKLLESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAE
Sbjct: 181 RSRDLAEENLKKEITNCLKLLESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAE 240

Query: 241 MLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQ 300
           MLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQ
Sbjct: 241 MLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQ 300

Query: 301 IKKRSASLNSKPSSLRRVTIASLPRNIGNAGMVAGMENNDRFSRRSSSWRILGSKQSEHR 360
           IKKRSASLNSKPSSLRRVTIASLPRNIGNAGMVAGMENNDRFSRRSSSWRILGSKQSEHR
Sbjct: 301 IKKRSASLNSKPSSLRRVTIASLPRNIGNAGMVAGMENNDRFSRRSSSWRILGSKQSEHR 360

Query: 361 PSLPRFISTYSWADAEEEKCELKTKDDSEPSGEETVERTRKPSLSEKKNNPSKWDVSSVY 420
           PSLPRFISTYSWADAEEEKCELKTKDDSEPSGEETVERTRKPSLSEKKNNPSKWDVSSVY
Sbjct: 361 PSLPRFISTYSWADAEEEKCELKTKDDSEPSGEETVERTRKPSLSEKKNNPSKWDVSSVY 420

Query: 421 DTIASWATNLKSSIRKANKALWLSIAFIVLFAALMSFLTGQLFQKSVDAAPTQQEDSWTS 480
           DTIASWATNLKSSIRKANKALWLSIAFIVLFAALMSFLTGQLFQKSVDAAPTQQEDSWTS
Sbjct: 421 DTIASWATNLKSSIRKANKALWLSIAFIVLFAALMSFLTGQLFQKSVDAAPTQQEDSWTS 480

Query: 481 LEHILWPFTRLRHNGPPPV 499
           LEHILWPFTRLRHNGPPPV
Sbjct: 481 LEHILWPFTRLRHNGPPPV 499


>gi|148747864 JAW1-related protein isoform a [Homo sapiens]
          Length = 903

 Score =  133 bits (335), Expect = 3e-31
 Identities = 89/215 (41%), Positives = 128/215 (59%), Gaps = 12/215 (5%)

Query: 118 KKEHASGDSVVSPLPVTTVKSVNLRQSENTSA---NEKEVEAEFLRLSLGFKCDWFTLEK 174
           ++E  SG  V+  +    ++ + + +S   SA    EKEVE  F++LSL F+ D +TLE 
Sbjct: 485 EEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLES 544

Query: 175 RVKLEERSRDLAEENLKKEITNCLKLLESLTPL---CEDDNQAQEIIKKLEKSIKFLSQC 231
           R+   ER R+L EEN +KE+ N    + S   L   CE     +E  +KL + I  L + 
Sbjct: 545 RINQAERERNLTEENTEKELENFKASITSSASLWHHCEH----RETYQKLLEDIAVLHRL 600

Query: 232 AARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVLLQN-ERSF 290
           AAR++SRAE++GA+ QE R+SKA EVM+Q+VENLKR Y K+HAEL E K++  QN  RS 
Sbjct: 601 AARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSC 660

Query: 291 NPLEDDDDCQIKKRSASLNSKPSSLRRVTIASLPR 325
            P ED      +  S +L  K    RRV++A +P+
Sbjct: 661 GPSEDGVPRTARSMSLTL-GKNMPRRRVSVAVVPK 694


>gi|154091334 JAW1-related protein isoform c [Homo sapiens]
          Length = 597

 Score =  133 bits (335), Expect = 3e-31
 Identities = 89/215 (41%), Positives = 128/215 (59%), Gaps = 12/215 (5%)

Query: 118 KKEHASGDSVVSPLPVTTVKSVNLRQSENTSA---NEKEVEAEFLRLSLGFKCDWFTLEK 174
           ++E  SG  V+  +    ++ + + +S   SA    EKEVE  F++LSL F+ D +TLE 
Sbjct: 179 EEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLES 238

Query: 175 RVKLEERSRDLAEENLKKEITNCLKLLESLTPL---CEDDNQAQEIIKKLEKSIKFLSQC 231
           R+   ER R+L EEN +KE+ N    + S   L   CE     +E  +KL + I  L + 
Sbjct: 239 RINQAERERNLTEENTEKELENFKASITSSASLWHHCEH----RETYQKLLEDIAVLHRL 294

Query: 232 AARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVLLQN-ERSF 290
           AAR++SRAE++GA+ QE R+SKA EVM+Q+VENLKR Y K+HAEL E K++  QN  RS 
Sbjct: 295 AARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSC 354

Query: 291 NPLEDDDDCQIKKRSASLNSKPSSLRRVTIASLPR 325
            P ED      +  S +L  K    RRV++A +P+
Sbjct: 355 GPSEDGVPRTARSMSLTL-GKNMPRRRVSVAVVPK 388


>gi|154091332 JAW1-related protein isoform b [Homo sapiens]
          Length = 821

 Score =  133 bits (335), Expect = 3e-31
 Identities = 89/215 (41%), Positives = 128/215 (59%), Gaps = 12/215 (5%)

Query: 118 KKEHASGDSVVSPLPVTTVKSVNLRQSENTSA---NEKEVEAEFLRLSLGFKCDWFTLEK 174
           ++E  SG  V+  +    ++ + + +S   SA    EKEVE  F++LSL F+ D +TLE 
Sbjct: 403 EEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLES 462

Query: 175 RVKLEERSRDLAEENLKKEITNCLKLLESLTPL---CEDDNQAQEIIKKLEKSIKFLSQC 231
           R+   ER R+L EEN +KE+ N    + S   L   CE     +E  +KL + I  L + 
Sbjct: 463 RINQAERERNLTEENTEKELENFKASITSSASLWHHCEH----RETYQKLLEDIAVLHRL 518

Query: 232 AARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVLLQN-ERSF 290
           AAR++SRAE++GA+ QE R+SKA EVM+Q+VENLKR Y K+HAEL E K++  QN  RS 
Sbjct: 519 AARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSC 578

Query: 291 NPLEDDDDCQIKKRSASLNSKPSSLRRVTIASLPR 325
            P ED      +  S +L  K    RRV++A +P+
Sbjct: 579 GPSEDGVPRTARSMSLTL-GKNMPRRRVSVAVVPK 612


>gi|148728182 JAW1-related protein isoform b [Homo sapiens]
          Length = 821

 Score =  133 bits (335), Expect = 3e-31
 Identities = 89/215 (41%), Positives = 128/215 (59%), Gaps = 12/215 (5%)

Query: 118 KKEHASGDSVVSPLPVTTVKSVNLRQSENTSA---NEKEVEAEFLRLSLGFKCDWFTLEK 174
           ++E  SG  V+  +    ++ + + +S   SA    EKEVE  F++LSL F+ D +TLE 
Sbjct: 403 EEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLES 462

Query: 175 RVKLEERSRDLAEENLKKEITNCLKLLESLTPL---CEDDNQAQEIIKKLEKSIKFLSQC 231
           R+   ER R+L EEN +KE+ N    + S   L   CE     +E  +KL + I  L + 
Sbjct: 463 RINQAERERNLTEENTEKELENFKASITSSASLWHHCEH----RETYQKLLEDIAVLHRL 518

