BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|126352440 elastin isoform a precursor [Homo sapiens] (724 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|126352440 elastin isoform a precursor [Homo sapiens] 1447 0.0 gi|126352608 elastin isoform e precursor [Homo sapiens] 1401 0.0 gi|126352446 elastin isoform d precursor [Homo sapiens] 1393 0.0 gi|126352322 elastin isoform c precursor [Homo sapiens] 1347 0.0 gi|126352700 elastin isoform b precursor [Homo sapiens] 1325 0.0 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 191 3e-48 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 182 7e-46 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 182 7e-46 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 182 9e-46 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 181 2e-45 gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ... 168 2e-41 gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s... 168 2e-41 gi|48762934 alpha 2 type I collagen [Homo sapiens] 167 3e-41 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 167 4e-41 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 167 4e-41 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 167 4e-41 gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] 160 5e-39 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 156 6e-38 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 150 3e-36 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 149 1e-35 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 146 8e-35 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 146 8e-35 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 146 8e-35 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 145 1e-34 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 145 1e-34 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 145 1e-34 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 145 2e-34 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 143 6e-34 gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 142 8e-34 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 142 1e-33 >gi|126352440 elastin isoform a precursor [Homo sapiens] Length = 724 Score = 1447 bits (3745), Expect = 0.0 Identities = 724/724 (100%), Positives = 724/724 (100%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP Sbjct: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 Query: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG Sbjct: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 Query: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT Sbjct: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 Query: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP Sbjct: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 Query: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV Sbjct: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 Query: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA 480 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA Sbjct: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA 480 Query: 481 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 540 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL Sbjct: 481 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 540 Query: 541 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 600 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP Sbjct: 541 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 600 Query: 601 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 660 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV Sbjct: 601 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 660 Query: 661 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG 720 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG Sbjct: 661 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG 720 Query: 721 RKRK 724 RKRK Sbjct: 721 RKRK 724 >gi|126352608 elastin isoform e precursor [Homo sapiens] Length = 705 Score = 1401 bits (3626), Expect = 0.0 Identities = 705/724 (97%), Positives = 705/724 (97%), Gaps = 19/724 (2%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP Sbjct: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 Query: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG Sbjct: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 Query: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT Sbjct: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 Query: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP Sbjct: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 Query: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV Sbjct: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 Query: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA 480 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVPGVGVA Sbjct: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVPGVGVA 461 Query: 481 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 540 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL Sbjct: 462 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 521 Query: 541 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 600 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP Sbjct: 522 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 581 Query: 601 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 660 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV Sbjct: 582 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 641 Query: 661 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG 720 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG Sbjct: 642 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG 701 Query: 721 RKRK 724 RKRK Sbjct: 702 RKRK 705 >gi|126352446 elastin isoform d precursor [Homo sapiens] Length = 711 Score = 1393 bits (3606), Expect = 0.0 Identities = 706/729 (96%), Positives = 706/729 (96%), Gaps = 23/729 (3%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 175 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 Query: 176 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 235 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 Query: 236 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 295 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 Query: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 355 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 Query: 356 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 415 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 Query: 416 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 475 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP Sbjct: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480 Query: 476 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 535 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA Sbjct: 481 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 540 Query: 536 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 595 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY Sbjct: 541 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 600 Query: 596 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 655 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL Sbjct: 601 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 660 Query: 656 GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACL 715 GVPGVGGLGGIPPAAAAKAAKY GVAARPGFGLSPIFPGGACL Sbjct: 661 GVPGVGGLGGIPPAAAAKAAKY------------------GVAARPGFGLSPIFPGGACL 702 Query: 716 GKACGRKRK 724 GKACGRKRK Sbjct: 703 GKACGRKRK 711 >gi|126352322 elastin isoform c precursor [Homo sapiens] Length = 692 Score = 1347 bits (3487), Expect = 0.0 Identities = 687/729 (94%), Positives = 687/729 (94%), Gaps = 42/729 (5%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 175 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 Query: 176 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 235 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 Query: 236 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 295 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 Query: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 355 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 Query: 356 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 415 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 Query: 416 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 475 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVP Sbjct: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVP 461 Query: 476 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 535 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA Sbjct: 462 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 521 Query: 536 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 595 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY Sbjct: 522 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 581 Query: 596 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 655 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL Sbjct: 582 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 641 Query: 656 GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACL 715 GVPGVGGLGGIPPAAAAKAAKY GVAARPGFGLSPIFPGGACL Sbjct: 642 GVPGVGGLGGIPPAAAAKAAKY------------------GVAARPGFGLSPIFPGGACL 683 Query: 716 GKACGRKRK 724 GKACGRKRK Sbjct: 684 GKACGRKRK 692 >gi|126352700 elastin isoform b precursor [Homo sapiens] Length = 677 Score = 1325 bits (3430), Expect = 0.0 Identities = 677/724 (93%), Positives = 677/724 (93%), Gaps = 47/724 (6%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP ALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP----------ALGPGG 50 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 51 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 110 Query: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP Sbjct: 111 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 170 Query: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG Sbjct: 171 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 230 Query: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT Sbjct: 231 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 290 Query: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP Sbjct: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 350 Query: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV Sbjct: 351 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 410 Query: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA 480 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVPGVGVA Sbjct: 411 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVPGVGVA 451 Query: 481 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 540 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL Sbjct: 452 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 511 Query: 541 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 600 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP Sbjct: 512 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 571 Query: 601 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 660 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV Sbjct: 572 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 631 Query: 661 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG 720 GGLGGIPPAAAAKAAKY GVAARPGFGLSPIFPGGACLGKACG Sbjct: 632 GGLGGIPPAAAAKAAKY------------------GVAARPGFGLSPIFPGGACLGKACG 673 Query: 721 RKRK 724 RKRK Sbjct: 674 RKRK 677 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 191 bits (484), Expect = 3e-48 Identities = 239/712 (33%), Positives = 264/712 (37%), Gaps = 90/712 (12%) Query: 23 PSRPG--GVPGAI-PGGVPGGVFYPGAG--LGALGG-GALGPGGKPLKPVPGGLAGAGLG 76 P PG G PG + P G+PG PGA GA G GA G G P P G G Sbjct: 289 PGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG---- 344 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV 136 FPGA+ G A + ++ G+ G PG G +AG PGA Sbjct: 345 ----------FPGAVGAKGEAGPQGP-RGSEGPQGVRGEPGPPGPAGAAGPA-GNPGADG 392 Query: 137 KPGKVPGVGLPGVYPGGVLPGARFP----GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV 192 +PG G PG+ PGAR P G G PG P G +P APG G Sbjct: 393 QPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG-PKGNSGEPGAPGSKGDTGAKGEP 451 Query: 193 GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 252 GP G P P G K G G P TG LP GP G G G G+P GV Sbjct: 452 GPVGVQGPPGPAGEEGKR----GARGEPGPTG-LP---GPPGERGGPGSRGFPGADGV-- 501 Query: 253 QAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAA 311 A A + G AG G AG PG G +PG G+ G G+P Sbjct: 502 ---AGPKGPAGERGSPGPAGPKGSPGEAGRPGEAG-LPGAKGLTGSPGSPGPDGKTGPPG 557 Query: 312 KAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPGVGVPGAGIPVVPGAGIPGAAVPGV 367 A + G P G GV+G PG AG PG AG VPG PGA P Sbjct: 558 PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGK----AGERGVPGP--PGAVGPAG 611 Query: 368 VSPEAAAKAA-AKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGV 426 EA A+ A G R G G P GF G G G PG AG PG GV Sbjct: 612 KDGEAGAQGPPGPAGPAGERGEQGPAGSP-------GFQGLP-GPAGPPGEAGKPGEQGV 663 Query: 427 PGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVA 486 PG G PG P + GV P A A A PG A Sbjct: 664 PGDLGAPG----PSGARGERGFPGERGVQGPPGPAGPRGANGA-----------PGNDGA 708 Query: 487 PGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVA--AAAKSAAKVAAKAQLRAA 543 G APG APG APG+ PG A G+ GP G A K A K +R Sbjct: 709 KGDAGAPG---APGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGL 765 Query: 544 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 603 G G PG G G +G G G PG PG A A PG Sbjct: 766 TG-PIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFA----GPPGAD 820 Query: 604 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG--VGGLGVPGVG 661 G GA G G G AGP A A G GA G G G G PG Sbjct: 821 GQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA 880 Query: 662 GLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGA 713 G G PP + A G G G GG G G A RPG P PG A Sbjct: 881 GRVG-PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPA 931 Score = 173 bits (438), Expect = 6e-43 Identities = 229/706 (32%), Positives = 261/706 (36%), Gaps = 118/706 (16%) Query: 23 PSRPG--GVPG-----AIPG--GVPGGVFYPG-AGL-GALG-GGALGPGGKPLKP----V 66 P RPG G PG +PG G+PG + G +GL GA G G GP G+P P Sbjct: 238 PGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA 297 Query: 67 PGGLAGAGLGAGLGAFPAVTFPGALVPGGV-----ADAAAAYKAAKAGAGLGGVPGVGGL 121 PG + GL G PGA P G A AA AG G PG G Sbjct: 298 PGQMGPRGLPGERGR------PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGA 351 Query: 122 GVSAGAVVPQPGAGVKPGKVPGV-GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 AG P+ G P V G G PG P G A PG PG G AP Sbjct: 352 KGEAGPQGPRGSEG--PQGVRGEPGPPG--PAGAAGPAGNPGADGQPGAKGANG----AP 403 Query: 181 GVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAA 239 G+ GA G PG GP G PG P G PK G G P G G G Sbjct: 404 GIAGA-PGFPGARGPSGPQGPGGPPG-----PK--GNSGEP----------GAPGSKGDT 445 Query: 240 GKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV 298 G G P GV GP A K A+ G G+ G G PG G PG G+AG Sbjct: 446 GAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRG-FPGADGVAGP 504 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAG 358 PA + P GP PG G PG G+PGA G Sbjct: 505 KGPAGERGSPG--------------PAGPKGSPGEAGRPGEA----GLPGA-------KG 539 Query: 359 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVA 418 + G+ PG P+ A + G RPG P GA G G +G G G A Sbjct: 540 LTGS--PGSPGPDGKTGPPGPAGQDG-RPG------PPGPPGARGQAGV-MGFPGPKGAA 589 Query: 419 GVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAA-AAAKAAAKAAQFGLVPGV 477 G PG G GV G PG + P + A G PA + A + F +PG Sbjct: 590 GEPGKAGERGVPGPPG-AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGP 648 Query: 478 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAA 536 PG PG PG APG A G PG GV GP G A + A Sbjct: 649 AGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGA 708 Query: 537 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 596 K AG PG G PGL G+PG AG+PG K + Sbjct: 709 KGD--------AGAPGAPGSQGAPGL---QGMPGERGAAGLPG----------PKGDRGD 747 Query: 597 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 656 A G G G G G+ G + GPA A + + G GA G G G G Sbjct: 748 AGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPG-DRGEPG 806 Query: 657 VPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 PG G G PP A + G G G G AG G A PG Sbjct: 807 PPGPAGFAG-PPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPG 851 Score = 170 bits (430), Expect = 5e-42 Identities = 242/720 (33%), Positives = 269/720 (37%), Gaps = 102/720 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAG-----AGLGA 77 P P G PG G+PG PG P G P P P GL G G Sbjct: 122 PRGPAGPPGR--DGIPGQPGLPG------------PPGPPGPPGPPGLGGNFAPQLSYGY 167 Query: 78 GLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGAG 135 + ++ PG + P G A G G PG G ++G + P+ PG Sbjct: 168 DEKSTGGISVPGPMGPSGPRGLPGP-PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPP 226 Query: 136 VKPGKVPGVGLPGVYPGGVLP----GAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIP 190 K G G PG PG P GAR PG LPG+ G G+ GA Sbjct: 227 GKNGDDGEAGKPG-RPGERGPPGPQGARGLPGTAGLPGMKGHRGFS----GLDGAKGDAG 281 Query: 191 GVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVA---GAAGKAGYPTG 247 GP G +PG P AP G GLP G+ P GP G GA G AG P Sbjct: 282 PAGPKG--EPGSP--GENGAPGQMGPRGLPGERGR-PGAPGPAGARGNDGATGAAGPPGP 336 Query: 248 TGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAA 307 T GP AK AG G G GV G PG PG G AG PA A Sbjct: 337 T--GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAAG---PAGNPGA 390 Query: 308 AAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG----AGIPVVPGA-GIPGA 362 A A G + G PGF PG G G PG G PG +G P PG+ G GA Sbjct: 391 DGQPGAKGANGAPG-IAGAPGF-PGARGPSGPQGPG-GPPGPKGNSGEPGAPGSKGDTGA 447 Query: 363 -AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP-----TYGVGAGGFPGFGVGVGGIPG 416 PG V + A + K GAR G G+P G G+ GFPG GV G G Sbjct: 448 KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG-ADGVAGPKG 506 Query: 417 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPG 476 AG G G G G PG P AK G+P A PG Sbjct: 507 PAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPG 566 Query: 477 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGV--AAAAKSAAK 533 PG GV PG G PG GV PG +GP G A A+ Sbjct: 567 PPGPPGARGQAGVMGFPG---PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPG 623 Query: 534 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 593 A A R G AG PG G+PG AG PG AG PG VPG L Sbjct: 624 PAGPAGERGEQG-PAGSPGF---QGLPG---PAGPPG---EAGKPGEQGVPGDL------ 667 Query: 594 KYGAAVPGVLGGLGALGGVGIPG--GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGL-GG 649 G G GA G G PG GV G GPA A A G GA G G Sbjct: 668 -------GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGS 720 Query: 650 LGVGGL-GVPGVGGLGGIPPA------AAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 G GL G+PG G G+P A K A G+ G GV G G G A PG Sbjct: 721 QGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGAD-GSPGKDGVRGLTGPIGPPGPAGAPG 779 Score = 166 bits (419), Expect = 9e-41 Identities = 243/795 (30%), Positives = 277/795 (34%), Gaps = 153/795 (19%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA--GLGALGG-------GALGPGGKPLK------PVP 67 P PGG PG P G G PG+ GA G G GP G+ K P P Sbjct: 420 PQGPGGPPG--PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGP 477 Query: 68 GGLAGAGL---GAGLGAFPAVTFPGALVPGGVAD-------AAAAYKAAKAGA-GLGGVP 116 GL G G G FP G P G A A +AG G G+P Sbjct: 478 TGLPGPPGERGGPGSRGFPGAD--GVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535 Query: 117 GVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR-------FPGVGVLPGV 169 G GL S G+ P G PG G PG PG PGAR FPG G Sbjct: 536 GAKGLTGSPGSPGPDGKTG-PPGPAGQDGRPGP-PGP--PGARGQAGVMGFPGPKGAAGE 591 Query: 170 PTGAGVK--PKAPGVGGAFAGIPGVGPFGGPQPGVPLGY-----PIKAPK---LPGGYGL 219 P AG + P PG G G G P P P G P +P LPG G Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGP 651 Query: 220 PYTTGK-----LPYGYGPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKFG 267 P GK +P G G +GA G+ G+P GV GP+ A A AK Sbjct: 652 PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGD 711 Query: 268 AGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL 322 AGA G G G+ G+PG +PG G G P A + K G + Sbjct: 712 AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPG--KDGVRGLTGPI 769 Query: 323 VPGGPGFGPGVVGVPGA----------GVPG----VGVPG-AGIPVVPGA-------GIP 360 P GP PG G G G PG G PG AG PGA G P Sbjct: 770 GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEP 829 Query: 361 G-------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGG 413 G A PG P GA+ G G P GA GFPG G G Sbjct: 830 GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPP----GATGFPG-AAGRVG 884 Query: 414 IPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGL 473 PG +G G G PG G G G P + A + + G P A + + A Sbjct: 885 PPGPSGNAGPPGPPGPAGKEG-GKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD--- 940 Query: 474 VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAA 532 G APG G+ GV PG G PG PG GP G + Sbjct: 941 --GPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGER---- 994 Query: 533 KVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKA 592 G PG +G PGL AG PG G PG PG + Sbjct: 995 ----------------GPPG---PMGPPGL---AGPPGESGREGAPGAEGSPGR-DGSPG 1031 Query: 593 AKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-- 650 AK G G GA G G PG V AG + A A G VGA G G Sbjct: 1032 AKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG 1091 Query: 651 ---------GVGGLGVPGVGGLGGI--PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAA 699 G G+ G G G+ PP + G +G G G G G Sbjct: 1092 PRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPG 1151 Query: 700 RPGF-GL-SPIFPGG 712 + G GL PI P G Sbjct: 1152 KDGLNGLPGPIGPPG 1166 Score = 151 bits (381), Expect = 2e-36 Identities = 226/716 (31%), Positives = 252/716 (35%), Gaps = 106/716 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG--------GALGPGGKPLKPVPGGLAGA 73 P+ P G PG G PG PGA GL G G GP G+ +P P G GA Sbjct: 516 PAGPKGSPGE--AGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGA 573 Query: 74 GLGAGLGAFP----AVTFPGAL----VPGGVADAAAAYKAAKAGA--------------- 110 AG+ FP A PG VPG A K +AGA Sbjct: 574 RGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGE 633 Query: 111 -GLGGVPGVGGLGVSAGAVVPQPGAGVKPGK--VPG-VGLPGVYPGGVLPGARFPGVGVL 166 G G PG GL AG PG KPG+ VPG +G PG P G FPG + Sbjct: 634 QGPAGSPGFQGLPGPAGP----PGEAGKPGEQGVPGDLGAPG--PSGARGERGFPGERGV 687 Query: 167 PGVPTGAGVKPK--APGVGGAF--AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYT 222 G P AG + APG GA AG PG P PG+ P G GLP Sbjct: 688 QGPPGPAGPRGANGAPGNDGAKGDAGAPGA-PGSQGAPGLQ-----GMPGERGAAGLPGP 741 Query: 223 TGKLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAG 281 G GP G G+ GK G TG +GP A A +G AG G G Sbjct: 742 KGDRGDA-GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPG 800 Query: 282 VPGVPGAIPGIGGIAGV----GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVP 337 G PG PG G AG G P A A G P GP G VG P Sbjct: 801 DRGEPGP-PGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAP 859 Query: 338 GA-------GVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYG--ARP 387 GA G PG G PGA V P A PG P + G RP Sbjct: 860 GAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRP 919 Query: 388 G-VGVGGIPTYG-----------VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV 435 G VG G P GA G PG G+ G GV G+PG G G G+PG Sbjct: 920 GEVGPPGPPGPAGEKGSPGADGPAGAPGTPG-PQGIAGQRGVVGLPGQRGERGFPGLPGP 978 Query: 436 GISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGV 495 P Q + A + G + PG +PG +PG G Sbjct: 979 SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGE 1038 Query: 496 GLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGL 553 G APG APG VG A G G A A V A G G G Sbjct: 1039 TGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGE 1098 Query: 554 GVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVG 613 G G+ G GL G PG G A+ A PG G G G G Sbjct: 1099 TGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAG-PRGPPGSAGAPGKDGLNG 1157 Query: 614 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPA 669 +PG + GP G G AG VG G PG G G P A Sbjct: 1158 LPGPIGPPGPR---------------GRTGDAG----PVGPPGPPGPPGPPGPPSA 1194 Score = 117 bits (292), Expect = 5e-26 Identities = 183/613 (29%), Positives = 206/613 (33%), Gaps = 117/613 (19%) Query: 156 PGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPG 215 PGA P P P G+ P G GP G P P G +PG Sbjct: 82 PGAEVPEGECCPVCPDGSE-SPTDQETTGVEGPKGDTGPRGPRGPAGPPG----RDGIPG 136 Query: 216 GYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLP 275 GLP GP G G G G G PQ + K+ Sbjct: 137 QPGLP----------GPPGPPGPPGPPGL--GGNFAPQLSYGYDEKST------------ 172 Query: 276 GVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVV 334 GG VPG P G G+ G G P + + GA+ + P GP PG Sbjct: 173 --GGISVPG-PMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKN 229 Query: 335 GVPG-AGVPG-------------VGVPG-AGIPVVPG----AGIPGA------------- 362 G G AG PG G+PG AG+P + G +G+ GA Sbjct: 230 GDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEP 289 Query: 363 ------AVPGVVSPE---------AAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF 407 PG + P A A GA G G PT G GFPG Sbjct: 290 GSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPG-PTGPAGPPGFPG- 347 Query: 408 GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGV-GTPAAAAAKAAA 466 VG G G G G G GV G PG P A AA A G G P A A A Sbjct: 348 AVGAKGEAGPQGPRGSEGPQGVRGEPG----PPGPAGAAGPAGNPGADGQPGAKGANGA- 402 Query: 467 KAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPG----VGVAPGIGPG 522 PG+ APG A G G G PG G APG G GP Sbjct: 403 --------PGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV 454 Query: 523 GVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA 582 GV A + K R G G+PG G PG G G+ G G Sbjct: 455 GVQGPPGPAGE-EGKRGARGEPG-PTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERG 512 Query: 583 VPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLV 642 PG A K + A PG G GA G G PG G A + G Sbjct: 513 SPGP-AGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPP 571 Query: 643 GAAGLGGL-----GVGGLGVPGVGGLGGI--PPAAAAKAAKYGAAGLGGVLGGAGQFPLG 695 GA G G+ G G PG G G+ PP A A K G AG G G AG P G Sbjct: 572 GARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG--PAG 629 Query: 696 -----GVAARPGF 703 G A PGF Sbjct: 630 ERGEQGPAGSPGF 642 Score = 106 bits (265), Expect = 7e-23 Identities = 153/447 (34%), Positives = 167/447 (37%), Gaps = 55/447 (12%) Query: 26 PGGVPGAIPGGVPG--GVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAG---------- 72 P G PG P G PG G P G G GA G G+P P P G AG Sbjct: 768 PIGPPG--PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA 825 Query: 73 ----AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV 128 GA A P A PG + + A AK G G PG G +AG V Sbjct: 826 KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAP--GAKGARGSAGPPGATGFPGAAGRV 883 Query: 129 VPQ-PGAGVKPGKVPGVGLP--GVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGA 185 P P P PG G P G A PG PG P AG K +PG G Sbjct: 884 GPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKG-SPGADGP 942 Query: 186 FAGIPGV-GPFG-GPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLPYGY----GPGG 234 AG PG GP G Q GV +G P + P LPG G P G P G GP G Sbjct: 943 -AGAPGTPGPQGIAGQRGV-VGLPGQRGERGFPGLPGPSGEPGKQG--PSGASGERGPPG 998 Query: 235 VAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGA--IPGI 292 G G AG P +G + A A GA G G AG PG PGA PG Sbjct: 999 PMGPPGLAGPPGESG--REGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGP 1056 Query: 293 GGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPGA 349 G AG G A A GA P GP G G G G+ G G G Sbjct: 1057 VGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGL 1116 Query: 350 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 409 P P G PG P S A + +A GA G+ G+P G G PG Sbjct: 1117 QGPPGP-PGSPGEQGPSGASGPAGPRGPPGSA--GAPGKDGLNGLP----GPIGPPG-PR 1168 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVG 436 G G G G PG G PG G P G Sbjct: 1169 GRTGDAGPVGPPGPPGPPGPPGPPSAG 1195 Score = 85.5 bits (210), Expect = 2e-16 Identities = 122/374 (32%), Positives = 140/374 (37%), Gaps = 45/374 (12%) Query: 23 PSRPGGVPGAI-----PG--------GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGG 69 P+ P G PG I PG G PG +PGA G +G GP G P P G Sbjct: 843 PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA-GRVGPP--GPSGNAGPPGPPG 899 Query: 70 LAGAGLGAG-LGAFPAVTFPGALVPGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSAG 126 AG G G G PG + P G A A AG G PG G+ G Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959 Query: 127 AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARF-----PGVGVLPGV--PTGAGVKPKA 179 VV PG + G PG+ P PG P PG PG+ P G + A Sbjct: 960 -VVGLPGQRGERG-FPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGA 1017 Query: 180 PGVGGAFA--GIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVA 236 PG G+ G PG G G P P G P AP PG G +G G G A Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAP-GAPGAPGPVGPAGKSGDR----GETGPA 1072 Query: 237 GAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 295 G AG G G GPQ + + G G G G PG PG+ PG G Sbjct: 1073 GPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGS-PGEQGP 1131 Query: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG----AGI 351 +G PA +A A GL GP PG G G P VG PG G Sbjct: 1132 SGASGPAGPRGPPGSAGAPGKDGLNGL--PGPIGPPGPRGRTGDAGP-VGPPGPPGPPGP 1188 Query: 352 PVVPGAGIPGAAVP 365 P P AG + +P Sbjct: 1189 PGPPSAGFDFSFLP 1202 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 182 bits (463), Expect = 7e-46 Identities = 227/700 (32%), Positives = 260/700 (37%), Gaps = 88/700 (12%) Query: 28 GVPGAI-PGGVPG--GVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFP 83 G PG + P G+PG G P GA G G GP G P P G G Sbjct: 318 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG----------- 366 Query: 84 AVTFPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVP 142 FPGA PG +A GA G G PG G AGA PG PG Sbjct: 367 ---FPGA--PGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS-GNPGTDGIPGAKG 420 Query: 143 GVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGV 202 G PG+ PG R P P G + PG+ G F G G P G P P Sbjct: 421 SAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAG-FKGEQG--PKGEPGPAG 477 Query: 203 PLGYPIKAPK--LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAA 259 P G P A + G G P G + GP G GA G G+P G+ GP+ A Sbjct: 478 PQGAPGPAGEEGKRGARGEPGGVGPI----GPPGERGAPGNRGFPGQDGLAGPKGAPGER 533 Query: 260 AKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 319 + AG G G G PG+PGA G G + A + + G Sbjct: 534 GPSGL---AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP 590 Query: 320 AGLVPGGPGFGPGVVGVPGAGVPGVGVPGA----GIPVVPGA-GIPGA-AVPGVVSPEAA 373 P G PGV+G PG G PG G+P PG G+PG G P Sbjct: 591 G---PQGARGQPGVMGFPGPKGAN-GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 646 Query: 374 AKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--GIPGVAGVPGVGGVPGVGG 431 A A + + GA G G+P G G PG G G G+PG AG PG+ G G G Sbjct: 647 AGPAGERGEQGAPGPSGFQGLP----GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERG 702 Query: 432 VPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGV 491 PG SP AQ + GTP K A+ A PG PG+ PG Sbjct: 703 FPGERGSPGAQGLQGPRGLP---GTPGTDGPKGASGPAG---PPGAQGPPGLQGMPGERG 756 Query: 492 APGVGLAPG-------VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 544 A G+ G G G G G+ IGP G A A +V +A Sbjct: 757 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 816 Query: 545 GLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA--KYGAAVPGV 602 GA PG G PG AG PG PGA A K A PG Sbjct: 817 ARGA-----------PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGP 865 Query: 603 LGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGG 662 G GA G G P GV G A A A G GAAG G G G PG G Sbjct: 866 QGPSGAPGPQG-PTGVTGPKGARGAQGPPGAT-----GFPGAAGRVG-PPGSNGNPGPPG 918 Query: 663 LGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 PP + K GA G G G AG+ L G A PG Sbjct: 919 ----PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPG 954 Score = 169 bits (429), Expect = 6e-42 Identities = 231/738 (31%), Positives = 265/738 (35%), Gaps = 91/738 (12%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAG----AGLGAG 78 P P G PG P G G PG + G GP G P KP G AG AG Sbjct: 211 PPGPAGAPG--PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 268 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKP 138 G A FPG GV Y G G PGV G S PG P Sbjct: 269 PGPQGARGFPGTPGLPGVK-GHRGYPGLDGAKGEAGAPGVKGESGS-------PGENGSP 320 Query: 139 GKVPGVGLPG----VYPGGVLPGARF----PGVGVLPGV--PTGAGVKPKAPGVGGAFAG 188 G + GLPG P G GAR PG PG P G P APG G Sbjct: 321 GPMGPRGLPGERGRTGPAGAA-GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 379 Query: 189 IPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGT 248 GP G P G P +P G G P T G +P G G G AG G+P Sbjct: 380 TGARGPEGAQGPRGEPGTP-GSPGPAGASGNPGTDG-IPGAKGSAGAPGIAGAPGFPGPR 437 Query: 249 GV-GPQAA---------------AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 G GPQ A A + K G AG G AG G GA Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 497 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPGA- 349 GG+ +G P A + G A GP PG G G AG G G PG Sbjct: 498 GGVGPIGPPGERGAPGNRGFPGQDGLA------GPKGAPGERGPSGLAGPKGANGDPGRP 551 Query: 350 GIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 408 G P +PGA G+ G PG P+ + + G RPG P GA G PG Sbjct: 552 GEPGLPGARGLTGR--PGDAGPQGKVGPSGAPGEDG-RPG------PPGPQGARGQPGV- 601 Query: 409 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 468 +G G G G PG G G+ G PG+ P A G + A Sbjct: 602 MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 661 Query: 469 AQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGV 524 + F +PG PG G PG PG APG+ G PG +PG GP G+ Sbjct: 662 SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGL 721 Query: 525 AA-----AAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL-----GVG----AGVPG 570 K A+ A + GL G+PG G+ G VG G PG Sbjct: 722 PGTPGTDGPKGASGPAGPPGAQGPPGL-QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780 Query: 571 LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG------VGIPGGVVGAGPA 624 G G+ G PG A A K PG G GA G G PG AGP Sbjct: 781 KDGGRGLTGPIGPPGP-AGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 839 Query: 625 AAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGG 684 A A + + G G AG G G G PG G G+ A+ A+ G G G Sbjct: 840 GADGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQGPTGVTGPKGARGAQ-GPPGATG 897 Query: 685 VLGGAGQFPLGGVAARPG 702 G AG+ G PG Sbjct: 898 FPGAAGRVGPPGSNGNPG 915 Score = 162 bits (411), Expect = 8e-40 Identities = 235/767 (30%), Positives = 268/767 (34%), Gaps = 134/767 (17%) Query: 26 PGGVPGAI-PGGVPGGVFYPGAG-----LGALGG-GALGPGGKPLKPVPGGLAGAGLGAG 78 P G PG + P G PG PGA GA G GA GP G+P P G AGA G Sbjct: 352 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 411 Query: 79 LGAFP-------------AVTFPGALVPGGVADAAAAY--KAAKAGAGLGGVPGVGGLGV 123 P A FPG P G A K G+ G G G Sbjct: 412 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 471 Query: 124 SAGAVVPQ--PGAGVKPGKVPGVGLPG-VYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKA 179 G PQ PG + GK G PG V P G PG R PG PG AG K A Sbjct: 472 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGP-PGERGAPGNRGFPGQDGLAGPKG-A 529 Query: 180 PGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL-PYG-YGPGGVAG 237 PG G +G+ G G PG P P LPG GL G P G GP G G Sbjct: 530 PGERGP-SGLAGPKGANG-DPGRP-----GEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 582 Query: 238 AAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGI 295 G+ G P GPQ A GA G G G+PG PG +PG G Sbjct: 583 EDGRPGPP-----GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 637 Query: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGVGVPGAGIPV 353 G P A A + + GA PG GF PG G PG G G PG Sbjct: 638 TGAAGPPGPAGPAG--ERGEQGA-----PGPSGFQGLPGPPGPPGEG----GKPG----- 681 Query: 354 VPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG 412 G+PG A PG+V P + GA+ G G+P G P G Sbjct: 682 --DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP--GTPGTDGPKGASGPA 737 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVG--------ISPEAQAAAAAKAAKYGVGTPAAAAAKA 464 G PG G PG+ G+PG G G+ + + A K G+ P A Sbjct: 738 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA 797 Query: 465 AAKAAQFGL-VPGVGVAPGVGVAPG----------VGVA--PGVGLAPGVGVAPGVGVAP 511 A + + PG + G APG G A PG PG G Sbjct: 798 GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK 857 Query: 512 GVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVP 569 G APG GP G K A GA G PG VG PG G P Sbjct: 858 GDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 917 Query: 570 GLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA-GPAAA 626 G PG P K A+ + PG G G G G PG G G GP+ A Sbjct: 918 G------PPG----PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA 967 Query: 627 AAAAKAAAKAAQFGLVGAAGL-------------------GGLGVGG-------LGVPGV 660 A Q G+VG G G G G +G PG+ Sbjct: 968 EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGL 1027 Query: 661 GGLGGIP-----PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 G G P P A + GAAG+ G G G G PG Sbjct: 1028 TGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPG 1074 Score = 162 bits (409), Expect = 1e-39 Identities = 238/719 (33%), Positives = 264/719 (36%), Gaps = 107/719 (14%) Query: 54 GALGPGGKPLKPVPGGLAG-------------AGLGAGLGAFPAVTFP-GALVPGGVADA 99 G GP G P P P GL G AG GA LG P G P G A A Sbjct: 159 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG-GAQLGVMQGPMGPMGPRGPPGPAGA 217 Query: 100 AAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY----PGGVL 155 + + G G PGV G G PG KPG G PG P G Sbjct: 218 PGP-QGFQGNPGEPGEPGVSGPMGPRG----PPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272 Query: 156 PGARFPGVGVLPGVPTGAGVKPKAPGVGGA--FAGIPGV-GPFGGPQPGVPLGYPIKAPK 212 FPG LPGV G PG+ GA AG PGV G G P +P Sbjct: 273 GARGFPGTPGLPGVKGHRGY----PGLDGAKGEAGAPGVKGESGSPGEN-------GSPG 321 Query: 213 LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFGA 268 G GLP G+ GP G AGA G G P G VGP AK A Sbjct: 322 PMGPRGLPGERGRT----GPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 377 Query: 269 GAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG 328 G G G G G PG PG G AG A+ AK A A + G PG Sbjct: 378 GPTGARGPEGAQGPRGEPGT-PGSPGPAG----ASGNPGTDGIPGAKGSAGAPGIAGAPG 432 Query: 329 FGPGVVGVPG-AGVPG-VGVPG-AGIPVVPG-AGIPG-AAVPGVVSPEAAAKAAAKAAKY 383 F PG G PG G G +G G G P + G G G PG P+ A A + K Sbjct: 433 F-PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491 Query: 384 GAR--PGVGVGGI-PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPE 440 GAR PG GVG I P GA G GF G G+ G G PG G G+ G G P Sbjct: 492 GARGEPG-GVGPIGPPGERGAPGNRGF-PGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 549 Query: 441 AQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPG 500 A+ G P A + K G PG PG G PGV PG Sbjct: 550 RPGEPGLPGARGLTGRPGDAGPQ--GKVGPSG-APGEDGRPGPPGPQGARGQPGVMGFPG 606 Query: 501 VGVA---PGVGVAPGVGVAPGI-------GPGGVAAAAKSAAKVAAKAQLRAAAGLG--- 547 A PG G+ APG+ G G A A + + A G Sbjct: 607 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG 666 Query: 548 ----AGIPGLGVGVGVPGLGVGAGVPGLGVG----AGVPGFGAVPGALAAAKAAKYGAAV 599 G PG G G G+ AG PGL VG G PG PGA + + Sbjct: 667 LPGPPGPPGEGGKPGDQGVPGEAGAPGL-VGPRGERGFPGERGSPGA-QGLQGPRGLPGT 724 Query: 600 PGVLGGLGALGGVGIPG--------GVVGAGPAAAAAAAKA-AAKAAQFGLVGAAGL-GG 649 PG G GA G G PG G+ G AA A K + G GA G GG Sbjct: 725 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 784 Query: 650 LGV-GGLGVPGVGGLGGI-----PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 G+ G +G PG G G PP A A GA G G G G G A PG Sbjct: 785 RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP---AGFAGPPG 840 Score = 139 bits (351), Expect = 7e-33 Identities = 234/772 (30%), Positives = 271/772 (35%), Gaps = 135/772 (17%) Query: 26 PGGV-PGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA-GLGAGLGA 81 PGGV P PG G PG +PG G GP G P + P GLAG G G Sbjct: 497 PGGVGPIGPPGERGAPGNRGFPGQD------GLAGPKGAPGERGPSGLAGPKGANGDPGR 550 Query: 82 FPAVTFPGAL-VPGGVADAAAAYKAAKAGA----GLGGVPGVGGLGVSAGAV-VPQP-GA 134 PGA + G DA K +GA G G PG G G + P P GA Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 610 Query: 135 GVKPGKVPGVGLPGVYPGGVLPG-------ARFPGVGVLPGVPTGAGVKPKAPGVGGAFA 187 +PGK GLPG LPG A PG P P G + APG G F Sbjct: 611 NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG----PAGPAGERGEQGAPGPSG-FQ 665 Query: 188 GIPGV-GPFG-GPQPG---VP--LGYP-IKAPK----LPGGYGLPYTTGK-----LPYGY 230 G+PG GP G G +PG VP G P + P+ PG G P G LP Sbjct: 666 GLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTP 725 Query: 231 GPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVP 283 G G GA+G AG P G G + AA A + G G G G Sbjct: 726 GTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR 785 Query: 284 GVPGAI--PGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVP 337 G+ G I PG G G VG P A +A A + G P G PG G P Sbjct: 786 GLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP 845 Query: 338 GA-------------GVPGV----GVPGAGIPV-------------VPGA-GIPGAA--- 363 GA G PG G PG P PGA G PGAA Sbjct: 846 GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV 905 Query: 364 ----VPGVVSPEAAAKAAAKAAKYGAR-----------PGV-GVGGIPTYG--------V 399 G P + K GAR PG+ G G P Sbjct: 906 GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPS 965 Query: 400 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAA 459 GA G PG G+ G G+ G+PG G G G+PG P Q A A + G P Sbjct: 966 GAEGPPG-PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDR---GPPGP 1021 Query: 460 AAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI 519 A PG +PG PG A GV G A G APG +P Sbjct: 1022 VGPPGLTGPAG---EPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP-- 1076 Query: 520 GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 578 GP G + A+ + + GA GI G G G G GL G Sbjct: 1077 GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1136 Query: 579 GFGAVPGAL-------AAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAA 630 G +PG A+ A G PG +G G G GIPG + GP + Sbjct: 1137 GLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGET 1196 Query: 631 KAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGL 682 A G G G G G+ G+G P A A GL Sbjct: 1197 GPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGL 1248 Score = 132 bits (331), Expect = 1e-30 Identities = 190/595 (31%), Positives = 214/595 (35%), Gaps = 79/595 (13%) Query: 167 PGVPTGAGVKPKAPGVGGAFAGIPG-----VGPFGGPQPGVPLGY--PIKAPKLPGGYGL 219 P PT PG G G PG VGP G P P P G P G G Sbjct: 87 PICPTDLATASGQPGPKGQ-KGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGA 145 Query: 220 PYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVL----- 274 P G+ PG G G G P G+G AA A K G GV+ Sbjct: 146 PGPRGRDGEPGTPGN-PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204 Query: 275 -------PGVGGA-------GVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAA 319 PG GA G PG PG PG+ G G G P +A K G A Sbjct: 205 PMGPRGPPGPAGAPGPQGFQGNPGEPGE-PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA 263 Query: 320 AGLVPGGP----GFGPGVVGVPGA----GVPGV-GVPG-AGIPVVPG-AGIPGA-AVPGV 367 P GP GF PG G+PG G PG+ G G AG P V G +G PG PG Sbjct: 264 GERGPPGPQGARGF-PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322 Query: 368 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG-----FGVGVGGIPGVAGVPG 422 + P + GA G G P G G PG G G G PG G G Sbjct: 323 MGPRGLPGERGRTGPAGAAGARGNDGQP----GPAGPPGPVGPAGGPGFPGAPGAKGEAG 378 Query: 423 VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPG 482 G G G G P + A GT AK +A A PG+ APG Sbjct: 379 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA------PGIAGAPG 432 Query: 483 VGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGV--AAAAKSAAKVAAKAQ 539 PG PG A G G PG+ G GP G A + A A + Sbjct: 433 F---PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEG 489 Query: 540 LRAAAGLGAGIPGLGV--GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGA 597 R A G G+ +G G PG G GL G PG P LA K A Sbjct: 490 KRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG-PSGLAGPKGANGDP 548 Query: 598 AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGV 657 PG G GA G G PG AGP + A + + G G G G G +G Sbjct: 549 GRPGEPGLPGARGLTGRPG---DAGPQGKVGPSGAPGEDGRPGPPGPQGARG-QPGVMGF 604 Query: 658 PGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGG 712 PG G G P A K GA GL G+ G G+ G A PG P P G Sbjct: 605 PGPKGANGEPGKAGEKGLP-GAPGLRGLPGKDGE---TGAAGPPG----PAGPAG 651 Score = 122 bits (307), Expect = 9e-28 Identities = 163/539 (30%), Positives = 184/539 (34%), Gaps = 70/539 (12%) Query: 194 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQ 253 PFG P P + + PG G G + GP G G G AG GP+ Sbjct: 81 PFGECCPICPTDLATASGQ-PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQ-----GPR 134 Query: 254 AAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKA 313 + A G G G G PG PG PG G+ G A A Sbjct: 135 GDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGP-PGPPGLGGNFAAQMAGGFDEKAGG 193 Query: 314 AKYGAAAG-LVPGGPGFGPGVVGVPGA----GVPGV-GVPGAGIPVVPGAGIPGAAVPGV 367 A+ G G + P GP PG G PG G PG G PG P+ P G PG PG Sbjct: 194 AQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP-RGPPGP--PGK 250 Query: 368 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVP 427 + A KA + G G G P G G PG G G PG+ G G G P Sbjct: 251 PGDDGEAGKPGKAGERGPPGPQGARGFP----GTPGLPGVK-GHRGYPGLDGAKGEAGAP 305 Query: 428 GV---GGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVG 484 GV G PG SP + G AA A+ G PG Sbjct: 306 GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGAR------------GNDGQPGPA 353 Query: 485 VAPG-VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAA 543 PG VG A G G G G G GP G S A Sbjct: 354 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA------- 406 Query: 544 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAK--AAKYGAAVPG 601 +G PG G+PG AG PG+ G PG PG A K PG Sbjct: 407 ----SGNPGTD---GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 459 Query: 602 VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 661 + G G G G PG AGP A A K GA G G GVG +G PG Sbjct: 460 IAGFKGEQGPKGEPGP---AGPQGAPGPAGEEGKR------GARGEPG-GVGPIGPPGER 509 Query: 662 GLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG 720 G G G GL G G G+ G+A G P PG L A G Sbjct: 510 GAPG-------NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 561 Score = 107 bits (267), Expect = 4e-23 Identities = 149/455 (32%), Positives = 167/455 (36%), Gaps = 54/455 (11%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P P G GA G G V PG A GA G G+ P P G AG G Sbjct: 790 PIGPPGPAGA--NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ--- 844 Query: 83 PAVTFPGALVPGGVA----DAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVK 137 PGA G A DA A +GA G G GV G + GA P PGA Sbjct: 845 -----PGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-PGATGF 898 Query: 138 PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFG 196 PG VG PG PG PG G P GA PG AG PG+ GP G Sbjct: 899 PGAAGRVGPPGSNGNPGPPGP--PGPSGKDG-PKGARGDSGPPGR----AGEPGLQGPAG 951 Query: 197 GP----QPGVPLGYPIKAPKLPGGY-------GLPYTTGKLPYGYGPGGVAGAAGKAGYP 245 P +PG + P P G GLP G+ + G G +G GK G P Sbjct: 952 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP-GLPGPSGEPGKQGAP 1010 Query: 246 TGTG-------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV 298 +G VGP A + + GA G G AGV G G +G Sbjct: 1011 GASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAP 1070 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPG-- 356 G P + A K G A P GP G G+ G P AG P G Sbjct: 1071 GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK 1130 Query: 357 --AGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG-FGV--- 409 G G +PG P A+ A G R G G P+ GA G PG G Sbjct: 1131 GHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVG-PSGKDGANGIPGPIGPPGP 1189 Query: 410 -GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 G G G AG PG G PG G PG GI A A Sbjct: 1190 RGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFA 1224 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 182 bits (463), Expect = 7e-46 Identities = 227/700 (32%), Positives = 260/700 (37%), Gaps = 88/700 (12%) Query: 28 