Search of human proteins with 42741655

Search of human proteins with 42741655

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42741655 met proto-oncogene isoform b precursor [Homo
sapiens]
         (1390 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]    2830   0.0  
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]   2818   0.0  
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s...   720   0.0  
gi|66932918 MER receptor tyrosine kinase precursor [Homo sapiens]     244   5e-64
gi|21536468 AXL receptor tyrosine kinase isoform 2 [Homo sapiens]     234   4e-61
gi|21536466 AXL receptor tyrosine kinase isoform 1 [Homo sapiens]     234   4e-61
gi|27597078 TYRO3 protein tyrosine kinase [Homo sapiens]              232   2e-60
gi|54607020 RYK receptor-like tyrosine kinase isoform 1 [Homo sa...   211   3e-54
gi|54607018 RYK receptor-like tyrosine kinase isoform 2 [Homo sa...   211   4e-54
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo...   211   5e-54
gi|119395738 insulin receptor isoform Short precursor [Homo sapi...   208   3e-53
gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]   208   3e-53
gi|19924165 proto-oncogene c-ros-1 protein precursor [Homo sapiens]   204   6e-52
gi|31657140 insulin receptor-related receptor precursor [Homo sa...   201   3e-51
gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homo...   199   2e-50
gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolo...   199   2e-50
gi|254028242 fibroblast growth factor receptor 3 isoform 3 precu...   198   3e-50
gi|4503711 fibroblast growth factor receptor 3 isoform 1 precurs...   198   3e-50
gi|13112048 fibroblast growth factor receptor 3 isoform 2 precur...   197   4e-50
gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]     195   3e-49
gi|13186236 fibroblast growth factor receptor 1 isoform 4 precur...   194   5e-49
gi|13186234 fibroblast growth factor receptor 1 isoform 3 precur...   194   5e-49
gi|13186251 fibroblast growth factor receptor 1 isoform 2 precur...   194   5e-49
gi|105990522 fibroblast growth factor receptor 1 isoform 1 precu...   194   5e-49
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a...   193   8e-49
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b...   193   8e-49
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]             193   8e-49
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]               193   8e-49
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]             193   8e-49
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]             193   8e-49

>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
          Length = 1390

 Score = 2830 bits (7335), Expect = 0.0
 Identities = 1390/1390 (100%), Positives = 1390/1390 (100%)

Query: 1    MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH 60
            MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
Sbjct: 1    MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH 60

Query: 61   HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL 120
            HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
Sbjct: 61   HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL 120

Query: 121  VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL 180
            VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
Sbjct: 121  VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL 180

Query: 181  GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE 240
            GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
Sbjct: 181  GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE 240

Query: 241  FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL 300
            FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
Sbjct: 241  FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL 300

Query: 301  TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS 360
            TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
Sbjct: 301  TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS 360

Query: 361  AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF 420
            AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
Sbjct: 361  AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF 420

Query: 421  TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL 480
            TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
Sbjct: 421  TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL 480

Query: 481  LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW 540
            LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
Sbjct: 481  LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW 540

Query: 541  CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK 600
            CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
Sbjct: 541  CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK 600

Query: 601  TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT 660
            TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
Sbjct: 601  TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT 660

Query: 661  SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF 720
            SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
Sbjct: 661  SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF 720

Query: 721  AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH 780
            AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH
Sbjct: 721  AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH 780

Query: 781  EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV 840
            EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV
Sbjct: 781  EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV 840

Query: 841  FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL 900
            FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL
Sbjct: 841  FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL 900

Query: 901  LKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQ 960
            LKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQ
Sbjct: 901  LKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQ 960

Query: 961  IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGS 1020
            IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGS
Sbjct: 961  IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGS 1020

Query: 1021 CRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF 1080
            CRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF
Sbjct: 1021 CRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF 1080

Query: 1081 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1140
            NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL
Sbjct: 1081 NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1140

Query: 1141 SLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF 1200
            SLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF
Sbjct: 1141 SLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF 1200

Query: 1201 VHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF 1260
            VHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
Sbjct: 1201 VHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF 1260

Query: 1261 TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW 1320
            TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW
Sbjct: 1261 TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW 1320

Query: 1321 HPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVD 1380
            HPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVD
Sbjct: 1321 HPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVD 1380

Query: 1381 TRPASFWETS 1390
            TRPASFWETS
Sbjct: 1381 TRPASFWETS 1390


>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
          Length = 1408

 Score = 2818 bits (7306), Expect = 0.0
 Identities = 1390/1408 (98%), Positives = 1390/1408 (98%), Gaps = 18/1408 (1%)

Query: 1    MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH 60
            MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH
Sbjct: 1    MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEH 60

Query: 61   HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL 120
            HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
Sbjct: 61   HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL 120

Query: 121  VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL 180
            VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
Sbjct: 121  VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL 180

Query: 181  GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE 240
            GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
Sbjct: 181  GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE 240

Query: 241  FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL 300
            FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
Sbjct: 241  FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL 300

Query: 301  TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS 360
            TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
Sbjct: 301  TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS 360

Query: 361  AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF 420
            AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
Sbjct: 361  AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF 420

Query: 421  TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL 480
            TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
Sbjct: 421  TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL 480

Query: 481  LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW 540
            LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
Sbjct: 481  LDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW 540

Query: 541  CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK 600
            CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK
Sbjct: 541  CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKK 600

Query: 601  TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT 660
            TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
Sbjct: 601  TRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT 660

Query: 661  SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF 720
            SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
Sbjct: 661  SISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF 720

Query: 721  AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFI------------------SGGSTITG 762
            AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFI                  SGGSTITG
Sbjct: 721  AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITG 780

Query: 763  VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM 822
            VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM
Sbjct: 781  VGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFM 840

Query: 823  LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC 882
            LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC
Sbjct: 841  LDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSC 900

Query: 883  ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS 942
            ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS
Sbjct: 901  ENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSIS 960

Query: 943  TALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVD 1002
            TALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVD
Sbjct: 961  TALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVD 1020

Query: 1003 YRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPEL 1062
            YRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPEL
Sbjct: 1021 YRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPEL 1080

Query: 1063 VQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVS 1122
            VQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVS
Sbjct: 1081 VQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVS 1140

Query: 1123 QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLI 1182
            QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLI
Sbjct: 1141 QFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLI 1200

Query: 1183 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTG 1242
            GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTG
Sbjct: 1201 GFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTG 1260

Query: 1243 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRL 1302
            AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRL
Sbjct: 1261 AKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRL 1320

Query: 1303 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCV 1362
            LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCV
Sbjct: 1321 LQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCV 1380

Query: 1363 APYPSLLSSEDNADDEVDTRPASFWETS 1390
            APYPSLLSSEDNADDEVDTRPASFWETS
Sbjct: 1381 APYPSLLSSEDNADDEVDTRPASFWETS 1408


>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
            sapiens]
          Length = 1400

 Score =  720 bits (1859), Expect = 0.0
 Identities = 482/1406 (34%), Positives = 710/1406 (50%), Gaps = 102/1406 (7%)

