Guide to the Human Genome
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Name: HFE2 Sequence: fasta or formatted (200aa) NCBI GI: 42544157
Description:

hemojuvelin isoform c

Referenced in:

Iron, Copper, and Arsenic Metabolism

Other entries for this name:
alt prot [313aa] hemojuvelin isoform b
alt prot [426aa] hemojuvelin isoform a precursor
alt mRNA [200aa] hemojuvelin isoform c
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.0         22           2
 C cysteine            3.0          6           1
 D aspartate           6.5         13           1
 E glutamate           5.5         11           1
 F phenylalanine       4.5          9           1
 G glycine             7.5         15           2
 H histidine           1.5          3           1
 I isoleucine          6.5         13           3
 K lysine              2.0          4           1
 L leucine            11.0         22           2
 M methionine          1.0          2           1
 N asparagine          3.0          6           1
 P proline             5.5         11           2
 Q glutamine           6.0         12           1
 R arginine            5.0         10           2
 S serine              8.0         16           2
 T threonine           4.0          8           2
 V valine              6.5         13           1
 W tryptophan          0.5          1           1
 Y tyrosine            1.5          3           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hemojuvelin isoform c 
HFE2                  1.000   hemojuvelin isoform b 
HFE2                  1.000   hemojuvelin isoform c 
HFE2                  1.000   hemojuvelin isoform a precursor 
RGMB                  0.377   RGM domain family, member B 
RGMA                  0.374   RGM domain family, member A 
ACTL9                 0.013   actin-like 9 
DDX21                 0.013   DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 
LOC285556             0.011   PREDICTED: hypothetical protein LOC285556 
LOC285556             0.011   PREDICTED: hypothetical protein LOC285556 
LOC285556             0.011   PREDICTED: hypothetical protein LOC285556 
SMG1                  0.008   PI-3-kinase-related kinase SMG-1 
MED12                 0.008   mediator complex subunit 12 
CMPK2                 0.008   UMP-CMP kinase 2 
ATP10D                0.008   ATPase, class V, type 10D 
C14orf177             0.008   hypothetical protein LOC283598 
HUWE1                 0.005   HECT, UBA and WWE domain containing 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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