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Search of human proteins with 42415492
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens]
(1132 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens] 2264 0.0
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 49 3e-05
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 49 3e-05
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 49 4e-05
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 49 4e-05
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 48 5e-05
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 46 2e-04
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 44 9e-04
gi|71061468 centromere protein E [Homo sapiens] 43 0.001
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 42 0.003
gi|47578107 delangin isoform B [Homo sapiens] 42 0.003
gi|47578105 delangin isoform A [Homo sapiens] 42 0.003
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 41 0.006
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 40 0.010
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 40 0.010
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 40 0.010
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 40 0.010
gi|45439370 TAO kinase 1 [Homo sapiens] 40 0.016
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 40 0.016
gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ... 40 0.016
gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform... 40 0.016
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 39 0.021
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 39 0.021
gi|87299628 biorientation of chromosomes in cell division 1-like... 39 0.021
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 39 0.028
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 39 0.028
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 39 0.036
gi|224586823 coiled-coil domain containing 110 isoform b [Homo s... 38 0.048
gi|22749515 coiled-coil domain containing 110 isoform a [Homo sa... 38 0.048
gi|150010604 kinesin family member 4B [Homo sapiens] 37 0.081
>gi|42415492 chromosome 14 open reading frame 106 [Homo sapiens]
Length = 1132
Score = 2264 bits (5868), Expect = 0.0
Identities = 1132/1132 (100%), Positives = 1132/1132 (100%)
Query: 1 MIATPLKHSRIYLPPEASSQRRNLPMDAIFFDSIPSGTLTPVKDLVKYQNSSLKLNDHKK 60
MIATPLKHSRIYLPPEASSQRRNLPMDAIFFDSIPSGTLTPVKDLVKYQNSSLKLNDHKK
Sbjct: 1 MIATPLKHSRIYLPPEASSQRRNLPMDAIFFDSIPSGTLTPVKDLVKYQNSSLKLNDHKK 60
Query: 61 NQFLKMTTFNNKNIFQSTMLTEATTSNSSLDISAIKPNKDGLKNKANYESPGKIFLRMKE 120
NQFLKMTTFNNKNIFQSTMLTEATTSNSSLDISAIKPNKDGLKNKANYESPGKIFLRMKE
Sbjct: 61 NQFLKMTTFNNKNIFQSTMLTEATTSNSSLDISAIKPNKDGLKNKANYESPGKIFLRMKE 120
Query: 121 KVLRDKQEQPSRNSSLLEPQKSGNNETFTPNRVEKKKLQHTYLCEEKENNKSFQSDDSSL 180
KVLRDKQEQPSRNSSLLEPQKSGNNETFTPNRVEKKKLQHTYLCEEKENNKSFQSDDSSL
Sbjct: 121 KVLRDKQEQPSRNSSLLEPQKSGNNETFTPNRVEKKKLQHTYLCEEKENNKSFQSDDSSL 180
Query: 181 RASVQGVPLESSNNDIFLPVKQKIQCQQEKKAPLHNLTYELPTLNQEQENFLAVEARNKT 240
RASVQGVPLESSNNDIFLPVKQKIQCQQEKKAPLHNLTYELPTLNQEQENFLAVEARNKT
Sbjct: 181 RASVQGVPLESSNNDIFLPVKQKIQCQQEKKAPLHNLTYELPTLNQEQENFLAVEARNKT 240
Query: 241 LTRAQLAKQIFHSKESIVATTKSKKDTFVLESVDSADEQFQNTNAETLSTNCIPIKNGSL 300
LTRAQLAKQIFHSKESIVATTKSKKDTFVLESVDSADEQFQNTNAETLSTNCIPIKNGSL
Sbjct: 241 LTRAQLAKQIFHSKESIVATTKSKKDTFVLESVDSADEQFQNTNAETLSTNCIPIKNGSL 300
Query: 301 LMVSDSERTTEGTSQQKVKEGNGKTVPGETGLPGSMKDTCKIVLATPRLHITIPRRSKRN 360
LMVSDSERTTEGTSQQKVKEGNGKTVPGETGLPGSMKDTCKIVLATPRLHITIPRRSKRN
Sbjct: 301 LMVSDSERTTEGTSQQKVKEGNGKTVPGETGLPGSMKDTCKIVLATPRLHITIPRRSKRN 360
Query: 361 ISKLSPPRIFQTVTNGLKKNQVVQLQEWMIKSINNNTAICVEGKLIDVTNIYWHSNVIIE 420
ISKLSPPRIFQTVTNGLKKNQVVQLQEWMIKSINNNTAICVEGKLIDVTNIYWHSNVIIE
Sbjct: 361 ISKLSPPRIFQTVTNGLKKNQVVQLQEWMIKSINNNTAICVEGKLIDVTNIYWHSNVIIE 420
Query: 421 RIEHNKLRTISGNVYILKGMIDQISMKEAGYPNYLIRKFMFGFPENWKEHIDNFLEQLRA 480
RIEHNKLRTISGNVYILKGMIDQISMKEAGYPNYLIRKFMFGFPENWKEHIDNFLEQLRA
Sbjct: 421 RIEHNKLRTISGNVYILKGMIDQISMKEAGYPNYLIRKFMFGFPENWKEHIDNFLEQLRA 480
Query: 481 GEKNREKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTYDFDCDNLELKSNKHSE 540
GEKNREKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTYDFDCDNLELKSNKHSE
Sbjct: 481 GEKNREKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTYDFDCDNLELKSNKHSE 540
Query: 541 SPGATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKKLKIG 600
SPGATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKKLKIG
Sbjct: 541 SPGATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKKLKIG 600
Query: 601 ERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAINQKKAYILVTPLKSRKV 660
ERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAINQKKAYILVTPLKSRKV
Sbjct: 601 ERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAINQKKAYILVTPLKSRKV 660
Query: 661 IEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDERDLL 720
IEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDERDLL
Sbjct: 661 IEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDERDLL 720
Query: 721 TVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYKHQSSPDLSSEESETEK 780
TVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYKHQSSPDLSSEESETEK
Sbjct: 721 TVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYKHQSSPDLSSEESETEK 780
Query: 781 EIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVK 840
EIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVK
Sbjct: 781 EIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVK 840
Query: 841 ETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGLIQDKEWNEKELQKLHCAFASLPKHKP 900
ETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGLIQDKEWNEKELQKLHCAFASLPKHKP
Sbjct: 841 ETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGLIQDKEWNEKELQKLHCAFASLPKHKP 900
Query: 901 GFWSEVAAAVGSRSPEECQRKYMENPRGKGSQKHVTKKKPANSKGQNGKRGDADQKQTIK 960
GFWSEVAAAVGSRSPEECQRKYMENPRGKGSQKHVTKKKPANSKGQNGKRGDADQKQTIK
Sbjct: 901 GFWSEVAAAVGSRSPEECQRKYMENPRGKGSQKHVTKKKPANSKGQNGKRGDADQKQTIK 960
Query: 961 ITAKVGTLKRKQQMREFLEQLPKDDHDDFFSTTPLQHQRILLPSFQDSEDDDDILPNMDK 1020
ITAKVGTLKRKQQMREFLEQLPKDDHDDFFSTTPLQHQRILLPSFQDSEDDDDILPNMDK
Sbjct: 961 ITAKVGTLKRKQQMREFLEQLPKDDHDDFFSTTPLQHQRILLPSFQDSEDDDDILPNMDK 1020
Query: 1021 NPTTPSSVIFPLVKTPQCQHVSPGMLGSINRNDCDKYVFRMQKYHKSNGGIVWGNIKKKL 1080
NPTTPSSVIFPLVKTPQCQHVSPGMLGSINRNDCDKYVFRMQKYHKSNGGIVWGNIKKKL
Sbjct: 1021 NPTTPSSVIFPLVKTPQCQHVSPGMLGSINRNDCDKYVFRMQKYHKSNGGIVWGNIKKKL 1080
Query: 1081 VETDFSTPTPRRKTPFNTDLGENSGIGKLFTNAVESLDEEEKDYYFSNSDSA 1132
VETDFSTPTPRRKTPFNTDLGENSGIGKLFTNAVESLDEEEKDYYFSNSDSA
Sbjct: 1081 VETDFSTPTPRRKTPFNTDLGENSGIGKLFTNAVESLDEEEKDYYFSNSDSA 1132
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 48.9 bits (115), Expect = 3e-05
Identities = 39/203 (19%), Positives = 98/203 (48%), Gaps = 18/203 (8%)
Query: 442 DQISMKEAGYPNYLIRKFMFGFPENWKEHIDNFLEQLRAG-----EKNREKTKQKQKTGR 496
+Q+ K+ G + + +F ENWK+ ++ E+L +G +K + K K+K+K+GR
Sbjct: 36 EQLEKKKKG--SKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGR 93
