Search of human proteins with 42490760

Search of human proteins with 42490760

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42490760 cell division cycle 25A isoform b [Homo sapiens]
         (484 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42490760 cell division cycle 25A isoform b [Homo sapiens]          993   0.0  
gi|42490758 cell division cycle 25A isoform a [Homo sapiens]          973   0.0  
gi|4757950 cell division cycle 25B isoform 2 [Homo sapiens]           375   e-104
gi|11641413 cell division cycle 25B isoform 1 [Homo sapiens]          374   e-104
gi|11641411 cell division cycle 25B isoform 3 [Homo sapiens]          373   e-103
gi|125625350 cell division cycle 25C isoform a [Homo sapiens]         262   6e-70
gi|12408658 cell division cycle 25C isoform b [Homo sapiens]          255   5e-68
gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo ...    48   2e-05
gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo ...    48   2e-05
gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo s...    48   2e-05
gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]                     40   0.006
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]     37   0.040
gi|40538736 RAN binding protein 10 [Homo sapiens]                      36   0.068
gi|9257222 forkhead box O1 [Homo sapiens]                              35   0.15 
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                34   0.26 
gi|162287219 prune homolog 2 [Homo sapiens]                            33   0.76 
gi|169179759 PREDICTED: hypothetical protein [Homo sapiens]            32   0.99 
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    32   0.99 
gi|21361348 UTP14, U3 small nucleolar ribonucleoprotein, homolog...    32   0.99 
gi|169180158 PREDICTED: hypothetical protein [Homo sapiens]            32   1.3  
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa...    32   1.3  
gi|33356547 minichromosome maintenance complex component 2 [Homo...    32   1.7  
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    32   1.7  
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    31   2.2  
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]    31   2.2  
gi|22748641 CHMP family, member 7 [Homo sapiens]                       31   2.2  
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]             31   2.9  
gi|169183882 PREDICTED: hypothetical protein [Homo sapiens]            31   2.9  
gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapi...    31   2.9  
gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sap...    31   2.9  

>gi|42490760 cell division cycle 25A isoform b [Homo sapiens]
          Length = 484

 Score =  993 bits (2567), Expect = 0.0
 Identities = 484/484 (100%), Positives = 484/484 (100%)

Query: 1   MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE 60
           MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE
Sbjct: 1   MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE 60

Query: 61  QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK 120
           QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK
Sbjct: 61  QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK 120

Query: 121 RSHSDSLDHDIFQLIDPDENKENLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVD 180
           RSHSDSLDHDIFQLIDPDENKENLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVD
Sbjct: 121 RSHSDSLDHDIFQLIDPDENKENLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVD 180

Query: 181 LLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQ 240
           LLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQ
Sbjct: 181 LLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQ 240

Query: 241 EESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGD 300
           EESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGD
Sbjct: 241 EESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGD 300

Query: 301 FSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAV 360
           FSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAV
Sbjct: 301 FSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAV 360

Query: 361 NLHMEEEVEDFLLKKPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHY 420
           NLHMEEEVEDFLLKKPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHY
Sbjct: 361 NLHMEEEVEDFLLKKPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHY 420

Query: 421 PELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSR 480
           PELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSR
Sbjct: 421 PELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSR 480

Query: 481 LKKL 484
           LKKL
Sbjct: 481 LKKL 484


>gi|42490758 cell division cycle 25A isoform a [Homo sapiens]
          Length = 524

 Score =  973 bits (2516), Expect = 0.0
 Identities = 484/524 (92%), Positives = 484/524 (92%), Gaps = 40/524 (7%)

Query: 1   MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE 60
           MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE
Sbjct: 1   MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE 60

Query: 61  QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK 120
           QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK
Sbjct: 61  QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK 120

Query: 121 RSHSDSLDHDIFQLIDPDENKEN------------------------------------- 143
           RSHSDSLDHDIFQLIDPDENKEN                                     
Sbjct: 121 RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP 180

Query: 144 ---LSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL 200
              LSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL
Sbjct: 181 ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL 240

Query: 201 WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK 260
           WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK
Sbjct: 241 WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK 300

Query: 261 ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI 320
           ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI
Sbjct: 301 ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI 360

Query: 321 SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT 380
           SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT
Sbjct: 361 SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT 420

Query: 381 DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY 440
           DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY
Sbjct: 421 DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY 480

Query: 441 CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL 484
           CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
Sbjct: 481 CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL 524


>gi|4757950 cell division cycle 25B isoform 2 [Homo sapiens]
          Length = 566