Query: 7    LAPGILVLLFTLVQRSNGE---CKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEHH-- 61
            L    L+LL    + + GE   C      +  + ++KY +P+F+A   +Q ++ +E    
Sbjct: 7    LPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVTYEGDRN 66

Query: 62   ---IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINM 118
               +F+   N ++VL   DL+ V    TGP  + P C  C  C    +   G   D    
Sbjct: 67   ESAVFVAIRNRLHVLGP-DLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPG---DTDTK 121

Query: 119  ALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVS 178
             LV+D      L+SCGS  +G C  H      TA   +   C+FS     P  CPDCV S
Sbjct: 122  VLVLDPALP-ALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDCPDCVAS 180

Query: 179  ALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFM--FLTDQSYID 236
             LG +V    + +   F+V ++++++        S+S+RRLK    GF   F+     + 
Sbjct: 181  PLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVA----LS 236

Query: 237  VLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFCSINSGLHSYMEM 294
            VLP+   SY I+YVH+F +  F+YFLTVQ  ++  D    HTR+ R  +    L  Y E+
Sbjct: 237  VLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPELGDYREL 296

Query: 295  PLECILTEKRKKRSTKK--EVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPD 352
             L+C    KR++R   +  + + +L+ A+ +  GAQLA ++  +   ++LFGVF   K  
Sbjct: 297  VLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVFVTGKDG 356

Query: 353  SAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFN----RTLLRNSSG 408
                   S +CAFPI    D  + ++++   RC +    P      +     +   N  G
Sbjct: 357  GPGVGPNSVVCAFPI----DLLDTLIDEGVERCCESPVHPGLRRGLDFFQSPSFCPNPPG 412

Query: 409  CEARRDE-----YRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFM 463
             EA         +    +++  RVDLF G    V +T++      ++T+A++GT +GR +
Sbjct: 413  LEALSPNTSCRHFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAHMGTMDGRIL 472

Query: 464  QVVVSRSGPSTPHV-NFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRH 522
            QV + RS     +V NF L     S + +         + L  +G ++ ++P+ G GCRH
Sbjct: 473  QVELVRSLNYLLYVSNFSLGD---SGQPVQRDVSRLGDHLLFASGDQVFQVPIQGPGCRH 529

Query: 523  FQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLT 582
            F +C +CL A  F+ CGWC + C + +EC  G+W Q  C P + +  P+S PL G TRLT
Sbjct: 530  FLTCGRCLRAWHFMGCGWCGNMCGQQKEC-PGSWQQDHCPPKLTEFHPHSGPLRGSTRLT 588

Query: 583  ICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSEST----------MNTLKCTVGPAMNK 632
            +CG +F    +        +V +G   C     +S+          +   +C + P   +
Sbjct: 589  LCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFECELEPLGTQ 648

Query: 633  HF---NMSIIISNG--------HGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNY 681
                 N+S+ ++N          GT+    FS+++PV+ ++ P +GP AGGT LTL G  
Sbjct: 649  AVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAGGTCLTLEGQS 708

Query: 682  LNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLANRETS-IFSYRE 740
            L+ G SR + + G  C L  VS   L C TP         + L++  A    S  F YRE
Sbjct: 709  LSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGGAQVPGSWTFQYRE 768

Query: 741  DPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIIC 800
            DP+V  I P   +I+  S IT  G++L S     +V++ H+  R     C+ R   E   
Sbjct: 769  DPVVLSISPNCGYIN--SHITICGQHLTSAW--HLVLSFHDGLRAVESRCE-RQLPEQQL 823

Query: 801  CTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENV-LE 859
            C  P     + Q  +        DG             P   P    V +      +  E
Sbjct: 824  CRLPEYVVRDPQGWVAGNLSARGDGAAGFTLPGFRFLPPPHPPSANLVPLKPEEHAIKFE 883

Query: 860  IKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTV 919
              G     + V G  + VG +SC++     + V+C +P  L        ++        +
Sbjct: 884  YIGLGAVADCV-GINVTVGGESCQH-EFRGDMVVCPLPPSLQLGQDGAPLQVCVDGECHI 941

Query: 920  LGKVIVQ-----PDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDAR 974
            LG+V+       P     G++  ++ +  AL   L F  W + RKQ+             
Sbjct: 942  LGRVVRPGPDGVPQSTLLGILLPLLLLVAALATALVFSYWWR-RKQL------------- 987

Query: 975  VHTPHLDRLVSARSVSPTTEM-VSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSP 1033
            V  P+L+ L S    +  T + +     DYR+                    +       
Sbjct: 988  VLPPNLNDLASLDQTAGATPLPILYSGSDYRSGLALPAIDGLDSTTCVHGASF------- 1040

Query: 1034 ILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVY 1093
              +  + +   PLL+    I L  L+  L+  V+ V+I    ++ H + VIG+GHFG VY
Sbjct: 1041 --SDSEDESCVPLLRKE-SIQLRDLDSALLAEVKDVLIPHERVVTHSDRVIGKGHFGVVY 1097

Query: 1094 HGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSP 1153
            HG  +D    +I CA+KSL+RIT++ +V  FL EG++M+  +HPNVL+L+GI L  EG P
Sbjct: 1098 HGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLALIGIMLPPEGLP 1157

Query: 1154 LVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLD 1213
             V+LPYM HGDL  FIR+   NPTVKDLI FGLQVA+GM+YLA +KFVHRDLAARNCMLD
Sbjct: 1158 HVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQKFVHRDLAARNCMLD 1217

Query: 1214 EKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLL 1273
            E FTVKVADFGLARD+ D+EYYSV     A+LPVKWMALESLQT +FTTKSDVWSFGVLL
Sbjct: 1218 ESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYRFTTKSDVWSFGVLL 1277

Query: 1274 WELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 1333
            WEL+TRGAPPY  ++ FD+T +L QGRRL QPEYCPD LY+VM +CW     +RP+F  L
Sbjct: 1278 WELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPDSLYQVMQQCWEADPAVRPTFRVL 1337

Query: 1334 VSRISAIFSTFIGEHYVHVNATYVNV 1359
            V  +  I S  +G+HYV + ATY+N+
Sbjct: 1338 VGEVEQIVSALLGDHYVQLPATYMNL 1363


>gi|66932918 MER receptor tyrosine kinase precursor [Homo sapiens]
          Length = 999

 Score =  244 bits (622), Expect = 5e-64
 Identities = 139/339 (41%), Positives = 204/339 (60%), Gaps = 17/339 (5%)

Query: 1058 LNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITD 1117
            ++ EL   ++ VVI  + LI+   +++G G FG V  G L   DG  +  AVK++     
Sbjct: 569  VSEELQNKLEDVVIDRNLLIL--GKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNS 626

Query: 1118 IG-EVSQFLTEGIIMKDFSHPNVLSLLGICLR--SEG--SPLVVLPYMKHGDLRNFI--- 1169
               E+ +FL+E   MKDFSHPNV+ LLG+C+   S+G   P+V+LP+MK+GDL  ++   
Sbjct: 627  SQREIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYS 686