Query: 497 SVRDIRKSMKNDARENQTDTAQRATTTYDFDCDNLELKSNKHSESPGATELNMCHSNCQN 556
+ + + +D++ ++ + D D + + K + S ++E +M + +
Sbjct: 94 ---------YSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDS 144
Query: 557 KPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKKLKIGERTNERIIKSQKQETT 616
K +L+ + T + LS + + ++ +SS+ L E E ++++K++++
Sbjct: 145 KDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEE--VRAKKKKSS 202
Query: 617 EELDVSIDILTSREQFFSDEERK 639
EE + + + +++ ++K
Sbjct: 203 EEREKATEKTKKKKKHKKHSKKK 225
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 48.9 bits (115), Expect = 3e-05
Identities = 39/203 (19%), Positives = 98/203 (48%), Gaps = 18/203 (8%)
Query: 442 DQISMKEAGYPNYLIRKFMFGFPENWKEHIDNFLEQLRAG-----EKNREKTKQKQKTGR 496
+Q+ K+ G + + +F ENWK+ ++ E+L +G +K + K K+K+K+GR
Sbjct: 46 EQLEKKKKG--SKALAEFEEKMNENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGR 103
Query: 497 SVRDIRKSMKNDARENQTDTAQRATTTYDFDCDNLELKSNKHSESPGATELNMCHSNCQN 556
+ + + +D++ ++ + D D + + K + S ++E +M + +
Sbjct: 104 ---------YSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDS 154
Query: 557 KPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKKLKIGERTNERIIKSQKQETT 616
K +L+ + T + LS + + ++ +SS+ L E E ++++K++++
Sbjct: 155 KDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEE--VRAKKKKSS 212
Query: 617 EELDVSIDILTSREQFFSDEERK 639
EE + + + +++ ++K
Sbjct: 213 EEREKATEKTKKKKKHKKHSKKK 235
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 48.5 bits (114), Expect = 4e-05
Identities = 95/473 (20%), Positives = 170/473 (35%), Gaps = 121/473 (25%)
Query: 513 QTDTAQRATTTYDFDCDNLELKSNKHSESPGATELNMCHSNCQNKPTLRFPDDQVNNTIQ 572
Q D + T +F ++ +KS KH E + H K + D+ + T +
Sbjct: 554 QPDLVRYDNTESEFLPESSSVKSCKHKEK--SKHQKDFHLEFGEKSNAKIKDEDHSPTFE 611
Query: 573 NGG---------GDDLSNQELIGKKEYKMSSKKLKIGERTNERIIKSQKQETTEELDVSI 623
N G L +L K+ K KK GE+ K + +++ +EL S+
Sbjct: 612 NSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKE-----KYKTKDSAKELQRSV 666
Query: 624 DILTS--REQFFSDEERKYMAINQKKAYILVTPLKSRKVIEQRCMRYNLSAGTIKAVTDF 681
+ +E FF +E + + +N + + +
Sbjct: 667 EFDREFWKENFFKSDETEDLFLNMEHESLTL----------------------------- 697
Query: 682 VIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDERDLLTVNRKIKISNLEKEQMLTSDF 741
+KKS + K++ ++T E H SK + +ERD + +K + +E++ D
Sbjct: 698 -----EKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKI---KKESEKSFREEKI--KDL 747
Query: 742 KKNTRLLPKLKKIE-NQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAV 800
K+ +P K E + MS + L +E + EK+ K
Sbjct: 748 KEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEK----------------- 790
Query: 801 VHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVKETLQKSGVRKEFPITEAVGS 860
H+++S I E + E+ E + + K+KK + K S
Sbjct: 791 -HIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHK-------------------S 830
Query: 861 DKTNRHPLECLPGLIQDKEWNEKELQKLHCAFASLPKHKPGFWSEVAAAVGSRSPEECQR 920
+K EC+ + KE KL+ + + HK G S+ AA+ E R
Sbjct: 831 EKDKLDLSECVDKI--------KEKDKLY-SHHTEKCHKEGEKSKNTAAIKKTDDREKSR 881
Query: 921 KYMENPRGK-----------GSQKHVTKKKPAN------SKGQNGKRGDADQK 956
+ M+ K +KH+ +KK SK + GK + D++
Sbjct: 882 EKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRE 934
Score = 37.0 bits (84), Expect = 0.11
Identities = 70/330 (21%), Positives = 126/330 (38%), Gaps = 57/330 (17%)
Query: 43 KDLVKYQNSSLKLNDHKKNQFLKMTTFNNKNIFQSTMLTEATTSNSSLDISAIKPNKDGL 102
K L++ +N +++ K++ K NK + E + S++I+ K ++
Sbjct: 905 KHLMEKKNKQSDNSEYSKSEKGK-----NKEKDRELDKKEKSRDKESINITNSKHIQEEK 959
Query: 103 K------NKANYESPGKIFLRMKEKVLRDKQEQPSRNSSLLEPQKSGNNETFTPNRVEKK 156
K NKA +E P L +KEK + + P + +K + + + K
Sbjct: 960 KSSIVDGNKAQHEKP----LSLKEKTKDEPLKTPDGKE---KDKKDKDIDRYKERDKHKD 1012
Query: 157 KLQHTYLCEEKENNKSFQSDDSSLRASVQGVPLESSNNDIF------------LPVKQ-- 202
K+Q L + K + S + N+D+ L ++Q
Sbjct: 1013 KIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWH 1072
Query: 203 ---KIQCQQEKKAPLHNLT-YELPTLNQEQENFLAVEARNKTLTRAQLAKQIFHSKESIV 258
K + +Q++K L N EL ++E+ E++NK LTR++ S E
Sbjct: 1073 KKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSK-------SSEVTD 1125
Query: 259 ATTKSKKDTFVLESVDSADEQFQNTNAETLSTNCIPIKNGSLLMVSDSERTTEGTSQQKV 318
A TK K+ ++V + + N TL + + + SL SE G S + V
Sbjct: 1126 AYTKEKQPK---DAVSNRSQSVDTKNVMTLGKSSF-VSDNSLNRSPRSENEKPGLSSRSV 1181
Query: 319 KEGNGKTVPGETGLPGSMKDTCKIVLATPR 348
+ S +D+C + TPR
Sbjct: 1182 SMIS----------VASSEDSCHTTVTTPR 1201
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 48.5 bits (114), Expect = 4e-05
Identities = 95/473 (20%), Positives = 170/473 (35%), Gaps = 121/473 (25%)
Query: 513 QTDTAQRATTTYDFDCDNLELKSNKHSESPGATELNMCHSNCQNKPTLRFPDDQVNNTIQ 572
Q D + T +F ++ +KS KH E + H K + D+ + T +
Sbjct: 577 QPDLVRYDNTESEFLPESSSVKSCKHKEK--SKHQKDFHLEFGEKSNAKIKDEDHSPTFE 634
Query: 573 NGG---------GDDLSNQELIGKKEYKMSSKKLKIGERTNERIIKSQKQETTEELDVSI 623
N G L +L K+ K KK GE+ K + +++ +EL S+
Sbjct: 635 NSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKE-----KYKTKDSAKELQRSV 689
Query: 624 DILTS--REQFFSDEERKYMAINQKKAYILVTPLKSRKVIEQRCMRYNLSAGTIKAVTDF 681
+ +E FF +E + + +N + + +
Sbjct: 690 EFDREFWKENFFKSDETEDLFLNMEHESLTL----------------------------- 720
Query: 682 VIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDERDLLTVNRKIKISNLEKEQMLTSDF 741
+KKS + K++ ++T E H SK + +ERD + +K + +E++ D
Sbjct: 721 -----EKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKI---KKESEKSFREEKI--KDL 770
Query: 742 KKNTRLLPKLKKIE-NQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAV 800
K+ +P K E + MS + L +E + EK+ K
Sbjct: 771 KEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEK----------------- 813
Query: 801 VHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVKETLQKSGVRKEFPITEAVGS 860
H+++S I E + E+ E + + K+KK + K S
Sbjct: 814 -HIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHK-------------------S 853
Query: 861 DKTNRHPLECLPGLIQDKEWNEKELQKLHCAFASLPKHKPGFWSEVAAAVGSRSPEECQR 920
+K EC+ + KE KL+ + + HK G S+ AA+ E R
Sbjct: 854 EKDKLDLSECVDKI--------KEKDKLY-SHHTEKCHKEGEKSKNTAAIKKTDDREKSR 904
Query: 921 KYMENPRGK-----------GSQKHVTKKKPAN------SKGQNGKRGDADQK 956
+ M+ K +KH+ +KK SK + GK + D++
Sbjct: 905 EKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRE 957
Score = 37.0 bits (84), Expect = 0.11
Identities = 70/330 (21%), Positives = 126/330 (38%), Gaps = 57/330 (17%)
Query: 43 KDLVKYQNSSLKLNDHKKNQFLKMTTFNNKNIFQSTMLTEATTSNSSLDISAIKPNKDGL 102
K L++ +N +++ K++ K NK + E + S++I+ K ++
Sbjct: 928 KHLMEKKNKQSDNSEYSKSEKGK-----NKEKDRELDKKEKSRDKESINITNSKHIQEEK 982
Query: 103 K------NKANYESPGKIFLRMKEKVLRDKQEQPSRNSSLLEPQKSGNNETFTPNRVEKK 156
K NKA +E P L +KEK + + P + +K + + + K
Sbjct: 983 KSSIVDGNKAQHEKP----LSLKEKTKDEPLKTPDGKE---KDKKDKDIDRYKERDKHKD 1035
Query: 157 KLQHTYLCEEKENNKSFQSDDSSLRASVQGVPLESSNNDIF------------LPVKQ-- 202
K+Q L + K + S + N+D+ L ++Q
Sbjct: 1036 KIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWH 1095
Query: 203 ---KIQCQQEKKAPLHNLT-YELPTLNQEQENFLAVEARNKTLTRAQLAKQIFHSKESIV 258