 Score =  375 bits (963), Expect = e-104
 Identities = 226/525 (43%), Positives = 302/525 (57%), Gaps = 84/525 (16%)

Query: 36  AGGLSPVTNLTVTMDQLQGLGSDYEQP---LEVKNNSNLQRMGSSESTDSGFCLDSPGPL 92
           A   SPVT LT TM  L GLGS        L  + + +     SSES+D+G C+DSP P+
Sbjct: 46  AAASSPVTTLTQTMHDLAGLGSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPM 105

Query: 93  DSK-----------------ENLENPMRRIHSLPQKLLGCSPALKR-------------- 121
           D                    N +  +RR  S+P +LLG SP L+               
Sbjct: 106 DPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSE 165

Query: 122 -------SHSDSLDHDIFQLIDPDENKENLSSN-------------ERDSSEPG------ 155
                  S  +  ++D F    P +     S++             +R SS P       
Sbjct: 166 AGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSP 225

Query: 156 -------NFIPLFTPQSPVTATLSD--EDDGFVDLLDGENLKNEEETPSCMASLWTAPLV 206
                     PL   +  +T    D  EDDGFVD+L+ + LK+++  P  M SL +APLV
Sbjct: 226 DRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESD-LKDDDAVPPGMESLISAPLV 284

Query: 207 MRTTNLD-------NRC-KLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGAS 258
                 +       ++C +LF SPS+  S  R +LKR ER Q+   P   KRR+S++   
Sbjct: 285 KTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVT--P 342

Query: 259 PKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLK 318
           P+E    E+    + +S SL       IEN+LD+D R+LIGD+SK +L  TV GKHQDLK
Sbjct: 343 PEEQQEAEEPKARVLRSKSLCHDE---IENLLDSDHRELIGDYSKAFLLQTVDGKHQDLK 399

Query: 319 YISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIV 378
           YISPE M ++L GKF+N++ +FVI+DCRYPYEYEGGHIK AVNL +E + E FLLK PI 
Sbjct: 400 YISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIA 459

Query: 379 PTD-GKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKC 437
           P    KRVI++FHCEFSSERGPRMCR++RERDR  N+YP L+YPE+Y+LKGGYKEFF + 
Sbjct: 460 PCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQH 519

Query: 438 QSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLK 482
            ++CEP  YRPM+HE FK++LK FR K+R+WAGE+S+RE+ SRL+
Sbjct: 520 PNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQ 564


>gi|11641413 cell division cycle 25B isoform 1 [Homo sapiens]
          Length = 580

 Score =  374 bits (961), Expect = e-104
 Identities = 228/539 (42%), Positives = 306/539 (56%), Gaps = 98/539 (18%)

Query: 36  AGGLSPVTNLTVTMDQLQGLGSDYEQP----LEVKNNSNLQRMG-------------SSE 78
           A   SPVT LT TM  L GLGS+  +     L  ++ S L  +              SSE
Sbjct: 46  AAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSE 105

Query: 79  STDSGFCLDSPGPLDSK-----------------ENLENPMRRIHSLPQKLLGCSPALKR 121
           S+D+G C+DSP P+D                    N +  +RR  S+P +LLG SP L+ 
Sbjct: 106 SSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRN 165

Query: 122 ---------------------SHSDSLDHDIFQLIDPDENKENLSSN------------- 147
                                S  +  ++D F    P +     S++             
Sbjct: 166 ITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFA 225

Query: 148 ERDSSEPG-------------NFIPLFTPQSPVTATLSD--EDDGFVDLLDGENLKNEEE 192
           +R SS P                 PL   +  +T    D  EDDGFVD+L+ + LK+++ 
Sbjct: 226 QRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESD-LKDDDA 284

Query: 193 TPSCMASLWTAPLVMRTTNLD-------NRC-KLFDSPSLCSSSTRSVLKRPERSQEESP 244
            P  M SL +APLV      +       ++C +LF SPS+  S  R +LKR ER Q+   
Sbjct: 285 VPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDT 344

Query: 245 PGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKG 304
           P   KRR+S++   P+E    E+    + +S SL       IEN+LD+D R+LIGD+SK 
Sbjct: 345 PVQNKRRRSVT--PPEEQQEAEEPKARVLRSKSLCHDE---IENLLDSDHRELIGDYSKA 399

Query: 305 YLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHM 364
           +L  TV GKHQDLKYISPE M ++L GKF+N++ +FVI+DCRYPYEYEGGHIK AVNL +
Sbjct: 400 FLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPL 459

