Guide to the Human Genome
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Search of human proteins with 12597641

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12597641 leucine rich repeat containing 19 [Homo sapiens]
         (370 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12597641 leucine rich repeat containing 19 [Homo sapiens]          751   0.0  
gi|59823631 G protein-coupled receptor 125 [Homo sapiens]              87   2e-17
gi|194272183 G protein-coupled receptor 124 [Homo sapiens]             82   1e-15
gi|40217825 slit and trk like 6 [Homo sapiens]                         81   2e-15
gi|116268101 leucine rich repeat containing 62 [Homo sapiens]          80   2e-15
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s...    79   5e-15
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa...    79   5e-15
gi|109150416 peroxidasin [Homo sapiens]                                79   7e-15
gi|188528675 slit homolog 1 [Homo sapiens]                             74   2e-13
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]       74   2e-13
gi|40217820 slit and trk like 3 protein [Homo sapiens]                 72   6e-13
gi|40217817 slit and trk like 1 protein [Homo sapiens]                 72   8e-13
gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]         71   1e-12
gi|10190722 leucine-rich repeats and transmembrane domains 1 [Ho...    71   2e-12
gi|27436867 slit and trk like 4 protein [Homo sapiens]                 70   2e-12
gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens]        69   5e-12
gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens]        69   5e-12
gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens]        69   5e-12
gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens]        69   5e-12
gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens]        69   5e-12
gi|221136965 SLIT and NTRK-like family, member 2 [Homo sapiens]        69   5e-12
gi|221136961 SLIT and NTRK-like family, member 2 [Homo sapiens]        69   5e-12
gi|221136957 SLIT and NTRK-like family, member 2 [Homo sapiens]        69   5e-12
gi|33504581 SLIT and NTRK-like family, member 2 [Homo sapiens]         69   5e-12
gi|198041768 synleurin [Homo sapiens]                                  67   2e-11
gi|4759146 slit homolog 2 [Homo sapiens]                               67   3e-11
gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens]    66   4e-11
gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens]     66   4e-11
gi|150417978 platelet glycoprotein Ib alpha polypeptide precurso...    65   7e-11
gi|11321571 slit homolog 3 [Homo sapiens]                              65   7e-11

>gi|12597641 leucine rich repeat containing 19 [Homo sapiens]
          Length = 370

 Score =  751 bits (1939), Expect = 0.0
 Identities = 370/370 (100%), Positives = 370/370 (100%)

Query: 1   MKVTGITILFWPLSMILLSDKIQSSKREVQCNFTEKNYTLIPADIKKDVTILDLSYNQIT 60
           MKVTGITILFWPLSMILLSDKIQSSKREVQCNFTEKNYTLIPADIKKDVTILDLSYNQIT
Sbjct: 1   MKVTGITILFWPLSMILLSDKIQSSKREVQCNFTEKNYTLIPADIKKDVTILDLSYNQIT 60

Query: 61  LNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGL 120
           LNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGL
Sbjct: 61  LNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGL 120

Query: 121 NKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDVPPLFHLELITLYGNLWNC 180
           NKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDVPPLFHLELITLYGNLWNC
Sbjct: 121 NKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDVPPLFHLELITLYGNLWNC 180

Query: 181 SCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTEDLYI 240
           SCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTEDLYI
Sbjct: 181 SCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTEDLYI 240

Query: 241 HFQPISNSIFNSSSNNLTRNSEHEPLGKSWAFLVGVVVTVLTTSLLIFIAIKCPIWYNIL 300
           HFQPISNSIFNSSSNNLTRNSEHEPLGKSWAFLVGVVVTVLTTSLLIFIAIKCPIWYNIL
Sbjct: 241 HFQPISNSIFNSSSNNLTRNSEHEPLGKSWAFLVGVVVTVLTTSLLIFIAIKCPIWYNIL 300

Query: 301 LSYNHHRLEEHEAETYEDGFTGNPSSLSQIPETNSEETTVIFEQLHSFVVDDDGFIEDKY 360
           LSYNHHRLEEHEAETYEDGFTGNPSSLSQIPETNSEETTVIFEQLHSFVVDDDGFIEDKY
Sbjct: 301 LSYNHHRLEEHEAETYEDGFTGNPSSLSQIPETNSEETTVIFEQLHSFVVDDDGFIEDKY 360

Query: 361 IDIHELCEEN 370
           IDIHELCEEN
Sbjct: 361 IDIHELCEEN 370


>gi|59823631 G protein-coupled receptor 125 [Homo sapiens]
          Length = 1321

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 59/149 (39%), Positives = 78/149 (52%), Gaps = 12/149 (8%)

Query: 78  LYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLN 137
           L L  NK++ L N  F  LS LE L++  N I  I  GAF GL+ LK+L L  N+I  LN
Sbjct: 86  LILSNNKISELKNGSFSGLSLLERLDLRNNLISSIDPGAFWGLSSLKRLDLTNNRIGCLN 145

Query: 138 ADVFVPLRSLKLLNLQGNLISYLD------VPPLFHLELITLYGNLWNCSCSLFNLQNWL 191
           AD+F  L +L  LNL GNL S L       +  L  LE  T Y     C C++  +  W+
Sbjct: 146 ADIFRGLTNLVRLNLSGNLFSSLSQGTFDYLASLRSLEFQTEY---LLCDCNILWMHRWV 202

Query: 192 NTSNVTLENENITMCSYPNSLQSYNIKTV 220
              N+T+ +   T C YP SLQ+  +  V
Sbjct: 203 KEKNITVRD---TRCVYPKSLQAQPVTGV 228


>gi|194272183 G protein-coupled receptor 124 [Homo sapiens]
          Length = 1338

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 55/153 (35%), Positives = 80/153 (52%), Gaps = 7/153 (4%)

Query: 78  LYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLN 137
           L L  NK+T L N  F  LS LE L++  N I  +Q GAFLGL +LK+L L  N+I  L 
Sbjct: 89  LLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLT 148

Query: 138 ADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGNLWNCSCSLFNLQNWLNT 193
           ++ F  L  L  LN+ GN+ S L  P +F     L+++ L      C C L  L  W   
Sbjct: 149 SETFQGLPRLLRLNISGNIFSSLQ-PGVFDELPALKVVDLGTEFLTCDCHLRWLLPW--A 205

Query: 194 SNVTLENENITMCSYPNSLQSYNIKTVPHKAEC 226
            N +L+    T+C+YP++L +  + ++     C
Sbjct: 206 QNRSLQLSEHTLCAYPSALHAQALGSLQEAQLC 238


>gi|40217825 slit and trk like 6 [Homo sapiens]
          Length = 841

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 60/203 (29%), Positives = 92/203 (45%), Gaps = 34/203 (16%)

Query: 69  LQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYL 128
           L  YF L  L+L  N++ +L    F NL+ L+ L +  N +  + +G FLGL+ L+ LYL
Sbjct: 383 LVEYFTLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYL 442

Query: 129 CQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDVPP------------------------ 164
             N I+++    F P+  LK+L L  NL+  L  PP                        
Sbjct: 443 EYNAIKEILPGTFNPMPKLKVLYLNNNLLQVL--PPHIFSGVPLTKVNLKTNQFTHLPVS 500

Query: 165 --LFHLELIT---LYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNIKT 219
             L  L+L+T   L  N W+CSC L  LQ W+   +     ++I +C+ P  L    +K 
Sbjct: 501 NILDDLDLLTQIDLEDNPWDCSCDLVGLQQWIQKLSKNTVTDDI-LCTSPGHLDKKELKA 559

Query: 220 VPHKAECHS--KFPSSVTEDLYI 240
           +  +  C      PS  T+  Y+
Sbjct: 560 LNSEILCPGLVNNPSMPTQTSYL 582



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 47/123 (38%), Positives = 62/123 (50%), Gaps = 7/123 (5%)

Query: 74  LLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKI 133
           LL +L++  N + IL  + F  L +LE L    N I VI+  AF  LN+LK L L  N I
Sbjct: 113 LLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAI 172