Query: 232 AARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVLLQN-ERSF 290
           AAR++SRAE++GA+ QE R+SKA EVM+Q+VENLKR Y K+HAEL E K++  QN  RS 
Sbjct: 519 AARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSC 578

Query: 291 NPLEDDDDCQIKKRSASLNSKPSSLRRVTIASLPR 325
            P ED      +  S +L  K    RRV++A +P+
Sbjct: 579 GPSEDGVPRTARSMSLTL-GKNMPRRRVSVAVVPK 612


>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
          Length = 1093

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 77/338 (22%), Positives = 149/338 (44%), Gaps = 41/338 (12%)

Query: 6   SMEENGVERVCPESLLQSREYSSLPLPRHTSSTDG-TITSSDPGLEILNMASCDLDRNSL 64
           S++   V  +  +  L  + Y+ +P+  ++S+    T+ S++   E +N         + 
Sbjct: 333 SLDSRSVSEINSDDELSGKGYALVPIIVNSSTPKSKTVESAEGKSEEVNETLVIPTEEA- 391

Query: 65  CKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKDKTILNLE-AKEEPETIEEHKKEHAS 123
            + EE  RSA+P    Q           +  T  DK     E A+ +PE + E +    +
Sbjct: 392 -EMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKT 450

Query: 124 GDSVVSPLPVTTVKSVNLRQS----ENTSANEKEVEAEFLRL-----SLGFKCDWFT--- 171
            + +   L     + ++L +     E    N K+   E  R+     S+    D FT   
Sbjct: 451 VEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKD---EMFRVKEESSSISSLKDEFTQRI 507

Query: 172 --LEKRVKLEERSRDLAEE---NLKKEITNCLKLLESLTPLCEDDNQAQEIIKKLEKSIK 226
              EK+V+L  + RD A++   N+K+E+   L   E+   L E D Q + ++++ EK  K
Sbjct: 508 AEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLSK 567

Query: 227 -------FLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENL---KRMYAKEHAE- 275
                   + +  A+      M+  +N++    K +E  +QH++ +   K    K+H E 
Sbjct: 568 QQLHNSNIIKKLRAKDKENENMVAKLNKK---VKELEEELQHLKQVLDGKEEVEKQHREN 624

Query: 276 LEELKQVLLQNERSFNPLE-DDDDCQIKKRS--ASLNS 310
           +++L  ++ + E+    L+ D D+ + K RS  A+L+S
Sbjct: 625 IKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDS 662



 Score = 33.1 bits (74), Expect = 0.60
 Identities = 51/257 (19%), Positives = 107/257 (41%), Gaps = 51/257 (19%)

Query: 55   ASCDLDRNSLCKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKDKTILNLEAKEEPETI 114
            A  + ++N LCK E++       +E    +   + +   + T K+KT+LN + + E   +
Sbjct: 847  AQLESEKNRLCKLEDENNRYQVELE----NLKDEYVRTLEETRKEKTLLNSQLEMERMKV 902

Query: 115  EEHKKE----------------------HASGDSVVSPLPVTTVKSVNLRQSEN------ 146
            E+ +K+                        S  S +S + +  +++  L Q E+      
Sbjct: 903  EQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQDESHDHSFG 962

Query: 147  ---TSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLK---- 199
                SAN   +  + +R+  G      ++ + ++ + + R+    +L+ EI N  K    
Sbjct: 963  PMPISANGSNL-YDAVRMGAG-----SSIIENLQSQLKLREGEITHLQLEIGNLEKTRSI 1016

Query: 200  LLESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMI 259
            + E L  L   +++ +E +K++ K    L     R  +  +M G   +E+      E + 
Sbjct: 1017 MAEELVKLTNQNDELEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEA------EELR 1070

Query: 260  QHVENLKRMYAKEHAEL 276
              +E++K MY  +  EL
Sbjct: 1071 LDLEDVKNMYKTQIDEL 1087


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 56/236 (23%), Positives = 103/236 (43%), Gaps = 15/236 (6%)

Query: 60   DRNSLCKKEEDTRSASPTIEAQGTS---PAHDNIAFQDSTSKDKTILNL-------EAKE 109
            +R S  K E+  R     +EA  T          A Q+  SK +  +N+       EAK 
Sbjct: 1123 ERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKT 1182

Query: 110  EPETIEEHKKEHASG-DSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGFKCD 168
                I+E +++H+   + +   L  T     NL +++ T  NE+   A  +++ L  K D
Sbjct: 1183 HEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGD 1242

Query: 169  WFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESLTPL-CEDDNQAQEIIKKLEKSIKF 227
              +  KR K+E + ++L  +  + E     +L + +T L  E DN    + +   KS K 
Sbjct: 1243 --SEHKRKKVEAQLQELQVKFNEGERVR-TELADKVTKLQVELDNVTGLLSQSDSKSSKL 1299

Query: 228  LSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVL 283
                +A  +   +    + +E+R   ++   ++ VE+ K  + ++  E EE K  L
Sbjct: 1300 TKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNL 1355



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 9/101 (8%)

Query: 137  KSVNLRQSENTSANEKEVEAEFLRLSLGFKCDWFTLEK---RVKLEERSRDLAEENLKKE 193
            K  +  +S+     E   E    +LSL  K      EK   R +LEE     A+ NL+K+
Sbjct: 1301 KDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEE--AKHNLEKQ 1358

Query: 194  ITNCLKLLESLTPLCEDD----NQAQEIIKKLEKSIKFLSQ 230
            I      +  +    ED       A+E+ +KL+K ++ LSQ
Sbjct: 1359 IATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 1399


>gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]
          Length = 388

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 53/229 (23%), Positives = 102/229 (44%), Gaps = 47/229 (20%)

Query: 90  IAFQDSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPL----------PVTTVKSV 139
           + F++ T   K  L++E ++  + I+++KKE       +S L           VTT+K  
Sbjct: 118 LLFKEET---KLQLDIEKEKHQDVIQKYKKEQEELQMKISDLITGATRDLRQEVTTLKEK 174

Query: 140 ----NLRQSENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEI- 194
               + R +E +++ EKE+E          K      E R+K E  S D   ENL+KE+ 
Sbjct: 175 LHKSHTRYTEESNSKEKEIE--------NLKNLVAEFESRLKKEIDSNDSVSENLRKEME 226

Query: 195 ---TNCLKLLESLTPLCEDDNQAQEIIKKLEKSIK-----------FLSQCAARVASRAE 240
                  +++ + T L E  NQ+QE    L+++++            LSQ   ++   ++
Sbjct: 227 QKSDELKRVMLAQTQLIEQFNQSQEENTFLQETVRRECEERFELTEALSQAREQLLELSK 286

Query: 241 MLG-------AINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQV 282
           + G       ++++ S  S A  V      +L R+ +++  ++  L+ V
Sbjct: 287 LRGSLPFSPCSLSKGSLTSPAAAVSNHGERSLARLNSEKGIQIPNLRGV 335



 Score = 29.3 bits (64), Expect = 8.7
 Identities = 47/212 (22%), Positives = 96/212 (45%), Gaps = 21/212 (9%)

Query: 100 KTILNLEAKEEPETIE-EHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKE-VEAE 157
           KT+LN + +EE  T++ E +    S    +  L  T      LRQ   +  N KE +EAE
Sbjct: 49  KTLLN-QTREEVLTLKNERELMLISHQKSIEQLQET------LRQKLLSDDNWKEKIEAE 101