Query: 365 EEEVEDFLLKKPIVPTD-GKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPEL 423
           E + E FLLK PI P    KRVI++FHCEFSSERGPRMCR++RERDR  N+YP L+YPE+
Sbjct: 460 ERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEM 519

Query: 424 YVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLK 482
           Y+LKGGYKEFF +  ++CEP  YRPM+HE FK++LK FR K+R+WAGE+S+RE+ SRL+
Sbjct: 520 YILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQ 578


>gi|11641411 cell division cycle 25B isoform 3 [Homo sapiens]
          Length = 539

 Score =  373 bits (958), Expect = e-103
 Identities = 222/500 (44%), Positives = 296/500 (59%), Gaps = 61/500 (12%)

Query: 36  AGGLSPVTNLTVTMDQLQGLGSDYEQP----LEVKNNSNLQRMG-------------SSE 78
           A   SPVT LT TM  L GLGS+  +     L  ++ S L  +              SSE
Sbjct: 46  AAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSE 105

Query: 79  STDSGFCLDSPGPLDSK-----------------ENLENPMRRIHSLPQKLLGCSPALKR 121
           S+D+G C+DSP P+D                    N +  +RR  S+P   +   P  K 
Sbjct: 106 SSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPDGFVFKMP-WKP 164

Query: 122 SHSDSLDHDIFQLIDPDENKENLSSNERD--------SSEPGNFIPLFTPQSPVTATLSD 173
           +H  S  H + +     E      S+  D          E     PL   +  +T    D
Sbjct: 165 THPSST-HALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLTPAEGD 223

Query: 174 --EDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLD-------NRC-KLFDSPS 223
             EDDGFVD+L+ + LK+++  P  M SL +APLV      +       ++C +LF SPS
Sbjct: 224 TEEDDGFVDILESD-LKDDDAVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPS 282

Query: 224 LCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPK 283
           +  S  R +LKR ER Q+   P   KRR+S++   P+E    E+    + +S SL     
Sbjct: 283 MPCSVIRPILKRLERPQDRDTPVQNKRRRSVT--PPEEQQEAEEPKARVLRSKSLCHDE- 339

Query: 284 GTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVII 343
             IEN+LD+D R+LIGD+SK +L  TV GKHQDLKYISPE M ++L GKF+N++ +FVI+
Sbjct: 340 --IENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIV 397

Query: 344 DCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTD-GKRVIVVFHCEFSSERGPRMC 402
           DCRYPYEYEGGHIK AVNL +E + E FLLK PI P    KRVI++FHCEFSSERGPRMC
Sbjct: 398 DCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMC 457

Query: 403 RYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFR 462
           R++RERDR  N+YP L+YPE+Y+LKGGYKEFF +  ++CEP  YRPM+HE FK++LK FR
Sbjct: 458 RFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFR 517

Query: 463 TKSRTWAGEKSKREMYSRLK 482
            K+R+WAGE+S+RE+ SRL+
Sbjct: 518 LKTRSWAGERSRRELCSRLQ 537


>gi|125625350 cell division cycle 25C isoform a [Homo sapiens]
          Length = 473

 Score =  262 bits (669), Expect = 6e-70
 Identities = 172/437 (39%), Positives = 246/437 (56%), Gaps = 41/437 (9%)

Query: 56  GSDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGC 115
           G   ++ L++ N S+ +   +  +T +   LD  G LDS    E  +  ++   Q L+ C
Sbjct: 65  GGTPKRCLDLSNLSSGEITATQLTTSAD--LDETGHLDSSGLQEVHLAGMNH-DQHLMKC 121

Query: 116 SPA-LKRSHSDSLDHDIFQ---LIDPDENKENLSSNERDSSEPGNFIPLFT-PQSPVTAT 170
           SPA L  S  + LD    +   +     NKEN + N  DS       P+ T P+      
Sbjct: 122 SPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPN 181

Query: 171 LS-DEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSST 229
           L  D+ +   D L   +LK++E   S                   R  L+ SPS+  +  
Sbjct: 182 LGEDQAEEISDELMEFSLKDQEAKVS-------------------RSGLYRSPSMPENLN 222

Query: 230 RSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENI 289
           R  LK+ E+ ++ + P   K++        ++          L +++SL      TI  +
Sbjct: 223 RPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGL-------CLKKTVSLCDI---TITQM 272

Query: 290 LDNDPRD--LIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRY 347
           L+ D     LIGDFSK     TV+GKHQDLKY++PE +A++L+GKF  LI++F +IDCRY
Sbjct: 273 LEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKFYVIDCRY 332