Query: 134 EQLNADVF--VPLRSLKLLNLQGNLISYLDVPPLFHLELIT---LYGNLWNCSCSLFNLQ 188
           E L  ++F  VPL  L L   Q   + Y+    L H+  I    L  N W C+C L  L+
Sbjct: 173 ESLPPNIFRFVPLTHLDLRGNQLQTLPYVGF--LEHIGRILDLQLEDNKWACNCDLLQLK 230

Query: 189 NWL 191
            WL
Sbjct: 231 TWL 233


>gi|116268101 leucine rich repeat containing 62 [Homo sapiens]
          Length = 820

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 54/188 (28%), Positives = 86/188 (45%), Gaps = 5/188 (2%)

Query: 31  CNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHN 90
           C+  +  Y  IP  I    T+ DL  N+  L       L  +  LT+L L +N+++ + +
Sbjct: 39  CSQNQPPYETIPQHINS--TVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIED 96

Query: 91  NGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLL 150
             F   SSL++L +  N +  + +G   G+++L+ L++  N IE +    F    SL  +
Sbjct: 97  GAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISI 156

Query: 151 NLQGNLISYLD---VPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCS 207
           +L  N +S LD      L  L +  L GN +NC C LF    WL   N   +N +   C 
Sbjct: 157 DLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCE 216

Query: 208 YPNSLQSY 215
            P     Y
Sbjct: 217 SPREFAGY 224


>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
           sapiens]
          Length = 587

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 54/193 (27%), Positives = 92/193 (47%), Gaps = 32/193 (16%)

Query: 57  NQITLNGTDTRVLQTYFL-----LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYV 111
           N++TL G   + L          L EL+L +N ++ L +N F NL  L++L + RN I  
Sbjct: 278 NRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISF 337

Query: 112 IQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYL------DVPPL 165
           I  GAF GL +L++L L  N ++ L+ +VF  L +L+ ++LQ N +  L      +V  L
Sbjct: 338 ISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGL 397

Query: 166 FHLEL---------------------ITLYGNLWNCSCSLFNLQNWLNTSNVTLENENIT 204
             ++L                     + LY N W C   +  L+NWL  +   L  + + 
Sbjct: 398 MAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVP 457

Query: 205 MCSYPNSLQSYNI 217
           +C  P +++  ++
Sbjct: 458 VCFSPANVRGQSL 470



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 43/131 (32%), Positives = 65/131 (49%), Gaps = 5/131 (3%)

Query: 49  VTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNS 108
           +T L+L  N +T      RV Q    L  L L EN++T +    F  L +L+ L + +N 
Sbjct: 181 LTKLNLGKNSLT--HISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQ 238

Query: 109 IYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDV---PPL 165
           I ++  G F   + L++LYL  N I QL   +F+ L  L  L L GN +  L +    P+
Sbjct: 239 IGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPM 298

Query: 166 FHLELITLYGN 176
            +L  + LY N
Sbjct: 299 PNLRELWLYDN 309



 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 36/116 (31%), Positives = 58/116 (50%), Gaps = 4/116 (3%)

Query: 61  LNGTDTRVLQTYFL----LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGA 116
           LN   T + ++ FL    L  L + +N+++ +    F NL SL  L++  N + V+  G 
Sbjct: 67  LNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGL 126

Query: 117 FLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDVPPLFHLELIT 172
           F GL+ L+ L L  N++ Q+    F    +LK L L GN + Y+      HL  +T
Sbjct: 127 FQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLT 182



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 8/134 (5%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  LYL  N ++ L  + F  L  L  L +  NS+  +  G F  +  L++L+L  N I 
Sbjct: 253 LQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHIS 312

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGN-LWNCSCSLFNLQN 189
            L  +VF  LR L++L L  N IS++  P  F+    L  ++L+ N L +   ++F +  
Sbjct: 313 SLPDNVFSNLRQLQVLILSRNQISFIS-PGAFNGLTELRELSLHTNALQDLDGNVFRM-- 369

Query: 190 WLNTSNVTLENENI 203
             N  N++L+N  +
Sbjct: 370 LANLQNISLQNNRL 383



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 7/104 (6%)

Query: 78  LYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLN 137
           L ++   +T L+ + F N+S+L  L I +N +  I  GAF  L  L+ L L  NK++ L 
Sbjct: 64  LQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLP 123

Query: 138 ADVFVPLRSLKLLNLQGNLISYLDVPPLF-----HLELITLYGN 176
             +F  L SL+ L L  N +  L + P       +L+ + L+GN
Sbjct: 124 IGLFQGLDSLESLLLSSNQL--LQIQPAHFSQCSNLKELQLHGN 165



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 6/164 (3%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L L  NK+ +L    F  L SLE L +  N +  IQ   F   + LK+L L  N +E
Sbjct: 109 LRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLE 168

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLF----HLELITLYGNLWNCSCSLFNLQNW 190
            +    F  L  L  LNL  N ++++  P +F    +L+++ LY N       +      
Sbjct: 169 YIPDGAFDHLVGLTKLNLGKNSLTHIS-PRVFQHLGNLQVLRLYENRLT-DIPMGTFDGL 226

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSV 234
           +N   + L+   I + S      ++N++ +       S+ P S+
Sbjct: 227 VNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSI 270



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 4/136 (2%)

Query: 18  LSDKIQSSKREVQCNFTEKNYT--LIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLL 75
           L D + S+ R++Q     +N    + P        + +LS +   L   D  V +    L
Sbjct: 314 LPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANL 373

Query: 76  TELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQ 135
             + L  N++  L  N F N++ L  + +  N +  +  G F  L KL +L L  N   +
Sbjct: 374 QNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNP-WR 432

Query: 136 LNADVFVPLRSLKLLN 151
            ++D+ +PLR+  LLN
Sbjct: 433 CDSDI-LPLRNWLLLN 447


>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
           sapiens]
          Length = 581

 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 54/193 (27%), Positives = 92/193 (47%), Gaps = 32/193 (16%)

Query: 57  NQITLNGTDTRVLQTYFL-----LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYV 111
           N++TL G   + L          L EL+L +N ++ L +N F NL  L++L + RN I  
Sbjct: 272 NRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISF 331

Query: 112 IQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYL------DVPPL 165
           I  GAF GL +L++L L  N ++ L+ +VF  L +L+ ++LQ N +  L      +V  L
Sbjct: 332 ISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGL 391

Query: 166 FHLEL---------------------ITLYGNLWNCSCSLFNLQNWLNTSNVTLENENIT 204
             ++L                     + LY N W C   +  L+NWL  +   L  + + 
Sbjct: 392 MAIQLQNNQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWLLLNQPRLGTDTVP 451

Query: 205 MCSYPNSLQSYNI 217
           +C  P +++  ++
Sbjct: 452 VCFSPANVRGQSL 464



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 43/131 (32%), Positives = 65/131 (49%), Gaps = 5/131 (3%)

Query: 49  VTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNS 108
           +T L+L  N +T      RV Q    L  L L EN++T +    F  L +L+ L + +N 
Sbjct: 175 LTKLNLGKNSLT--HISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQ 232

Query: 109 IYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDV---PPL 165
           I ++  G F   + L++LYL  N I QL   +F+ L  L  L L GN +  L +    P+
Sbjct: 233 IGLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPM 292

Query: 166 FHLELITLYGN 176
            +L  + LY N
Sbjct: 293 PNLRELWLYDN 303



 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 36/116 (31%), Positives = 58/116 (50%), Gaps = 4/116 (3%)

Query: 61  LNGTDTRVLQTYFL----LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGA 116
           LN   T + ++ FL    L  L + +N+++ +    F NL SL  L++  N + V+  G 
Sbjct: 61  LNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGL 120

Query: 117 FLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDVPPLFHLELIT 172
           F GL+ L+ L L  N++ Q+    F    +LK L L GN + Y+      HL  +T
Sbjct: 121 FQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLT 176