Query: 1170 RNET---HNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLA 1226
            R ET   H P ++ L+ F + +A GM+YL+++ F+HRDLAARNCML +  TV VADFGL+
Sbjct: 687  RLETGPKHIP-LQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLS 745

Query: 1227 RDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPD 1286
            + +Y  +YY       AK+PVKW+A+ESL  + +T+KSDVW+FGV +WE+ TRG  PYP 
Sbjct: 746  KKIYSGDYY--RQGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPG 803

Query: 1287 VNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIG 1346
            V   ++  YLL G RL QPE C D LYE+M  CW      RP+FS L  ++  +  + + 
Sbjct: 804  VQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLES-LP 862

Query: 1347 EHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPAS 1385
            +     +  YVN + +     L      A  +++  P S
Sbjct: 863  DVRNQADVIYVNTQLLESSEGLAQGSTLAPLDLNIDPDS 901


>gi|21536468 AXL receptor tyrosine kinase isoform 2 [Homo sapiens]
          Length = 885

 Score =  234 bits (597), Expect = 4e-61
 Identities = 126/288 (43%), Positives = 182/288 (63%), Gaps = 18/288 (6%)

Query: 1058 LNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLN-RIT 1116
            ++ EL + ++ V++      V   + +G G FG V  G L + D   +  AVK++   I 
Sbjct: 509  ISEELKEKLRDVMVDRHK--VALGKTLGEGEFGAVMEGQL-NQDDSILKVAVKTMKIAIC 565

Query: 1117 DIGEVSQFLTEGIIMKDFSHPNVLSLLGICLR-----SEGSPLVVLPYMKHGDLRNFIR- 1170
               E+  FL+E + MK+F HPNV+ L+G+C +     S  +P+V+LP+MKHGDL +F+  
Sbjct: 566  TRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLY 625

Query: 1171 -----NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGL 1225
                    + PT + L+ F   +A GM+YL++K+F+HRDLAARNCML+E  +V VADFGL
Sbjct: 626  SRLGDQPVYLPT-QMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGL 684

Query: 1226 ARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYP 1285
            ++ +Y+ +YY       AK+PVKW+A+ESL  + +T+KSDVWSFGV +WE+ TRG  PYP
Sbjct: 685  SKKIYNGDYY--RQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYP 742

Query: 1286 DVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 1333
             V   +I  YL QG RL QP  C D LY +M +CW    + RPSF+EL
Sbjct: 743  GVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTEL 790


>gi|21536466 AXL receptor tyrosine kinase isoform 1 [Homo sapiens]
          Length = 894

 Score =  234 bits (597), Expect = 4e-61
 Identities = 126/288 (43%), Positives = 182/288 (63%), Gaps = 18/288 (6%)

Query: 1058 LNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLN-RIT 1116
            ++ EL + ++ V++      V   + +G G FG V  G L + D   +  AVK++   I 
Sbjct: 518  ISEELKEKLRDVMVDRHK--VALGKTLGEGEFGAVMEGQL-NQDDSILKVAVKTMKIAIC 574

Query: 1117 DIGEVSQFLTEGIIMKDFSHPNVLSLLGICLR-----SEGSPLVVLPYMKHGDLRNFIR- 1170
               E+  FL+E + MK+F HPNV+ L+G+C +     S  +P+V+LP+MKHGDL +F+  
Sbjct: 575  TRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLY 634

Query: 1171 -----NETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGL 1225
                    + PT + L+ F   +A GM+YL++K+F+HRDLAARNCML+E  +V VADFGL
Sbjct: 635  SRLGDQPVYLPT-QMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGL 693

Query: 1226 ARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYP 1285
            ++ +Y+ +YY       AK+PVKW+A+ESL  + +T+KSDVWSFGV +WE+ TRG  PYP
Sbjct: 694  SKKIYNGDYY--RQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYP 751

Query: 1286 DVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 1333
             V   +I  YL QG RL QP  C D LY +M +CW    + RPSF+EL
Sbjct: 752  GVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTEL 799


>gi|27597078 TYRO3 protein tyrosine kinase [Homo sapiens]
          Length = 890

 Score =  232 bits (591), Expect = 2e-60
 Identities = 123/290 (42%), Positives = 173/290 (59%), Gaps = 15/290 (5%)

Query: 1053 IDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSL 1112
            +D   ++ EL + ++ V+I      +    ++G+G FG V    L   DG  +  AVK L
Sbjct: 495  LDSLGISDELKEKLEDVLIPEQQFTL--GRMLGKGEFGSVREAQLKQEDGSFVKVAVKML 552

Query: 1113 NR-ITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGS-----PLVVLPYMKHGDLR 1166
               I    ++ +FL E   MK+F HP+V  L+G+ LRS        P+V+LP+MKHGDL 
Sbjct: 553  KADIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLH 612

Query: 1167 NF-----IRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVA 1221
             F     I     N  ++ LI F + +A GM+YL+S+ F+HRDLAARNCML E  TV VA
Sbjct: 613  AFLLASRIGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVA 672

Query: 1222 DFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGA 1281
            DFGL+R +Y  +YY       +KLPVKW+ALESL    +T +SDVW+FGV +WE+MTRG 
Sbjct: 673  DFGLSRKIYSGDYY--RQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQ 730

Query: 1282 PPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFS 1331
             PY  +   +I  YL+ G RL QP  C + +Y++M +CW    + RPSF+
Sbjct: 731  TPYAGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFT 780


>gi|54607020 RYK receptor-like tyrosine kinase isoform 1 [Homo
            sapiens]
          Length = 610

 Score =  211 bits (538), Expect = 3e-54
 Identities = 127/365 (34%), Positives = 192/365 (52%), Gaps = 38/365 (10%)

Query: 980  LDRLVSARSVSPTTEMVSNESVDY-RATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSG 1038
            LD  +SA S S      S ++  Y RA  P +  P +S  G             P L   
Sbjct: 260  LDDSISASSSSQGLSQPSTQTTQYLRADTPNNATPITSSLGY------------PTLRIE 307

Query: 1039 DSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLL 1098
             +D+ S  L             E    V+ + I    + +   +V+  G FG ++HG L+
Sbjct: 308  KNDLRSVTLL------------EAKGKVKDIAISRERITL--KDVLQEGTFGRIFHGILI 353

Query: 1099 D--NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVV 1156
            D  +  K+    VK++       +V+  LTE   ++   H N+L +  +C+     P+V+
Sbjct: 354  DEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCKLRGLHHRNLLPITHVCIEEGEKPMVI 413

Query: 1157 LPYMKHGDLRNFIRN----ETHNPTV---KDLIGFGLQVAKGMKYLASKKFVHRDLAARN 1209
            LPYM  G+L+ F+R     E +NP     +DL+   +Q+A GM YLA ++ +H+DLAARN
Sbjct: 414  LPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARN 473

Query: 1210 CMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSF 1269
            C++D+   VK+ D  L+RD++  +Y+ + +      PV+WMALESL   +F++ SDVW+F
Sbjct: 474  CVIDDTLQVKITDNALSRDLFPMDYHCLGDNENR--PVRWMALESLVNNEFSSASDVWAF 531