GVPGAI-PGGVPG--GVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFP 83 G PG + P G+PG G P GA G G GP G P P G G Sbjct: 249 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG----------- 297 Query: 84 AVTFPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVP 142 FPGA PG +A GA G G PG G AGA PG PG Sbjct: 298 ---FPGA--PGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS-GNPGTDGIPGAKG 351 Query: 143 GVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGV 202 G PG+ PG R P P G + PG+ G F G G P G P P Sbjct: 352 SAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAG-FKGEQG--PKGEPGPAG 408 Query: 203 PLGYPIKAPK--LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAA 259 P G P A + G G P G + GP G GA G G+P G+ GP+ A Sbjct: 409 PQGAPGPAGEEGKRGARGEPGGVGPI----GPPGERGAPGNRGFPGQDGLAGPKGAPGER 464 Query: 260 AKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 319 + AG G G G PG+PGA G G + A + + G Sbjct: 465 GPSGL---AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP 521 Query: 320 AGLVPGGPGFGPGVVGVPGAGVPGVGVPGA----GIPVVPGA-GIPGA-AVPGVVSPEAA 373 P G PGV+G PG G PG G+P PG G+PG G P Sbjct: 522 G---PQGARGQPGVMGFPGPKGAN-GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 577 Query: 374 AKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--GIPGVAGVPGVGGVPGVGG 431 A A + + GA G G+P G G PG G G G+PG AG PG+ G G G Sbjct: 578 AGPAGERGEQGAPGPSGFQGLP----GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERG 633 Query: 432 VPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGV 491 PG SP AQ + GTP K A+ A PG PG+ PG Sbjct: 634 FPGERGSPGAQGLQGPRGLP---GTPGTDGPKGASGPAG---PPGAQGPPGLQGMPGERG 687 Query: 492 APGVGLAPG-------VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 544 A G+ G G G G G+ IGP G A A +V +A Sbjct: 688 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 747 Query: 545 GLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA--KYGAAVPGV 602 GA PG G PG AG PG PGA A K A PG Sbjct: 748 ARGA-----------PGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGP 796 Query: 603 LGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGG 662 G GA G G P GV G A A A G GAAG G G G PG G Sbjct: 797 QGPSGAPGPQG-PTGVTGPKGARGAQGPPGAT-----GFPGAAGRVG-PPGSNGNPGPPG 849 Query: 663 LGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 PP + K GA G G G AG+ L G A PG Sbjct: 850 ----PPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPG 885 Score = 169 bits (429), Expect = 6e-42 Identities = 231/738 (31%), Positives = 265/738 (35%), Gaps = 91/738 (12%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAG----AGLGAG 78 P P G PG P G G PG + G GP G P KP G AG AG Sbjct: 142 PPGPAGAPG--PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 199 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKP 138 G A FPG GV Y G G PGV G S PG P Sbjct: 200 PGPQGARGFPGTPGLPGVK-GHRGYPGLDGAKGEAGAPGVKGESGS-------PGENGSP 251 Query: 139 GKVPGVGLPG----VYPGGVLPGARF----PGVGVLPGV--PTGAGVKPKAPGVGGAFAG 188 G + GLPG P G GAR PG PG P G P APG G Sbjct: 252 GPMGPRGLPGERGRTGPAGAA-GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 310 Query: 189 IPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGT 248 GP G P G P +P G G P T G +P G G G AG G+P Sbjct: 311 TGARGPEGAQGPRGEPGTP-GSPGPAGASGNPGTDG-IPGAKGSAGAPGIAGAPGFPGPR 368 Query: 249 GV-GPQAA---------------AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 G GPQ A A + K G AG G AG G GA Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 428 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPGA- 349 GG+ +G P A + G A GP PG G G AG G G PG Sbjct: 429 GGVGPIGPPGERGAPGNRGFPGQDGLA------GPKGAPGERGPSGLAGPKGANGDPGRP 482 Query: 350 GIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 408 G P +PGA G+ G PG P+ + + G RPG P GA G PG Sbjct: 483 GEPGLPGARGLTGR--PGDAGPQGKVGPSGAPGEDG-RPG------PPGPQGARGQPGV- 532 Query: 409 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 468 +G G G G PG G G+ G PG+ P A G + A Sbjct: 533 MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 592 Query: 469 AQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGV 524 + F +PG PG G PG PG APG+ G PG +PG GP G+ Sbjct: 593 SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGL 652 Query: 525 AA-----AAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL-----GVG----AGVPG 570 K A+ A + GL G+PG G+ G VG G PG Sbjct: 653 PGTPGTDGPKGASGPAGPPGAQGPPGL-QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 711 Query: 571 LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG------VGIPGGVVGAGPA 624 G G+ G PG A A K PG G GA G G PG AGP Sbjct: 712 KDGGRGLTGPIGPPGP-AGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 770 Query: 625 AAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGG 684 A A + + G G AG G G G PG G G+ A+ A+ G G G Sbjct: 771 GADGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQGPTGVTGPKGARGAQ-GPPGATG 828 Query: 685 VLGGAGQFPLGGVAARPG 702 G AG+ G PG Sbjct: 829 FPGAAGRVGPPGSNGNPG 846 Score = 162 bits (411), Expect = 8e-40 Identities = 235/767 (30%), Positives = 268/767 (34%), Gaps = 134/767 (17%) Query: 26 PGGVPGAI-PGGVPGGVFYPGAG-----LGALGG-GALGPGGKPLKPVPGGLAGAGLGAG 78 P G PG + P G PG PGA GA G GA GP G+P P G AGA G Sbjct: 283 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 342 Query: 79 LGAFP-------------AVTFPGALVPGGVADAAAAY--KAAKAGAGLGGVPGVGGLGV 123 P A FPG P G A K G+ G G G Sbjct: 343 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 402 Query: 124 SAGAVVPQ--PGAGVKPGKVPGVGLPG-VYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKA 179 G PQ PG + GK G PG V P G PG R PG PG AG K A Sbjct: 403 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGP-PGERGAPGNRGFPGQDGLAGPKG-A 460 Query: 180 PGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL-PYG-YGPGGVAG 237 PG G +G+ G G PG P P LPG GL G P G GP G G Sbjct: 461 PGERGP-SGLAGPKGANG-DPGRP-----GEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 513 Query: 238 AAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGI 295 G+ G P GPQ A GA G G G+PG PG +PG G Sbjct: 514 EDGRPGPP-----GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 568 Query: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGVGVPGAGIPV 353 G P A A + + GA PG GF PG G PG G G PG Sbjct: 569 TGAAGPPGPAGPAG--ERGEQGA-----PGPSGFQGLPGPPGPPGEG----GKPG----- 612 Query: 354 VPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG 412 G+PG A PG+V P + GA+ G G+P G P G Sbjct: 613 --DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP--GTPGTDGPKGASGPA 668 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVG--------ISPEAQAAAAAKAAKYGVGTPAAAAAKA 464 G PG G PG+ G+PG G G+ + + A K G+ P A Sbjct: 669 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA 728 Query: 465 AAKAAQFGL-VPGVGVAPGVGVAPG----------VGVA--PGVGLAPGVGVAPGVGVAP 511 A + + PG + G APG G A PG PG G Sbjct: 729 GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK 788 Query: 512 GVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVP 569 G APG GP G K A GA G PG VG PG G P Sbjct: 789 GDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP 848 Query: 570 GLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA-GPAAA 626 G PG P K A+ + PG G G G G PG G G GP+ A Sbjct: 849 G------PPG----PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA 898 Query: 627 AAAAKAAAKAAQFGLVGAAGL-------------------GGLGVGG-------LGVPGV 660 A Q G+VG G G G G +G PG+ Sbjct: 899 EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGL 958 Query: 661 GGLGGIP-----PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 G G P P A + GAAG+ G G G G PG Sbjct: 959 TGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPG 1005 Score = 162 bits (409), Expect = 1e-39 Identities = 238/719 (33%), Positives = 264/719 (36%), Gaps = 107/719 (14%) Query: 54 GALGPGGKPLKPVPGGLAG-------------AGLGAGLGAFPAVTFP-GALVPGGVADA 99 G GP G P P P GL G AG GA LG P G P G A A Sbjct: 90 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG-GAQLGVMQGPMGPMGPRGPPGPAGA 148 Query: 100 AAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY----PGGVL 155 + + G G PGV G G PG KPG G PG P G Sbjct: 149 PGP-QGFQGNPGEPGEPGVSGPMGPRG----PPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203 Query: 156 PGARFPGVGVLPGVPTGAGVKPKAPGVGGA--FAGIPGV-GPFGGPQPGVPLGYPIKAPK 212 FPG LPGV G PG+ GA AG PGV G G P +P Sbjct: 204 GARGFPGTPGLPGVKGHRGY----PGLDGAKGEAGAPGVKGESGSPGEN-------GSPG 252 Query: 213 LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFGA 268 G GLP G+ GP G AGA G G P G VGP AK A Sbjct: 253 PMGPRGLPGERGRT----GPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA 308 Query: 269 GAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG 328 G G G G G PG PG G AG A+ AK A A + G PG Sbjct: 309 GPTGARGPEGAQGPRGEPGT-PGSPGPAG----ASGNPGTDGIPGAKGSAGAPGIAGAPG 363 Query: 329 FGPGVVGVPG-AGVPG-VGVPG-AGIPVVPG-AGIPG-AAVPGVVSPEAAAKAAAKAAKY 383 F PG G PG G G +G G G P + G G G PG P+ A A + K Sbjct: 364 F-PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 422 Query: 384 GAR--PGVGVGGI-PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPE 440 GAR PG GVG I P GA G GF G G+ G G PG G G+ G G P Sbjct: 423 GARGEPG-GVGPIGPPGERGAPGNRGF-PGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 480 Query: 441 AQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPG 500 A+ G P A + K G PG PG G PGV PG Sbjct: 481 RPGEPGLPGARGLTGRPGDAGPQ--GKVGPSG-APGEDGRPGPPGPQGARGQPGVMGFPG 537 Query: 501 VGVA---PGVGVAPGVGVAPGI-------GPGGVAAAAKSAAKVAAKAQLRAAAGLG--- 547 A PG G+ APG+ G G A A + + A G Sbjct: 538 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG 597 Query: 548 ----AGIPGLGVGVGVPGLGVGAGVPGLGVG----AGVPGFGAVPGALAAAKAAKYGAAV 599 G PG G G G+ AG PGL VG G PG PGA + + Sbjct: 598 LPGPPGPPGEGGKPGDQGVPGEAGAPGL-VGPRGERGFPGERGSPGA-QGLQGPRGLPGT 655 Query: 600 PGVLGGLGALGGVGIPG--------GVVGAGPAAAAAAAKA-AAKAAQFGLVGAAGL-GG 649 PG G GA G G PG G+ G AA A K + G GA G GG Sbjct: 656 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 715 Query: 650 LGV-GGLGVPGVGGLGGI-----PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 G+ G +G PG G G PP A A GA G G G G G A PG Sbjct: 716 RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP---AGFAGPPG 771 Score = 139 bits (351), Expect = 7e-33 Identities = 234/772 (30%), Positives = 271/772 (35%), Gaps = 135/772 (17%) Query: 26 PGGV-PGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA-GLGAGLGA 81 PGGV P PG G PG +PG G GP G P + P GLAG G G Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQD------GLAGPKGAPGERGPSGLAGPKGANGDPGR 481 Query: 82 FPAVTFPGAL-VPGGVADAAAAYKAAKAGA----GLGGVPGVGGLGVSAGAV-VPQP-GA 134 PGA + G DA K +GA G G PG G G + P P GA Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 541 Query: 135 GVKPGKVPGVGLPGVYPGGVLPG-------ARFPGVGVLPGVPTGAGVKPKAPGVGGAFA 187 +PGK GLPG LPG A PG P P G + APG G F Sbjct: 542 NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG----PAGPAGERGEQGAPGPSG-FQ 596 Query: 188 GIPGV-GPFG-GPQPG---VP--LGYP-IKAPK----LPGGYGLPYTTGK-----LPYGY 230 G+PG GP G G +PG VP G P + P+ PG G P G LP Sbjct: 597 GLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTP 656 Query: 231 GPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVP 283 G G GA+G AG P G G + AA A + G G G G Sbjct: 657 GTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR 716 Query: 284 GVPGAI--PGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVP 337 G+ G I PG G G VG P A +A A + G P G PG G P Sbjct: 717 GLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQP 776 Query: 338 GA-------------GVPGV----GVPGAGIPV-------------VPGA-GIPGAA--- 363 GA G PG G PG P PGA G PGAA Sbjct: 777 GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV 836 Query: 364 ----VPGVVSPEAAAKAAAKAAKYGAR-----------PGV-GVGGIPTYG--------V 399 G P + K GAR PG+ G G P Sbjct: 837 GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPS 896 Query: 400 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAA 459 GA G PG G+ G G+ G+PG G G G+PG P Q A A + G P Sbjct: 897 GAEGPPG-PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDR---GPPGP 952 Query: 460 AAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI 519 A PG +PG PG A GV G A G APG +P Sbjct: 953 VGPPGLTGPAG---EPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP-- 1007 Query: 520 GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 578 GP G + A+ + + GA GI G G G G GL G Sbjct: 1008 GPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1067 Query: 579 GFGAVPGAL-------AAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAA 630 G +PG A+ A G PG +G G G GIPG + GP + Sbjct: 1068 GLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGET 1127 Query: 631 KAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGL 682 A G G G G G+ G+G P A A GL Sbjct: 1128 GPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGL 1179 Score = 130 bits (326), Expect = 6e-30 Identities = 188/588 (31%), Positives = 213/588 (36%), Gaps = 79/588 (13%) Query: 174 GVKPKAPGVGGAFAGIPG-----VGPFGGPQPGVPLGY--PIKAPKLPGGYGLPYTTGKL 226 G + PG G G PG VGP G P P P G P G G P G+ Sbjct: 25 GQDVRQPGPKGQ-KGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 83 Query: 227 PYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVL------------ 274 PG G G G P G+G AA A K G GV+ Sbjct: 84 GEPGTPGN-PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 142 Query: 275 PGVGGA-------GVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGG 326 PG GA G PG PG PG+ G G G P +A K G A P G Sbjct: 143 PGPAGAPGPQGFQGNPGEPGE-PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG 201 Query: 327 P----GFGPGVVGVPGA----GVPGV-GVPG-AGIPVVPG-AGIPGA-AVPGVVSPEAAA 374 P GF PG G+PG G PG+ G G AG P V G +G PG PG + P Sbjct: 202 PQGARGF-PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 260 Query: 375 KAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG-----FGVGVGGIPGVAGVPGVGGVPGV 429 + GA G G P G G PG G G G PG G G G G Sbjct: 261 GERGRTGPAGAAGARGNDGQP----GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316 Query: 430 GGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGV 489 G G P + A GT AK +A A PG+ APG PG Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA------PGIAGAPGF---PGP 367 Query: 490 GVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGV--AAAAKSAAKVAAKAQLRAAAGL 546 PG A G G PG+ G GP G A + A A + R A G Sbjct: 368 RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE 427 Query: 547 GAGIPGLGV--GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLG 604 G+ +G G PG G GL G PG P LA K A PG G Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG-PSGLAGPKGANGDPGRPGEPG 486 Query: 605 GLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLG 664 GA G G PG AGP + A + + G G G G G +G PG G Sbjct: 487 LPGARGLTGRPG---DAGPQGKVGPSGAPGEDGRPGPPGPQGARG-QPGVMGFPGPKGAN 542 Query: 665 GIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGG 712 G P A K GA GL G+ G G+ G A PG P P G Sbjct: 543 GEPGKAGEKGLP-GAPGLRGLPGKDGE---TGAAGPPG----PAGPAG 582 Score = 122 bits (305), Expect = 2e-27 Identities = 158/519 (30%), Positives = 177/519 (34%), Gaps = 69/519 (13%) Query: 214 PGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGV 273 PG G G + GP G G G AG GP+ + A G G Sbjct: 31 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQ-----GPRGDRGDKGEKGAPGPRGRDGE 85 Query: 274 LPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAG-LVPGGPGFGPG 332 G G PG PG PG G+ G A A A+ G G + P GP PG Sbjct: 86 PGTPGNPGPPGPPGP-PGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 144 Query: 333 VVGVPGA----GVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARP 387 G PG G PG G PG P+ P G PG PG + A KA + G Sbjct: 145 PAGAPGPQGFQGNPGEPGEPGVSGPMGP-RGPPGP--PGKPGDDGEAGKPGKAGERGPPG 201 Query: 388 GVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGV---GGVPGVGISPEAQAA 444 G G P G G PG G G PG+ G G G PGV G PG SP Sbjct: 202 PQGARGFP----GTPGLPGVK-GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256 Query: 445 AAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPG-VGVAPGVGLAPGVGV 503 + G AA A+ G PG PG VG A G G G Sbjct: 257 RGLPGERGRTGPAGAAGAR------------GNDGQPGPAGPPGPVGPAGGPGFPGAPGA 304 Query: 504 APGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLG 563 G G GP G S A +G PG G+PG Sbjct: 305 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA-----------SGNPGTD---GIPGAK 350 Query: 564 VGAGVPGLGVGAGVPGFGAVPGALAAAK--AAKYGAAVPGVLGGLGALGGVGIPGGVVGA 621 AG PG+ G PG PG A K PG+ G G G G PG A Sbjct: 351 GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP---A 407 Query: 622 GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAG 681 GP A A K GA G G GVG +G PG G G G G Sbjct: 408 GPQGAPGPAGEEGKR------GARGEPG-GVGPIGPPGERGAPG-------NRGFPGQDG 453 Query: 682 LGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG 720 L G G G+ G+A G P PG L A G Sbjct: 454 LAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 492 Score = 107 bits (267), Expect = 4e-23 Identities = 149/455 (32%), Positives = 167/455 (36%), Gaps = 54/455 (11%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P P G GA G G V PG A GA G G+ P P G AG G Sbjct: 721 PIGPPGPAGA--NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ--- 775 Query: 83 PAVTFPGALVPGGVA----DAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVK 137 PGA G A DA A +GA G G GV G + GA P PGA Sbjct: 776 -----PGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-PGATGF 829 Query: 138 PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFG 196 PG VG PG PG PG G P GA PG AG PG+ GP G Sbjct: 830 PGAAGRVGPPGSNGNPGPPGP--PGPSGKDG-PKGARGDSGPPGR----AGEPGLQGPAG 882 Query: 197 GP----QPGVPLGYPIKAPKLPGGY-------GLPYTTGKLPYGYGPGGVAGAAGKAGYP 245 P +PG + P P G GLP G+ + G G +G GK G P Sbjct: 883 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFP-GLPGPSGEPGKQGAP 941 Query: 246 TGTG-------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV 298 +G VGP A + + GA G G AGV G G +G Sbjct: 942 GASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAP 1001 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPG-- 356 G P + A K G A P GP G G+ G P AG P G Sbjct: 1002 GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLK 1061 Query: 357 --AGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG-FGV--- 409 G G +PG P A+ A G R G G P+ GA G PG G Sbjct: 1062 GHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVG-PSGKDGANGIPGPIGPPGP 1120 Query: 410 -GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 G G G AG PG G PG G PG GI A A Sbjct: 1121 RGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFA 1155 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 182 bits (462), Expect = 9e-46 Identities = 244/828 (29%), Positives = 307/828 (37%), Gaps = 164/828 (19%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPG--GVPGAI----PGGVPGGVFYPGA---------- 46 G+T A PG HP PG G PG++ G PGGV +PG+ Sbjct: 553 GMTGRAGSPG------RDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPP 606 Query: 47 GLGALGG----------------GALGPGGKPLK--PVPGGLAGAGLGAGLGAFPAVT-- 86 G G G G GP G+P K P+PG GL G FP Sbjct: 607 GYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPG-FPGPQGD 665 Query: 87 --FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGV 144 FPG PG + G G G PG G+ G + P PG +PG Sbjct: 666 RGFPGT--PGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGP-PGTPGRPGFNGLP 722 Query: 145 GLPGVY-----PGGVLPGARFPGVGVLPGVPTGAGVK-----PKAPGVGGAFA--GIPGV 192 G PGV PG LPG + G+ LPG+P G K P PG GA G+ G+ Sbjct: 723 GNPGVQGQKGEPGVGLPGLK--GLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGI 780 Query: 193 ----GPFGGP----QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY 244 GP G P PGVP P A PGG G P +G P G+ G G G+ Sbjct: 781 RGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSG-------PPGIKGEKGFPGF 833 Query: 245 PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVGTPAA 303 P GP+ A +G G LPG GA G+PG PG+ +G + G P + Sbjct: 834 PGLDMPGPKGDKGAQGLPGITGQSGLPG-LPGQQGAPGIPGFPGSKGEMGVMGTPGQPGS 892 Query: 304 AAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGVGVPGAGIPVVPGA----- 357 A + G GP PG+ G G G+P G PG+ V G+ Sbjct: 893 PGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLP--GKPGSMDKVDMGSMKGQK 950 Query: 358 ------------------GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 399 G PG PGV + A + + G + G+ G P Sbjct: 951 GDQGEKGQIGPIGEKGSRGDPG--TPGVPGKDG---QAGQPGQPGPKGDPGISGTP---- 1001 Query: 400 GAGGFPG-----FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGV 454 GA G PG G+G+ G PG GVPG+ G G G+PG + +A G+ Sbjct: 1002 GAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPG----DKGAKGEKGQAGPPGI 1057 Query: 455 GTPAAAAAKAAAKAAQFGLVPG-------VGVAPGVGVAPGVGVAPG-VGL--APGVGVA 504 G P K A F PG +G+ PG+ +PG+ +PG VG +PG+ Sbjct: 1058 GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGI-PGMPGSPGLKGSPGSVGYPGSPGLPGE 1116 Query: 505 PGVGVAPGVGVAPGI----------GPGGVAA--AAKSAAKVAAKAQLRAAAGL-GAGIP 551 G PG+ PG+ GP G A + + A + GL G G P Sbjct: 1117 KGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFP 1176 Query: 552 GLGVGVGVPGLGVGAGVPGLGVGAGVP------GFGAVPGALA-AAKAAKYGAAVPGVLG 604 G G G G PGL G+P GF PG G A G G Sbjct: 1177 GFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKG 1236 Query: 605 GLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGG 662 G G G+PG GP G GA G+ G G G+PG+GG Sbjct: 1237 DRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGG 1296 Query: 663 LGGI--------PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 GI PP G GL G+ G G + G PG Sbjct: 1297 SPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPG 1344 Score = 161 bits (408), Expect = 2e-39 Identities = 224/709 (31%), Positives = 266/709 (37%), Gaps = 129/709 (18%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTF 87 G PG P G+PG V PG G G G G P P GL+G G FP F Sbjct: 782 GEPG--PPGLPGSVGSPGVP----GIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPG--F 833 Query: 88 PGALVPGGVADAAAAYKAAKAGA-------GLGGVPGVGGLGVSAG--AVVPQPGAGVKP 138 PG +PG D A G G G PG+ G S G V+ PG P Sbjct: 834 PGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSP 893 Query: 139 GKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVG----GAFAGIPG-- 191 G V GLPG PG+ P G L G G+ K + G+ G G Sbjct: 894 GPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQ 953 Query: 192 -----VGPFGGP----QPGVPLGYPIK-----APKLPGGYGLPYTTGK--LPYGYGPGGV 235 +GP G PG P G P K P PG G P +G P GP G Sbjct: 954 GEKGQIGPIGEKGSRGDPGTP-GVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGS 1012 Query: 236 AGAAGKAGYPTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPG 291 G G G P GV GPQ + AK G AG PG+G +PG+ G G Sbjct: 1013 VGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGP-PGIG---IPGLRGE-KG 1067 Query: 292 IGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGF--GPGVVGVPGA-GVPGV--- 344 GIAG G+P K K +PG PG PG VG PG+ G+PG Sbjct: 1068 DQGIAGFPGSPGE--------KGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGD 1119 Query: 345 -GVPGA-GIPVVPG-AGIPGAAVPGVVSP-----EAAAKAAAKAAKYGARPGVGVGGIPT 396 G+PG GIP V G AG+PG PG P E + +A PG+ G P Sbjct: 1120 KGLPGLDGIPGVKGEAGLPGT--PGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPG 1177 Query: 397 YGVGAG--------GFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAK 448 + G GFPG G GIPG G G G PG G PG+ SP A K Sbjct: 1178 FPGAKGDKGSKGEVGFPGLA-GSPGIPGSKGEQGFMGPPGPQGQPGLPGSP-GHATEGPK 1235 Query: 449 AAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVG 508 + G P +PG+ G PG APGV PG PG Sbjct: 1236 GDRGPQGQPGLPGLPGPMGPPG---LPGIDGVKGDKGNPGWPGAPGV---PGPKGDPGFQ 1289 Query: 509 VAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGV 568 PG+G +PGI +K + G+PG G+PGL G+ Sbjct: 1290 GMPGIGGSPGI--------------TGSKGDMGPP-----GVPGFQGPKGLPGL---QGI 1327 Query: 569 PGLGVGAGVPGFGAVPGALAAA---KAAKYGAAVPGVLGGLGALGGVGIPG--------G 617 G GVPG +PG K +PG G G G G+PG G Sbjct: 1328 KGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTG 1387 Query: 618 VVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 665 +VG GP A + + G G G G G PG GL G Sbjct: 1388 LVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFP----GPPGPDGLPG 1432 Score = 153 bits (387), Expect = 5e-37 Identities = 235/809 (29%), Positives = 291/809 (35%), Gaps = 161/809 (19%) Query: 24 SRPGGVPGAIPGGVPGGVFYPG-----AGLGALGGGALGPGGKPLKPVPGGLAGAGLGAG 78 S P GVPG G G G G +G G+P KP P G G G Sbjct: 237 SGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKG 296 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGV----GGLGVSAGAVVP-QPG 133 P FPG G+ + K AG G PG+ G LG P PG Sbjct: 297 EKGSPG--FPGEPGYPGLIGRQGP-QGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPG 353 Query: 134 AGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK-------PKAPGVGGAF 186 +PG GLPG PG PG PG PG P G K PG G Sbjct: 354 PRGEPGPKGFPGLPG-QPGP--PGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGR- 409 Query: 187 AGIPGVGPFGGP--QPGVPLGYPIKAPKLPGGYGLPYTTGKLPY---------------- 228 G+PG GP QPG G P PG G P G+ + Sbjct: 410 DGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLI 469 Query: 229 ----GY-GPGGVAGAAGKAGYPTGTGV----------------GPQAAAAAAAKAAAKFG 267 GY GP G G G+ G+P G GPQ + AK Sbjct: 470 CDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGE 529 Query: 268 AGAAGV-LPGVGGAGVPGVPGAIPGIGGIAGV-------GTPAAAAAAAAAAKAAKYGAA 319 G L G G PG PG PG+ G AG G P + + + G Sbjct: 530 PGEFYFDLRLKGDKGDPGFPGQ-PGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPP 588 Query: 320 AGL----------VPGGPGFGP-------GVVGVPGA----GVPGV-GVPGAGIPVV--P 355 G+ PG PG+GP G G PG G+PG G PG +P+ P Sbjct: 589 GGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPP 648 Query: 356 GA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGI 414 GA G+PG+ PG P+ + G G G P G+G G PG GV G+ Sbjct: 649 GAEGLPGS--PGFPGPQGDRGFPGTPGRPGLPGEKGAVGQP--GIGFPGPPG-PKGVDGL 703 Query: 415 PGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLV 474 PG G PG G PG G+PG +P Q + + GVG P + Sbjct: 704 PGDMGPPGTPGRPGFNGLPG---NPGVQG----QKGEPGVGLPGLKGLPG---------L 747 Query: 475 PGVGVAPG----VGVAPGV-----GVAP----GVGLAPGVGVAPGVGVAPGVGVAPGIGP 521 PG+ PG +GV PGV + P G+ PG PG +PGV PGIGP Sbjct: 748 PGIPGTPGEKGSIGV-PGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGV---PGIGP 803 Query: 522 GGVAA--AAKSAAKVAAKAQLRAAAGLGAGIPGLGV--------GVGVPGLGVGAGVPGL 571 G + ++ ++ G G PGL + G+PG+ +G+PGL Sbjct: 804 PGARGPPGGQGPPGLSGPPGIKGEKGF-PGFPGLDMPGPKGDKGAQGLPGITGQSGLPGL 862 Query: 572 GVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAG-PAAAAAAA 630 G PG PG+ K PG G G +G G+PG G P ++ Sbjct: 863 PGQQGAPGIPGFPGS----KGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRG 918 Query: 631 KAAAKA--AQFGLVGAAG------LGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGL 682 K GL G G +G + G G G G G P G G+ Sbjct: 919 DPGLKGDKGDVGLPGKPGSMDKVDMGSMK-GQKGDQGEKGQIG-PIGEKGSRGDPGTPGV 976 Query: 683 GGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 G G AGQ G PG +P PG Sbjct: 977 PGKDGQAGQPGQPGPKGDPGISGTPGAPG 1005 Score = 152 bits (383), Expect = 1e-36 Identities = 237/815 (29%), Positives = 282/815 (34%), Gaps = 164/815 (20%) Query: 22 HPSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPL---KPVPGGLAGAGLG 76 +P PG +PG IPG G PG PG G LGP G P P P GL G Sbjct: 101 YPGNPG-LPG-IPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGD 158 Query: 77 AG--LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--- 131 G LG P + G + G+ G PG GL G V P Sbjct: 159 PGEILGHVPGMLLKGE----------------RGFPGIPGTPGPPGLPGLQGPVGPPGFT 202 Query: 132 --PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP-------GV 182 PG PG G G+ G GV PGVP A V+ K G Sbjct: 203 GPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQ 262 Query: 183 GG--AFAGIPGVGPFGGPQPGVPLGYPIK--------APKLPGGYGLPYTTGKLPYGYGP 232 G F G+PGVG G P P G P K +P PG G P G+ GP Sbjct: 263 KGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGR----QGP 318 Query: 233 GGVAGAAGKAGYP---TGTGV-------------GPQAAAAAAAKAAAKFGAGAAGVLPG 276 G G AG G P GTG GP+ G G LP Sbjct: 319 QGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPG-LPV 377 Query: 277 VGGAGVPGVPG-------------AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLV 323 G AG PG PG ++PG G G+ P + G G+V Sbjct: 378 PGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQP-----GYTNGIV 432 Query: 324 ---PGGPGFG--PGVVGVPG-----------------------AGVPGV-GVPGA-GIPV 353 PG PG PG+ G PG G PG G PG G P Sbjct: 433 ECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPG 492 Query: 354 VPGA----GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 408 PGA G+PG V GV P+ + GA+ G G G PGF Sbjct: 493 QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQP---GAKGEPGEFYFDLRLKGDKGDPGFP 549 Query: 409 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 468 G G+ G AG PG G PG+ G G SP + + GVG P + Sbjct: 550 -GQPGMTGRAGSPGRDGHPGLPGPKG---SPGSVGLKGERGPPGGVGFPGSRGDTGPPGP 605 Query: 469 AQFGLVPGVGVAPGVGV--APGVGVAPGVGLAPGVGVA-PGVGVAPGVGVAPGI-GPGGV 524 +G +G G PG PG PG V PG A G+ +PG GP G Sbjct: 606 PGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGD 665 Query: 525 AAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVP 584 + + + A G G PG GV GL G PG G PGF +P Sbjct: 666 RGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGT---PGRPGFNGLP 722 Query: 585 G-------------ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAK 631 G L K +PG G G++G G+PG GP Sbjct: 723 GNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRG 782 Query: 632 AAAKAAQFGLVGAAGLGGLGV-------GGLGVPGVGGLGGIP--------PAAAAKAAK 676 G VG+ G+ G+G GG G PG+ G GI P K Sbjct: 783 EPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPK 842 Query: 677 YGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 G G G+ G GQ L G+ + G P FPG Sbjct: 843 -GDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPG 876 Score = 118 bits (296), Expect = 2e-26 Identities = 148/462 (32%), Positives = 186/462 (40%), Gaps = 86/462 (18%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALG--PGGKPLKPVPGGLAGAGLGAG 78 P +PG P PG G PG PG G++GG L PG K + +PG GL Sbjct: 986 PGQPG--PKGDPGISGTPGAPGLPGPK-GSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGD 1042 Query: 79 LGAFPA---VTFPGALVPG--------GVAD--AAAAYKAAKAGAGLGGVPGVGGLGVSA 125 GA PG +PG G+A + K K G+ G+PG GL S Sbjct: 1043 KGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSP 1102 Query: 126 GAVVPQPGAGVKPGK-----VPGV-GLPGVYPGGVLPGARFP-------GVGVLPGVPTG 172 G+V PG+ PG+ +PG+ G+PGV LPG P G G+P Sbjct: 1103 GSV-GYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGS 1161 Query: 173 AGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGP 232 AG K + G F G PG G + V P L G G+P + G+ + GP Sbjct: 1162 AGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGF------PGLAGSPGIPGSKGEQGF-MGP 1214 Query: 233 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGV--LPGVGGA----GVPGVP 286 G G G G P GP+ + G G LPG+ G G PG P Sbjct: 1215 PGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWP 1274 Query: 287 GAIPGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GV 341 GA PG+ G G G P + G PG PGF G G+PG G+ Sbjct: 1275 GA-PGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP-----PGVPGF-QGPKGLPGLQGI 1327 Query: 342 PG----VGVPGA-GIPVVPGAGIPGAAV---PGVVSPEAAAKAAAKAAKYGARPGV-GVG 392 G GVPGA G+P PG P + PG+ PE PG+ G+ Sbjct: 1328 KGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGP-------------PGLKGLQ 1374 Query: 393 GIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG 434 G+P G G G G+ GIPG G+PG G PG G G Sbjct: 1375 GLP----GPKGQQGV-TGLVGIPGPPGIPGFDGAPGQKGEMG 1411 Score = 92.0 bits (227), Expect = 2e-18 Identities = 177/636 (27%), Positives = 206/636 (32%), Gaps = 163/636 (25%) Query: 211 PKLPGGYGLPYTTGKLPYG-YGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGA 268 P L G G P G P G GP G G G+ G P G GP Sbjct: 54 PGLQGVIGFPGMQG--PEGPQGPPGQKGDTGEPGLPGTKGTRGPP--------------- 96 Query: 269 GAAGVLPGVGGAGVPGVPG--------AIPGIGGIAG----VGTPAAAAAA------AAA 310 GA+G G G+PG+PG IPG G G +G P A Sbjct: 97 GASGY---PGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLP 153 Query: 311 AKAAKYGAAAGLVPG----GPGFGPGVVGVPG-AGVPG----VGVPG-AGIPVVPG-AGI 359 G G VPG G PG+ G PG G+PG VG PG G P PG G Sbjct: 154 GMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGP 213 Query: 360 PG------------------------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP 395 PG VPG + A K K G + G G+P Sbjct: 214 PGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEK-GQKGEPGFQGMP 272 Query: 396 TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GI----SPEAQAAAAAKAA 450 GVG G PG G G PG G G G PG G PG G+ P+ + A Sbjct: 273 --GVGEKGEPG-KPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPG 329 Query: 451 KYGV-------------GTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGV-- 495 G+ G P + F +PG PG+ V PG APG Sbjct: 330 PPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPV-PGQAGAPGFPG 388 Query: 496 ----------------------GLAPGVGVAPGVGVAPG-----VGVAPG----IGPGGV 524 GL PG +PG PG V PG GP G+ Sbjct: 389 ERGEKGDRGFPGTSLPGPSGRDGL-PGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGI 447 Query: 525 AAAAKSAAKVAAKAQ------------LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLG 572 ++ K Q R G G PG G PG G+PG Sbjct: 448 PGQPGFIGEIGEKGQKGESCLICDIDGYRGPPG-PQGPPGEIGFPGQPGAKGDRGLPGRD 506 Query: 573 VGAGVPGFGAVPGALAAAKA------------AKYGAAVPGVLGGLGALGGVGIPGGVVG 620 AGVPG PG + A K PG G G G G PG Sbjct: 507 GVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGH 566 Query: 621 AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY--- 677 G + + + G G G G G G PG G G P A + Sbjct: 567 PGLPGPKGSPGSVGLKGERGPPGGVGFPG-SRGDTGPPGPPGYGPAGPIGDKGQAGFPGG 625 Query: 678 -GAAGLGGVLGGAGQF-PLGGVAARPGFGLSPIFPG 711 G+ GL G G G+ PL G G SP FPG Sbjct: 626 PGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPG 661 Score = 86.7 bits (213), Expect = 7e-17 Identities = 113/368 (30%), Positives = 138/368 (37%), Gaps = 72/368 (19%) Query: 28 GVPGAIPG--GVPGGVFYPGA----------GLGALGG--------------GALGPGGK 61 G+PG+ PG G PG V YPG+ GL L G G GP G+ Sbjct: 1091 GMPGS-PGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQ 1149 Query: 62 PLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL 121 +P G+ G+ G P FPG PG D + K GL G PG+ G Sbjct: 1150 KGEPGSDGIPGSAGEKGEPGLPGRGFPG--FPGAKGDKGS--KGEVGFPGLAGSPGIPGS 1205 Query: 122 GVSAGAVVP-----QPGAGVKPGKVP----GVGLPGVYPGGVLPGARFPGVGVLPGVPTG 172 G + P QPG PG G P PG LPG PG PG+P Sbjct: 1206 KGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPG--LPG--LPGPMGPPGLPGI 1261 Query: 173 AGVK--------PKAPGVGG-----AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGL 219 GVK P APGV G F G+PG+G G P P G GL Sbjct: 1262 DGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGL 1321 Query: 220 PYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVG 278 P G G+ G G G P G+ GP + G PG+ Sbjct: 1322 P----------GLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLK 1371 Query: 279 GA-GVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGV 336 G G+PG G G+ G+ G+ G P A + + G A P G PG G+ Sbjct: 1372 GLQGLPGPKGQ-QGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGL 1430 Query: 337 PGA-GVPG 343 PG+ G PG Sbjct: 1431 PGSMGPPG 1438 Score = 72.4 bits (176), Expect = 1e-12 Identities = 91/314 (28%), Positives = 113/314 (35%), Gaps = 26/314 (8%) Query: 402 GGFPGFGVG---VGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPA 458 GG G G G G+ G G G+ G+ GV G PG+ Q K G P Sbjct: 29 GGCAGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPG 88 Query: 459 AAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAP 517 + A+ + PG+ PG PG PG+ G G PG+ G A Sbjct: 89 TKGTRGPPGASGYPGNPGLPGIPGQDGPPG---PPGIPGCNGTKGERGPLGPPGLPGFAG 145 Query: 518 GIGPGGVAAAAKSAAKVAAKAQ---LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVG 574 GP G+ ++ L+ G GIPG G+PGL G PG Sbjct: 146 NPGPPGLPGMKGDPGEILGHVPGMLLKGERGF-PGIPGTPGPPGLPGLQGPVGPPGFTGP 204 Query: 575 AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAA 634 G PG PG + + G + G G G G G PG G A A Sbjct: 205 PGPPGPPGPPG-----EKGQMGLSFQGPKGDKGDQGVSGPPG---VPGQAQVQEKGDFAT 256 Query: 635 KAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGIPPAAAAKAAK-----YGAAGLGGVLGG 688 K + G G G G+ GVG G PG G G P K K G G G++G Sbjct: 257 KGEK-GQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGR 315 Query: 689 AGQFPLGGVAARPG 702 G G A PG Sbjct: 316 QGPQGEKGEAGPPG 329 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 181 bits (460), Expect = 2e-45 Identities = 231/735 (31%), Positives = 268/735 (36%), Gaps = 102/735 (13%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 P G PG P G PG +PG+ G GP G+P + P G G Sbjct: 175 PAGPPG--PPGPPGTSGHPGSPGSP---GYQGPPGEPGQAGPSGPPGP------------ 217 Query: 86 TFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAG--AVVPQPGAGVKPGKV 141 PGA+ P G A D + GL G PG+ G G + G + G+ Sbjct: 218 --PGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEK 275 Query: 142 PGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 200 G PG+ LPG PG G P G +P PG GA G G P P Sbjct: 276 GETGAPGLKGENGLPGENGAPGPMGPRGAPGERG-RPGLPGAAGARGNDGARGSDGQPGP 334 Query: 201 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAA 259 P PG G P + G G G AG+ G G P G GPQ A A Sbjct: 335 PGP----------PGTAGFPGSPG----AKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQ 380 Query: 260 AKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 319 G+ G +G AG+PG PG + G G A A + K GA Sbjct: 381 GPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAK 440 Query: 320 AGLVPGGPGFGPGVVGVPGA----------GVPGV-GVPGA----GIPVVPGA----GIP 360 P G G+ GVPGA G PG G+PGA G P G GIP Sbjct: 441 GEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIP 500 Query: 361 GAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPG--FGVGVG 412 G P G P AA + + G G G+ G+P G G+ G PG G Sbjct: 501 GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES 560 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFG 472 G PG G G G PGV G PG + A + G G P K Q Sbjct: 561 GRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPG-PQGPPGKNGETGPQGP 619 Query: 473 LVP-GVGVAPGVGVAP---GVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAA 528 P G G G P G+ PG G PG PG G APG PGG A Sbjct: 620 PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPG-APGGKGDAG 678 Query: 529 KSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG---AGVPGLGVGAGVPGFGAVPG 585 R GL AG PGL G G PG G AG PG AG PG +PG Sbjct: 679 APGE--------RGPPGL-AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPG 729 Query: 586 ALAAAKAAKYGAAVPGVLGGLGALGGV---GIPGGVVGAGPAAAAAAAKAAAKAAQFGLV 642 + G PG G G GG G+PG GP A + G Sbjct: 730 -------ERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEG 782 Query: 643 GAAGLGGLGVGGLGVPGVGGLGGIP-----PAAAAKAAKYGAAGLGGVLGGAGQFPLGGV 697 GA GL G+ G G PG G G P P A + + G G G G G+ GV Sbjct: 783 GAPGLPGI-AGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGV 841 Query: 698 AARPGFGLSPIFPGG 712 A PG G P P G Sbjct: 842 AGPPG-GSGPAGPPG 855 Score = 171 bits (432), Expect = 3e-42 Identities = 243/768 (31%), Positives = 273/768 (35%), Gaps = 112/768 (14%) Query: 23 PSRPGGVPGAI----PGGVPGGVFYPG-AGLGALGG--GALGPGGKPLKPVPGGLAGAGL 75 PS P G PGAI P G G PG G L G G GP G P PG G Sbjct: 211 PSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIP--GFPGMKGHRGF 268 Query: 76 GAGLGAFPAVTFPGALVPGGV-----ADAAAAYKAAKAGAGLGGVPGVGGLGVSAGA--V 128 G PG G+ A + A G G+PG G + GA Sbjct: 269 DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGS 328 Query: 129 VPQPGAGVKPGKVPGVGLPG----VYPGGVLPGARFPGVGVLPGVPTGAGVK--PKAPGV 182 QPG PG G PG V P G PG PG AG + P PG+ Sbjct: 329 DGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGI 388 Query: 183 GGA--------FAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPG 233 G+ AGIPG G G P P G AP L GG G P G G Sbjct: 389 NGSPGGKGEMGPAGIPGAPGLMGARGPPGPAG-ANGAPGLRGGAGEPGKNG----AKGEP 443 Query: 234 GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV-----PGA 288 G G G+AG P G A K + GA G+ G G PG P Sbjct: 444 GPRGERGEAGIP-----GVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG 498 Query: 289 IPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA-GVPGV 344 IPG G AG G P A AA + + G VPGGPG PG G PG+ G P Sbjct: 499 IPGEKGPAGERGAPGPAGPRGAAGEPGRDG-----VPGGPGMRGMPGSPGGPGSDGKP-- 551 Query: 345 GVPG----AGIPVVPGAGIPGA--AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG 398 G PG +G P PG P V G P+ A K + G G G G P Sbjct: 552 GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKN 611 Query: 399 -----------VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAA 447 G GG G G G G+ G+PG GG PG G PG P + A A Sbjct: 612 GETGPQGPPGPTGPGGDKG-DTGPPGPQGLQGLPGTGGPPGENGKPG---EPGPKGDAGA 667 Query: 448 KAAKYGVGTPAAAAAK-----AAAKAAQFGLVP-----GVGVA-----PGVGVAPGVGVA 492 A G G A + A A + G P G G A PG PG+ Sbjct: 668 PGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGM 727 Query: 493 PGV--GL-APGVGVAPGVGVAPGVGVAPG----IGPGGVAAAAKSAAKVAAKAQLRAAAG 545 PG GL +PG G PG PG GP G A + K + G Sbjct: 728 PGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE-----G 782 Query: 546 LGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--AAKAAKYGAAVPGVL 603 G+PG+ G PG G PG G PG PG A K PGV Sbjct: 783 GAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVA 842 Query: 604 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGL 663 G G G G PG G + AA GL G G G G G G G Sbjct: 843 GPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNG-NPGPPGPSGSPGK 901 Query: 664 GGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 G PP A G+ G+ G G AGQ G PG P PG Sbjct: 902 DG-PPGPAGNTGAPGSPGVSGPKGDAGQ---PGEKGSPGAQGPPGAPG 945 Score = 162 bits (409), Expect = 1e-39 Identities = 220/703 (31%), Positives = 257/703 (36%), Gaps = 113/703 (16%) Query: 26 PGGVPGAI-PGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGLGA 81 P G PG PGG G PG GL L G G G GKP +P P G AGA Sbjct: 616 PQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGA-------- 667 Query: 82 FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK--PG 139 PGA PGG DA A + GL G PG+ G AG P+ G G PG Sbjct: 668 ------PGA--PGGKGDAGAP--GERGPPGLAGAPGLRG---GAGPPGPEGGKGAAGPPG 714 Query: 140 KVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFGGP 198 G PG+ +PG R G+G PG P G +P PG G +PG GP G Sbjct: 715 PPGAAGTPGLQG---MPGER-GGLGS-PG-PKGDKGEPGGPGADG----VPGKDGPRG-- 762 Query: 199 QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAA 258 P P+G P A + PG G G LP GP G G G+ G P GP A Sbjct: 763 -PTGPIGPPGPAGQ-PGDKGEGGAPG-LPGIAGPRGSPGERGETGPP-----GPAGFPGA 814 Query: 259 AAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGA 318 + G G G G G PGV G PG G AG P + Sbjct: 815 PGQNGEPGGKGERGAPGEKGEGGPPGVAGP-PGGSGPAGPPGPQGVKGERGS-------- 865 Query: 319 AAGLVPGGPGFG--PGVVGVPGA-------GVPGV-GVPGAGIPVVPGAGIPGAAVPGVV 368 PGGPG PG G+PG G PG G PG P P PGV Sbjct: 866 -----PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVS 920 Query: 369 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 428 P+ A + GA+ G G P G G G G G+ G G+PG G PG Sbjct: 921 GPKGDAGQPGEKGSPGAQ---GPPGAP----GPLGIAGI-TGARGLAGPPGMPGPRGSPG 972 Query: 429 VGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPG 488 GV G P A + + G P A PG PG PG Sbjct: 973 PQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE---------PGRDGNPGSDGLPG 1023 Query: 489 VGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG 547 +PG G +PG APG PG +GP G + + + A A AG Sbjct: 1024 RDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAG-KSGDRGESGPAGPAGAPGPAG-S 1081 Query: 548 AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLG 607 G PG G G G G+ G PG PG+ PG G G Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGS-------------PGPAGQQG 1128 Query: 608 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGG 665 A+G G G GP+ + G G G G G G PG G G Sbjct: 1129 AIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPG 1188 Query: 666 IPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPI 708 P A GAA + G+ G GG A P +G P+ Sbjct: 1189 PPGAPGPCCGGVGAAAIAGI----GGEKAGGFA--PYYGDEPM 1225 Score = 159 bits (401), Expect = 1e-38 Identities = 247/815 (30%), Positives = 282/815 (34%), Gaps = 178/815 (21%) Query: 17 LLSILHPSRPGGVPGAIPGGVPGGVFYPG----------------AGLGALGG--GALGP 58 L+ P P G GA G+ GG PG AG+ + G G G Sbjct: 409 LMGARGPPGPAGANGA--PGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGK 466 Query: 59 GGKPLKPVPGGLAGAGLGAGLGAFPAVT----FPGALVPGGV--ADAAAAYKAAKAGAGL 112 G P +P GL GA G F PG P G A A + A G Sbjct: 467 DGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGR 526 Query: 113 GGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGV----GLPGVYPGGVLPGARFPGVGVLPG 168 GVPG G+ G+ PG+ KPG PG G PG PG P + PGV PG Sbjct: 527 DGVPGGPGMRGMPGSP-GGPGSDGKPGP-PGSQGESGRPGP-PGPSGPRGQ-PGVMGFPG 582 Query: 169 VPTGAGVKPKAPGVGGAFAGIPGVGPFG--------GPQ-PGVPLGY-----------PI 208 G APG G G G GP G GPQ P P G P Sbjct: 583 PKGNDG----APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQ 638 Query: 209 KAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFG 267 LPG G P GK P GP G AGA G G G G + A + G Sbjct: 639 GLQGLPGTGGPPGENGK-PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG 697 Query: 268 AGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-------------GTPAAAAAAAAAAK 312 AG G G G AG PG PGA PG+ G+ G G P A K Sbjct: 698 AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757 Query: 313 AAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV-------------GVPG-AGIPVVPGA 357 G + P GP PG G GA G+PG+ G PG AG P PG Sbjct: 758 DGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQ 817 Query: 358 ----------GIPG----AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGG 403 G PG PGV P + A G + G G G GA G Sbjct: 818 NGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG----GPGAAG 873 Query: 404 FPGF--------------------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 FPG G G PG AG G G PGV G G P + Sbjct: 874 FPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG 933 Query: 444 AAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGV 503 + A+ G P A A G+ A G+ PG+ PG +PG Sbjct: 934 SPGAQ------GPPGAPGPLGIA---------GITGARGLAGPPGM---PGPRGSPGPQG 975 Query: 504 APGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL 562 G PG G++ GP G L AG AG PG G GL Sbjct: 976 VKGESGKPGANGLSGERGPPGPQG-------------LPGLAGT-AGEPGRDGNPGSDGL 1021 Query: 563 GVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG--GVGIPGGVVG 620 G PG G G G PG A A PG +G G G G P G G Sbjct: 1022 PGRDGSPG---GKGDRGENGSPG----APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAG 1074 Query: 621 A-GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAA--KY 677 A GPA + A G G G G+ G G PG G G P A + A Sbjct: 1075 APGPAGSRGAPGPQGPRGDKGETGERGAAGI-KGHRGFPGNPGAPGSPGPAGQQGAIGSP 1133 Query: 678 GAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGG 712 G AG G +G +G G + PG PI P G Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGHPG----PIGPPG 1164 Score = 138 bits (347), Expect = 2e-32 Identities = 192/629 (30%), Positives = 227/629 (36%), Gaps = 88/629 (13%) Query: 132 PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGA--------GVKPKAPGVG 183 PG PG+ G+PG PG PG+ P G+ PTG K+ Sbjct: 111 PGPPGIPGRNGDPGIPG-QPGS--PGSPGPP-GICESCPTGPQNYSPQYDSYDVKSGVAV 166 Query: 184 GAFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL--------PYGYGPGG 234 G AG PG GP G P P G+P +P PG G P G+ P GP G Sbjct: 167 GGLAGYPGPAGPPGPPGPPGTSGHP-GSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSG 225 Query: 235 VAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGV-GGAGVPGVPGAIPGIG 293 AG G++G P G G G PG+ G AG+PG PG G Sbjct: 226 PAGKDGESGRPGRPG-----------------ERGLPGP-PGIKGPAGIPGFPGMKGHRG 267 Query: 294 GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV----GVPGA 349 G A + G P GP PG G P G+PG G GA Sbjct: 268 FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRP--GLPGAAGARGNDGA 325 Query: 350 ----GIPVVPG----AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG 400 G P PG AG PG+ G V P A + + A PG P G Sbjct: 326 RGSDGQPGPPGPPGTAGFPGSPGAKGEVGP-AGSPGSNGAPGQRGEPG------PQGHAG 378 Query: 401 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAA 460 A G PG G+ G PG G G G+PG G+ G P A A + G G P Sbjct: 379 AQGPPG-PPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKN 437 Query: 461 AAKA----AAKAAQFGL--VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVG 514 AK + + G+ VPG G +PG A G+ A G APG G Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPN 497 Query: 515 VAPG-IGPGGVAAAAKSAA-KVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLG 572 PG GP G A A + AA R G G+ G+ G PG G PG Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQ 557 Query: 573 VGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKA 632 +G PG P + + PG G GA G G GG G GP Sbjct: 558 GESGRPG----PPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613 Query: 633 AAKAAQFGLVGAAG----LGGLGVGGL-GVPGVGGLGGIPPAAAAKAAK---YGAAGLGG 684 G G G G G GL G+PG GG PP K + G AG G Sbjct: 614 TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGG----PPGENGKPGEPGPKGDAGAPG 669 Query: 685 VLGGAGQFPLGGVAARPGFGLSPIFPGGA 713 GG G G PG +P GGA Sbjct: 670 APGGKGDAGAPGERGPPGLAGAPGLRGGA 698 Score = 127 bits (319), Expect = 4e-29 Identities = 164/543 (30%), Positives = 191/543 (35%), Gaps = 91/543 (16%) Query: 198 PQPGVPLG-------YPIKAPKLP-------GGYGLPYTTGKLPYGYGPGGVAGAAGKAG 243 P P +P G P AP P G G P G +P G G+ G G G Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPG-IPGRNGDPGIPGQPGSPG 133 Query: 244 YPTGTGV------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG 297 P G+ GPQ + K G G+ G AG PG PG PG G Sbjct: 134 SPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP-PGTSG--- 189 Query: 298 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA 357 PG PG PG G PG PG P + Sbjct: 190 -------------------------HPGSPG-SPGYQGPPGE--PGQAGP---------S 212 Query: 358 GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV-GVGGIPTYGVGAG--GFPGF--GVGVG 412 G PG PG + P A ++ + G RPG G+ G P AG GFPG G Sbjct: 213 GPPGP--PGAIGPSGPAGKDGESGRPG-RPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD 269 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFG 472 G G G G G+ G G+PG +P A + G P AA A+ A Sbjct: 270 GRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSD 329 Query: 473 LVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAA 532 PG PG PG +PG G +PG APG P GP G A A Sbjct: 330 GQPGPPGPPGTAGFPG---SPGAKGEVGPAGSPGSNGAPGQRGEP--GPQGHAGAQGPPG 384 Query: 533 KVAAKAQLRAAAGLG----AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA 588 +G G PGL G PG G PGL GAG PG G Sbjct: 385 PPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE-P 443 Query: 589 AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLG 648 + + A +PGV G G G G P G GA AA + A G G AG Sbjct: 444 GPRGERGEAGIPGVPGAKGEDGKDGSP-GEPGANGLPGAAGERGAP-----GFRGPAGPN 497 Query: 649 GLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPI 708 G+ G G G G P A + A G G GV GG G + G PG P Sbjct: 498 GIP----GEKGPAGERGAPGPAGPRGAA-GEPGRDGVPGGPGMRGMPGSPGGPGSDGKPG 552 Query: 709 FPG 711 PG Sbjct: 553 PPG 555 Score = 101 bits (252), Expect = 2e-21 Identities = 149/505 (29%), Positives = 169/505 (33%), Gaps = 96/505 (19%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P GG+ P G G PGA G GP G P P G G G Sbjct: 728 PGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGL 787 Query: 83 PAVTFP-------GALVPGGVAD--AAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPG 133 P + P G P G A A G G G PG G G G P G Sbjct: 788 PGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGG 847 Query: 134 AGVKPGKVPGV-GLPGVY--PGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGI 189 +G P PG G+ G PGG PGA FPG LPG P G+ P PG G+ Sbjct: 848 SG--PAGPPGPQGVKGERGSPGG--PGAAGFPGARGLPG-PPGSNGNPGPPGPSGSPGKD 902 Query: 190 PGVGPFGGPQPGVPLGYPIKAPK----LPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAG 243 GP G G P + PK PG G P G P G G+ GA G AG Sbjct: 903 GPPGPAGNT--GAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAG 960 Query: 244 YPTGTGV----GPQAAAAAAAKAAAKFGAGAAGV-----LPGVGGA-------------G 281 P G GPQ + K A +G G LPG+ G G Sbjct: 961 PPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDG 1020 Query: 282 VPGVPGAIPGIGGIAGVGTPAAAAAAA------AAAKAAKYGAAAGLVPGGPGFGPGVVG 335 +PG G+ G G G+P A A A K G P GP PG G Sbjct: 1021 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080 Query: 336 VPGAGVP--------------GVGVPG-AGIPVVPGA-GIPGAA-------VPGVVSPEA 372 GA P G+ G G P PGA G PG A PG P Sbjct: 1081 SRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRG 1140 Query: 373 AAKAAAKAAKYGARPGVGVGGIP--------TYGVGAGGFPGF----------GVGVGGI 414 + K G G G P G+ G PG G GG+ Sbjct: 1141 PVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGV 1200 Query: 415 PGVAGVPGVGGVPGVGGVPGVGISP 439 G A + G+GG G P G P Sbjct: 1201 -GAAAIAGIGGEKAGGFAPYYGDEP 1224 Score = 99.8 bits (247), Expect = 8e-21 Identities = 137/470 (29%), Positives = 166/470 (35%), Gaps = 104/470 (22%) Query: 321 GLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA-GIPGAAVPGVVS--PEAAAKAA 377 G P GP PG G+PG G PG IP PG+ G PG PG+ P + Sbjct: 101 GQGPQGPKGDPGPPGIPGRN----GDPG--IPGQPGSPGSPGP--PGICESCPTGPQNYS 152 Query: 378 AKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGI 437 + Y + GV VGG+ G PG AG PG G PG G PG Sbjct: 153 PQYDSYDVKSGVAVGGL-----------------AGYPGPAGPPGPPGPPGTSGHPGSPG 195 Query: 438 SPEAQAAAAAKAAKYGVGTP----AAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAP 493 SP Q G P A + A K + G PG G+ PG+ Sbjct: 196 SPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGR-PGRPGERGLPGPPGIKGPA 254 Query: 494 GVGLAPGV---------------GVAPGV---GVAPGVGVAPG-IGP-GGVAAAAKSAAK 533 G+ PG+ APG+ PG APG +GP G + Sbjct: 255 GIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLP 314 Query: 534 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG-------- 585 AA A+ A G PG G G G G AG PG PG Sbjct: 315 GAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQ 374 Query: 586 ALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA----GPAAAAAAAKAAAKAAQF 639 A A+ + G GG G +G GIPG G++GA GPA A A A + Sbjct: 375 GHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEP 434 Query: 640 GLVGAAG-------LGGLGVGGL----------GVPGVGGLGGIPPAAAAK--------- 673 G GA G G G+ G+ G PG G G+P AA + Sbjct: 435 GKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPA 494 Query: 674 -----------AAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGG 712 A + GA G G G AG+ GV PG P PGG Sbjct: 495 GPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGG 544 >gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo sapiens] Length = 1691 Score = 168 bits (425), Expect = 2e-41 Identities = 226/761 (29%), Positives = 288/761 (37%), Gaps = 107/761 (14%) Query: 28 GVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 G+PG +PG G PG PG GL L G PG K +PG GL G Sbjct: 602 GLPG-LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQ---QGLPGSKGITLPC 657 Query: 86 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAG-----AVVPQPGAGVKPGK 140 PG+ P G + K GL G PG G S G +V P PG Sbjct: 658 IIPGSYGPSGFP-GTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGP 716 Query: 141 VPGVGLPGVYPGGVLPGAR-FPGVGVLPGVP-----TGA--GVKPKAPGVGG-------- 184 GLPG +PG LPG PG+ PG+P TG G + APG G Sbjct: 717 RGEKGLPG-FPG--LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHK 773 Query: 185 ---AFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 +G+PG+ G G P P G +P PG G P T G GP G+ G +G Sbjct: 774 GFLGDSGLPGLKGVHGKPGLLGPKGER-GSPGTPGQVGQPGTPGSS----GPYGIKGKSG 828 Query: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-G 299 G P G+ + K + G G + G G+ G+PG PG+ G+ G G Sbjct: 829 LPGAPGFPGI-----SGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGN-PGLVGLKGSPG 882 Query: 300 TPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG----VGVPG-AG 350 +P A A + + G+ G V G PG PG+ G+PG G+PG +G G AG Sbjct: 883 SPGVAGLPALSGPKGEKGSV-GFV-GFPGI-PGLPGIPGTRGLKGIPGSTGKMGPSGRAG 939 Query: 351 IPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP-------------T 396 P G G PG G+ SP G++ G G P Sbjct: 940 TPGEKGDRGNPGPV--GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGP 997 Query: 397 YGV-GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVG 455 G+ GA G PG GV G PG G G+ G+PG+ G G+ P + ++ + G Sbjct: 998 PGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPG 1057 Query: 456 TPAAAAAKAA----AKAAQFGLVPGVGVAPGVGVAPGV----GVAPGVGLAPGVGVAPGV 507 P A+ + + PG PG G G+ +G G V Sbjct: 1058 LPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKV 1117 Query: 508 GVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA----------GIPGLGVGV 557 GV+ VG+ G GVA + A LG+ G PGL Sbjct: 1118 GVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLN 1177 Query: 558 GVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG 617 G+PG G PG + GVPG +PG G PG G G G G PG Sbjct: 1178 GLPGTKGTHGTPGPSI-TGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGL 1236 Query: 618 VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLG---------GI 666 AG A + + A Q G G GL G G G PG G G Sbjct: 1237 QGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGF 1296 Query: 667 PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSP 707 P K K G G+ G G G+ L G+ PGF +P Sbjct: 1297 PGIPGPKGPK-GDQGIPGFSGLPGELGLKGMRGEPGFMGTP 1336 Score = 153 bits (387), Expect = 5e-37 Identities = 228/792 (28%), Positives = 301/792 (38%), Gaps = 176/792 (22%) Query: 23 PSRPG--GVPGAI-----PG--GVPGGVF-----YPGA-GLGALGG--GALGPGGKP-LK 64 P PG G+PG I PG G G +F PG GL L G G LG G P LK Sbjct: 726 PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 785 Query: 65 PVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVS 124 V G GL G + PG + G ++ Y K +GL G PG G+ Sbjct: 786 GVHGK---PGLLGPKGERGSPGTPGQVGQPGTPGSSGPY-GIKGKSGLPGAPGFPGISGH 841 Query: 125 AGAVVPQ-----PGAGVKPGKVPGV-GLPGVYPGGV-LPGARFPGVGVLPGVPTGAGVKP 177 G + PG+ VK G +PG+ GLPG PG V L G+ PG + G+P +G K Sbjct: 842 PGKKGTRGKKGPPGSIVKKG-LPGLKGLPG-NPGLVGLKGS--PGSPGVAGLPALSGPKG 897 Query: 178 KAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG 237 + VG F G PG+ PG+P P G G+P +TGK+ GP G AG Sbjct: 898 EKGSVG--FVGFPGI-------PGLP-----GIPGTRGLKGIPGSTGKM----GPSGRAG 939 Query: 238 AAGKAG---YPTGTGV----------------GPQAAAAAAAKAAAKFGAGAAGVLPGVG 278 G+ G P G+ G Q +A + + G AG G Sbjct: 940 TPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPG 999 Query: 279 GAGVPGVPGAIPGIGGIAGV-------GTPAAAAAAAAAAKAAKYGAAAGL-VPGGPGFG 330 G PG+PG I G+ G G G P ++ G + + G PG Sbjct: 1000 LPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGL- 1058 Query: 331 PGVVGVPG-----------AGVPG----------------------VGVPG-----AGIP 352 PG G+PG +G PG +G PG + Sbjct: 1059 PGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVG 1118 Query: 353 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF-GV- 409 V G+PGA PGV + GA +G G+ +G GFPGF G+ Sbjct: 1119 VSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGL----IGPKGFPGFPGLH 1174 Query: 410 GVGGIPGVAGV-----PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKA 464 G+ G+PG G P + GVPG G+PG P+ + G+G P + Sbjct: 1175 GLNGLPGTKGTHGTPGPSITGVPGPAGLPG----PKGEKGYPG----IGIGAPGKPGLRG 1226 Query: 465 AAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGG 523 F PG+ G+ APG+ + + PG PG+ G PG GP G Sbjct: 1227 QKGDRGF---PGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERG---RPGPAGPPG 1280 Query: 524 VAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPG-LGVGA--GVPGF 580 + + GIPG G G+ +G+PG LG+ G PGF Sbjct: 1281 PPGPSSNQGDTGDPGF--------PGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGF 1332 Query: 581 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 640 PG + + PG+ G G G G+ G P A G Sbjct: 1333 MGTPGKVGPPGDPGF----PGMKGKAGPRGSSGLQGD-----PGQTPTAEAVQVPPGPLG 1383 Query: 641 LVGAAGLGGL-----GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLG 695 L G G+ GL G +G+ G GL GIP K G +GL G G G L Sbjct: 1384 LPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIP-------GKDGPSGLPGPPGALGDPGLP 1436 Query: 696 GVAARPGFGLSP 707 G+ PGF +P Sbjct: 1437 GLQGPPGFEGAP 1448 Score = 144 bits (363), Expect = 3e-34 Identities = 227/800 (28%), Positives = 295/800 (36%), Gaps = 156/800 (19%) Query: 20 ILHPSRPGGVPGAI-PGGVPGGVFYPG----------AGLGALGG-------GALGPGGK 61 I P G PGA+ P G PG PG GLG G G GP G Sbjct: 182 ITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGP 241 Query: 62 P-------LKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGG 114 P P G G+ G FP ++ P PG K K G+ G Sbjct: 242 PPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGP----PGFPGLGTTGEKGEKGEKGIPG 297 Query: 115 VPGVGGLGVSAGAVVPQPGAGVKPGKV--PG-------------VGLPGV-----YPGGV 154 +PG G S G P PG K G + PG +GLPG G V Sbjct: 298 LPGPRGPMGSEGVQGP-PGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAV 356 Query: 155 LPG-ARFPGVGVLPGVPTGAGVKP-KAP-GVGG--AFAGIPG-VGPFGGP----QPGVPL 204 + G PGV LPG+ G++ + P GV G A +G+PG +GP G P G P Sbjct: 357 ISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG 416 Query: 205 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG-----------KAGYPTGTG-VGP 252 I A LPG GLP GP G G ++G+P G GP Sbjct: 417 RTTIGAAGLPGRDGLP----------GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGP 466 Query: 253 QA-AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAA 310 + K + F A GV P G G PG PG G+ G+ G+ G + A Sbjct: 467 KGNLGLKGIKGDSGFCACDGGV-PNTGPPGEPGPPGPW-GLIGLPGLKGARGDRGSGGAQ 524 Query: 311 AKAAKYGAAAGLVPGGPGFGPG------VVGVPG----AGVPG----VGVPGA-GIPVVP 355 A G L P GP G + G+PG +G G +G PG G+P +P Sbjct: 525 GPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLP 584 Query: 356 G-AGIPGAAVPGVVSPEAAAKAAAKAAKYG--ARPGVGVGGIPTYGVGAGGFPGFGVGVG 412 G G+PG G + + G PG G+ G+P G G PG G Sbjct: 585 GLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLP----GPRGLPG-DKGKD 639 Query: 413 GIPGVAGVPGVGG------VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAA 466 G+PG G+PG G +PG G G +P ++ G P ++ +K Sbjct: 640 GLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEP 699 Query: 467 KAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAA 526 + +P + PG G+ PG+ PG PG+ +PG+ + G G + Sbjct: 700 GSPGLVHLPELPGFPGPRGEKGLPGFPGL---PGKDGLPGMIGSPGLPGSKG-ATGDIFG 755 Query: 527 AAKSAAKVAAKAQLRAAAGL--GAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVP 584 A A L G +G+PGL G PGL G G G PG P Sbjct: 756 AENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGL---LGPKGERGSPGTPGQVGQP 812 Query: 585 GALAAA-------KAAKYGA----AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA 633 G ++ K+ GA + G G G G G PG +V G Sbjct: 813 GTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNP 872 Query: 634 AKAAQFGLVGAAGLGGL-----------GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGL 682 G G+ G+ GL VG +G PG+ GL GIP G GL Sbjct: 873 GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIP----------GTRGL 922 Query: 683 GGVLGGAGQFPLGGVAARPG 702 G+ G G+ G A PG Sbjct: 923 KGIPGSTGKMGPSGRAGTPG 942 Score = 134 bits (336), Expect = 4e-31 Identities = 205/668 (30%), Positives = 244/668 (36%), Gaps = 129/668 (19%) Query: 2 AGLTAAAPRPGVLLLLLSILHPSRPG-----GVPGAI-PGGVPGGVFYPG-AGLGALGGG 54 +GL A PG+ HP + G G PG+I G+PG PG GL L G Sbjct: 827 SGLPGAPGFPGISG------HPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGS 880 Query: 55 ALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT-FPGALVPGGVADAAAAYKAAKAG-AGL 112 PG L P G G G FP + PG +PG K G +G Sbjct: 881 PGSPGVAGL-PALSGPKGEKGSVGFVGFPGIPGLPG--IPGTRGLKGIPGSTGKMGPSGR 937 Query: 113 GGVPGVGGLGVSAGAV-VPQP----------GAGVKPGKVPGVGLPGVYPGGVLPGARFP 161 G PG G + G V +P P G G G PG P G A P Sbjct: 938 AGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG--PRGDKGEAGRP 995 Query: 162 GVGVLPGVPTGAGV------KPKAPGVGGAFAGIPGV----GPFGGP-QPGVPLGYPIK- 209 G LPG P G+ KP PG G G+PG+ G G P PG I+ Sbjct: 996 GPPGLPGAPGLPGIIKGVSGKPGPPGFMG-IRGLPGLKGSSGITGFPGMPGESGSQGIRG 1054 Query: 210 APKLPGGYGLPYTTGKL-----------PYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAA 257 +P LPG GLP G P G G G G G+ G G Sbjct: 1055 SPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGED 1114 Query: 258 AAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKY 316 + G A PGV G G PG+PG+ G I +G+P + Sbjct: 1115 GKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLH 1174 Query: 317 GAAAGLVPGGPGF----GPGVVGVPG-AGVPGV----GVPGAGI--PVVPG--------- 356 G +PG G GP + GVPG AG+PG G PG GI P PG Sbjct: 1175 GLNG--LPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRG 1232 Query: 357 -------AGIPGAAVPGVVSPEAAAKAAAKAAKYG-----ARPG-VGVGGIP--TYGVGA 401 AG+PGA PG+ P A + G RPG G G P + G Sbjct: 1233 FPGLQGPAGLPGA--PGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGD 1290 Query: 402 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG-VGISP-EAQAAAAAKAAKYGV-GTPA 458 G PGF GIPG G G G+PG G+PG +G+ + K G G P Sbjct: 1291 TGDPGFP----GIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPG 1346 Query: 459 AAAAKA-AAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 517 K A GL G P A V V PG PG+ PG+ PG Sbjct: 1347 FPGMKGKAGPRGSSGLQGDPGQTP---TAEAVQVPPGPLGLPGIDGIPGLTGDPGAQ--- 1400 Query: 518 GIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGV 577 GP G L+ + GL GIPG G+PG G PGL G Sbjct: 1401 --GPVG----------------LQGSKGL-PGIPGKDGPSGLPGPPGALGDPGLPGLQGP 1441 Query: 578 PGFGAVPG 585 PGF PG Sbjct: 1442 PGFEGAPG 1449 Score = 131 bits (329), Expect = 3e-30 Identities = 220/817 (26%), Positives = 296/817 (36%), Gaps = 188/817 (23%) Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG 113 G GP G P G G+ +GL FPG L P G K K G+ Sbjct: 50 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERG--FPGLLGPYGP-------KGDKGPMGVP 100 Query: 114 GVPGVGGLGVSAGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPT 171 G G+ G+ G P+ PG G VG PG P G +PG+ PG+P Sbjct: 101 GFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG--PDG------YPGLLGPPGLPG 152 Query: 172 GAGVK----------------PKAPGVGG-----AFAGIPG-VGPFGGP----QPGVP-- 203 G K P PG+ G G PG VGP G P PG P Sbjct: 153 QKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGP 212 Query: 204 ------LGYPIKAPK-------LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV 250 +G + K LPG G P +TG+L + P G G+ G+ G G+ Sbjct: 213 LGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGI 272 Query: 251 GPQAAAAAAAKAAAKFGAGAAGV--LPG----VGGAGVPGVPG--------AIPGIGGIA 296 K G G+ LPG +G GV G PG PG+ G Sbjct: 273 SGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQ 332 Query: 297 GVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-------------AGVPG 343 G+ A ++ G PG PGV G+PG +GVPG Sbjct: 333 GIEGQKGDIGLPGPDVFIDIDGA--VISGNPG-DPGVPGLPGLKGDEGIQGLRGPSGVPG 389 Query: 344 V----GVPGA----GIPVVPG------------AGIPG-------AAVPGVVSPEAAAKA 376 + GVPGA G P + G AG+PG PG SPE + Sbjct: 390 LPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETET 449 Query: 377 --------AAKAAKYGARPGVGV-------------GGIPTYG-VGAGGFPG-FG-VGVG 412 + G + +G+ GG+P G G G PG +G +G+ Sbjct: 450 LHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLP 509 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQ-- 470 G+ G G G GG G G PG+ + P + K + + T +Q Sbjct: 510 GLKGARGDRGSGGAQGPAGAPGL-VGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGF 568 Query: 471 FGLV--PGVGVAPGVGVAPGVGVAPGVGL--------APGVGVAPGVGVAPGVGVAPGI- 519 G++ PG PG+ PG+ G G PG PG PG G+ PG+ Sbjct: 569 RGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGL-PGLP 627 Query: 520 GPGGVAAAAKSAAKVAAKAQLRAAAG--LGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGV 577 GP G+ K + + L + G L IPG G PG G PG G+ Sbjct: 628 GPRGL-PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT---PGFPGPKGSRGL 683 Query: 578 PGFGAVPGALAA-----AKAAKYGAAVPGVLGGLGALGGVGIPG--------GVVGAGPA 624 PG PG+ + + + +PG G G G G PG G++G+ Sbjct: 684 PGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGL 743 Query: 625 AAAAAAKAAAKAAQFGLVGAAGLGGLG-----VGGLGVPGVGGLGGIPPAAAAKAAK--- 676 + A A+ G G GL GL +G G+PG+ G+ G P K + Sbjct: 744 PGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSP 803 Query: 677 --YGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 G G G G +G + + G + PG +P FPG Sbjct: 804 GTPGQVGQPGTPGSSGPYGIKGKSGLPG---APGFPG 837 Score = 130 bits (327), Expect = 4e-30 Identities = 219/752 (29%), Positives = 270/752 (35%), Gaps = 94/752 (12%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P PG G+ G P G PG +PGA A G GP G P P G G G G Sbjct: 174 PGLPGLDGITG--PQGAPG---FPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKG 228 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAGAVVPQPGAGVKPG 139 V PG P K G G PG G G+S P G + G Sbjct: 229 VKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKG 288 Query: 140 KVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKA--PGVGGAFAGIPGV-GPF 195 + G+PG LPG R P G + G P G K PG+ G F GI G G Sbjct: 289 EKGEKGIPG------LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNG-FQGIEGQKGDI 341 Query: 196 GGPQPGVPL---GYPIKA-PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV- 250 G P P V + G I P PG GLP G G G+ G +G G P +GV Sbjct: 342 GLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGD----EGIQGLRGPSGVPGLPALSGVP 397 Query: 251 ---GPQAAAAAAAKAA--AKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVGTPAAA 304 GPQ + GAAG LPG G G PG PG + + Sbjct: 398 GALGPQGFPGLKGDQGNPGRTTIGAAG-LPGRDGLPGPPGPPGPPSPEFETETLHNKESG 456 Query: 305 AAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV-GVPGA----GIPVVPGA-- 357 + K + G GF GVP G PG G PG G+P + GA Sbjct: 457 FPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARG 516 Query: 358 -----GIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF--GV 409 G G A PG+V P G G G P G PG Sbjct: 517 DRGSGGAQGPAGAPGLVGP------------LGPSGPKGKKGEPILST-IQGMPGDRGDS 563 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGIS-----PEAQAAAAAKAAKYGVGTPAAAAAKA 464 G G GV G PG GVPG+ G+PG+ P + K G P Sbjct: 564 GSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGL 623 Query: 465 AAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGL------APGVGVAPGVGVAPGVGVAPG 518 GL PG G+ G+ + G+ L + G PG PG + G Sbjct: 624 PGLPGPRGL-PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRG 682 Query: 519 I-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGV-GVPGLGVGAGVPGLGVGAG 576 + G G ++ S + + + G P G+ G PGL G+PG+ G Sbjct: 683 LPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPG 742 Query: 577 VPGF-GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVG----AGPAAAAAA 629 +PG GA A A + G+ G G LG G+PG GV G GP + Sbjct: 743 LPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGS 802 Query: 630 AKAAAKAAQFGLVGAAGLGGL-GVGGL-GVPGVGGLGGIPPAAAAKA--------AKYGA 679 + Q G G++G G+ G GL G PG G+ G P + K G Sbjct: 803 PGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGL 862 Query: 680 AGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 GL G+ G G L G PG P G Sbjct: 863 PGLKGLPGNPGLVGLKGSPGSPGVAGLPALSG 894 Score = 122 bits (305), Expect = 2e-27 Identities = 161/530 (30%), Positives = 207/530 (39%), Gaps = 94/530 (17%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT- 86 G PG P G+PG PG G G KP P G G GL +T Sbjct: 993 GRPG--PPGLPGAPGLPGIIKGVSG-----------KPGPPGFMGIRGLPGLKGSSGITG 1039 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGL 146 FPG +PG + + + G G+PG+ G + PG +PG+ G Sbjct: 1040 FPG--MPG--ESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGT 1095 Query: 147 PGVYPGGVLPGARFPG-------VGV--------LPGVPTGAGVKPKAPGVGGAFAGIPG 191 G G++ FPG VGV PG P AG++ + PG+ G+ Sbjct: 1096 KG--RDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGE-PGLPGSSGHQGA 1152 Query: 192 VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTG-------KLPYGYGPGGVAGAAGKAGY 244 +GP G P P G+P P L G GLP T G + GP G+ G G+ GY Sbjct: 1153 IGPLGSPGLIGPKGFP-GFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGY 1211 Query: 245 PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGG-AGVPGVPG-AIPGIGGIAGVGTPA 302 P G G+G A K + G G PG+ G AG+PG PG ++P + IAG P Sbjct: 1212 P-GIGIG------APGKPGLRGQKGDRG-FPGLQGPAGLPGAPGISLPSL--IAG--QPG 1259 Query: 303 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-------GVPG-AGIPV 353 + + G A P GP G G PG G+PG G+PG +G+P Sbjct: 1260 DPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPG 1319 Query: 354 VPGA----GIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 408 G G PG PG V P K G R G+ G P G Sbjct: 1320 ELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDP-------GQTPTA 1372 Query: 409 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 468 V PG G+PG+ G+PG+ G PG AQ + +K G P K Sbjct: 1373 EAVQVPPGPLGLPGIDGIPGLTGDPG------AQGPVGLQGSKGLPGIP--------GKD 1418 Query: 469 AQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 518 GL PG A G PG+ PG APG G+ PG + G Sbjct: 1419 GPSGL-PGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVG 1467 Score = 98.6 bits (244), Expect = 2e-20 Identities = 159/555 (28%), Positives = 196/555 (35%), Gaps = 102/555 (18%) Query: 193 GPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYG----YGPGGVAGAAGKAGYPT 246 GP G P P G+ L G G P G PYG GP GV G G G P Sbjct: 53 GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLG--PYGPKGDKGPMGVPGFLGINGIPG 110 Query: 247 GTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GTPA 302 G GP+ G G VG G G PG + PG+ G G G P Sbjct: 111 HPGQPGPRGPPGLD---------GCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPV 161 Query: 303 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGA--GI 359 A + K G PG PG+ G+ G G PG PGA P P G Sbjct: 162 LAPGSFKGMK------------GDPGL-PGLDGITGPQGAPGF--PGAVGPAGPPGLQGP 206 Query: 360 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGV 417 PG PG + P+ + K G + VG+ G P G F GF G G G Sbjct: 207 PGP--PGPLGPDGNMGLGFQGEK-GVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGE 263 Query: 418 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 477 G G G+ G G PG+G + E K K G P + + PG Sbjct: 264 PGPKGFPGISGPPGFPGLGTTGE-------KGEKGEKGIPGLPGPRGPMGSEGVQGPPGQ 316 Query: 478 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV---APGVGVAPGIGPGGVAAAAKSAAKV 534 G PG+ G+ G PG V G ++ G GV Sbjct: 317 QGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVP--------- 367 Query: 535 AAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAK 594 G+PGL G+ GL +GVPGL +GVPG P K + Sbjct: 368 --------------GLPGLKGDEGIQGLRGPSGVPGLPALSGVPG-ALGPQGFPGLKGDQ 412 Query: 595 YGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA-AKAAQF-GLVGAAG-LGGLG 651 G +G G G G+PG GP + + K + F GL G G G LG Sbjct: 413 -GNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLG 471 Query: 652 VGGL-----------GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGV--- 697 + G+ GVP G PP +G GL G+ G G GG Sbjct: 472 LKGIKGDSGFCACDGGVPNTG-----PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGP 526 Query: 698 AARPGFGLSPIFPGG 712 A PG + P+ P G Sbjct: 527 AGAPGL-VGPLGPSG 540 Score = 47.4 bits (111), Expect = 5e-05 Identities = 53/174 (30%), Positives = 64/174 (36%), Gaps = 17/174 (9%) Query: 549 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG----ALAAAKAAKYGAAVPGVLG 604 G G VG PG G PGL G+PG G A + K K +PG+ G Sbjct: 125 GCNGTQGAVGFPGPD---GYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDG 181 Query: 605 GLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV-GGLGVPGVGGL 663 G G G PG V AGP G +G G GV G +G+PG G Sbjct: 182 ITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAG- 240 Query: 664 GGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGK 717 PP + + G G G G+ G PG P FPG G+ Sbjct: 241 ---PPPSTGELEFMGFPK--GKKGSKGE---PGPKGFPGISGPPGFPGLGTTGE 286 >gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo sapiens] Length = 1690 Score = 168 bits (425), Expect = 2e-41 Identities = 226/761 (29%), Positives = 288/761 (37%), Gaps = 107/761 (14%) Query: 28 GVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 G+PG +PG G PG PG GL L G PG K +PG GL G Sbjct: 601 GLPG-LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQ---QGLPGSKGITLPC 656 Query: 86 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAG-----AVVPQPGAGVKPGK 140 PG+ P G + K GL G PG G S G +V P PG Sbjct: 657 IIPGSYGPSGFP-GTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGP 715 Query: 141 VPGVGLPGVYPGGVLPGAR-FPGVGVLPGVP-----TGA--GVKPKAPGVGG-------- 184 GLPG +PG LPG PG+ PG+P TG G + APG G Sbjct: 716 RGEKGLPG-FPG--LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHK 772 Query: 185 ---AFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 +G+PG+ G G P P G +P PG G P T G GP G+ G +G Sbjct: 773 GFLGDSGLPGLKGVHGKPGLLGPKGER-GSPGTPGQVGQPGTPGSS----GPYGIKGKSG 827 Query: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-G 299 G P G+ + K + G G + G G+ G+PG PG+ G+ G G Sbjct: 828 LPGAPGFPGI-----SGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGN-PGLVGLKGSPG 881 Query: 300 TPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG----VGVPG-AG 350 +P A A + + G+ G V G PG PG+ G+PG G+PG +G G AG Sbjct: 882 SPGVAGLPALSGPKGEKGSV-GFV-GFPGI-PGLPGIPGTRGLKGIPGSTGKMGPSGRAG 938 Query: 351 IPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP-------------T 396 P G G PG G+ SP G++ G G P Sbjct: 939 TPGEKGDRGNPGPV--GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGP 996 Query: 397 YGV-GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVG 455 G+ GA G PG GV G PG G G+ G+PG+ G G+ P + ++ + G Sbjct: 997 PGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPG 1056 Query: 456 TPAAAAAKAA----AKAAQFGLVPGVGVAPGVGVAPGV----GVAPGVGLAPGVGVAPGV 507 P A+ + + PG PG G G+ +G G V Sbjct: 1057 LPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKV 1116 Query: 508 GVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA----------GIPGLGVGV 557 GV+ VG+ G GVA + A LG+ G PGL Sbjct: 1117 GVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLN 1176 Query: 558 GVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG 617 G+PG G PG + GVPG +PG G PG G G G G PG Sbjct: 1177 GLPGTKGTHGTPGPSI-TGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGL 1235 Query: 618 VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLG---------GI 666 AG A + + A Q G G GL G G G PG G G Sbjct: 1236 QGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGF 1295 Query: 667 PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSP 707 P K K G G+ G G G+ L G+ PGF +P Sbjct: 1296 PGIPGPKGPK-GDQGIPGFSGLPGELGLKGMRGEPGFMGTP 1335 Score = 153 bits (387), Expect = 5e-37 Identities = 228/792 (28%), Positives = 301/792 (38%), Gaps = 176/792 (22%) Query: 23 PSRPG--GVPGAI-----PG--GVPGGVF-----YPGA-GLGALGG--GALGPGGKP-LK 64 P PG G+PG I PG G G +F PG GL L G G LG G P LK Sbjct: 725 PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 784 Query: 65 PVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVS 124 V G GL G + PG + G ++ Y K +GL G PG G+ Sbjct: 785 GVHGK---PGLLGPKGERGSPGTPGQVGQPGTPGSSGPY-GIKGKSGLPGAPGFPGISGH 840 Query: 125 AGAVVPQ-----PGAGVKPGKVPGV-GLPGVYPGGV-LPGARFPGVGVLPGVPTGAGVKP 177 G + PG+ VK G +PG+ GLPG PG V L G+ PG + G+P +G K Sbjct: 841 PGKKGTRGKKGPPGSIVKKG-LPGLKGLPG-NPGLVGLKGS--PGSPGVAGLPALSGPKG 896 Query: 178 KAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG 237 + VG F G PG+ PG+P P G G+P +TGK+ GP G AG Sbjct: 897 EKGSVG--FVGFPGI-------PGLP-----GIPGTRGLKGIPGSTGKM----GPSGRAG 938 Query: 238 AAGKAG---YPTGTGV----------------GPQAAAAAAAKAAAKFGAGAAGVLPGVG 278 G+ G P G+ G Q +A + + G AG G Sbjct: 939 TPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPG 998 Query: 279 GAGVPGVPGAIPGIGGIAGV-------GTPAAAAAAAAAAKAAKYGAAAGL-VPGGPGFG 330 G PG+PG I G+ G G G P ++ G + + G PG Sbjct: 999 LPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGL- 1057 Query: 331 PGVVGVPG-----------AGVPG----------------------VGVPG-----AGIP 352 PG G+PG +G PG +G PG + Sbjct: 1058 PGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVG 1117 Query: 353 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF-GV- 409 V G+PGA PGV + GA +G G+ +G GFPGF G+ Sbjct: 1118 VSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGL----IGPKGFPGFPGLH 1173 Query: 410 GVGGIPGVAGV-----PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKA 464 G+ G+PG G P + GVPG G+PG P+ + G+G P + Sbjct: 1174 GLNGLPGTKGTHGTPGPSITGVPGPAGLPG----PKGEKGYPG----IGIGAPGKPGLRG 1225 Query: 465 AAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGG 523 F PG+ G+ APG+ + + PG PG+ G PG GP G Sbjct: 1226 QKGDRGF---PGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERG---RPGPAGPPG 1279 Query: 524 VAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPG-LGVGA--GVPGF 580 + + GIPG G G+ +G+PG LG+ G PGF Sbjct: 1280 PPGPSSNQGDTGDPGF--------PGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGF 1331 Query: 581 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 640 PG + + PG+ G G G G+ G P A G Sbjct: 1332 MGTPGKVGPPGDPGF----PGMKGKAGPRGSSGLQGD-----PGQTPTAEAVQVPPGPLG 1382 Query: 641 LVGAAGLGGL-----GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLG 695 L G G+ GL G +G+ G GL GIP K G +GL G G G L Sbjct: 1383 LPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIP-------GKDGPSGLPGPPGALGDPGLP 1435 Query: 696 GVAARPGFGLSP 707 G+ PGF +P Sbjct: 1436 GLQGPPGFEGAP 1447 Score = 144 bits (363), Expect = 3e-34 Identities = 227/800 (28%), Positives = 295/800 (36%), Gaps = 156/800 (19%) Query: 20 ILHPSRPGGVPGAI-PGGVPGGVFYPG----------AGLGALGG-------GALGPGGK 61 I P G PGA+ P G PG PG GLG G G GP G Sbjct: 181 ITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGP 240 Query: 62 P-------LKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGG 114 P P G G+ G FP ++ P PG K K G+ G Sbjct: 241 PPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGP----PGFPGLGTTGEKGEKGEKGIPG 296 Query: 115 VPGVGGLGVSAGAVVPQPGAGVKPGKV--PG-------------VGLPGV-----YPGGV 154 +PG G S G P PG K G + PG +GLPG G V Sbjct: 297 LPGPRGPMGSEGVQGP-PGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAV 355 Query: 155 LPG-ARFPGVGVLPGVPTGAGVKP-KAP-GVGG--AFAGIPG-VGPFGGP----QPGVPL 204 + G PGV LPG+ G++ + P GV G A +G+PG +GP G P G P Sbjct: 356 ISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG 415 Query: 205 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG-----------KAGYPTGTG-VGP 252 I A LPG GLP GP G G ++G+P G GP Sbjct: 416 RTTIGAAGLPGRDGLP----------GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGP 465 Query: 253 QA-AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAA 310 + K + F A GV P G G PG PG G+ G+ G+ G + A Sbjct: 466 KGNLGLKGIKGDSGFCACDGGV-PNTGPPGEPGPPGPW-GLIGLPGLKGARGDRGSGGAQ 523 Query: 311 AKAAKYGAAAGLVPGGPGFGPG------VVGVPG----AGVPG----VGVPGA-GIPVVP 355 A G L P GP G + G+PG +G G +G PG G+P +P Sbjct: 524 GPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLP 583 Query: 356 G-AGIPGAAVPGVVSPEAAAKAAAKAAKYG--ARPGVGVGGIPTYGVGAGGFPGFGVGVG 412 G G+PG G + + G PG G+ G+P G G PG G Sbjct: 584 GLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLP----GPRGLPG-DKGKD 638 Query: 413 GIPGVAGVPGVGG------VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAA 466 G+PG G+PG G +PG G G +P ++ G P ++ +K Sbjct: 639 GLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEP 698 Query: 467 KAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAA 526 + +P + PG G+ PG+ PG PG+ +PG+ + G G + Sbjct: 699 GSPGLVHLPELPGFPGPRGEKGLPGFPGL---PGKDGLPGMIGSPGLPGSKG-ATGDIFG 754 Query: 527 AAKSAAKVAAKAQLRAAAGL--GAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVP 584 A A L G +G+PGL G PGL G G G PG P Sbjct: 755 AENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGL---LGPKGERGSPGTPGQVGQP 811 Query: 585 GALAAA-------KAAKYGA----AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA 633 G ++ K+ GA + G G G G G PG +V G Sbjct: 812 GTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNP 871 Query: 634 AKAAQFGLVGAAGLGGL-----------GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGL 682 G G+ G+ GL VG +G PG+ GL GIP G GL Sbjct: 872 GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIP----------GTRGL 921 Query: 683 GGVLGGAGQFPLGGVAARPG 702 G+ G G+ G A PG Sbjct: 922 KGIPGSTGKMGPSGRAGTPG 941 Score = 134 bits (336), Expect = 4e-31 Identities = 205/668 (30%), Positives = 244/668 (36%), Gaps = 129/668 (19%) Query: 2 AGLTAAAPRPGVLLLLLSILHPSRPG-----GVPGAI-PGGVPGGVFYPG-AGLGALGGG 54 +GL A PG+ HP + G G PG+I G+PG PG GL L G Sbjct: 826 SGLPGAPGFPGISG------HPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGS 879 Query: 55 ALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT-FPGALVPGGVADAAAAYKAAKAG-AGL 112 PG L P G G G FP + PG +PG K G +G Sbjct: 880 PGSPGVAGL-PALSGPKGEKGSVGFVGFPGIPGLPG--IPGTRGLKGIPGSTGKMGPSGR 936 Query: 113 GGVPGVGGLGVSAGAV-VPQP----------GAGVKPGKVPGVGLPGVYPGGVLPGARFP 161 G PG G + G V +P P G G G PG P G A P Sbjct: 937 AGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG--PRGDKGEAGRP 994 Query: 162 GVGVLPGVPTGAGV------KPKAPGVGGAFAGIPGV----GPFGGP-QPGVPLGYPIK- 209 G LPG P G+ KP PG G G+PG+ G G P PG I+ Sbjct: 995 GPPGLPGAPGLPGIIKGVSGKPGPPGFMG-IRGLPGLKGSSGITGFPGMPGESGSQGIRG 1053 Query: 210 APKLPGGYGLPYTTGKL-----------PYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAA 257 +P LPG GLP G P G G G G G+ G G Sbjct: 1054 SPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGED 1113 Query: 258 AAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKY 316 + G A PGV G G PG+PG+ G I +G+P + Sbjct: 1114 GKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLH 1173 Query: 317 GAAAGLVPGGPGF----GPGVVGVPG-AGVPGV----GVPGAGI--PVVPG--------- 356 G +PG G GP + GVPG AG+PG G PG GI P PG Sbjct: 1174 GLNG--LPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRG 1231 Query: 357 -------AGIPGAAVPGVVSPEAAAKAAAKAAKYG-----ARPG-VGVGGIP--TYGVGA 401 AG+PGA PG+ P A + G RPG G G P + G Sbjct: 1232 FPGLQGPAGLPGA--PGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGD 1289 Query: 402 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG-VGISP-EAQAAAAAKAAKYGV-GTPA 458 G PGF GIPG G G G+PG G+PG +G+ + K G G P Sbjct: 1290 TGDPGFP----GIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPG 1345 Query: 459 AAAAKA-AAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 517 K A GL G P A V V PG PG+ PG+ PG Sbjct: 1346 FPGMKGKAGPRGSSGLQGDPGQTP---TAEAVQVPPGPLGLPGIDGIPGLTGDPGAQ--- 1399 Query: 518 GIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGV 577 GP G L+ + GL GIPG G+PG G PGL G Sbjct: 1400 --GPVG----------------LQGSKGL-PGIPGKDGPSGLPGPPGALGDPGLPGLQGP 1440 Query: 578 PGFGAVPG 585 PGF PG Sbjct: 1441 PGFEGAPG 1448 Score = 131 bits (329), Expect = 3e-30 Identities = 220/817 (26%), Positives = 296/817 (36%), Gaps = 188/817 (23%) Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG 113 G GP G P G G+ +GL FPG L P G K K G+ Sbjct: 49 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERG--FPGLLGPYGP-------KGDKGPMGVP 99 Query: 114 GVPGVGGLGVSAGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPT 171 G G+ G+ G P+ PG G VG PG P G +PG+ PG+P Sbjct: 100 GFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG--PDG------YPGLLGPPGLPG 151 Query: 172 GAGVK----------------PKAPGVGG-----AFAGIPG-VGPFGGP----QPGVP-- 203 G K P PG+ G G PG VGP G P PG P Sbjct: 152 QKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGP 211 Query: 204 ------LGYPIKAPK-------LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV 250 +G + K LPG G P +TG+L + P G G+ G+ G G+ Sbjct: 212 LGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGI 271 Query: 251 GPQAAAAAAAKAAAKFGAGAAGV--LPG----VGGAGVPGVPG--------AIPGIGGIA 296 K G G+ LPG +G GV G PG PG+ G Sbjct: 272 SGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQ 331 Query: 297 GVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-------------AGVPG 343 G+ A ++ G PG PGV G+PG +GVPG Sbjct: 332 GIEGQKGDIGLPGPDVFIDIDGA--VISGNPG-DPGVPGLPGLKGDEGIQGLRGPSGVPG 388 Query: 344 V----GVPGA----GIPVVPG------------AGIPG-------AAVPGVVSPEAAAKA 376 + GVPGA G P + G AG+PG PG SPE + Sbjct: 389 LPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETET 448 Query: 377 --------AAKAAKYGARPGVGV-------------GGIPTYG-VGAGGFPG-FG-VGVG 412 + G + +G+ GG+P G G G PG +G +G+ Sbjct: 449 LHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLP 508 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQ-- 470 G+ G G G GG G G PG+ + P + K + + T +Q Sbjct: 509 GLKGARGDRGSGGAQGPAGAPGL-VGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGF 567 Query: 471 FGLV--PGVGVAPGVGVAPGVGVAPGVGL--------APGVGVAPGVGVAPGVGVAPGI- 519 G++ PG PG+ PG+ G G PG PG PG G+ PG+ Sbjct: 568 RGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGL-PGLP 626 Query: 520 GPGGVAAAAKSAAKVAAKAQLRAAAG--LGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGV 577 GP G+ K + + L + G L IPG G PG G PG G+ Sbjct: 627 GPRGL-PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT---PGFPGPKGSRGL 682 Query: 578 PGFGAVPGALAA-----AKAAKYGAAVPGVLGGLGALGGVGIPG--------GVVGAGPA 624 PG PG+ + + + +PG G G G G PG G++G+ Sbjct: 683 PGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGL 742 Query: 625 AAAAAAKAAAKAAQFGLVGAAGLGGLG-----VGGLGVPGVGGLGGIPPAAAAKAAK--- 676 + A A+ G G GL GL +G G+PG+ G+ G P K + Sbjct: 743 PGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSP 802 Query: 677 --YGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 G G G G +G + + G + PG +P FPG Sbjct: 803 GTPGQVGQPGTPGSSGPYGIKGKSGLPG---APGFPG 836 Score = 130 bits (327), Expect = 4e-30 Identities = 219/752 (29%), Positives = 270/752 (35%), Gaps = 94/752 (12%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P PG G+ G P G PG +PGA A G GP G P P G G G G Sbjct: 173 PGLPGLDGITG--PQGAPG---FPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKG 227 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAGAVVPQPGAGVKPG 139 V PG P K G G PG G G+S P G + G Sbjct: 228 VKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKG 287 Query: 140 KVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKA--PGVGGAFAGIPGV-GPF 195 + G+PG LPG R P G + G P G K PG+ G F GI G G Sbjct: 288 EKGEKGIPG------LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNG-FQGIEGQKGDI 340 Query: 196 GGPQPGVPL---GYPIKA-PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV- 250 G P P V + G I P PG GLP G G G+ G +G G P +GV Sbjct: 341 GLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGD----EGIQGLRGPSGVPGLPALSGVP 396 Query: 251 ---GPQAAAAAAAKAA--AKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVGTPAAA 304 GPQ + GAAG LPG G G PG PG + + Sbjct: 397 GALGPQGFPGLKGDQGNPGRTTIGAAG-LPGRDGLPGPPGPPGPPSPEFETETLHNKESG 455 Query: 305 AAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV-GVPGA----GIPVVPGA-- 357 + K + G GF GVP G PG G PG G+P + GA Sbjct: 456 FPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARG 515 Query: 358 -----GIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF--GV 409 G G A PG+V P G G G P G PG Sbjct: 516 DRGSGGAQGPAGAPGLVGP------------LGPSGPKGKKGEPILST-IQGMPGDRGDS 562 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGIS-----PEAQAAAAAKAAKYGVGTPAAAAAKA 464 G G GV G PG GVPG+ G+PG+ P + K G P Sbjct: 563 GSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGL 622 Query: 465 AAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGL------APGVGVAPGVGVAPGVGVAPG 518 GL PG G+ G+ + G+ L + G PG PG + G Sbjct: 623 PGLPGPRGL-PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRG 681 Query: 519 I-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGV-GVPGLGVGAGVPGLGVGAG 576 + G G ++ S + + + G P G+ G PGL G+PG+ G Sbjct: 682 LPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPG 741 Query: 577 VPGF-GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVG----AGPAAAAAA 629 +PG GA A A + G+ G G LG G+PG GV G GP + Sbjct: 742 LPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGS 801 Query: 630 AKAAAKAAQFGLVGAAGLGGL-GVGGL-GVPGVGGLGGIPPAAAAKA--------AKYGA 679 + Q G G++G G+ G GL G PG G+ G P + K G Sbjct: 802 PGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGL 861 Query: 680 AGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 GL G+ G G L G PG P G Sbjct: 862 PGLKGLPGNPGLVGLKGSPGSPGVAGLPALSG 893 Score = 122 bits (305), Expect = 2e-27 Identities = 161/530 (30%), Positives = 207/530 (39%), Gaps = 94/530 (17%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT- 86 G PG P G+PG PG G G KP P G G GL +T Sbjct: 992 GRPG--PPGLPGAPGLPGIIKGVSG-----------KPGPPGFMGIRGLPGLKGSSGITG 1038 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGL 146 FPG +PG + + + G G+PG+ G + PG +PG+ G Sbjct: 1039 FPG--MPG--ESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGT 1094 Query: 147 PGVYPGGVLPGARFPG-------VGV--------LPGVPTGAGVKPKAPGVGGAFAGIPG 191 G G++ FPG VGV PG P AG++ + PG+ G+ Sbjct: 1095 KG--RDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGE-PGLPGSSGHQGA 1151 Query: 192 VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTG-------KLPYGYGPGGVAGAAGKAGY 244 +GP G P P G+P P L G GLP T G + GP G+ G G+ GY Sbjct: 1152 IGPLGSPGLIGPKGFP-GFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGY 1210 Query: 245 PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGG-AGVPGVPG-AIPGIGGIAGVGTPA 302 P G G+G A K + G G PG+ G AG+PG PG ++P + IAG P Sbjct: 1211 P-GIGIG------APGKPGLRGQKGDRG-FPGLQGPAGLPGAPGISLPSL--IAG--QPG 1258 Query: 303 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-------GVPG-AGIPV 353 + + G A P GP G G PG G+PG G+PG +G+P Sbjct: 1259 DPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPG 1318 Query: 354 VPGA----GIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 408 G G PG PG V P K G R G+ G P G Sbjct: 1319 ELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDP-------GQTPTA 1371 Query: 409 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 468 V PG G+PG+ G+PG+ G PG AQ + +K G P K Sbjct: 1372 EAVQVPPGPLGLPGIDGIPGLTGDPG------AQGPVGLQGSKGLPGIP--------GKD 1417 Query: 469 AQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 518 GL PG A G PG+ PG APG G+ PG + G Sbjct: 1418 GPSGL-PGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVG 1466 Score = 98.6 bits (244), Expect = 2e-20 Identities = 159/555 (28%), Positives = 196/555 (35%), Gaps = 102/555 (18%) Query: 193 GPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYG----YGPGGVAGAAGKAGYPT 246 GP G P P G+ L G G P G PYG GP GV G G G P Sbjct: 52 GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLG--PYGPKGDKGPMGVPGFLGINGIPG 109 Query: 247 GTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GTPA 302 G GP+ G G VG G G PG + PG+ G G G P Sbjct: 110 HPGQPGPRGPPGLD---------GCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPV 160 Query: 303 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGA--GI 359 A + K G PG PG+ G+ G G PG PGA P P G Sbjct: 161 LAPGSFKGMK------------GDPGL-PGLDGITGPQGAPGF--PGAVGPAGPPGLQGP 205 Query: 360 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGV 417 PG PG + P+ + K G + VG+ G P G F GF G G G Sbjct: 206 PGP--PGPLGPDGNMGLGFQGEK-GVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGE 262 Query: 418 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 477 G G G+ G G PG+G + E K K G P + + PG Sbjct: 263 PGPKGFPGISGPPGFPGLGTTGE-------KGEKGEKGIPGLPGPRGPMGSEGVQGPPGQ 315 Query: 478 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV---APGVGVAPGIGPGGVAAAAKSAAKV 534 G PG+ G+ G PG V G ++ G GV Sbjct: 316 QGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVP--------- 366 Query: 535 AAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAK 594 G+PGL G+ GL +GVPGL +GVPG P K + Sbjct: 367 --------------GLPGLKGDEGIQGLRGPSGVPGLPALSGVPG-ALGPQGFPGLKGDQ 411 Query: 595 YGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA-AKAAQF-GLVGAAG-LGGLG 651 G +G G G G+PG GP + + K + F GL G G G LG Sbjct: 412 -GNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLG 470 Query: 652 VGGL-----------GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGV--- 697 + G+ GVP G PP +G GL G+ G G GG Sbjct: 471 LKGIKGDSGFCACDGGVPNTG-----PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGP 525 Query: 698 AARPGFGLSPIFPGG 712 A PG + P+ P G Sbjct: 526 AGAPGL-VGPLGPSG 539 Score = 47.4 bits (111), Expect = 5e-05 Identities = 53/174 (30%), Positives = 64/174 (36%), Gaps = 17/174 (9%) Query: 549 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG----ALAAAKAAKYGAAVPGVLG 604 G G VG PG G PGL G+PG G A + K K +PG+ G Sbjct: 124 GCNGTQGAVGFPGPD---GYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDG 180 Query: 605 GLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV-GGLGVPGVGGL 663 G G G PG V AGP G +G G GV G +G+PG G Sbjct: 181 ITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAG- 239 Query: 664 GGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGK 717 PP + + G G G G+ G PG P FPG G+ Sbjct: 240 ---PPPSTGELEFMGFPK--GKKGSKGE---PGPKGFPGISGPPGFPGLGTTGE 285 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 167 bits (423), Expect = 3e-41 Identities = 235/732 (32%), Positives = 282/732 (38%), Gaps = 91/732 (12%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAG-LGAFPA 84 P G+ G P G PG PG G GP G+P +P G AGA AG G Sbjct: 92 PMGLMG--PRGPPGAAGAPGPQ------GFQGPAGEPGEPGQTGPAGARGPAGPPGKAGE 143 Query: 85 VTFPGALVPGGVAD-AAAAYKAAKAGAGLGGVPGVGGLGVSAG--AVVPQPGAGVKPGKV 141 PG PG + + A+ G G+PG G+ G + QPGA Sbjct: 144 DGHPGK--PGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGA------- 194 Query: 142 