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 8/134 (5%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  LYL  N ++ L  + F  L  L  L +  NS+  +  G F  +  L++L+L  N I 
Sbjct: 247 LQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHIS 306

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGN-LWNCSCSLFNLQN 189
            L  +VF  LR L++L L  N IS++  P  F+    L  ++L+ N L +   ++F +  
Sbjct: 307 SLPDNVFSNLRQLQVLILSRNQISFIS-PGAFNGLTELRELSLHTNALQDLDGNVFRM-- 363

Query: 190 WLNTSNVTLENENI 203
             N  N++L+N  +
Sbjct: 364 LANLQNISLQNNRL 377



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 7/104 (6%)

Query: 78  LYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLN 137
           L ++   +T L+ + F N+S+L  L I +N +  I  GAF  L  L+ L L  NK++ L 
Sbjct: 58  LQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLP 117

Query: 138 ADVFVPLRSLKLLNLQGNLISYLDVPPLF-----HLELITLYGN 176
             +F  L SL+ L L  N +  L + P       +L+ + L+GN
Sbjct: 118 IGLFQGLDSLESLLLSSNQL--LQIQPAHFSQCSNLKELQLHGN 159



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 6/164 (3%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L L  NK+ +L    F  L SLE L +  N +  IQ   F   + LK+L L  N +E
Sbjct: 103 LRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLE 162

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLF----HLELITLYGNLWNCSCSLFNLQNW 190
            +    F  L  L  LNL  N ++++  P +F    +L+++ LY N       +      
Sbjct: 163 YIPDGAFDHLVGLTKLNLGKNSLTHIS-PRVFQHLGNLQVLRLYENRLT-DIPMGTFDGL 220

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSV 234
           +N   + L+   I + S      ++N++ +       S+ P S+
Sbjct: 221 VNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPSI 264



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 4/136 (2%)

Query: 18  LSDKIQSSKREVQCNFTEKNYT--LIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLL 75
           L D + S+ R++Q     +N    + P        + +LS +   L   D  V +    L
Sbjct: 308 LPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANL 367

Query: 76  TELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQ 135
             + L  N++  L  N F N++ L  + +  N +  +  G F  L KL +L L  N   +
Sbjct: 368 QNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYDNP-WR 426

Query: 136 LNADVFVPLRSLKLLN 151
            ++D+ +PLR+  LLN
Sbjct: 427 CDSDI-LPLRNWLLLN 441


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 65/203 (32%), Positives = 102/203 (50%), Gaps = 11/203 (5%)

Query: 41  IPADIKKDVTILDLSYNQIT-LNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSL 99
           +PA +    +ILDL +N+I  +     R L+    L  L L  N++  + +  F +L +L
Sbjct: 57  VPA-VAPQTSILDLRFNRIREIQPGAFRRLRN---LNTLLLNNNQIKRIPSGAFEDLENL 112

Query: 100 EILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISY 159
           + L + +N I  I + AF GL  L+QLYL  N+IE L+ D F  L  L+ L L  N I++
Sbjct: 113 KYLYLYKNEIQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITH 172

Query: 160 LDVPPLF-HLE---LITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSY 215
           L VP  F HLE    + L  N  +C C +  L + L T   +   +   +C YP  +Q  
Sbjct: 173 L-VPGTFNHLESMKRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGR 231

Query: 216 NIKTV-PHKAECHSKFPSSVTED 237
           ++ T+ P +  C     +S  +D
Sbjct: 232 SVATITPEELNCERPRITSEPQD 254


>gi|188528675 slit homolog 1 [Homo sapiens]
          Length = 1534

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 57/210 (27%), Positives = 100/210 (47%), Gaps = 9/210 (4%)

Query: 14  SMILLSDKIQSSKREVQCNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYF 73
           S ++   K +     V+C+  +   T IP  I +    L L+ N+I++    T + +   
Sbjct: 509 SDVVCPHKCRCEANVVECSSLK--LTKIPERIPQSTAELRLNNNEISILEA-TGMFKKLT 565

Query: 74  LLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKI 133
            L ++ L  NKV+ + +  F   +S+  L++  N +  I+ G F GL+ L+ L L  N+I
Sbjct: 566 HLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRI 625

Query: 134 EQLNADVFVPLRSLKLLNLQGNLISYLD---VPPLFHLELITLYGNLWNCSCSLFNLQNW 190
             ++ D F  LR+++LL+L  N I+ +       L  L  + L  N +NC+C L  L  W
Sbjct: 626 SCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGW 685

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTV 220
           L    +   N     C  P+ L+   ++ V
Sbjct: 686 LRKRKIVTGNPR---CQNPDFLRQIPLQDV 712



 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 60/199 (30%), Positives = 86/199 (43%), Gaps = 30/199 (15%)

Query: 29  VQCNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTIL 88
           V+C+   K+   +P  I K+VT L L  NQ TL       L T+  L  + L  NK++ L
Sbjct: 745 VRCS--NKHLRALPKGIPKNVTELYLDGNQFTLVPGQ---LSTFKYLQLVDLSNNKISSL 799

Query: 89  HNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLK 148
            N+ F N+S L  L +  N++  I   AF GL  L+ L L  N I  L   +F  + SL 
Sbjct: 800 SNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLS 859

Query: 149 LLNLQGNLISYLDVPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSY 208
            L +  N        PL+             C C L  L +W+ T     +   I  C+ 
Sbjct: 860 HLAIGAN--------PLY-------------CDCHLRWLSSWVKTG---YKEPGIARCAG 895

Query: 209 PNSLQSYNIKTVP-HKAEC 226
           P  ++   + T P  K EC
Sbjct: 896 PQDMEGKLLLTTPAKKFEC 914



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 54/177 (30%), Positives = 75/177 (42%), Gaps = 8/177 (4%)

Query: 47  KDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICR 106
           K + +L L  NQI     +         L  L L  N++ +L    F N  +L  L++  
Sbjct: 85  KQLRVLQLMENQI--GAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSE 142

Query: 107 NSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDVPPLF 166
           N+I  I + AF G   LK L L +N+I  +    F  LR L++L L  N I+ + V    
Sbjct: 143 NAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFN 202

Query: 167 H---LELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNIKTV 220
           H   L    L+ N   C C L  L  WL            T CS P SL+  N+  V
Sbjct: 203 HMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTI---GLFTQCSGPASLRGLNVAEV 256



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 59/208 (28%), Positives = 90/208 (43%), Gaps = 13/208 (6%)

Query: 36  KNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGN 95
           K  T IPA++ + +T + L  N I            Y  L  + L  N++  +  + F  
Sbjct: 298 KGLTAIPANLPETMTEIRLELNGI--KSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG 355

Query: 96  LSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGN 155
           L SL  L +  N I  + +G F GL  L+ L L  NKI  +  D F  L++L LL+L  N
Sbjct: 356 LRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDN 415

Query: 156 LISYL---DVPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSL 212
            I  L       L  ++ + L  N + C C+L  L ++L T+ +         C+ P  L
Sbjct: 416 KIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIETSG---ARCASPRRL 472

Query: 213 QSYNIKTVPHKAECHSKFPSSVTEDLYI 240
            +  I  +  K     KF  S  E  +I
Sbjct: 473 ANKRIGQIKSK-----KFRCSAKEQYFI 495



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 19/61 (31%), Positives = 31/61 (50%)

Query: 100 EILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISY 159
           E L +  N+I  I +  F GL +L+ L L +N+I  +    F  ++ L+ L L  N +  
Sbjct: 64  ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHM 123

Query: 160 L 160
           L
Sbjct: 124 L 124


>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
          Length = 2623

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 61/214 (28%), Positives = 102/214 (47%), Gaps = 31/214 (14%)

Query: 28  EVQCNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFL-LTELYLIENKVT 86
           EV C F  +  T IP  I  +V  ++L YN +       R+++T F  LT+L L+     
Sbjct: 40  EVHCTF--RYLTSIPDSIPPNVERINLGYNSLV------RLMETDFSGLTKLELL----- 86