Query: 158 FLRLSLGFKCDW------FTLEKRVKLE---ERSRDLAEENLKKEITNCLKLLESLTPLC 208
             +       ++      F  E +++L+   E+ +D+ ++  K++    +K+ + +T   
Sbjct: 102 LAKERAQHLVEFEEQALLFKEETKLQLDIEKEKHQDVIQKYKKEQEELQMKISDLITGAT 161

Query: 209 EDDNQAQEIIK-KLEKS-IKFLSQCAARVASRAEMLGAINQ-ESRVSKAVEVMIQHVENL 265
            D  Q    +K KL KS  ++  +  ++      +   + + ESR+ K ++      ENL
Sbjct: 162 RDLRQEVTTLKEKLHKSHTRYTEESNSKEKEIENLKNLVAEFESRLKKEIDSNDSVSENL 221

Query: 266 KRMYAKEHAELEELKQVLLQNERSFNPLEDDD 297
           ++   ++  EL+ +     Q    FN  ++++
Sbjct: 222 RKEMEQKSDELKRVMLAQTQLIEQFNQSQEEN 253


>gi|109255236 centrosomal protein 63 isoform d [Homo sapiens]
          Length = 475

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 50/222 (22%), Positives = 101/222 (45%), Gaps = 21/222 (9%)

Query: 109 EEPETIEE---HKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGF 165
           E+ E I+    ++K+      + S   +  + S   R ++   ANE E+E   +R++   
Sbjct: 179 EQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLV 238

Query: 166 KCDWFTLEKRVKLEERSRDLAE--ENLKKEITNCLKLLESLTPLCEDDNQAQEIIKKLEK 223
                 L+++ + EE+ R+  +  E L++E       L+S   L  +    +E   KL++
Sbjct: 239 GTSMTVLQEQQQKEEKLRESEKLLEALQEEKRELKAALQSQENLIHEARIQKE---KLQE 295

Query: 224 SIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEH---AELEELK 280
            +K     A       E +   +  +   +  + +++  E LKRM A  +   AE+++LK
Sbjct: 296 KVK-----ATNTQHAVEAISLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLK 350

Query: 281 QVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLRRVTIAS 322
           + +LQ E+S++   +    +I   +  L+      R +TIAS
Sbjct: 351 EQILQGEQSYSSALEGMKMEISHLTQELHQ-----RDITIAS 387


>gi|109255226 centrosomal protein 63 isoform c [Homo sapiens]
          Length = 495

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 50/222 (22%), Positives = 101/222 (45%), Gaps = 21/222 (9%)

Query: 109 EEPETIEE---HKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGF 165
           E+ E I+    ++K+      + S   +  + S   R ++   ANE E+E   +R++   
Sbjct: 179 EQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLV 238

Query: 166 KCDWFTLEKRVKLEERSRDLAE--ENLKKEITNCLKLLESLTPLCEDDNQAQEIIKKLEK 223
                 L+++ + EE+ R+  +  E L++E       L+S   L  +    +E   KL++
Sbjct: 239 GTSMTVLQEQQQKEEKLRESEKLLEALQEEKRELKAALQSQENLIHEARIQKE---KLQE 295

Query: 224 SIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEH---AELEELK 280
            +K     A       E +   +  +   +  + +++  E LKRM A  +   AE+++LK
Sbjct: 296 KVK-----ATNTQHAVEAISLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLK 350

Query: 281 QVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLRRVTIAS 322
           + +LQ E+S++   +    +I   +  L+      R +TIAS
Sbjct: 351 EQILQGEQSYSSALEGMKMEISHLTQELHQ-----RDITIAS 387


>gi|32528293 ecto-NOX disulfide-thiol exchanger 2 isoform a [Homo
           sapiens]
          Length = 581

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 52/228 (22%), Positives = 101/228 (44%), Gaps = 13/228 (5%)

Query: 93  QDSTSKDKTILNLEAKEEP--ETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSEN--TS 148
           Q + S  + ++N +A  E   E  +E  K+  SG  +     V    S + +++ +  T 
Sbjct: 265 QSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTK 324

Query: 149 ANEKEV-----EAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLES 203
           A  K +     +AE +R       D     +R +  E S D  EE  + + T    L+  
Sbjct: 325 AQRKNISVWCKQAEEIR---NIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQ 381

Query: 204 LTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVE 263
              L E+++  +  +      ++ L Q   +V  R +      Q   + +A++ M QH+ 
Sbjct: 382 AEALKEENDSLRWQLDAYRNEVELLKQEQGKV-HREDDPNKEQQLKLLQQALQGMQQHLL 440

Query: 264 NLKRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSK 311
            ++  Y K+ AELE+LK   LQ E+    L++ + C  +  +++ +S+
Sbjct: 441 KVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSE 488


>gi|32528291 ecto-NOX disulfide-thiol exchanger 2 isoform b [Homo
           sapiens]
          Length = 610

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 52/228 (22%), Positives = 101/228 (44%), Gaps = 13/228 (5%)

Query: 93  QDSTSKDKTILNLEAKEEP--ETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSEN--TS 148
           Q + S  + ++N +A  E   E  +E  K+  SG  +     V    S + +++ +  T 
Sbjct: 294 QSANSHVRRLVNEKAAHEKDMEEAKEKFKQALSGILIQFEQIVAVYHSASKQKAWDHFTK 353

Query: 149 ANEKEV-----EAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLES 203
           A  K +     +AE +R       D     +R +  E S D  EE  + + T    L+  
Sbjct: 354 AQRKNISVWCKQAEEIR---NIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQ 410

Query: 204 LTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVE 263
              L E+++  +  +      ++ L Q   +V  R +      Q   + +A++ M QH+ 
Sbjct: 411 AEALKEENDSLRWQLDAYRNEVELLKQEQGKV-HREDDPNKEQQLKLLQQALQGMQQHLL 469

Query: 264 NLKRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSK 311
            ++  Y K+ AELE+LK   LQ E+    L++ + C  +  +++ +S+
Sbjct: 470 KVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSE 517


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 61/303 (20%), Positives = 122/303 (40%), Gaps = 25/303 (8%)

Query: 33  RHTSSTDGTITSSDPGLEILNMASCDLDRNSLCKKE----EDTRSASPTIEAQGTSPA-- 86
           +H      ++T+ +    IL     D  R  L +KE    + T+      E +GT     
Sbjct: 501 QHIEVLKESLTAKEQRAAILQ-TEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEI 559

Query: 87  HDNIAFQDSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSEN 146
           HD     D   +   +L  + +   E + + +K+ +S    V  L   T  +     +  
Sbjct: 560 HDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLE 619

Query: 147 TSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAE---------ENLKKEITNC 197
            +  EKE   E L+       D    EK+ +++   +DL +          +L ++  + 
Sbjct: 620 EALAEKERTIERLKEQR----DRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASL 675

Query: 198 LKLLESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEV 257
           L L E  + L     +    +K LE +++   +   ++ S+ +       E+R S  +  
Sbjct: 676 LDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSD 735