PGV-GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 200 PGV G PG PG G LPG G APG GA VGP G Sbjct: 195 PGVKGEPGAPGENGTPGQ--TGARGLPGERGRVG----APGPAGARGSDGSVGPVG---- 244 Query: 201 GVPLGYPIKAPKLPGGYGLPYTTGKLPY--GYGPGGVAGAAGKAGYPTGTG-VGPQAAAA 257 P G PI + PG G P G++ GP G AG G+ G P +G VGP Sbjct: 245 --PAG-PIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPG 301 Query: 258 AAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAG-------VGTPAAAAAAAA 309 A AK GAAG LPGV GA G+PG P IPG G AG VG P A + Sbjct: 302 ANGLTGAK---GAAG-LPGVAGAPGLPG-PRGIPGPVGAAGATGARGLVGEPGPAGSKGE 356 Query: 310 AAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPGA-GIPGA-AVPG 366 + + G+A P GP G G P G PG G+ PG+ G+PGA G Sbjct: 357 SGNKGEPGSAGPQGPPGPSGEEGKRG-PNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAG 415 Query: 367 VVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--------GIPGVA 418 V+ P + A+ A G G G P +G G PG +G G+PG+ Sbjct: 416 VMGPPGSRGASGPAGVRGPNGDAGRPGEPGL-MGPRGLPGSPGNIGPAGKEGPVGLPGID 474 Query: 419 GVPGVGGVPGVGGVPG-VGI-SPEAQAAAAAKAAKYG-VGTPAAAAAK-------AAAKA 468 G PG G G G PG +G P+ K G G A A A Sbjct: 475 GRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPP 534 Query: 469 AQFGLVPGVGV-----APGVGVAPG-VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPG 522 G+ G G PG PG G A VG G+ G+ G GP Sbjct: 535 GPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPP 594 Query: 523 GVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFG 581 G + AA + ++ G G PG+ VG G +G+PG AG+PG Sbjct: 595 GESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGK 654 Query: 582 AVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGL 641 G + PG G GA G VG PG G A AA A A G Sbjct: 655 GEKG----EPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGS 710 Query: 642 VGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 701 G G G G G G G G P A + AK G G GV+G G P+G AA P Sbjct: 711 PGERGEVG-PAGPNGFAGPAGAAGQPGAKGERGAK-GPKGENGVVGPTG--PVG--AAGP 764 Query: 702 GFGLSPIFPGGA 713 P P G+ Sbjct: 765 AGPNGPPGPAGS 776 Score = 166 bits (419), Expect = 9e-41 Identities = 266/818 (32%), Positives = 302/818 (36%), Gaps = 170/818 (20%) Query: 23 PSRPGGVPGAIPGGVPG--GVF---YPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGL 75 P+ P G PG P G PG G F Y G G+G G G +GP G P G AGA Sbjct: 58 PTGPPGPPG--PPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPP------GAAGAPG 109 Query: 76 GAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAG-AGLGGVPGVGGLGVSAGAVVPQPGA 134 G PA PG PG A A A G AG G PG G G V PQ Sbjct: 110 PQGFQG-PAGE-PGE--PGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGAR 165 Query: 135 GVKPGKVPGV-GLPGVYPGGVLPGAR----FPGVGVLPGVP--------TGAGVKPK--- 178 G PG PG+ G G+ L G + PGV PG P TGA P Sbjct: 166 GF-PG-TPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERG 223 Query: 179 ---APGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY--GYGPG 233 APG GA VGP G P G PI + PG G P G++ GP Sbjct: 224 RVGAPGPAGARGSDGSVGPVG------PAG-PIGSAGPPGFPGAPGPKGEIGAVGNAGPA 276 Query: 234 GVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIP 290 G AG G+ G P +G VGP A AK GAAG LPGV GA PG+PG IP Sbjct: 277 GPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAK---GAAG-LPGVAGA--PGLPGPRGIP 330 Query: 291 GIGGIAG-------VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGF-----GP----GVV 334 G G AG VG P A + + + G+A P GP GP G Sbjct: 331 GPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSA 390 Query: 335 GVPGA----GVPGV-GVPGA----GIPVVPG----------------AGIPGAAVPGVVS 369 G PG G PG G+PGA G+ PG AG PG PG++ Sbjct: 391 GPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGE--PGLMG 448 Query: 370 PEAAAKAAAKAAKYGARPGVGVGGI-----PTYGVGAGGFPGF-----------GVGVGG 413 P + G VG+ GI P GA G PG G G Sbjct: 449 PRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNG 508 Query: 414 IPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPA-------AAAAKAAA 466 G AG+ G G PG G G P Q K + G P + A Sbjct: 509 DKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVG 568 Query: 467 KAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPG-VGVAPGVGVAPGVGVAPGIGPGGVA 525 K + GL G+ PG G PG A G G G + G G GV Sbjct: 569 KPGERGLHGEFGL-PGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVV 627 Query: 526 AAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG 585 A +A + + L G AGIPG G PGL G PG G PG PG Sbjct: 628 GAVGTAGP-SGPSGLPGERG-AAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPG 685 Query: 586 -ALAAAKAAKYGAAVP----GVLGGLGALGGVGIPGGVVGAGPAAAA----AAAKAAAKA 636 A A + GAA P G G G G VG G AGPA AA A + AK Sbjct: 686 PAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKG 745 Query: 637 AQ--------FGLVGAAG----------LGGLGVGG-------------LGVPGVGGLGG 665 + G VGAAG G G GG G PG G+ G Sbjct: 746 PKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISG 805 Query: 666 IPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF 703 PP A K G G G G G+ G PGF Sbjct: 806 -PPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGF 842 Score = 163 bits (412), Expect = 6e-40 Identities = 246/795 (30%), Positives = 284/795 (35%), Gaps = 140/795 (17%) Query: 23 PSRPG--GVPGAIPG--GVPGGVFYPGA-GLGALGGGALGPGGKPLKPVPGGLAGAGLGA 77 P PG G PGA PG G PG GA GL G PG + G + G Sbjct: 192 PGAPGVKGEPGA-PGENGTPGQT---GARGLPGERGRVGAPGPAGARGSDGSVGPVGPAG 247 Query: 78 GLGAFPAVTFPGALVPGGVADAAAAYKAAKAG-AGLGGVPGVGGLGVSAGAVVP--QPGA 134 +G+ FPGA PG + A A AG AG G G+ GL +G V P PGA Sbjct: 248 PIGSAGPPGFPGA--PGPKGEIGAVGNAGPAGPAGPRGEVGLPGL---SGPVGPPGNPGA 302 Query: 135 GVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFA-----G 188 G GLPGV LPG R PG G TGA PG G+ G Sbjct: 303 NGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGA-TGARGLVGEPGPAGSKGESGNKG 361 Query: 189 IPG-VGPFGGPQPGVPLGY-----------PIKAPKL---PGGYGLPYTTGKL----PYG 229 PG GP G P P G P P L PG GLP G+ P G Sbjct: 362 EPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPG 421 Query: 230 Y----GPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGG----- 279 GP GV G G AG P G+ GP+ + G G LPG+ G Sbjct: 422 SRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVG-LPGIDGRPGPI 480 Query: 280 --AGVPGVPGAI-----------------PGIGGIAGV-GTPAAAAAAAAAAKAAKYGAA 319 AG G PG I G G+AG G P A G Sbjct: 481 GPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQ 540 Query: 320 AGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA-GIPGAAVP-GVVSPEAAAKAA 377 G GP PG G+PG P V G + G G+PG A P G P + AA Sbjct: 541 GGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAA 600 Query: 378 AKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGI 437 G+R G G P G G G GV G G AG G G+PG G G+ Sbjct: 601 GPTGPIGSR---GPSGPP----GPDGNKG-EPGVVGAVGTAGPSGPSGLPGERGAAGI-- 650 Query: 438 SPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGV-GVAPGVG 496 P + + +G P A+ A PG APG A G G A G Sbjct: 651 -PGGKGEKGEPGLRGEIGNPGRDGARGA---------PGAVGAPGPAGATGDRGEAGAAG 700 Query: 497 LAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGV 555 A G G VG A GP G A A +A + AK + A G G+ G Sbjct: 701 PAGPAGPRGSPGERGEVGPA---GPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTG 757 Query: 556 GVGVPGLGVGAGVPGLGVG---AGVPGFGAVPGALAAA----------------KAAKYG 596 VG G G PG G PG PGA A K G Sbjct: 758 PVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEG 817 Query: 597 AAVP----GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-- 650 P G +G G +G VG PG GP+ A A GL+GA G+ GL Sbjct: 818 LRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPG 877 Query: 651 --------GVGG-LGVPGVGGLGGIP-----PAAAAKAAKYGAAGLGGVLGGAGQFPLGG 696 GV G +G PG G+ G P P A GA G G G G G Sbjct: 878 SRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPG 937 Query: 697 VAARPGFGLSPIFPG 711 +PG +PG Sbjct: 938 RDGQPGHKGERGYPG 952 Score = 162 bits (410), Expect = 1e-39 Identities = 227/719 (31%), Positives = 263/719 (36%), Gaps = 86/719 (11%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 P G PG G PG PGA A G +GP G P G+ G AG P + Sbjct: 392 PPGPPGL--RGSPGSRGLPGADGRA---GVMGPPGSRGASGPAGVRGPNGDAGRPGEPGL 446 Query: 86 TFPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGV 144 P L PG + A K G G+ G PG G + G +PG PG Sbjct: 447 MGPRGL-PGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARG----EPGNIGFPGPKGPT 501 Query: 145 GLPGVYPGGVLPGARFPGVGVLPGVP--TGAGVKPKAPGVGGAFA--GIPGVGPFGG-PQ 199 G PG G A G PG GA P GV G G PG F G P Sbjct: 502 GDPG--KNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPG 559 Query: 200 PGVPLGYPIKAPK--LPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTG------- 249 P P G K + L G +GLP G P G GP G +GAAG G P G+ Sbjct: 560 PSGPAGEVGKPGERGLHGEFGLPGPAG--PRGERGPPGESGAAGPTG-PIGSRGPSGPPG 616 Query: 250 ----------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAG 297 VG A + + GAAG+ G G G PG+ G I PG G G Sbjct: 617 PDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARG 676 Query: 298 V-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPG 356 G A A A + GAA P GP PG G G P AG PG Sbjct: 677 APGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPG 736 Query: 357 A-GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGV----GVGGIPTYGVGAGGFPGF 407 A G GA P GVV P AA A G PG G GG P G GFPG Sbjct: 737 AKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGP-PGPAGSRGDGGPP----GMTGFPG- 790 Query: 408 GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG-VGTPAAAAAKAAA 466 G G PG +G+ G G PG G G+ P + + G VG P A K + Sbjct: 791 AAGRTGPPGPSGISGPPGPPGPAGKEGLR-GPRGDQGPVGRTGEVGAVGPPGFAGEKGPS 849 Query: 467 KAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV-GVAPGVGVAPGVGVAPGIGPGGVA 525 A PG G+ APG+ PG G+ GVA VG +G+A G G Sbjct: 850 GEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPP 909 Query: 526 AAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG 585 A S G PG G PG G PG G G PG Sbjct: 910 GAVGSPGV--------------NGAPGEAGRDGNPG---NDGPPGRDGQPGHKGERGYPG 952 Query: 586 ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAA 645 + A A PG G +G G G G +GP A A + G+ G Sbjct: 953 NIGPVGA----AGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDK 1008 Query: 646 GLGGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 G G G G+PG+ G G+ P A GA G G G G G A + G Sbjct: 1009 GEPG-EKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDG 1066 Score = 144 bits (362), Expect = 4e-34 Identities = 196/651 (30%), Positives = 238/651 (36%), Gaps = 72/651 (11%) Query: 111 GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVP 170 G G PG GLG + A G G+ PG +GL G P G A PG G P Sbjct: 63 GPPGPPGPPGLGGNFAAQYDGKGVGLGPGP---MGLMG--PRGPPGAAGAPGPQGFQG-P 116 Query: 171 TGAGVKPKAPGVGGAF--AGIPG-VGPFGGP-QPGVPLGYPIKAPKLPGGYGLPYTTGKL 226 G +P G GA AG PG G G P +PG P + P+ G G P T G L Sbjct: 117 AGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQ--GARGFPGTPG-L 173 Query: 227 PYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGA----GAAGVLPGVGGAGV 282 P G G G G G P GV + A + GA G G + G AG Sbjct: 174 PGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGA 233 Query: 283 PGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVP 342 G G++ +G +G+ A + GA P GP G VG+PG P Sbjct: 234 RGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGP 293 Query: 343 GVGVPG-------------AGIPVVPGA-GIPG-AAVPGVVSPEAAAKAAAKAAKYGARP 387 VG PG AG+P V GA G+PG +PG V A A + G Sbjct: 294 -VGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAG 352 Query: 388 GVGVGGIPTYGVGAG--GFPGFG--------VGVGGIPGVAGVPGVGGVPGVGGVPGVGI 437 G G AG G PG G G G G PG+ G PG G+PG Sbjct: 353 SKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGA-- 410 Query: 438 SPEAQAAAAAKAAKYGVGTPAAAAAK--AAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGV 495 + +A G PA A + + GL+ G+ G G V Sbjct: 411 --DGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPV 468 Query: 496 GLAPGVGVAPG-VGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGL 553 GL PG+ PG +G A G IG G K K A GA G G Sbjct: 469 GL-PGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGN 527 Query: 554 GVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGA-------AVPGVLGG 605 G PG G G G PGF +PG A + K G +PG G Sbjct: 528 NGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGP 587 Query: 606 LGALGGVGIPGGVVGAGPAAAAAAAKAA---AKAAQFGLVGAAGLGGLGVGGLGVPGVGG 662 G G G G GP + + + G+VGA G G G G+PG G Sbjct: 588 RGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPS-GPSGLPGERG 646 Query: 663 LGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGA 713 GIP K G GL G +G G+ G PG +P P GA Sbjct: 647 AAGIPGGKGEK----GEPGLRGEIGNPGR---DGARGAPGAVGAP-GPAGA 689 Score = 77.0 bits (188), Expect = 6e-14 Identities = 101/330 (30%), Positives = 116/330 (35%), Gaps = 43/330 (13%) Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-GVGTPAAAAAKAAAKA 468 G G G G PG G G G PG P AA+Y G G Sbjct: 39 GPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGV------------ 86 Query: 469 AQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAA 527 GL PG G PG APG G PG G A G GP G A Sbjct: 87 ---GLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGE 143 Query: 528 AKSAAKVAAKAQLRAAAGLGA----GIPGLG--VGV----GVPGLGVGAGVPGLGVGAGV 577 K + GA G PGL G+ G+ GL G PG+ G Sbjct: 144 DGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGA 203 Query: 578 PGFGAVPGALAA----AKAAKYGAAVP-GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKA 632 PG PG A + + GA P G G G++G VG G + AGP A Sbjct: 204 PGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGP 263 Query: 633 AAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQF 692 + G G AG G G +G+PG+ G G P GA GL G G AG Sbjct: 264 KGEIGAVGNAGPAGPAGPR-GEVGLPGLSGPVGPP-------GNPGANGLTGAKGAAG-- 313 Query: 693 PLGGVAARPGFGLSPIFPGGACLGKACGRK 722 L GVA PG PG A G + Sbjct: 314 -LPGVAGAPGLPGPRGIPGPVGAAGATGAR 342 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 167 bits (422), Expect = 4e-41 Identities = 235/798 (29%), Positives = 288/798 (36%), Gaps = 178/798 (22%) Query: 24 SRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 S P G PG +PG G PG + +PG GA GP G P +PG G G Sbjct: 490 SGPPGQPG-LPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP--GIPGAPGAPGFPGSKGE 546 Query: 82 -FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK 140 +TFPG K K G G PG+ GL PG + G Sbjct: 547 PGDILTFPGM-------------KGDKGELGSPGAPGLPGL----------PGTPGQDG- 582 Query: 141 VPGVGLPGVYPGGV-LPGARFP-GVGVLPGVPTGAG-VKPKAPGVGGAFA--GIPGVGPF 195 +PG+ P PGG+ G R P G LPG+P G + P G G GI GV Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA-- 640 Query: 196 GGP-QPGVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 252 G P QPG+P G P + PG GLP G+ G G+ G G G P G+ Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGR----DGDVGLPGDPGLPGQPGLPGI-- 694 Query: 253 QAAAAAAAKAAAKFGAGAAGV-LPGVGGA-GVPGVPGAIPGIGGIAG-VGTPAAAAAAAA 309 +K G G+ LPG G G PG+PG PG G G +G Sbjct: 695 ---------PGSKGEPGIPGIGLPGPPGPKGFPGIPGP-PGAPGTPGRIGLEGPPGPPGF 744 Query: 310 AAKAAKYGAAAGLVPGGPG-------FGP----------------GVVGVPG-------- 338 + G A PG PG GP G+ G+PG Sbjct: 745 PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 339 --------AGVPGVGVPG-AGIPVVPGA-------GIPG----AAVPGVVSPEAAAKAAA 378 G+PG+GV G G P +PG GIPG PG+ P + + Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864 Query: 379 KAAKYGARPGVGVGGIPTY--GVGAGGFPGFG-----VGVGGIPGVAGVPGVGGVPGVGG 431 GA +G G P GA GFPG +G G PG G+PG GVPG+ G Sbjct: 865 PGIP-GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKG 923 Query: 432 VPGVGISPEAQAAAAAKAAKYGVGTPAAAAAK------AAAKAAQFGL--VPGVGVAPGV 483 G+ P K +K G P + + + GL +PGV G Sbjct: 924 DDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGY 983 Query: 484 GVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI------------------------ 519 PG PG+ PG+ PG PG+ PG+ Sbjct: 984 QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043 Query: 520 -GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 578 GP GV S K G+PGL G PGL G PG+ G P Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103 Query: 579 GFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI------------PGGVVGAGPAAA 626 G +PG AK +PG G G G GI PG V G G Sbjct: 1104 GLPGLPG----TPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159 Query: 627 AAAAKAAAKAAQFGLVGAAG-LGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGV 685 K Q G+ G AG G G G G PG GL G+ + + G GL G+ Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL-------SGQKGDGGLPGI 1212 Query: 686 LGGAGQFPLGGVAARPGF 703 G G L G PGF Sbjct: 1213 PGNPG---LPGPKGEPGF 1227 Score = 162 bits (410), Expect = 1e-39 Identities = 224/738 (30%), Positives = 273/738 (36%), Gaps = 106/738 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA----GLGALGG--GALGPGGKPLKPVPGGLAGAGLG 76 P P G+PG G PG PG GL + G G GP G + PG G+ Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAGAVVP----- 130 G PG +PG A+ + K G+ G PG G LG+ + VP Sbjct: 869 GAPGPIGPPGSPG--LPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 131 -----QPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG- 184 QPG G+ G PG+ PG PG P + G G+ P PGV G Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGL-PGP--PGPMDPNLLGSKGEKGEPGL-PGIPGVSGP 980 Query: 185 -AFAGIPGVG--PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGK 241 + G+PG P QPG+P G P PK G GLP G + GP G+ G G Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLP-GPP--GPK--GNPGLPGQPGLI----GPPGLKGTIGD 1031 Query: 242 AGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGAGVPGVPG--------AIP 290 G+P GV GP + + + G G PG+ G+PG+PG P Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091 Query: 291 GIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG-V 344 G GI G VG P + PG PGF PG G PG +G PG Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQ--------PGLPGF-PGTPGPPGPKGISGPPGNP 1142 Query: 345 GVPGAGIPVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG 400 G+PG PV G G PG P G + A + + G +PG G G P G Sbjct: 1143 GLPGEPGPV-GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG-QPGFGNPGPPGLP-G 1199 Query: 401 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAA 460 G G G G+ GIPG G+PG G PG G PGV P + A + G P Sbjct: 1200 LSGQKGDG-GLPGIPGNPGLPGPKGEPGFHGFPGVQ-GPPGPPGSPGPALEGPKGNPGPQ 1257 Query: 461 AAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIG 520 F +PG PG+ PG G G PG PG+ G PG+ Sbjct: 1258 GPPGRPGPTGFQGLPGPEGPPGL---PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL- 1313 Query: 521 PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 580 G + K G PGL G PG+ +GVPG G PG Sbjct: 1314 QGNPGRPGLNGMK---------------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1358 Query: 581 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 640 PG + + G G G G G+ G GP + G Sbjct: 1359 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1418 Query: 641 LVGAAGLGG-LGVGGL-GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGG---------- 688 L G G GG G GL G PG GL G PP G G V G Sbjct: 1419 LPGFDGAGGRKGDPGLPGQPGTRGLDG-PPGPDGLQGPPGPPGTSSVAHGFLITRHSQTT 1477 Query: 689 -AGQFPLGGVAARPGFGL 705 A Q P G + GF L Sbjct: 1478 DAPQCPQGTLQVYEGFSL 1495 Score = 162 bits (409), Expect = 1e-39 Identities = 226/718 (31%), Positives = 265/718 (36%), Gaps = 101/718 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGK---PLKPVPGGLAGA-GLG 76 P P G PG P G PG G L G GALGP G P P P G G GL Sbjct: 738 PPGPPGFPG--PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV 136 G PG + P G+ G G+ G PG G+ G QPG Sbjct: 796 GPKGDVGPNGQPGPMGPPGLP-----------GIGVQGPPGPPGIPGPIG----QPGLHG 840 Query: 137 KPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG---- 191 PG+ G PG+ G PG R PG+ PG P G P PG GA +G PG Sbjct: 841 IPGEKGDPGPPGLDVPGP-PGERGSPGIPGAPG-PIGPPGSPGLPGKAGA-SGFPGTKGE 897 Query: 192 VGPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 +G G P P PLG P ++ P L G GL G LP GP G G+ G+ G P Sbjct: 898 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LP---GPTGEKGSKGEPGLP---- 949 Query: 250 VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAA 308 GP G +L G G PG+PG IPG+ G G G P Sbjct: 950 -GPP-------------GPMDPNLLGSKGEKGEPGLPG-IPGVSGPKGYQGLPGDPGQPG 994 Query: 309 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVV 368 + + G P GP PG+ G PG +G PG + G PG GV Sbjct: 995 LSGQPGLPG------PPGPKGNPGLPGQPGL----IGPPGLK-GTIGDMGFPGPQ--GVE 1041 Query: 369 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 428 P + + G G G P G+ + G PG G G PG+ G PG G+ G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDP--GISSIGLPGLP-GPKGEPGLPGYPGNPGIKG 1098 Query: 429 VGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPG 488 G PG+ P A GTP K + +PG G G PG Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPG 1158 Query: 489 VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIG-PGGVAAAAKSAAKVAAKAQLRAAAGLG 547 PG PG PG G PG G PG S K G G Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQK-----------GDG 1207 Query: 548 AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP-GVLGGL 606 G+PG+ G PGL G PG GV G PG+ A G P G G Sbjct: 1208 -GLPGI---PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRP 1263 Query: 607 GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL-GGLGVGGL----GVPGVG 661 G G G+PG G Q GL G GL G G GL G PG+ Sbjct: 1264 GPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1323 Query: 662 GLGGIP--PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF----GLSPIFPGGA 713 G+ G P P G +G+ G G G+ L G PG G S I G A Sbjct: 1324 GMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDA 1381 Score = 159 bits (402), Expect = 9e-39 Identities = 225/743 (30%), Positives = 278/743 (37%), Gaps = 111/743 (14%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPG--GLAGAGLGAGLGAFPAV 85 G PGA G PG +PG G G G P +PG GL G GL P Sbjct: 386 GPPGAAVMGPPGPPGFPGER------GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439 Query: 86 TFPGALVPGGVADAAAAYKAAKAG-AGLGGVPGVGG---------LGVSAGAVVPQPGAG 135 P + + G GL G GV G +G QPG Sbjct: 440 AGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 136 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-- 192 PG +G PG GA P G+ +PG P G P + G G PG+ Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF-PGSKGEPGDILTFPGMKG 558 Query: 193 --GPFGGP-QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 G G P PG+P P PG GLP G P G PGG+ G+ G P G Sbjct: 559 DKGELGSPGAPGLP-----GLPGTPGQDGLPGLPG--PKGE-PGGIT-FKGERGPPGNPG 609 Query: 250 VGPQAAAAAAAKAAAKFGA-GAAGVLPGVGGAGVPGVPGAIPGIGGIAG--VGTPAAAAA 306 + P FG G G G AG PG PG IPG G G + P Sbjct: 610 L-PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG-IPGPKGDPGQTITQPGKPGL 667 Query: 307 AAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA----GVPGVGVPGA----GIPVVPG 356 + G +PG PG PG+ G+PG+ G+PG+G+PG G P +PG Sbjct: 668 PGNPGRDGDVG-----LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722 Query: 357 A-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--- 412 G PG PG + E G PG + G P G G PGF +G Sbjct: 723 PPGAPGT--PGRIGLEGPPGPPGFPGPKG-EPGFALPGPP----GPPGLPGFKGALGPKG 775 Query: 413 --GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQ 470 G PG G PG G+ G+ G G + P Q G+G Sbjct: 776 DRGFPGPPGPPGRTGLDGLPGPKG-DVGPNGQPGPMGPPGLPGIGVQGPPGPPG------ 828 Query: 471 FGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA--PGVGVAPGVGVAPG-IGPGGVAAA 527 +PG PG+ PG PG PG+ V PG +PG+ APG IGP G + Sbjct: 829 ---IPGPIGQPGLHGIPGEKGDPG---PPGLDVPGPPGERGSPGIPGAPGPIGPPG-SPG 881 Query: 528 AKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 587 A + + G+ G PG +G+PG +GVPGL G+ G +PG Sbjct: 882 LPGKAGASGFPGTKGEMGM-MGPPGPPGPLGIPGR---SGVPGLKGDDGLQGQPGLPGP- 936 Query: 588 AAAKAAKYGAAVPG--------VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 639 K +K +PG +LG G G G+PG +GP K Q Sbjct: 937 TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP-----------KGYQ- 984 Query: 640 GLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAA 699 GL G G GL G G+PG G G P + G GL G +G G GV Sbjct: 985 GLPGDPGQPGLS-GQPGLPGPPGPKG-NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042 Query: 700 RPGFGLSPIFPGGACLGKACGRK 722 PG P PG L G K Sbjct: 1043 PPGPSGVPGQPGSPGLPGQKGDK 1065 Score = 129 bits (325), Expect = 7e-30 Identities = 208/734 (28%), Positives = 253/734 (34%), Gaps = 139/734 (18%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 HP PG PG P G PG G G G P P P G+ G GL Sbjct: 58 HPGLPG-FPG--PEGPPGP------------RGQKGDDGIPGPPGPKGIRGP---PGLPG 99 Query: 82 FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKV 141 FP PG +PG A G G+PG G G PG+ PG Sbjct: 100 FPGT--PG--LPGMPGHDGAP--------GPQGIPGCNGTKGERGF----PGSPGFPGLQ 143 Query: 142 PGVGLPGVYPGGVLPGARF-PGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 200 G PG+ PG + PG ++ +P G P PG G G+PG P G P P Sbjct: 144 GPPGPPGI------PGMKGEPGSIIMSSLPGPKG-NPGYPGPPG-IQGLPG--PTGIPGP 193 Query: 201 GVPLGYP-IKAPKLPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAAA 258 P G P + P PG GLP G + + GP G G G G P GP + Sbjct: 194 IGPPGPPGLMGP--PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP-----GPPGQISE 246 Query: 259 AAKAA-AKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKY 316 + +F G G+ G G PG+ G GG G G K + Sbjct: 247 QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306 Query: 317 GAAAGLVPGGPGFGPGVVGVPGA-------------GVPGVGVPGAGIPVVPGA------ 357 G +PG PG PG G PG G PG+ +P G + G Sbjct: 307 GQPG--IPGLPG-DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363 Query: 358 -GIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF----- 407 G+PG PG+ P PG V G P G GFPG Sbjct: 364 PGLPGEKGERGFPGIQGPPGLP----------GPPGAAVMGPP----GPPGFPGERGQKG 409 Query: 408 -----GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG----VGTPA 458 G+ + G PG+ G PG G+PG G G I P + G G Sbjct: 410 DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469 Query: 459 AAAAKAAAKAAQFGLV-PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 517 K F + G+ PG PG+ PG PG G A G P Sbjct: 470 EQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP 529 Query: 518 GIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGV 577 GI PG A +K G PG+ G G G+PGL G Sbjct: 530 GI-PGAPGAPGFPGSK--------GEPGDILTFPGMKGDKGELGSPGAPGLPGL---PGT 577 Query: 578 PGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 637 PG +PG L K G G G G G G+PG + GP Sbjct: 578 PGQDGLPG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP-------- 628 Query: 638 QFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGV 697 G VG G+ G+ G G PG+ G G P + K G G G G G G+ Sbjct: 629 --GPVGEKGIQGV-AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGL 685 Query: 698 AARPGFGLSPIFPG 711 +PG P PG Sbjct: 686 PGQPGL---PGIPG 696 Score = 70.9 bits (172), Expect = 4e-12 Identities = 118/425 (27%), Positives = 142/425 (33%), Gaps = 84/425 (19%) Query: 291 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 349 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 350 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 409 G PG +PG PE G R G GIP G PG Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP-------GPPG--- 87 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAA 469 GI G G+PG G PG+ G+PG +P Q K G P + Sbjct: 88 -PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG-------- 138 Query: 470 QFGLVPGVGVAPGVGVAPGVGVAPG---VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAA 526 PG+ PG PG+ PG + PG PG PG+ P GP G+ Sbjct: 139 ----FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP--GPTGIPG 192 Query: 527 AAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA-----GVPGFG 581 G PGL G PGL G GL G G Sbjct: 193 PIGP-----------------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQ 235 Query: 582 AVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGL 641 PG K V G G G G PG GP K + + G Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK--GEKGEQGE 293 Query: 642 VGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 701 G G G G G PG+ GL G P + + G G G G G P G V RP Sbjct: 294 PGKRGKPGKD-GENGQPGIPGLPG-DPGYPGEPGRDGEKGQKGDTGPPG--PPGLVIPRP 349 Query: 702 GFGLS 706 G G++ Sbjct: 350 GTGIT 354 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 167 bits (422), Expect = 4e-41 Identities = 235/798 (29%), Positives = 288/798 (36%), Gaps = 178/798 (22%) Query: 24 SRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 S P G PG +PG G PG + +PG GA GP G P +PG G G Sbjct: 490 SGPPGQPG-LPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP--GIPGAPGAPGFPGSKGE 546 Query: 82 -FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK 140 +TFPG K K G G PG+ GL PG + G Sbjct: 547 PGDILTFPGM-------------KGDKGELGSPGAPGLPGL----------PGTPGQDG- 582 Query: 141 VPGVGLPGVYPGGV-LPGARFP-GVGVLPGVPTGAG-VKPKAPGVGGAFA--GIPGVGPF 195 +PG+ P PGG+ G R P G LPG+P G + P G G GI GV Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA-- 640 Query: 196 GGP-QPGVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 252 G P QPG+P G P + PG GLP G+ G G+ G G G P G+ Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGR----DGDVGLPGDPGLPGQPGLPGI-- 694 Query: 253 QAAAAAAAKAAAKFGAGAAGV-LPGVGGA-GVPGVPGAIPGIGGIAG-VGTPAAAAAAAA 309 +K G G+ LPG G G PG+PG PG G G +G Sbjct: 695 ---------PGSKGEPGIPGIGLPGPPGPKGFPGIPGP-PGAPGTPGRIGLEGPPGPPGF 744 Query: 310 AAKAAKYGAAAGLVPGGPG-------FGP----------------GVVGVPG-------- 338 + G A PG PG GP G+ G+PG Sbjct: 745 PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 339 --------AGVPGVGVPG-AGIPVVPGA-------GIPG----AAVPGVVSPEAAAKAAA 378 G+PG+GV G G P +PG GIPG PG+ P + + Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864 Query: 379 KAAKYGARPGVGVGGIPTY--GVGAGGFPGFG-----VGVGGIPGVAGVPGVGGVPGVGG 431 GA +G G P GA GFPG +G G PG G+PG GVPG+ G Sbjct: 865 PGIP-GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKG 923 Query: 432 VPGVGISPEAQAAAAAKAAKYGVGTPAAAAAK------AAAKAAQFGL--VPGVGVAPGV 483 G+ P K +K G P + + + GL +PGV G Sbjct: 924 DDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGY 983 Query: 484 GVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI------------------------ 519 PG PG+ PG+ PG PG+ PG+ Sbjct: 984 QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043 Query: 520 -GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 578 GP GV S K G+PGL G PGL G PG+ G P Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103 Query: 579 GFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI------------PGGVVGAGPAAA 626 G +PG AK +PG G G G GI PG V G G Sbjct: 1104 GLPGLPG----TPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159 Query: 627 AAAAKAAAKAAQFGLVGAAG-LGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGV 685 K Q G+ G AG G G G G PG GL G+ + + G GL G+ Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL-------SGQKGDGGLPGI 1212 Query: 686 LGGAGQFPLGGVAARPGF 703 G G L G PGF Sbjct: 1213 PGNPG---LPGPKGEPGF 1227 Score = 163 bits (413), Expect = 5e-40 Identities = 222/720 (30%), Positives = 260/720 (36%), Gaps = 111/720 (15%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGK---PLKPVPGGLAGA-GLG 76 P P G PG P G PG G L G GALGP G P P P G G GL Sbjct: 738 PPGPPGFPG--PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV 136 G PG + P G+ G G+ G PG G+ G QPG Sbjct: 796 GPKGDVGPNGQPGPMGPPGLP-----------GIGVQGPPGPPGIPGPIG----QPGLHG 840 Query: 137 KPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG---- 191 PG+ G PG+ G PG R PG+ PG P G P PG GA +G PG Sbjct: 841 IPGEKGDPGPPGLDVPGP-PGERGSPGIPGAPG-PIGPPGSPGLPGKAGA-SGFPGTKGE 897 Query: 192 VGPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 +G G P P PLG P ++ P L G GL G LP GP G G+ G+ G P Sbjct: 898 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LP---GPTGEKGSKGEPGLP---- 949 Query: 250 VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAA 308 GP G +L G G PG+PG IPG+ G G G P Sbjct: 950 -GPP-------------GPMDPNLLGSKGEKGEPGLPG-IPGVSGPKGYQGLPGDPGQPG 994 Query: 309 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVV 368 + + G P GP PG+ G PG +G PG + G PG GV Sbjct: 995 LSGQPGLPG------PPGPKGNPGLPGQPGL----IGPPGLK-GTIGDMGFPGPQ--GVE 1041 Query: 369 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 428 P + + G G G P G+ + G PG G G PG+ G PG G+ G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDP--GISSIGLPGLP-GPKGEPGLPGYPGNPGIKG 1098 Query: 429 VGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPG 488 G PG+ P A GTP K + +PG G G PG Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPG 1158 Query: 489 VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA 548 PG PG PG G PG G G Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG-----------------------PP 1195 Query: 549 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGAAVPGVLGGLG 607 G+PGL G GL G PGL G PGF PG G A+ G G G Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG 1255 Query: 608 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL----GVGGL----GVPG 659 G G PG GP + G G GL GL G GL G PG Sbjct: 1256 PQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPG 1315 Query: 660 VGGLGGIP--PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF----GLSPIFPGGA 713 + G+ G P P G +G+ G G G+ L G PG G S I G A Sbjct: 1316 LNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDA 1375 Score = 159 bits (402), Expect = 9e-39 Identities = 225/743 (30%), Positives = 278/743 (37%), Gaps = 111/743 (14%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPG--GLAGAGLGAGLGAFPAV 85 G PGA G PG +PG G G G P +PG GL G GL P Sbjct: 386 GPPGAAVMGPPGPPGFPGER------GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439 Query: 86 TFPGALVPGGVADAAAAYKAAKAG-AGLGGVPGVGG---------LGVSAGAVVPQPGAG 135 P + + G GL G GV G +G QPG Sbjct: 440 AGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 136 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-- 192 PG +G PG GA P G+ +PG P G P + G G PG+ Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF-PGSKGEPGDILTFPGMKG 558 Query: 193 --GPFGGP-QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 G G P PG+P P PG GLP G P G PGG+ G+ G P G Sbjct: 559 DKGELGSPGAPGLP-----GLPGTPGQDGLPGLPG--PKGE-PGGIT-FKGERGPPGNPG 609 Query: 250 VGPQAAAAAAAKAAAKFGA-GAAGVLPGVGGAGVPGVPGAIPGIGGIAG--VGTPAAAAA 306 + P FG G G G AG PG PG IPG G G + P Sbjct: 610 L-PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG-IPGPKGDPGQTITQPGKPGL 667 Query: 307 AAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA----GVPGVGVPGA----GIPVVPG 356 + G +PG PG PG+ G+PG+ G+PG+G+PG G P +PG Sbjct: 668 PGNPGRDGDVG-----LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722 Query: 357 A-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--- 412 G PG PG + E G PG + G P G G PGF +G Sbjct: 723 PPGAPGT--PGRIGLEGPPGPPGFPGPKG-EPGFALPGPP----GPPGLPGFKGALGPKG 775 Query: 413 --GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQ 470 G PG G PG G+ G+ G G + P Q G+G Sbjct: 776 DRGFPGPPGPPGRTGLDGLPGPKG-DVGPNGQPGPMGPPGLPGIGVQGPPGPPG------ 828 Query: 471 FGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA--PGVGVAPGVGVAPG-IGPGGVAAA 527 +PG PG+ PG PG PG+ V PG +PG+ APG IGP G + Sbjct: 829 ---IPGPIGQPGLHGIPGEKGDPG---PPGLDVPGPPGERGSPGIPGAPGPIGPPG-SPG 881 Query: 528 AKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 587 A + + G+ G PG +G+PG +GVPGL G+ G +PG Sbjct: 882 LPGKAGASGFPGTKGEMGM-MGPPGPPGPLGIPGR---SGVPGLKGDDGLQGQPGLPGP- 936 Query: 588 AAAKAAKYGAAVPG--------VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 639 K +K +PG +LG G G G+PG +GP K Q Sbjct: 937 TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP-----------KGYQ- 984 Query: 640 GLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAA 699 GL G G GL G G+PG G G P + G GL G +G G GV Sbjct: 985 GLPGDPGQPGLS-GQPGLPGPPGPKG-NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042 Query: 700 RPGFGLSPIFPGGACLGKACGRK 722 PG P PG L G K Sbjct: 1043 PPGPSGVPGQPGSPGLPGQKGDK 1065 Score = 129 bits (325), Expect = 7e-30 Identities = 208/734 (28%), Positives = 253/734 (34%), Gaps = 139/734 (18%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 HP PG PG P G PG G G G P P P G+ G GL Sbjct: 58 HPGLPG-FPG--PEGPPGP------------RGQKGDDGIPGPPGPKGIRGP---PGLPG 99 Query: 82 FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKV 141 FP PG +PG A G G+PG G G PG+ PG Sbjct: 100 FPGT--PG--LPGMPGHDGAP--------GPQGIPGCNGTKGERGF----PGSPGFPGLQ 143 Query: 142 PGVGLPGVYPGGVLPGARF-PGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 200 G PG+ PG + PG ++ +P G P PG G G+PG P G P P Sbjct: 144 GPPGPPGI------PGMKGEPGSIIMSSLPGPKG-NPGYPGPPG-IQGLPG--PTGIPGP 193 Query: 201 GVPLGYP-IKAPKLPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAAA 258 P G P + P PG GLP G + + GP G G G G P GP + Sbjct: 194 IGPPGPPGLMGP--PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP-----GPPGQISE 246 Query: 259 AAKAA-AKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKY 316 + +F G G+ G G PG+ G GG G G K + Sbjct: 247 QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306 Query: 317 GAAAGLVPGGPGFGPGVVGVPGA-------------GVPGVGVPGAGIPVVPGA------ 357 G +PG PG PG G PG G PG+ +P G + G Sbjct: 307 GQPG--IPGLPG-DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363 Query: 358 -GIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF----- 407 G+PG PG+ P PG V G P G GFPG Sbjct: 364 PGLPGEKGERGFPGIQGPPGLP----------GPPGAAVMGPP----GPPGFPGERGQKG 409 Query: 408 -----GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG----VGTPA 458 G+ + G PG+ G PG G+PG G G I P + G G Sbjct: 410 DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469 Query: 459 AAAAKAAAKAAQFGLV-PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 517 K F + G+ PG PG+ PG PG G A G P Sbjct: 470 EQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP 529 Query: 518 GIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGV 577 GI PG A +K G PG+ G G G+PGL G Sbjct: 530 GI-PGAPGAPGFPGSK--------GEPGDILTFPGMKGDKGELGSPGAPGLPGL---PGT 577 Query: 578 PGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 637 PG +PG L K G G G G G G+PG + GP Sbjct: 578 PGQDGLPG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP-------- 628 Query: 638 QFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGV 697 G VG G+ G+ G G PG+ G G P + K G G G G G G+ Sbjct: 629 --GPVGEKGIQGV-AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGL 685 Query: 698 AARPGFGLSPIFPG 711 +PG P PG Sbjct: 686 PGQPGL---PGIPG 696 Score = 70.9 bits (172), Expect = 4e-12 Identities = 118/425 (27%), Positives = 142/425 (33%), Gaps = 84/425 (19%) Query: 291 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 349 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 350 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 409 G PG +PG PE G R G GIP G PG Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP-------GPPG--- 87 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAA 469 GI G G+PG G PG+ G+PG +P Q K G P + Sbjct: 88 -PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG-------- 138 Query: 470 QFGLVPGVGVAPGVGVAPGVGVAPG---VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAA 526 PG+ PG PG+ PG + PG PG PG+ P GP G+ Sbjct: 139 ----FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP--GPTGIPG 192 Query: 527 AAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA-----GVPGFG 581 G PGL G PGL G GL G G Sbjct: 193 PIGP-----------------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQ 235 Query: 582 AVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGL 641 PG K V G G G G PG GP K + + G Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK--GEKGEQGE 293 Query: 642 VGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 701 G G G G G PG+ GL G P + + G G G G G P G V RP Sbjct: 294 PGKRGKPGKD-GENGQPGIPGLPG-DPGYPGEPGRDGEKGQKGDTGPPG--PPGLVIPRP 349 Query: 702 GFGLS 706 G G++ Sbjct: 350 GTGIT 354 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 167 bits (422), Expect = 4e-41 Identities = 235/798 (29%), Positives = 288/798 (36%), Gaps = 178/798 (22%) Query: 24 SRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 S P G PG +PG G PG + +PG GA GP G P +PG G G Sbjct: 490 SGPPGQPG-LPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP--GIPGAPGAPGFPGSKGE 546 Query: 82 -FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK 140 +TFPG K K G G PG+ GL PG + G Sbjct: 547 PGDILTFPGM-------------KGDKGELGSPGAPGLPGL----------PGTPGQDG- 582 Query: 141 VPGVGLPGVYPGGV-LPGARFP-GVGVLPGVPTGAG-VKPKAPGVGGAFA--GIPGVGPF 195 +PG+ P PGG+ G R P G LPG+P G + P G G GI GV Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA-- 640 Query: 196 GGP-QPGVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 252 G P QPG+P G P + PG GLP G+ G G+ G G G P G+ Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGR----DGDVGLPGDPGLPGQPGLPGI-- 694 Query: 253 QAAAAAAAKAAAKFGAGAAGV-LPGVGGA-GVPGVPGAIPGIGGIAG-VGTPAAAAAAAA 309 +K G G+ LPG G G PG+PG PG G G +G Sbjct: 695 ---------PGSKGEPGIPGIGLPGPPGPKGFPGIPGP-PGAPGTPGRIGLEGPPGPPGF 744 Query: 310 AAKAAKYGAAAGLVPGGPG-------FGP----------------GVVGVPG-------- 338 + G A PG PG GP G+ G+PG Sbjct: 745 PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 339 --------AGVPGVGVPG-AGIPVVPGA-------GIPG----AAVPGVVSPEAAAKAAA 378 G+PG+GV G G P +PG GIPG PG+ P + + Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864 Query: 379 KAAKYGARPGVGVGGIPTY--GVGAGGFPGFG-----VGVGGIPGVAGVPGVGGVPGVGG 431 GA +G G P GA GFPG +G G PG G+PG GVPG+ G Sbjct: 865 PGIP-GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKG 923 Query: 432 VPGVGISPEAQAAAAAKAAKYGVGTPAAAAAK------AAAKAAQFGL--VPGVGVAPGV 483 G+ P K +K G P + + + GL +PGV G Sbjct: 924 DDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGY 983 Query: 484 GVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI------------------------ 519 PG PG+ PG+ PG PG+ PG+ Sbjct: 984 QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043 Query: 520 -GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 578 GP GV S K G+PGL G PGL G PG+ G P Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103 Query: 579 GFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI------------PGGVVGAGPAAA 626 G +PG AK +PG G G G GI PG V G G Sbjct: 1104 GLPGLPG----TPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159 Query: 627 AAAAKAAAKAAQFGLVGAAG-LGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGV 685 K Q G+ G AG G G G G PG GL G+ + + G GL G+ Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL-------SGQKGDGGLPGI 1212 Query: 686 LGGAGQFPLGGVAARPGF 703 G G L G PGF Sbjct: 1213 PGNPG---LPGPKGEPGF 1227 Score = 162 bits (411), Expect = 8e-40 Identities = 218/704 (30%), Positives = 255/704 (36%), Gaps = 120/704 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGK---PLKPVPGGLAGA-GLG 76 P P G PG P G PG G L G GALGP G P P P G G GL Sbjct: 738 PPGPPGFPG--PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV 136 G PG + P G+ G G+ G PG G+ G QPG Sbjct: 796 GPKGDVGPNGQPGPMGPPGLP-----------GIGVQGPPGPPGIPGPIG----QPGLHG 840 Query: 137 KPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG---- 191 PG+ G PG+ G PG R PG+ PG P G P PG GA +G PG Sbjct: 841 IPGEKGDPGPPGLDVPGP-PGERGSPGIPGAPG-PIGPPGSPGLPGKAGA-SGFPGTKGE 897 Query: 192 VGPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 +G G P P PLG P ++ P L G GL G LP GP G G+ G+ G P Sbjct: 898 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG-LP---GPTGEKGSKGEPGLP---- 949 Query: 250 VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAA 308 GP G +L G G PG+PG IPG+ G G G P Sbjct: 950 -GPP-------------GPMDPNLLGSKGEKGEPGLPG-IPGVSGPKGYQGLPGDPGQPG 994 Query: 309 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVV 368 + + G P GP PG+ G PG +G PG + G PG GV Sbjct: 995 LSGQPGLPG------PPGPKGNPGLPGQPGL----IGPPGLK-GTIGDMGFPGPQ--GVE 1041 Query: 369 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 428 P + + G G G P G+ + G PG G G PG+ G PG G+ G Sbjct: 1042 GPPGPSGVPGQPGSPGLPGQKGDKGDP--GISSIGLPGLP-GPKGEPGLPGYPGNPGIKG 1098 Query: 429 VGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPG 488 G PG+ P A GTP K + +PG G G PG Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPG 1158 Query: 489 VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA 548 PG PG PG G PG G G Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG-----------------------PP 1195 Query: 549 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGAAVPGVLGGLG 607 G+PGL G GL G PGL G PGF PG G A+ G G G Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG 1255 Query: 608 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 667 G G PG GP G G G GG+ G G PG GL G+P Sbjct: 1256 PQGPPGRPGFQGLPGPE---------------GPPGLPGNGGI-KGEKGNPGQPGLPGLP 1299 Query: 668 PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 G G G+ G G+ L G+ PG P FPG Sbjct: 1300 -------GLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1336 Score = 160 bits (405), Expect = 4e-39 Identities = 225/739 (30%), Positives = 273/739 (36%), Gaps = 111/739 (15%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA----GLGALGG--GALGPGGKPLKPVPGGLAGAGLG 76 P P G+PG G PG PG GL + G G GP G + PG G+ Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAGAVVP----- 130 G PG +PG A+ + K G+ G PG G LG+ + VP Sbjct: 869 GAPGPIGPPGSPG--LPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 131 -----QPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG- 184 QPG G+ G PG+ PG PG P + G G+ P PGV G Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGL-PGP--PGPMDPNLLGSKGEKGEPGL-PGIPGVSGP 980 Query: 185 -AFAGIPGVG--PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGK 241 + G+PG P QPG+P G P PK G GLP G + GP G+ G G Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLP-GPP--GPK--GNPGLPGQPGLI----GPPGLKGTIGD 1031 Query: 242 AGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGAGVPGVPG--------AIP 290 G+P GV GP + + + G G PG+ G+PG+PG P Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091 Query: 291 GIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG-V 344 G GI G VG P + PG PGF PG G PG +G PG Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQ--------PGLPGF-PGTPGPPGPKGISGPPGNP 1142 Query: 345 GVPGAGIPVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG 400 G+PG PV G G PG P G + A + + G +PG G G P G Sbjct: 1143 GLPGEPGPV-GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG-QPGFGNPGPPGLP-G 1199 Query: 401 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAA 460 G G G G+ GIPG G+PG G PG G PGV P + A + G P Sbjct: 1200 LSGQKGDG-GLPGIPGNPGLPGPKGEPGFHGFPGVQ-GPPGPPGSPGPALEGPKGNPGPQ 1257 Query: 461 AAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGI 519 PG PG PG+ PG G G PG PG+ G+ Sbjct: 1258 GPPGR---------PGFQGLPGPEGPPGL---PGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1305 Query: 520 GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPG 579 GP G+ K G PGL G PG+ +GVPG G PG Sbjct: 1306 GPPGLQGNPGRPGLNGMK-----------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPG 1354 Query: 580 FGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 639 PG + + G G G G G+ G GP + Sbjct: 1355 LIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRN 1414 Query: 640 GLVGAAGLGG-LGVGGL-GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGG--------- 688 GL G G GG G GL G PG GL G PP G G V G Sbjct: 1415 GLPGFDGAGGRKGDPGLPGQPGTRGLDG-PPGPDGLQGPPGPPGTSSVAHGFLITRHSQT 1473 Query: 689 --AGQFPLGGVAARPGFGL 705 A Q P G + GF L Sbjct: 1474 TDAPQCPQGTLQVYEGFSL 1492 Score = 159 bits (402), Expect = 9e-39 Identities = 225/743 (30%), Positives = 278/743 (37%), Gaps = 111/743 (14%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPG--GLAGAGLGAGLGAFPAV 85 G PGA G PG +PG G G G P +PG GL G GL P Sbjct: 386 GPPGAAVMGPPGPPGFPGER------GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439 Query: 86 TFPGALVPGGVADAAAAYKAAKAG-AGLGGVPGVGG---------LGVSAGAVVPQPGAG 135 P + + G GL G GV G +G QPG Sbjct: 440 AGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 136 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-- 192 PG +G PG GA P G+ +PG P G P + G G PG+ Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF-PGSKGEPGDILTFPGMKG 558 Query: 193 --GPFGGP-QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 G G P PG+P P PG GLP G P G PGG+ G+ G P G Sbjct: 559 DKGELGSPGAPGLP-----GLPGTPGQDGLPGLPG--PKGE-PGGIT-FKGERGPPGNPG 609 Query: 250 VGPQAAAAAAAKAAAKFGA-GAAGVLPGVGGAGVPGVPGAIPGIGGIAG--VGTPAAAAA 306 + P FG G G G AG PG PG IPG G G + P Sbjct: 610 L-PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG-IPGPKGDPGQTITQPGKPGL 667 Query: 307 AAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA----GVPGVGVPGA----GIPVVPG 356 + G +PG PG PG+ G+PG+ G+PG+G+PG G P +PG Sbjct: 668 PGNPGRDGDVG-----LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722 Query: 357 A-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--- 412 G PG PG + E G PG + G P G G PGF +G Sbjct: 723 