Query: 87  ILHNNG--------FGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNA 138
           +LH+NG        F +L +L++L +  N +  +Q+  F GL  L +L++  N IE +N 
Sbjct: 87  MLHSNGIHTIPDKTFSDLQALQVLKMSYNKVRKLQKDTFYGLRSLTRLHMDHNNIEFINP 146

Query: 139 DVFVPLRSLKLLNLQGNLISYLDVPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTL 198
           +VF  L  L+L++L+GN ++ L       L  + ++           +   +L  S+  L
Sbjct: 147 EVFYGLNFLRLVHLEGNQLTKLHPDTFVSLSYLQIF---------KISFIKFLYLSDNFL 197

Query: 199 ENENITMCSYPNSLQSYNIKTVPHKAECHSKFPS 232
            +    M SY   L S  +   P   +CH K+ S
Sbjct: 198 TSLPQEMVSYMPDLDSLYLHGNPWTCDCHLKWLS 231


>gi|40217820 slit and trk like 3 protein [Homo sapiens]
          Length = 977

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 68/220 (30%), Positives = 96/220 (43%), Gaps = 10/220 (4%)

Query: 26  KREVQCNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKV 85
           K  +Q N   K YT     +   V+I +L  N   L    T       +L  LYL ENK+
Sbjct: 81  KLYLQRNSMRKLYTNSFLHLNNAVSI-NLGNN--ALQDIQTGAFNGLKILKRLYLHENKL 137

Query: 86  TILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLR 145
            +  N+ F  L SLE L    N I  I+ GAF  L+KL+ L L  N I  L  ++F  + 
Sbjct: 138 DVFRNDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAV- 196

Query: 146 SLKLLNLQGNLISYLDVPPLF-----HLELITLYGNLWNCSCSLFNLQNWLNTSNVTLEN 200
           SL  L+L+GN +  L    +       L  + L  N WNC+C +  L++WL     T   
Sbjct: 197 SLTHLDLRGNRLKVLFYRGMLDHIGRSLMELQLEENPWNCTCEIVQLKSWLERIPYTALV 256

Query: 201 ENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTEDLYI 240
            +IT C  P      +++ +     C     S V   L I
Sbjct: 257 GDIT-CETPFHFHGKDLREIRKTELCPLLSDSEVEASLGI 295



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 57/202 (28%), Positives = 88/202 (43%), Gaps = 54/202 (26%)

Query: 77  ELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL 136
           +LYL  N +  ++ + F N SSL++L++  N I  +Q GAF+ L  LK L+L  N IE+L
Sbjct: 412 KLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKL 471

Query: 137 NADVFVPLRSL------------------------KLLNLQGNLIS-------------- 158
              +F  L+SL                        KLL L  NL+               
Sbjct: 472 TPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLAR 531

Query: 159 ---------YLDVP-PLFHLELIT---LYGNLWNCSCSLFNLQNWLNT-SNVTLENENIT 204
                    YL V   L HL  I    L  N W+C+C L   + W+ T S+V++  +   
Sbjct: 532 LNLRKNYFLYLPVAGVLEHLNAIVQIDLNENPWDCTCDLVPFKQWIETISSVSVVGD--V 589

Query: 205 MCSYPNSLQSYNIKTVPHKAEC 226
           +C  P +L   +++T+  +  C
Sbjct: 590 LCRSPENLTHRDVRTIELEVLC 611



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 16/37 (43%), Positives = 22/37 (59%)

Query: 124 KQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYL 160
           K+LYL  N I+++    F    SL LL+L  N ISY+
Sbjct: 411 KKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYV 447


>gi|40217817 slit and trk like 1 protein [Homo sapiens]
          Length = 696

 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 49/148 (33%), Positives = 70/148 (47%), Gaps = 7/148 (4%)

Query: 47  KDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICR 106
           K++ +LDL  N I     +    +    L  LY+  N +  L    F  L +LE LN+  
Sbjct: 399 KNLILLDLGNNNIAT--VENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEY 456

Query: 107 NSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDV---- 162
           N+I +I  G F  + KL+ L L  N +  L  DVF  + SL  L+L  N   YL V    
Sbjct: 457 NAIQLILPGTFNAMPKLRILILNNNLLRSLPVDVFAGV-SLSKLSLHNNYFMYLPVAGVL 515

Query: 163 PPLFHLELITLYGNLWNCSCSLFNLQNW 190
             L  +  I L+GN W CSC++   + W
Sbjct: 516 DQLTSIIQIDLHGNPWECSCTIVPFKQW 543



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 50/164 (30%), Positives = 72/164 (43%), Gaps = 14/164 (8%)

Query: 74  LLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKI 133
           L+  L++  NK+       F  L  LE L    N +  I  GAF  LNKL+ L L  N I
Sbjct: 107 LVKRLHINNNKIKSFRKQTFLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLI 166

Query: 134 EQLNADVF--VPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGNLWNCSCSLFNL 187
             L A+VF  VP+     L+L+GN +  L    +      +  I L  N W+C+C L +L
Sbjct: 167 STLPANVFQYVPITH---LDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSL 223

Query: 188 QNWLNT--SNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSK 229
           + WL     N  +      +C  P  LQ  ++     +  C  K
Sbjct: 224 KEWLENIPKNALIGR---VVCEAPTRLQGKDLNETTEQDLCPLK 264


>gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]
          Length = 958

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 60/194 (30%), Positives = 96/194 (49%), Gaps = 17/194 (8%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L+L  NK+ +L ++ F  L +LE L +  N I VI+  AF  L+ L+ L L  N + 
Sbjct: 131 LRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLS 190

Query: 135 QL--NADVFVPLRSLKLLNLQGNLISYLDVPPLFHLELIT---LYGNLWNCSCSLFNLQN 189
            L  N   FVPL  L L   +  L+ Y+ +  L H++ +    L  N WNCSC L +L++
Sbjct: 191 SLPNNLFRFVPLTHLDLRGNRLKLLPYVGL--LQHMDKVVELQLEENPWNCSCELISLKD 248

Query: 190 WLNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSS--------VTEDLYIH 241
           WL++ + +    ++ +C  P  L   ++  V  +  C  +  S         ++   Y+H
Sbjct: 249 WLDSISYSALVGDV-VCETPFRLHGRDLDEVSKQELCPRRLISDYEMRPQTPLSTTGYLH 307

Query: 242 FQPIS-NSIFNSSS 254
             P S NS+  SSS
Sbjct: 308 TTPASVNSVATSSS 321



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 38/104 (36%), Positives = 63/104 (60%), Gaps = 3/104 (2%)

Query: 77  ELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL 136
           ++YL EN + ++    F   + L++L++  N I +IQ  AF  L  L++LYL  N+IE+L
Sbjct: 413 KMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERL 472

Query: 137 NADVFVPLRSLKLLNLQGNLISYLD---VPPLFHLELITLYGNL 177
           + ++F  L+SL+ L LQ NLI  +      P+ +L+L+ L  NL
Sbjct: 473 SPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNL 516



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 8/180 (4%)

Query: 51  ILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIY 110
           +L L  N+I++     R       L  LYL  N++  L    F  L SL+ L +  N I 
Sbjct: 437 LLHLGNNRISM--IQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIR 494

Query: 111 VIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDV----PPLF 166
            IQ G F  +  L+ L+L  N ++ + + VF  L  L+ LNL+ N  + L V      L 
Sbjct: 495 EIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLTLLR-LNLRSNHFTSLPVSGVLDQLK 553

Query: 167 HLELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAEC 226
            L  I L+ N W+C+C +  ++ W+    V +  + + +C  P      +++++  +  C
Sbjct: 554 SLIQIDLHDNPWDCTCDIVGMKLWVEQLKVGVLVDEV-ICKAPKKFAETDMRSIKSELLC 612