Query: 1270 GVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPS 1329
            GV LWELMT G  PY D++ F++  YL  G R+ QP  CPD L+ VM  CW    E RP 
Sbjct: 532  GVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPK 591

Query: 1330 FSELV 1334
            F +LV
Sbjct: 592  FQQLV 596


>gi|54607018 RYK receptor-like tyrosine kinase isoform 2 [Homo
            sapiens]
          Length = 607

 Score =  211 bits (537), Expect = 4e-54
 Identities = 117/331 (35%), Positives = 186/331 (56%), Gaps = 14/331 (4%)

Query: 1016 SQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQN-TVHIDLSALNPELVQAVQHVV--IG 1072
            S + S + +  P T  +  L +   + ++P+    T+ I+ + L    +   +  V  I 
Sbjct: 265  SASSSSQGLSQPSTQTTQYLRADTPNNATPITSYPTLRIEKNDLRSVTLLEAKGKVKDIA 324

Query: 1073 PSSLIVHFNEVIGRGHFGCVYHGTLLD--NDGKKIHCAVKSLNRITDIGEVSQFLTEGII 1130
             S   +   +V+  G FG ++HG L+D  +  K+    VK++       +V+  LTE   
Sbjct: 325  ISRERITLKDVLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMMLTESCK 384

Query: 1131 MKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRN----ETHNPTV---KDLIG 1183
            ++   H N+L +  +C+     P+V+LPYM  G+L+ F+R     E +NP     +DL+ 
Sbjct: 385  LRGLHHRNLLPITHVCIEEGEKPMVILPYMNWGNLKLFLRQCKLVEANNPQAISQQDLVH 444

Query: 1184 FGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243
              +Q+A GM YLA ++ +H+DLAARNC++D+   VK+ D  L+RD++  +Y+ + +    
Sbjct: 445  MAIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGDNENR 504

Query: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303
              PV+WMALESL   +F++ SDVW+FGV LWELMT G  PY D++ F++  YL  G R+ 
Sbjct: 505  --PVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYRIA 562

Query: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELV 1334
            QP  CPD L+ VM  CW    E RP F +LV
Sbjct: 563  QPINCPDELFAVMACCWALDPEERPKFQQLV 593


>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
            sapiens]
          Length = 1367

 Score =  211 bits (536), Expect = 5e-54
 Identities = 117/297 (39%), Positives = 177/297 (59%), Gaps = 19/297 (6%)

Query: 1056 SALNPELVQAVQHVVIGPSSLI---VHFNEVIGRGHFGCVYHGTL--LDNDGKKIHCAVK 1110
            +++NPE   A    V     +    +  +  +G+G FG VY G    +  D  +   A+K
Sbjct: 974  ASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIK 1033

Query: 1111 SLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSP-LVVLPYMKHGDLRNFI 1169
            ++N    + E  +FL E  +MK+F+  +V+ LLG+   S+G P LV++  M  GDL++++
Sbjct: 1034 TVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVV--SQGQPTLVIMELMTRGDLKSYL 1091

Query: 1170 RN---ETHN------PTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKV 1220
            R+   E  N      P++  +I    ++A GM YL + KFVHRDLAARNCM+ E FTVK+
Sbjct: 1092 RSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKI 1151

Query: 1221 ADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRG 1280
             DFG+ RD+Y+ +YY    K    LPV+WM+ ESL+   FTT SDVWSFGV+LWE+ T  
Sbjct: 1152 GDFGMTRDIYETDYYRKGGK--GLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLA 1209

Query: 1281 APPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRI 1337
              PY  ++   +  ++++G  L +P+ CPD L+E+M  CW    +MRPSF E++S I
Sbjct: 1210 EQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSI 1266


>gi|119395738 insulin receptor isoform Short precursor [Homo sapiens]
          Length = 1370

 Score =  208 bits (529), Expect = 3e-53
 Identities = 111/264 (42%), Positives = 164/264 (62%), Gaps = 16/264 (6%)

Query: 1084 IGRGHFGCVYHGTLLD--NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS 1141
            +G+G FG VY G   D      +   AVK++N    + E  +FL E  +MK F+  +V+ 
Sbjct: 1017 LGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVR 1076

Query: 1142 LLGICLRSEGSP-LVVLPYMKHGDLRNFIRN---ETHN------PTVKDLIGFGLQVAKG 1191
            LLG+   S+G P LVV+  M HGDL++++R+   E  N      PT++++I    ++A G
Sbjct: 1077 LLGVV--SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADG 1134

Query: 1192 MKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMA 1251
            M YL +KKFVHRDLAARNCM+   FTVK+ DFG+ RD+Y+ +YY    K    LPV+WMA
Sbjct: 1135 MAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGK--GLLPVRWMA 1192

Query: 1252 LESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDP 1311
             ESL+   FTT SD+WSFGV+LWE+ +    PY  ++   +  +++ G  L QP+ CP+ 
Sbjct: 1193 PESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPER 1252

Query: 1312 LYEVMLKCWHPKAEMRPSFSELVS 1335
            + ++M  CW    +MRP+F E+V+
Sbjct: 1253 VTDLMRMCWQFNPKMRPTFLEIVN 1276


>gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]
          Length = 1382

 Score =  208 bits (529), Expect = 3e-53
 Identities = 111/264 (42%), Positives = 164/264 (62%), Gaps = 16/264 (6%)

Query: 1084 IGRGHFGCVYHGTLLD--NDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS 1141
            +G+G FG VY G   D      +   AVK++N    + E  +FL E  +MK F+  +V+ 
Sbjct: 1029 LGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVR 1088

Query: 1142 LLGICLRSEGSP-LVVLPYMKHGDLRNFIRN---ETHN------PTVKDLIGFGLQVAKG 1191
            LLG+   S+G P LVV+  M HGDL++++R+   E  N      PT++++I    ++A G
Sbjct: 1089 LLGVV--SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADG 1146

Query: 1192 MKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMA 1251
            M YL +KKFVHRDLAARNCM+   FTVK+ DFG+ RD+Y+ +YY    K    LPV+WMA
Sbjct: 1147 MAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGK--GLLPVRWMA 1204

Query: 1252 LESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDP 1311
             ESL+   FTT SD+WSFGV+LWE+ +    PY  ++   +  +++ G  L QP+ CP+ 
Sbjct: 1205 PESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPER 1264

Query: 1312 LYEVMLKCWHPKAEMRPSFSELVS 1335
            + ++M  CW    +MRP+F E+V+
Sbjct: 1265 VTDLMRMCWQFNPKMRPTFLEIVN 1288


>gi|19924165 proto-oncogene c-ros-1 protein precursor [Homo sapiens]
          Length = 2347

 Score =  204 bits (518), Expect = 6e-52
 Identities = 113/281 (40%), Positives = 165/281 (58%), Gaps = 17/281 (6%)

Query: 1083 VIGRGHFGCVYHGTLLDNDGK---KIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNV 1139
            ++G G FG VY GT +D  G    +I  AVK+L + +   E  +FL E  +M  F+HPN+
Sbjct: 1950 LLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNI 2009