PPGAPGT--PGRIGLEGPPGPPGFPGPKG-EPGFALPGPP----GPPGLPGFKGALGPKG 775 Query: 413 --GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQ 470 G PG G PG G+ G+ G G + P Q G+G Sbjct: 776 DRGFPGPPGPPGRTGLDGLPGPKG-DVGPNGQPGPMGPPGLPGIGVQGPPGPPG------ 828 Query: 471 FGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA--PGVGVAPGVGVAPG-IGPGGVAAA 527 +PG PG+ PG PG PG+ V PG +PG+ APG IGP G + Sbjct: 829 ---IPGPIGQPGLHGIPGEKGDPG---PPGLDVPGPPGERGSPGIPGAPGPIGPPG-SPG 881 Query: 528 AKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 587 A + + G+ G PG +G+PG +GVPGL G+ G +PG Sbjct: 882 LPGKAGASGFPGTKGEMGM-MGPPGPPGPLGIPGR---SGVPGLKGDDGLQGQPGLPGP- 936 Query: 588 AAAKAAKYGAAVPG--------VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 639 K +K +PG +LG G G G+PG +GP K Q Sbjct: 937 TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP-----------KGYQ- 984 Query: 640 GLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAA 699 GL G G GL G G+PG G G P + G GL G +G G GV Sbjct: 985 GLPGDPGQPGLS-GQPGLPGPPGPKG-NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042 Query: 700 RPGFGLSPIFPGGACLGKACGRK 722 PG P PG L G K Sbjct: 1043 PPGPSGVPGQPGSPGLPGQKGDK 1065 Score = 129 bits (325), Expect = 7e-30 Identities = 208/734 (28%), Positives = 253/734 (34%), Gaps = 139/734 (18%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 HP PG PG P G PG G G G P P P G+ G GL Sbjct: 58 HPGLPG-FPG--PEGPPGP------------RGQKGDDGIPGPPGPKGIRGP---PGLPG 99 Query: 82 FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKV 141 FP PG +PG A G G+PG G G PG+ PG Sbjct: 100 FPGT--PG--LPGMPGHDGAP--------GPQGIPGCNGTKGERGF----PGSPGFPGLQ 143 Query: 142 PGVGLPGVYPGGVLPGARF-PGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 200 G PG+ PG + PG ++ +P G P PG G G+PG P G P P Sbjct: 144 GPPGPPGI------PGMKGEPGSIIMSSLPGPKG-NPGYPGPPG-IQGLPG--PTGIPGP 193 Query: 201 GVPLGYP-IKAPKLPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAAA 258 P G P + P PG GLP G + + GP G G G G P GP + Sbjct: 194 IGPPGPPGLMGP--PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP-----GPPGQISE 246 Query: 259 AAKAA-AKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKY 316 + +F G G+ G G PG+ G GG G G K + Sbjct: 247 QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306 Query: 317 GAAAGLVPGGPGFGPGVVGVPGA-------------GVPGVGVPGAGIPVVPGA------ 357 G +PG PG PG G PG G PG+ +P G + G Sbjct: 307 GQPG--IPGLPG-DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363 Query: 358 -GIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF----- 407 G+PG PG+ P PG V G P G GFPG Sbjct: 364 PGLPGEKGERGFPGIQGPPGLP----------GPPGAAVMGPP----GPPGFPGERGQKG 409 Query: 408 -----GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG----VGTPA 458 G+ + G PG+ G PG G+PG G G I P + G G Sbjct: 410 DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469 Query: 459 AAAAKAAAKAAQFGLV-PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 517 K F + G+ PG PG+ PG PG G A G P Sbjct: 470 EQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP 529 Query: 518 GIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGV 577 GI PG A +K G PG+ G G G+PGL G Sbjct: 530 GI-PGAPGAPGFPGSK--------GEPGDILTFPGMKGDKGELGSPGAPGLPGL---PGT 577 Query: 578 PGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 637 PG +PG L K G G G G G G+PG + GP Sbjct: 578 PGQDGLPG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP-------- 628 Query: 638 QFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGV 697 G VG G+ G+ G G PG+ G G P + K G G G G G G+ Sbjct: 629 --GPVGEKGIQGV-AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGL 685 Query: 698 AARPGFGLSPIFPG 711 +PG P PG Sbjct: 686 PGQPGL---PGIPG 696 Score = 70.9 bits (172), Expect = 4e-12 Identities = 118/425 (27%), Positives = 142/425 (33%), Gaps = 84/425 (19%) Query: 291 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 349 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 350 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 409 G PG +PG PE G R G GIP G PG Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP-------GPPG--- 87 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAA 469 GI G G+PG G PG+ G+PG +P Q K G P + Sbjct: 88 -PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG-------- 138 Query: 470 QFGLVPGVGVAPGVGVAPGVGVAPG---VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAA 526 PG+ PG PG+ PG + PG PG PG+ P GP G+ Sbjct: 139 ----FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP--GPTGIPG 192 Query: 527 AAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA-----GVPGFG 581 G PGL G PGL G GL G G Sbjct: 193 PIGP-----------------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQ 235 Query: 582 AVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGL 641 PG K V G G G G PG GP K + + G Sbjct: 236 GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK--GEKGEQGE 293 Query: 642 VGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 701 G G G G G PG+ GL G P + + G G G G G P G V RP Sbjct: 294 PGKRGKPGKD-GENGQPGIPGLPG-DPGYPGEPGRDGEKGQKGDTGPPG--PPGLVIPRP 349 Query: 702 GFGLS 706 G G++ Sbjct: 350 GTGIT 354 >gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] Length = 1712 Score = 160 bits (404), Expect = 5e-39 Identities = 238/798 (29%), Positives = 305/798 (38%), Gaps = 131/798 (16%) Query: 23 PSRPG--GVPGAIPG------GVPGGV----FYPGAGLGALGGGALGPGGKPLKPVPGGL 70 P PG G PG G G+PG + F G+ AL GG GP GK P P GL Sbjct: 380 PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGL 439 Query: 71 AGA--------GL--GAGLGAFPAVT-FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVG 119 G GL G FP + PGA P G A + + + G+PG+ Sbjct: 440 PGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLP 499 Query: 120 GLGVSAGAVVPQPGAGVKPGKVPGVGLPGV-----YPGGV-LPGAR----------FPGV 163 G AG + +PG G GLPG PG + PG + G Sbjct: 500 GPKGFAG-INGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGE 558 Query: 164 GVLPGVPTGAGVKPK--APGVGG--AFAGIPGV------GPFGGP-QPGVPLGYPIKAPK 212 PGVP G+K +PG G F G+PG GP G P PG+P Sbjct: 559 RGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEM 618 Query: 213 LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAG 272 P G GLP G+ + G G+ G G G P G Q K A G Sbjct: 619 GPPGLGLPGLKGQRGFP-GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVG-GDRQEA 676 Query: 273 VLPG-VGGA-GVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGL-VPGGPG 328 + PG +GG G+PG+PG PG G G+ G P A A G A PG PG Sbjct: 677 IQPGCIGGPKGLPGLPGP-PGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPG 735 Query: 329 F-GP----GVVGVPGA-------GVPGV-------GVPGAGIPVVPG----AGIPGA--- 362 F GP G VG+PG G+PG G+PG + PG AG+PG Sbjct: 736 FIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGL 795 Query: 363 -AVPGVVSPEAAAKAAAKAAKYGAR--PGV-GVGGIP-TYGV-GAGGFPGFG-----VGV 411 +PG P + G + PG+ G G P YG G GFPG +G+ Sbjct: 796 KGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGL 855 Query: 412 GGIPGVAGVPGVGGVPGVGGVPGV----GISPEAQAAAAA-----------KAAKYGVGT 456 GIPG G+PG G PG G PG G+S + A K GT Sbjct: 856 PGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGT 915 Query: 457 PAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVA 516 P + + F +PG+ PG + G G+ G+ PG + G Sbjct: 916 PGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGP 975 Query: 517 PGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAG 576 PG P + ++ G G GL +G G+ G+PGL +G Sbjct: 976 PGPPP----------VILPGMKDIKGEKG-DEGPMGLKGYLGAKGIQGMPGIPGL---SG 1021 Query: 577 VPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKA 636 +PG PG + K K VPG+ G G G G PG G + A +A Sbjct: 1022 IPGLPGRPGHI---KGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRA 1078 Query: 637 AQFGLVGAAG-LGGLGVGGLGVPGVGGLGGIPPAAAAKAAK--YGAAGLGGVLGGAGQFP 693 +G +GA G G +G + +PG GL G K +G G G +G G Sbjct: 1079 GLYGEIGATGDFGDIG-DTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITG 1137 Query: 694 LGGVAARPGFGLSPIFPG 711 + GV PG FPG Sbjct: 1138 VTGVQGPPGLKGQTGFPG 1155 Score = 154 bits (389), Expect = 3e-37 Identities = 249/818 (30%), Positives = 294/818 (35%), Gaps = 148/818 (18%) Query: 21 LHPSRPGGVPGAIP---------GGVPGGVFYPGA-----GLGALGGGALGPGGKPLKPV 66 L P P G PG I GG PG GL L G G K L+ + Sbjct: 647 LGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGI 706 Query: 67 PGGLAGAGLGAGLGAFPAVT----FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL- 121 PG AGA G G P FPG PG + + K A G G PG GL Sbjct: 707 PG-FAGADGGPGPRGLPGDAGREGFPGP--PGFIGPRGS--KGAVGLPGPDGSPGPIGLP 761 Query: 122 ---GVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFP----GVGVLPGVPTGAG 174 G +P G +PG G+PG LPG R P G +PG+P G Sbjct: 762 GPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMP-GLK 820 Query: 175 VKPKAPGVGG--AFAGIPGVGPF-GGPQPGVPLGYPIKAPK--LPGGYGLPYTTGKL-PY 228 +P PG G G PG+ F G P PLG P + LPG G P TG P Sbjct: 821 GQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPV 880 Query: 229 GY----GPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVP 283 G G G AG G+ G+P G G + G G G G P Sbjct: 881 GMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRP 940 Query: 284 GVPGA--------IPGIGGIAGV-------------GTPAAAAAAAAAAKAAK------- 315 G PG+ IPG+ G+AG G P K K Sbjct: 941 GFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMG 1000 Query: 316 ---YGAAAGL--VPGGPGFG--PGVVGVPG--AGVPG-VGVPGA-GIPVVPG-AGIPG-A 362 Y A G+ +PG PG PG+ G PG GV G +GVPG G+P PG AG PG Sbjct: 1001 LKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGIT 1060 Query: 363 AVPGVVSPEAAAKAAAKAAKYG------------------ARPGV----GVGGIPTYGVG 400 PG + A +A YG RPG+ G GIP G Sbjct: 1061 GFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIP----G 1116 Query: 401 AGGFPGF-----GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVG 455 GF G +G GI GV GV G G+ G G PG+ P +Q G G Sbjct: 1117 LKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKG 1176 Query: 456 TPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPG-----VGVAPGVGLAPGVGVAPG-VGV 509 A + G+ PG PG + PG PG PG Sbjct: 1177 DDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANT 1236 Query: 510 APG-VGV--------APGI-GPGGVAAAAKSAAKVAAKAQLRAAAG-LGA-GIPGLGVGV 557 PG VGV APG GP G + + + + + A G GA GI GL Sbjct: 1237 LPGPVGVPGQKGDQGAPGERGPPG-SPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYR 1295 Query: 558 GVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGAAVPGVLGGLGALGGVGIPG 616 G PG A +PG G PG PG A + G PGV G G G G G Sbjct: 1296 GPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGR--PGVFGLPGEKGPRGEQG 1353 Query: 617 GVVGAGPAAAAAAAKAAAKAAQFGLVGAAG-LGGLGVGGL--------GVPGVGGLGGIP 667 + GP A G GA G +G G+ G+ G G G G P Sbjct: 1354 FMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPP 1413 Query: 668 --PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF 703 P G G G G AG GGV+A PGF Sbjct: 1414 GAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGF 1451 Score = 149 bits (376), Expect = 9e-36 Identities = 224/743 (30%), Positives = 271/743 (36%), Gaps = 128/743 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA-------GL 75 P PG V P G PG V G +GP G P +P P G G GL Sbjct: 186 PGEPGLVGFQGPPGRPGHV------------GQMGPVGAPGRPGPPGPPGPKGQQGNRGL 233 Query: 76 G-------------AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLG 122 G G P+ T + P GV YK K G G PG+ G+ Sbjct: 234 GFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEK---GSEGEPGIRGIS 290 Query: 123 VSA-GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPG 181 + ++ PG PG G PG L G + P P P G P PG Sbjct: 291 LKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDG---PRGPKGEAGDPGPPG 347 Query: 182 VGGAFAGIPGVGPFGGPQPGVP--LGYPIKA-----PKLPGGYGLPYTTGKLPYGY-GPG 233 + A++ P + PG P G P P LPG GL G G G Sbjct: 348 L-PAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEM 406 Query: 234 GVAGAAGKAGYPT--GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGV----GGAGVPGVPG 287 G G G G P G GP G G L G+ G AG PG+PG Sbjct: 407 GPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPG 466 Query: 288 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVP 347 + PG G G A +A K GL PG GF G+ G PG G P Sbjct: 467 S-PGARGPKGWKGDAGECRCTEGDEAIK--GLPGL-PGPKGFA-GINGEPGR-KGDRGDP 520 Query: 348 GA-GIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFP 405 G G+P PG G+PG G P+ A + G R GV G+P G G P Sbjct: 521 GQHGLPGFPGLKGVPGNI--GAPGPKGAKGDSRTITTKGERGQPGVPGVPGM-KGDDGSP 577 Query: 406 GFGVGVGGIPGVAGVPGVG-----GVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAA 460 G G+ G PG+ G PG G G PG G+PG +P + G+G P Sbjct: 578 GRD-GLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTP-------GEMGPPGLGLPGLK 629 Query: 461 AAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPG-----VGVAPGVGVAPGVGV 515 + PG PG PG PG PG V VG + Sbjct: 630 GQRG---------FPGDAGLPG---PPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAI 677 Query: 516 APGI--GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGV 573 PG GP G+ AK GL GIPG G PG G+PG Sbjct: 678 QPGCIGGPKGLPGLPGPPGPTGAK-------GL-RGIPGFAGADGGPG---PRGLPG--- 723 Query: 574 GAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGAL---------GGVGIPGGVVGAGPA 624 AG GF PG + + +K +PG G G + G G+PG V+GA P Sbjct: 724 DAGREGFPGPPGFI-GPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPG 782 Query: 625 AAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGAAGL 682 A + GL G G G G G+PG+ GL G P P + + YG GL Sbjct: 783 PRGDAGVPGQPGLK-GLPGDRGPPGFR-GSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGL 840 Query: 683 GGVLGGAGQ-FPLG--GVAARPG 702 G G GQ PLG G+ R G Sbjct: 841 HGFPGAPGQEGPLGLPGIPGREG 863 Score = 115 bits (287), Expect = 2e-25 Identities = 217/768 (28%), Positives = 264/768 (34%), Gaps = 169/768 (22%) Query: 44 PGAGLGALGGGALGP--GGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAA 101 P G GG P GG+ +P P G G GL FP + Sbjct: 41 PCGGRDCSGGCQCYPEKGGRG-QPGPVGPQGYNGPPGLQGFPGL---------------- 83 Query: 102 AYKAAKAGAGLGGVPGVGGLGVSAGA--VVPQPGAGVKPGKVPGVGLPGVYPG------- 152 + K G G PGV G GA V PGA PG PG G P PG Sbjct: 84 --QGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGH-PGQGGPRGRPGYDGCNGT 140 Query: 153 -GVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFA-------------GIPGVGPFGGP 198 G PG G P G K + G +A G PG+ F GP Sbjct: 141 QGDSGPQGPPGSEGFTGPPGPQGPKGQK---GEPYALPKEERDRYRGEPGEPGLVGFQGP 197 Query: 199 QPGVPLGY-----PIKAPKLPGGYGLPYTTGKLPY-GYGPGGVAGAAGKAGYPTGTGVGP 252 PG P G+ P+ AP PG G P G+ G G GV G G G P G+ Sbjct: 198 -PGRP-GHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPS 255 Query: 253 QAAAAAAAKAAAKF------GAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV----GT 300 A F G + PG+ G + G G + PG+ G G+ G+ Sbjct: 256 DTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGS 315 Query: 301 PAAAAAAAA-------AAKAAKYGAAAGLVPGGPGFGP---------GVVGVPGA-GVPG 343 P + + K A PG P + P G G PGA G PG Sbjct: 316 PGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPG 375 Query: 344 V-GVPG-AGIPVVPGAGIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGV-------G 390 G PG G+P PG I +PG + P+ A YG PG G Sbjct: 376 SQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPG 435 Query: 391 VGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG-VGISPEAQAAAAAKA 449 G+P G G GF G+ G G AG PG+ G PG G G G + E + +A Sbjct: 436 PPGLP----GPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEA 491 Query: 450 AKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV 509 K G P K A G+ PG G PG PG PG+ Sbjct: 492 IK---GLPGLPGPKGFA---------GINGEPG---RKGDRGDPGQHGLPGF---PGLKG 533 Query: 510 APGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVP 569 PG APG P G +++ + Q G+PG VPG+ G P Sbjct: 534 VPGNIGAPG--PKGAKGDSRTITTKGERGQ--------PGVPG------VPGMKGDDGSP 577 Query: 570 GLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-GVVGAGPAAAAA 628 G G PG PG K PG+ G G G +G PG G+ G Sbjct: 578 GRDGLDGFPGLPGPPGD--GIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGL------- 628 Query: 629 AAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGG--------------LGGIPPAAAAKA 674 Q G G AGL G G LG PG G +GG A Sbjct: 629 -------KGQRGFPGDAGLPG-PPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPG 680 Query: 675 AKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRK 722 G GL G+ G G G+ PGF + PG L GR+ Sbjct: 681 CIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGRE 728 Score = 101 bits (251), Expect = 3e-21 Identities = 154/494 (31%), Positives = 187/494 (37%), Gaps = 110/494 (22%) Query: 23 PSRPGGVPGA-----IPGGVPGGVFYPG-AGLGALGG--GALGPGGKPLKPVPGGLAGAG 74 P RPG + G +PG +PG +PG AG + G G +G G P GL G Sbjct: 1026 PGRPGHIKGVKGDIGVPG-IPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGE- 1083 Query: 75 LGAGLGAF----PAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV-- 128 +GA G F + PG PG K G G+PG+ G G Sbjct: 1084 IGA-TGDFGDIGDTINLPGR--PG-----------LKGERGTTGIPGLKGFFGEKGTEGD 1129 Query: 129 VPQPG----AGVK--PGKVPGVGLPGVY--PGGV-------LPGAR----FPGVGVLPGV 169 + PG GV+ PG G PG+ PG LPG + +PG LPG Sbjct: 1130 IGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGF 1189 Query: 170 PTGAGVKPK--APGVGGAFAGIPGVGPFGGPQ-PGVP--LGYPIKAPKLPGGYGLPYTTG 224 P G++ PG G F G PG G P PG P G P +A LPG G+P G Sbjct: 1190 PGLRGIRGLHGLPGTKG-FPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKG 1248 Query: 225 K--LPYGYGPGG---------------VAGAAGKAGYPTGTGV----GPQAAAAAAAKAA 263 P GP G ++GA G G P G+ GP +AA Sbjct: 1249 DQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPG 1308 Query: 264 AKFGAGAAGV--LPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAG 321 +K G G PG G P PG+ G+ G P GA Sbjct: 1309 SKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMG--NTGPTGAVGD 1366 Query: 322 LVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIP----VVPGA-------GIPGAAVPGVVS 369 P GP PG G PG VG PG AGIP V PG G PGA PG + Sbjct: 1367 RGPKGPKGDPGFPGAPGT----VGAPGIAGIPQKIAVQPGTVGPQGRRGPPGA--PGEMG 1420 Query: 370 PEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG-----VGVGGIPGVAGVPGVG 424 P+ + G R G G G G PGF +G G G G PG Sbjct: 1421 PQGPP------GEPGFRGAPGKAGPQGRG-GVSAVPGFRGDEGPIGHQGPIGQEGAPGRP 1473 Query: 425 GVPGVGGVPGVGIS 438 G PG+ G+PG +S Sbjct: 1474 GSPGLPGMPGRSVS 1487 Score = 60.8 bits (146), Expect = 4e-09 Identities = 94/308 (30%), Positives = 108/308 (35%), Gaps = 63/308 (20%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P PG PG G PG PG L G PG K + PG G GL Sbjct: 1208 PGSPGSDIHGDPGFPGPPGERGDPGEA-NTLPGPVGVPGQKGDQGAPGERGPPG-SPGLQ 1265 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK 140 FP +T P + + G D G PG+ GL G P PG+ PG Sbjct: 1266 GFPGIT-PPSNISGAPGDK--------------GAPGIFGLKGYRGPPGP-PGSAALPGS 1309 Query: 141 VPGVGLPGV--------YPGGVLPGARFPGVGVLPGV--------------PTGA--GVK 176 G PG + G P R PGV LPG PTGA Sbjct: 1310 KGDTGNPGAPGTPGTKGWAGDSGPQGR-PGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRG 1368 Query: 177 PKAPGVGGAFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 235 PK P F G PG VG PG+ G P K PG G G P G G Sbjct: 1369 PKGPKGDPGFPGAPGTVGA-----PGIA-GIPQKIAVQPGTVGPQGRRGP-PGAPGEMGP 1421 Query: 236 AGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGV--------LPG-VGGAGVPGV 285 G G+ G+ G GPQ +A + G G PG G G+PG+ Sbjct: 1422 QGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGM 1481 Query: 286 PGAIPGIG 293 PG IG Sbjct: 1482 PGRSVSIG 1489 Score = 57.0 bits (136), Expect = 6e-08 Identities = 85/323 (26%), Positives = 103/323 (31%), Gaps = 21/323 (6%) Query: 391 VGGIPTYGVGAGGFPGFG-------VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 + G+ + V GG G G G PG G G G PG+ G PG+ Sbjct: 32 LAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGL-------- 83 Query: 444 AAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGV 503 K K G P K A PG PG G PG G Sbjct: 84 -QGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQG 142 Query: 504 APGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLG 563 G PG G PG + A + R G PGL G PG Sbjct: 143 DSGPQGPPGSEGFTG-PPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRP 201 Query: 564 VGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVGAG 622 G G G PG PG G V G G +G G GIP + Sbjct: 202 GHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPI 261 Query: 623 PAAAAAAAKAAAKAAQFGLVGAAGLGGLGV-GGLGVPGVGGLGGIPPAAAAKAA--KYGA 679 A + G G G+ G+ + G G+ G GL G P + K + + G+ Sbjct: 262 IAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGS 321 Query: 680 AGLGGVLGGAGQFPLGGVAARPG 702 GL G G G G A PG Sbjct: 322 RGLDGYQGPDGPRGPKGEAGDPG 344 Score = 55.1 bits (131), Expect = 2e-07 Identities = 124/457 (27%), Positives = 140/457 (30%), Gaps = 104/457 (22%) Query: 339 AGVPGVGVPGAG---------IPVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGA 385 AGV VP G P G G PG P G + + G Sbjct: 33 AGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGE 92 Query: 386 RPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-------GIS 438 R GV G P VGA G GF PG G+PG G G G PG G S Sbjct: 93 RGAPGVTG-PKGDVGARGVSGF-------PGADGIPGHPGQGGPRGRPGYDGCNGTQGDS 144 Query: 439 --------------PEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLV-----PG--- 476 P Q K Y + P + + + GLV PG Sbjct: 145 GPQGPPGSEGFTGPPGPQGPKGQKGEPYAL--PKEERDRYRGEPGEPGLVGFQGPPGRPG 202 Query: 477 -VGVAPGVGVAPGVGVAPG------------------VGLAPGVGVAPGVGVAPGVGVAP 517 VG VG APG PG G VG PG P + P Sbjct: 203 HVGQMGPVG-APGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVG-QPGPNGIPSDTLHP 260 Query: 518 GIGPGGV--------------------AAAAKSAAKVAAKAQLRAAAGLGA--GIPGLGV 555 I P GV + K + LR GL G PG Sbjct: 261 IIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKG 320 Query: 556 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIP 615 G+ G G G AG PG +P AK PG G G G G P Sbjct: 321 SRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEP 380 Query: 616 GGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAA 675 G GP + + GL G G G +G PG+ L G PP K Sbjct: 381 GDPGLPGPPGLSIGDGDQRR----GLPGEMGPKGF----IGDPGIPALYGGPPGPDGKRG 432 Query: 676 KYGAAGLGGVLGGAG-QFPLGGVAARPGFGLSPIFPG 711 G GL G G G F L G R GF P PG Sbjct: 433 PPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPG 469 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 156 bits (395), Expect = 6e-38 Identities = 236/765 (30%), Positives = 268/765 (35%), Gaps = 121/765 (15%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG----GALGPGGKPLKPVPGGLAGAGLGAG 78 P P G G G PG V PG GA+G GA GP G P P G AG G Sbjct: 397 PEGPQGQRGET--GPPGPVGSPGLP-GAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPG 453 Query: 79 LGAFPAVTFPGALVPGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV 136 G+ P G+ K AG G PG G+ G + P G Sbjct: 454 P--------QGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGI---QGPIGPPGEEGK 502 Query: 137 K-PGKVPG-VGLPGVYPGGVLPGAR-FPGVGVLPGVPTGA----------GVK------- 176 + P PG VG PG PG R FPG LPG P GA G K Sbjct: 503 RGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPG-PKGAQGERGPVGSSGPKGSQGDPG 561 Query: 177 -PKAPGVGGA--FAGIPGV-------GPFGGP----QPGVPLGYPIKAPKLPGGYGLPYT 222 P PG+ GA G PGV GP G P +PG P I+ PG GLP Sbjct: 562 RPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQ--PGSMGLPGP 619 Query: 223 TGKL--PYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVL----- 274 G P G G AG G+ G P G VGP A + G G Sbjct: 620 KGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGL 679 Query: 275 ------PGVGGA----GVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVP 324 PG GG GVPG PGA+ +G G P + G A G P Sbjct: 680 PGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGP 739 Query: 325 GGPGFGPGVVGVPG-AGVPGV-GVPG-AGIPVVPG----------------AGIPGA-AV 364 GP PG G PG G PG+ G+PG GI PG AG GA + Sbjct: 740 DGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGL 799 Query: 365 PGVVSPEAAAKAAAKAAKYGARPGVG-VGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGV 423 PG + P A + + G R VG G G P VG G G G PGV Sbjct: 800 PGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGV 859 Query: 424 GGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPG----VGV 479 G PG G G SP Q A + G P + PG VG Sbjct: 860 KGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVG- 918 Query: 480 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKA 538 PG APG G PG PG+ PG G GP G Sbjct: 919 PPGPAGAPGPAGPLG---EPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDG 975 Query: 539 QLRAAAGLG-AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGA 597 Q G AG G VG+PG G+PGL AG PG GA Sbjct: 976 QPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATG-------DK 1028 Query: 598 AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGV 657 PG +G G+ G VG PG AG A + G G AGL G G Sbjct: 1029 GPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL----PGSQGA 1084 Query: 658 PGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 PG G P A A + G G G +G G+ G+ G Sbjct: 1085 PGTPG----PVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQG 1125 Score = 135 bits (340), Expect = 1e-31 Identities = 228/740 (30%), Positives = 267/740 (36%), Gaps = 136/740 (18%) Query: 23 PSRPG--GVPGAIPGGVPG--GVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAG 78 P RPG G+PGA G+ G GV P LG LG A G G+P P G+ G G Sbjct: 560 PGRPGEPGLPGA--RGLTGNPGVQGPEGKLGPLG--APGEDGRPGPPGSIGIRGQPGSMG 615 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVK 137 L PG G D +A AG G G PG G +G V P PG + Sbjct: 616 L--------PGP--KGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP-PGLAGE 664 Query: 138 PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFG 196 G+ G PG P G F G+ PG P G G KP GV G PG VGP G Sbjct: 665 RGEQ---GPPG--PTG------FQGLPGPPG-PPGEGGKPGDQGVPGD----PGAVGPLG 708 Query: 197 GPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV------ 250 P G P + + PG GLP G + G+GP G G+ G +G P TG Sbjct: 709 ---PRGERGNPGERGE-PGITGLPGEKG-MAGGHGPDGPKGSPGPSGTPGDTGPPGLQGM 763 Query: 251 -GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAG---------- 297 G + A + G G G G G G+PG + PG G G Sbjct: 764 PGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGL 823 Query: 298 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----------------AGV 341 VG P + + + GA P GP PGV G PG AG Sbjct: 824 VGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGS 883 Query: 342 PGV----GVPGA----GIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV--- 389 PG GVPG G PGA G PG+A G V P A A A G PG Sbjct: 884 PGPHGPNGVPGLKGGRGTQGPPGATGFPGSA--GRVGPPGPAGAPGPAGPLG-EPGKEGP 940 Query: 390 -GVGGIP-TYGV----GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQ 442 G+ G P ++G G G PG G G G PG G PG G PG G G GI Sbjct: 941 PGLRGDPGSHGRVGDRGPAGPPG-GPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIV--GM 997 Query: 443 AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAP----GVGVAPGVGVAPGVGLA 498 + G+ PA K A P V P G PG G Sbjct: 998 PGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGT 1057 Query: 499 PGVGVA---------PGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAG 549 PG A PG PG APG PG V A + + G Sbjct: 1058 PGRDGAVGERGDRGDPGPAGLPGSQGAPGT-PGPVGAPGDAGQR---------------G 1101 Query: 550 IPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGA--AVPGVLGGLG 607 PG +G PG G+PG G G G + +PG G G Sbjct: 1102 DPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNG 1161 Query: 608 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 667 G GIPG GP + G +G G+ G VG G G G G P Sbjct: 1162 EQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRG-SVGEAGPEGPPGEPG-P 1219 Query: 668 PAAAAKAAKYGAAGLGGVLG 687 P AA LG ++G Sbjct: 1220 PGPPGPPGHLTAA-LGDIMG 1238 Score = 129 bits (323), Expect = 1e-29 Identities = 227/765 (29%), Positives = 268/765 (35%), Gaps = 136/765 (17%) Query: 11 PGVLLLLLSILHPSRPGGVPGAI-PGGVPGGVFYPGA----GLGALGG-----GALGPGG 60 PG++ ++ I P G PG+ P G G PG G+ G GA GP G Sbjct: 118 PGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPG 177 Query: 61 KPLKPVPGGLAG--AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGV 118 P P P GL+ + AGL + L+PG V G G G+ Sbjct: 178 HPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPV-----------GPRGPQGL 226 Query: 119 GGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPK 178 G AG P PG PG + +G G P G PG PG PG + Sbjct: 227 QGQQGGAGPTGP-PGEPGDPGPMGPIGSRG--PEGP-PGK--PGEDGEPG-------RNG 273 Query: 179 APGVGGAFAGIPGVGPFGGPQPGVP-----LGYP-IKAPKLPGGYGLPYTTGKLPYGYGP 232 PG G FAG PG F G PG+P G+ ++ PK G G P + G+ GP Sbjct: 274 NPGEVG-FAGSPGARGFPGA-PGLPGLKGHRGHKGLEGPK--GEVGAPGSKGEAG-PTGP 328 Query: 233 GGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPG--- 287 G G G G P G +GPQ A PG GA G+PG PG Sbjct: 329 MGAMGPLGPRGMPGERGRLGPQGA-------------------PGQRGAHGMPGKPGPMG 369 Query: 288 --AIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPG 343 IPG G G G A A G P GP PG+ G G G PG Sbjct: 370 PLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPG 429 Query: 344 ----VGVPGAGIPVVPG-AGIPGAAVP-GVVSPEAAAKAAAKAAKYGARPGVGVGGIP-T 396 G PG P PG AG PG+ P G P+ G + G G P Sbjct: 430 AKGPTGSPGTSGP--PGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGP 487 Query: 397 YGV-------------GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 +G+ G G PG VG G G G PG G PG G+PG + + Sbjct: 488 HGIQGPIGPPGEEGKRGPRGDPG-TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERG 546 Query: 444 AAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGV 503 + K G P A GL GV G +G APG PG Sbjct: 547 PVGSSGPKGSQGDPGRPGEPGLPGAR--GLTGNPGVQGPEGKLGPLG-APGEDGRPGPPG 603 Query: 504 APGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG-------AGIPGLGV 555 + G+ PG PG G G A Q A G G PGL Sbjct: 604 SIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAG 663 Query: 556 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIP 615 G G G GL G PG G PG PG +G LG G G P Sbjct: 664 ERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGV-------PGDPGAVGPLGPRGERGNP 716 Query: 616 G-----GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL-GGLGVGGL-GVPGVGGLGGIP- 667 G G+ G P A + G G +G G G GL G+PG G+ G P Sbjct: 717 GERGEPGITGL-PGEKGMAGGHGPDGPK-GSPGPSGTPGDTGPPGLQGMPGERGIAGTPG 774 Query: 668 ----------PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 A A GA GL G LG G G PG Sbjct: 775 PKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPG 819 Score = 87.4 bits (215), Expect = 4e-17 Identities = 126/465 (27%), Positives = 161/465 (34%), Gaps = 59/465 (12%) Query: 276 GVGGAGVPGVPGAIPGIGGIAGVGTPAA-AAAAAAAAKAAKYGAAAGLVPGGPGFGPGVV 334 G G G G PG +P + GI G PA + + G P G PGV Sbjct: 108 GRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVP 167 Query: 335 GVPGA-GVPG-VGVPG------------AGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKA 380 G PGA G PG PG AG+ G G +PG V P Sbjct: 168 GQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQ 227 Query: 381 AKYGARPGVG----------VGGIPTYG-------------VGAGGFPGFGVGVGGIPGV 417 + G G +G I + G G G PG VG G PG Sbjct: 228 GQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPG-EVGFAGSPGA 286 Query: 418 AGVPGVGGVPGVGGVPG-VGI-SPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 475 G PG G+PG+ G G G+ P+ + A + G P A + +P Sbjct: 287 RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRG-----MP 341 Query: 476 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKV 534 G G APG A G+ PG G+ + G PG+ G G A Sbjct: 342 GERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQ 401 Query: 535 AAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA-----LA 588 + + +G+ G+PG G PG G PG +G PG PG+ Sbjct: 402 GQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGT---SGPPGSAGPPGSPGPQGST 458 Query: 589 AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG-L 647 + + PGV G G G G PG GP G VG G + Sbjct: 459 GPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPV 518 Query: 648 GGLGV-GGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQ 691 G G G G PG GL G P A + G++G G G G+ Sbjct: 519 GERGAPGNRGFPGSDGLPG-PKGAQGERGPVGSSGPKGSQGDPGR 562 Score = 75.5 bits (184), Expect = 2e-13 Identities = 117/385 (30%), Positives = 137/385 (35%), Gaps = 77/385 (20%) Query: 325 GGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKY 383 G FG G G G PG+ +PVV G G PG A P P + + K Sbjct: 103 GNTNFGRGRKGQKGE--PGL------VPVVTGIRGRPGPAGP----PGSQGPRGERGPK- 149 Query: 384 GARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQ 442 RPG P G+ G PGV G PG G PG PG G+S Sbjct: 150 -GRPG----------------PRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFS 192 Query: 443 AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG 502 A A K G+G+ Q GL+PG V P VG GL G Sbjct: 193 AQMAGLDEKSGLGS-------------QVGLMPG-------SVGP-VGPRGPQGLQGQQG 231 Query: 503 VAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG----AGIPGLGVGV 557 A G PG PG +GP G K + G AG PG Sbjct: 232 GAGPTG-PPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFP 290 Query: 558 GVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG 617 G PGL PGL G G G + A +K A G +G +G LG G+PG Sbjct: 291 GAPGL------PGLKGHRGHKGLEGPKGEVGAP-GSKGEAGPTGPMGAMGPLGPRGMPGE 343 Query: 618 VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY 677 GP A Q G G G G +G LG+PG G G P +A Sbjct: 344 RGRLGPQGA---------PGQRGAHGMPGKPG-PMGPLGIPGSSGFPG-NPGMKGEAGPT 392 Query: 678 GAAGLGGVLGGAGQFPLGGVAARPG 702 GA G G G G+ G PG Sbjct: 393 GARGPEGPQGQRGETGPPGPVGSPG 417 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 150 bits (380), Expect = 3e-36 Identities = 174/554 (31%), Positives = 203/554 (36%), Gaps = 66/554 (11%) Query: 111 GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVP 170 G G PG G G PG PGK PG G PG+ LPG P PGVP Sbjct: 57 GEQGTPGPPGPAGPRG----HPGPSGPPGK-PGYGSPGLQGEPGLPGPPGPSAVGKPGVP 111 Query: 171 TGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGY 230 P PG G + VGP G P P P G P +PG G+ +P Sbjct: 112 G----LPGKPGERGPYGPKGDVGPAGLPGPRGPPG----PPGIPGPAGI-----SVPGKP 158 Query: 231 GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIP 290 G G GA G G+P G P K +GA G+ G P P P Sbjct: 159 GQQGPTGAPGPRGFPGEKGA-PGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPP 217 Query: 291 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV-GVPGA 349 G+G G P + G P GP PG G G G PG G PG Sbjct: 218 GVGKRGENGVPGQPGIKGDRGFPGEMGPIG---PPGPQGPPGERGPEGIGKPGAAGAPGQ 274 Query: 350 GIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV--GAGGFPG 406 P +PG G+PGA PG+ P PG G G+P G G PG Sbjct: 275 --PGIPGTKGLPGA--PGIAGPPGP-------------PGFGKPGLPGLKGERGPAGLPG 317 Query: 407 FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAA 466 G G G G AG+PG PG+ G PG + P+ K G P A Sbjct: 318 -GPGAKGEQGPAGLPGK---PGLTGPPG-NMGPQGP-----KGIPGSHGLPGPKGETGPA 367 Query: 467 KAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVA 525 A + G +PG PG PG+ G PG PGVG PG+ GP G Sbjct: 368 GPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVG-P 426 Query: 526 AAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG 585 A AK +A R A GIPG +G P G+PG G PG PG Sbjct: 427 AGAKGMPGHNGEAGPRGA----PGIPGTRGPIGPP------GIPGFPGSKGDPGSPGPPG 476 Query: 586 -ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGA 644 A A K PG G G G G+PG GP A + KA Q + Sbjct: 477 PAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSG 536 Query: 645 AGLGGLGVGGLGVP 658 L G G+P Sbjct: 537 TPLVSANQGVTGMP 550 Score = 124 bits (310), Expect = 4e-28 Identities = 179/566 (31%), Positives = 215/566 (37%), Gaps = 102/566 (18%) Query: 28 GVPG-AIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG A P G PG P G G G+ G G+P P P G + G G+ P Sbjct: 63 GPPGPAGPRGHPG----PSGPPGKPGYGSPGLQGEPGLPGPPGPSAVG-KPGVPGLPGK- 116 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPG----VGGLGVSAGAVVPQPGAGVKPGKVP 142 PG P G K G G+PG G G+ A + PG KPG+ Sbjct: 117 -PGERGPYG----------PKGDVGPAGLPGPRGPPGPPGIPGPAGISVPG---KPGQQG 162 Query: 143 GVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPK----APGVGGAFAGIPGVGPFGGP 198 G PG P G FPG PGVP G K + APG G G+P GP G Sbjct: 163 PTGAPG--PRG------FPGEKGAPGVPGMNGQKGEMGYGAPGRPGE-RGLP--GPQGPT 211 Query: 199 QPGVPLGYPIKAPK-LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAA 257 P P G + +PG G+ G P GP G G G G G+G AA Sbjct: 212 GPSGPPGVGKRGENGVPGQPGIKGDRG-FPGEMGPIGPPGPQGPPGERGPEGIGKPGAAG 270 Query: 258 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-AIPGIGGIAGVGTPAAAAAAAAAAKAAKY 316 A + G G PG+ AG PG PG PG+ G+ G PA Sbjct: 271 APGQPGIPGTKGLPGA-PGI--AGPPGPPGFGKPGLPGLKGERGPAG------------- 314 Query: 317 GAAAGLVPGGPGF--GPGVVGVPGAGVPGV-GVPGAGIPVVPGAGIPGA-AVPGVVSPEA 372 +PGGPG G G+PG PG+ G PG P P GIPG+ +PG Sbjct: 315 ------LPGGPGAKGEQGPAGLPGK--PGLTGPPGNMGPQGP-KGIPGSHGLPGPKGETG 365 Query: 373 AAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGV 432 A A G R G G P G+PG G+ G G G+PG G PGVGG Sbjct: 366 PAGPAGYPGAKGERGSPGSDGKP-------GYPG-KPGLDGPKGNPGLPGPKGDPGVGGP 417 Query: 433 PGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVA 492 PG+ P A A G P A + G PG+ PG PG Sbjct: 418 PGLP-GPVGPAGAKGMPGHNGEAGPRGAPGIPGTR-GPIG-PPGIPGFPGSKGDPGSPGP 474 Query: 493 PG-VGLA----------PGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQL 540 PG G+A PG G PG+ PG GP G A + K + L Sbjct: 475 PGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSL 534 Query: 541 RAAAGLGAGIPGLGVGVGVPGLGVGA 566 +G P + GV G+ V A Sbjct: 535 -------SGTPLVSANQGVTGMPVSA 553 Score = 118 bits (295), Expect = 2e-26 Identities = 165/498 (33%), Positives = 195/498 (39%), Gaps = 81/498 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGL-------GALGGGALG-PG--GKPLKPVPGGLAG 72 P+ P G PG P G PG Y GL G G A+G PG G P KP G G Sbjct: 67 PAGPRGHPG--PSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYG 124 Query: 73 AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQ 131 G P P P G+ A K G G G PG G GA Sbjct: 125 PKGDVGPAGLPGPRGPPG--PPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAP-GV 181 Query: 132 PGAGVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGV-PTGAGVKPKAPGVGGAFAGI 189 PG + G++ G G PG LPG + P G PGV G P PG+ G G Sbjct: 182 PGMNGQKGEM-GYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGD-RGF 239 Query: 190 PG-VGPFGGPQPGVP--------LGYPIKA-----PKLPGGYGLPYTTGKL----PYGYG 231 PG +GP G P P P +G P A P +PG GLP G P G+G Sbjct: 240 PGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFG 299 Query: 232 -PG--GVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 287 PG G+ G G AG P G G G Q A K G G +G G G+PG Sbjct: 300 KPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKP------GLTGPPGNMGPQGPKGIPG 353 Query: 288 A--IPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGF-GP-GVVGVPGA-GVP 342 + +PG G G PA A + G PG PG GP G G+PG G P Sbjct: 354 SHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGY-PGKPGLDGPKGNPGLPGPKGDP 412 Query: 343 GVG----VPG----AGIPVVPG----------AGIPGAAVPGVVSPEAAAKAAAKAAKYG 384 GVG +PG AG +PG GIPG P + P G Sbjct: 413 GVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGP--IGPPGIPGFPGSKGDPG 470 Query: 385 ARPGVGVGGIPTYGV-GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 + G GI T G+ G G PG G G +G PG+ G PG G PG + PE Sbjct: 471 SPGPPGPAGIATKGLNGPTGPPG----PPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFI 526 Query: 444 AAAAKAAKYGVGTPAAAA 461 A + + GTP +A Sbjct: 527 KAGQRPSL--SGTPLVSA 542 Score = 115 bits (289), Expect = 1e-25 Identities = 163/547 (29%), Positives = 196/547 (35%), Gaps = 112/547 (20%) Query: 193 GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGY----GPGGVAGAAGKAGYPTGT 248 G F + +P G P + +PYT G G G AG G+P Sbjct: 18 GVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHP--- 74 Query: 249 GVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAA 308 GP +G G PG G G+ G PG +PG G + VG P Sbjct: 75 --GP---------------SGPPGK-PGYGSPGLQGEPG-LPGPPGPSAVGKPGVPGLPG 115 Query: 309 AAAKAAKYGAAAGLVPGG---PGFGPGVVGVPG-AGVPGVGVPGAGIPV-VPGA-GIPGA 362 + YG + P G P PG G+PG AG+ G PG P PG G PG Sbjct: 116 KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGE 175 Query: 363 -AVPGVVSPEAAAKAAAKAAKYGA--RPGV-GVGGIPTYGVGAGGFPGFGV-GVGGIPGV 417 PGV YGA RPG G+ G P G G PG G G G+PG Sbjct: 176 KGAPGVPGMNGQKGEMG----YGAPGRPGERGLPG-PQGPTGPSGPPGVGKRGENGVPGQ 230 Query: 418 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 477 G+ G G PG G I P + G+G P AA A PG+ Sbjct: 231 PGIKGDRGFPGEMGP----IGPPGPQGPPGERGPEGIGKPGAAGAPGQ---------PGI 277 Query: 478 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAK 537 G+ APG+ PG PG G PG+ G G+ PGG A + Sbjct: 278 PGTKGLPGAPGIAGPPG---PPGFG-KPGLPGLKGERGPAGL-PGGPGAKGEQGP----- 327 Query: 538 AQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGA 597 AG+PG PGL G G G+PG +PG A A Sbjct: 328 ----------AGLPGK------PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAG-PA 370 Query: 598 AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGV 657 PG G G+ G G PG + GL G G GL G G Sbjct: 371 GYPGAKGERGSPGSDGKPG------------------YPGKPGLDGPKGNPGLP-GPKGD 411 Query: 658 PGVGGLGGIP----PAAA-------AKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLS 706 PGVGG G+P PA A +A GA G+ G G G + G G S Sbjct: 412 PGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS 471 Query: 707 PIFPGGA 713 P PG A Sbjct: 472 PGPPGPA 478 Score = 114 bits (285), Expect = 3e-25 Identities = 144/460 (31%), Positives = 175/460 (38%), Gaps = 53/460 (11%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAG-----LGA 77 P P G PG IPG P G+ PG GA GP G P + G+ G +G Sbjct: 137 PRGPPGPPG-IPG--PAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY 193 Query: 78 GLGAFPAVT-FPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAG 135 G P PG P G + K + G G G+ G G G + P PG Sbjct: 194 GAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGP-PGPQ 252 Query: 136 VKPGK--VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 193 PG+ G+G PG PG PG LPG P AG P PG G G+PG+ Sbjct: 253 GPPGERGPEGIGKPGAAGAPGQPG--IPGTKGLPGAPGIAG-PPGPPGFGKP--GLPGLK 307 Query: 194 PFGGPQPGVPLGYPIKAPKLPGGY-GLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 252 GP G+P G K + P G G P TG P GP G G G G P G Sbjct: 308 GERGPA-GLPGGPGAKGEQGPAGLPGKPGLTGP-PGNMGPQGPKGIPGSHGLPGPKGETG 365 Query: 253 QAAAAAAAKAAAKFGAGAAGVLPGVGGA-------GVPGVPG--AIPGIGGIAGVGTPAA 303 A A A + G+ + PG G G PG+PG PG+GG G+ P Sbjct: 366 PAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVG 425 Query: 304 AAAAAAAAKAAKYGAAAGLVPGGPG-FGP-GVVGVPGAGVPGVGVPGAGIPVVPGA---- 357 A A +PG G GP G G+PG P +G PG IP PG+ Sbjct: 426 PAGAKG-------------MPGHNGEAGPRGAPGIPGTRGP-IGPPG--IPGFPGSKGDP 469 Query: 358 GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGV 417 G PG P ++ + G R G G+P G G PG V G Sbjct: 470 GSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPG-PPGPPGPPGQAVMPEGFIKA 528 Query: 418 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTP 457 P + G P V GV P + A +GTP Sbjct: 529 GQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTP 568 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 149 bits (375), Expect = 1e-35 Identities = 228/779 (29%), Positives = 273/779 (35%), Gaps = 127/779 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGA-GLGA-- 77 P PG G PG + PG L G G GP G P P P G GA GL Sbjct: 538 PGPPGRDGSKGMRGEPGELGEPG-----LPGEVGMRGPQGPPGLPGPPGRVGAPGLQGER 592 Query: 78 ------------GLGAFPA----VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL 121 GL FP G P GVA + K G G PGV G Sbjct: 593 GEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP----QGEKGDVGPAGPPGVPGS 648 Query: 122 GVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAP 180 V + + GA PG G PG PGAR P G G P G++ K Sbjct: 649 VVQQEGLKGEQGA---PGPRGHQGAPGP------PGARGPIGPEGRDGPPGLQGLRGKKG 699 Query: 181 GVGGAFAGIPGVGPFGGP--QPGVP-LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG 237 +G GIPG+ GP PGVP P +P LPG G P G P GP G G Sbjct: 700 DMGP--PGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGP-PGPTGPPGKDG 756 Query: 238 AAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIA 296 G G P G G + K + G G+ G G G+PGA PG G+ Sbjct: 757 PNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA-PGFPGVR 815 Query: 297 G-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG------- 348 G G G P GP PG+ G P +PG Sbjct: 816 GEKGDQGEKGELGLPGLKGDRGEKGEAGPAGP---PGLPGTTSLFTPHPRMPGEQGPKGE 872 Query: 349 ---AGIPVVPG-AGIPG-------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY 397 G+P PG G PG PG E A A A GA VG G P+ Sbjct: 873 KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPG-PSG 931 Query: 398 GVGAGGFPGF--------------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 G+ G PG G G PG G G G PG+ G PG G E Sbjct: 932 PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGE-PG 990 Query: 444 AAAAKAAKYGVGTPAAAAAKAAAKAAQFG--LVPGVGVAPGVGVAPGVGVAPGVGLA--P 499 + +GT AA ++ G V G APG+ +PG PG+G+A P Sbjct: 991 LRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPP 1050 Query: 500 GVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAK--VAAKAQLRAAAGLG------ 547 G PG +PG PG GP G A + + K L + G Sbjct: 1051 GPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLA 1110 Query: 548 --------------AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 593 G+PG GVPG G G AG PG PG +A + + Sbjct: 1111 KDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG-IAGPQGS 1169 Query: 594 KYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL----GG 649 + G +G G G G+PG + G A A A G+ G+ G G Sbjct: 1170 QGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGP 1229 Query: 650 LGVGGL-GVPGVGGLGGI-----PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 G GL G+PG G G PP KA + G G G G G G + PG Sbjct: 1230 QGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPG 1288 Score = 147 bits (371), Expect = 3e-35 Identities = 213/744 (28%), Positives = 260/744 (34%), Gaps = 131/744 (17%) Query: 17 LLSILHPSRPGGVPGAIPG-----GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLA 71 LL + P P GVPG PG G+PG + +PG G GP G P K P G Sbjct: 709 LLGLQGPPGPPGVPGP-PGPGGSPGLPGEIGFPGKP------GPPGPTGPPGKDGPNGPP 761 Query: 72 GAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ 131 G PG K G G+PG GL G + Sbjct: 762 GP--------------PGT-------------KGEPGERGEDGLPGKPGLRGEIG----E 790 Query: 132 PGAGVKPGKVPGVGLPGVYPGGVLPGARFP-------GVGVLPGVPTGAGVKPKAPGVGG 184 G +PG+ GLPG PG PG R G LPG+ G K +A G Sbjct: 791 QGLAGRPGEKGEAGLPGA-PG--FPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGP 847 Query: 185 AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY 244 G+PG P P +P K K G GLP G G+ G G+ G Sbjct: 848 P--GLPGTTSLFTPHPRMPGEQGPKGEK--GDPGLP----------GEPGLQGRPGELGP 893 Query: 245 PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAA 303 GP A + A GAAG G G PG P PG G G+ GTP Sbjct: 894 Q-----GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPG-PSGPPGSVGAPGLRGTPGK 947 Query: 304 AAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPGAGIPGA 362 A + G+ + P G PG+ G PG G G PG G P +PG + Sbjct: 948 DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKD--GEPGLRGSPGLPGP-LGTK 1004 Query: 363 AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPG 422 A G V + K G R G+ G P G+ G P G+GV G PG +G PG Sbjct: 1005 AACGKVRGSENCALGGQCVK-GDRGAPGIPGSP----GSRGDP--GIGVAGPPGPSGPPG 1057 Query: 423 VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGV-GTPAAAAAKAAAKAAQFGLV------- 474 G PG G+PG P+ A G G P + L+ Sbjct: 1058 DKGSPGSRGLPGFP-GPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCND 1116 Query: 475 --PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSA 531 PG PG+ PG GV PG G G PG+ GP G+A S Sbjct: 1117 CPPG---PPGLPGLPGFKGDKGV---PGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQ 1170 Query: 532 AKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG----- 585 + A ++ G G+PG +G PG G G+ AG PG PG Sbjct: 1171 GERGADGEVGQKGDQGHPGVPGF---MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPP 1227 Query: 586 ---------ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP------AAAAAAA 630 + + + PG G G G G+PG GP + A Sbjct: 1228 GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAP 1287 Query: 631 KAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGG 688 ++ GL G GL G G G G G G PP G G G G Sbjct: 1288 GPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRG-PPGKNGSPGSPGEPGPSGTPGQ 1346 Query: 689 AGQFPLGGVAARPGFGLSPIFPGG 712 G G PGF L P P G Sbjct: 1347 KGSKGENGSPGLPGF-LGPRGPPG 1369 Score = 119 bits (299), Expect = 8e-27 Identities = 196/658 (29%), Positives = 240/658 (36%), Gaps = 97/658 (14%) Query: 107 KAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVL 166 K G+ G G+ G GA+ P G K K G G+ P G +G L Sbjct: 483 KGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEK----GDVGIGPFGQGEKGEKGSLG-L 537 Query: 167 PGVPTGAGVKPKA--PGVGGAFAGIPGVGPFGGPQ--PGVPLGYP--IKAPKLPGGYGLP 220 PG P G K PG G G+PG GPQ PG+P G P + AP L G