>gi|10190722 leucine-rich repeats and transmembrane domains 1 [Homo
           sapiens]
          Length = 345

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 53/204 (25%), Positives = 93/204 (45%), Gaps = 7/204 (3%)

Query: 23  QSSKREVQCNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIE 82
           QSS   V C+  ++    IP+ +      L L  NQI  +       ++   L  L L  
Sbjct: 28  QSSTNFVDCS--QQGLAEIPSHLPPQTRTLHLQDNQI--HHLPAFAFRSVPWLMTLNLSN 83

Query: 83  NKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFV 142
           N ++ L    F  L  L++LN+ +NS+  ++   F  L +L++L L  N I  L   +  
Sbjct: 84  NSLSNLAPGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNISHLPTSLGE 143

Query: 143 PLRSLKLLNLQGNLISYLD---VPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTLE 199
              +L +L +Q N +  LD   +  +  + L+ L  NLW C+C L  L+ WL        
Sbjct: 144 TWENLTILAVQQNQLQQLDRALLESMPSVRLLLLKDNLWKCNCHLLGLKLWLEKFVYKGG 203

Query: 200 NENITMCSYPNSLQSYNIKTVPHK 223
             +  +C  P++ +  ++  +PH+
Sbjct: 204 LTDGIICESPDTWKGKDLLRIPHE 227


>gi|27436867 slit and trk like 4 protein [Homo sapiens]
          Length = 837

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 60/233 (25%), Positives = 100/233 (42%), Gaps = 28/233 (12%)

Query: 21  KIQSSKREVQCNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYL 80
           K   S   +  N  EKN   +   I K +    L  N  ++   D      +  L  L+L
Sbjct: 349 KTHPSDLGLSVNCQEKNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHL 408

Query: 81  IENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADV 140
             N++T++  + F NL++L  L +  N I  +    F GL+ L+ LYL  N I++++A  
Sbjct: 409 GSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGT 468

Query: 141 FVPLRSLKLLNLQGNLISYLDV-----PPLFHLEL----------------------ITL 173
           F  + +L+LL L  NL+  L V      PL  L L                      I L
Sbjct: 469 FDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDL 528

Query: 174 YGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAEC 226
            GN W+C+C L  L+ W+   +  +  + +  C  P    +  +K++ ++  C
Sbjct: 529 EGNPWDCTCDLVALKLWVEKLSDGIVVKEL-KCETPVQFANIELKSLKNEILC 580



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 60/202 (29%), Positives = 93/202 (46%), Gaps = 16/202 (7%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L +L+L  N++ IL  + F  + +LE L    N I  I++GAF  L+KLK L L  N I 
Sbjct: 109 LKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLIS 168

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLD-VPPLFHLELIT---LYGNLWNCSCSLFNLQNW 190
            L  ++F    SL  L+++GN I  L  +  L H+  +    L  N WNCSC L  L+ W
Sbjct: 169 FLPDNIF-RFASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAW 227

Query: 191 LNTS--NVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTEDLYIHFQPIS-- 246
           L     N+ +      +C  P+ L    +K    +  C    P     D  +   P S  
Sbjct: 228 LENMPYNIYIGE---AICETPSDLYGRLLKETNKQELC----PMGTGSDFDVRILPPSQL 280

Query: 247 NSIFNSSSNNLTRNSEHEPLGK 268
            + + + + + T+ S H  + K
Sbjct: 281 ENGYTTPNGHTTQTSLHRLVTK 302


>gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 54/166 (32%), Positives = 78/166 (46%), Gaps = 8/166 (4%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L+L  NK+ IL  + F  L SLE L    N I  I+ GAF  LNKLK L L  N + 
Sbjct: 112 LKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLL 171

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGNLWNCSCSLFNLQNW 190
            L ++VF     L  L+L+GN +  +    +      +  I L  N WNC+C L  L+ W
Sbjct: 172 SLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAW 230

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTE 236
           L+T  V +      +C  P  L   ++  +  +  C  K  S  ++
Sbjct: 231 LDTITVFVGE---IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQ 273



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 52/201 (25%), Positives = 83/201 (41%), Gaps = 52/201 (25%)

Query: 77  ELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL 136
           +LYL  N +  ++ N     SSL++L++  N I VIQ+GAF  L  L++LYL  N +E L
Sbjct: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438

Query: 137 NADVFVPLRSLKLLNLQGNLISY---LDVPPLFHLELITLYGNL---------------- 177
              +F  L+SL+ L L+ N+I     L    L +L+L+ L  NL                
Sbjct: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTR 498

Query: 178 --------------------------------WNCSCSLFNLQNWLNTSNVTLENENITM 205
                                           W+C+C +  L++W   +N  +    +T 
Sbjct: 499 LNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVT- 557

Query: 206 CSYPNSLQSYNIKTVPHKAEC 226
           C  P       +K +  +A C
Sbjct: 558 CESPAKHAGEILKFLGREAIC 578


>gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 54/166 (32%), Positives = 78/166 (46%), Gaps = 8/166 (4%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L+L  NK+ IL  + F  L SLE L    N I  I+ GAF  LNKLK L L  N + 
Sbjct: 112 LKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLL 171

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGNLWNCSCSLFNLQNW 190
            L ++VF     L  L+L+GN +  +    +      +  I L  N WNC+C L  L+ W
Sbjct: 172 SLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAW 230

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTE 236
           L+T  V +      +C  P  L   ++  +  +  C  K  S  ++
Sbjct: 231 LDTITVFVGE---IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQ 273



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 52/201 (25%), Positives = 83/201 (41%), Gaps = 52/201 (25%)

Query: 77  ELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL 136
           +LYL  N +  ++ N     SSL++L++  N I VIQ+GAF  L  L++LYL  N +E L
Sbjct: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438

Query: 137 NADVFVPLRSLKLLNLQGNLISY---LDVPPLFHLELITLYGNL---------------- 177
              +F  L+SL+ L L+ N+I     L    L +L+L+ L  NL                
Sbjct: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTR 498

Query: 178 --------------------------------WNCSCSLFNLQNWLNTSNVTLENENITM 205
                                           W+C+C +  L++W   +N  +    +T 
Sbjct: 499 LNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVT- 557

Query: 206 CSYPNSLQSYNIKTVPHKAEC 226
           C  P       +K +  +A C
Sbjct: 558 CESPAKHAGEILKFLGREAIC 578


>gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 54/166 (32%), Positives = 78/166 (46%), Gaps = 8/166 (4%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L+L  NK+ IL  + F  L SLE L    N I  I+ GAF  LNKLK L L  N + 
Sbjct: 112 LKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLL 171

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGNLWNCSCSLFNLQNW 190
            L ++VF     L  L+L+GN +  +    +      +  I L  N WNC+C L  L+ W
Sbjct: 172 SLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAW 230

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTE 236
           L+T  V +      +C  P  L   ++  +  +  C  K  S  ++
Sbjct: 231 LDTITVFVGE---IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQ 273



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 52/201 (25%), Positives = 83/201 (41%), Gaps = 52/201 (25%)

Query: 77  ELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL 136
           +LYL  N +  ++ N     SSL++L++  N I VIQ+GAF  L  L++LYL  N +E L
Sbjct: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438

Query: 137 NADVFVPLRSLKLLNLQGNLISY---LDVPPLFHLELITLYGNL---------------- 177
              +F  L+SL+ L L+ N+I     L    L +L+L+ L  NL                
Sbjct: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTR 498

Query: 178 --------------------------------WNCSCSLFNLQNWLNTSNVTLENENITM 205
                                           W+C+C +  L++W   +N  +    +T 
Sbjct: 499 LNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVT- 557

Query: 206 CSYPNSLQSYNIKTVPHKAEC 226
           C  P       +K +  +A C
Sbjct: 558 CESPAKHAGEILKFLGREAIC 578


>gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 54/166 (32%), Positives = 78/166 (46%), Gaps = 8/166 (4%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L+L  NK+ IL  + F  L SLE L    N I  I+ GAF  LNKLK L L  N + 
Sbjct: 112 LKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLL 171