K + +Q++K L N EL ++E+ E++NK LTR++ S E
Sbjct: 1096 KKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSK-------SSEVTD 1148
Query: 259 ATTKSKKDTFVLESVDSADEQFQNTNAETLSTNCIPIKNGSLLMVSDSERTTEGTSQQKV 318
A TK K+ ++V + + N TL + + + SL SE G S + V
Sbjct: 1149 AYTKEKQPK---DAVSNRSQSVDTKNVMTLGKSSF-VSDNSLNRSPRSENEKPGLSSRSV 1204
Query: 319 KEGNGKTVPGETGLPGSMKDTCKIVLATPR 348
+ S +D+C + TPR
Sbjct: 1205 SMIS----------VASSEDSCHTTVTTPR 1224
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 48.1 bits (113), Expect = 5e-05
Identities = 66/314 (21%), Positives = 121/314 (38%), Gaps = 37/314 (11%)
Query: 774 EESETEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQK 833
EE + EK K++ E K + + KE +++T+ I E ETEE E
Sbjct: 518 EEDKAEKTEKKEEEKKDEEEKDEKE---DSKENTKEKDKIDGTAE-ETEERE-------- 565
Query: 834 KARPSVKETLQKSGVRK---------EFPITEAVGSDKTNRHPLECLPGL-------IQD 877
+A P ++T G RK E A + T P P ++
Sbjct: 566 QATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEPPPPLPPPPEPISTEPVET 625
Query: 878 KEWNEKELQKLHCAFASLPKHKPGFWSEVAAAVGSRSPEECQRKYMENPRGKGSQKHVTK 937
W E+E++ A L +H W+ +A VG++S +C+ Y R + +
Sbjct: 626 SRWTEEEME---VAKKGLVEHGRN-WAAIAKMVGTKSEAQCKNFYFNYKRRHNLDNLLQQ 681
Query: 938 KKPANSKGQNGKRGDADQKQTIKITAKVGTLKRKQQMREFLEQLPKDDHDDFFSTTPLQH 997
K S+ +R D Q +++ T + + E E+ P+D + + P +
Sbjct: 682 HKQKTSRKPREER-DVSQCESVASTVSAQEDEDIEASNE--EENPEDSEVE--AVKPSED 736
Query: 998 QRILLPSFQDSEDDDDILPNMDKNPTTPSSVIFPLVKTPQCQHVSPGMLGSINRNDCDKY 1057
S ++E ++ P + P+T S+ P K + + V + SI+ ++
Sbjct: 737 SPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKPAEDESVETQVNDSISAETAEQM 796
Query: 1058 VFRMQKYHKSNGGI 1071
Q++ G +
Sbjct: 797 DVDQQEHSAEEGSV 810
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 46.2 bits (108), Expect = 2e-04
Identities = 45/186 (24%), Positives = 79/186 (42%), Gaps = 15/186 (8%)
Query: 50 NSSLKLNDHKKNQFLKMTTFNNKNIFQSTMLTEATTSNSSL---DISAIKPNKDGLKNKA 106
NS + + H+K+ F K NN N+ ST+ T+ SN L KD +
Sbjct: 3768 NSQMGVRPHEKHDFQKDNFNNNNNLDSSTIQTDNIMSNIVLTEHSAPTCTTEKDNPVKVS 3827
Query: 107 NYESPGKI---FLRMKEKVLRDKQEQPS----RNSSLLEPQKSGNNETFTPNRVEKKKLQ 159
+ + G + +R K+KVL ++Q+ R S L + + +TF PN + K
Sbjct: 3828 SGKKTGVLQGHCVRDKQKVLGEQQKTKELIGIRQKSKLPIKATSPKDTFPPNHMSNTKAS 3887
Query: 160 HTYLCEEKENNKSFQSDDSSLRASVQGVPLESSNNDIFLPVKQKIQCQ---QEKKAPLHN 216
+ E K+ + SS +P+++++ D + V++ Q Q +K
Sbjct: 3888 KMKQVSQSEKTKALTT--SSCVDVKSRIPVKNTHRDNIIAVRKACATQKQGQPEKGKAKQ 3945
Query: 217 LTYELP 222
L +LP
Sbjct: 3946 LPSKLP 3951
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 43.9 bits (102), Expect = 9e-04
Identities = 80/384 (20%), Positives = 151/384 (39%), Gaps = 38/384 (9%)
Query: 482 EKNREKTKQKQKTGRSVRDIRKSMKNDARENQT--DTAQRATTTYDFDCDNLELKSNKHS 539
+K+++ +K +KT + + K D + ++T D + + D L L
Sbjct: 197 QKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDD 256
Query: 540 ESPG--ATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKKL 597
ES A N +N +N +L++ +T +N S+ E K+ K SKK+
Sbjct: 257 ESINFDAWLRNYSQNNSKNY-SLKYTKYTKKDTKKNAKKS--SDAESEDSKDAKKDSKKV 313
Query: 598 KIGERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAINQKK---AYILVTP 654
K + +++ K ++ TE D + +++K ++KK Y T
Sbjct: 314 KKNVKKDDK--KKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTD 371
Query: 655 LKSRKVIEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTFEGHKSKNKEDC 714
+S + R NL KA + + KK S E+ E +S+ E
Sbjct: 372 TESGDAKDARNDSRNLK----KASKNDDKKKDAKKITFSTDS---ESELESKESQKDEKK 424
Query: 715 DERDLLTVNRKIKISNLEKEQMLTSDFKKNTRLLPK-LKKIENQVAMSFYKHQSSPDLSS 773
D++D T N+K + N E+ S+ K +++ K KK + K + + S
Sbjct: 425 DKKDSKTDNKK-SVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAES 483
Query: 774 EESETEKEIKR-----------KAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETE 822
E E++ E+K+ K ++KK +T+ +S++ ++
Sbjct: 484 TEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDT 543
Query: 823 ESENEFYIKQKKARPSVKETLQKS 846
ESE Y +P K+ + +S
Sbjct: 544 ESEESLY------KPGAKKKIDES 561
Score = 35.8 bits (81), Expect = 0.24
Identities = 63/324 (19%), Positives = 129/324 (39%), Gaps = 34/324 (10%)
Query: 644 NQKKAYILVTPLKSRKVIEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTF 703
++KK T +S++++E++ R N + T + + KS + E
Sbjct: 131 SKKKGGSYATNPESKQIVEEKTKRQNEADKT-------PLKSSHENEQSKKSKSSSETNP 183
Query: 704 EGHKSKN-KEDCDERDLLTV--NRKIKISNLEKEQMLTSDFKKNTRLLPKLKKI--ENQV 758
E SK ++C ++D ++K L + D K++ + +I EN +
Sbjct: 184 ESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSL 243
Query: 759 AMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTS--NIPVI 816
+ F D ++ I A ++ N+K + K T+ + N
Sbjct: 244 NVDFLMLVGQSD--------DESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKS 295
Query: 817 LEPETEESENEFYIKQKKARPSVKETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGLIQ 876
+ E+E+S++ KK + +VK+ +K V+K+ T+A D + +
Sbjct: 296 SDAESEDSKDAKK-DSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDER---------K 345
Query: 877 DKEWNEKELQKLHCAFASLPKHKPGFWSEVAAAVGSRSPEECQRKYMENPRGKGSQKHVT 936
D + ++K+L+K K+ +E A +R+ +K +N K K +T
Sbjct: 346 DTKKDKKKLKK-DDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKIT 404
Query: 937 KKKPANSKGQNGKRGDADQKQTIK 960
+ S+ ++ K D+K+ K
Sbjct: 405 FSTDSESELES-KESQKDEKKDKK 427
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 43.1 bits (100), Expect = 0.001
Identities = 47/210 (22%), Positives = 89/210 (42%), Gaps = 15/210 (7%)
Query: 465 ENWKEHIDNFLEQLRAGEKNREKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTY 524
E KE I +++ G K ++ + K D+ K MKN + +A +AT Y
Sbjct: 2433 EKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEK-MKNAKEFEKEISATKATVEY 2491
Query: 525 DFDCDNLELKSNKHSESPGATELNMCHSNCQ--NKPTLRFPDDQVNNTIQNGGGDDLSNQ 582
+ L ++ + S+ T + H++ Q NKP T G G + +
Sbjct: 2492 QKEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPL----------TCGGGSGIVQNTK 2541
Query: 583 ELIGKKEYKMSSKKLKIGERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMA 642
LI K E+ K++ ++ NE++IK + + + +S ++ T +E+ E K +
Sbjct: 2542 ALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKERTLKREAHKQVT 2601
Query: 643 I--NQKKAYILVTPLKSRKVIEQRCMRYNL 670
+ K + T K +++ +C NL
Sbjct: 2602 CENSPKSPKVTGTASKKKQITPSQCKERNL 2631
Score = 32.0 bits (71), Expect = 3.4
Identities = 107/589 (18%), Positives = 228/589 (38%), Gaps = 94/589 (15%)
Query: 468 KEHIDNFLEQLRAGEKNREKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTYDFD 527
+E+I++ L LRA N ++ +T + +++ KND E + A T D +
Sbjct: 493 QENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFE---ALERKTKKDQE 549
Query: 528 CDNLELKSN-----KHSESPGATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSN- 581
+ SN KH+E N S + LR +DQ+ + L N
Sbjct: 550 MQLIHEISNLKNLVKHAEVYNQDLENELSSKVE---LLREKEDQIKKLQEYIDSQKLENI 606
Query: 582 --------QELIGKKEYKMS---SKKLKIGERTNERIIKSQKQETTEELDVSIDILTSRE 630
+ + K+ K + ++ + + + ++S+ E E++ ++ T+ +
Sbjct: 607 KMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMK---ELATTYK 663
Query: 631 QFFSD--------EERKYMAINQKK----AYILVTPLKS---RKVIEQRCMRYNLSAGTI 675