Query: 1140 LSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNET----HNP--TVKDLIGFGLQVAKGMK 1193
            L  LG+CL +E    ++L  M+ GDL  ++R       + P  T+ DL+   + ++KG  
Sbjct: 2010 LKQLGVCLLNEPQ-YIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 2068

Query: 1194 YLASKKFVHRDLAARNCMLDEK-FT----VKVADFGLARDMYDKEYYSVHNKTGAKLPVK 1248
            YL    F+HRDLAARNC++  K +T    VK+ DFGLARD+Y  +YY    +    LPV+
Sbjct: 2069 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGE--GLLPVR 2126

Query: 1249 WMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYC 1308
            WMA ESL    FTT+SDVWSFG+L+WE++T G  PYP  +  D+  Y+  G RL  P  C
Sbjct: 2127 WMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNC 2186

Query: 1309 PDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHY 1349
            PD L+ +M +CW  + + RP+F  +  ++    + F+   Y
Sbjct: 2187 PDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLFRNFFLNSIY 2227


>gi|31657140 insulin receptor-related receptor precursor [Homo
            sapiens]
          Length = 1297

 Score =  201 bits (512), Expect = 3e-51
 Identities = 110/266 (41%), Positives = 161/266 (60%), Gaps = 16/266 (6%)

Query: 1084 IGRGHFGCVYHGTL--LDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS 1141
            +G+G FG VY G    L+   +    A+K++N +    E  +FL E  +MK F   +V+ 
Sbjct: 985  LGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHVVR 1044

Query: 1142 LLGICLRSEGSP-LVVLPYMKHGDLRNFIRN---ETHN------PTVKDLIGFGLQVAKG 1191
            LLG+   S+G P LV++  M  GDL++ +R+   E  N      P + ++I    ++A G
Sbjct: 1045 LLGVV--SQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALGEMIQMAGEIADG 1102

Query: 1192 MKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMA 1251
            M YLA+ KFVHRDLAARNCM+ + FTVK+ DFG+ RD+Y+ +YY    K    LPV+WMA
Sbjct: 1103 MAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGK--GLLPVRWMA 1160

Query: 1252 LESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDP 1311
             ESL+   FTT SDVWSFGV+LWE++T    PY  ++   +  +++ G  L + E CP  
Sbjct: 1161 PESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQ 1220

Query: 1312 LYEVMLKCWHPKAEMRPSFSELVSRI 1337
            L E+M +CW P   +RPSF+ ++  I
Sbjct: 1221 LQELMSRCWQPNPRLRPSFTHILDSI 1246


>gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homolog 4
            isoform JM-a/CVT-2 precursor [Homo sapiens]
          Length = 1292

 Score =  199 bits (505), Expect = 2e-50
 Identities = 112/262 (42%), Positives = 154/262 (58%), Gaps = 13/262 (4%)

Query: 1082 EVIGRGHFGCVYHGTLL-DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1140
            +V+G G FG VY G  + + +  KI  A+K LN  T      +F+ E +IM    HP+++
Sbjct: 722  KVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLV 781

Query: 1141 SLLGICLRSEGSPLV--VLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
             LLG+CL    SP +  V   M HG L  ++     N   + L+ + +Q+AKGM YL  +
Sbjct: 782  RLLGVCL----SPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEER 837

Query: 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMY--DKEYYSVHNKTGAKLPVKWMALESLQ 1256
            + VHRDLAARN ++     VK+ DFGLAR +   +KEY    N  G K+P+KWMALE + 
Sbjct: 838  RLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEY----NADGGKMPIKWMALECIH 893

Query: 1257 TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVM 1316
             +KFT +SDVWS+GV +WELMT G  PY  + T +I   L +G RL QP  C   +Y VM
Sbjct: 894  YRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVM 953

Query: 1317 LKCWHPKAEMRPSFSELVSRIS 1338
            +KCW   A+ RP F EL +  S
Sbjct: 954  VKCWMIDADSRPKFKELAAEFS 975


>gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolog 4
            isoform JM-a/CVT-1 precursor [Homo sapiens]
          Length = 1308

 Score =  199 bits (505), Expect = 2e-50
 Identities = 112/262 (42%), Positives = 154/262 (58%), Gaps = 13/262 (4%)

Query: 1082 EVIGRGHFGCVYHGTLL-DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL 1140
            +V+G G FG VY G  + + +  KI  A+K LN  T      +F+ E +IM    HP+++
Sbjct: 722  KVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLV 781

Query: 1141 SLLGICLRSEGSPLV--VLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASK 1198
             LLG+CL    SP +  V   M HG L  ++     N   + L+ + +Q+AKGM YL  +
Sbjct: 782  RLLGVCL----SPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEER 837

Query: 1199 KFVHRDLAARNCMLDEKFTVKVADFGLARDMY--DKEYYSVHNKTGAKLPVKWMALESLQ 1256
            + VHRDLAARN ++     VK+ DFGLAR +   +KEY    N  G K+P+KWMALE + 
Sbjct: 838  RLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEY----NADGGKMPIKWMALECIH 893

Query: 1257 TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVM 1316
             +KFT +SDVWS+GV +WELMT G  PY  + T +I   L +G RL QP  C   +Y VM
Sbjct: 894  YRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVM 953

Query: 1317 LKCWHPKAEMRPSFSELVSRIS 1338
            +KCW   A+ RP F EL +  S
Sbjct: 954  VKCWMIDADSRPKFKELAAEFS 975


>gi|254028242 fibroblast growth factor receptor 3 isoform 3 precursor
            [Homo sapiens]
          Length = 808

 Score =  198 bits (504), Expect = 3e-50
 Identities = 133/388 (34%), Positives = 205/388 (52%), Gaps = 41/388 (10%)

Query: 990  SPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQN 1049
            SP  + + + +V   + FP  +  +   N S      PL  ++  L+SG+     P L N
Sbjct: 402  SPPKKGLGSPTVHKISRFPLKRQVSLESNASMSS-NTPLVRIAR-LSSGEG----PTLAN 455

Query: 1050 TVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLL----DNDGKKI 1105
               ++L A +P+   +   + +G         + +G G FG V     +    D   K +
Sbjct: 456  VSELELPA-DPKWELSRARLTLG---------KPLGEGCFGQVVMAEAIGIDKDRAAKPV 505

Query: 1106 HCAVKSLNRITDIGEVSQFLTEGIIMKDFS-HPNVLSLLGICLRSEGSPLVVL-PYMKHG 1163
              AVK L       ++S  ++E  +MK    H N+++LLG C  ++G PL VL  Y   G
Sbjct: 506  TVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGAC--TQGGPLYVLVEYAAKG 563

Query: 1164 DLRNFIRN----------ETHNP-----TVKDLIGFGLQVAKGMKYLASKKFVHRDLAAR 1208
            +LR F+R           +T  P     T KDL+    QVA+GM+YLAS+K +HRDLAAR
Sbjct: 564  NLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAAR 623