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGNLWNCSCSLFNLQNW 190
            L ++VF     L  L+L+GN +  +    +      +  I L  N WNC+C L  L+ W
Sbjct: 172 SLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAW 230

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTE 236
           L+T  V +      +C  P  L   ++  +  +  C  K  S  ++
Sbjct: 231 LDTITVFVGE---IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQ 273



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 52/201 (25%), Positives = 83/201 (41%), Gaps = 52/201 (25%)

Query: 77  ELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL 136
           +LYL  N +  ++ N     SSL++L++  N I VIQ+GAF  L  L++LYL  N +E L
Sbjct: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438

Query: 137 NADVFVPLRSLKLLNLQGNLISY---LDVPPLFHLELITLYGNL---------------- 177
              +F  L+SL+ L L+ N+I     L    L +L+L+ L  NL                
Sbjct: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTR 498

Query: 178 --------------------------------WNCSCSLFNLQNWLNTSNVTLENENITM 205
                                           W+C+C +  L++W   +N  +    +T 
Sbjct: 499 LNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVT- 557

Query: 206 CSYPNSLQSYNIKTVPHKAEC 226
           C  P       +K +  +A C
Sbjct: 558 CESPAKHAGEILKFLGREAIC 578


>gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 54/166 (32%), Positives = 78/166 (46%), Gaps = 8/166 (4%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L+L  NK+ IL  + F  L SLE L    N I  I+ GAF  LNKLK L L  N + 
Sbjct: 112 LKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLL 171

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGNLWNCSCSLFNLQNW 190
            L ++VF     L  L+L+GN +  +    +      +  I L  N WNC+C L  L+ W
Sbjct: 172 SLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAW 230

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTE 236
           L+T  V +      +C  P  L   ++  +  +  C  K  S  ++
Sbjct: 231 LDTITVFVGE---IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQ 273



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 52/201 (25%), Positives = 83/201 (41%), Gaps = 52/201 (25%)

Query: 77  ELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL 136
           +LYL  N +  ++ N     SSL++L++  N I VIQ+GAF  L  L++LYL  N +E L
Sbjct: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438

Query: 137 NADVFVPLRSLKLLNLQGNLISY---LDVPPLFHLELITLYGNL---------------- 177
              +F  L+SL+ L L+ N+I     L    L +L+L+ L  NL                
Sbjct: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTR 498

Query: 178 --------------------------------WNCSCSLFNLQNWLNTSNVTLENENITM 205
                                           W+C+C +  L++W   +N  +    +T 
Sbjct: 499 LNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVT- 557

Query: 206 CSYPNSLQSYNIKTVPHKAEC 226
           C  P       +K +  +A C
Sbjct: 558 CESPAKHAGEILKFLGREAIC 578


>gi|221136965 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 54/166 (32%), Positives = 78/166 (46%), Gaps = 8/166 (4%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L+L  NK+ IL  + F  L SLE L    N I  I+ GAF  LNKLK L L  N + 
Sbjct: 112 LKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLL 171

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGNLWNCSCSLFNLQNW 190
            L ++VF     L  L+L+GN +  +    +      +  I L  N WNC+C L  L+ W
Sbjct: 172 SLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAW 230

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTE 236
           L+T  V +      +C  P  L   ++  +  +  C  K  S  ++
Sbjct: 231 LDTITVFVGE---IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQ 273



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 52/201 (25%), Positives = 83/201 (41%), Gaps = 52/201 (25%)

Query: 77  ELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL 136
           +LYL  N +  ++ N     SSL++L++  N I VIQ+GAF  L  L++LYL  N +E L
Sbjct: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438

Query: 137 NADVFVPLRSLKLLNLQGNLISY---LDVPPLFHLELITLYGNL---------------- 177
              +F  L+SL+ L L+ N+I     L    L +L+L+ L  NL                
Sbjct: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTR 498

Query: 178 --------------------------------WNCSCSLFNLQNWLNTSNVTLENENITM 205
                                           W+C+C +  L++W   +N  +    +T 
Sbjct: 499 LNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVT- 557

Query: 206 CSYPNSLQSYNIKTVPHKAEC 226
           C  P       +K +  +A C
Sbjct: 558 CESPAKHAGEILKFLGREAIC 578


>gi|221136961 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 54/166 (32%), Positives = 78/166 (46%), Gaps = 8/166 (4%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L+L  NK+ IL  + F  L SLE L    N I  I+ GAF  LNKLK L L  N + 
Sbjct: 112 LKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLL 171

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGNLWNCSCSLFNLQNW 190
            L ++VF     L  L+L+GN +  +    +      +  I L  N WNC+C L  L+ W
Sbjct: 172 SLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAW 230

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTE 236
           L+T  V +      +C  P  L   ++  +  +  C  K  S  ++
Sbjct: 231 LDTITVFVGE---IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQ 273



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 52/201 (25%), Positives = 83/201 (41%), Gaps = 52/201 (25%)

Query: 77  ELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL 136
           +LYL  N +  ++ N     SSL++L++  N I VIQ+GAF  L  L++LYL  N +E L
Sbjct: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438

Query: 137 NADVFVPLRSLKLLNLQGNLISY---LDVPPLFHLELITLYGNL---------------- 177
              +F  L+SL+ L L+ N+I     L    L +L+L+ L  NL                
Sbjct: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTR 498

Query: 178 --------------------------------WNCSCSLFNLQNWLNTSNVTLENENITM 205
                                           W+C+C +  L++W   +N  +    +T 
Sbjct: 499 LNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVT- 557

Query: 206 CSYPNSLQSYNIKTVPHKAEC 226
           C  P       +K +  +A C
Sbjct: 558 CESPAKHAGEILKFLGREAIC 578


>gi|221136957 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 54/166 (32%), Positives = 78/166 (46%), Gaps = 8/166 (4%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L+L  NK+ IL  + F  L SLE L    N I  I+ GAF  LNKLK L L  N + 
Sbjct: 112 LKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLL 171

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGNLWNCSCSLFNLQNW 190
            L ++VF     L  L+L+GN +  +    +      +  I L  N WNC+C L  L+ W
Sbjct: 172 SLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAW 230

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTE 236
           L+T  V +      +C  P  L   ++  +  +  C  K  S  ++
Sbjct: 231 LDTITVFVGE---IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQ 273



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 52/201 (25%), Positives = 83/201 (41%), Gaps = 52/201 (25%)

Query: 77  ELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL 136
           +LYL  N +  ++ N     SSL++L++  N I VIQ+GAF  L  L++LYL  N +E L
Sbjct: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438

Query: 137 NADVFVPLRSLKLLNLQGNLISY---LDVPPLFHLELITLYGNL---------------- 177
              +F  L+SL+ L L+ N+I     L    L +L+L+ L  NL                
Sbjct: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTR 498

Query: 178 --------------------------------WNCSCSLFNLQNWLNTSNVTLENENITM 205
                                           W+C+C +  L++W   +N  +    +T 
Sbjct: 499 LNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVT- 557

Query: 206 CSYPNSLQSYNIKTVPHKAEC 226
           C  P       +K +  +A C
Sbjct: 558 CESPAKHAGEILKFLGREAIC 578


>gi|33504581 SLIT and NTRK-like family, member 2 [Homo sapiens]
          Length = 845

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 54/166 (32%), Positives = 78/166 (46%), Gaps = 8/166 (4%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           L  L+L  NK+ IL  + F  L SLE L    N I  I+ GAF  LNKLK L L  N + 
Sbjct: 112 LKRLHLNNNKLEILREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLL 171

Query: 135 QLNADVFVPLRSLKLLNLQGNLISYLDVPPLFH----LELITLYGNLWNCSCSLFNLQNW 190
            L ++VF     L  L+L+GN +  +    +      +  I L  N WNC+C L  L+ W
Sbjct: 172 SLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNCTCDLLPLKAW 230