Query: 348 PYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDG-KRVIVVFHCEFSSERGPRMCRYVR 406
           PYEY GGHI+GA+NL+ +EE+ +F LKKPIVP D  KR+I+VFHCEFSSERGPRMCR +R
Sbjct: 333 PYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGPRMCRCLR 392

Query: 407 ERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSR 466
           E DR  N+YP L+YPELY+LKGGY++FF +    CEP SY PMHH+D K +L + R++S+
Sbjct: 393 EEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELLRCRSQSK 452

Query: 467 TWAGEKSKREMYSRLKK 483
              GE+  RE  + L K
Sbjct: 453 VQEGERQLREQIALLVK 469


>gi|12408658 cell division cycle 25C isoform b [Homo sapiens]
          Length = 400

 Score =  255 bits (652), Expect = 5e-68
 Identities = 132/273 (48%), Positives = 183/273 (67%), Gaps = 13/273 (4%)

Query: 214 NRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLH 273
           +R  L+ SPS+  +  R  LK+ E+ ++ + P   K++        ++          L 
Sbjct: 134 SRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGL-------CLK 186

Query: 274 QSLSLASSPKGTIENILDNDPRD--LIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNG 331
           +++SL      TI  +L+ D     LIGDFSK     TV+GKHQDLKY++PE +A++L+G
Sbjct: 187 KTVSLCDI---TITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSG 243

Query: 332 KFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDG-KRVIVVFH 390
           KF  LI++F +IDCRYPYEY GGHI+GA+NL+ +EE+ +F LKKPIVP D  KR+I+VFH
Sbjct: 244 KFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFH 303

Query: 391 CEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMH 450
           CEFSSERGPRMCR +RE DR  N+YP L+YPELY+LKGGY++FF +    CEP SY PMH
Sbjct: 304 CEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMH 363

Query: 451 HEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKK 483
           H+D K +L + R++S+   GE+  RE  + L K
Sbjct: 364 HQDHKTELLRCRSQSKVQEGERQLREQIALLVK 396


>gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo
           sapiens]
          Length = 621

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 47/199 (23%), Positives = 82/199 (41%), Gaps = 16/199 (8%)

Query: 142 ENLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLW 201
           E+L   ER S   G        + P     SDED    +L+  E+  +E  +P+      
Sbjct: 76  ESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVDEDQPSEPPSPA------ 129

Query: 202 TAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKE 261
           T P       +  R  L DSP+  +SS  S L R +       P ST   KS   + P++
Sbjct: 130 TTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTPASKSCDSSPPQD 189

Query: 262 STNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLK--- 318
           ++ P     +      LA+ P  + +++    P  L   F+  +   + +  + DL    
Sbjct: 190 ASTP--GPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHSTLNGDLSVPS 247

Query: 319 -----YISPEIMASVLNGK 332
                ++SP++ +SV+ G+
Sbjct: 248 SYVSLHLSPQVSSSVVYGR 266


>gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo
           sapiens]
          Length = 706

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 47/199 (23%), Positives = 82/199 (41%), Gaps = 16/199 (8%)

Query: 142 ENLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLW 201
           E+L   ER S   G        + P     SDED    +L+  E+  +E  +P+      
Sbjct: 212 ESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVDEDQPSEPPSPA------ 265

Query: 202 TAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKE 261
           T P       +  R  L DSP+  +SS  S L R +       P ST   KS   + P++
Sbjct: 266 TTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTPASKSCDSSPPQD 325

Query: 262 STNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLK--- 318
           ++ P     +      LA+ P  + +++    P  L   F+  +   + +  + DL    
Sbjct: 326 ASTP--GPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHSTLNGDLSVPS 383

Query: 319 -----YISPEIMASVLNGK 332
                ++SP++ +SV+ G+
Sbjct: 384 SYVSLHLSPQVSSSVVYGR 402


>gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo
           sapiens]
          Length = 743

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 47/199 (23%), Positives = 82/199 (41%), Gaps = 16/199 (8%)

Query: 142 ENLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLW 201
           E+L   ER S   G        + P     SDED    +L+  E+  +E  +P+      
Sbjct: 198 ESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVDEDQPSEPPSPA------ 251

Query: 202 TAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKE 261
           T P       +  R  L DSP+  +SS  S L R +       P ST   KS   + P++
Sbjct: 252 TTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTPASKSCDSSPPQD 311

Query: 262 STNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLK--- 318
           ++ P     +      LA+ P  + +++    P  L   F+  +   + +  + DL    
Sbjct: 312 ASTP--GPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHSTLNGDLSVPS 369