Q +D E +K M ++ +K A+ +T L S KV + L G I
Sbjct: 664 QMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELE-GKI 722
Query: 676 KAVTDFVIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDERDLLTVNRKIKISNLEKEQ 735
+ + E ++ + + + L E ++ + +++ + ++ I EK++
Sbjct: 723 TDLQKELNKEVEENEALREEVILLS---ELKSLPSEVERLRKEIQDKSEELHIITSEKDK 779
Query: 736 MLTSDFKKNTR---LLPKLKKIENQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTK 792
+ + K +R LL ++ K ++ +A + ++S+ + ++K ++ +
Sbjct: 780 LFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEE 839
Query: 793 AGNTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVKETLQ-KSGVRKE 851
+ +V+L K + + L+ E E K ++ + + E Q K +
Sbjct: 840 NERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENR 899
Query: 852 FPITEAVGSDKT-----NRHPLECLPGLIQDKEWNEKELQ-------------------- 886
+ V +KT + LE + L Q+K+ + K+LQ
Sbjct: 900 DSTLQTVEREKTLITEKLQQTLEEVKTLTQEKD-DLKQLQESLQIERDQLKSDIHDTVNM 958
Query: 887 ------KLHCAFASLPKHKPGFWSEVAAAVGSRSPEECQRK-YMENPRGKGSQKH----- 934
+L A SL +H+ E + S+ EE R +ME G+ +
Sbjct: 959 NIDTQEQLRNALESLKQHQ-----ETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMV 1013
Query: 935 -VTKKKPANSKGQNGKRGDADQKQTIKITAKVGTL-KRKQQMREFLEQL 981
+ KK+ +K D + I+ K+ +L + K ++++ LE +
Sbjct: 1014 GIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESV 1062
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 42.4 bits (98), Expect = 0.003
Identities = 86/408 (21%), Positives = 165/408 (40%), Gaps = 60/408 (14%)
Query: 468 KEHIDNFLEQLRAGEKNREKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTYDFD 527
K+ + + L+ + EK QK K ++ D+ K+ K + Q
Sbjct: 859 KDKLSKVSDSLKNSKSEFEKENQKGKA--AILDLEKTCKELKHQLQVQMENTLK------ 910
Query: 528 CDNLELKSNKHSESPGATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGK 587
+ ELK + E + +L + ++ Q + Q NT++ ++ Q I +
Sbjct: 911 -EQKELKKSLEKEKEASHQLKLELNSMQEQLI------QAQNTLKQNEKEEQQLQGNINE 963
Query: 588 KEYKMSSKKLKIGERTNE-RIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAI--N 644
+ KK +I E +I QK E +L LT Q + E+ K + N
Sbjct: 964 LKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQ---LTQAAQELAAEKEKISVLQNN 1020
Query: 645 QKKAYILVTPLKSR---KVIEQRCMRYNLSAGTIK---AVTDFVIPECQ--KKSPISKSM 696
+K+ L+S + E R +L + K A D + Q ++ + + +
Sbjct: 1021 YEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQEL 1080
Query: 697 GTLENTFEGHKSKNKEDCDER--------------DLLTVNRKIKISNLEKEQMLTSDFK 742
T + T E +K ++ ER + VN K K++ +E ++ K
Sbjct: 1081 KTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIE--EIKCRQEK 1138
Query: 743 KNTRLLPKLKKIENQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVH 802
+ T+L +LK +K +S ++++ + + I++K E++ KA + K AV
Sbjct: 1139 EITKLNEELKS---------HKLESIKEITNLKDAKQLLIQQKLELQG-KADSLKAAV-- 1186
Query: 803 LRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVKETLQKSGVRK 850
+ RN + ++ E EE + EF K+ K +KE ++ G++K
Sbjct: 1187 -EQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKE--KEVGMKK 1231
Score = 41.2 bits (95), Expect = 0.006
Identities = 83/426 (19%), Positives = 158/426 (37%), Gaps = 47/426 (11%)
Query: 482 EKNREKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTYDFDCDNLELKSNKHSES 541
E N + + K+K + I+ + TAQRA D L+ + +
Sbjct: 625 ELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELN 684
Query: 542 PGATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKKLKIGE 601
T+L+ + Q+K + +Q KEYK K L + +
Sbjct: 685 KITTQLDQVTAKLQDK-------------------QEHCSQLESHLKEYK--EKYLSLEQ 723
Query: 602 RTNERIIKSQKQETTEELDVSIDILTSREQFFSD--EERKYMAINQKKAYILVTPLKSRK 659
+T E + +K E S+++ S+EQ D ++R+ + +A L L+ K
Sbjct: 724 KTEELEGQIKKLEAD-----SLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEK 778
Query: 660 -VIEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDERD 718
++ + + ++++ + + ++K + + TL E+ + R
Sbjct: 779 EIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQ----ETKIQHEELNNRI 834
Query: 719 LLTVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYKHQSSPDLSSEESET 778
TV K+ +EKE ++T +L ++N + ++Q + +T
Sbjct: 835 QTTVTELQKV-KMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKT 893
Query: 779 EKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPS 838
KE+K + +V+ NT + L+KS L+ E + + Q + +
Sbjct: 894 CKELKHQLQVQME---NTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQN 950
Query: 839 VKETLQKSGVRKEFPITEAVGSDKTNRHPLECLPG-----LIQDKEWNEKELQKLHCAFA 893
KE Q G I E S + + +E L G ++Q E K Q+L A
Sbjct: 951 EKEEQQLQG-----NINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQ 1005
Query: 894 SLPKHK 899
L K
Sbjct: 1006 ELAAEK 1011
Score = 36.2 bits (82), Expect = 0.18
Identities = 37/180 (20%), Positives = 75/180 (41%), Gaps = 10/180 (5%)
Query: 42 VKDLVKYQNSSLKLNDHKKNQFLKMTTFNNKNIFQSTMLTEATTSNSSLDISAIKPNKDG 101
++D+ K ++ K ++K++ ++ + + T L E S+ I I
Sbjct: 1105 LQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEIT----N 1160
Query: 102 LKNKANYESPGKIFLRMKEKVLRDKQEQPSRNSSLLEPQKSGNNETFTPNRVEKKKLQHT 161
LK+ K+ L+ K L+ EQ RN +L+ Q E +EK+ H+
Sbjct: 1161 LKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHS 1220
Query: 162 YLCEEKENNKSFQSDDSSLRASVQGVPLESSNNDIFLPVKQKIQCQQEKKAPLHNLTYEL 221
+ E++ K + +++ L + + N+ VK++ Q Q + + L T +L
Sbjct: 1221 EIKEKEVGMKKHEENEAKLTMQITAL------NENLGTVKKEWQSSQRRVSELEKQTDDL 1274
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 42.4 bits (98), Expect = 0.003
Identities = 53/265 (20%), Positives = 100/265 (37%), Gaps = 31/265 (11%)
Query: 696 MGTLENTFEGHKSKNKEDCDERDLLTVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIE 755
+G+L++T E H K+ D ++ S +++ + ++ K N L + K E
Sbjct: 586 VGSLKSTPENHPETPKKKSDP--------ELSKSEMKQSESRLAESKPNENRLVETKSSE 637
Query: 756 NQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPV 815
N++ + +L ES T + + ++ + + K + + + +N
Sbjct: 638 NKLETKV--ETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGR--- 692
Query: 816 ILEPETEESENEFYIKQKKARPSVKETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGLI 875
ET +S E ++ ++RP + QKS E P + G +T + E P
Sbjct: 693 ---SETTKSRPETPKQKGESRPETPK--QKSDGHPETPKQKGDGRPETPKQKGESRPETP 747
Query: 876 QDKEWNEKELQKLHCAFASLPKHKPGFWSEVAAAVGSRSPEECQRKY---MENPRGKGSQ 932
+ K E PKH+ + + PE + K ++PR K +
Sbjct: 748 KQKNEGRPET----------PKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSER 797
Query: 933 KHVTKKKPANSKGQNGKRGDADQKQ 957
K++P R D D KQ
Sbjct: 798 AEALKQRPDGRSVSESLRRDHDNKQ 822
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 42.4 bits (98), Expect = 0.003
Identities = 53/265 (20%), Positives = 100/265 (37%), Gaps = 31/265 (11%)
Query: 696 MGTLENTFEGHKSKNKEDCDERDLLTVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIE 755
+G+L++T E H K+ D ++ S +++ + ++ K N L + K E
Sbjct: 586 VGSLKSTPENHPETPKKKSDP--------ELSKSEMKQSESRLAESKPNENRLVETKSSE 637
Query: 756 NQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPV 815
N++ + +L ES T + + ++ + + K + + + +N
Sbjct: 638 NKLETKV--ETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGR--- 692