Query: 191 LNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTE 236
           L+T  V +      +C  P  L   ++  +  +  C  K  S  ++
Sbjct: 231 LDTITVFVGE---IVCETPFRLHGKDVTQLTRQDLCPRKSASDSSQ 273



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 52/201 (25%), Positives = 83/201 (41%), Gaps = 52/201 (25%)

Query: 77  ELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL 136
           +LYL  N +  ++ N     SSL++L++  N I VIQ+GAF  L  L++LYL  N +E L
Sbjct: 379 KLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVL 438

Query: 137 NADVFVPLRSLKLLNLQGNLISY---LDVPPLFHLELITLYGNL---------------- 177
              +F  L+SL+ L L+ N+I     L    L +L+L+ L  NL                
Sbjct: 439 YPSMFDGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTR 498

Query: 178 --------------------------------WNCSCSLFNLQNWLNTSNVTLENENITM 205
                                           W+C+C +  L++W   +N  +    +T 
Sbjct: 499 LNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDCTCDIMGLKDWTEHANSPVIINEVT- 557

Query: 206 CSYPNSLQSYNIKTVPHKAEC 226
           C  P       +K +  +A C
Sbjct: 558 CESPAKHAGEILKFLGREAIC 578


>gi|198041768 synleurin [Homo sapiens]
          Length = 622

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 66/226 (29%), Positives = 92/226 (40%), Gaps = 66/226 (29%)

Query: 51  ILDLSYNQITLNGTDTRVLQTYFLLTE----LYLIENKVTILHNNGFGNLSSLEILNICR 106
           ILDLS N I       R+ ++ F   E    LYL  N +T + +N F  L SL  L++  
Sbjct: 184 ILDLSNNNIL------RISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSH 237

Query: 107 NSIYVIQQGAFLGL------------------------NKLKQLYLCQNKIEQLNADVFV 142
           N I  IQ  AF GL                        N LK L L  N +E LN+D F 
Sbjct: 238 NPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFS 297

Query: 143 PLR-------------------------SLKLLNLQGNLISYLD---VPPLFHLELITLY 174
            L+                         SLK+LNL  N ++ L    + PL  L  +   
Sbjct: 298 LLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQAN 357

Query: 175 GNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNIKTV 220
            N W C+C L  L++WL +S +TL       C  P S++   ++ +
Sbjct: 358 SNPWECNCKLLGLRDWLASSAITLN----IYCQNPPSMRGRALRYI 399



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 39/132 (29%), Positives = 62/132 (46%), Gaps = 4/132 (3%)

Query: 30  QCNFTEKNYTLIPADIKKDVTILDLSYNQIT-LNGTDTRVLQTYFLLTELYLIENKVTIL 88
           Q N      + IP +  +    L L+ N I+ +N ++   L +   L  LYL  + +  +
Sbjct: 43  QINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHS---LVALYLDNSNILYV 99

Query: 89  HNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLK 148
           +   F  L  L  L +  N I  +  G F GL  L+ LYL  N++  +   VF  L S++
Sbjct: 100 YPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQ 159

Query: 149 LLNLQGNLISYL 160
            LNLQ N ++ L
Sbjct: 160 YLNLQRNRLTVL 171



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 33/106 (31%), Positives = 54/106 (50%), Gaps = 2/106 (1%)

Query: 52  LDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYV 111
           L L YNQ++       V      +  L L  N++T+L +  F  + +L IL++  N+I  
Sbjct: 137 LYLQYNQVSF--VPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILR 194

Query: 112 IQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLI 157
           I +  F  L  L  LYL  N + ++ ++ F  L+SL+ L+L  N I
Sbjct: 195 ISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPI 240



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 31/102 (30%), Positives = 50/102 (49%)

Query: 54  LSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQ 113
           L  N   +   D  + +    L  LYL  N+V+ +    F +L S++ LN+ RN + V+ 
Sbjct: 113 LFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLG 172

Query: 114 QGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGN 155
            G F+G+  L+ L L  N I +++   F  L +L  L L  N
Sbjct: 173 SGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSN 214


>gi|4759146 slit homolog 2 [Homo sapiens]
          Length = 1529

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 61/212 (28%), Positives = 91/212 (42%), Gaps = 42/212 (19%)

Query: 41  IPADIKKDVTILDLSYNQITLNGTDTRVLQTYFL----LTELYLIENKVTILHNNGFGNL 96
           +P +I ++   LDL+ N IT      R+ +T F     L  L L+ENK++ +    F +L
Sbjct: 49  VPRNIPRNTERLDLNGNNIT------RITKTDFAGLRHLRVLQLMENKISTIERGAFQDL 102

Query: 97  SSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQ--------------------- 135
             LE L + RN + +  +  FLG  KL +L L +N+I+                      
Sbjct: 103 KELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQ 162

Query: 136 ---LNADVFVPLRSLKLLNLQGNLISYLDVPPLFH---LELITLYGNLWNCSCSLFNLQN 189
              +    F  LR L++L L  N I+ L V    H   L    L+ N   C C L  L +
Sbjct: 163 ISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSD 222

Query: 190 WL-NTSNVTLENENITMCSYPNSLQSYNIKTV 220
           WL     V L     T C  P+ L+ +N+  V
Sbjct: 223 WLRQRPRVGL----YTQCMGPSHLRGHNVAEV 250



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 58/208 (27%), Positives = 90/208 (43%), Gaps = 13/208 (6%)

Query: 36  KNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGN 95
           K  T IP ++ + +T + L  N  T+          Y  L  + L  N+++ L  + F  
Sbjct: 289 KGLTEIPTNLPETITEIRLEQN--TIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQG 346

Query: 96  LSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGN 155
           L SL  L +  N I  + +  F GL  L+ L L  NKI  L  D F  L +L LL+L  N
Sbjct: 347 LRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDN 406

Query: 156 LISYL---DVPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSL 212
            +  +      PL  ++ + L  N + C C L  L ++L+T+ +         C+ P  L
Sbjct: 407 KLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIETSG---ARCTSPRRL 463

Query: 213 QSYNIKTVPHKAECHSKFPSSVTEDLYI 240
            +  I  +  K     KF  S  E  +I
Sbjct: 464 ANKRIGQIKSK-----KFRCSAKEQYFI 486



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 51/172 (29%), Positives = 72/172 (41%), Gaps = 31/172 (18%)

Query: 77  ELYLIENKVTILHNNG-FGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQ 135
           EL L  N+ T+L   G F  L  L  +N   N I  I++GAF G + + ++ L  N++E 
Sbjct: 537 ELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLEN 596

Query: 136 LNADVFVPLRSLKLLNLQGN-----------------LISYLD-----VPP-----LFHL 168
           +   +F  L SLK L L+ N                 L+S  D     V P     L  L
Sbjct: 597 VQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSL 656

Query: 169 ELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNIKTV 220
             + L  N +NC+C L  L  WL    +   N     C  P  L+   I+ V
Sbjct: 657 STLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPR---CQKPYFLKEIPIQDV 705



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 53/195 (27%), Positives = 81/195 (41%), Gaps = 29/195 (14%)

Query: 29  VQCNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTIL 88
           V+C+   K   ++P  I +DVT L L  NQ TL   +   L  Y  LT + L  N+++ L
Sbjct: 738 VRCS--NKGLKVLPKGIPRDVTELYLDGNQFTLVPKE---LSNYKHLTLIDLSNNRISTL 792

Query: 89  HNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLK 148
            N  F N++ L  L +  N +  I    F GL  L+ L L  N I  +    F  L +L 
Sbjct: 793 SNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALS 852

Query: 149 LLNLQGNLISYLDVPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSY 208
            L +  N        PL+             C C++  L +W+ +     +   I  C+ 
Sbjct: 853 HLAIGAN--------PLY-------------CDCNMQWLSDWVKSE---YKEPGIARCAG 888

Query: 209 PNSLQSYNIKTVPHK 223
           P  +    + T P K
Sbjct: 889 PGEMADKLLLTTPSK 903


>gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens]
          Length = 522