Query: 319 -----YISPEIMASVLNGK 332
                ++SP++ +SV+ G+
Sbjct: 370 SYVSLHLSPQVSSSVVYGR 388


>gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]
          Length = 1503

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 50/183 (27%), Positives = 76/183 (41%), Gaps = 37/183 (20%)

Query: 55  LGSDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLG 114
           +GSDY   LE K+ SNL+             LD P  L + + ++NP R    L Q    
Sbjct: 547 VGSDYYIQLEEKSGSNLE-------------LDYPPALLTTD-MDNPERTGPELSQLTAL 592

Query: 115 CSPALKRSHSDSLDHDIFQLIDPDENKENLSSNERDSSEPGNFIPLFTPQSPVTATLSDE 174
            S  L+ S   S D D FQ           S++ +DSS PG+      P+SP     +D 
Sbjct: 593 RSVELEES---STDEDFFQS----------STDPKDSSLPGDLHVTSGPESPFNNIFNDV 639

Query: 175 DDG--------FVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNR--CKLFDSPSL 224
           D            DL++   ++ + +  +  +SL      + T + +     K+FDS  L
Sbjct: 640 DKSEDLPSHQKIFDLMELNGVQADFKPATLSSSLDNPKESVITGHFEKEKPRKIFDSEPL 699

Query: 225 CSS 227
           C S
Sbjct: 700 CLS 702


>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
          Length = 238

 Score = 37.0 bits (84), Expect = 0.040
 Identities = 22/51 (43%), Positives = 31/51 (60%), Gaps = 2/51 (3%)

Query: 217 KLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEK 267
           + F SPS   S +RS+  RP  S+ +S   S KR +S SG SP+ S +PE+
Sbjct: 188 RYFQSPSRSRSRSRSI-SRPRSSRSKSRSPSPKRSRSPSG-SPRRSASPER 236


>gi|40538736 RAN binding protein 10 [Homo sapiens]
          Length = 620

 Score = 36.2 bits (82), Expect = 0.068
 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 8/104 (7%)

Query: 220 DSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASP-----KESTNPEKAHETLHQ 274
           DSPS CS+   S   +   S+  +P  S+    S S +SP      ES + +      H 
Sbjct: 385 DSPS-CSNGVASTKSKQNHSKYPAPSSSSSSSSSSSSSSPSSVNYSESNSTDSTKSQHHS 443

Query: 275 SLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLK 318
           S S   +    +E   ++ P  ++G  S   +    A KH+DL+
Sbjct: 444 STSNQETSDSEMEMEAEHYPNGVLGSMSTRIV--NGAYKHEDLQ 485


>gi|9257222 forkhead box O1 [Homo sapiens]
          Length = 655

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 56/230 (24%), Positives = 86/230 (37%), Gaps = 32/230 (13%)

Query: 66  KNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHSD 125
           K+  + +R  +S   +S F          K +L++        P       PA   SHS+
Sbjct: 245 KSGKSPRRRAASMDNNSKFAKSRSRAAKKKASLQSGQEGAGDSPGSQFSKWPASPGSHSN 304

Query: 126 SLDHDIFQLIDPDENKENLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGE 185
             D D +    P       SSN   S+  G   P+ T Q               DL +G+
Sbjct: 305 D-DFDNWSTFRP-----RTSSNA--STISGRLSPIMTEQD--------------DLGEGD 342

Query: 186 NLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPP 245
            + +    PS      T P +   +N +N   L D+ +L SS T   +     S + SP 
Sbjct: 343 -VHSMVYPPSAAKMASTLPSLSEISNPENMENLLDNLNLLSSPTSLTV-----STQSSPG 396

Query: 246 GSTKRRKSMSGASPKESTN---PEKAHETLHQSLSLASSPKGTIENILDN 292
              ++    S A P  S N   P     T  QS S++  P+  I+ + DN
Sbjct: 397 TMMQQTPCYSFAPPNTSLNSPSPNYQKYTYGQS-SMSPLPQMPIQTLQDN 445


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 34.3 bits (77), Expect = 0.26
 Identities = 58/227 (25%), Positives = 83/227 (36%), Gaps = 44/227 (19%)

Query: 77  SESTDSGFC---LDSPGPLDSKENLENPMRRIHSLPQKLLGCSPAL----KRSHSDSLDH 129
           ++ST  GF    L  P      EN  +P++ + SLP+     SP           DSL  
Sbjct: 502 TQSTFEGFPQSPLQIPQSPPEGENTHSPLQIVPSLPEWEDSLSPHYFPQSPPQGEDSLSP 561