Query: 816 ILEPETEESENEFYIKQKKARPSVKETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGLI 875
ET +S E ++ ++RP + QKS E P + G +T + E P
Sbjct: 693 ---SETTKSRPETPKQKGESRPETPK--QKSDGHPETPKQKGDGRPETPKQKGESRPETP 747
Query: 876 QDKEWNEKELQKLHCAFASLPKHKPGFWSEVAAAVGSRSPEECQRKY---MENPRGKGSQ 932
+ K E PKH+ + + PE + K ++PR K +
Sbjct: 748 KQKNEGRPET----------PKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSER 797
Query: 933 KHVTKKKPANSKGQNGKRGDADQKQ 957
K++P R D D KQ
Sbjct: 798 AEALKQRPDGRSVSESLRRDHDNKQ 822
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 41.2 bits (95), Expect = 0.006
Identities = 69/324 (21%), Positives = 127/324 (39%), Gaps = 30/324 (9%)
Query: 479 RAGEKNREKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTYDFDCDNLELKSNKH 538
+ EK+ E + K+ R+V ++ ++ DA + A R + D + +E++ +
Sbjct: 1576 KIAEKDEEIEQLKRNYQRTVETMQSAL--DAEVRSRNEAIRLKKKMEGDLNEIEIQLSHA 1633
Query: 539 SESPGATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKKLK 598
+ T ++ Q K T DD + G +DL Q I ++ + +++
Sbjct: 1634 NRQAAETLKHLRSVQGQLKDTQLHLDDALR------GQEDLKEQLAIVERRANLLQAEVE 1687
Query: 599 IGERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAINQKKAYILVTPLKSR 658
T E+ +++K E LD + + Q S + +KK + L+S
Sbjct: 1688 ELRATLEQTERARKLAEQELLDSNERVQLLHTQNTS------LIHTKKKLETDLMQLQSE 1741
Query: 659 KVIEQRCMRYNLSAGTIKAVTD--FVIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDE 716
R R N KA+TD + E +K+ S + ++ E + DE
Sbjct: 1742 VEDASRDAR-NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1800
Query: 717 RDLLTVN------RKIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYKHQSS-- 768
+ L + +K++ E E L + KKNT + L+K E +V Y+ +
Sbjct: 1801 AEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRK 1860
Query: 769 -----PDLSSEESETEKEIKRKAE 787
DL + K KR+AE
Sbjct: 1861 NVLRLQDLVDKLQVKVKSYKRQAE 1884
Score = 31.2 bits (69), Expect = 5.8
Identities = 49/236 (20%), Positives = 97/236 (41%), Gaps = 26/236 (11%)
Query: 609 KSQKQETT--EELDVSIDILTSREQFFSDEERKYMAINQKKAYI-LVTPLKSRKVI--EQ 663
+++K+ T EE + D L E + E K + + Q+K + L +S ++ E+
Sbjct: 845 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEE 904
Query: 664 RCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDERDLLTVN 723
RC + + ++A V + + I+ + K K +++C E +
Sbjct: 905 RCDQLIKAKFQLEAKIKEVTERAEDEEEINAEL-------TAKKRKLEDECSELKKDIDD 957
Query: 724 RKIKISNLEKEQMLTSDFKKN-TRLLPKL-----KKIENQVAMSFYKHQSSPDLSSEESE 777
++ ++ +EKE+ T + KN T L L K + A+ Q+ DL +EE +
Sbjct: 958 LELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDK 1017
Query: 778 TEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQK 833
K K+++ ++ V L S + V LE + E + + Q+
Sbjct: 1018 VNSLNKTKSKL--------EQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQE 1065
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 40.4 bits (93), Expect = 0.010
Identities = 71/344 (20%), Positives = 128/344 (37%), Gaps = 37/344 (10%)
Query: 684 PECQKKSPISKSMGTLENTFEGHKSKNKEDCD-ERDLLTVNRKIKISNLEKEQMLTSDFK 742
PEC S+SM + + +E + K K+D D ++ T N+ I + + S
Sbjct: 466 PECPVLKRSSESMENINSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTNKMKSPET 525
Query: 743 KNTRLLPKLKKIENQVAMSFYK--HQSSPDLSSEESETEKEI---KRKAEVKKTKAGNTK 797
K +L P + N F + +P + E E+E++I KRK ++ K
Sbjct: 526 KQRKLSPLRLSVSNNQEPDFIDDIEEKTPISNEVEMESEEQIAERKRKMTREERKMEAIL 585
Query: 798 EAVVHLRK-STRNTSNIPVILEPETE----------ESENEFYIKQKKARPSVKET---L 843
+A L K R + I +TE S+ E +Q K + K T +
Sbjct: 586 QAFARLEKREKRREQALERISTAKTEVKTECKDTQIVSDAEVIQEQAKEENASKPTPAKV 645
Query: 844 QKSGVRKEFPITEAVGSDKTNRHPLECLPGLIQ----DKEWNEKELQKLHCAFASLPKHK 899
++ RK F + + RH + IQ D E ++ + P+ +
Sbjct: 646 NRTKQRKSFSRSRTHIGQQRRRHRTVSMCSDIQPSSPDIEVTSQQNDIENTVLTIEPETE 705
Query: 900 PGFWSEVAAAVGSRSPEECQRKYMENPRGKGSQKHVTKKKPANSKGQNGKRGDADQKQTI 959
+E+ + +C KY + ++KH+ + + + GK D ++ +
Sbjct: 706 TAL-AEIITETEVPALNKCPTKYPK------TKKHLVNEWLSEKNEKTGKPSDGLSERPL 758
Query: 960 KITAKVGTLKRKQQMREFLEQLPKDDHDDFFSTTPLQHQRILLP 1003
+IT L + L LP + +TP + R P
Sbjct: 759 RITTDPEVLATQ------LNSLPGLTYSPHVYSTPKHYIRFTSP 796
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 40.4 bits (93), Expect = 0.010
Identities = 71/344 (20%), Positives = 128/344 (37%), Gaps = 37/344 (10%)
Query: 684 PECQKKSPISKSMGTLENTFEGHKSKNKEDCD-ERDLLTVNRKIKISNLEKEQMLTSDFK 742
PEC S+SM + + +E + K K+D D ++ T N+ I + + S
Sbjct: 466 PECPVLKRSSESMENINSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTNKMKSPET 525
Query: 743 KNTRLLPKLKKIENQVAMSFYK--HQSSPDLSSEESETEKEI---KRKAEVKKTKAGNTK 797
K +L P + N F + +P + E E+E++I KRK ++ K
Sbjct: 526 KQRKLSPLRLSVSNNQEPDFIDDIEEKTPISNEVEMESEEQIAERKRKMTREERKMEAIL 585
Query: 798 EAVVHLRK-STRNTSNIPVILEPETE----------ESENEFYIKQKKARPSVKET---L 843
+A L K R + I +TE S+ E +Q K + K T +
Sbjct: 586 QAFARLEKREKRREQALERISTAKTEVKTECKDTQIVSDAEVIQEQAKEENASKPTPAKV 645
Query: 844 QKSGVRKEFPITEAVGSDKTNRHPLECLPGLIQ----DKEWNEKELQKLHCAFASLPKHK 899
++ RK F + + RH + IQ D E ++ + P+ +
Sbjct: 646 NRTKQRKSFSRSRTHIGQQRRRHRTVSMCSDIQPSSPDIEVTSQQNDIENTVLTIEPETE 705
Query: 900 PGFWSEVAAAVGSRSPEECQRKYMENPRGKGSQKHVTKKKPANSKGQNGKRGDADQKQTI 959
+E+ + +C KY + ++KH+ + + + GK D ++ +
Sbjct: 706 TAL-AEIITETEVPALNKCPTKYPK------TKKHLVNEWLSEKNEKTGKPSDGLSERPL 758
Query: 960 KITAKVGTLKRKQQMREFLEQLPKDDHDDFFSTTPLQHQRILLP 1003
+IT L + L LP + +TP + R P
Sbjct: 759 RITTDPEVLATQ------LNSLPGLTYSPHVYSTPKHYIRFTSP 796
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 40.4 bits (93), Expect = 0.010
Identities = 47/227 (20%), Positives = 96/227 (42%), Gaps = 27/227 (11%)
Query: 732 EKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYKHQSSP-DLSSEESETEKEIKRKAEVKK 790
+K + S +++ R K ++ + Q + Q P SS+E + EKE +++AE ++
Sbjct: 474 KKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEE 533
Query: 791 TKAGNTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVKETLQKSGVRK 850
K + L++ T +TS +N+ +K+A S S R+
Sbjct: 534 EKPEVENDKEDLLKEKTDDTSG-----------EDND----EKEAVASKGRKTANSQGRR 578
Query: 851 EFPITEAVGSDKTNRHPLECLPG-------LIQDKEWNEKELQKLHCAFASLPKHKPGFW 903
+ IT ++ ++ + + L + W E+E++ A L +H W
Sbjct: 579 KGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMET---AKKGLLEHGRN-W 634
Query: 904 SEVAAAVGSRSPEECQRKYMENPRGKGSQKHVTKKKPANSKGQNGKR 950
S +A VGS++ +C+ Y + + + + + K K +N +R
Sbjct: 635 SAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARR 681
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 40.4 bits (93), Expect = 0.010
Identities = 47/227 (20%), Positives = 96/227 (42%), Gaps = 27/227 (11%)
Query: 732 EKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYKHQSSP-DLSSEESETEKEIKRKAEVKK 790
+K + S +++ R K ++ + Q + Q P SS+E + EKE +++AE ++
Sbjct: 474 KKNENYKSLVRRSYRRRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEE 533
Query: 791 TKAGNTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVKETLQKSGVRK 850
K + L++ T +TS +N+ +K+A S S R+
Sbjct: 534 EKPEVENDKEDLLKEKTDDTSG-----------EDND----EKEAVASKGRKTANSQGRR 578
Query: 851 EFPITEAVGSDKTNRHPLECLPG-------LIQDKEWNEKELQKLHCAFASLPKHKPGFW 903
+ IT ++ ++ + + L + W E+E++ A L +H W