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 57/187 (30%), Positives = 86/187 (45%), Gaps = 35/187 (18%)

Query: 34  TEKNYTLIPADIKKDVTILDLSYNQITLNGTD-----------------------TRVLQ 70
           T KN + +P ++ + +  LDLSYN+I L  ++                       T    
Sbjct: 55  TNKNLSKVPGNLFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSFS 114

Query: 71  TYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQ 130
           T   L  L L  NK+  + N  F  L  LE+L +  N I  +   AF GL++L++LYL  
Sbjct: 115 TTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSG 174

Query: 131 NKIEQLNADVFVPLRSLKLLNLQGNLISYLDVP--PLFHLEL--------ITLYGNLWNC 180
           N + Q   D++V     KL  L    +SY  +P  P+ H+ L        I L+GN + C
Sbjct: 175 NFLTQFPMDLYV--GRFKLAELMFLDVSYNRIPSMPMHHINLVPGKQLRGIYLHGNPFVC 232

Query: 181 SCSLFNL 187
            CSL++L
Sbjct: 233 DCSLYSL 239


>gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens]
          Length = 522

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 57/187 (30%), Positives = 86/187 (45%), Gaps = 35/187 (18%)

Query: 34  TEKNYTLIPADIKKDVTILDLSYNQITLNGTD-----------------------TRVLQ 70
           T KN + +P ++ + +  LDLSYN+I L  ++                       T    
Sbjct: 55  TNKNLSKVPGNLFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSFS 114

Query: 71  TYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQ 130
           T   L  L L  NK+  + N  F  L  LE+L +  N I  +   AF GL++L++LYL  
Sbjct: 115 TTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSG 174

Query: 131 NKIEQLNADVFVPLRSLKLLNLQGNLISYLDVP--PLFHLEL--------ITLYGNLWNC 180
           N + Q   D++V     KL  L    +SY  +P  P+ H+ L        I L+GN + C
Sbjct: 175 NFLTQFPMDLYV--GRFKLAELMFLDVSYNRIPSMPMHHINLVPGKQLRGIYLHGNPFVC 232

Query: 181 SCSLFNL 187
            CSL++L
Sbjct: 233 DCSLYSL 239


>gi|150417978 platelet glycoprotein Ib alpha polypeptide precursor
           [Homo sapiens]
          Length = 639

 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 61/240 (25%), Positives = 102/240 (42%), Gaps = 53/240 (22%)

Query: 24  SSKREVQCNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIEN 83
           +S  EV C+  ++N T +P D+ KD TIL LS N +      T  L  Y  LT+L L   
Sbjct: 26  ASHLEVNCD--KRNLTALPPDLPKDTTILHLSENLLYTFSLAT--LMPYTRLTQLNLDRC 81

Query: 84  KVTILHNNGF---------------------GNLSSLEILNICRNSIYVIQQGAFLGLNK 122
           ++T L  +G                        L +L +L++  N +  +  GA  GL +
Sbjct: 82  ELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGE 141

Query: 123 LKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDVPPLFHLELIT---------- 172
           L++LYL  N+++ L   +  P   L+ L+L  N ++ L    L  LE +           
Sbjct: 142 LQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLY 201

Query: 173 ----------------LYGNLWNCSCSLFNLQNWL--NTSNVTLENENITMCSYPNSLQS 214
                           L+GN W C+C +   + WL  N  NV +  + + + +  +++ S
Sbjct: 202 TIPKGFFGSHLLPFAFLHGNPWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVAS 261


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 52/183 (28%), Positives = 85/183 (46%), Gaps = 7/183 (3%)

Query: 41  IPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLE 100
           IP+ + + VT L L+ N++++    T + +    L ++ L  NK+  +    F   +S++
Sbjct: 526 IPSHLPEYVTDLRLNDNEVSVLEA-TGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQ 584

Query: 101 ILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYL 160
            L +  N +  +    F GL+ LK L L  N I  ++ D F  L S++LL+L  N I+ +
Sbjct: 585 ELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTI 644

Query: 161 D---VPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNI 217
                  L  L  I L  N +NC+C L  L  WL    +   N     C  P  L+   I
Sbjct: 645 TPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPR---CQKPFFLKEIPI 701

Query: 218 KTV 220
           + V
Sbjct: 702 QDV 704



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 49/159 (30%), Positives = 74/159 (46%), Gaps = 14/159 (8%)

Query: 75  LTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIE 134
           +TELYL  N +T +       L  L ++++  NSI ++    F  ++ L  L L  N++ 
Sbjct: 754 VTELYLEGNHLTAVPRE-LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLR 812

Query: 135 QLNADVFVPLRSLKLLNLQGNLI------SYLDVPPLFHLELITLYGNLWNCSCSLFNLQ 188
            +    F  LRSL++L L GN I      S+ D+  L HL L T   N  +C CSL  L 
Sbjct: 813 CIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGT---NPLHCDCSLRWLS 869

Query: 189 NWLNTSNVTLENENITMCSYPNSLQSYNIKTVP-HKAEC 226
            W+       +   I  CS P  +    + T P H+ +C
Sbjct: 870 EWVKAG---YKEPGIARCSSPEPMADRLLLTTPTHRFQC 905



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 56/205 (27%), Positives = 89/205 (43%), Gaps = 13/205 (6%)

Query: 41  IPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLE 100
           IPA++ + +  + L  N I            Y  L  + + +N+++ +  + F  L SL 
Sbjct: 301 IPANLPEGIVEIRLEQNSI--KAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLT 358

Query: 101 ILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYL 160
            L +  N I  I +G F GL  L+ L L  NKI  L  + F  L++L LL+L  N +  +
Sbjct: 359 SLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTI 418

Query: 161 D---VPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNI 217
                 PL  ++ + L  N + C C L  L ++L  + +         CS P  L +  I
Sbjct: 419 SKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSG---ARCSSPRRLANKRI 475

Query: 218 KTVPHKAECHSKFPSSVTEDLYIHF 242
             +  K     KF  S +ED    F
Sbjct: 476 SQIKSK-----KFRCSGSEDYRSRF 495



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 51/210 (24%), Positives = 78/210 (37%), Gaps = 58/210 (27%)

Query: 78  LYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQL- 136
           L L  N +T +    F  L +L +L++  N + VI++GAF  L +L++L L +NK++ L 
Sbjct: 66  LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125

Query: 137 -----------------------------------------------NADVFVPLRSLKL 149
                                                              F  LR L++
Sbjct: 126 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 185

Query: 150 LNLQGNLISYLDVPPLFH---LELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMC 206
           L L  N IS + V    H   +  + L+ N   C C L  L +WL            T+C
Sbjct: 186 LTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTV---GQFTLC 242

Query: 207 SYPNSLQSYNIKTVPHKAEC----HSKFPS 232
             P  L+ +N+  V  K       HS+ PS
Sbjct: 243 MAPVHLRGFNVADVQKKEYVCPAPHSEPPS 272



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 49  VTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNS 108
           +T LDLS NQI   G   +  +    +  L L  N ++ + +  F  L  LEIL +  N+
Sbjct: 135 LTRLDLSENQI--QGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNN 192

Query: 109 IYVIQQGAFLGLNKLKQLYLCQNKI 133
           I  I   +F  + K++ L L  N +
Sbjct: 193 ISRILVTSFNHMPKIRTLRLHSNHL 217



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 6/77 (7%)

Query: 100 EILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISY 159
           E L++ RN+I  I +  F GL  L+ L+L  N++  +    F  L+ L+ L L  N +  
Sbjct: 64  ERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQV 123

Query: 160 L------DVPPLFHLEL 170
           L        P L  L+L
Sbjct: 124 LPELLFQSTPKLTRLDL 140


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,337,228
Number of Sequences: 37866
Number of extensions: 564294
Number of successful extensions: 2529
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 149
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 1591
Number of HSP's gapped (non-prelim): 689
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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