G Sbjct: 538 PGPPGRDGSKGMRGEPGELGE-PGLPGEVGMRGPQGPPGLP-GPPGRVGAPGLQGERGEK 595 Query: 221 YTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA 280 T G+ G G+ G GK G TG P + A G G VG A Sbjct: 596 GTRGEK----GERGLDGFPGKPG-DTGQQGRPGPSGVA----------GPQGEKGDVGPA 640 Query: 281 GVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG- 338 G PGVPG++ G+ G G P A GA + P G PG+ G+ G Sbjct: 641 GPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPP---GARGPIGPEGRDGPPGLQGLRGK 697 Query: 339 ------AGVPGV----GVPG-AGIPVVPG----AGIPG-AAVPGVVSPEAAAKAAAKAAK 382 G+PG+ G PG G+P PG G+PG PG P K Sbjct: 698 KGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGP 757 Query: 383 YGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQ 442 G G G P G G PG G+ G G G+ G G G G+PG P + Sbjct: 758 NGPPGPPGTKGEPGER-GEDGLPG-KPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVR 815 Query: 443 AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPG-VGVAPGVGVAPGVGLAPGV 501 + K +G P + A PG+ PG + PG G Sbjct: 816 GEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGL---PGTTSLFTPHPRMPGEQGPKGE 872 Query: 502 GVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGV 559 PG+ PG+ PG +GP G AK Q A G AG PG VG Sbjct: 873 KGDPGLPGEPGLQGRPGELGPQG------PTGPPGAKGQEGAHGAPGAAGNPGAPGHVGA 926 Query: 560 PGLGVGAGVPGLGVGAGVPGFGAVPG--ALAAAKAAKYGAAVPGVLGGLGALGGVGIPG- 616 PG +G PG G PG PG K A PG +G G G G+PG Sbjct: 927 PG---PSGPPG---SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGP 980 Query: 617 ---------GVVGA----GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL-------G 656 G+ G+ GP AA + L G G G G+ G Sbjct: 981 PGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRG 1040 Query: 657 VPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAG-QFPLG--GVAARPGFGLSPIFPG 711 PG+G G PP + G+ G G+ G G Q P G G PG P PG Sbjct: 1041 DPGIGVAG--PPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPG 1096 Score = 112 bits (280), Expect = 1e-24 Identities = 208/737 (28%), Positives = 248/737 (33%), Gaps = 116/737 (15%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPG-----------AGLGALGG----GALGPGGKPLKPV 66 +P PG V P G PG V PG GA G G +GP G P P Sbjct: 917 NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 976 Query: 67 PGGLAGAGLGAGLGAFPAVTFPGALVPG-------GVADAAAAYKAAKAGAGLGGVPGVG 119 G G G G + PG L G + A + K G G+PG Sbjct: 977 LPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSP 1036 Query: 120 GLGVSAG-AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPK 178 G G V PG PG G G LPG FPG P P G P Sbjct: 1037 GSRGDPGIGVAGPPGPSGPPGDKGSPGSRG------LPG--FPG----PQGPAGRDGAPG 1084 Query: 179 APGVGGAFAGIPGVGPFGGPQP----------GVPLGYPIKAPKLPGGYGLPYTTGKLPY 228 PG G G PG+ P P G P P LPG G GK P Sbjct: 1085 NPGERGP-PGKPGLSSLLSPGDINLLAKDVCNDCPPGPP-GLPGLPGFKGDKGVPGK-PG 1141 Query: 229 GYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGG-AGVPGVPG 287 G G G AG G P G+ + A + G PGV G G PG PG Sbjct: 1142 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPG 1201 Query: 288 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL--VPG-----------GPGFGPGVV 334 PG GIAG P + +GL +PG GP PG Sbjct: 1202 P-PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKA 1260 Query: 335 GVPGA-------GVPGV-------GVPG----AGIPVVPGA-GIPG----AAVPGVVSPE 371 G PG G PG G PG +G +PG G+PG G P+ Sbjct: 1261 GEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQ 1320 Query: 372 AAAKAAAKAAKYGARPGVGVGGIPTYGVGAG-----GFPGF--GVGVGGIPGVAGVPGVG 424 K G+ G G P G G PGF G G PG GVPG Sbjct: 1321 GPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKE 1380 Query: 425 GVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVG 484 GVPG G PG K G G P GL+ G+ PG Sbjct: 1381 GVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPG--IPGHKGHTGLMGPQGL-PGEN 1437 Query: 485 VAPGVGVAPGVGLAPGV-GVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAA 543 G PG PG+ G +P + + + +G A A++ A ++++ Sbjct: 1438 GPVGPPGPPGQPGFPGLRGESPSMETLRRL-IQEELGKQLETRLAYLLAQM-PPAYMKSS 1495 Query: 544 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 603 G G PG G+PG G PG G+ G + P + AK PGV Sbjct: 1496 QG-RPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEG-PSGPIGPKGERGAKGDPGAPGV- 1552 Query: 604 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGL 663 G G +G GIPG G A+ GL G G G G G PG+ G Sbjct: 1553 GLRGEMGPPGIPGQPGEPG-------------YAKDGLPGIPGPQG-ETGPAGHPGLPGP 1598 Query: 664 GGIPPAAAAKAAKYGAA 680 G P Y A+ Sbjct: 1599 PGPPGQCDPSQCAYFAS 1615 Score = 100 bits (249), Expect = 5e-21 Identities = 162/547 (29%), Positives = 193/547 (35%), Gaps = 63/547 (11%) Query: 215 GGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGA-----G 269 G GLP G + G G GA G G G+GP K + G Sbjct: 490 GPMGLPGPKGDI----GAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDG 545 Query: 270 AAGVLPGVGGAGVPGVPGAI--------PGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAA 320 + G+ G G PG+PG + PG+ G G VG P + G Sbjct: 546 SKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGER- 604 Query: 321 GL--VPGGPGFG-----PGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAA 373 GL PG PG PG GV G V AG P VPG+ + + G Sbjct: 605 GLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGP 664 Query: 374 AKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG 431 GAR +G G P G G G +G GIPG+ G+ G G PGV G Sbjct: 665 RGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKG-DMGPPGIPGLLGLQGPPGPPGVPG 723 Query: 432 VPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGV 491 PG G SP K G P K PG PG G+ Sbjct: 724 PPGPGGSPGLPGEIGFPG-KPGPPGPTGPPGKDGPNGPPGP--PGTKGEPGERGEDGLPG 780 Query: 492 APGV-GLAPGVGVA--PGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA 548 PG+ G G+A PG G+ APG PG K +L Sbjct: 781 KPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF-PG----VRGEKGDQGEKGEL-------- 827 Query: 549 GIPGLGVGVGVPGLGVGAGVPGL-GVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLG 607 G+PGL G G AG PGL G + +PG K K +PG G G Sbjct: 828 GLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGE-QGPKGEKGDPGLPGEPGLQG 886 Query: 608 ALGGVGIPG--GVVGA-GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLG 664 G +G G G GA G A A AA G VGA G G G +G PG+ G Sbjct: 887 RPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSG-PPGSVGAPGLRGTP 945 Query: 665 GIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGL--------SPIFPGGACLG 716 G K A G G G +G G G+ PG G SP PG Sbjct: 946 GKDGERGEKGAA-GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK 1004 Query: 717 KACGRKR 723 ACG+ R Sbjct: 1005 AACGKVR 1011 Score = 90.9 bits (224), Expect = 4e-18 Identities = 142/486 (29%), Positives = 172/486 (35%), Gaps = 85/486 (17%) Query: 271 AGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAA----AAAAAAKAAKYGAAAGL-VPG 325 AG +G AG G+PG IG I VG P + G L +PG Sbjct: 480 AGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPG 539 Query: 326 GPG--FGPGVVGVPG----AGVPG-VGVPG----AGIPVVPG-AGIPG------------ 361 PG G+ G PG G+PG VG+ G G+P PG G PG Sbjct: 540 PPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRG 599 Query: 362 ----------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGV 411 PG + + A G + VG G P G PG V Sbjct: 600 EKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPP-------GVPGSVVQQ 652 Query: 412 GGIPGVAGVPGVGGVPGVGGVPGV--GISPEAQ----AAAAAKAAKYGVGTPAAAAAKAA 465 G+ G G PG G G G PG I PE + + K +G P Sbjct: 653 EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPG------- 705 Query: 466 AKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGV 524 +PG+ G PGV PG G +PG+ PG PG PG GP G Sbjct: 706 --------IPGLLGLQGPPGPPGVPGPPGPGGSPGL---PGEIGFPGKPGPPGPTGPPGK 754 Query: 525 AAAAKSAAKVAAKAQ--LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA 582 K + R GL G PGL +G GL AG PG AG+PG Sbjct: 755 DGPNGPPGPPGTKGEPGERGEDGL-PGKPGLRGEIGEQGL---AGRPGEKGEAGLPGAPG 810 Query: 583 VPGALA--AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 640 PG + K +PG+ G G G G P G G P + + G Sbjct: 811 FPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAG-PAGPPGL-PGTTSLFTPHPRMPGEQG 868 Query: 641 LVGAAGLGGL-GVGGL-GVPGVGGLGGI--PPAAAAKAAKYGAAGLGGVLGGAGQFPLGG 696 G G GL G GL G PG G G PP A + +GA G G G G G Sbjct: 869 PKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPG 928 Query: 697 VAARPG 702 + PG Sbjct: 929 PSGPPG 934 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 146 bits (368), Expect = 8e-35 Identities = 239/752 (31%), Positives = 279/752 (37%), Gaps = 94/752 (12%) Query: 26 PGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGP---GGKPLKPVPGGLAGAGLGAGLG 80 P G PG IPG G G + +PG GA GP G P P P G+ G GL Sbjct: 666 PPGNPG-IPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQ 724 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGA----GLGGVPGVGGLGVSAGAVVPQPGAGV 136 PG D K GA G G G G AG P PG+ Sbjct: 725 GEKGEKGEDGF-PGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGP-PGSAG 782 Query: 137 KPGKVPGVGLPGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV 192 + GK+ GLPG YPG PG + FPG + P G K PG+ G G PG Sbjct: 783 EKGKLGVPGLPG-YPGR--PGPKGSIGFPGP-LGPIGEKGKSGKTGQPGLEGE-RGPPGS 837 Query: 193 -------GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAG 243 G G P P +G AP +PG GLP G P GP G G G+ G Sbjct: 838 RGERGQPGATGQPGPKGDVGQD-GAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPG 896 Query: 244 YPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTP 301 +P G +G Q A G G + +G G PG PG PG G+ G+ G Sbjct: 897 HPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGP-PGEQGLPGLEGRE 955 Query: 302 AAAAAAAAAAKAAKYGAAAGL-----VPGGPGFGPGVVGVPG-AGVPGV----GVPGAGI 351 A K G A GL GGPG PG G+ G G PG G PG Sbjct: 956 GAKGELGPPGPLGKEGPA-GLRGFPGPKGGPG-DPGPTGLKGDKGPPGPVGANGSPGERG 1013 Query: 352 PVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGV 411 P+ P GI +PG E A K G R G PT G G PG +G Sbjct: 1014 PLGPAGGI---GLPGQSGSEGPVGPAGKKGSRGERGPPG----PT---GKDGIPG-PLGP 1062 Query: 412 GGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQ- 470 G PG AG G G G G PG S + A + G+ PA A AQ Sbjct: 1063 LGPPGAAGPSGEEGDKGDVGAPGHKGS-KGDKGDAGPPGQPGIRGPAGHPGPPGADGAQG 1121 Query: 471 -------FGLVPGVGVAPGVGVA--PGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-G 520 FG GV VGV PG+ PG PG G + G APG G Sbjct: 1122 RRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPG---PPGEKGEVGDVGSMGPHGAPGPRG 1178 Query: 521 PGGVAAAAKSAAKVAAKAQLRAAAGLG----AGIPGLGVGVGVPGL--GVGA-GVPGLGV 573 P G + + Q A G AG PG G+PG +G G G Sbjct: 1179 PQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSG 1238 Query: 574 GAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI---------PGGVVGAGPA 624 AG PG PG AK + +PG LG G G GI PG V G GP Sbjct: 1239 AAGPPGKKGPPGE-DGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPP 1297 Query: 625 AAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGI--PPAAAAKAAKYGAA 680 A+ A + G G G G G G PG G G P A + G Sbjct: 1298 GASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPE 1357 Query: 681 GLGGVLGGAGQFPLGGVAARPGFGLSPIFPGG 712 GL G+ G G+ L G + G P+ P G Sbjct: 1358 GLRGIPGPVGEPGLLGAPGQMG-PPGPLGPSG 1388 Score = 133 bits (334), Expect = 7e-31 Identities = 226/761 (29%), Positives = 268/761 (35%), Gaps = 127/761 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGL-- 79 P P G+ G P G PG V G +G GA G G P P G G GL Sbjct: 510 PQGPRGLQG--PHGPPGRV-------GKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPG 560 Query: 80 -----GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGA 134 G F V PG PG D + G G PG GL G+ P Sbjct: 561 EKGQRGDFGHVGQPGP--PG--EDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRP 616 Query: 135 GVK-----PGKVPGVGLPGVYPGGVLPGAR-------FPGVGVLPGVPTGAGVKPKAPGV 182 GV PG VG PG PG PG + PG L G P G P PG+ Sbjct: 617 GVTGIDGAPGAKGNVGPPGE-PGP--PGQQGNHGSQGLPGPQGLIGTPGEKG-PPGNPGI 672 Query: 183 GGAFAGIPGV-GPFGGPQPGVPLGY------PIKA--PKLPGGYGLPYTTGK-------- 225 G+PG GP G P P G P A P PG G+ T+G Sbjct: 673 ----PGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKG 728 Query: 226 ------LPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVG 278 P G G+ G GK G P G GP+ A +A + G+AG +G Sbjct: 729 EKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLG 788 Query: 279 GAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG 338 G+PG PG PG G +G P K+ K G GP G G PG Sbjct: 789 VPGLPGYPGR-PGPKG--SIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPG 845 Query: 339 A-GVPG----VGVPGAGIPVVPG-AGIPG----AAVPGVVSPEAAAKAAAKAAKYGARPG 388 A G PG VG GA P +PG G+PG PG P + G R Sbjct: 846 ATGQPGPKGDVGQDGA--PGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGE 903 Query: 389 VGVGGIPTYGVGAGGF--PGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAA 446 +G G T G G P G G G G PG G PG G+PG+ Sbjct: 904 LGFQG-QTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGL---------EG 953 Query: 447 AKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPG----VGVAPGVGVAPGVGLAPGVG 502 + AK +G P + A F PG PG G+ G VG G Sbjct: 954 REGAKGELGPPGPLGKEGPAGLRGF---PGPKGGPGDPGPTGLKGDKGPPGPVGANGSPG 1010 Query: 503 VAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPG 561 +G A G+G+ G G A K ++ + G GIPG +G PG Sbjct: 1011 ERGPLGPAGGIGLP---GQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPG 1067 Query: 562 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGA 621 +G G G PG K +K G G G G GI G Sbjct: 1068 AAGPSGEEGDKGDVGAPGH----------KGSK------GDKGDAGPPGQPGIRGPAGHP 1111 Query: 622 GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAG 681 GP A A FG G G+ G VG +G PG+ GL G PP + G+ G Sbjct: 1112 GPPGADGAQGRRGPPGLFGQKGDDGVRGF-VGVIGPPGLQGLPG-PPGEKGEVGDVGSMG 1169 Query: 682 LGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRK 722 G G G G PG PGG A G K Sbjct: 1170 PHGAPGPRGPQGPTGSEGTPG------LPGGVGQPGAVGEK 1204 Score = 132 bits (331), Expect = 1e-30 Identities = 224/751 (29%), Positives = 265/751 (35%), Gaps = 127/751 (16%) Query: 28 GVPGAIPG-----GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 GVPG +PG G G + +PG LG +G G GK +P G G G Sbjct: 788 GVPG-LPGYPGRPGPKGSIGFPGP-LGPIG--EKGKSGKTGQPGLEGERGPPGSRGERGQ 843 Query: 83 PAVTF-PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG--------------------- 120 P T PG G D A K GL G PG G Sbjct: 844 PGATGQPGPKGDVG-QDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRG 902 Query: 121 -LGVSAGAVVPQPGAGVKP-GKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK-- 176 LG P P + P GK VG G PG PG LPG+ G K Sbjct: 903 ELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGP--PGEQGLPGLEGREGAKGE 960 Query: 177 --PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGY--------PIKAPKLPG---------G 216 P P AG+ G GP GGP P G P+ A PG G Sbjct: 961 LGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGG 1020 Query: 217 YGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG----------VGPQAAAAAAAKAAAKF 266 GLP +G GP G G+ G+ G P TG +GP AA + + K Sbjct: 1021 IGLPGQSGS-EGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKG 1079 Query: 267 GAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPG 325 GA G G G G PG PGI G AG G P A A +G G Sbjct: 1080 DVGAPGHKGSKGDKGDAGPPGQ-PGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGD--DG 1136 Query: 326 GPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYG 384 GF GV+G PG G+PG + V G GA PG P+ G Sbjct: 1137 VRGF-VGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGA--PGPRGPQ------------G 1181 Query: 385 ARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAA 444 G G+P G G PG VG G G AG PG G PG+ G G I + + Sbjct: 1182 PTGSEGTPGLP----GGVGQPG-AVGEKGERGDAGDPGPPGAPGIPGPKG-DIGEKGDSG 1235 Query: 445 AAAKAAKYGV-GTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGV 503 + A G G P AK + +PG PG G+ +PG PG Sbjct: 1236 PSGAAGPPGKKGPPGEDGAKGSVGPTG---LPGDLGPPGDPGVSGIDGSPGEKGDPGDVG 1292 Query: 504 APGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPG 561 PG PG PG GP G + + + + A G G PG +G G Sbjct: 1293 GPG---PPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARG 1349 Query: 562 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGA 621 G GL G+PG PG L A PG +G G LG G+PG Sbjct: 1350 PPGRVGPEGL---RGIPGPVGEPGLLGA----------PGQMGPPGPLGPSGLPGLKGDT 1396 Query: 622 GPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GV-------GGLGVPG-VGGLGGI-PPAAA 671 GP G G G GL GV G G PG +G LG PP A Sbjct: 1397 GPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVA 1456 Query: 672 AKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 + G+ G G +G G G PG Sbjct: 1457 GPLGQKGSKGSPGSMGPRGDTGPAGPPGPPG 1487 Score = 131 bits (329), Expect = 3e-30 Identities = 193/631 (30%), Positives = 228/631 (36%), Gaps = 72/631 (11%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAG 78 HP + G G G P GV P G +G G GP G P P GL G L Sbjct: 897 HPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPG--LEGR 954 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGAGV 136 GA + PG L G A + K G G G G+ G G V PG Sbjct: 955 EGAKGELGPPGPLGKEGPA-GLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERG 1013 Query: 137 KPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPF 195 G G+GLPG G+ P V P G+ + PG G GIPG +GP Sbjct: 1014 PLGPAGGIGLPGQ------SGSEGP---VGPAGKKGSRGERGPPGPTGK-DGIPGPLGPL 1063 Query: 196 GGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQ 253 G P P G + PG G G GP G G G AG+P GP Sbjct: 1064 GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDA----GPPGQPGIRGPAGHP-----GPP 1114 Query: 254 AAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGVGTPAAAAAAAAAA 311 A A + G G+ G GV G G I PG+ G+ G P Sbjct: 1115 GADGAQGRR------GPPGLFGQKGDDGVRGFVGVIGPPGLQGLPG--PPGEKGEVGDVG 1166 Query: 312 KAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPG-VGVPG----AGIPVVPGA-GIPGA-- 362 +GA P GP G G+PG G PG VG G AG P PGA GIPG Sbjct: 1167 SMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKG 1226 Query: 363 --AVPGVVSPEAAAKAAAKAA---KYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGV 417 G P AA K + GA+ VG G+P +G G PG G+ G PG Sbjct: 1227 DIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPG-DLGPPGDPGVS-GIDGSPGE 1284 Query: 418 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 477 G PG G PG G G P A + +G K A PG Sbjct: 1285 KGDPGDVGGPGPPGASG---EPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGR 1341 Query: 478 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAA 536 G PG G+ PG PG+ APG PG +GP G+ Sbjct: 1342 TGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGE 1401 Query: 537 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 596 K + G+ GL +G PG G GL G PG PG + + Sbjct: 1402 KGHI--------GLIGL---IGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHP 1450 Query: 597 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAA 627 PGV G LG G G PG + G A Sbjct: 1451 GP-PGVAGPLGQKGSKGSPGSMGPRGDTGPA 1480 Score = 122 bits (307), Expect = 9e-28 Identities = 208/721 (28%), Positives = 247/721 (34%), Gaps = 96/721 (13%) Query: 43 YPGAG-LGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAA 101 +PGAG GA G A+ G+ + PG G+ G FPG P G A Sbjct: 369 FPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPA---- 424 Query: 102 AYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG-KVPGVGLPGVYPGGVLPGARF 160 GL G+PG+ G+ G V+ P K P V VL + Sbjct: 425 ---------GLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQL 475 Query: 161 -----PGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIK--APKL 213 PG L G P G+ P PG+ G GP G P P G K P Sbjct: 476 SMKGPPGPVGLTGRPGPVGL-PGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGA 534 Query: 214 PGGYGLPYTTGK--------LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAK 265 G GLP TG LP G G G G G P G + A + Sbjct: 535 DGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQ 594 Query: 266 FG-AGAAGVLPGVGGAGVPGVPGAIPGIGGIAG----VGTPAAAAAAAAAAKAAKYG--A 318 G G G+L G G G PG + GI G G VG P G Sbjct: 595 AGEPGPRGLLGPRGSPGPTGRPG-VTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPG 653 Query: 319 AAGLV--PG--GPGFGPGVVGVPGAGVPGVGVPGAGIPV-VPGA-GIPGAA-VPGVVSPE 371 GL+ PG GP PG+ G+PG+ P +G PG P GA G PG+A PG P Sbjct: 654 PQGLIGTPGEKGPPGNPGIPGLPGSDGP-LGHPGHEGPTGEKGAQGPPGSAGPPGYPGPR 712 Query: 372 AAAKAAAKAAKYGARPGVGVGGIPTY--------GVGAGGFPG--------------FGV 409 + G + G G P + G G PG Sbjct: 713 GVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQA 772 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPG-------VGISPEAQAAAAAKAAKYGVGTPAAAAA 462 G G PG AG G GVPG+ G PG +G P K G P Sbjct: 773 GEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGF-PGPLGPIGEKGKSGKTGQPGLEGE 831 Query: 463 KAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGP 521 + + PG PG G APG+ PG PG+ PG PG GP Sbjct: 832 RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGI---PGEKGLPGLQGPPGF---PGPKGP 885 Query: 522 GGVAAAAKSAAKVAAKAQLRAAAGLG----AGIPGLGVGVGVPGLGVGAGVPGLGVGAGV 577 G + +L G AG+ G G G G PG G Sbjct: 886 PGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPG---PPGP 942 Query: 578 PGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 637 PG +PG L + AK PG LG G G G PG G G Sbjct: 943 PGEQGLPG-LEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPG 1001 Query: 638 QFGLVGAAG-LGGLG-VGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAG-QFPL 694 G G+ G G LG GG+G+PG G G P A K G G G G G PL Sbjct: 1002 PVGANGSPGERGPLGPAGGIGLPGQSGSEG-PVGPAGKKGSRGERGPPGPTGKDGIPGPL 1060 Query: 695 G 695 G Sbjct: 1061 G 1061 Score = 118 bits (295), Expect = 2e-26 Identities = 169/544 (31%), Positives = 203/544 (37%), Gaps = 80/544 (14%) Query: 28 GVPGAI-PGGVPG--GVFYPGAGLGALGG----GALGPGGKP----LKPVPGGLAGAGLG 76 G PG + G PG G P G+G G G +GP GK + PG G+ Sbjct: 998 GPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIP 1057 Query: 77 AGLGAFPAVTFPGALVPGGVAD-----AAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ 131 LG PGA P G A +K +K G G PG G+ AG P Sbjct: 1058 GPLGPLGP---PGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGP- 1113 Query: 132 PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG 191 PGA G+ G PG++ G R VGV+ P G P PG G + Sbjct: 1114 PGADGAQGRR---GPPGLFGQKGDDGVR-GFVGVIG--PPGLQGLPGPPGEKGEVGDVGS 1167 Query: 192 VGPFGGPQPGVPLGYPIK--APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 +GP G P P P G P LPGG G P G G G AG G P G Sbjct: 1168 MGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAV-------GEKGERGDAGDPGPPGAPG 1220 Query: 250 V-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAA 308 + GP+ K +G +G G G PG GA G + G P Sbjct: 1221 IPGPKG------DIGEKGDSGPSGAAGPPGKKGPPGEDGAK---GSVGPTGLPGDLGP-- 1269 Query: 309 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPG-VGVPGAGIPVVPGA-GIPGA-AV 364 PG PG G+ G PG G PG VG PG PGA G PGA Sbjct: 1270 ---------------PGDPGVS-GIDGSPGEKGDPGDVGGPGP-----PGASGEPGAPGP 1308 Query: 365 PGVVSPEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPGF--GVGVGGIPGVAGV 420 PG P + + GA+ G G P T +GA G PG G+ GIPG G Sbjct: 1309 PGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGE 1368 Query: 421 PGVGGVPGVGGVPG-VGIS--PEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGV 477 PG+ G PG G PG +G S P + K K +G A +PGV Sbjct: 1369 PGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGV 1428 Query: 478 GVAPGVGVAPG-VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAA 536 PG PG G +G GVA +G G +GP G A A Sbjct: 1429 QGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGA 1488 Query: 537 KAQL 540 A+L Sbjct: 1489 PAEL 1492 Score = 84.0 bits (206), Expect = 5e-16 Identities = 151/532 (28%), Positives = 180/532 (33%), Gaps = 88/532 (16%) Query: 236 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-------- 287 AG G G P G Q A G GV+ G G PG PG Sbjct: 372 AGEKGAKGEPAVIEKGQQFEGPPGAP-------GPQGVVGPSGPPGPPGFPGDPGPPGPA 424 Query: 288 AIPGIGGIAGV--------------------GTPAAAAAAAAAAKAAKYGAAAGLVPGGP 327 +PGI GI G+ G P + A A A + + PG Sbjct: 425 GLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPV 484 Query: 328 GF--GPGVVGVPGAGVPGV-GVPGAGIPVVPGAGIPGAAVP----GVVSPEAAAKAAAKA 380 G PG VG+PG PG+ G GA P P G+ G P G + A A Sbjct: 485 GLTGRPGPVGLPGH--PGLKGEEGAEGPQGP-RGLQGPHGPPGRVGKMGRPGADGARGLP 541 Query: 381 AKYGARPGVGVGGIP----------TYG-VGAGGFPG-----FGVGVGGIPGVAGVPGVG 424 G + G G+P +G VG G PG G G G AG PG Sbjct: 542 GDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPR 601 Query: 425 GVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAK-------AAAKAAQFGLV--P 475 G+ G G PG P A AK VG P + GL+ P Sbjct: 602 GLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTP 661 Query: 476 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA---PGVGVAPGI-GPGGVAAAAKSA 531 G PG PG+ + G PG G A PG PG GP GV + + Sbjct: 662 GEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNR 721 Query: 532 AKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAK 591 K + G PG VG+ G G PG G G G A + Sbjct: 722 GLQGEKGEKGE-----DGFPGFKGDVGLKG---DQGKPGAPGPRGEDGPEGPKG--QAGQ 771 Query: 592 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG 651 A + G PG G G LG G+PG GP + + G G G GL Sbjct: 772 AGEEGP--PGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGL- 828 Query: 652 VGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF 703 G G PG G G P A K G G G G G+ L G+ PGF Sbjct: 829 EGERGPPGSRGERGQPGATGQPGPK-GDVGQDGAPGIPGEKGLPGLQGPPGF 879 Score = 68.9 bits (167), Expect = 2e-11 Identities = 102/374 (27%), Positives = 129/374 (34%), Gaps = 79/374 (21%) Query: 353 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGV 411 + PGAG GA P V+ E + G + VG G P G GFPG Sbjct: 368 IFPGAGEKGAKGEPAVI--EKGQQFEGPPGAPGPQGVVGPSGPP----GPPGFPGDP--- 418 Query: 412 GGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAA---AAAKAAAKA 468 G PG AG+PG+ G+ G+ G PG I Q A + G P + A A+A + Sbjct: 419 -GPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFK-----GPPVSFQQAQAQAVLQQ 472 Query: 469 AQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAA 528 Q + G G+ PG VG+ G+ G GP G+ Sbjct: 473 TQLSMKGPPGPV-GLTGRPG-----------PVGLPGHPGLKGEEGAEGPQGPRGLQGP- 519 Query: 529 KSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA 588 G PG +G PG G+PG G GF +PG Sbjct: 520 -------------------HGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPG--- 557 Query: 589 AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLG 648 +PG G G G VG PG G A +A + G G G Sbjct: 558 ----------LPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPR 607 Query: 649 GLGVGGLGVPGVGGLGGIP-----------PAAAAKAAKYGAAGLGGVLGGAGQFPLGGV 697 G G G PGV G+ G P P + +G+ GL G G G G Sbjct: 608 G-SPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGP 666 Query: 698 AARPGFGLSPIFPG 711 PG P PG Sbjct: 667 PGNPGI---PGLPG 677 Score = 66.2 bits (160), Expect = 1e-10 Identities = 102/329 (31%), Positives = 115/329 (34%), Gaps = 68/329 (20%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALG--GGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P P G G G+PGGV PGA +G G G A PG +PG G G Sbjct: 1179 PQGPTGSEGT--PGLPGGVGQPGA-VGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSG 1235 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG--GVPGVGGLGVSAGAVVPQPGAGVKP 138 A PG P G A + LG G PGV G+ S PG P Sbjct: 1236 PSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGS-------PGEKGDP 1288 Query: 139 GKVPGVGLPGVY--PGGV-LPGARFP-------------GVGVLPGV--------PTGAG 174 G V G G PG PG PG R P G PG P GA Sbjct: 1289 GDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGAR 1348 Query: 175 VKPKAPGVGGAFAGIPGV----------GPFGGPQPGVPLGYP-IKAPKLPGG------- 216 P G G GIPG G G P P P G P +K P G Sbjct: 1349 GPPGRVGPEG-LRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGL 1407 Query: 217 ---YGLPYTTGK-----LPYGYGPGGVAGAAGKAGYPTGT--GVGPQAAAAAAAKAAAKF 266 G P G+ LP GP G G G G P G+ GP A + +K Sbjct: 1408 IGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPG-PIGSLGHPGPPGVAGPLGQKGSKG 1466 Query: 267 GAGAAGVLPGVGGAGVPGVPGAIPGIGGI 295 G+ G G AG PG PGA + G+ Sbjct: 1467 SPGSMGPRGDTGPAGPPGPPGAPAELHGL 1495 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 146 bits (368), Expect = 8e-35 Identities = 184/586 (31%), Positives = 215/586 (36%), Gaps = 150/586 (25%) Query: 131 QPGAGVKPGK--VPGVGLPGVY----PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 184 +PG PG +PG G+PG+ P G PG PG+ +PG P G+ PG G Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGY-PGVGKPGMPGMPGKPGAMGM----PGAKG 179 Query: 185 AFAGIPGVGPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGK 241 +GP G P P P G P P + PGG GLP G P G GP G+ G G Sbjct: 180 EIGQKGEIGPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGL 236 Query: 242 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTP 301 G G G A PGV G PG+ G PG G+ GVG P Sbjct: 237 RGPKGDKGFGMPGA-------------------PGVKGP--PGMHGP-PGPVGLPGVGKP 274 Query: 302 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AG 358 K GA P GP PGV G P G+PG+G PG GIP PG G Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGG 332 Query: 359 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPG 416 +PG+ P PG+G G P G GG PG +G G G Sbjct: 333 KGEQGLPGLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKG 378 Query: 417 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPG 476 G PG+GG PG G+PG+ +G P A F G Sbjct: 379 PIGAPGIGGPPGEPGLPGI---------------PGPMGPPGAIG---------FPGPKG 414 Query: 477 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVA 535 G G PG PG+ PG G PG+ PG IGP G A Sbjct: 415 EGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQ-------- 466 Query: 536 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 595 G+PGL GVPGL G PG+ G G PG Sbjct: 467 ------------KGVPGL---PGVPGLLGPKGEPGI---PGDQGLQGPPG---------- 498 Query: 596 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 655 +PG+ G G +G GIPG + GL G G G+ Sbjct: 499 ---IPGIGGPSGPIGPPGIPG------------------PKGEPGLPGPPGF-----PGI 532 Query: 656 GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 701 G PGV GL G PP G GL G G G P G A P Sbjct: 533 GKPGVAGLHG-PPGKPGALGPQGQPGLPGPPGPPG--PPGPPAVMP 575 Score = 142 bits (358), Expect = 1e-33 Identities = 191/625 (30%), Positives = 228/625 (36%), Gaps = 105/625 (16%) Query: 21 LHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPG------GKPLKPVPGGLAGAG 74 L P P +P IP P G P L A G A+G GK +P + Sbjct: 36 LPPQIPPQMPPQIPQYQPLGQQVPHMPL-AKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQ 94 Query: 75 LGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGA 134 +G AV G +P + G G PG+ G G+ PG Sbjct: 95 PAPRMGK-EAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGI--------PGI 145 Query: 135 GVKPGK--VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV 192 KPG PGVG PG +PG +PG P G+ PG G + Sbjct: 146 KGKPGPQGYPGVGKPG------MPG--------MPGKPGAMGM----PGAKGEIGQKGEI 187 Query: 193 GPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGKAGYPTGTG 249 GP G P P P G P P + PGG GLP G P G GP G+ G G G G Sbjct: 188 GPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGLRGPKGDKG 244 Query: 250 VGPQAAAAAAAKAAAKFGAGAAGVLPGV-GGAGVPGVPGAIPGIGGIAGVGTPAAAAAAA 308 G A PGV G G+ G PG + G+ GVG P Sbjct: 245 FGMPGA-------------------PGVKGPPGMHGPPGPV----GLPGVGKPGVTGFPG 281 Query: 309 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AGIPGAAVP 365 K GA P GP PGV G P G+PG+G PG GIP PG G +P Sbjct: 282 PQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGGKGEQGLP 339 Query: 366 GVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGVAGVPGV 423 G+ P PG+G G P G GG PG +G G G G PG+ Sbjct: 340 GLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKGPIGAPGI 385 Query: 424 GGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGV 483 GG PG G+PG+ P A G G K PG+ PG Sbjct: 386 GGPPGEPGLPGIP-GPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGE-----PGLQGFPGK 439 Query: 484 GVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAA 543 G PG+ PG G GV PG+ PG K + L+ Sbjct: 440 PGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV-PG--LLGPKGEPGIPGDQGLQGP 496 Query: 544 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 603 G+ GI G +G PG+ G PGL G PG G PG A +G PG Sbjct: 497 PGI-PGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK-PGV-----AGLHGP--PGKP 547 Query: 604 GGLGALGGVGIPGGVVGAGPAAAAA 628 G LG G G+PG GP A Sbjct: 548 GALGPQGQPGLPGPPGPPGPPGPPA 572 Score = 129 bits (323), Expect = 1e-29 Identities = 178/588 (30%), Positives = 213/588 (36%), Gaps = 138/588 (23%) Query: 174 GVKPKAPGVGGAFAG-IPGVGPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLP 227 G+KP P + IP P G P +PL A P L G P+ LP Sbjct: 32 GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPH----LP 87 Query: 228 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 287 A GK P P A+ + G PG+ G G+PG+ G Sbjct: 88 QYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKG 147 Query: 288 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG 343 PG G GVG P +PG PG PG +G+PGA G G Sbjct: 148 K-PGPQGYPGVGKPG--------------------MPGMPG-KPGAMGMPGAKGEIGQKG 185 Query: 344 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 399 +G+PG P P G+PG PG P + K G R G+ G P Sbjct: 186 EIGPMGIPGPQGPPGPH-GLPGIGKPG--GPGLPGQPGPK----GDRGPKGLPG-PQGLR 237 Query: 400 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAA 459 G G GFG+ G PGV G PG+ G PG G+PGVG K G P Sbjct: 238 GPKGDKGFGMP--GAPGVKGPPGMHGPPGPVGLPGVG-----------KPGVTGFPGPQG 284 Query: 460 AAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI 519 K A PG G PGV PG+ PG+G PG PG PG Sbjct: 285 PLGKPGA--------PGEPGPQGPIGVPGVQGPPGI---PGIG-KPGQDGIPG---QPGF 329 Query: 520 GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPG 579 PGG G+PGL G+PG+ G PG G G Sbjct: 330 -PGGKGE---------------------QGLPGLPGPPGLPGI----GKPGFPGPKGDRG 363 Query: 580 FGAVPGALA-AAKAAKYGA----------AVPGVLGGLGALGGVGIP-----GGVVG--- 620 G VPGAL + GA +PG+ G +G G +G P GG+VG Sbjct: 364 MGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG 423 Query: 621 -AGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-------------GVGGL-GVPGVGGLGG 665 GP K G VG G+ GL GV GL GVPG+ G G Sbjct: 424 PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKG 483 Query: 666 IP--PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 P P G G+GG G G + G PG P FPG Sbjct: 484 EPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG 531 Score = 108 bits (269), Expect = 2e-23 Identities = 136/410 (33%), Positives = 159/410 (38%), Gaps = 71/410 (17%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGG-----GALGPGGKPLKPVPGGLAGAGL 75 P PG G PG G PG V PG G + G G LG G P +P P G G Sbjct: 248 PGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305 Query: 76 GAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGA 134 G P + PG +PG + K GL G+PG GL P P Sbjct: 306 VQGPPGIPGIGKPGQDGIPG-----QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 360 Query: 135 GVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG--- 191 G VPG P G + GA PG+G PG P G+ P G GA G PG Sbjct: 361 DRGMGGVPGALGPRGEKGPI--GA--PGIGGPPGEPGLPGI-PGPMGPPGAI-GFPGPKG 414 Query: 192 ----VGPFGGPQP-GVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY 244 VGP G P P G P G+P K P G G P G LP GP G AG G G Sbjct: 415 EGGIVGPQGPPGPKGEPGLQGFPGK-PGFLGEVGPPGMRG-LPGPIGPKGEAGQKGVPGL 472 Query: 245 PTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGV 298 P G+ GP+ + G G+ G G PG+PG +PG G G+ Sbjct: 473 PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI 532 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPGAGIPVVP- 355 G P A K PG GP PG+ G PG PG P A +P P Sbjct: 533 GKPGVAGLHGPPGK-----------PGALGPQGQPGLPGPPGP--PGPPGPPAVMPPTPP 579 Query: 356 --GAGIP--GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 401 G +P G + GV P A YGA+ G G P Y + A Sbjct: 580 PQGEYLPDMGLGIDGVKPPHA----------YGAKKGKNGG--PAYEMPA 617 Score = 44.7 bits (104), Expect = 3e-04 Identities = 69/221 (31%), Positives = 80/221 (36%), Gaps = 55/221 (24%) Query: 2 AGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGG 60 AG PGV LL P PG P G+PG G G +G G GP G Sbjct: 464 AGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG----IGGPSGPIGPPGIPGPKG 519 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 +P P P G FP + PG AGL G PG Sbjct: 520 EPGLPGPPG------------FPGIGKPGV-------------------AGLHGPPG--- 545 Query: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGA-GVKPKA 179 GA+ PQ G+ PG G PG P V+P P LP + G GVKP Sbjct: 546 ---KPGALGPQGQPGL-PGPPGPPGPPG--PPAVMPPTPPPQGEYLPDMGLGIDGVKP-- 597 Query: 180 PGVGGAFAGIPGVGPFGGP-------QPGVPLGYPIKAPKL 213 P GA G G + P P P+G P+K KL Sbjct: 598 PHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKL 638 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 146 bits (368), Expect = 8e-35 Identities = 184/586 (31%), Positives = 215/586 (36%), Gaps = 150/586 (25%) Query: 131 QPGAGVKPGK--VPGVGLPGVY----PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 184 +PG PG +PG G+PG+ P G PG PG+ +PG P G+ PG G Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGY-PGVGKPGMPGMPGKPGAMGM----PGAKG 179 Query: 185 AFAGIPGVGPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGK 241 +GP G P P P G P P + PGG GLP G P G GP G+ G G Sbjct: 180 EIGQKGEIGPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGL 236 Query: 242 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTP 301 G G G A PGV G PG+ G PG G+ GVG P Sbjct: 237 RGPKGDKGFGMPGA-------------------PGVKGP--PGMHGP-PGPVGLPGVGKP 274 Query: 302 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AG 358 K GA P GP PGV G P G+PG+G PG GIP PG G Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGG 332 Query: 359 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPG 416 +PG+ P PG+G G P G GG PG +G G G Sbjct: 333 KGEQGLPGLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKG 378 Query: 417 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPG 476 G PG+GG PG G+PG+ +G P A F G Sbjct: 379 PIGAPGIGGPPGEPGLPGI---------------PGPMGPPGAIG---------FPGPKG 414 Query: 477 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVA 535 G G PG PG+ PG G PG+ PG IGP G A Sbjct: 415 EGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQ-------- 466 Query: 536 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 595 G+PGL GVPGL G PG+ G G PG Sbjct: 467 ------------KGVPGL---PGVPGLLGPKGEPGI---PGDQGLQGPPG---------- 498 Query: 596 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 655 +PG+ G G +G GIPG + GL G G G+ Sbjct: 499 ---IPGIGGPSGPIGPPGIPG------------------PKGEPGLPGPPGF-----PGI 532 Query: 656 GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 701 G PGV GL G PP G GL G G G P G A P Sbjct: 533 GKPGVAGLHG-PPGKPGALGPQGQPGLPGPPGPPG--PPGPPAVMP 575 Score = 142 bits (358), Expect = 1e-33 Identities = 191/625 (30%), Positives = 228/625 (36%), Gaps = 105/625 (16%) Query: 21 LHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPG------GKPLKPVPGGLAGAG 74 L P P +P IP P G P L A G A+G GK +P + Sbjct: 36 LPPQIPPQMPPQIPQYQPLGQQVPHMPL-AKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQ 94 Query: 75 LGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGA 134 +G AV G +P + G G PG+ G G+ PG Sbjct: 95 PAPRMGK-EAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGI--------PGI 145 Query: 135 GVKPGK--VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV 192 KPG PGVG PG +PG +PG P G+ PG G + Sbjct: 146 KGKPGPQGYPGVGKPG------MPG--------MPGKPGAMGM----PGAKGEIGQKGEI 187 Query: 193 GPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGKAGYPTGTG 249 GP G P P P G P P + PGG GLP G P G GP G+ G G G G Sbjct: 188 GPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGLRGPKGDKG 244 Query: 250 VGPQAAAAAAAKAAAKFGAGAAGVLPGV-GGAGVPGVPGAIPGIGGIAGVGTPAAAAAAA 308 G A PGV G G+ G PG + G+ GVG P Sbjct: 245 FGMPGA-------------------PGVKGPPGMHGPPGPV----GLPGVGKPGVTGFPG 281 Query: 309 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AGIPGAAVP 365 K GA P GP PGV G P G+PG+G PG GIP PG G +P Sbjct: 282 PQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGGKGEQGLP 339 Query: 366 GVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGVAGVPGV 423 G+ P PG+G G P G GG PG +G G G G PG+ Sbjct: 340 GLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKGPIGAPGI 385 Query: 424 GGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGV 483 GG PG G+PG+ P A G G K PG+ PG Sbjct: 386 GGPPGEPGLPGIP-GPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGE-----PGLQGFPGK 439 Query: 484 GVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAA 543 G PG+ PG G GV PG+ PG K + L+ Sbjct: 440 PGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV-PG--LLGPKGEPGIPGDQGLQGP 496 Query: 544 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 603 G+ GI G +G PG+ G PGL G PG G PG A +G PG Sbjct: 497 PGI-PGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK-PGV-----AGLHGP--PGKP 547 Query: 604 GGLGALGGVGIPGGVVGAGPAAAAA 628 G LG G G+PG GP A Sbjct: 548 GALGPQGQPGLPGPPGPPGPPGPPA 572 Score = 129 bits (323), Expect = 1e-29 Identities = 178/588 (30%), Positives = 213/588 (36%), Gaps = 138/588 (23%) Query: 174 GVKPKAPGVGGAFAG-IPGVGPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLP 227 G+KP P + IP P G P +PL A P L G P+ LP Sbjct: 32 GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPH----LP 87 Query: 228 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 287 A GK P P A+ + G PG+ G G+PG+ G Sbjct: 88 QYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKG 147 Query: 288 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG 343 PG G GVG P +PG PG PG +G+PGA G G Sbjct: 148 K-PGPQGYPGVGKPG--------------------MPGMPG-KPGAMGMPGAKGEIGQKG 185 Query: 344 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 399 +G+PG P P G+PG PG P + K G R G+ G P Sbjct: 186 EIGPMGIPGPQGPPGPH-GLPGIGKPG--GPGLPGQPGPK----GDRGPKGLPG-PQGLR 237 Query: 400 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAA 459 G G GFG+ G PGV G PG+ G PG G+PGVG K G P Sbjct: 238 GPKGDKGFGMP--GAPGVKGPPGMHGPPGPVGLPGVG-----------KPGVTGFPGPQG 284 Query: 460 AAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI 519 K A PG G PGV PG+ PG+G PG PG PG Sbjct: 285 PLGKPGA--------PGEPGPQGPIGVPGVQGPPGI---PGIG-KPGQDGIPG---QPGF 329 Query: 520 GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPG 579 PGG G+PGL G+PG+ G PG G G Sbjct: 330 -PGGKGE---------------------QGLPGLPGPPGLPGI----GKPGFPGPKGDRG 363 Query: 580 FGAVPGALA-AAKAAKYGA----------AVPGVLGGLGALGGVGIP-----GGVVG--- 620 G VPGAL + GA +PG+ G +G G +G P GG+VG Sbjct: 364 MGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG 423 Query: 621 -AGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-------------GVGGL-GVPGVGGLGG 665 GP K G VG G+ GL GV GL GVPG+ G G Sbjct: 424 PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKG 483 Query: 666 IP--PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 P P G G+GG G G + G PG P FPG Sbjct: 484 EPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPG 531 Score = 108 bits (269), Expect = 2e-23 Identities = 136/410 (33%), Positives = 159/410 (38%), Gaps = 71/410 (17%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGG-----GALGPGGKPLKPVPGGLAGAGL 75 P PG G PG G PG V PG G + G G LG G P +P P G G Sbjct: 248 PGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305 Query: 76 GAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGA 134 G P + PG +PG + K GL G+PG GL P P Sbjct: 306 VQGPPGIPGIGKPGQDGIPG-----QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 360 Query: 135 GVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG--- 191 G VPG P G + GA PG+G PG P G+ P G GA G PG Sbjct: 361 DRGMGGVPGALGPRGEKGPI--GA--PGIGGPPGEPGLPGI-PGPMGPPGAI-GFPGPKG 414 Query: 192 ----VGPFGGPQP-GVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY 244 VGP G P P G P G+P K P G G P G LP GP G AG G G Sbjct: 415 EGGIVGPQGPPGPKGEPGLQGFPGK-PGFLGEVGPPGMRG-LPGPIGPKGEAGQKGVPGL 472 Query: 245 PTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGV 298 P G+ GP+ + G G+ G G PG+PG +PG G G+ Sbjct: 473 PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI 532 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPGAGIPVVP- 355 G P A K PG GP PG+ G PG PG P A +P P Sbjct: 533 GKPGVAGLHGPPGK-----------PGALGPQGQPGLPGPPGP--PGPPGPPAVMPPTPP 579 Query: 356 --GAGIP--GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 401 G +P G + GV P A YGA+ G G P Y + A Sbjct: 580 PQGEYLPDMGLGIDGVKPPHA----------YGAKKGKNGG--PAYEMPA 617 Score = 44.7 bits (104), Expect = 3e-04 Identities = 69/221 (31%), Positives = 80/221 (36%), Gaps = 55/221 (24%) Query: 2 AGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGG 60 AG PGV LL P PG P G+PG G G +G G GP G Sbjct: 464 AGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG----IGGPSGPIGPPGIPGPKG 519 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 +P P P G FP + PG AGL G PG Sbjct: 520 EPGLPGPPG------------FPGIGKPGV-------------------AGLHGPPG--- 545 Query: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGA-GVKPKA 179 GA+ PQ G+ PG G PG P V+P P LP + G GVKP Sbjct: 546 ---KPGALGPQGQPGL-PGPPGPPGPPG--PPAVMPPTPPPQGEYLPDMGLGIDGVKP-- 597 Query: 180 PGVGGAFAGIPGVGPFGGP-------QPGVPLGYPIKAPKL 213 P GA G G + P P P+G P+K KL Sbjct: 598 PHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKL 638 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 145 bits (367), Expect = 1e-34 Identities = 232/783 (29%), Positives = 274/783 (34%), Gaps = 138/783 (17%) Query: 25 RPG--GVPGAIPG-GVPGGVFYPGA-------GLGALGG-----GALGPGGKPLKPVPGG 69 +PG G PGA G G+PG PGA GL L G G GP G P P G Sbjct: 587 KPGKRGRPGADGGRGMPGE---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 643 Query: 70 LAGAGLGAGLGAFPAVTFP-GALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV 128 + G G P P G L P G A G G+ GV G G + Sbjct: 644 MRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP----------GQPGMAGVDGPPGPKGNM 693 Query: 129 VPQ--PGAGVKPGKVPGVGLPGVYPGGVL--PGARFP-GVGVLPGVPTGAGVKPKAPGVG 183 PQ PG + G GLPG P G + PG + P G L G+P GA P PG Sbjct: 694 GPQGEPGPPGQQGNPGPQGLPG--PQGPIGPPGEKGPQGKPGLAGLP-GADGPPGHPGKE 750 Query: 184 GAFAGIPGVGPFGGPQPGVPLGYPIKAPK----LPGGYGLPYTTGK-----LPYGYGPGG 234 G +GP P P P+GYP P+ G GL + G+ P G G Sbjct: 751 GQSGEKGALGP---PGPQGPIGYP--GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 805 Query: 235 VAGAAGKAGY--PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 + G G+ G P G GP+ A +G AG +G G+PG PG Sbjct: 806 LKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 864 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP--------------------GFGP- 331 G G P A A A K G P GP G GP Sbjct: 865 GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 924 Query: 332 ------------GVVGVPGAGVPGVGVPGA-GIPVVPG----AGIPGAAVP----GVVSP 370 G VG PG P G PG G+P PG G G P GVV P Sbjct: 925 GPPGERGPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 983 Query: 371 EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--VGVGGIPGVAGVPGVGGVPG 428 + + G R G G P G G PG G G PG G+ G G G Sbjct: 984 QG---PTGETGPIGERGHPGPPGPP----GEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1036 Query: 429 VGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPG 488 + G PG P AQ A K + G P + +A G+ PG PG Sbjct: 1037 LRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG 1096 Query: 489 VGVAPGVGLAPG----VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 544 G APG G A GV VG+ GP G ++ Q + Sbjct: 1097 PAGEKG---APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1153 Query: 545 GLG----AGIPGLGVGVGVPGLGVGAGVPG----LGV-----GAGVPGFGAVPGALAAAK 591 G G PGL VG PG+ G G PG G+ G GF PG + Sbjct: 1154 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1213 Query: 592 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL- 650 PG G G +G +G PG GP A G VG G G Sbjct: 1214 L----PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1269 Query: 651 -GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPI- 708 G G PG G+GG P + + G G G G G G PG P+ Sbjct: 1270 GEAGNPGPPGEAGVGG-PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG----PVG 1324 Query: 709 FPG 711 FPG Sbjct: 1325 FPG 1327 Score = 137 bits (346), Expect = 3e-32 Identities = 260/886 (29%), Positives = 296/886 (33%), Gaps = 246/886 (27%) Query: 23 PSRPGGVPGAI-PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 P P G PG P G PG PGA GP G P K G GA LG G Sbjct: 716 PQGPIGPPGEKGPQGKPGLAGLPGAD---------GPPGHPGKEGQSGEKGA-LGPP-GP 764 Query: 82 FPAVTFPGALVPGGV--ADAAAAYKAAKAGAGLGGVPGV-GGLGVSA-----GAVVPQ-- 131 + +PG P GV AD K +K G G PG G +G+ G + P+ Sbjct: 765 QGPIGYPG---PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGE 821 Query: 132 ---------------PGAGVKPGKVPGVGLPGV--YPG--GVLPGARFPGVGVLPGVPTG 172 PG + G+ +G+PG+ YPG G FPG G Sbjct: 822 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 881 