Query: 1209 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1268
            N ++ E   +K+ADFGLARD+++ +YY     T  +LPVKWMA E+L  + +T +SDVWS
Sbjct: 624  NVLVTEDNVMKIADFGLARDVHNLDYYK--KTTNGRLPVKWMAPEALFDRVYTHQSDVWS 681

Query: 1269 FGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRP 1328
            FGVLLWE+ T G  PYP +   ++   L +G R+ +P  C   LY +M +CWH     RP
Sbjct: 682  FGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRP 741

Query: 1329 SFSELVSRISAIFSTFIGEHYVHVNATY 1356
            +F +LV  +  + +    + Y+ ++A +
Sbjct: 742  TFKQLVEDLDRVLTVTSTDEYLDLSAPF 769


>gi|4503711 fibroblast growth factor receptor 3 isoform 1 precursor
            [Homo sapiens]
          Length = 806

 Score =  198 bits (504), Expect = 3e-50
 Identities = 133/388 (34%), Positives = 205/388 (52%), Gaps = 41/388 (10%)

Query: 990  SPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQN 1049
            SP  + + + +V   + FP  +  +   N S      PL  ++  L+SG+     P L N
Sbjct: 400  SPPKKGLGSPTVHKISRFPLKRQVSLESNASMSS-NTPLVRIAR-LSSGEG----PTLAN 453

Query: 1050 TVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLL----DNDGKKI 1105
               ++L A +P+   +   + +G         + +G G FG V     +    D   K +
Sbjct: 454  VSELELPA-DPKWELSRARLTLG---------KPLGEGCFGQVVMAEAIGIDKDRAAKPV 503

Query: 1106 HCAVKSLNRITDIGEVSQFLTEGIIMKDFS-HPNVLSLLGICLRSEGSPLVVL-PYMKHG 1163
              AVK L       ++S  ++E  +MK    H N+++LLG C  ++G PL VL  Y   G
Sbjct: 504  TVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGAC--TQGGPLYVLVEYAAKG 561

Query: 1164 DLRNFIRN----------ETHNP-----TVKDLIGFGLQVAKGMKYLASKKFVHRDLAAR 1208
            +LR F+R           +T  P     T KDL+    QVA+GM+YLAS+K +HRDLAAR
Sbjct: 562  NLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAAR 621

Query: 1209 NCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWS 1268
            N ++ E   +K+ADFGLARD+++ +YY     T  +LPVKWMA E+L  + +T +SDVWS
Sbjct: 622  NVLVTEDNVMKIADFGLARDVHNLDYYK--KTTNGRLPVKWMAPEALFDRVYTHQSDVWS 679

Query: 1269 FGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRP 1328
            FGVLLWE+ T G  PYP +   ++   L +G R+ +P  C   LY +M +CWH     RP
Sbjct: 680  FGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRP 739

Query: 1329 SFSELVSRISAIFSTFIGEHYVHVNATY 1356
            +F +LV  +  + +    + Y+ ++A +
Sbjct: 740  TFKQLVEDLDRVLTVTSTDEYLDLSAPF 767


>gi|13112048 fibroblast growth factor receptor 3 isoform 2 precursor
            [Homo sapiens]
          Length = 694

 Score =  197 bits (502), Expect = 4e-50
 Identities = 124/343 (36%), Positives = 187/343 (54%), Gaps = 39/343 (11%)

Query: 1035 LTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYH 1094
            L+SG+     P L N   ++L A +P+   +   + +G         + +G G FG V  
Sbjct: 331  LSSGEG----PTLANVSELELPA-DPKWELSRARLTLG---------KPLGEGCFGQVVM 376

Query: 1095 GTLL----DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFS-HPNVLSLLGICLRS 1149
               +    D   K +  AVK L       ++S  ++E  +MK    H N+++LLG C  +
Sbjct: 377  AEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGAC--T 434

Query: 1150 EGSPLVVL-PYMKHGDLRNFIRN----------ETHNP-----TVKDLIGFGLQVAKGMK 1193
            +G PL VL  Y   G+LR F+R           +T  P     T KDL+    QVA+GM+
Sbjct: 435  QGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGME 494

Query: 1194 YLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALE 1253
            YLAS+K +HRDLAARN ++ E   +K+ADFGLARD+++ +YY     T  +LPVKWMA E
Sbjct: 495  YLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYK--KTTNGRLPVKWMAPE 552

Query: 1254 SLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLY 1313
            +L  + +T +SDVWSFGVLLWE+ T G  PYP +   ++   L +G R+ +P  C   LY
Sbjct: 553  ALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLY 612

Query: 1314 EVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATY 1356
             +M +CWH     RP+F +LV  +  + +    + Y+ ++A +
Sbjct: 613  MIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPF 655


>gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]
          Length = 822

 Score =  195 bits (495), Expect = 3e-49
 Identities = 98/264 (37%), Positives = 157/264 (59%), Gaps = 10/264 (3%)

Query: 1078 VHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
            V   E++G+G+FG VY GTL D     +    + L +   I    +FL E  I+K + HP
Sbjct: 563  VILGELLGKGNFGEVYKGTLKDKTSVAVKTCKEDLPQELKI----KFLQEAKILKQYDHP 618

Query: 1138 NVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLAS 1197
            N++ L+G+C + +    +++  +  GD   F+R +     +K L+ F L  A GM YL S
Sbjct: 619  NIVKLIGVCTQRQ-PVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLES 677

Query: 1198 KKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAK-LPVKWMALESLQ 1256
            K  +HRDLAARNC++ E   +K++DFG++R    +E   V++ +G K +P+KW A E+L 
Sbjct: 678  KNCIHRDLAARNCLVGENNVLKISDFGMSR----QEDGGVYSSSGLKQIPIKWTAPEALN 733

Query: 1257 TQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVM 1316
              +++++SDVWSFG+LLWE  + G  PYP +        + +G R+  P++CP+ + ++M
Sbjct: 734  YGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISKIM 793

Query: 1317 LKCWHPKAEMRPSFSELVSRISAI 1340
            +KCW  K E RP FSEL   ++ I
Sbjct: 794  MKCWDYKPENRPKFSELQKELTII 817


>gi|13186236 fibroblast growth factor receptor 1 isoform 4 precursor
            [Homo sapiens]
          Length = 731

 Score =  194 bits (493), Expect = 5e-49
 Identities = 111/290 (38%), Positives = 164/290 (56%), Gaps = 23/290 (7%)

Query: 1084 IGRGHFGCVYHGTLL----DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFS-HPN 1138
            +G G FG V     +    D   +    AVK L       ++S  ++E  +MK    H N
Sbjct: 393  LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 452

Query: 1139 VLSLLGICLRSEGSPLVVLPYMKHGDLRNFIR-----------NETHNP----TVKDLIG 1183
            +++LLG C + +G   V++ Y   G+LR +++           N +HNP    + KDL+ 
Sbjct: 453  IINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVS 511

Query: 1184 FGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243
               QVA+GM+YLASKK +HRDLAARN ++ E   +K+ADFGLARD++  +YY     T  
Sbjct: 512  CAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYK--KTTNG 569