Query: 258 MIQHVENLKRMY----AKEHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPS 313
            IQH+E     Y    +K  AE++ L ++L + E   N  +D    +++++    N K +
Sbjct: 736 RIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKND-KDKKIAELERQVKDQNKKVA 794

Query: 314 SLR 316
           +L+
Sbjct: 795 NLK 797


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 61/303 (20%), Positives = 122/303 (40%), Gaps = 25/303 (8%)

Query: 33  RHTSSTDGTITSSDPGLEILNMASCDLDRNSLCKKE----EDTRSASPTIEAQGTSPA-- 86
           +H      ++T+ +    IL     D  R  L +KE    + T+      E +GT     
Sbjct: 473 QHIEVLKESLTAKEQRAAILQ-TEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEI 531

Query: 87  HDNIAFQDSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSEN 146
           HD     D   +   +L  + +   E + + +K+ +S    V  L   T  +     +  
Sbjct: 532 HDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLE 591

Query: 147 TSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAE---------ENLKKEITNC 197
            +  EKE   E L+       D    EK+ +++   +DL +          +L ++  + 
Sbjct: 592 EALAEKERTIERLKEQR----DRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASL 647

Query: 198 LKLLESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEV 257
           L L E  + L     +    +K LE +++   +   ++ S+ +       E+R S  +  
Sbjct: 648 LDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSD 707

Query: 258 MIQHVENLKRMY----AKEHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPS 313
            IQH+E     Y    +K  AE++ L ++L + E   N  +D    +++++    N K +
Sbjct: 708 RIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKND-KDKKIAELERQVKDQNKKVA 766

Query: 314 SLR 316
           +L+
Sbjct: 767 NLK 769


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 71/318 (22%), Positives = 130/318 (40%), Gaps = 45/318 (14%)

Query: 98  KDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAE 157
           K+  +L  +  E+ + I          D+  S L  T  K ++L      S+  K  E +
Sbjct: 697 KELEVLQAKCNEQTKVI----------DNFTSQLKATEEKLLDLDALRKASSEGKS-EMK 745

Query: 158 FLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLE-SLTPLCEDDNQAQE 216
            LR  L         EK++K  E  ++ AE +    IT  L+  E  LT L E+ ++  +
Sbjct: 746 KLRQQLE------AAEKQIKHLEIEKN-AESSKASSITRELQGRELKLTNLQENLSEVSQ 798

Query: 217 IIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAEL 276
           + + LEK ++ L +  A  +  A           V ++++  +  +   +  +    ++L
Sbjct: 799 VKETLEKELQILKEKFAEASEEA---------VSVQRSMQETVNKLHQKEEQFNMLSSDL 849

Query: 277 EELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLRRVTIASLPRNIG-NAGMVAG 335
           E+L++ L   E  F   ++ ++  IK +    N          IA + +  G N+  +  
Sbjct: 850 EKLRENLADMEAKFREKDEREEQLIKAKEKLEND---------IAEIMKMSGDNSSQLTK 900

Query: 336 MENNDRFSRRS-SSWRILGSKQSEHRPSLPRFISTYSWADAEEEKCELKTKDDSEPSGEE 394
           M +  R   R     ++  +K +E+   L + I   +   AE+ + E   K +     EE
Sbjct: 901 MNDELRLKERDVEELQLKLTKANENASFLQKSIEDMT-VKAEQSQQEAAKKHE-----EE 954

Query: 395 TVERTRKPSLSEKKNNPS 412
             E  RK S  EKK   S
Sbjct: 955 KKELERKLSDLEKKMETS 972



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 83/430 (19%), Positives = 168/430 (39%), Gaps = 76/430 (17%)

Query: 62   NSLCKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKDKTILNLEAKEEPETIEEHKKEH 121
            N L +KEE     S  +E    + A     F++   +++ ++  + K E +  E  K   
Sbjct: 833  NKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSG 892

Query: 122  ASGDSVVSPLPVTTVKSVNLR--QSENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLE 179
             +   +        +K  ++   Q + T ANE    A FL+ S+    +  T++     +
Sbjct: 893  DNSSQLTKMNDELRLKERDVEELQLKLTKANEN---ASFLQKSI----EDMTVKAEQSQQ 945

Query: 180  ERSRDLAEEN--LKKEITNCLKLLESLTPLCED------------DNQAQEIIKKLEKSI 225
            E ++   EE   L++++++  K +E+    C++              + +EI++ L+K++
Sbjct: 946  EAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTL 1005

Query: 226  KFLSQCAARVASRAEMLGAINQESRVSK-------------AVEVMIQ----------HV 262
              L        +R E  G + +   + K             A+++M Q           +
Sbjct: 1006 --LDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASL 1063

Query: 263  ENLKRMYAKEHAELEELKQVLLQNERSFN------PLEDDDDCQIKKRSASLNSKPSSLR 316
            E+ K+  AK   EL+ LK+  L+N    N       +E+    + +K   +L    +   
Sbjct: 1064 EDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKS 1123

Query: 317  RVTIASLPRNIGNAGMVAGMENNDRFSRRSSSWR-ILGSKQSEHRPSLPRFISTYSWADA 375
            +   A    N+  A  +    +     ++    R +L ++  E +    +FI      DA
Sbjct: 1124 QQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIK-----DA 1178

Query: 376  EEEKCELK----------TKDDSEPSGEETVERTRKPSLSEKKNNPSKWDVSSVYDTIAS 425
            +EEK  L+          T+ D+E      +E+ R      +  N S   + SV  T+ S
Sbjct: 1179 DEEKASLQKSISITSALLTEKDAE------LEKLRNEVTVLRGENASAKSLHSVVQTLES 1232

Query: 426  WATNLKSSIR 435
                L+  ++
Sbjct: 1233 DKVKLELKVK 1242


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 71/318 (22%), Positives = 130/318 (40%), Gaps = 45/318 (14%)

Query: 98   KDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAE 157
            K+  +L  +  E+ + I          D+  S L  T  K ++L      S+  K  E +
Sbjct: 732  KELEVLQAKCNEQTKVI----------DNFTSQLKATEEKLLDLDALRKASSEGKS-EMK 780

Query: 158  FLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLE-SLTPLCEDDNQAQE 216
             LR  L         EK++K  E  ++ AE +    IT  L+  E  LT L E+ ++  +
Sbjct: 781  KLRQQLE------AAEKQIKHLEIEKN-AESSKASSITRELQGRELKLTNLQENLSEVSQ 833

Query: 217  IIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAEL 276
            + + LEK ++ L +  A  +  A           V ++++  +  +   +  +    ++L
Sbjct: 834  VKETLEKELQILKEKFAEASEEA---------VSVQRSMQETVNKLHQKEEQFNMLSSDL 884

Query: 277  EELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLRRVTIASLPRNIG-NAGMVAG 335
            E+L++ L   E  F   ++ ++  IK +    N          IA + +  G N+  +  
Sbjct: 885  EKLRENLADMEAKFREKDEREEQLIKAKEKLEND---------IAEIMKMSGDNSSQLTK 935

Query: 336  MENNDRFSRRS-SSWRILGSKQSEHRPSLPRFISTYSWADAEEEKCELKTKDDSEPSGEE 394
            M +  R   R     ++  +K +E+   L + I   +   AE+ + E   K +     EE
Sbjct: 936  MNDELRLKERDVEELQLKLTKANENASFLQKSIEDMT-VKAEQSQQEAAKKHE-----EE 989