Query: 130 DIFQLIDPDENKENLSSNERDSSEPG--NFIPLFTPQSPVTATLSDEDDGFVDLLDGENL 187
             F    P + +++LS +    S  G  +  P + PQSP        +D    L   ++ 
Sbjct: 562 HYFPQ-SPPQGEDSLSPHYFPQSPQGEDSLSPHYFPQSPPQG-----EDSMSPLYFPQSP 615

Query: 188 KNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGS 247
              EE  S + S                       S+CSSST S L +      +SPP  
Sbjct: 616 LQGEEFQSSLQS---------------------PVSICSSSTPSSLPQSFPESSQSPPEG 654

Query: 248 TKRRKSMSGASPKES-------TNPEKAHETLHQSLSLASSPKGTIE 287
             +    S  SP E         +PE A E    SLS    P+  +E
Sbjct: 655 PVQSPLHSPQSPPEGMHSQSPLQSPESAPEG-EDSLSPLQIPQSPLE 700


>gi|162287219 prune homolog 2 [Homo sapiens]
          Length = 3088

 Score = 32.7 bits (73), Expect = 0.76
 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 10/98 (10%)

Query: 145  SSNERDSSEPGNFIPLFTPQSPVTATLS-----DEDDGFVDLLDGENLKNEEETPSCMAS 199
            SS  R SS PGN     +P +  ++ ++     DE++   +  DG+N+  E++      S
Sbjct: 1018 SSRNRISSGPGNLDMWASPHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESSQS 1077

Query: 200  LWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPE 237
             +  P +M+  N  NR       +L  SST S    P+
Sbjct: 1078 SYDDPSMMQLYNETNR-----QLTLLHSSTNSRQTAPD 1110


>gi|169179759 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score = 32.3 bits (72), Expect = 0.99
 Identities = 17/42 (40%), Positives = 22/42 (52%)

Query: 4   GPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNL 45
           GP    R ++L AC+P P  Q    A+ G  AAG   PV+ L
Sbjct: 215 GPPGQEREQVLRACAPQPQHQVDCSAVGGPMAAGEKPPVSRL 256


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 32.3 bits (72), Expect = 0.99
 Identities = 49/227 (21%), Positives = 86/227 (37%), Gaps = 21/227 (9%)

Query: 67  NNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHSDS 126
           N+ +    G S+S+DS    DS    DS ++ ++               S +   S SDS
Sbjct: 537 NDKSDSGKGKSDSSDSDSS-DSSNSSDSSDSSDSDS-------------SDSNSSSDSDS 582

Query: 127 LDHDIFQLIDPDENKENLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGEN 186
            D D     D D +  + SS+  DSS+  +     +  S  + + SD      D  D ++
Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSDSSDSSD----SSDSSDSSDSKSDSSKSESDSSDSDS 638

Query: 187 LKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPG 246
             +  ++ S  +S         ++N  N     DS     SS+ S       S + S   
Sbjct: 639 KSDSSDSNSSDSS--DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696

Query: 247 STKRRKSMSGASPKEST-NPEKAHETLHQSLSLASSPKGTIENILDN 292
           ++      S +S  +S+ + + ++     S S  SS      N  D+
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS 743



 Score = 30.0 bits (66), Expect = 4.9
 Identities = 46/236 (19%), Positives = 85/236 (36%), Gaps = 6/236 (2%)

Query: 57   SDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCS 116
            SD     +  N+S+     SS+S+DS    DS    DS ++ ++      S        S
Sbjct: 954  SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013

Query: 117  PALKRSHSDSLDHDIFQLIDPDENKENLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDD 176
             +   S S +           D +  + SS+  DSS+  +     +  S  ++  SD  D
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD-----SSNSSDSSDSSDSSD 1068

Query: 177  GFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRP 236
               D  D  +  +  E+     S  ++     + + D+      S S  SS + +     
Sbjct: 1069 S-SDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127

Query: 237  ERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDN 292
            + S       S+    S   +   +S++   + ++   S S  SS      N  D+
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 48/229 (20%), Positives = 82/229 (35%), Gaps = 15/229 (6%)

Query: 67  NNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHS-- 124
           N+S+     SS+S+DS    DS    DS  + ++      S        S +   S S  
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781

Query: 125 DSLDHDIFQLID-PDENKENLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLD 183
            S  +D     D  D +  + SSN  DSS+  +     +  S  ++  SD  D       
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841

Query: 184 GENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEES 243
            ++  + + + S             ++N  +     DS     SS  S       S E S
Sbjct: 842 SDSSDSSDGSDS------------DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889