Query: 173 AGVKPKA-----------------------PGVGGAFAGIPGVGPFG--GPQ-PGVPLGY 206 GV K PG G G GP G GPQ P P+G+ Sbjct: 882 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 941 Query: 207 PIKA--PKLPGGYGLPYTTGKL-------------PYGY----GPGGVAGAAGKAGYPTG 247 P P PG GLP G+ P G GP G G G+ G+P Sbjct: 942 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 1001 Query: 248 TGV-GPQAAAAAAAKAAAKFGAGAAGV-----------------LPGV-------GGAGV 282 G G Q AA K AK G G+ LPG GG G Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1061 Query: 283 PGVPGAI--PGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGV--- 333 G PG + PG G AG +G P A + GA P GP GV Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121 Query: 334 VGVPG----AGVPG-------VGVPGA----------GIPVVPG----AGIPG-AAVPGV 367 VG+PG AG PG +G PG G P PG G PG A G Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1181 Query: 368 VSPEAAAKAAAKAAKYGAR-----PG-VGVGGIP--------TYGVGAGGFPG------- 406 P + GAR PG +G+ G+P VG G PG Sbjct: 1182 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1241 Query: 407 -------------------FGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEA--QAA 444 GVG G PG AG PG G GVGG G G EA A Sbjct: 1242 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1301 Query: 445 AAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 504 A AK G P K F PG PG GVG G PG Sbjct: 1302 AGPPGAK---GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1358 Query: 505 PGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG----------AGIPGL 553 PG G PG GP G A A + AK + A G AG PG Sbjct: 1359 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1418 Query: 554 GVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVG 613 G+PG G+PG G PG PG +PG+ G G+ G G Sbjct: 1419 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPG-------------LPGLKGDPGSKGEKG 1465 Query: 614 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGI------- 666 PG + GP G G G GL G G PG G GGI Sbjct: 1466 HPGLIGLIGPP---------------GEQGEKGDRGLP-GTQGSPGAKGDGGIPGPAGPL 1509 Query: 667 -PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 PP G G G G AGQ G+ PG SP PG Sbjct: 1510 GPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPG---SPGPPG 1552 Score = 127 bits (318), Expect = 5e-29 Identities = 201/651 (30%), Positives = 227/651 (34%), Gaps = 83/651 (12%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 HP + G G G PGGV P G G +G G P P P G GL Sbjct: 959 HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--PIGERGHPGPPGPPG--EQGLPGAA 1014 Query: 80 GAFPAVTFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK 137 G A PG P G++ D A + GL G G GL G P PG Sbjct: 1015 GKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP-PGPVGS 1070 Query: 138 PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFG 196 PG+ G G P G LPG PG PG P G P G G AG GV GP G Sbjct: 1071 PGERGSAGTAG--PIG-LPGR--PGPQGPPG-PAGEKGAPGEKGPQGP-AGRDGVQGPVG 1123 Query: 197 GPQPGVPLGYP--------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGT 248 P P P G P I P G G G GP G+ G G G G Sbjct: 1124 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP----GPPGLQGPVGAPGIAGGD 1179 Query: 249 GV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAA 307 G GP+ + + G G +G G+PG PG G + +G P Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1239 Query: 308 AAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVP 365 G P GP PG VG G GV G PG AG P PG AG+ G Sbjct: 1240 GPQGPNGADG------PQGP---PGSVGSVG-GVGEKGEPGEAGNPGPPGEAGVGGPK-- 1287 Query: 366 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGG 425 G + A A GA+ G G P G GFPG G G PG AG GVGG Sbjct: 1288 GERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPVGFPG-DPGPPGEPGPAGQDGVGG 1345 Query: 426 VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAA------KAAAKAAQFGLVPGVGV 479 G G PG P A G P AA A K A A PG Sbjct: 1346 DKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTG 1405 Query: 480 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKA 538 G G G+ PG G+ A G PG +GP G+ K Sbjct: 1406 PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK- 1464 Query: 539 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAA 598 G PGL +G PG G GL G PG AK Sbjct: 1465 ----------GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG-------------AKGDGG 1501 Query: 599 VPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 649 +PG G LG G G+PG GP + A + GL G G G Sbjct: 1502 IPGPAGPLGPPGPPGLPG---PQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549 Score = 115 bits (288), Expect = 1e-25 Identities = 217/773 (28%), Positives = 263/773 (34%), Gaps = 131/773 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G+ G P G+ G PG G GP G+P P GL G G Sbjct: 458 PAGPAGIMG--PPGLQGPTGPPG------DPGDRGPPGRPGLPGADGLPGP---PGTMLM 506 Query: 83 PAVTFPGALVPGGVADAAAAYKAA---KAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 139 + G G A A A +A L G PG GL +PG Sbjct: 507 LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTG-------------RPG 553 Query: 140 KVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP 198 V G G G PG + P GV PG PTG K PG G G+PG G Sbjct: 554 PVGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADGG-RGMPGEPGAKGD 611 Query: 199 Q-----PGVP--LGY-----PIKAPKLPGGYGLPYTTGK-----LPYGYGPGGVAGAAGK 241 + PG+P G+ P P PG G+ G+ LP GP G+ G G Sbjct: 612 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 671 Query: 242 AGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAG- 297 G P G+ G + G G G G+PG G I PG G G Sbjct: 672 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 731 Query: 298 ---VGTPAAAAAAAAAAKAAKYGAAAGLVPGGP----GFGPGVVGVPGA-GVPGV----- 344 G P A K + G L P GP G+ PG GV GA GV G+ Sbjct: 732 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY-PGPRGVKGADGVRGLKGSKG 790 Query: 345 -----GVPG--AGIPVVPGAGIPGAAVP-GVVSPEAAAKAA------AKAAKYGARPGVG 390 G PG + + G G P G PE A + + G + +G Sbjct: 791 EKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLG 850 Query: 391 VGGIPTY-----GVGAGGFPGF--GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 V G+P Y G+ GFPGF G G GVAG PG G G G G + Sbjct: 851 VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 910 Query: 444 AAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPG----VGL-- 497 K G G P + PG PG G+ PG G Sbjct: 911 KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 970 Query: 498 ---APGVGVAPG----VGVAPGVGVAPGIGPGG-------VAAAAKSAAKVAAKAQLRAA 543 PG G G G +G GP G AA K AK Q + Sbjct: 971 KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 1030 Query: 544 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 603 AG+ G G+PG G PGL G G G PG + + PG Sbjct: 1031 KDGPAGLRGFPGERGLPG---AQGAPGLKGGEGPQG---PPGPVGS----------PGER 1074 Query: 604 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGL 663 G G G +G+PG GP A A + G G G+ G +G+PG G Sbjct: 1075 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV----QGPVGLPGPAGP 1130 Query: 664 GGIPPAAAAKA-----AKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 G P K + G+ G G G G L G PG PG Sbjct: 1131 AGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1183 Score = 95.1 bits (235), Expect = 2e-19 Identities = 173/597 (28%), Positives = 205/597 (34%), Gaps = 85/597 (14%) Query: 177 PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK---LPYGYGP 232 P P G PG+ GP G P G P + P LPG GLP G LP+ YG Sbjct: 455 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFRYGG 513 Query: 233 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 G G PT + Q A A A A+ + G PG + Sbjct: 514 DGSKG-------PT---ISAQEAQAQAILQQARIA--------------LRGPPGPMGLT 549 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPGVGVPG 348 G VG P ++ A + G P GP PG G PGA G+P G PG Sbjct: 550 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP--GEPG 607 Query: 349 A-------GIPVVPG-AGIPGAAVP-GVVSPEAAAKAAAKAAKYGAR--PG-VGVGGI-- 394 A G+P +PG G G P G P + + G R PG G G+ Sbjct: 608 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLG 667 Query: 395 PTYGVGAGGFPGFGVGVGGIPGV---AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAK 451 P GA G PG GV G PG G G G PG G PG P Q K Sbjct: 668 PRGTPGAPGQPGM-AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 726 Query: 452 YGVGTPAAAAAKAA-------AKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 504 G P A A K Q G +G PG G GV A GV Sbjct: 727 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG-PPGPQGPIGYPGPRGVKGADGVRGL 785 Query: 505 PGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG----------AGIPGL 553 G G PG G G+ ++ + + G +G G Sbjct: 786 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 845 Query: 554 GVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVG 613 +GVPGL G PG G GF PGA K A+ A PG G G G G Sbjct: 846 KGKLGVPGL---PGYPGRQGPKGSTGFPGFPGA-NGEKGARGVAGKPGPRGQRGPTGPRG 901 Query: 614 IPG--GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA 670 G G G GP + + G G G G G G PG G G+P Sbjct: 902 SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF-PGPKGPPGPPGKDGLPGHP 960 Query: 671 AAKA-----AKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRK 722 + K G G GGV+G G G G P PG L A G++ Sbjct: 961 GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 1017 Score = 92.0 bits (227), Expect = 2e-18 Identities = 160/519 (30%), Positives = 179/519 (34%), Gaps = 119/519 (22%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA----------GL 75 PG G P G PG V PG A G +G G+P P G AG G Sbjct: 1053 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1112 Query: 76 GAGLGAFPAVTFPGALVPGGVAD--------AAAAYKAAKAGAGLGGVPGVGGLGVSAGA 127 G V PG P G K +K G G PG GL GA Sbjct: 1113 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1172 Query: 128 VVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAF 186 PG G+ G G++ GAR FPG P P G P PG G Sbjct: 1173 ----PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG----PPGPIGLQGLPGPPGEKGEN 1224 Query: 187 AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 246 + +GP G P P P G P A G G P + G + G G G G AG G P Sbjct: 1225 GDVGPMGPPGPPGPRGPQG-PNGAD---GPQGPPGSVGSVG-GVGEKGEPGEAGNPGPPG 1279 Query: 247 GTGVG--------------PQAAAAAAAKA-----AAKFGAGAAGV-------------- 273 GVG P AA AK K G G Sbjct: 1280 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1339 Query: 274 LPGVGGA----GVPGVPGAIPGIGGIAGVGTP--------AAAAAAAAAAKAAKYGAAAG 321 GVGG G PG PG PG G AG P AA A K AK A A Sbjct: 1340 QDGVGGDKGEDGDPGQPGP-PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1398 Query: 322 LVPGGPG-FGP-GVVGVPGA----GVPGV----GVPGA----------GIPVVPGA-GIP 360 PG G GP G G PG G+PG G+PGA G P +PG G P Sbjct: 1399 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1458 Query: 361 GA-------AVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTYG--VGAGGFPGF- 407 G+ + G++ P E K PG G GGIP +G G PG Sbjct: 1459 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLP 1518 Query: 408 -------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 439 G G G G G+ G PG G PG I P Sbjct: 1519 GPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1557 Score = 65.5 bits (158), Expect = 2e-10 Identities = 98/335 (29%), Positives = 114/335 (34%), Gaps = 25/335 (7%) Query: 387 PGVGVGGIPTYGVGAG--GFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQ 442 PG+ V G P AG G PG G G PG G PG G+PG G+PG P Sbjct: 448 PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPG---PPGTM 504 Query: 443 AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG 502 + G P +A +A A+A + PG G+ PG PG Sbjct: 505 LMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG---PMGLTGRPGPVGGPGSS 561 Query: 503 VAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL 562 A G PG GP GV K + R A G G+PG G G Sbjct: 562 GAKGESGDPGPQ-----GPRGVQGPPGPTGKPGKRG--RPGADGGRGMPGEPGAKGDRGF 614 Query: 563 GVGAGVPGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG 617 G+PG G G PG + +PG G G LG G PG Sbjct: 615 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 674 Query: 618 VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY 677 G A G G G G G G+PG G G PP K Sbjct: 675 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG-NPGPQGLPGPQGPIG-PPGEKGPQGKP 732 Query: 678 GAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGG 712 G AGL G G G G + G L P P G Sbjct: 733 GLAGLPGADGPPGHPGKEGQSGEKG-ALGPPGPQG 766 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 145 bits (367), Expect = 1e-34 Identities = 232/783 (29%), Positives = 274/783 (34%), Gaps = 138/783 (17%) Query: 25 RPG--GVPGAIPG-GVPGGVFYPGA-------GLGALGG-----GALGPGGKPLKPVPGG 69 +PG G PGA G G+PG PGA GL L G G GP G P P G Sbjct: 536 KPGKRGRPGADGGRGMPGE---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 592 Query: 70 LAGAGLGAGLGAFPAVTFP-GALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV 128 + G G P P G L P G A G G+ GV G G + Sbjct: 593 MRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP----------GQPGMAGVDGPPGPKGNM 642 Query: 129 VPQ--PGAGVKPGKVPGVGLPGVYPGGVL--PGARFP-GVGVLPGVPTGAGVKPKAPGVG 183 PQ PG + G GLPG P G + PG + P G L G+P GA P PG Sbjct: 643 GPQGEPGPPGQQGNPGPQGLPG--PQGPIGPPGEKGPQGKPGLAGLP-GADGPPGHPGKE 699 Query: 184 GAFAGIPGVGPFGGPQPGVPLGYPIKAPK----LPGGYGLPYTTGK-----LPYGYGPGG 234 G +GP P P P+GYP P+ G GL + G+ P G G Sbjct: 700 GQSGEKGALGP---PGPQGPIGYP--GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 754 Query: 235 VAGAAGKAGY--PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 + G G+ G P G GP+ A +G AG +G G+PG PG Sbjct: 755 LKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP--------------------GFGP- 331 G G P A A A K G P GP G GP Sbjct: 814 GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 873 Query: 332 ------------GVVGVPGAGVPGVGVPGA-GIPVVPG----AGIPGAAVP----GVVSP 370 G VG PG P G PG G+P PG G G P GVV P Sbjct: 874 GPPGERGPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 932 Query: 371 EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--VGVGGIPGVAGVPGVGGVPG 428 + + G R G G P G G PG G G PG G+ G G G Sbjct: 933 QG---PTGETGPIGERGHPGPPGPP----GEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 985 Query: 429 VGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPG 488 + G PG P AQ A K + G P + +A G+ PG PG Sbjct: 986 LRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG 1045 Query: 489 VGVAPGVGLAPG----VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 544 G APG G A GV VG+ GP G ++ Q + Sbjct: 1046 PAGEKG---APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1102 Query: 545 GLG----AGIPGLGVGVGVPGLGVGAGVPG----LGV-----GAGVPGFGAVPGALAAAK 591 G G PGL VG PG+ G G PG G+ G GF PG + Sbjct: 1103 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1162 Query: 592 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL- 650 PG G G +G +G PG GP A G VG G G Sbjct: 1163 L----PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1218 Query: 651 -GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPI- 708 G G PG G+GG P + + G G G G G G PG P+ Sbjct: 1219 GEAGNPGPPGEAGVGG-PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG----PVG 1273 Query: 709 FPG 711 FPG Sbjct: 1274 FPG 1276 Score = 137 bits (346), Expect = 3e-32 Identities = 260/886 (29%), Positives = 296/886 (33%), Gaps = 246/886 (27%) Query: 23 PSRPGGVPGAI-PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 P P G PG P G PG PGA GP G P K G GA LG G Sbjct: 665 PQGPIGPPGEKGPQGKPGLAGLPGAD---------GPPGHPGKEGQSGEKGA-LGPP-GP 713 Query: 82 FPAVTFPGALVPGGV--ADAAAAYKAAKAGAGLGGVPGV-GGLGVSA-----GAVVPQ-- 131 + +PG P GV AD K +K G G PG G +G+ G + P+ Sbjct: 714 QGPIGYPG---PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGE 770 Query: 132 ---------------PGAGVKPGKVPGVGLPGV--YPG--GVLPGARFPGVGVLPGVPTG 172 PG + G+ +G+PG+ YPG G FPG G Sbjct: 771 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 830 Query: 173 AGVKPKA-----------------------PGVGGAFAGIPGVGPFG--GPQ-PGVPLGY 206 GV K PG G G GP G GPQ P P+G+ Sbjct: 831 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 890 Query: 207 PIKA--PKLPGGYGLPYTTGKL-------------PYGY----GPGGVAGAAGKAGYPTG 247 P P PG GLP G+ P G GP G G G+ G+P Sbjct: 891 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 950 Query: 248 TGV-GPQAAAAAAAKAAAKFGAGAAGV-----------------LPGV-------GGAGV 282 G G Q AA K AK G G+ LPG GG G Sbjct: 951 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1010 Query: 283 PGVPGAI--PGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGV--- 333 G PG + PG G AG +G P A + GA P GP GV Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070 Query: 334 VGVPG----AGVPG-------VGVPGA----------GIPVVPG----AGIPG-AAVPGV 367 VG+PG AG PG +G PG G P PG G PG A G Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1130 Query: 368 VSPEAAAKAAAKAAKYGAR-----PG-VGVGGIP--------TYGVGAGGFPG------- 406 P + GAR PG +G+ G+P VG G PG Sbjct: 1131 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1190 Query: 407 -------------------FGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEA--QAA 444 GVG G PG AG PG G GVGG G G EA A Sbjct: 1191 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1250 Query: 445 AAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 504 A AK G P K F PG PG GVG G PG Sbjct: 1251 AGPPGAK---GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1307 Query: 505 PGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG----------AGIPGL 553 PG G PG GP G A A + AK + A G AG PG Sbjct: 1308 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367 Query: 554 GVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVG 613 G+PG G+PG G PG PG +PG+ G G+ G G Sbjct: 1368 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPG-------------LPGLKGDPGSKGEKG 1414 Query: 614 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGI------- 666 PG + GP G G G GL G G PG G GGI Sbjct: 1415 HPGLIGLIGPP---------------GEQGEKGDRGLP-GTQGSPGAKGDGGIPGPAGPL 1458 Query: 667 -PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 PP G G G G AGQ G+ PG SP PG Sbjct: 1459 GPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPG---SPGPPG 1501 Score = 127 bits (318), Expect = 5e-29 Identities = 201/651 (30%), Positives = 227/651 (34%), Gaps = 83/651 (12%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 HP + G G G PGGV P G G +G G P P P G GL Sbjct: 908 HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--PIGERGHPGPPGPPG--EQGLPGAA 963 Query: 80 GAFPAVTFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK 137 G A PG P G++ D A + GL G G GL G P PG Sbjct: 964 GKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP-PGPVGS 1019 Query: 138 PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFG 196 PG+ G G P G LPG PG PG P G P G G AG GV GP G Sbjct: 1020 PGERGSAGTAG--PIG-LPGR--PGPQGPPG-PAGEKGAPGEKGPQGP-AGRDGVQGPVG 1072 Query: 197 GPQPGVPLGYP--------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGT 248 P P P G P I P G G G GP G+ G G G G Sbjct: 1073 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP----GPPGLQGPVGAPGIAGGD 1128 Query: 249 GV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAA 307 G GP+ + + G G +G G+PG PG G + +G P Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1188 Query: 308 AAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVP 365 G P GP PG VG G GV G PG AG P PG AG+ G Sbjct: 1189 GPQGPNGADG------PQGP---PGSVGSVG-GVGEKGEPGEAGNPGPPGEAGVGGPK-- 1236 Query: 366 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGG 425 G + A A GA+ G G P G GFPG G G PG AG GVGG Sbjct: 1237 GERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPVGFPG-DPGPPGEPGPAGQDGVGG 1294 Query: 426 VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAA------KAAAKAAQFGLVPGVGV 479 G G PG P A G P AA A K A A PG Sbjct: 1295 DKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTG 1354 Query: 480 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKA 538 G G G+ PG G+ A G PG +GP G+ K Sbjct: 1355 PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK- 1413 Query: 539 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAA 598 G PGL +G PG G GL G PG AK Sbjct: 1414 ----------GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG-------------AKGDGG 1450 Query: 599 VPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 649 +PG G LG G G+PG GP + A + GL G G G Sbjct: 1451 IPGPAGPLGPPGPPGLPG---PQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498 Score = 115 bits (288), Expect = 1e-25 Identities = 217/773 (28%), Positives = 263/773 (34%), Gaps = 131/773 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G+ G P G+ G PG G GP G+P P GL G G Sbjct: 407 PAGPAGIMG--PPGLQGPTGPPG------DPGDRGPPGRPGLPGADGLPGP---PGTMLM 455 Query: 83 PAVTFPGALVPGGVADAAAAYKAA---KAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 139 + G G A A A +A L G PG GL +PG Sbjct: 456 LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTG-------------RPG 502 Query: 140 KVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP 198 V G G G PG + P GV PG PTG K PG G G+PG G Sbjct: 503 PVGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADGG-RGMPGEPGAKGD 560 Query: 199 Q-----PGVP--LGY-----PIKAPKLPGGYGLPYTTGK-----LPYGYGPGGVAGAAGK 241 + PG+P G+ P P PG G+ G+ LP GP G+ G G Sbjct: 561 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 620 Query: 242 AGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAG- 297 G P G+ G + G G G G+PG G I PG G G Sbjct: 621 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 680 Query: 298 ---VGTPAAAAAAAAAAKAAKYGAAAGLVPGGP----GFGPGVVGVPGA-GVPGV----- 344 G P A K + G L P GP G+ PG GV GA GV G+ Sbjct: 681 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY-PGPRGVKGADGVRGLKGSKG 739 Query: 345 -----GVPG--AGIPVVPGAGIPGAAVP-GVVSPEAAAKAA------AKAAKYGARPGVG 390 G PG + + G G P G PE A + + G + +G Sbjct: 740 EKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLG 799 Query: 391 VGGIPTY-----GVGAGGFPGF--GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 V G+P Y G+ GFPGF G G GVAG PG G G G G + Sbjct: 800 VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 859 Query: 444 AAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPG----VGL-- 497 K G G P + PG PG G+ PG G Sbjct: 860 KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 919 Query: 498 ---APGVGVAPG----VGVAPGVGVAPGIGPGG-------VAAAAKSAAKVAAKAQLRAA 543 PG G G G +G GP G AA K AK Q + Sbjct: 920 KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 979 Query: 544 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 603 AG+ G G+PG G PGL G G G PG + + PG Sbjct: 980 KDGPAGLRGFPGERGLPG---AQGAPGLKGGEGPQG---PPGPVGS----------PGER 1023 Query: 604 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGL 663 G G G +G+PG GP A A + G G G+ G +G+PG G Sbjct: 1024 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV----QGPVGLPGPAGP 1079 Query: 664 GGIPPAAAAKA-----AKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 G P K + G+ G G G G L G PG PG Sbjct: 1080 AGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1132 Score = 95.1 bits (235), Expect = 2e-19 Identities = 173/597 (28%), Positives = 205/597 (34%), Gaps = 85/597 (14%) Query: 177 PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK---LPYGYGP 232 P P G PG+ GP G P G P + P LPG GLP G LP+ YG Sbjct: 404 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFRYGG 462 Query: 233 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 G G PT + Q A A A A+ + G PG + Sbjct: 463 DGSKG-------PT---ISAQEAQAQAILQQARIA--------------LRGPPGPMGLT 498 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPGVGVPG 348 G VG P ++ A + G P GP PG G PGA G+P G PG Sbjct: 499 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP--GEPG 556 Query: 349 A-------GIPVVPG-AGIPGAAVP-GVVSPEAAAKAAAKAAKYGAR--PG-VGVGGI-- 394 A G+P +PG G G P G P + + G R PG G G+ Sbjct: 557 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLG 616 Query: 395 PTYGVGAGGFPGFGVGVGGIPGV---AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAK 451 P GA G PG GV G PG G G G PG G PG P Q K Sbjct: 617 PRGTPGAPGQPGM-AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 675 Query: 452 YGVGTPAAAAAKAA-------AKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 504 G P A A K Q G +G PG G GV A GV Sbjct: 676 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG-PPGPQGPIGYPGPRGVKGADGVRGL 734 Query: 505 PGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG----------AGIPGL 553 G G PG G G+ ++ + + G +G G Sbjct: 735 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 794 Query: 554 GVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVG 613 +GVPGL G PG G GF PGA K A+ A PG G G G G Sbjct: 795 KGKLGVPGL---PGYPGRQGPKGSTGFPGFPGA-NGEKGARGVAGKPGPRGQRGPTGPRG 850 Query: 614 IPG--GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA 670 G G G GP + + G G G G G G PG G G+P Sbjct: 851 SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF-PGPKGPPGPPGKDGLPGHP 909 Query: 671 AAKA-----AKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRK 722 + K G G GGV+G G G G P PG L A G++ Sbjct: 910 GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 966 Score = 92.0 bits (227), Expect = 2e-18 Identities = 160/519 (30%), Positives = 179/519 (34%), Gaps = 119/519 (22%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA----------GL 75 PG G P G PG V PG A G +G G+P P G AG G Sbjct: 1002 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1061 Query: 76 GAGLGAFPAVTFPGALVPGGVAD--------AAAAYKAAKAGAGLGGVPGVGGLGVSAGA 127 G V PG P G K +K G G PG GL GA Sbjct: 1062 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1121 Query: 128 VVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAF 186 PG G+ G G++ GAR FPG P P G P PG G Sbjct: 1122 ----PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG----PPGPIGLQGLPGPPGEKGEN 1173 Query: 187 AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 246 + +GP G P P P G P A G G P + G + G G G G AG G P Sbjct: 1174 GDVGPMGPPGPPGPRGPQG-PNGAD---GPQGPPGSVGSVG-GVGEKGEPGEAGNPGPPG 1228 Query: 247 GTGVG--------------PQAAAAAAAKA-----AAKFGAGAAGV-------------- 273 GVG P AA AK K G G Sbjct: 1229 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1288 Query: 274 LPGVGGA----GVPGVPGAIPGIGGIAGVGTP--------AAAAAAAAAAKAAKYGAAAG 321 GVGG G PG PG PG G AG P AA A K AK A A Sbjct: 1289 QDGVGGDKGEDGDPGQPGP-PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1347 Query: 322 LVPGGPG-FGP-GVVGVPGA----GVPGV----GVPGA----------GIPVVPGA-GIP 360 PG G GP G G PG G+PG G+PGA G P +PG G P Sbjct: 1348 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1407 Query: 361 GA-------AVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTYG--VGAGGFPGF- 407 G+ + G++ P E K PG G GGIP +G G PG Sbjct: 1408 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLP 1467 Query: 408 -------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 439 G G G G G+ G PG G PG I P Sbjct: 1468 GPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1506 Score = 65.5 bits (158), Expect = 2e-10 Identities = 98/335 (29%), Positives = 114/335 (34%), Gaps = 25/335 (7%) Query: 387 PGVGVGGIPTYGVGAG--GFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQ 442 PG+ V G P AG G PG G G PG G PG G+PG G+PG P Sbjct: 397 PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPG---PPGTM 453 Query: 443 AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG 502 + G P +A +A A+A + PG G+ PG PG Sbjct: 454 LMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG---PMGLTGRPGPVGGPGSS 510 Query: 503 VAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL 562 A G PG GP GV K + R A G G+PG G G Sbjct: 511 GAKGESGDPGPQ-----GPRGVQGPPGPTGKPGKRG--RPGADGGRGMPGEPGAKGDRGF 563 Query: 563 GVGAGVPGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG 617 G+PG G G PG + +PG G G LG G PG Sbjct: 564 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 623 Query: 618 VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY 677 G A G G G G G G+PG G G PP K Sbjct: 624 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG-NPGPQGLPGPQGPIG-PPGEKGPQGKP 681 Query: 678 GAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGG 712 G AGL G G G G + G L P P G Sbjct: 682 GLAGLPGADGPPGHPGKEGQSGEKG-ALGPPGPQG 715 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 145 bits (367), Expect = 1e-34 Identities = 232/783 (29%), Positives = 274/783 (34%), Gaps = 138/783 (17%) Query: 25 RPG--GVPGAIPG-GVPGGVFYPGA-------GLGALGG-----GALGPGGKPLKPVPGG 69 +PG G PGA G G+PG PGA GL L G G GP G P P G Sbjct: 575 KPGKRGRPGADGGRGMPGE---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 631 Query: 70 LAGAGLGAGLGAFPAVTFP-GALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV 128 + G G P P G L P G A G G+ GV G G + Sbjct: 632 MRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP----------GQPGMAGVDGPPGPKGNM 681 Query: 129 VPQ--PGAGVKPGKVPGVGLPGVYPGGVL--PGARFP-GVGVLPGVPTGAGVKPKAPGVG 183 PQ PG + G GLPG P G + PG + P G L G+P GA P PG Sbjct: 682 GPQGEPGPPGQQGNPGPQGLPG--PQGPIGPPGEKGPQGKPGLAGLP-GADGPPGHPGKE 738 Query: 184 GAFAGIPGVGPFGGPQPGVPLGYPIKAPK----LPGGYGLPYTTGK-----LPYGYGPGG 234 G +GP P P P+GYP P+ G GL + G+ P G G Sbjct: 739 GQSGEKGALGP---PGPQGPIGYP--GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 793 Query: 235 VAGAAGKAGY--PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 + G G+ G P G GP+ A +G AG +G G+PG PG Sbjct: 794 LKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 852 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP--------------------GFGP- 331 G G P A A A K G P GP G GP Sbjct: 853 GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 912 Query: 332 ------------GVVGVPGAGVPGVGVPGA-GIPVVPG----AGIPGAAVP----GVVSP 370 G VG PG P G PG G+P PG G G P GVV P Sbjct: 913 GPPGERGPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 971 Query: 371 EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--VGVGGIPGVAGVPGVGGVPG 428 + + G R G G P G G PG G G PG G+ G G G Sbjct: 972 QG---PTGETGPIGERGHPGPPGPP----GEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1024 Query: 429 VGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPG 488 + G PG P AQ A K + G P + +A G+ PG PG Sbjct: 1025 LRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG 1084 Query: 489 VGVAPGVGLAPG----VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 544 G APG G A GV VG+ GP G ++ Q + Sbjct: 1085 PAGEKG---APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1141 Query: 545 GLG----AGIPGLGVGVGVPGLGVGAGVPG----LGV-----GAGVPGFGAVPGALAAAK 591 G G PGL VG PG+ G G PG G+ G GF PG + Sbjct: 1142 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1201 Query: 592 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL- 650 PG G G +G +G PG GP A G VG G G Sbjct: 1202 L----PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1257 Query: 651 -GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPI- 708 G G PG G+GG P + + G G G G G G PG P+ Sbjct: 1258 GEAGNPGPPGEAGVGG-PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG----PVG 1312 Query: 709 FPG 711 FPG Sbjct: 1313 FPG 1315 Score = 137 bits (346), Expect = 3e-32 Identities = 260/886 (29%), Positives = 296/886 (33%), Gaps = 246/886 (27%) Query: 23 PSRPGGVPGAI-PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 P P G PG P G PG PGA GP G P K G GA LG G Sbjct: 704 PQGPIGPPGEKGPQGKPGLAGLPGAD---------GPPGHPGKEGQSGEKGA-LGPP-GP 752 Query: 82 FPAVTFPGALVPGGV--ADAAAAYKAAKAGAGLGGVPGV-GGLGVSA-----GAVVPQ-- 131 + +PG P GV AD K +K G G PG G +G+ G + P+ Sbjct: 753 QGPIGYPG---PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGE 809 Query: 132 ---------------PGAGVKPGKVPGVGLPGV--YPG--GVLPGARFPGVGVLPGVPTG 172 PG + G+ +G+PG+ YPG G FPG G Sbjct: 810 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 869 Query: 173 AGVKPKA-----------------------PGVGGAFAGIPGVGPFG--GPQ-PGVPLGY 206 GV K PG G G GP G GPQ P P+G+ Sbjct: 870 RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 929 Query: 207 PIKA--PKLPGGYGLPYTTGKL-------------PYGY----GPGGVAGAAGKAGYPTG 247 P P PG GLP G+ P G GP G G G+ G+P Sbjct: 930 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 989 Query: 248 TGV-GPQAAAAAAAKAAAKFGAGAAGV-----------------LPGV-------GGAGV 282 G G Q AA K AK G G+ LPG GG G Sbjct: 990 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1049 Query: 283 PGVPGAI--PGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGV--- 333 G PG + PG G AG +G P A + GA P GP GV Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109 Query: 334 VGVPG----AGVPG-------VGVPGA----------GIPVVPG----AGIPG-AAVPGV 367 VG+PG AG PG +G PG G P PG G PG A G Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1169 Query: 368 VSPEAAAKAAAKAAKYGAR-----PG-VGVGGIP--------TYGVGAGGFPG------- 406 P + GAR PG +G+ G+P VG G PG Sbjct: 1170 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1229 Query: 407 -------------------FGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEA--QAA 444 GVG G PG AG PG G GVGG G G EA A Sbjct: 1230 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1289 Query: 445 AAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 504 A AK G P K F PG PG GVG G PG Sbjct: 1290 AGPPGAK---GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1346 Query: 505 PGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG----------AGIPGL 553 PG G PG GP G A A + AK + A G AG PG Sbjct: 1347 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406 Query: 554 GVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVG 613 G+PG G+PG G PG PG +PG+ G G+ G G Sbjct: 1407 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPG-------------LPGLKGDPGSKGEKG 1453 Query: 614 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGI------- 666 PG + GP G G G GL G G PG G GGI Sbjct: 1454 HPGLIGLIGPP---------------GEQGEKGDRGLP-GTQGSPGAKGDGGIPGPAGPL 1497 Query: 667 -PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 PP G G G G AGQ G+ PG SP PG Sbjct: 1498 GPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPG---SPGPPG 1540 Score = 127 bits (318), Expect = 5e-29 Identities = 201/651 (30%), Positives = 227/651 (34%), Gaps = 83/651 (12%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 HP + G G G PGGV P G G +G G P P P G GL Sbjct: 947 HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--PIGERGHPGPPGPPG--EQGLPGAA 1002 Query: 80 GAFPAVTFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK 137 G A PG P G++ D A + GL G G GL G P PG Sbjct: 1003 GKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP-PGPVGS 1058 Query: 138 PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFG 196 PG+ G G P G LPG PG PG P G P G G AG GV GP G Sbjct: 1059 PGERGSAGTAG--PIG-LPGR--PGPQGPPG-PAGEKGAPGEKGPQGP-AGRDGVQGPVG 1111 Query: 197 GPQPGVPLGYP--------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGT 248 P P P G P I P G G G GP G+ G G G G Sbjct: 1112 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP----GPPGLQGPVGAPGIAGGD 1167 Query: 249 GV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAA 307 G GP+ + + G G +G G+PG PG G + +G P Sbjct: 1168 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1227 Query: 308 AAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVP 365 G P GP PG VG G GV G PG AG P PG AG+ G Sbjct: 1228 GPQGPNGADG------PQGP---PGSVGSVG-GVGEKGEPGEAGNPGPPGEAGVGGPK-- 1275 Query: 366 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGG 425 G + A A GA+ G G P G GFPG G G PG AG GVGG Sbjct: 1276 GERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPVGFPG-DPGPPGEPGPAGQDGVGG 1333 Query: 426 VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAA------KAAAKAAQFGLVPGVGV 479 G G PG P A G P AA A K A A PG Sbjct: 1334 DKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTG 1393 Query: 480 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKA 538 G G G+ PG G+ A G PG +GP G+ K Sbjct: 1394 PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK- 1452 Query: 539 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAA 598 G PGL +G PG G GL G PG AK Sbjct: 1453 ----------GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG-------------AKGDGG 1489 Query: 599 VPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 649 +PG G LG G G+PG GP + A + GL G G G Sbjct: 1490 IPGPAGPLGPPGPPGLPG---PQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537 Score = 115 bits (288), Expect = 1e-25 Identities = 217/773 (28%), Positives = 263/773 (34%), Gaps = 131/773 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G+ G P G+ G PG G GP G+P P GL G G Sbjct: 446 PAGPAGIMG--PPGLQGPTGPPG------DPGDRGPPGRPGLPGADGLPGP---PGTMLM 494 Query: 83 PAVTFPGALVPGGVADAAAAYKAA---KAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 139 + G G A A A +A L G PG GL +PG Sbjct: 495 LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTG-------------RPG 541 Query: 140 KVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP 198 V G G G PG + P GV PG PTG K PG G G+PG G Sbjct: 542 PVGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADGG-RGMPGEPGAKGD 599 Query: 199 Q-----PGVP--LGY-----PIKAPKLPGGYGLPYTTGK-----LPYGYGPGGVAGAAGK 241 + PG+P G+ P P PG G+ G+ LP GP G+ G G Sbjct: 600 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 659 Query: 242 AGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAG- 297 G P G+ G + G G G G+PG G I PG G G Sbjct: 660 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 719 Query: 298 ---VGTPAAAAAAAAAAKAAKYGAAAGLVPGGP----GFGPGVVGVPGA-GVPGV----- 344 G P A K + G L P GP G+ PG GV GA GV G+ Sbjct: 720 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY-PGPRGVKGADGVRGLKGSKG 778 Query: 345 -----GVPG--AGIPVVPGAGIPGAAVP-GVVSPEAAAKAA------AKAAKYGARPGVG 390 G PG + + G G P G PE A + + G + +G Sbjct: 779 EKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLG 838 Query: 391 VGGIPTY-----GVGAGGFPGF--GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 V G+P Y G+ GFPGF G G GVAG PG G G G G + Sbjct: 839 VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 898 Query: 444 AAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPG----VGL-- 497 K G G P + PG PG G+ PG G Sbjct: 899 KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 958 Query: 498 ---APGVGVAPG----VGVAPGVGVAPGIGPGG-------VAAAAKSAAKVAAKAQLRAA 543 PG G G G +G GP G AA K AK Q + Sbjct: 959 KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 1018 Query: 544 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 603 AG+ G G+PG G PGL G G G PG + + PG Sbjct: 1019 KDGPAGLRGFPGERGLPG---AQGAPGLKGGEGPQG---PPGPVGS----------PGER 1062 Query: 604 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGL 663 G G G +G+PG GP A A + G G G+ G +G+PG G Sbjct: 1063 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV----QGPVGLPGPAGP 1118 Query: 664 GGIPPAAAAKA-----AKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 G P K + G+ G G G G L G PG PG Sbjct: 1119 AGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1171 Score = 95.1 bits (235), Expect = 2e-19 Identities = 173/597 (28%), Positives = 205/597 (34%), Gaps = 85/597 (14%) Query: 177 PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK---LPYGYGP 232 P P G PG+ GP G P G P + P LPG GLP G LP+ YG Sbjct: 443 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFRYGG 501 Query: 233 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 G G PT + Q A A A A+ + G PG + Sbjct: 502 DGSKG-------PT---ISAQEAQAQAILQQARIA--------------LRGPPGPMGLT 537 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPGVGVPG 348 G VG P ++ A + G P GP PG G PGA G+P G PG Sbjct: 538 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP--GEPG 595 Query: 349 A-------GIPVVPG-AGIPGAAVP-GVVSPEAAAKAAAKAAKYGAR--PG-VGVGGI-- 394 A G+P +PG G G P G P + + G R PG G G+ Sbjct: 596 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLG 655 Query: 395 PTYGVGAGGFPGFGVGVGGIPGV---AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAK 451 P GA G PG GV G PG G G G PG G PG P Q K Sbjct: 656 PRGTPGAPGQPGM-AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 714 Query: 452 YGVGTPAAAAAKAA-------AKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 504 G P A A K Q G +G PG G GV A GV Sbjct: 715 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG-PPGPQGPIGYPGPRGVKGADGVRGL 773 Query: 505 PGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG----------AGIPGL 553 G G PG G G+ ++ + + G +G G Sbjct: 774 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 833 Query: 554 GVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVG 613 +GVPGL G PG G GF PGA K A+ A PG G G G G Sbjct: 834 KGKLGVPGL---PGYPGRQGPKGSTGFPGFPGA-NGEKGARGVAGKPGPRGQRGPTGPRG 889 Query: 614 IPG--GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA 670 G G G GP + + G G G G G G PG G G+P Sbjct: 890 SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF-PGPKGPPGPPGKDGLPGHP 948 Query: 671 AAKA-----AKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRK 722 + K G G GGV+G G G G P PG L A G++ Sbjct: 949 GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE 1005 Score = 92.0 bits (227), Expect = 2e-18 Identities = 160/519 (30%), Positives = 179/519 (34%), Gaps = 119/519 (22%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA----------GL 75 PG G P G PG V PG A G +G G+P P G AG G Sbjct: 1041 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1100 Query: 76 GAGLGAFPAVTFPGALVPGGVAD--------AAAAYKAAKAGAGLGGVPGVGGLGVSAGA 127 G V PG P G K +K G G PG GL GA Sbjct: 1101 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1160 Query: 128 VVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAF 186 PG G+ G G++ GAR FPG P P G P PG G Sbjct: 1161 ----PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG----PPGPIGLQGLPGPPGEKGEN 1212 Query: 187 AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 246 + +GP G P P P G P A G G P + G + G G G G AG G P Sbjct: 1213 GDVGPMGPPGPPGPRGPQG-PNGAD---GPQGPPGSVGSVG-GVGEKGEPGEAGNPGPPG 1267 Query: 247 GTGVG--------------PQAAAAAAAKA-----AAKFGAGAAGV-------------- 273 GVG P AA AK K G G Sbjct: 1268 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1327 Query: 274 LPGVGGA----GVPGVPGAIPGIGGIAGVGTP--------AAAAAAAAAAKAAKYGAAAG 321 GVGG G PG PG PG G AG P AA A K AK A A Sbjct: 1328 QDGVGGDKGEDGDPGQPGP-PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1386 Query: 322 LVPGGPG-FGP-GVVGVPGA----GVPGV----GVPGA----------GIPVVPGA-GIP 360 PG G GP G G PG G+PG G+PGA G P +PG G P Sbjct: 1387 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1446 Query: 361 GA-------AVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTYG--VGAGGFPGF- 407 G+ + G++ P E K PG G GGIP +G G PG Sbjct: 1447 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLP 1506 Query: 408 -------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 439 G G G G G+ G PG G PG I P Sbjct: 1507 GPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1545 Score = 65.5 bits (158), Expect = 2e-10 Identities = 98/335 (29%), Positives = 114/335 (34%), Gaps = 25/335 (7%) Query: 387 PGVGVGGIPTYGVGAG--GFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQ 442 PG+ V G P AG G PG G G PG G PG G+PG G+PG P Sbjct: 436 PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPG---PPGTM 492 Query: 443 AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG 502 + G P +A +A A+A + PG G+ PG PG Sbjct: 493 LMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG---PMGLTGRPGPVGGPGSS 549 Query: 503 VAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL 562 A G PG GP GV K + R A G G+PG G G Sbjct: 550 GAKGESGDPGPQ-----GPRGVQGPPGPTGKPGKRG--RPGADGGRGMPGEPGAKGDRGF 602 Query: 563 GVGAGVPGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGG 617 G+PG G G PG + +PG G G LG G PG Sbjct: 603 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 662 Query: 618 VVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY 677 G A G G G G G G+PG G G PP K Sbjct: 663 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG-NPGPQGLPGPQGPIG-PPGEKGPQGKP 720 Query: 678 GAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGG 712 G AGL G G G G + G L P P G Sbjct: 721 GLAGLPGADGPPGHPGKEGQSGEKG-ALGPPGPQG 754 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 145 bits (365), Expect = 2e-34 Identities = 221/735 (30%), Positives = 260/735 (35%), Gaps = 115/735 (15%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKP-LKPVPG--GLAGA-GLGAGLGAFP 83 G+PGA PG G + PG G GP G P L+ VPG GL G GL A LG+ P Sbjct: 888 GMPGA-PGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLP 946 Query: 84 AVTFPGALVPGGVADAAAA---YKAAKAGAGLGGVPGVGGLGVSAGAVVP--QPGAGVKP 138 + G A Y K G G+PGV GL A + +P A Sbjct: 947 IEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEAR 1006 Query: 139 GKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFGG 197 G G PG LPG PG+P G + G PG+ G G Sbjct: 1007 GD-NSEGDPGCVGSPGLPGP--------PGLPGQRGEE-----------GPPGMRGSPGP 1046 Query: 198 PQPGVPLGYP--IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAA 255 P P P G+P + +P LPG G TG G G G G+ GYP TG P Sbjct: 1047 PGPIGPPGFPGAVGSPGLPGLQGERGLTGLT----GDKGEPGPPGQPGYPGATG--PPGL 1100 Query: 256 AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAK 315 + AG G G G+PG PG G G + Sbjct: 1101 PGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGF 1160 Query: 316 YGAAAGLVPGGPGFGPGVVGVPGAGVPGV-----GVPG-AGIPVVPGAGIPGAAVPGVVS 369 G PG PGF PG VG PG P G+ G +G+P PG P PG+ Sbjct: 1161 PGP-----PGPPGF-PGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGP----PGIQG 1210 Query: 370 PEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--GIPGVAGVPGVGGVP 427 P K K G R G G P G G PGF G G+PG G G G P Sbjct: 1211 PAGLDGLDGKDGKPGLRGDPGPAGPP----GLMGPPGFKGKTGHPGLPGPKGDCGKPGPP 1266 Query: 428 GVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAP 487 G G PG P A VG P A + GL G G+A Sbjct: 1267 GSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLA- 1325 Query: 488 GVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-------IGPGGVAAAAKSAAKVAAKAQL 540 G+ PG PG PG A G PG GP G AA + K Sbjct: 1326 GLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKG-- 1383 Query: 541 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA------------ 588 RA G G G VG PG G PG +G PG VPG++ Sbjct: 1384 RAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFI 1443 Query: 589 --------AAKAAKYG---------AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAK 631 + A Y AA PG G G G G PG P + + Sbjct: 1444 RQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPG-----APGSPGLPGQ 1498 Query: 632 AAAKAAQFGLVGAAGLGGL----GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLG 687 + Q GL G GL G G G+G+ G GL G PP YG G G +G Sbjct: 1499 IGREGRQ-GLPGVRGLPGTKGEKGDIGIGIAGENGLPG-PPGPQGPPG-YGKMGATGPMG 1555 Query: 688 GAGQFPLGGVAARPG 702 G + G+ PG Sbjct: 1556 QQG---IPGIPGPPG 1567 Score = 143 bits (360), Expect = 6e-34 Identities = 223/743 (30%), Positives = 269/743 (36%), Gaps = 153/743 (20%) Query: 89 GALVPGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSAG--AVVPQPGAGVKPGKVPGV 144 GAL P G+ + K K G+ GVPG G G V+ G PG V Sbjct: 384 GALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPE 443 Query: 145 GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFGGP-QPGV 202 GL G LPG PG+G LPG P G P G G+ +GIPG GP G P +PGV Sbjct: 444 GLAGEPGPPGLPGP--PGIG-LPGTPGDPGGPPGPKGDKGS-SGIPGKEGPGGKPGKPGV 499 Query: 203 P--LGYPIKA-PKLPGGY----GLPYTTGKLPYGY--------GPGGVAGAAGKAGYPTG 247 G P + P LP G+ GLP G P G G G+ G G+ G P Sbjct: 500 KGEKGDPCEVCPTLPEGFQNFVGLPGKPG--PKGEPGDPVPARGDPGIQGIKGEKGEPCL 557 Query: 248 TGVGPQAAAAAAAKAAAKFGAGAAGV-LPGVGG-AGVPGVPGAIPGIGGIAGVGTPAAAA 305 + A + A G+ G LPG+ G AGVPG+ G G G+P Sbjct: 558 SCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPG 617 Query: 306 AAAAAAKAAKYG-------AAAGLV------------------PGGPGFG---------- 330 A G A + L PG PGFG Sbjct: 618 PVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGE 677 Query: 331 ------------------PGVVGVPG-AGVPGVGVPGA----------GIPVVPGAGIPG 361 PG G PG +G PGV P P + G Sbjct: 678 RGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDM 737 Query: 362 AAVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTY-GV-GAGGFPGFGV-GVGGIP 415 A PG P E + + K G +PG+ GV G P GV G G PG GV G G P Sbjct: 738 AGRPGQPGPKGEQGPEGVGRPGKPG-QPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEP 796 Query: 416 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 475 G G+PG+ G+PG G PG AQ + K A VG P A+ + + Q G Sbjct: 797 GAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQT- 855 Query: 476 GVGVAPGVGVAPGVGVAPGVGLAPGVG--VAPGVGVAPGVGVAPGIGPGGVAAAAKSAAK 533 G+ PG G PG P G + G+ APG+ + PG Sbjct: 856 GLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGP------- 908 Query: 534 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL------ 587 GIPG GVPGL GVPG G PG A G+L Sbjct: 909 --------------PGIPGPPGPPGVPGL---QGVPGNNGLPGQPGLTAELGSLPIEQHL 951 Query: 588 ---AAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAA---------AAAAAKAAAK 