Query: 395  TVERTRKPSLSEKKNNPS 412
              E  RK S  EKK   S
Sbjct: 990  KKELERKLSDLEKKMETS 1007



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 83/430 (19%), Positives = 168/430 (39%), Gaps = 76/430 (17%)

Query: 62   NSLCKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKDKTILNLEAKEEPETIEEHKKEH 121
            N L +KEE     S  +E    + A     F++   +++ ++  + K E +  E  K   
Sbjct: 868  NKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSG 927

Query: 122  ASGDSVVSPLPVTTVKSVNLR--QSENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLE 179
             +   +        +K  ++   Q + T ANE    A FL+ S+    +  T++     +
Sbjct: 928  DNSSQLTKMNDELRLKERDVEELQLKLTKANEN---ASFLQKSI----EDMTVKAEQSQQ 980

Query: 180  ERSRDLAEEN--LKKEITNCLKLLESLTPLCED------------DNQAQEIIKKLEKSI 225
            E ++   EE   L++++++  K +E+    C++              + +EI++ L+K++
Sbjct: 981  EAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTL 1040

Query: 226  KFLSQCAARVASRAEMLGAINQESRVSK-------------AVEVMIQ----------HV 262
              L        +R E  G + +   + K             A+++M Q           +
Sbjct: 1041 --LDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASL 1098

Query: 263  ENLKRMYAKEHAELEELKQVLLQNERSFN------PLEDDDDCQIKKRSASLNSKPSSLR 316
            E+ K+  AK   EL+ LK+  L+N    N       +E+    + +K   +L    +   
Sbjct: 1099 EDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKS 1158

Query: 317  RVTIASLPRNIGNAGMVAGMENNDRFSRRSSSWR-ILGSKQSEHRPSLPRFISTYSWADA 375
            +   A    N+  A  +    +     ++    R +L ++  E +    +FI      DA
Sbjct: 1159 QQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIK-----DA 1213

Query: 376  EEEKCELK----------TKDDSEPSGEETVERTRKPSLSEKKNNPSKWDVSSVYDTIAS 425
            +EEK  L+          T+ D+E      +E+ R      +  N S   + SV  T+ S
Sbjct: 1214 DEEKASLQKSISITSALLTEKDAE------LEKLRNEVTVLRGENASAKSLHSVVQTLES 1267

Query: 426  WATNLKSSIR 435
                L+  ++
Sbjct: 1268 DKVKLELKVK 1277


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 78/392 (19%), Positives = 137/392 (34%), Gaps = 41/392 (10%)

Query: 39  DGTITSSDPGLEILNMASCDLDRNSLCKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSK 98
           D TIT +   L    M + D   N   +KEE + S     E + T     +  +Q +  +
Sbjct: 122 DPTITDASLSLPSRRMQN-DTAENETTEKEEKSESRQERYEIEETETVTKS--YQKNDWR 178

Query: 99  DKTILNLEAKEEPETIEEHKKEHASGDSVVSPLP------------VTTVKSVNLRQSEN 146
           D      E KE+ E  EE  K  + G++ V  +             V ++K+  +   E 
Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238

Query: 147 TSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAE-ENLKKEITNCLKLLESLT 205
               E+E  ++              +    K+EE  ++ AE E  + E     ++     
Sbjct: 239 KQEEEREQGSD-------------EISHHEKMEEEDKERAEAERARLEAEERERIKAEQD 285

Query: 206 PLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVS----KAVEVMIQH 261
               D+    E  +K     +   +   R   R E   A  +  R+     +A E   + 
Sbjct: 286 KKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRI 345

Query: 262 VENLKRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLRRVTIA 321
            E  KR   +     EE K+   + +R+    E+    + +KR+  L  K  +++   I 
Sbjct: 346 KEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIK 405

Query: 322 S--LPRNIGNAGMVAGMENNDRFSRR--SSSWRILGSKQSEHRPSLPRFISTYSWADAEE 377
              + + I    +       D+             G+K    R  L     T+   + ++
Sbjct: 406 GEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKD 465

Query: 378 EKCELKTKDDSEPSGEETVERTRKPSLSEKKN 409
           EK     K D EP  E      RK   +E K+
Sbjct: 466 EKI----KKDKEPKEEVKSFMDRKKGFTEVKS 493


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 58/238 (24%), Positives = 105/238 (44%), Gaps = 30/238 (12%)

Query: 93   QDSTSKDKTILNLEAKEEPETI---EEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSA 149
            Q    + K + NL ++EE E I   EE+KK     + ++  L   T+K  N++Q     +
Sbjct: 2404 QQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLK--TIKKENIQQKAQLDS 2461

Query: 150  NEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESLTPLCE 209
              K +       SL    D    + + +LEER   +    L+K+        + +     
Sbjct: 2462 FVKSMS------SLQNDRDRIVGDYQ-QLEERHLSII---LEKD--------QLIQEAAA 2503

Query: 210  DDNQAQEIIKKLEKSIKFLSQCAARV-ASRAEMLGAINQ-----ESRVSKAVEVMIQHVE 263
            ++N+ +E I+ L   +  L+   A++ A   +    +NQ     +S+  + +EV +Q  +
Sbjct: 2504 ENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNK 2563

Query: 264  NLKRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLRRVTIA 321
             L+  YAK   +L+E ++      RSFN L+++    + K   SL    S L R   A
Sbjct: 2564 ELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQ-DLSKEIESLKVSISQLTRQVTA 2620



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 54/254 (21%), Positives = 97/254 (38%), Gaps = 18/254 (7%)

Query: 87  HDNIAFQDSTSKD-KTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSE 145
           H++   Q  T  D +T +  + +     +EEH++       VV  L      +    Q  
Sbjct: 233 HEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQIL 292

Query: 146 NTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESLT 205
           +    + E E   LR ++  + +    E ++ LE+   ++AE  L         L E + 
Sbjct: 293 SQQLQQMEAEHNTLRNTVETERE----ESKILLEKMELEVAERKLSFH-----NLQEEMH 343

Query: 206 PLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENL 265
            L E   QA +   +LE     L Q       +AEM    +    + K  + +    + L
Sbjct: 344 HLLEQFEQAGQAQAELESRYSALEQ-----KHKAEMEEKTSHILSLQKTGQELQSACDAL 398

Query: 266 KRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLRRVTIASLPR 325
           K   +K    L++  +  +Q+ ++   LED    + K+ S  LN  P         +   
Sbjct: 399 KDQNSKL---LQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFP 455

Query: 326 NIGNAGMVAGMENN 339
           ++ N G  A  E N
Sbjct: 456 DVYNEGTQAVTEEN 469


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 39/183 (21%), Positives = 88/183 (48%), Gaps = 16/183 (8%)

Query: 145  ENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESL 204
            E   A+ +  E + LR  L F      +E+++  ++   + A+ N  + + +    L++ 
Sbjct: 1545 EEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAE 1604

Query: 205  TPLCEDDNQAQEIIKKLEKSIKFL-------SQCAARVASRAEMLGAINQESRVS----- 252
            T      N+A  + KK+E  +  +       ++ AA    + + L ++ +++++      
Sbjct: 1605 T---RSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 1661

Query: 253  KAVEVMIQHVENLKRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKP 312
            +A + + +++  ++R      AELEEL+ V+ Q ERS   L + +  +  +R   L+S+ 
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS-RKLAEQELIETSERVQLLHSQN 1720

Query: 313  SSL 315
            +SL
Sbjct: 1721 TSL 1723


>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
          Length = 558

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 3/79 (3%)

Query: 145 ENTSANEKEVEAEFLRLSLGFKCDWF---TLEKRVKLEERSRDLAEENLKKEITNCLKLL 201
           +N  A EK+V+ E   L + F  +     TLEK++ +E+++R + ++ LKKE     KL 
Sbjct: 434 DNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQ 493

Query: 202 ESLTPLCEDDNQAQEIIKK 220
           E+L    +   QA++ +K+
Sbjct: 494 EALEFETKRREQAEQTLKQ 512


>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
          Length = 706

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 3/79 (3%)

Query: 145 ENTSANEKEVEAEFLRLSLGFKCDWF---TLEKRVKLEERSRDLAEENLKKEITNCLKLL 201
           +N  A EK+V+ E   L + F  +     TLEK++ +E+++R + ++ LKKE     KL 
Sbjct: 582 DNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQ 641

Query: 202 ESLTPLCEDDNQAQEIIKK 220
           E+L    +   QA++ +K+
Sbjct: 642 EALEFETKRREQAEQTLKQ 660


>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
          Length = 504

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 3/79 (3%)

Query: 145 ENTSANEKEVEAEFLRLSLGFKCDWF---TLEKRVKLEERSRDLAEENLKKEITNCLKLL 201
           +N  A EK+V+ E   L + F  +     TLEK++ +E+++R + ++ LKKE     KL 
Sbjct: 380 DNARAQEKQVQLEKTELKMDFLRERELRETLEKQLAMEQKNRAIVQKRLKKEKKAKRKLQ 439

Query: 202 ESLTPLCEDDNQAQEIIKK 220
           E+L    +   QA++ +K+
Sbjct: 440 EALEFETKRREQAEQTLKQ 458


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 45/181 (24%), Positives = 86/181 (47%), Gaps = 16/181 (8%)

Query: 139 VNLRQSENT-SANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNC 197
           VN +  E T   NE + E E LR     K    TLE+ V+  +   +L E+ +K++  + 
Sbjct: 710 VNSKSEEMTLQINELQKEIEILRQEEKEKG---TLEQEVQELQLKTELLEKQMKEKEND- 765

Query: 198 LKLLESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVS---KA 254
             L E    L  +++  ++  K LE  +K  +  +     R   L +I  +S+ S   K 
Sbjct: 766 --LQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQE--ERLIFLDSIKSKSKDSVWEKE 821

Query: 255 VEVMIQHVENLKRMYAKEHAELEELKQVLLQNERSF----NPLEDDDDCQIKKRSASLNS 310
           +E++I+  E+LK+   + + E+E+ +      E++F      L+++  C +K +    +S
Sbjct: 822 IEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDS 881

Query: 311 K 311
           K
Sbjct: 882 K 882



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 68/331 (20%), Positives = 137/331 (41%), Gaps = 68/331 (20%)

Query: 42   ITSSDPGLEILNMASCDLDRNSLCKKEEDTRSASPTIEAQGT----SPAHDNIAFQ---- 93
            I+ +   LE   +   +L R S  +K+E T S     E +      S A + +A +    
Sbjct: 1861 ISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKA 1920

Query: 94   ----DSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLP-----VTTVKSVNLRQS 144
                D  + +KT+   + +E+ + I+  ++E     + +  L      +   + +  RQ 
Sbjct: 1921 EGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQK 1980

Query: 145  ENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEE------NLKKEITNCL 198
            E   A    VE + L+ +     +   LE + + E+   DL ++      +++++++  +
Sbjct: 1981 EAMKAEAGPVEQQLLQETEKLMKE--KLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFI 2038

Query: 199  KL-LESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEM----LGAINQESRV-- 251
            +L  E  T L +   Q Q + K+LEK  KFL + A       ++    +  + Q+ +V  
Sbjct: 2039 ELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVP 2098

Query: 252  ---------SKAVEVMIQHV--------------ENLKRMYAKEHAELE-------ELKQ 281
                     ++ VE +  H+              E L+R   + + E+E       EL+Q
Sbjct: 2099 RFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQ 2158

Query: 282  VLLQNERSFNPLEDDDDCQIKKRSASLNSKP 312
             LL +  +F  +ED      +K   ++ +KP
Sbjct: 2159 ALLVSADTFQKVED------RKHFGAVEAKP 2183



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 38/134 (28%), Positives = 58/134 (43%), Gaps = 12/134 (8%)

Query: 90   IAFQDSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSA 149
            IA ++   K+K +L L+   E    ++ +KE       V  L  TT     L  S   S 
Sbjct: 2631 IAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTT----ELFHSNEESG 2686

Query: 150  NEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESLTPLCE 209
               E+EA  LR          T  +    +E++  L EE L KE TN   L + L+ + +
Sbjct: 2687 FFNELEA--LRAE-----SVATKAELASYKEKAEKLQEELLVKE-TNMTSLQKDLSQVRD 2738

Query: 210  DDNQAQEIIKKLEK 223
               +A+E +  LEK
Sbjct: 2739 HLAEAKEKLSILEK 2752


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 45/181 (24%), Positives = 86/181 (47%), Gaps = 16/181 (8%)

Query: 139 VNLRQSENT-SANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNC 197
           VN +  E T   NE + E E LR     K    TLE+ V+  +   +L E+ +K++  + 
Sbjct: 710 VNSKSEEMTLQINELQKEIEILRQEEKEKG---TLEQEVQELQLKTELLEKQMKEKEND- 765

Query: 198 LKLLESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVS---KA 254
             L E    L  +++  ++  K LE  +K  +  +     R   L +I  +S+ S   K 
Sbjct: 766 --LQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQE--ERLIFLDSIKSKSKDSVWEKE 821

Query: 255 VEVMIQHVENLKRMYAKEHAELEELKQVLLQNERSF----NPLEDDDDCQIKKRSASLNS 310
           +E++I+  E+LK+   + + E+E+ +      E++F      L+++  C +K +    +S
Sbjct: 822 IEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDS 881

Query: 311 K 311
           K
Sbjct: 882 K 882



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 47/215 (21%), Positives = 94/215 (43%), Gaps = 26/215 (12%)

Query: 42   ITSSDPGLEILNMASCDLDRNSLCKKEEDTRSASPTIEAQGT----SPAHDNIAFQ---- 93
            I+ +   LE   +   +L R S  +K+E T S     E +      S A + +A +    
Sbjct: 1861 ISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKA 1920

Query: 94   ----DSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLP-----VTTVKSVNLRQS 144
                D  + +KT+   + +E+ + I+  ++E     + +  L      +   + +  RQ 
Sbjct: 1921 EGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQK 1980

Query: 145  ENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEE------NLKKEITNCL 198
            E   A    VE + L+ +     +   LE + + E+   DL ++      +++++++  +
Sbjct: 1981 EAMKAEAGPVEQQLLQETEKLMKE--KLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFI 2038