Query: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303
            +LPVKWMA E+L  + +T +SDVWSFGVLLWE+ T G  PYP V   ++   L +G R+ 
Sbjct: 570  RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMD 629

Query: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVN 1353
            +P  C + LY +M  CWH     RP+F +LV  +  I +    + Y+ ++
Sbjct: 630  KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS 679


>gi|13186234 fibroblast growth factor receptor 1 isoform 3 precursor
            [Homo sapiens]
          Length = 733

 Score =  194 bits (493), Expect = 5e-49
 Identities = 111/290 (38%), Positives = 164/290 (56%), Gaps = 23/290 (7%)

Query: 1084 IGRGHFGCVYHGTLL----DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFS-HPN 1138
            +G G FG V     +    D   +    AVK L       ++S  ++E  +MK    H N
Sbjct: 395  LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 454

Query: 1139 VLSLLGICLRSEGSPLVVLPYMKHGDLRNFIR-----------NETHNP----TVKDLIG 1183
            +++LLG C + +G   V++ Y   G+LR +++           N +HNP    + KDL+ 
Sbjct: 455  IINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVS 513

Query: 1184 FGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243
               QVA+GM+YLASKK +HRDLAARN ++ E   +K+ADFGLARD++  +YY     T  
Sbjct: 514  CAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYK--KTTNG 571

Query: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303
            +LPVKWMA E+L  + +T +SDVWSFGVLLWE+ T G  PYP V   ++   L +G R+ 
Sbjct: 572  RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMD 631

Query: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVN 1353
            +P  C + LY +M  CWH     RP+F +LV  +  I +    + Y+ ++
Sbjct: 632  KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS 681


>gi|13186251 fibroblast growth factor receptor 1 isoform 2 precursor
            [Homo sapiens]
          Length = 820

 Score =  194 bits (493), Expect = 5e-49
 Identities = 111/290 (38%), Positives = 164/290 (56%), Gaps = 23/290 (7%)

Query: 1084 IGRGHFGCVYHGTLL----DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFS-HPN 1138
            +G G FG V     +    D   +    AVK L       ++S  ++E  +MK    H N
Sbjct: 482  LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 541

Query: 1139 VLSLLGICLRSEGSPLVVLPYMKHGDLRNFIR-----------NETHNP----TVKDLIG 1183
            +++LLG C + +G   V++ Y   G+LR +++           N +HNP    + KDL+ 
Sbjct: 542  IINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVS 600

Query: 1184 FGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243
               QVA+GM+YLASKK +HRDLAARN ++ E   +K+ADFGLARD++  +YY     T  
Sbjct: 601  CAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYK--KTTNG 658

Query: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303
            +LPVKWMA E+L  + +T +SDVWSFGVLLWE+ T G  PYP V   ++   L +G R+ 
Sbjct: 659  RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMD 718

Query: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVN 1353
            +P  C + LY +M  CWH     RP+F +LV  +  I +    + Y+ ++
Sbjct: 719  KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS 768


>gi|105990522 fibroblast growth factor receptor 1 isoform 1 precursor
            [Homo sapiens]
          Length = 822

 Score =  194 bits (493), Expect = 5e-49
 Identities = 111/290 (38%), Positives = 164/290 (56%), Gaps = 23/290 (7%)

Query: 1084 IGRGHFGCVYHGTLL----DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFS-HPN 1138
            +G G FG V     +    D   +    AVK L       ++S  ++E  +MK    H N
Sbjct: 484  LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 543

Query: 1139 VLSLLGICLRSEGSPLVVLPYMKHGDLRNFIR-----------NETHNP----TVKDLIG 1183
            +++LLG C + +G   V++ Y   G+LR +++           N +HNP    + KDL+ 
Sbjct: 544  IINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVS 602

Query: 1184 FGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243
               QVA+GM+YLASKK +HRDLAARN ++ E   +K+ADFGLARD++  +YY     T  
Sbjct: 603  CAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYK--KTTNG 660

Query: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303
            +LPVKWMA E+L  + +T +SDVWSFGVLLWE+ T G  PYP V   ++   L +G R+ 
Sbjct: 661  RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMD 720

Query: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVN 1353
            +P  C + LY +M  CWH     RP+F +LV  +  I +    + Y+ ++
Sbjct: 721  KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS 770


>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
            [Homo sapiens]
          Length = 1130

 Score =  193 bits (491), Expect = 8e-49
 Identities = 108/261 (41%), Positives = 153/261 (58%), Gaps = 14/261 (5%)

Query: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143
            +G G +G VY G         +  AVK+L    D  EV +FL E  +MK+  HPN++ LL
Sbjct: 248  LGGGQYGEVYEGVWKKYS---LTVAVKTLKE--DTMEVEEFLKEAAVMKEIKHPNLVQLL 302

Query: 1144 GICLRSEGSPLVVLPYMKHGDLRNFIRN---ETHNPTVKDLIGFGLQVAKGMKYLASKKF 1200
            G+C R E    ++  +M +G+L +++R    +  N  V  L+    Q++  M+YL  K F
Sbjct: 303  GVCTR-EPPFYIITEFMTYGNLLDYLRECNRQEVNAVV--LLYMATQISSAMEYLEKKNF 359

Query: 1201 VHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF 1260
            +HRDLAARNC++ E   VKVADFGL+R M   + Y+ H   GAK P+KW A ESL   KF
Sbjct: 360  IHRDLAARNCLVGENHLVKVADFGLSRLMTG-DTYTAH--AGAKFPIKWTAPESLAYNKF 416

Query: 1261 TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW 1320
            + KSDVW+FGVLLWE+ T G  PYP ++   +   L +  R+ +PE CP+ +YE+M  CW
Sbjct: 417  SIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACW 476

Query: 1321 HPKAEMRPSFSELVSRISAIF 1341
                  RPSF+E+      +F
Sbjct: 477  QWNPSDRPSFAEIHQAFETMF 497


>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
            [Homo sapiens]
          Length = 1149

 Score =  193 bits (491), Expect = 8e-49
 Identities = 108/261 (41%), Positives = 153/261 (58%), Gaps = 14/261 (5%)

Query: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143
            +G G +G VY G         +  AVK+L    D  EV +FL E  +MK+  HPN++ LL
Sbjct: 267  LGGGQYGEVYEGVWKKYS---LTVAVKTLKE--DTMEVEEFLKEAAVMKEIKHPNLVQLL 321

Query: 1144 GICLRSEGSPLVVLPYMKHGDLRNFIRN---ETHNPTVKDLIGFGLQVAKGMKYLASKKF 1200
            G+C R E    ++  +M +G+L +++R    +  N  V  L+    Q++  M+YL  K F
Sbjct: 322  GVCTR-EPPFYIITEFMTYGNLLDYLRECNRQEVNAVV--LLYMATQISSAMEYLEKKNF 378

Query: 1201 VHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF 1260
            +HRDLAARNC++ E   VKVADFGL+R M   + Y+ H   GAK P+KW A ESL   KF
Sbjct: 379  IHRDLAARNCLVGENHLVKVADFGLSRLMTG-DTYTAH--AGAKFPIKWTAPESLAYNKF 435