Query: 244 PPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDN 292
               +    + S +   +S+N   + ++ + S S  SS      N  D+
Sbjct: 890 NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938


>gi|21361348 UTP14, U3 small nucleolar ribonucleoprotein, homolog A
           [Homo sapiens]
          Length = 771

 Score = 32.3 bits (72), Expect = 0.99
 Identities = 21/65 (32%), Positives = 31/65 (47%)

Query: 230 RSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENI 289
           RS+ KR E SQ+  P GS + + S S     E     +  +  HQS    +S +GTI  +
Sbjct: 428 RSLRKRSELSQDAEPAGSQETKDSGSQEVLSELRVLSQKLKENHQSRKQKASSEGTIPQV 487

Query: 290 LDNDP 294
              +P
Sbjct: 488 QREEP 492


>gi|169180158 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 17/42 (40%), Positives = 22/42 (52%)

Query: 4   GPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNL 45
           GP    R ++L AC+P P  Q    A+ G  AAG   PV+ L
Sbjct: 215 GPPGQEREQVLRACAPQPQHQVDCSAVGGPVAAGEKPPVSRL 256


>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
            sapiens]
          Length = 2715

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 11/115 (9%)

Query: 81   DSGFC-LDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDE 139
            +SGF  + S    DSK NL +  + I  L  K L     L ++HSD          + +E
Sbjct: 1820 ESGFVDMCSLSVCDSKRNLSSDQQLIDLLENKSLESKLILSQNHSD----------EEEE 1869

Query: 140  NKENLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETP 194
             +EN   N   +   G    +     P T    +++ GF D     +L+   +TP
Sbjct: 1870 EEENEEENLAMAVGMGERPEVLHLTEPTTNISREKNQGFQDETKKGSLEVANQTP 1924


>gi|33356547 minichromosome maintenance complex component 2 [Homo
           sapiens]
          Length = 904

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 14/87 (16%)

Query: 92  LDSKENLENPMRRIHSLPQKLLGCSPALK---------RSHSDSLDHDIFQLIDPD---E 139
           ++S ENLE+   + HS+ + +    P L+         R+H DS  H++F+    D   E
Sbjct: 168 IESIENLED--LKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKE 225

Query: 140 NKENLSSNERDSSEPGNFIPLFTPQSP 166
           N+E+L  N  D +   + +  F P++P
Sbjct: 226 NRESLVVNYEDLAAREHVLAYFLPEAP 252


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
            sapiens]
          Length = 4911

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 6/88 (6%)

Query: 92   LDSKENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDENKENLSSNERDS 151
            +++ + LE          Q+  G    L +S SD+    I   + P     N+S  +   
Sbjct: 1767 IEATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFH 1826

Query: 152  SEPGNFIPLFTPQSPVTATLSDEDDGFV 179
             E      LFT Q P T T +  DD FV
Sbjct: 1827 KE------LFTKQPPSTPTSTSSDDVFV 1848


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 40/194 (20%), Positives = 72/194 (37%), Gaps = 10/194 (5%)

Query: 87  DSPGPLDSKENLENPMRRIHSLPQKLLGCSP---ALKRSHSDSLDHDIFQLIDPDENKEN 143
           DS    + +E ++ P  +  ++P K +G  P   A K S S S +       + D+ K+ 
Sbjct: 86  DSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQP 145

Query: 144 LSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLWTA 203
           +    +  ++     P     S   +  S ED+        +N K +    +  A     
Sbjct: 146 VQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDE------PPKNQKPKITPVTVKAQTKAP 199

Query: 204 PLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKEST 263
           P   R        K   S S  SSS+ S     E     +P  +  +++ ++ A  K +T
Sbjct: 200 PKPARAAPKIANGKAASSSS-SSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAAT 258

Query: 264 NPEKAHETLHQSLS 277
            P +   +   S S
Sbjct: 259 TPTRKSSSSEDSSS 272


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 13/28 (46%), Positives = 20/28 (71%)

Query: 341 VIIDCRYPYEYEGGHIKGAVNLHMEEEV 368
           VIIDCR   EY   HI+GAV+++  +++
Sbjct: 173 VIIDCRPFMEYNKSHIQGAVHINCADKI 200


>gi|22748641 CHMP family, member 7 [Homo sapiens]
          Length = 453

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 7/75 (9%)

Query: 217 KLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSL 276
           +L  S  L S    S+ +  ER +EE+       +K ++  S K     EK  E LH  L
Sbjct: 243 QLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKL 302