Sbjct: 579 KGRITRSMANEANSEEAITPQQSAELASMELNESSRWTEEEMET---AKKGLLEHGRN-W 634
Query: 904 SEVAAAVGSRSPEECQRKYMENPRGKGSQKHVTKKKPANSKGQNGKR 950
S +A VGS++ +C+ Y + + + + + K K +N +R
Sbjct: 635 SAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARR 681
>gi|45439370 TAO kinase 1 [Homo sapiens]
Length = 1001
Score = 39.7 bits (91), Expect = 0.016
Identities = 53/266 (19%), Positives = 112/266 (42%), Gaps = 35/266 (13%)
Query: 587 KKEYKMSSKKLKIGERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAINQK 646
K+EYK+ ++LK N+ K +KQE + +I + F ++EE +
Sbjct: 556 KREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENI------QHFQAEEEANLLR---- 605
Query: 647 KAYILVTPLKSRKVIEQRCMRY--NLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTFE 704
+ R+ +E C R+ + G D V E K+ ++ LE+
Sbjct: 606 ---------RQRQYLELECRRFKRRMLLGRHNLEQDLVREELNKR----QTQKDLEHAML 652
Query: 705 GHKSKNKEDCDERDLLTVNR-KIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFY 763
+ ++ ++ + R L T+ + + ++ L+ + LT+ + N R + +++ + M
Sbjct: 653 LRQHESMQELEFRHLNTIQKMRCELIRLQHQTELTNQLEYNKR---RERELRRKHVMEV- 708
Query: 764 KHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETEE 823
Q L S+E + +K+ + + K + K HL ++T + + +L+ EE
Sbjct: 709 -RQQPKSLKSKELQIKKQFQ---DTCKIQTRQYKALRNHLLETTPKSEH-KAVLKRLKEE 763
Query: 824 SENEFYIKQKKARPSVKETLQKSGVR 849
+ I ++ S+ E L +R
Sbjct: 764 QTRKLAILAEQYDHSINEMLSTQALR 789
Score = 33.9 bits (76), Expect = 0.90
Identities = 55/250 (22%), Positives = 96/250 (38%), Gaps = 21/250 (8%)
Query: 113 KIFLRMKEKVLR-DKQEQPSRNSSLLEPQK-------SGNNETFTPNRVEKKKLQHTYLC 164
K+ M E LR DK + RN+ E +K + E + EKK QH
Sbjct: 484 KLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQAAMEKEAKVMSNEEKKFQQHIQAQ 543
Query: 165 EEKENNKSFQSDDSSLRASVQGVPLESSNNDIFLPVKQKIQCQQEKKAPL-HNLTYELPT 223
++KE N +S + + + E + N P K+K + ++K + H E
Sbjct: 544 QKKELNSFLESQKREYKLRKEQLKEELNENQS-TPKKEKQEWLSKQKENIQHFQAEEEAN 602
Query: 224 LNQEQENFLAVEA----RNKTLTRAQLAKQIFHSKESIVATTKSKKDTFVLESVDSADE- 278
L + Q +L +E R L R L + + + + T K + +L +S E
Sbjct: 603 LLRRQRQYLELECRRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLRQHESMQEL 662
Query: 279 QFQNTNA-ETLSTNCIPIKN-----GSLLMVSDSERTTEGTSQQKVKEGNGKTVPGETGL 332
+F++ N + + I +++ L ER +V++ E +
Sbjct: 663 EFRHLNTIQKMRCELIRLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKSLKSKELQI 722
Query: 333 PGSMKDTCKI 342
+DTCKI
Sbjct: 723 KKQFQDTCKI 732
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 39.7 bits (91), Expect = 0.016
Identities = 76/419 (18%), Positives = 167/419 (39%), Gaps = 65/419 (15%)
Query: 472 DNFLEQLRAGEKNREKTKQKQK---TGRSVRDIRKSMKNDARENQTDTAQRATTTYDFDC 528
+N + LR G K + K K S RD+ K+ KND+ + AT+ + +
Sbjct: 863 ENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEV 922
Query: 529 DNLELKSNKHSESPGATEL---NMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELI 585
+ +K ++S T L N + + + + + +N+ N G
Sbjct: 923 SEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRG---------- 972
Query: 586 GKKEYKMSSKKLKIGERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAINQ 645
+K K G + N K+E T+++ +E+ +++K+ A +
Sbjct: 973 -------KPQKHKHGSKEN------LKREHTKKV---------KEKLKGKKDKKHKAPKR 1010
Query: 646 KKAYILVTPLKSRKVIEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTL-ENTFE 704
K+A+ PL+ + E+ + D + + K+ +S++ T+ +N +
Sbjct: 1011 KQAFHWQPPLEFGEEEEEE-------------IDDKQVTQESKEKKVSENNETIKDNILK 1057
Query: 705 GHKSKNKEDCDERDLLTVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYK 764
KS ++ + D +TV+ S+L++ T D K + L EN + +
Sbjct: 1058 TEKSSEEDLSGKHDTVTVS-----SDLDQ---FTKDDSKLSISPTALNTEENVACLQNIQ 1109
Query: 765 H--QSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETE 822
H +S P+ + +T+ ++ + + A E L + +T +I ++L+ +
Sbjct: 1110 HVEESVPNGVEDVLQTDDNMEICTPDRSSPA--KVEETSPLGNARLDTPDINIVLKQDMA 1167
Query: 823 ESENEFYIKQKKARPSVKETLQKSGVRKEFPITEAVGSDKTNRHPL-ECLPGLIQDKEW 880
+ + ++++ S + L + G + + A + T + + E + DK+W
Sbjct: 1168 TEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDKKW 1226
>gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1
[Homo sapiens]
Length = 621
Score = 39.7 bits (91), Expect = 0.016
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 833 KKARPSVKETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGLIQD-KEWNEKELQKLHCA 891
+K P K+ + K K F V N P E G D W +E + L A
Sbjct: 507 QKLDPHQKDDINKKAFDK-FKKEHGVVPQADNATPSERFEGPYTDFTPWTTEEQKLLEQA 565
Query: 892 FASLPKHKPGFWSEVAAAVGSRSPEECQRKYME 924
+ P + P W ++A AV R+ ++C ++Y E
Sbjct: 566 LKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKE 598
>gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 2
[Homo sapiens]
Length = 568
Score = 39.7 bits (91), Expect = 0.016
Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 833 KKARPSVKETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGLIQD-KEWNEKELQKLHCA 891
+K P K+ + K K F V N P E G D W +E + L A
Sbjct: 454 QKLDPHQKDDINKKAFDK-FKKEHGVVPQADNATPSERFEGPYTDFTPWTTEEQKLLEQA 512
Query: 892 FASLPKHKPGFWSEVAAAVGSRSPEECQRKYME 924
+ P + P W ++A AV R+ ++C ++Y E
Sbjct: 513 LKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKE 545
Score = 35.8 bits (81), Expect = 0.24
Identities = 52/261 (19%), Positives = 98/261 (37%), Gaps = 14/261 (5%)
Query: 700 ENTFEGHKSKNKEDC-DERDLLTVNRKIKISNLEKEQM--LTSDFKKNTRLLPKLKKIEN 756
E ++ + K K +C DER + + + +KE+M + + P++KK +
Sbjct: 226 EFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKE 285
Query: 757 QVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVI 816
+ + + + + + KE +R+AE++ + KE + R + ++
Sbjct: 286 EEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKE-----EEEVRQQA---LL 337
Query: 817 LEPETEESENEFYIKQKKARPSVKETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGLIQ 876
+ E + + +++K R S K +RKE EA + G
Sbjct: 338 AKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNG 397
Query: 877 DKEWNEKELQKLHCAFASLPKHKPGFWSEVAAAVGSRSPEECQRKYMENPRGKGSQKHVT 936
K W+E +LQ L A P W +A + S +R + G K +
Sbjct: 398 SKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKD---VIGKAKSLQ 454
Query: 937 KKKPANSKGQNGKRGDADQKQ 957
K P N K D +K+
Sbjct: 455 KLDPHQKDDINKKAFDKFKKE 475
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 39.3 bits (90), Expect = 0.021
Identities = 84/438 (19%), Positives = 170/438 (38%), Gaps = 100/438 (22%)
Query: 560 LRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKKLKIGERTNERI------------ 607
L+ + Q+ N IQ S+ E+I +KE ++ KLK+ + ++ R
Sbjct: 1017 LKKENQQIINQIQE------SHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAE 1070
Query: 608 ------------------IKSQKQETTEELDVSIDILTSREQFFSD-------EERKYMA 642
+KS ++ TE L I L + Q ++ E R M
Sbjct: 1071 TDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMT 1130
Query: 643 INQKKAYILVTPLKSRKVIEQRCMRYNLSAGTIKAVTDFVIPECQKK------SPISKSM 696
I + + ++ L SR E ++ L+ T F I + K+ S + +
Sbjct: 1131 IEKDQC---ISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSEL 1187
Query: 697 GTLENTFEGHKSKNKE---------DCDERDLLTVNRK-----IKISNLEKEQMLTSDFK 742