635 + A PG L G G GIP GV G A A A+ Sbjct: 952 LKSICGDCVQGQRAHPGYLVEKGEKGDQGIP-GVPGLDNCAQCFLSLERPRAEEARGDNS 1010 Query: 636 AAQFGLVGAAGL-GGLGVGGL----GVPGVGGLGGIPPAAAAKA--AKYGAAGLGGVLGG 688 G VG+ GL G G+ G G PG+ G G P G+ GL G+ G Sbjct: 1011 EGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGE 1070 Query: 689 AGQFPLGGVAARPGFGLSPIFPG 711 G L G PG P +PG Sbjct: 1071 RGLTGLTGDKGEPGPPGQPGYPG 1093 Score = 124 bits (312), Expect = 2e-28 Identities = 231/823 (28%), Positives = 279/823 (33%), Gaps = 155/823 (18%) Query: 17 LLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLG 76 L+S S G PG G+PG PG G GP G P P P G AG Sbjct: 568 LVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGA 627 Query: 77 AGLGAFPAVTF-------------------------PGALVPGGVADAAA-AYKAAKAGA 110 G P PG +PG A K K A Sbjct: 628 KGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDA 687 Query: 111 GLGGVPGVGGL----GVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVL 166 G G PG G G+S V P AG K K G G V A PG Sbjct: 688 GNPGDPGTPGTTGRPGLSGEPGVQGP-AGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGP 746 Query: 167 PGVPTGAGV----KPKAPGVGGAFA--GIPGV-GPFGGPQPGV--PLGYPIKAPKLPGGY 217 G GV KP PG+ G G+ GV G G P GV P G P AP LPG Sbjct: 747 KGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEP-GAPGLPGIQ 805 Query: 218 GLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAA--AKAAAKFGAGAAGVL 274 GLP G GP G GA G G TG VGP A+ + + + G G Sbjct: 806 GLPGPRGPP----GPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTP 861 Query: 275 PGVGGAGVPGVPG--AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLV--PGGPGFG 330 G G G PG + P G + G P A ++ G+ PG PG Sbjct: 862 GEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGV- 920 Query: 331 PGVVGVPG----AGVPGVGVPGAGIPVV------------------PG----------AG 358 PG+ GVPG G PG+ +P+ PG G Sbjct: 921 PGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQG 980 Query: 359 IPGAAVPGV-------VSPEAAAKAAAKAAKYGARPG-VGVGGIP--------------- 395 IPG VPG+ +S E A+ PG VG G+P Sbjct: 981 IPG--VPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPP 1038 Query: 396 --------TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAA 447 +G GFPG VG G+PG+ G G+ G+ G G PG P A Sbjct: 1039 GMRGSPGPPGPIGPPGFPG-AVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGP 1097 Query: 448 KAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGV 507 G P + +A PG + G+ PG G G G Sbjct: 1098 P------GLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGD 1151 Query: 508 GVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGVG 565 G PG GP G S +A+ + G +G+PG G PG+ Sbjct: 1152 QGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGP 1211 Query: 566 AGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-----GVVG 620 AG+ GL G PG PG A PG++G G G G PG G G Sbjct: 1212 AGLDGLDGKDGKPGLRGDPGP----------AGPPGLMGPPGFKGKTGHPGLPGPKGDCG 1261 Query: 621 A-GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGA 679 GP + A + G G G G VG G PG G GI A Sbjct: 1262 KPGPPGSTGRPGAEGEPGAMGPQGRPGPPG-HVGPPGPPGQPGPAGI-----------SA 1309 Query: 680 AGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRK 722 GL G G G+ L G+ +PG P PG A G++ Sbjct: 1310 VGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKE 1352 Score = 99.0 bits (245), Expect = 1e-20 Identities = 143/452 (31%), Positives = 174/452 (38%), Gaps = 77/452 (17%) Query: 25 RPG--GVPGAIPGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGL 79 +PG G PG P G PG V PG G A G G GP G P P P G G AGL Sbjct: 1157 QPGFPGPPG--PPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGL 1214 Query: 80 GAFPAVTF-------PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQP 132 PG P G+ +K GL G G G G+ +P Sbjct: 1215 DGLDGKDGKPGLRGDPGPAGPPGLM-GPPGFKGKTGHPGLPGPKGDCGKPGPPGST-GRP 1272 Query: 133 GAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG-------- 184 GA +PG + G PG PG V P PG PG P AG+ A G+ G Sbjct: 1273 GAEGEPGAMGPQGRPGP-PGHVGP----PGP---PGQPGPAGIS--AVGLKGDRGATGER 1322 Query: 185 AFAGIPGV-GPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLPYGYGPGGVAGA 238 AG+PG GP G P P G A P G YG P G P G G AG Sbjct: 1323 GLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGD-PGAAGQKGQAGE 1381 Query: 239 AGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAG 297 G+AG P G G A + G A PG G+ G+PGVPG++ + Sbjct: 1382 KGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGA---PGPSGSPGLPGVPGSMGDMVNYDE 1438 Query: 298 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA-GIPVVP 355 + + Y + P PG G PG G PG PGA G P +P Sbjct: 1439 IKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGR--PGAPGSPGLP 1496 Query: 356 GA-------GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV----GAGG 403 G G+PG +PG G + +G+G G+ G G Sbjct: 1497 GQIGREGRQGLPGVRGLPGTK---------------GEKGDIGIGIAGENGLPGPPGPQG 1541 Query: 404 FPGFG-VGVGGIPGVAGVPGVGGVPGVGGVPG 434 PG+G +G G G G+PG+ G PG G PG Sbjct: 1542 PPGYGKMGATGPMGQQGIPGIPGPPGPMGQPG 1573 Score = 97.1 bits (240), Expect = 5e-20 Identities = 162/585 (27%), Positives = 196/585 (33%), Gaps = 129/585 (22%) Query: 231 GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIP 290 G G +GA G +G P TG Q K G G+ G G G PG I Sbjct: 378 GEKGESGALGPSGLPGSTGEKGQ-----------KGEKGDGGIKGVPGKPGRDGRPGEIC 426 Query: 291 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG-PGVVGVPG----------- 338 IG G P A + G +PG PG G PG G PG Sbjct: 427 VIGPKGQKGDPGFVGPEGLAGEPGPPG-----LPGPPGIGLPGTPGDPGGPPGPKGDKGS 481 Query: 339 AGVPGVGVPG-----------------------------AGIPVVPG-AGIPGAAVPGVV 368 +G+PG PG G+P PG G PG VP Sbjct: 482 SGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARG 541 Query: 369 SP-------EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVP 421 P E + ++ GA+ V G G G PGF G+ G+PG AGVP Sbjct: 542 DPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTG----ASGDVGSPGF--GLPGLPGRAGVP 595 Query: 422 GVGGVPGVGGVPGVGISPEAQ---AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVG 478 G+ G G G G SP A K AK P A + + +PG Sbjct: 596 GLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPS 655 Query: 479 VAPGVGVAPGVGVAPGVGLA--------------PGVGVAPGVGVAPGVGVAPGI-GPGG 523 G PG G+ G A PG PG PG+ PG+ GP G Sbjct: 656 GEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAG 715 Query: 524 VAAAAKSAAKVAAKAQLRAAAGLGAGIPGL----------GVG----VGVPGLGVGAGVP 569 + A L+ AG PG GVG G PGL G P Sbjct: 716 --PKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPP 773 Query: 570 GL-GV-------GAGVPGFGAVPGA--LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV 619 GL GV G GV G PGA L + PG G GA G G+ G Sbjct: 774 GLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATG 833 Query: 620 GAGPAAAAAAAKAA--AKAAQFGLVGAAGLGGLGVGGLGVPG-----------VGGLGGI 666 GP A+ + + Q GL G G G G G PG G+ G Sbjct: 834 PVGPPGASVSGPPGRDGQQGQTGLRGTPGEKG-PRGEKGEPGECSCPSQGDLIFSGMPGA 892 Query: 667 PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 P + + G G G+ G G + G+ PG P PG Sbjct: 893 PGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPG 937 Score = 61.6 bits (148), Expect = 2e-09 Identities = 109/399 (27%), Positives = 140/399 (35%), Gaps = 75/399 (18%) Query: 322 LVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVV--SPEAAAKAAAK 379 L P GP G G G+PG PG+ G GA V SP+A + A Sbjct: 330 LAPSGPKGGKGERGLPGP-------PGS-------KGEKGARGNDCVRISPDAPLQCAE- 374 Query: 380 AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 439 G + G G +G G+PG G G G G GG+ GV P Sbjct: 375 ----GPKGEKGESG--------------ALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKP 416 Query: 440 EAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAP 499 G K F G+ PG PG+ PG+GL P Sbjct: 417 GRDGRP---------GEICVIGPKGQKGDPGFVGPEGLAGEPG---PPGLPGPPGIGL-P 463 Query: 500 GVGVAPGVGVAP-----GVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP-GL 553 G PG P G+ GPGG K K + + +P G Sbjct: 464 GTPGDPGGPPGPKGDKGSSGIPGKEGPGG------KPGKPGVKGEKGDPCEVCPTLPEGF 517 Query: 554 GVGVGVPGLGVGAGVPGLGVGA----GVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGAL 609 VG+PG G PG V A G+ G G + ++ GA ++ GA Sbjct: 518 QNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGA--QHLVSSTGAS 575 Query: 610 GGVGIPG-GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP- 667 G VG PG G+ G A K + FG G AG G G +G G+ G G P Sbjct: 576 GDVGSPGFGLPGLPGRAGVPGLK--GEKGNFGEAGPAGSPG-PPGPVGPAGIKGAKGEPC 632 Query: 668 -PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGL 705 P A + G + + G +G+ G PGFGL Sbjct: 633 EPCPALSNLQDGDVRVVALPGPSGE---KGEPGPPGFGL 668 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 143 bits (360), Expect = 6e-34 Identities = 217/714 (30%), Positives = 259/714 (36%), Gaps = 120/714 (16%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLG 80 +P PG A P G PG + P G +GG G GP G P P G G +GL Sbjct: 2151 NPGLPGERGMAGPEGKPG-LQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP---SGLK 2206 Query: 81 AFPAVTFPGALVPG-GVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 139 P T P PG G+ A GL G PG GL V PQ G+ PG Sbjct: 2207 GEPGETGP----PGRGLTGPTGA-------VGLPGPPGPSGL------VGPQGSPGL-PG 2248 Query: 140 KVPGVGLPGVYPG-----GVLPGARFPGVGVLPGVPTGAGVK--PKAPGVGG-AFAGIPG 191 +V G PG PG G PGV PG+P G K P G G A G+PG Sbjct: 2249 QVGETGKPGA-PGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPG 2307 Query: 192 VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVG 251 G PG G + P G GLP GP G G AG+AG P G Sbjct: 2308 AKGEKGA-PGGLAGDLVGEPGAKGDRGLP----------GPRGEKGEAGRAGEPGDPGED 2356 Query: 252 PQAAAAAAAKAAAKFGAGAAGVL-----PGV-GGAGVPGVPGAIPGIGGIAG-------V 298 Q A G G G PGV G G+PG+PGA PG+ G G + Sbjct: 2357 GQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGA-PGVVGFPGQTGPRGEM 2415 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-------GVPGVGVPGA-- 349 G P + A + G L P GP PG VG PGA G PGVG+PG Sbjct: 2416 GQPGPSGERGLAGPPGREGIPGPLGPPGP---PGSVGPPGASGLKGDKGDPGVGLPGPRG 2472 Query: 350 --GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF 407 G P + G PG P + G + VG G+ G G Sbjct: 2473 ERGEPGIRGED----GRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLK-------GDKGD 2521 Query: 408 GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAK 467 + G PG G G G G G+ G K + G P +K Sbjct: 2522 SAVILGPPGPRGAKGDMGERGPRGLDG------------DKGPRGDNGDPGDKGSKGEPG 2569 Query: 468 AAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGV-GVAPGVGVAPGIGPGGVAA 526 +PG+ G PG PG +PG PG+ G VG +GP G+ Sbjct: 2570 DKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGF---MGPRGLKG 2626 Query: 527 AAKSAAKVAAKAQLRAAAGLGA--GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVP 584 + ++ A GL G G G PGL AG G GVPG P Sbjct: 2627 ----------ERGVKGACGLDGEKGDKGEAGPPGRPGL---AGHKGEMGEPGVPGQSGAP 2673 Query: 585 G--ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLV 642 G L K + PG G G G G PG GP+ +A G Sbjct: 2674 GKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPR 2733 Query: 643 GAAGLGGLGVGGLGVPG--VGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPL 694 G GL G G G PG V G G+ P A + + G G G G G+ L Sbjct: 2734 GPEGLQG-QKGERGPPGERVVGAPGV-PGAPGERGEQGRPGPAGPRGEKGEAAL 2785 Score = 142 bits (357), Expect = 1e-33 Identities = 232/770 (30%), Positives = 279/770 (36%), Gaps = 140/770 (18%) Query: 26 PGGVPG--AIPG--GVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLG 80 P G PG + G G PG PG LG G G G G+P KP GL G G G Sbjct: 1995 PIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEA 2054 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK 140 P K + G G PG+ G PG PG Sbjct: 2055 GRPGER------------GERGEKGERGEQGRDGPPGLPGT----------PGPPGPPGP 2092 Query: 141 VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFA--GIPGV-GPFGG 197 V PG PG L G + P PG+ GA +P + G G G+PG+ G G Sbjct: 2093 KVSVDEPG--PG--LSGEQGP-----PGLK-GAKGEPGSNGDQGPKGDRGVPGIKGDRGE 2142 Query: 198 PQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV----G 251 P P G P LPG G+ GK L GP G G G G P G+ G Sbjct: 2143 PGPRGQDGNP----GLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198 Query: 252 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--------AIPGIGGIAG-VGTPA 302 PQ + + + G G+ G G+PG PG PG+ G G G P Sbjct: 2199 PQGPSGLKGEPG-ETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPG 2257 Query: 303 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG---VGVPGA-GIPVV 354 A A+ K G+ VPG PG PG VG G G PG VG+PGA G Sbjct: 2258 APGRDGASGKDGDRGSPG--VPGSPGL-PGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGA 2314 Query: 355 PG------AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF 407 PG G PGA G+ P A +A + G G G P G GF G Sbjct: 2315 PGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAP----GPKGFKGD 2370 Query: 408 -GVGVGGIPGVAGVPGVG---GVPGVGGVPGV--------------GISPEAQAAAAAKA 449 GVGV G PG G PGV G+PG+ G PGV P + A Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP 2430 Query: 450 AKYGV-------GTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG 502 + G+ G P + A+ PGVG+ PG G G PG Sbjct: 2431 GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGL-PGPRGERGEPGIRGEDGRPGQE 2489 Query: 503 VAPGVGVAPGV----GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAG-LGA--------- 548 G+ PG G +G G+ +A + R A G +G Sbjct: 2490 GPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGD 2549 Query: 549 -------GIPGLGVGVGVPGLGVGAGVPGL-GV--GAGVPGFGAVPGALAAAKAAKYGAA 598 G PG G PG AG+PGL G+ G PG +PG K G Sbjct: 2550 KGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPG--DPGSPGKDG-- 2605 Query: 599 VPGVLGGLGALGGVGIPGGVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGV 657 VPG+ G G +G +G P G+ G G A + G G GL G G +G Sbjct: 2606 VPGIRGEKGDVGFMG-PRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAG-HKGEMGE 2663 Query: 658 PGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSP 707 PGV G G P K G G G G G G PG G P Sbjct: 2664 PGVPGQSGAPGKEGLIGPK-GDRGFDGQPGPKGDQGEKGERGTPGIGGFP 2712 Score = 134 bits (338), Expect = 2e-31 Identities = 210/730 (28%), Positives = 244/730 (33%), Gaps = 128/730 (17%) Query: 26 PGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFP 83 P G PG +PG G PG PG+ G G G+P P G G GL P Sbjct: 1270 PPGDPG-LPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSP 1328 Query: 84 AVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPG--VGGLGVSAGAVVPQPGAGVKPGKV 141 +PG D + + G G PG +GG G PG PG Sbjct: 1329 G-------LPGPRGDPGE--RGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPR 1379 Query: 142 PGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK-PKAPGVGGAFAGIPGV-GPFGGPQ 199 +G PG LPG + G G + P PG GG G PG+ G G P Sbjct: 1380 GPLGDPGPRGPPGLPGT------AMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG 1433 Query: 200 PGVPLGYPIK----------APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 P P+G P K AP LPG G P G GP G G G G+P G Sbjct: 1434 PQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGP----RGPPGAIGPKGDRGFPGPLG 1489 Query: 250 -------------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG----AIPGI 292 G + A + AK G G G G PG PG P + Sbjct: 1490 EAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAV 1549 Query: 293 GGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG-------FGP----GVVGVPG-A 339 G G G A A + G ++PG PG GP G G PG + Sbjct: 1550 AGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDS 1609 Query: 340 GVPG----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP 395 G PG G PG PV P G P KA + G R GV G P Sbjct: 1610 GPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRG-P 1668 Query: 396 TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVG 455 G G PG G G PG +G G G PG G PG + A + G Sbjct: 1669 VGEKGDQGDPGED-GRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQE 1727 Query: 456 TPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV-GVA--------PG 506 P PG+ APG G PG PGV G A PG Sbjct: 1728 GPRGPKGD-----------PGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPG 1776 Query: 507 VGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG 565 + G+ PG GP G AA A G+PGL G+PG Sbjct: 1777 LDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRD-----------GLPGLRGEQGLPGPSGP 1825 Query: 566 AGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAA 625 G+PG G PG G PG G G G G G GP Sbjct: 1826 PGLPGKPGEDGKPGLNGKNGE----------PGDPGEDGRKGEKGDSGASGREGRDGPKG 1875 Query: 626 AAAAAKAAAKAAQFGLVGAAGLGGL----GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAG 681 A G++G G GL G G G PGV G G P + G G Sbjct: 1876 ERGAP---------GILGPQGPPGLPGPVGPPGQGFPGVPG-GTGPKGDRGETGSKGEQG 1925 Query: 682 LGGVLGGAGQ 691 L G G G+ Sbjct: 1926 LPGERGLRGE 1935 Score = 128 bits (322), Expect = 2e-29 Identities = 227/799 (28%), Positives = 273/799 (34%), Gaps = 139/799 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-------GALGPGGKPLKPVPGGLAGAGL 75 P G PG P G PG + G G G G GP G P GL GA Sbjct: 1692 PKGDRGEPG--PPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDP------GLPGAPG 1743 Query: 76 GAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAG 135 G+ F PG GV A K + GL G G+ G +AG P AG Sbjct: 1744 ERGIEGFRGP--PGPQGDPGVRGPAGE-KGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAG 1800 Query: 136 VK--PGK--VPGV----GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFA 187 PG+ +PG+ GLPG LPG PG PG+ G +P PG G Sbjct: 1801 KAGDPGRDGLPGLRGEQGLPGPSGPPGLPGK--PGEDGKPGL-NGKNGEPGDPGEDGRKG 1857 Query: 188 --------------------GIPGV-GPFGGPQPGVPLGYPIKA-PKLPGGYGLPYTTGK 225 G PG+ GP G P P+G P + P +PGG G G+ Sbjct: 1858 EKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGE 1917 Query: 226 LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAA------KFGAGAAGVLP---- 275 G G+ G G G P + A KA+A + + LP Sbjct: 1918 TG-SKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPER 1976 Query: 276 ------GVGGAGVPGVPGAI--PGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGG 326 G G PG G I PG G+ G G P A +GL G Sbjct: 1977 RRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLA-GE 2035 Query: 327 PGFGPGVVGVPG--AGVPGVGVPGA----------------GIPVVPGA-GIPGAAVPGV 367 PG PG+ G+PG GV G PG G P +PG G PG P V Sbjct: 2036 PG-KPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKV 2094 Query: 368 VSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGG 425 E + + G + G G G G PG G G PG G G G Sbjct: 2095 SVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIK-GDRGEPGPRGQDGNPG 2153 Query: 426 VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGV 485 +PG G+ G P Q G G P A A A G+ PG Sbjct: 2154 LPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETG 2213 Query: 486 APGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAK----VAAKAQLR 541 PG G+ G A G+ PG G +PG+ PG V K A + K R Sbjct: 2214 PPGRGLTGPTG-AVGLPGPPGPSGLVGPQGSPGL-PGQVGETGKPGAPGRDGASGKDGDR 2271 Query: 542 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF-------GAVPGALAAAKAAK 594 + G+ G PGL VG G G PG V G+PG G + G L AK Sbjct: 2272 GSPGV-PGSPGLPGPVGPKGEPGPTGAPGQAV-VGLPGAKGEKGAPGGLAGDLVGEPGAK 2329 Query: 595 YGAAVPGVLGGLGALG--------------------------GVGIPGGVVGAGPAAAAA 628 +PG G G G GVG+PG GP Sbjct: 2330 GDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKG 2389 Query: 629 AAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGI--PPAAAAKAAKYGAAGLGGVL 686 G+VG G G G +G PG G G+ PP G G G + Sbjct: 2390 DLGLPGLPGAPGVVGFPGQTGPR-GEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSV 2448 Query: 687 GGAGQFPLGGVAARPGFGL 705 G G L G PG GL Sbjct: 2449 GPPGASGLKGDKGDPGVGL 2467 Score = 120 bits (302), Expect = 3e-27 Identities = 202/689 (29%), Positives = 238/689 (34%), Gaps = 133/689 (19%) Query: 111 GLGGVPGVGGLGVSAGAVVPQ--------------PGAGVKPGKVPGVGLPGVYPG--GV 154 G G PG GL GA PQ PGA +PG G PG PG G+ Sbjct: 1266 GQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGT-PGAPGL 1324 Query: 155 LPGARFPGVGVLPGV--PTGAGVKPKAPG--VGGAFAGIPG----VGPFGGPQPGVPLGY 206 PG PG P G +P APG +GG G+PG GP G P P PLG Sbjct: 1325 KGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGD 1384 Query: 207 PIKAPKLPGGYGLPYTTGKL---------PYGYGPGGVA-GAAGKAGYPTGTGVGPQAAA 256 P P+ P G LP T K P G G GG+A G G G P G PQ Sbjct: 1385 P--GPRGPPG--LPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG--PQGPV 1438 Query: 257 AAAAKAAAKFGA--GAAGVLPG----------------VGGAGVPGVPGAIPGIGGIAGV 298 K K + GA G LPG +G G G PG + G Sbjct: 1439 GPPGKKGEKGDSEDGAPG-LPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGER 1497 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAG 358 G P A + A + GA P GP G G PG G P V G Sbjct: 1498 GPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGR---------PGDPAVVGPA 1548 Query: 359 IPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG----FGV-GVG 412 + G G V P A + G PG+ + G P G G PG G+ G Sbjct: 1549 VAGPKGEKGDVGPAGPRGATGVQGERGP-PGLVLPGDP----GPKGDPGDRGPIGLTGRA 1603 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFG 472 G PG +G PG G PG G PG + P + + G KA + Sbjct: 1604 GPPGDSGPPGEKGDPGRPGPPG-PVGPRGRDGEVGEKGDEGPPGDPGLPGKAGER----- 1657 Query: 473 LVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSA 531 G+ APGV G G G +PG G PG GP G Sbjct: 1658 ---GLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPG 1714 Query: 532 AKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAK 591 A+ G PG G G G+PG G+ GF PG Sbjct: 1715 AR-------------EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGP-QGDP 1760 Query: 592 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL- 650 + A G G G G G+ G AGP+ AA A + GL G G GL Sbjct: 1761 GVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLP 1820 Query: 651 ---GVGGL-------GVPGVGGLGGIP--PAAAAKAAKYGAAGLG--------------- 683 G GL G PG+ G G P P + + G +G Sbjct: 1821 GPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAP 1880 Query: 684 GVLGGAGQFPLGGVAARPGFGLSPIFPGG 712 G+LG G L G PG G P PGG Sbjct: 1881 GILGPQGPPGLPGPVGPPGQGF-PGVPGG 1908 Score = 118 bits (296), Expect = 2e-26 Identities = 199/723 (27%), Positives = 249/723 (34%), Gaps = 131/723 (18%) Query: 28 GVPGAI-PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG P G G PG G+ GP G +P P G G + G Sbjct: 1661 GAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTG-------- 1712 Query: 87 FPGALVPGGVADAAA-AYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK--PGKVPG 143 PGA G D + K GL G PG G+ G PQ GV+ G+ Sbjct: 1713 -PGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGD 1771 Query: 144 VGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFGGPQPGV 202 G PG+ L G PG P P GA K PG G +PG+ G G P P Sbjct: 1772 RGPPGLDGRSGLDGK--PGAAG-PSGPNGAAGKAGDPGRDG----LPGLRGEQGLPGPSG 1824 Query: 203 PLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-------VGPQAA 255 P G P K PG G P G GK G P G G A Sbjct: 1825 PPGLPGK----PGEDGKP----------------GLNGKNGEPGDPGEDGRKGEKGDSGA 1864 Query: 256 AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAK 315 + + K GA G+L G G PG+PG + G G G P + Sbjct: 1865 SGREGRDGPKGERGAPGIL---GPQGPPGLPGPV----GPPGQGFPGVPGGTGPKGDRGE 1917 Query: 316 YGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVS------ 369 G+ G PG G+ G PG+ VP V ++ AGI +A+ +V Sbjct: 1918 TGSKG--EQGLPG-ERGLRGEPGS-VPNVD------RLLETAGIKASALREIVETWDESS 1967 Query: 370 ------PEAAAKAAAKAAKYGARPGVGVGGIP--------TYGVGAGGFPGFGVGVGGIP 415 PE + + G G G P G G PG +G G P Sbjct: 1968 GSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPP 2027 Query: 416 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 475 G +G+ G G PG+ G+PG +A +A + G + + Sbjct: 2028 GPSGLAGEPGKPGIPGLPG-------RAGGVGEAGRPGERGERGEKGERGEQ-------- 2072 Query: 476 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 535 G PG+ PG PG P V V PG G++ GP G+ A Sbjct: 2073 GRDGPPGLPGTPGPPGPPG----PKVSVD-----EPGPGLSGEQGPPGLKGAKGEPGSNG 2123 Query: 536 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 595 + G+PG+ G PG G PGL G+ G PG Sbjct: 2124 DQGPKG-----DRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGP------ 2172 Query: 596 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 655 PG +GG G G G PG AGPA + + + G G G G GL Sbjct: 2173 -RGPPGPVGGHGDPGPPGAPG---LAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGL 2228 Query: 656 -GVPGVGGLGGIP-----PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIF 709 G PG GL G P + K GA G G G G GV PG P+ Sbjct: 2229 PGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLP-GPVG 2287 Query: 710 PGG 712 P G Sbjct: 2288 PKG 2290 Score = 102 bits (253), Expect = 2e-21 Identities = 151/504 (29%), Positives = 174/504 (34%), Gaps = 76/504 (15%) Query: 227 PYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV 285 P G G G G G P TG GPQ +A + GA G G AG PG Sbjct: 1259 PGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGT 1318 Query: 286 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG-PGVVGVPG-AGVPG 343 PGA PG+ G G+ P A G V GG G G PG G PG +G PG Sbjct: 1319 PGA-PGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPG 1377 Query: 344 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 399 +G PG P G+PG A+ G PG G GGI Sbjct: 1378 PRGPLGDPGPRGP----PGLPGTAMKGDKGDRGER----------GPPGPGEGGIAPGEP 1423 Query: 400 GAGGFPGF----------------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 G G PG G G PG+ G PG G G G PG I P+ Sbjct: 1424 GLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPG-AIGPKGDR 1482 Query: 444 AAAAKAAKYGV----GTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAP 499 + G G P A ++ +PGV PG A G PG Sbjct: 1483 GFPGPLGEAGEKGERGPPGPAGSRG---------LPGVAGRPG---AKGPEGPPGPTGRQ 1530 Query: 500 GVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVG 558 G PG P V V P + GP G A A G +PG G Sbjct: 1531 GEKGEPGRPGDPAV-VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKG 1589 Query: 559 VPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGV 618 PG G GL AG PG PG PG G G +G G G V Sbjct: 1590 DPG---DRGPIGLTGRAGPPGDSGPPGE----------KGDPGRPGPPGPVGPRGRDGEV 1636 Query: 619 VGAGPAAAAAAAKAAAKAAQFGLVGAAGL-GGLG-VGGLGVPGVGGLGGIPPAAAAKAAK 676 G KA + GL GA G+ G +G G G PG G G P ++ K Sbjct: 1637 GEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPK--- 1693 Query: 677 YGAAGLGGVLGGAGQFPLGGVAAR 700 G G G G G+ G AR Sbjct: 1694 -GDRGEPGPPGPPGRLVDTGPGAR 1716 Score = 66.6 bits (161), Expect = 8e-11 Identities = 94/314 (29%), Positives = 112/314 (35%), Gaps = 23/314 (7%) Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAA 469 G G PG G+ G G PG G+PG +P Q + AK G P A + A Sbjct: 1254 GQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRA 1313 Query: 470 QFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV--GVAPGIGPG--GVA 525 PG APG+ +PG+ PG PG G PG V G GPG G Sbjct: 1314 G---NPGTPGAPGLKGSPGL---PGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRK 1367 Query: 526 AAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVP 584 + + L G G+PG + G G G PG G G PG +P Sbjct: 1368 GDPGPSGPPGPRGPLGDPGPRGPPGLPGTAM-KGDKGDRGERGPPGPGEGGIAPGEPGLP 1426 Query: 585 GALAAAKAAKYGAAVPGVLGGLGAL--GGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLV 642 G L + + PG G G G G+PG G A G Sbjct: 1427 G-LPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFP 1485 Query: 643 GAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 702 G G G G G PG G G+P A AK G G G G G+ G RPG Sbjct: 1486 GPLGEAG-EKGERGPPGPAGSRGLPGVAGRPGAK-GPEGPPGPTGRQGE---KGEPGRPG 1540 Query: 703 FGLSPIFPGGACLG 716 P G A G Sbjct: 1541 ---DPAVVGPAVAG 1551 >gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] Length = 703 Score = 142 bits (359), Expect = 8e-34 Identities = 203/668 (30%), Positives = 244/668 (36%), Gaps = 122/668 (18%) Query: 52 GGGALGPGG----KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAK 107 GGGA G G K ++P+ G G G G + + P L+P + K Sbjct: 29 GGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLP--LLPMDL----------K 76 Query: 108 AGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY----PGGVLPGARFPGV 163 G G PG G PG PGK PG+G PG++ P G PG G Sbjct: 77 GEPGPPGKPGPRG----------PPGPPGFPGK-PGMGKPGLHGQPGPAGP-PGFSRMGK 124 Query: 164 GVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQ--PGVPLGYPIKAPKLPGGYGLPY 221 PG+P G P PG+ G GI G GP PG+P I P PG G+P Sbjct: 125 AGPPGLPGKVG-PPGQPGLRGE-PGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVP- 181 Query: 222 TTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAG 281 GP G G G G P GP G G G LPG G G Sbjct: 182 ---------GPPGFQGEPGPQGEP-----GPPGDRGLKGDN----GVGQPG-LPGAPGQG 222 Query: 282 VPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-G 340 G PG PG+ G AG+G P A + G VPG G PG VG G G Sbjct: 223 --GAPGP-PGLPGPAGLGKPGLDGLPGAPGDKGESGPPG--VPGPRG-EPGAVGPKGPPG 276 Query: 341 VPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP--TYG 398 V GVGVPGA AG+PG P E + G G+ G+P Sbjct: 277 VDGVGVPGA-------AGLPGPQGPSGAKGEPGTRGPPGLI---GPTGYGMPGLPGPKGD 326 Query: 399 VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPA 458 G G PG +G G PG G PG G G+GG PG+ +A + G P Sbjct: 327 RGPAGVPGL-LGDRGEPGEDGEPGEQGPQGLGGPPGL-------PGSAGLPGRRGPPGPK 378 Query: 459 AAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 518 A G G PGV G G+ PGV PG PG PG Sbjct: 379 GEA--------------GPGGPPGVPGIRGDQGPSGLAGKPGV---PGERGLPGAHGPPG 421 Query: 519 -IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAG 576 GP G L LG G PGL G+PGL AG G G Sbjct: 422 PTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPG 481 Query: 577 VPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVG-AGPAAAAAAAKAA 633 + G +PG +A + G A G G G+PG G+ G GP A Sbjct: 482 LKGEPGLPGPPGEGRAGEPGTA--------GPTGPPGVPGSPGITGPPGPPGPPGPPGAP 533 Query: 634 AKAAQFGLVGAAGLGGLGVGGLGVPG-VGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQF 692 G G+ GL + GV G V G GG P + + + VL F Sbjct: 534 ------GAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVL--TSPF 585 Query: 693 PLGGVAAR 700 P G+ + Sbjct: 586 PASGMPVK 593 Score = 126 bits (317), Expect = 6e-29 Identities = 160/470 (34%), Positives = 185/470 (39%), Gaps = 82/470 (17%) Query: 23 PSRPG-GVPGAIPGGVPGGVFYPG-AGLGALGG----GALGPGGKP-LKPVPG-----GL 70 P +PG G PG G PG PG + +G G G +GP G+P L+ PG GL Sbjct: 97 PGKPGMGKPGL--HGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGL 154 Query: 71 AGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVP 130 G GL +T PG GV ++ G G PG GL G V Sbjct: 155 RGPPGPPGLPGPSGITIPGKPGAQGVP-GPPGFQGEPGPQGEPGPPGDRGLKGDNG--VG 211 Query: 131 QPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAG---------------- 174 QPG PG+ G PG+ PG G PG+ LPG P G Sbjct: 212 QPGLPGAPGQGGAPGPPGL-PGPA--GLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGA 268 Query: 175 VKPKAP-GVGGAFAGIPGVGPFGGPQ-PGVPLGYPIKA--PKL--PGGYGLPYTTGKLPY 228 V PK P GV G G+PG GPQ P G P P L P GYG+P G P Sbjct: 269 VGPKGPPGVDGV--GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPG--PK 324 Query: 229 G-YGPGGVAGAAGKAGYPTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVP 283 G GP GV G G G P G GPQ + G G PG G P Sbjct: 325 GDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGP-PGPKGEAGP 383 Query: 284 GVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPG 343 G P +PGI G G A + GA P GP PG G PG G Sbjct: 384 GGPPGVPGIRG--DQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPG----G 437 Query: 344 VGVPGA-------GIPVVPG----AGIPGAAVP-GVVSPEAAAKAAAKAAKYGARPGVGV 391 GV GA G+P PG +GIPG P G + P+ G + G+ Sbjct: 438 PGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP---------GLKGEPGL 488 Query: 392 GGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEA 441 G P G G G PG G G PGV G PG+ G PG G PG +P A Sbjct: 489 PGPP--GEGRAGEPGTA-GPTGPPGVPGSPGITGPPGPPGPPGPPGAPGA 535 Score = 112 bits (281), Expect = 9e-25 Identities = 170/576 (29%), Positives = 209/576 (36%), Gaps = 100/576 (17%) Query: 174 GVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK-----LPY 228 G P+A GGA GG P+ Y P G G P+ GK +P Sbjct: 21 GCGPRASSGGGA----------GGAAGYAPVKYI--QPMQKGPVGPPFREGKGQYLEMPL 68 Query: 229 GYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGA 288 P + G G G P GP+ G G PG PG Sbjct: 69 PLLPMDLKGEPGPPGKP-----GPR------------------------GPPGPPGFPGK 99 Query: 289 IPGIG--GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGA-GVPG 343 PG+G G+ G PA + KA G +PG GP PG+ G PG G G Sbjct: 100 -PGMGKPGLHGQPGPAGPPGFSRMGKAGPPG-----LPGKVGPPGQPGLRGEPGIRGDQG 153 Query: 344 VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV-GVGGIPTYGVGAG 402 + P G P +PG G +PG + A+ + PG G G P G Sbjct: 154 LRGP-PGPPGLPGPS--GITIPG----KPGAQGVPGPPGFQGEPGPQGEPGPP----GDR 202 Query: 403 GFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG-VGI-SPEAQAAAAAKAAKYGVGTPAAA 460 G G GVG PG+ G PG GG PG G+PG G+ P A K G P Sbjct: 203 GLKGDN-GVGQ-PGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVP 260 Query: 461 AAKAAAKAAQFGLVPGV-GV-APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 518 + A PGV GV PG PG G PG PG+ G G+ PG Sbjct: 261 GPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGM-PG 319 Query: 519 I-------GPGGVAAAAKSAAKVAAKAQ--LRAAAGLGAGIPGLGVGVGVPGLGVGAGVP 569 + GP GV + + + GLG G PGL G+PG G Sbjct: 320 LPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLG-GPPGLPGSAGLPGRRGPPGPK 378 Query: 570 GLGVGAGVPGFGAV-----PGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGV---VGA 621 G G PG + P LA +PG G G G G PG G Sbjct: 379 GEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGP 438 Query: 622 GPAAAAAAAKAAAKAAQFGLVGAAGLGGL-----GVGGLGVPGVGGLGGIP-PAAAAKAA 675 G A A Q GL G +G+ GL +G G+PG+ G G+P P +A Sbjct: 439 GVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAG 498 Query: 676 KYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 711 + G AG G G G + G PG P PG Sbjct: 499 EPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPG 534 Score = 93.2 bits (230), Expect = 8e-19 Identities = 143/466 (30%), Positives = 171/466 (36%), Gaps = 107/466 (22%) Query: 23 PSRPG--GVPGAIPG--GVPGGVFYPG--AGLGALGGGALGPGGKPLKPVPGGLAGA-GL 75 P +PG GVPG PG G PG PG G G +G G P P GG G GL Sbjct: 172 PGKPGAQGVPGP-PGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGL 230 Query: 76 G--AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAG----AGLGGVPGVGGLGVSAGAVV 129 AGLG PGA PG ++ G G G PGV G+GV A + Sbjct: 231 PGPAGLGKPGLDGLPGA--PGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGL 288 Query: 130 P----------QPGAGVKPGKV--PGVGLPGVYPG-----------GVLPGARFPGVGVL 166 P +PG PG + G G+PG+ PG G+L PG Sbjct: 289 PGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGL-PGPKGDRGPAGVPGLLGDRGEPGEDGE 347 Query: 167 PGV--PTGAGVKPKAPGVGGAFAGIPG----VGPFGGPQPGVPLGYP-IKAPKLPGGY-G 218 PG P G G P PG AG+PG GP G PG P G P I+ + P G G Sbjct: 348 PGEQGPQGLGGPPGLPGS----AGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAG 403 Query: 219 LPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGA-------- 268 P G+ LP +GP G G G+ G+ TG GP A A K Sbjct: 404 KPGVPGERGLPGAHGPPGPTGPKGEPGF-TGRPGGPGVAGALGQKGDLGLPGQPGLRGPS 462 Query: 269 ------GAAGVL-----------------PGVGGAGVPGVPG-----AIPGIGGIAGVGT 300 G AG + PG G AG PG G +PG GI G Sbjct: 463 GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPG 522 Query: 301 PAAAAAAAAAAKAAKYGAAAGL-VPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGI 359 P A A AGL +P G GV GA + G P G+ + Sbjct: 523 PPGPPGPPGAPGAFDETGIAGLHLPNG--------GVEGAVLGKGGKPQFGLGELSAHAT 574 Query: 360 PGAAVPGVVSPEAAAKAAAKAAK------YGARPGVGVGGIPTYGV 399 P A + SP A+ K + G P G+ P GV Sbjct: 575 P-AFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGV 619 Score = 52.8 bits (125), Expect = 1e-06 Identities = 51/159 (32%), Positives = 59/159 (37%), Gaps = 11/159 (6%) Query: 567 GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAA 626 G PG G PGF PG + G A P +G G G+PG V GP Sbjct: 83 GKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKV---GPPGQ 139 Query: 627 AAAAKAAAKAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGIP--PAAAAKAAKYGAAGLG 683 GL G G GL G G+ +PG G G+P P + G G Sbjct: 140 PGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPP 199 Query: 684 GVLG-----GAGQFPLGGVAARPGFGLSPIFPGGACLGK 717 G G G GQ L G + G P PG A LGK Sbjct: 200 GDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGK 238 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 142 bits (357), Expect = 1e-33 Identities = 215/738 (29%), Positives = 253/738 (34%), Gaps = 134/738 (18%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTF 87 G PG P G PG PG G +GP G P +P P GL G G P VT Sbjct: 646 GDPG--PSGPPGP---PGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVT- 699 Query: 88 PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGAGVKPGKVPGVG 145 G+ G PG G V PQ PG + G G Sbjct: 700 -----------------------GMDGQPG------PKGNVGPQGEPGPPGQQGNPGAQG 730 Query: 146 LPGVYPGGVL--PGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGV 202 LPG P G + PG + P G LPG+P GA P PG G G GP P P Sbjct: 731 LPG--PQGAIGPPGEKGPLGKPGLPGMP-GADGPPGHPGKEGPPGEKGGQGP---PGPQG 784 Query: 203 PLGYPIKAPK----LPGGYGLPYTTGK-----LPYGYGPGGVAGAAGKAGYPTGTGV-GP 252 P+GYP P+ G GL T G+ P G G+ G G+ G P G GP Sbjct: 785 PIGYP--GPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGP 842 Query: 253 QAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAK 312 + G G +G G+PG PG G I G P A Sbjct: 843 EGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGT 902 Query: 313 AAKYGAAAGLVPGGPGF--GP-GVVGVPG----------AGVPG----------VGVPGA 349 K G P GP GP G+ G PG AG PG G PG Sbjct: 903 PGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGP 962 Query: 350 -GIPVVPGA-GIPG----------------AAVPGVVSPEAAAKAAAKAAKYGARPGVGV 391 G P PG G+PG PGVV P+ + G R G Sbjct: 963 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPT---GETGPMGERGHPGP 1019 Query: 392 GGIPTYGVGAGGFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKA 449 G P G G PG G G PG AG+PG G PG+ G PG P A K Sbjct: 1020 PGPP----GEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKG 1075 Query: 450 AKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGVGLAPG----VGVAP 505 + G P A + A G+ PG PG G APG G A Sbjct: 1076 NEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKG---APGEKGPQGPAG 1132 Query: 506 GVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-------------AGIPG 552 G+ VG+ GP G ++ Q + G G PG Sbjct: 1133 RDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPG 1192 Query: 553 LGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGV 612 G PG G+ G G GF PG + PG G G +G + Sbjct: 1193 PSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGL----PGPPGEKGETGDVGQM 1248 Query: 613 GIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAA 672 G PG GP+ A A G GA G G G G PG+ G GG PP Sbjct: 1249 GPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKG-EPGEAGEPGLPGEGG-PPGPKG 1306 Query: 673 KAAKYGAAGLGGVLGGAG 690 + + G +G G G G Sbjct: 1307 ERGEKGESGPSGAAGPPG 1324 Score = 129 bits (323), Expect = 1e-29 Identities = 223/796 (28%), Positives = 262/796 (32%), Gaps = 155/796 (19%) Query: 18 LSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG-KPLKPVPGGLAGAGLG 76 L++ P+ P G+ G PG V PG+G G +GP G + ++ PG G Sbjct: 555 LALRGPAGPMGLTGR-----PGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRR 609 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGA 134 G+ A PG P K + GL G+PG G G P PG Sbjct: 610 GRAGSDGARGMPGQTGP----------KGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD 659 Query: 135 GVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG--- 191 + G VG G LPG PG L G P G P PGV G G PG Sbjct: 660 DGERGDDGEVGPRG------LPGE--PGPRGLLG-PKGPPGPPGPPGVTG-MDGQPGPKG 709 Query: 192 -VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV 250 VGP G P P G P G GLP G + GP G G GK G P G Sbjct: 710 NVGPQGEPGPPGQQGNP-------GAQGLPGPQGAI----GPPGEKGPLGKPGLPGMPGA 758 Query: 251 -GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG------------ 297 GP K G G G +G G GV GA GI G+ G Sbjct: 759 DGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGA-DGIRGLKGTKGEKGEDGFPG 817 Query: 298 ----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPGV-GVPG 348 +G + G GGP PG +G PG GVPG+ G PG Sbjct: 818 FKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPG 877 Query: 349 A-------GIPVVPGA-------GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVG 390 G P PGA G PG P G P K G + G Sbjct: 878 RQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSG 937 Query: 391 VGGI--------PTYGVGAGGFPG--------FGVGVGGIPGVAGVPGVGGVPGVGGVPG 434 G P G GFPG G+ G PG G G G G G PG Sbjct: 938 GDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPG 997 Query: 435 VGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPG 494 V + P+ + G P + +PG+ G PG PG Sbjct: 998 V-VGPQGPTGETGPMGERGHPGPPGPPGEQG--------LPGLAGKEGTKGDPGPAGLPG 1048 Query: 495 VGLAPGVGVAPGVGVAPG----VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-- 548 PG+ PG PG +G+ GP G A S + R AG Sbjct: 1049 KDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGE-------RGPAGAAGPI 1101 Query: 549 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA-----------KYGA 597 GIPG G PG G PG G G + G + A K Sbjct: 1102 GIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEI 1161 Query: 598 AVPGVLGGLGALGGVGIPG-----GVVGA-GPAAAAAAAKAAAKAAQFGLVGAAGLGGLG 651 PG G G G G PG G +G GP+ A + FG G G G Sbjct: 1162 GEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFP 1221 Query: 652 -----VGGLGVPGVGGLGGI-----------PPAAAAKAAKYGAAGLGGVLGGAGQFPLG 695 VG G+PG G G PP + GA G G GG G Sbjct: 1222 GPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAV 1281 Query: 696 GVAARPGFGLSPIFPG 711 G PG P PG Sbjct: 1282 GEKGEPGEAGEPGLPG 1297 Score = 115 bits (289), Expect = 1e-25 Identities = 199/706 (28%), Positives = 230/706 (32%), Gaps = 93/706 (13%) Query: 26 PGGVPGAI-PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPA 84 P G PG P G G +PG P G P P GL G G F Sbjct: 941 PAGPPGERGPNGPQGPTGFPG------------PKGPPGPPGKDGLPGHPGQRGETGFQG 988 Query: 85 VTFPGALVPGGVADAAAAYKAAKAGA----GLGGVPGVGGLGVSAG--AVVPQPGAGVKP 138 T P PG V + G G G PG GL AG PG P Sbjct: 989 KTGPPG-PPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLP 1047 Query: 139 GKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFGG 197 GK GL G FPG LPG G+K G PG GP G Sbjct: 1048 GKDGPPGLRG-----------FPGDRGLPGPVGALGLKGNE--------GPPGPPGPAGS 1088 Query: 198 PQPGVPLGY--PIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQ 253 P P G PI P PG G P G+ P GP G AG G G P G GP Sbjct: 1089 PGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQG-PVGLP-GPA 1146 Query: 254 AAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKA 313 + K G G G G G PG G I G A + Sbjct: 1147 GPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ 1206 Query: 314 AKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV-----GVPGAGIPVVPGAGIPGAAVPGV 367 +G P G PG VG+ G G PG V G P PG P A PG Sbjct: 1207 GLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGA-PGA 1265 Query: 368 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVP 427 P+ G + G G P G GG PG G G G +G G G P Sbjct: 1266 DGPQGPPGGIGNPGAVGEKGEPGEAGEPGLP-GEGGPPG-PKGERGEKGESGPSGAAGPP 1323 Query: 428 GVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAP 487 G G PG + G P A PG +PG P Sbjct: 1324 GPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEP 1383 Query: 488 GVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAA--AAKSAAKVAAKAQLRAAA 544 G PG PG G G G+ GP G + A LR Sbjct: 1384 GPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIP 1443 Query: 545 G-LGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGV 602 G +G G+PG G PG G+PGL +G G PG + + G Sbjct: 1444 GPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLI----------GLIGP 1493 Query: 603 LGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGG 662 G G G G+PG +GP + G+ G + G +G PG G Sbjct: 1494 PGEQGEKGDRGLPGPQGSSGP------------KGEQGITGPS-------GPIGPPGPPG 1534 Query: 663 LGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPI 708 L G P AK G++G G G AG G PG + P+ Sbjct: 1535 LPGPPGPKGAK----GSSGPTGPKGEAGHPGPPGPPGPPGEVIQPL 1576 Score = 98.6 bits (244), Expect = 2e-20 Identities = 181/659 (27%), Positives = 217/659 (32%), Gaps = 102/659 (15%) Query: 116 PGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY-PGGVLPGARFPGVGVLPGVPTGAG 174 P G G+ A G G G+ G P + PG ++ G P P G Sbjct: 427 PSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEG---------PPGPEGPA 477 Query: 175 VKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK---LPYGYG 231 P PG G G G P P G P LPG GLP G LP+ +G Sbjct: 478 GLPGPPGTMGP------TGQVGDPGERGPPG----RPGLPGADGLPGPPGTMLMLPFRFG 527 Query: 232 PGGVAGAAG---KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGA 288 GG AG+ G A + QA A A G G + G G+ G PG Sbjct: 528 GGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD 587 Query: 289 IPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV---- 344 + G G P A +A GA GP G G+ AG+PG Sbjct: 588 VGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGL--AGLPGEKGHR 645 Query: 345 GVPG-AGIPVVPG-------------AGIPGAAVP-GVVSPEAAAKAAAKAAKYG--ARP 387 G PG +G P PG G+PG P G++ P+ G +P Sbjct: 646 GDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQP 705 Query: 388 GVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPG----VG--------GVPGVGGVPGV 435 G P VG G PG G G PG G+PG +G G PG+ G+PG Sbjct: 706 G------PKGNVGPQGEPG-PPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGA 758 Query: 436 GISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGVGVAPGV 495 P K G G P PG GV A G+ G Sbjct: 759 DGPPGHPGKEGPPGEKGGQGPPGPQGPIG---------YPG---PRGVKGADGIRGLKGT 806 Query: 496 GLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 554 G PG G+ G IGP G LG PG Sbjct: 807 KGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGP--PGEK 864 Query: 555 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 614 +GVPGL G PG G GF PG A K G PG G G G G Sbjct: 865 GKLGVPGL---PGYPGRQGPKGSIGFPGFPG----ANGEKGGRGTPGKPGPRGQRGPTGP 917 Query: 615 -----PGGVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPP 668 P G+ G GP + A + G G G G G G PG G G+P Sbjct: 918 RGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGF-PGPKGPPGPPGKDGLPG 976 Query: 669 AAAAKA-----AKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRK 722 + K G G GV+G G G G P PG L G++ Sbjct: 977 HPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKE 1035 Score = 82.8 bits (203), Expect = 1e-15 Identities = 135/451 (29%), Positives = 156/451 (34%), Gaps = 54/451 (11%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-------GALGPGGKPLKPVPGGLAGA-- 73 P+ P G PG G G + PG G+ G G GP G +P P G G Sbjct: 1145 PAGPVGPPGE--DGDKGEIGEPGQK-GSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG 1201 Query: 74 -----GLGAGLGAFPAVTFPGALVPGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSAG 126 GL G FPG P G+ K G G PG G +G Sbjct: 1202 PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSG 1261 Query: 127 AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGV 182 A PGA G G+G PG PG PG G PG P G + G Sbjct: 1262 A----PGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPG-PKGERGEKGESGP 1316 Query: 183 GGAFAGIPGVGPFGGPQPGVPLGYP--IKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGA 238 GA AG PG P G P P G P + P PG G P G+ P G G G Sbjct: 1317 SGA-AGPPG--PKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQ 1373 Query: 239 AGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV 298 G G PTG GP G G G AG+ G PG IG Sbjct: 1374 TGSPG-PTGEP-GPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAP 1431 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA--GIPVVP 355 G P + G P GP PG +G PG G+ G P G P + Sbjct: 1432 GKPGPDGLRGIPGPVGEQGLPGSPGPDGP---PGPMGPPGLPGLKGDSGPKGEKGHPGLI 1488 Query: 356 GA-GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG--FG 408 G G PG G+ P+ ++ + G +G G P G G PG Sbjct: 1489 GLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPP----GLPGPPGPKGA 1544 Query: 409 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 439 G G G G G G PG G PG I P Sbjct: 1545 KGSSGPTGPKGEAGHPGPPGPPGPPGEVIQP 1575 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.143 0.441 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,888,627 Number of Sequences: 37866 Number of extensions: 3080250 Number of successful extensions: 62488 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 501 Number of HSP's successfully gapped in prelim test: 941 Number of HSP's that attempted gapping in prelim test: 14573 Number of HSP's gapped (non-prelim): 14147 length of query: 724 length of database: 18,247,518 effective HSP length: 110 effective length of query: 614 effective length of database: 14,082,258 effective search space: 8646506412 effective search space used: 8646506412 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.