Query: 1261 TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW 1320
            + KSDVW+FGVLLWE+ T G  PYP ++   +   L +  R+ +PE CP+ +YE+M  CW
Sbjct: 436  SIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACW 495

Query: 1321 HPKAEMRPSFSELVSRISAIF 1341
                  RPSF+E+      +F
Sbjct: 496  QWNPSDRPSFAEIHQAFETMF 516


>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
          Length = 1167

 Score =  193 bits (491), Expect = 8e-49
 Identities = 114/284 (40%), Positives = 155/284 (54%), Gaps = 11/284 (3%)

Query: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143
            +G G +G VY G         +  AVK+L    D  EV +FL E  +MK+  HPN++ LL
Sbjct: 279  LGGGQYGEVYVGVWKKYS---LTVAVKTLKE--DTMEVEEFLKEAAVMKEIKHPNLVQLL 333

Query: 1144 GICLRSEGSPLVVLPYMKHGDLRNFIRN-ETHNPTVKDLIGFGLQVAKGMKYLASKKFVH 1202
            G+C   E    +V  YM +G+L +++R       T   L+    Q++  M+YL  K F+H
Sbjct: 334  GVCTL-EPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 392

Query: 1203 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT 1262
            RDLAARNC++ E   VKVADFGL+R M   + Y+ H   GAK P+KW A ESL    F+ 
Sbjct: 393  RDLAARNCLVGENHVVKVADFGLSRLMTG-DTYTAH--AGAKFPIKWTAPESLAYNTFSI 449

Query: 1263 KSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP 1322
            KSDVW+FGVLLWE+ T G  PYP ++   +   L +G R+ QPE CP  +YE+M  CW  
Sbjct: 450  KSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKW 509

Query: 1323 KAEMRPSFSELVSRISAIF-STFIGEHYVHVNATYVNVKCVAPY 1365
                RPSF+E       +F  + I E          +   V PY
Sbjct: 510  SPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPY 553


>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
          Length = 1182

 Score =  193 bits (491), Expect = 8e-49
 Identities = 114/284 (40%), Positives = 155/284 (54%), Gaps = 11/284 (3%)

Query: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143
            +G G +G VY G         +  AVK+L    D  EV +FL E  +MK+  HPN++ LL
Sbjct: 294  LGGGQYGEVYVGVWKKYS---LTVAVKTLKE--DTMEVEEFLKEAAVMKEIKHPNLVQLL 348

Query: 1144 GICLRSEGSPLVVLPYMKHGDLRNFIRN-ETHNPTVKDLIGFGLQVAKGMKYLASKKFVH 1202
            G+C   E    +V  YM +G+L +++R       T   L+    Q++  M+YL  K F+H
Sbjct: 349  GVCTL-EPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 407

Query: 1203 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT 1262
            RDLAARNC++ E   VKVADFGL+R M   + Y+ H   GAK P+KW A ESL    F+ 
Sbjct: 408  RDLAARNCLVGENHVVKVADFGLSRLMTG-DTYTAH--AGAKFPIKWTAPESLAYNTFSI 464

Query: 1263 KSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP 1322
            KSDVW+FGVLLWE+ T G  PYP ++   +   L +G R+ QPE CP  +YE+M  CW  
Sbjct: 465  KSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKW 524

Query: 1323 KAEMRPSFSELVSRISAIF-STFIGEHYVHVNATYVNVKCVAPY 1365
                RPSF+E       +F  + I E          +   V PY
Sbjct: 525  SPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPY 568


>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
          Length = 1064

 Score =  193 bits (491), Expect = 8e-49
 Identities = 114/284 (40%), Positives = 155/284 (54%), Gaps = 11/284 (3%)

Query: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143
            +G G +G VY G         +  AVK+L    D  EV +FL E  +MK+  HPN++ LL
Sbjct: 279  LGGGQYGEVYVGVWKKYS---LTVAVKTLKE--DTMEVEEFLKEAAVMKEIKHPNLVQLL 333

Query: 1144 GICLRSEGSPLVVLPYMKHGDLRNFIRN-ETHNPTVKDLIGFGLQVAKGMKYLASKKFVH 1202
            G+C   E    +V  YM +G+L +++R       T   L+    Q++  M+YL  K F+H
Sbjct: 334  GVCTL-EPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 392

Query: 1203 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT 1262
            RDLAARNC++ E   VKVADFGL+R M   + Y+ H   GAK P+KW A ESL    F+ 
Sbjct: 393  RDLAARNCLVGENHVVKVADFGLSRLMTG-DTYTAH--AGAKFPIKWTAPESLAYNTFSI 449

Query: 1263 KSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP 1322
            KSDVW+FGVLLWE+ T G  PYP ++   +   L +G R+ QPE CP  +YE+M  CW  
Sbjct: 450  KSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKW 509

Query: 1323 KAEMRPSFSELVSRISAIF-STFIGEHYVHVNATYVNVKCVAPY 1365
                RPSF+E       +F  + I E          +   V PY
Sbjct: 510  SPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPY 553


>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
          Length = 1146

 Score =  193 bits (491), Expect = 8e-49
 Identities = 114/284 (40%), Positives = 155/284 (54%), Gaps = 11/284 (3%)

Query: 1084 IGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLL 1143
            +G G +G VY G         +  AVK+L    D  EV +FL E  +MK+  HPN++ LL
Sbjct: 258  LGGGQYGEVYVGVWKKYS---LTVAVKTLKE--DTMEVEEFLKEAAVMKEIKHPNLVQLL 312

Query: 1144 GICLRSEGSPLVVLPYMKHGDLRNFIRN-ETHNPTVKDLIGFGLQVAKGMKYLASKKFVH 1202
            G+C   E    +V  YM +G+L +++R       T   L+    Q++  M+YL  K F+H
Sbjct: 313  GVCTL-EPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 371

Query: 1203 RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT 1262
            RDLAARNC++ E   VKVADFGL+R M   + Y+ H   GAK P+KW A ESL    F+ 
Sbjct: 372  RDLAARNCLVGENHVVKVADFGLSRLMTG-DTYTAH--AGAKFPIKWTAPESLAYNTFSI 428

Query: 1263 KSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP 1322
            KSDVW+FGVLLWE+ T G  PYP ++   +   L +G R+ QPE CP  +YE+M  CW  
Sbjct: 429  KSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKW 488

Query: 1323 KAEMRPSFSELVSRISAIF-STFIGEHYVHVNATYVNVKCVAPY 1365
                RPSF+E       +F  + I E          +   V PY
Sbjct: 489  SPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPY 532


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,871,629
Number of Sequences: 37866
Number of extensions: 2367398
Number of successful extensions: 7037
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 519
Number of HSP's successfully gapped in prelim test: 240
Number of HSP's that attempted gapping in prelim test: 5085
Number of HSP's gapped (non-prelim): 1045
length of query: 1390
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1275
effective length of database: 13,892,928
effective search space: 17713483200
effective search space used: 17713483200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.