Query: 199  KL-LESLTPLCEDDNQAQEIIKKLEKSIKFLSQCA 232
            +L  E  T L +   Q Q + K+LEK  KFL + A
Sbjct: 2039 ELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQA 2073



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 38/134 (28%), Positives = 58/134 (43%), Gaps = 12/134 (8%)

Query: 90   IAFQDSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSA 149
            IA ++   K+K +L L+   E    ++ +KE       V  L  TT     L  S   S 
Sbjct: 2623 IAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTT----ELFHSNEESG 2678

Query: 150  NEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESLTPLCE 209
               E+EA  LR          T  +    +E++  L EE L KE TN   L + L+ + +
Sbjct: 2679 FFNELEA--LRAE-----SVATKAELASYKEKAEKLQEELLVKE-TNMTSLQKDLSQVRD 2730

Query: 210  DDNQAQEIIKKLEK 223
               +A+E +  LEK
Sbjct: 2731 HLAEAKEKLSILEK 2744


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 45/227 (19%), Positives = 95/227 (41%), Gaps = 24/227 (10%)

Query: 98  KDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAE 157
           K++T L  E     E  +E+ K                 +  N+      +  EKE    
Sbjct: 149 KERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADR 208

Query: 158 FLRLS-----LGFKCDWFTL-EKRVKLEERSRDLAEENLKKEITNCLKLLESLTPLCEDD 211
           + RL         +   F L    V++E+ +++LA +N  KEI    K ++ +    ++ 
Sbjct: 209 YQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKN--KEIEKDKKRMDKVEDELKEK 266

Query: 212 N--------QAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVE 263
                    + Q+I K++++    L+Q       R + + A    S   K +E   + ++
Sbjct: 267 KKELGKMMREQQQIEKEIKEKDSELNQ------KRPQYIKAKENTSHKIKKLEAAKKSLQ 320

Query: 264 NLKRMYAKEHAELEELKQVLLQNERSFNPLED--DDDCQIKKRSASL 308
           N ++ Y K   +++EL++ +L  E++    E+  +++ Q + R  +L
Sbjct: 321 NAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTL 367



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 45/203 (22%), Positives = 85/203 (41%), Gaps = 21/203 (10%)

Query: 108  KEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGFKC 167
            K++   IE+ KKE      ++           N   ++ +  N+K  E E +R  LG   
Sbjct: 843  KKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGAN 902

Query: 168  DWFT-LEKRV-----KLEERSRDLAEENLKKEITNCLKLLESLTPLCE---DDNQAQEII 218
               T L+K V     KLE++  D      +  +    K+ +   PL +   DD   +E  
Sbjct: 903  KEMTHLQKEVTAIETKLEQKRSD------RHNLLQACKMQDIKLPLSKGTMDDISQEEGS 956

Query: 219  KKLEKSI---KFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAE 275
             + E S+   + +S   AR A      G + ++ + ++A E + Q +  L++   K + +
Sbjct: 957  SQGEDSVSGSQRISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQ---KLNEQ 1013

Query: 276  LEELKQVLLQNERSFNPLEDDDD 298
               L+++   N ++   LE   D
Sbjct: 1014 QSVLQRIAAPNMKAMEKLESVRD 1036


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 47/225 (20%), Positives = 99/225 (44%), Gaps = 20/225 (8%)

Query: 93   QDSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEK 152
            ++S  K+   L + A  E +  +  + EH         L +  +++ N+R ++    N +
Sbjct: 1621 KESQEKEYQFLKMTAVNETQE-KMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLE 1679

Query: 153  EVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESLTPLCEDDN 212
            E     +R     + D  ++E+ +K+E   RD  +ENL++ IT  L+  E L  +     
Sbjct: 1680 E-----MRSVTKERDDLRSVEETLKVE---RDQLKENLRETITRDLEKQEELKIVHMHLK 1731

Query: 213  QAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKE 272
            + QE I KL   +      + +    + M   +   +   KA ++ IQ    +  M+ KE
Sbjct: 1732 EHQETIDKLRGIV------SEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKE 1785

Query: 273  HAE-LEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLR 316
              E +++L+ ++ +     + ++ D    ++  +A L  K   L+
Sbjct: 1786 QQETIDKLRGIVSEKTDKLSNMQKD----LENSNAKLQEKIQELK 1826



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 55/245 (22%), Positives = 101/245 (41%), Gaps = 48/245 (19%)

Query: 63   SLCKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKDKTILNLE------AKEEPETIEE 116
            SL  KE+D  +     E +   P            KD  +L +E      +K   E+ +E
Sbjct: 1389 SLNMKEKDNETTKIVSEMEQFKP------------KDSALLRIEIEMLGLSKRLQESHDE 1436

Query: 117  HKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGFKCDWFTL-EKR 175
             K      D +        ++ V   +S+    N KE+ A+ L      K     L E+ 
Sbjct: 1437 MKSVAKEKDDL------QRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQE 1490

Query: 176  VKLEERSRDLAEENLKKEITNCLKLLESLTPLCEDDNQAQEIIKKLEK-SIKFLSQCAAR 234
              + E   +L+E+  + EI+   K LE++    +  N+ QEI +K E+ +IK +S+   +
Sbjct: 1491 ETINELRVNLSEK--ETEISTIQKQLEAINDKLQ--NKIQEIYEKEEQFNIKQISEVQEK 1546

Query: 235  V------------------ASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAEL 276
            V                  +  ++ML   N+     + +++MI+  E +KR+      E 
Sbjct: 1547 VNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIER 1606

Query: 277  EELKQ 281
            ++LK+
Sbjct: 1607 DQLKE 1611



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 58/242 (23%), Positives = 114/242 (47%), Gaps = 26/242 (10%)

Query: 86   AHDNIAFQD-STSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQS 144
            ++D +  QD    ++  I ++  KE+ ETI++ +        +VS     T K  N+++ 
Sbjct: 1761 SNDALKAQDLKIQEELRIAHMHLKEQQETIDKLR-------GIVSE---KTDKLSNMQKD 1810

Query: 145  ENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAE-ENLKKEITNCLKLLES 203
               S  + + + + L+ +   +    TL+K V   E  + ++E E LKK+I +    L  
Sbjct: 1811 LENSNAKLQEKIQELKAN---EHQLITLKKDVN--ETQKKVSEMEQLKKQIKDQSLTLSK 1865

Query: 204  LTPLCEDDNQAQEIIKKLE--KSIKFLSQCAARVASRAEM-LGAINQESRVSKAVEVMIQ 260
            L    E+ N AQ++ + LE  KS+        RV    ++    + +  + +KA ++ IQ
Sbjct: 1866 LE--IENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQ 1923

Query: 261  HVENLKRMYAKEHAE-LEELKQVLLQNERSFNPLEDDDD---CQIKKRSASLNSKPSSLR 316
                  RM +KEH E +++L++ + +     + ++ D D    +++K+   L  K   L 
Sbjct: 1924 QELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLL 1983

Query: 317  RV 318
            RV
Sbjct: 1984 RV 1985


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 38/183 (20%), Positives = 88/183 (48%), Gaps = 16/183 (8%)