LE + ++ +E + D + L++ + I+ N EK++ + + K
Sbjct: 1188 SALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALK 1247
Query: 743 K--------NTRLLPKLKKIENQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAG 794
+ LL K+K +ENQ+A S + D SS +E +++++ + KA
Sbjct: 1248 EFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEE------KAK 1301
Query: 795 NTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSV--------KETLQKS 846
++ ++ N+ L E + + N ++K + ++ K T+Q+
Sbjct: 1302 FLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQ 1361
Query: 847 GVRKEFPITEAVGSDKTNRHPLECLPGLIQDKEWNEKELQKLHCAFASLPKHKPGFWSEV 906
++ + E++ D+ L+++K+ E+E+ KL + + +P E+
Sbjct: 1362 --ERDKDLIESLSEDRAR---------LLEEKKKLEEEVSKLRSS-SFVPSPYVATAPEL 1409
Query: 907 AAAVGSRSPEECQRKYME 924
A P E R +E
Sbjct: 1410 YGACAPELPGESDRSAVE 1427
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 39.3 bits (90), Expect = 0.021
Identities = 84/438 (19%), Positives = 170/438 (38%), Gaps = 100/438 (22%)
Query: 560 LRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKKLKIGERTNERI------------ 607
L+ + Q+ N IQ S+ E+I +KE ++ KLK+ + ++ R
Sbjct: 1017 LKKENQQIINQIQE------SHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAE 1070
Query: 608 ------------------IKSQKQETTEELDVSIDILTSREQFFSD-------EERKYMA 642
+KS ++ TE L I L + Q ++ E R M
Sbjct: 1071 TDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMT 1130
Query: 643 INQKKAYILVTPLKSRKVIEQRCMRYNLSAGTIKAVTDFVIPECQKK------SPISKSM 696
I + + ++ L SR E ++ L+ T F I + K+ S + +
Sbjct: 1131 IEKDQC---ISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSEL 1187
Query: 697 GTLENTFEGHKSKNKE---------DCDERDLLTVNRK-----IKISNLEKEQMLTSDFK 742
LE + ++ +E + D + L++ + I+ N EK++ + + K
Sbjct: 1188 SALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALK 1247
Query: 743 K--------NTRLLPKLKKIENQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAG 794
+ LL K+K +ENQ+A S + D SS +E +++++ + KA
Sbjct: 1248 EFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEE------KAK 1301
Query: 795 NTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSV--------KETLQKS 846
++ ++ N+ L E + + N ++K + ++ K T+Q+
Sbjct: 1302 FLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQ 1361
Query: 847 GVRKEFPITEAVGSDKTNRHPLECLPGLIQDKEWNEKELQKLHCAFASLPKHKPGFWSEV 906
++ + E++ D+ L+++K+ E+E+ KL + + +P E+
Sbjct: 1362 --ERDKDLIESLSEDRAR---------LLEEKKKLEEEVSKLRSS-SFVPSPYVATAPEL 1409
Query: 907 AAAVGSRSPEECQRKYME 924
A P E R +E
Sbjct: 1410 YGACAPELPGESDRSAVE 1427
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 39.3 bits (90), Expect = 0.021
Identities = 90/479 (18%), Positives = 171/479 (35%), Gaps = 44/479 (9%)
Query: 486 EKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTYDFDCDNLELKSNKHSESPGAT 545
+ + K++T + D KS + E +TA ++ D C E+K+
Sbjct: 244 DTSTDKERTSEDMADKEKSTADSGGEG-LETAPKSEEFSDLPCPVEEIKNYTKE------ 296
Query: 546 ELNMCHSNC--QNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKK----LKI 599
H+N NK + +Q N + G SN++ KKE K ++K K
Sbjct: 297 -----HNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKK 351
Query: 600 GERTNE-RIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAINQKKAYILVTPLKSR 658
E T + + K K++ E L + + +++ + + + I+ + + S
Sbjct: 352 SEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSV 411
Query: 659 KVIEQRCMRYNLSAGTIKAVT---DFVIPECQKKSPISKSMGTLENTFEG---------- 705
+ + + + + + + ++K+ +K+ ++ EG
Sbjct: 412 HTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYV 471
Query: 706 HKS--KNKEDCDERDLLTVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFY 763
HK +K D D LTV ++ + EKE+ L +L K K+ + S
Sbjct: 472 HKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKT 531
Query: 764 KHQSSPDLSSEESETEKEIKRKAEVKKT-KAGNTKEAVVHLRKSTRNTSNIPVILEPETE 822
K Q + EES T+ + A +K+ K E V L K + S E
Sbjct: 532 KGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSR-----NVEEN 586
Query: 823 ESENEFYIKQKKARPSVKETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGL-IQDKEWN 881
+ + Y + K E +K + + + ++ L + D+ N
Sbjct: 587 SKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKN 646
Query: 882 EKELQKLHCAFASLPKHKPGFWSEVAAAVGSRSPEE---CQRKYMENPRGKGSQKHVTK 937
E +L++ H S P G E R E C + + ++KH+ K
Sbjct: 647 ESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKK 705
Score = 38.1 bits (87), Expect = 0.048
Identities = 51/245 (20%), Positives = 95/245 (38%), Gaps = 19/245 (7%)
Query: 59 KKNQFLKMTTFNNKNIFQSTMLTEATTSNSSLDISAIKPNKDGLKN---KANYESPGKIF 115
K+ + LK+ + N N T + D S I + DGL + + + S F
Sbjct: 367 KEVESLKLPSEKNSN-------KAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSF 419
Query: 116 LRMKEK--VLRDKQEQPSRNSSLLEPQKSGNNETFTPNRVE--KKKLQHTYLCEEKENNK 171
E+ V D E+ S E K +T T + E K ++H Y+ + +K
Sbjct: 420 EEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSK 479
Query: 172 SFQSDDSSLRASVQGVPLESSNNDIFLPVKQKIQCQQEKKAPLHNLTYELPTLNQEQENF 231
+ D L + + + L + + +EK+ T T Q + +
Sbjct: 480 YYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSV 539
Query: 232 LAVEARNKTLT-RAQLAKQIFHSKE----SIVATTKSKKDTFVLESVDSADEQFQNTNAE 286
E+ K+L +A K++ ++ + + K KKD+ +E +Q++ + E
Sbjct: 540 DLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKE 599
Query: 287 TLSTN 291
TL T+
Sbjct: 600 TLKTS 604
Score = 31.2 bits (69), Expect = 5.8
Identities = 77/334 (23%), Positives = 127/334 (38%), Gaps = 44/334 (13%)
Query: 483 KNREKTKQKQKTGRSVRDIRKSMKN--DARENQTDTAQRATTTYDFDCDNLELKSNKH-- 538
KN K +++ K S I + ++ D R+ + + T + LK+ KH
Sbjct: 645 KNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLK 704
Query: 539 ---SESPGATEL--NMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMS 593
SE+P L S+ + + P + + GD + + E S
Sbjct: 705 KDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTG--DETELHSS 762
Query: 594 SKKLKIGERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAINQKKA---YI 650
K LK+ E I+ Q Q+T +S D T R+ +E + + K YI
Sbjct: 763 EKGLKVEEN-----IQKQSQQTK----LSSDDKTERKSKHRNERKLSVLGKDGKPVSEYI 813
Query: 651 LVTPLKSRKVIEQRCMRYNLSAGTIKAV------TDFVIPECQKKSPISKSMG-TLENTF 703
+ T RK E LSA KA +D I QK S SK G TL+
Sbjct: 814 IKTDENVRK--ENNKKERRLSAEKTKAEHKSRRSSDSKI---QKDSLGSKQHGITLQRRS 868
Query: 704 EGHKSKNKEDCDERDL--------LTVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIE 755
E + S++K D D ++ + K + +L +E+++ K K+ + E
Sbjct: 869 ESY-SEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETE 927
Query: 756 NQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVK 789
Q + PD E + E +RK++V+
Sbjct: 928 LQEGATKQATTPKPDKEKNTEENDSEKQRKSKVE 961
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 38.9 bits (89), Expect = 0.028
Identities = 99/479 (20%), Positives = 180/479 (37%), Gaps = 83/479 (17%)
Query: 532 ELKSNKHSESPGATELNMCHSNCQN-KPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEY 590
E S K + P E+ C ++ ++ K ++ P Q I+ GG S++ I +K
Sbjct: 311 ESDSFKENVKPIKVEVKECRADPKDTKSSMEKPVAQEPERIEFGGNIKSSHE--ITEKST 368
Query: 591 KMSSKKLKIGERTNERIIKSQKQETTEELDVSID-----ILTSREQFFSDEERKYMAINQ 645
+ ++KLK ++ + +K ++ + +++ D + +T ++F DE ++ +