Query: 277 SLASSPKGTIENILD 291
                   T++ ILD
Sbjct: 303 D-------TVQGILD 310


>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
          Length = 752

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 61/286 (21%), Positives = 102/286 (35%), Gaps = 54/286 (18%)

Query: 51  QLQGLGSDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQ 110
           Q+  LG+D  +   ++ +   + + S E T          P+  K+   +  +R   L  
Sbjct: 130 QVNVLGTDVVRQSILRRSPGAEEVQSQEQTRQDAEKSDTSPVAGKKASHDGPKRKGFLLS 189

Query: 111 KLLGCSPA--------LKRSHSDSLDHDIFQLID--PDENKENLSSNERDSSEPG----- 155
           K    +            RS+S  LD   F+ +   P  ++ +  S++ +  EPG     
Sbjct: 190 KFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQEPGPRTPK 249

Query: 156 ----NFIPLFTPQSPVTATLS-----DEDDGFVDLLDGENLK--NEEETPSCMASLWTAP 204
               N +   T  SP  +T +       + GF + +D   ++  ++E T S   +    P
Sbjct: 250 SSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSHRRNTSGTP 309

Query: 205 LVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKE--- 261
            +                SL S  +RS L   E   E+S    + R KS+ GA  K+   
Sbjct: 310 SIA-----------VSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLE 358

Query: 262 --------------STNPEKAHETLHQSLSLASSPKGTIENILDND 293
                         STN  +    L  S    S  K T  N+ D D
Sbjct: 359 ETEESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDAD 404


>gi|169183882 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 16/42 (38%), Positives = 21/42 (50%)

Query: 4   GPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNL 45
           GP    R ++L AC+P P  Q     + G  AAG   PV+ L
Sbjct: 215 GPPGQEREQVLRACAPQPQHQVDCSTVGGPMAAGEKPPVSRL 256


>gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapiens]
          Length = 1955

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 39/161 (24%), Positives = 68/161 (42%), Gaps = 20/161 (12%)

Query: 95   KENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDENKEN--LSSNERDSS 152
            +E ++    +  SLP++L+   P    +  + +D   +Q        EN  + +N+R SS
Sbjct: 1567 REKIQRLWSQSVSLPRRLMRKVP----NRPEIIDLQQWQGTRQKAENENTGICTNKRGSS 1622

Query: 153  EPGNFIPLFTPQSPVTATLSDEDDGFVDLLDG-ENLKN-EEETPSCMA----SLWTAPLV 206
             P     L T +        +   G   +++G E LK+   ++  C      S  T P V
Sbjct: 1623 NP-----LLTTEEANLTEKEEIRQGETLMIEGTEQLKSLSSDSSFCFPRPHFSFSTLPTV 1677

Query: 207  MRTTNLDNRCKLFDSPSLCS---SSTRSVLKRPERSQEESP 244
             RT  L +   +  SP+ CS   S +R  +     S+ E+P
Sbjct: 1678 SRTVELKSEPNVISSPAECSLELSPSRPCVLHSSLSRRETP 1718


>gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sapiens]
          Length = 1932

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 39/161 (24%), Positives = 68/161 (42%), Gaps = 20/161 (12%)

Query: 95   KENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDENKEN--LSSNERDSS 152
            +E ++    +  SLP++L+   P    +  + +D   +Q        EN  + +N+R SS
Sbjct: 1544 REKIQRLWSQSVSLPRRLMRKVP----NRPEIIDLQQWQGTRQKAENENTGICTNKRGSS 1599

Query: 153  EPGNFIPLFTPQSPVTATLSDEDDGFVDLLDG-ENLKN-EEETPSCMA----SLWTAPLV 206
             P     L T +        +   G   +++G E LK+   ++  C      S  T P V
Sbjct: 1600 NP-----LLTTEEANLTEKEEIRQGETLMIEGTEQLKSLSSDSSFCFPRPHFSFSTLPTV 1654

Query: 207  MRTTNLDNRCKLFDSPSLCS---SSTRSVLKRPERSQEESP 244
             RT  L +   +  SP+ CS   S +R  +     S+ E+P
Sbjct: 1655 SRTVELKSEPNVISSPAECSLELSPSRPCVLHSSLSRRETP 1695


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.133    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,026,579
Number of Sequences: 37866
Number of extensions: 1123803
Number of successful extensions: 3401
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 3334
Number of HSP's gapped (non-prelim): 87
length of query: 484
length of database: 18,247,518
effective HSP length: 106
effective length of query: 378
effective length of database: 14,233,722
effective search space: 5380346916
effective search space used: 5380346916
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.