Query: 145  ENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESL 204
            E   A+ +  E + LR  L F      +E+++  ++   + A+ N ++ + +    L++ 
Sbjct: 1547 EEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAE 1606

Query: 205  TPLCEDDNQAQEIIKKLEKSIKFL-------SQCAARVASRAEMLGAINQESRVS----- 252
            T      N+   + KK+E  +  +       ++ AA    + + L ++ +++++      
Sbjct: 1607 T---RSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 1663

Query: 253  KAVEVMIQHVENLKRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKP 312
            +A + + +++  ++R      AELEEL+ V+ Q ERS   L + +  +  +R   L+S+ 
Sbjct: 1664 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS-RKLAEQELIETSERVQLLHSQN 1722

Query: 313  SSL 315
            +SL
Sbjct: 1723 TSL 1725



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 71/346 (20%), Positives = 135/346 (39%), Gaps = 31/346 (8%)

Query: 66   KKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKD------KTILNLEAKEEPETIE-EHK 118
            K E + + A    E +     H  +     TS D        +L ++ K E +  E E +
Sbjct: 1571 KAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQ 1630

Query: 119  KEHASGDSVVSPLPVTTVKSV----NLRQSENTSANE--KEVEAEFLRLSLGFKCDWFTL 172
              HA+  +  +   V +++S+     ++  +   AN+  KE  A   R +   + +   L
Sbjct: 1631 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL 1690

Query: 173  EKRVKLEERSRDLAEENL-------------KKEITNCLKLLES-LTPL-CEDDNQAQEI 217
               V+  ERSR LAE+ L                + N  K +ES LT L  E +   QE 
Sbjct: 1691 RAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQEC 1750

Query: 218  IKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELE 277
                EK+ K ++  A       +         R+ K +E  I+ +++  R+   E   L+
Sbjct: 1751 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH--RLDEAEQIALK 1808

Query: 278  ELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLRRVTIASLPRNIGNAGMVAGME 337
              K+ L + E     LE + + + K+ + S+     S RR+   +         ++   +
Sbjct: 1809 GGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQD 1868

Query: 338  NNDRFSRRSSSWRILGSKQSEH-RPSLPRFISTYSWADAEEEKCEL 382
              D+   +  +++    +  E    +L +F       D  EE+ ++
Sbjct: 1869 LVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADI 1914


>gi|122937396 coiled-coil domain containing 150 [Homo sapiens]
          Length = 1101

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 54/278 (19%), Positives = 114/278 (41%), Gaps = 40/278 (14%)

Query: 56  SCDLDRNSLCKKEEDTRSASPTI---------EAQGTSPAHDNI-AFQDSTSKDKTILNL 105
           +C+   N +C+ E   +S    I           Q T+   D + A Q+  SKD  +L+L
Sbjct: 96  NCEFLVNRMCRLESLMQSLKMNIFRLQTEKDLNPQKTAFLKDRLNAIQEEHSKDLKLLHL 155

Query: 106 EAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGF 165
           E     + +   K+E       V  L  T    +  +  +N +  E+E++    +++L  
Sbjct: 156 EVMNLRQQLRAVKEEEDKAQDEVQRL--TATLKIASQTKKNAAIIEEELKTTKRKMNL-- 211

Query: 166 KCDWFTLEKRVKLEERSRDLAE-----ENLKKEITNCLKLLESLTPLCEDDNQAQEIIKK 220
                      K++E  R LA+     E+L+K  +  L  ++ +    E + +   I+++
Sbjct: 212 -----------KIQELRRQLAQEKYLRESLEKSASAMLLKIQEMGSTVEVERKQVHILQQ 260

Query: 221 ----LEKSIKFLSQCAARVASRAEMLGAINQESRV-----SKAVEVMIQHVENLKRMYAK 271
               L  SI+   +  A+   + E L     + +         +  +++  +NL+  + K
Sbjct: 261 NCIALRDSIQSAQELLAQEQKKKEELEIATSQLKSDLTSRDDLISKLVEENKNLQISFNK 320

Query: 272 EHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLN 309
           EH E   L+  ++    +    +  +D Q+ K+ + L+
Sbjct: 321 EHEENAYLRSEIMSLHEASEKAQVLND-QLTKKCSELS 357


>gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]
          Length = 939

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 53/228 (23%), Positives = 109/228 (47%), Gaps = 25/228 (10%)

Query: 82  GTSPAHDNIAFQDSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVN- 140
           G++    +   Q +T+  +T +     ++ ET+E+  +     D+V+ P  V     ++ 
Sbjct: 623 GSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVED--EIDVRNDAVILPSCVEAEAKIHE 680

Query: 141 LRQSENTSANEKEVEAEFLRLSLGF----------KCDWFTLEKRVKLEERSRDLAEENL 190
            +++ + SA++   + + LR  L            +C  FT + +V L++R  ++ ++ +
Sbjct: 681 TQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKV-LQQRILEMNDKYV 739

Query: 191 KKEI------TNCLKLLESLTPLCED-DNQAQEIIKKLEKSIKFLSQCAARVASRAEMLG 243
           KKE       T+ + LLES+    E  D+   +  + LE+  +   QC+A    +AE   
Sbjct: 740 KKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQ 799

Query: 244 AINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQ--VLLQNERS 289
             N ES+ S+  E+ +Q ++++ R   K   E ++ K    LL+ E+S
Sbjct: 800 CSNNESK-SEMDEMAVQ-LDDVFRQLDKCSIERDQYKSEVELLEMEKS 845


>gi|109134347 NY-REN-58 antigen [Homo sapiens]
          Length = 701

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 55/253 (21%), Positives = 103/253 (40%), Gaps = 38/253 (15%)

Query: 93  QDSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEK 152
           ++ T K+   + L+ +++  TIE  +KE      +   +    ++  +L QSEN   N  
Sbjct: 437 EEITRKELQSVRLKLQQQIVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSENDLLNSN 496

Query: 153 EVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESLTPLCEDDN 212
           ++  E +   L  +C  F  +      E  + L E+ + + +    KL E +T   E  N
Sbjct: 497 QMLKEMVE-RLKQECRNFRSQAEKAQLEAEKTLEEKQI-QWLEEKHKLHERITDREEKYN 554

Query: 213 QAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKE 272
           QA+E +++            A +A +       N+  R+ + VEV+    E         
Sbjct: 555 QAKEKLQR------------AAIAQKKRKSLHENKLKRLQEKVEVLEAKKE--------- 593

Query: 273 HAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLRRV--------TIASLP 324
             ELE   QVL +    F     +D  +++KR   +  + +  R +        T +  P
Sbjct: 594 --ELETENQVLNRQNVPF-----EDYTRLQKRLKDIQRRHNEFRSLILVPNMPPTASINP 646

Query: 325 RNIGNAGMVAGME 337
            +  ++ MV  ME
Sbjct: 647 VSFQSSAMVPSME 659


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.125    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,213,231
Number of Sequences: 37866
Number of extensions: 838437
Number of successful extensions: 3547
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 232
Number of HSP's that attempted gapping in prelim test: 3269
Number of HSP's gapped (non-prelim): 506
length of query: 499
length of database: 18,247,518
effective HSP length: 106
effective length of query: 393
effective length of database: 14,233,722
effective search space: 5593852746
effective search space used: 5593852746
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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