Sbjct: 369 E-ETEKLK-NDQQAKIPLKKREIKLSDDFDSPVKGPLCKSVTPTKEFLKDEIKQEEETCK 426
Query: 646 KKAYILVTPLKSRKVIEQRCMRYNLSAGTIKAVTDFVIPECQKKSPI-SKSMGTLENTFE 704
+ + I + ++++ V+D + K PI +K T E ++
Sbjct: 427 RISTITALGHEGKQLVNGE-------------VSDERVAPNFKTEPIETKFYETKEESYS 473
Query: 705 GHKSKN--KEDCDERDLLTVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAM-- 760
K +N E L +V +K LEKE T+ +K+ + +I +Q A
Sbjct: 474 PSKDRNIITEGNGTESLNSVITSMKTGELEKE---TAPLRKDADSSISVLEIHSQKAQIE 530
Query: 761 ---------SFYKHQSSPDLSSE------ESETEKEIKRKAEVKKTKAGNTKEAVVHLRK 805
S + + DLSS+ ES T K ++ + KK K E + L K
Sbjct: 531 EPDPPEMETSLDSSEMAKDLSSKTALSSTESCTMKGEEKSPKTKKDKRPPILECLEKLEK 590
Query: 806 STRNTSNIPVI-LEPETEESENEFYIKQKKARPSVKETLQKSGVRK------------EF 852
S + + L P EE +K P ET S + E
Sbjct: 591 SKKTFLDKDAQRLSPIPEEVPKSTLESEKPGSPEAAETSPPSNIIDHCEKLASEKEVVEC 650
Query: 853 PITEAVGSDKTNRHPLECLPGLIQDKEWNEKELQKLHCAFASLPKHKPGFWSEVAAAVGS 912
T VG + LE L +D E+ + E+ L A S G
Sbjct: 651 QSTSTVGGQSVKKVDLETLK---EDSEFTKVEMDNLDNAQTS----------------GI 691
Query: 913 RSPEECQRKYMENPRGKGSQKHVTKKKPANSKGQNGKRGDADQKQTIKITAKVGTLKRK 971
P E + K K+ + + +N + QK+ IK+T ++ + K+K
Sbjct: 692 EEPSETKGSMQ-----KSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKKK 745
Score = 30.8 bits (68), Expect = 7.6
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 5/62 (8%)
Query: 766 QSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETEESE 825
+ SP L EE++ E+E ++ E K+++ ++E + L R+T+N +LE T + E
Sbjct: 225 RESPSLEDEETKKEEETPKQEEQKESEKMKSEEQPMDL--ENRSTAN---VLEETTVKKE 279
Query: 826 NE 827
E
Sbjct: 280 KE 281
Score = 30.8 bits (68), Expect = 7.6
Identities = 34/168 (20%), Positives = 76/168 (45%), Gaps = 26/168 (15%)
Query: 682 VIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDERDLLTVNRKIKISNLEKEQMLTSDF 741
+I C+K + + + + G +S K D + + K+++ NL+ Q TS
Sbjct: 634 IIDHCEKLASEKEVVECQSTSTVGGQSVKKVDLETLKEDSEFTKVEMDNLDNAQ--TSGI 691
Query: 742 KKNTRLLPKLKKIENQVAMSFYKHQSSPD---LSSEESETEKEIKRKAEVKKTKAGNTKE 798
++ + ++K S +K++ P+ +SE +E E ++K +K T
Sbjct: 692 EEPSETKGSMQK-------SKFKYKLVPEEETTASENTEITSE-RQKEGIKLT------- 736
Query: 799 AVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVKETLQKS 846
+ + + + P +LEPE ++ + E +++ + +V TL++S
Sbjct: 737 --IRISSRKKKPDSPPKVLEPENKQEKTE----KEEEKTNVGRTLRRS 778
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 38.9 bits (89), Expect = 0.028
Identities = 62/288 (21%), Positives = 110/288 (38%), Gaps = 23/288 (7%)
Query: 689 KSPISKSMGTLENTFEGHKSKNKEDCDERDLLTVNRKIKISNLEKEQMLT---SDFKKNT 745
KSP+ + T E KS KE+ + K K +++ + T + +
Sbjct: 723 KSPVKEEAKTPEKA----KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA 778
Query: 746 RLLPKLKKIENQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVHLRK 805
P+ K + + + SP L + EKEI +K EVK K V +++
Sbjct: 779 DKFPEKAKSPVKEEVKSPEKAKSP-LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKE 837
Query: 806 STRNTSNIPVILEPETEE---SENEFYIKQKKARPSVKETLQKSGVRKEFPITEAVGSDK 862
+ P+TEE S+ E K++ +P V+E + + + + EA +
Sbjct: 838 PPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 897
Query: 863 TNRH----PLECLPGLIQDKE----WNEKELQKLHCAFASLPKHKPGFWSEVAAAVGSRS 914
++ P + P ++ KE + E+ K A + + AA +
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT 957
Query: 915 PEECQRKYMENPRGKGSQKHVTK---KKPANSKGQNG-KRGDADQKQT 958
EE +K E P+ + K K K+P+ K + K DQK +
Sbjct: 958 KEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDS 1005
Score = 34.7 bits (78), Expect = 0.53
Identities = 40/198 (20%), Positives = 86/198 (43%), Gaps = 9/198 (4%)
Query: 82 EATTSNSSLDISAIKPNKDGLKNKANYESPGKIFLRMKEKVLRDKQEQPSRNSSLLEPQK 141
EA + A P K+ +K+ +SP K + EK + K+E S +PQ+
Sbjct: 773 EARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQE 832
Query: 142 SGNNETFTPNRVEKKKLQHTYLCEEKENNKSFQSDDSSLRASVQGVPLESSNNDIFLPVK 201
E P + E++K T EEK+++K +++ + + + E + P +
Sbjct: 833 VKVKE--PPKKAEEEKAPATPKTEEKKDSK---KEEAPKKEAPKPKVEEKKEPAVEKPKE 887
Query: 202 QKIQCQQEKKAPLHNLTYELPTLNQEQENFLAVEARNKTLTRAQLAKQIFHSKESIVATT 261
K++ ++E+ ++PT +E + V+ K + ++AK+ ++ +
Sbjct: 888 SKVEAKKEEAED----KKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943
Query: 262 KSKKDTFVLESVDSADEQ 279
++K E D+ +E+
Sbjct: 944 PAEKKEAAPEKKDTKEEK 961
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 38.5 bits (88), Expect = 0.036
Identities = 34/183 (18%), Positives = 72/183 (39%), Gaps = 8/183 (4%)
Query: 731 LEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKK 790
LE + + + +NT LL + KK+E VA + Q + +E + +E +KA ++
Sbjct: 1719 LEATERINLFYTQNTSLLSQKKKLEADVA----RMQKEAEEVVQECQNAEEKAKKAAIEA 1774
Query: 791 TKAGNT----KEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVKETLQKS 846
++ + HL ++ N L+ E+E + +K ++ +++
Sbjct: 1775 ANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVREL 1834
Query: 847 GVRKEFPITEAVGSDKTNRHPLECLPGLIQDKEWNEKELQKLHCAFASLPKHKPGFWSEV 906
E I + + + R C+ L E ++K L ++ L + +V
Sbjct: 1835 EGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQV 1894
Query: 907 AAA 909
A
Sbjct: 1895 EVA 1897
Score = 35.4 bits (80), Expect = 0.31
Identities = 71/373 (19%), Positives = 138/373 (36%), Gaps = 35/373 (9%)
Query: 471 IDNFLEQLRAGEKNREKTKQKQKTGRSVRDIRKSMKNDARENQTD-TAQRATTTYDFDCD 529
++ L+ R +N E +++ +++ S N EN+ AQ T +
Sbjct: 1067 LEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQ 1126
Query: 530 NLELKSNKHSESPGATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKE 589
+LK +E ++ + + L +N ++ GG L+ E+ K+E
Sbjct: 1127 IKDLKEKLEAERTTRAKME------RERADLTQDLADLNERLEEVGGSSLAQLEITKKQE 1180
Query: 590 YKMSSKKLKIGE-----RTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAIN 644
K + E T +K + ++ EL+ ++ L +Q ++++ + +
Sbjct: 1181 TKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKL-EKDKSDLQLE 1239
Query: 645 QKKAYILVTPLKSRKV-IEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTF 703
V + K E+ C Y A D V L N
Sbjct: 1240 VDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVT--------------QLANDL 1285
Query: 704 EGHKSKNKEDCDERDLLTVNRKIKISNLEKEQM-LTSDFKKNTRLLPKLKKIENQVAMSF 762
K+K + E ++ I+ L +E+ T + L K K ++ +A +
Sbjct: 1286 AAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHAL 1345
Query: 763 YKHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETE 822
K Q DL E+ E E+E+ KAE+ +T + E V K N + + E
Sbjct: 1346 QKAQRDCDLLREQYEEEQEV--KAELHRTLSKVNAEMVQWRMKYENNV----IQRTEDLE 1399
Query: 823 ESENEFYIKQKKA 835
+++ E I+ ++A
Sbjct: 1400 DAKKELAIRLQEA 1412
>gi|224586823 coiled-coil domain containing 110 isoform b [Homo
sapiens]
Length = 796
Score = 38.1 bits (87), Expect = 0.048
Identities = 81/413 (19%), Positives = 168/413 (40%), Gaps = 60/413 (14%)
Query: 477 QLRAGEKNREKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTYDFDCDNLELKSN 536
++ G+KN + K+ TG+++ D+ K R + Q D + +K
Sbjct: 310 EMHRGKKNEKNNKEIPITGKNITDL-KFHSRVPRYTLSFLDQTKHEMKDKERQPFLVKQG 368
Query: 537 K-HSESPGATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSK 595
SE+ +++N C K +++ + + ++Q I KK ++ S+
Sbjct: 369 SIISENEKTSKVNSVTEQCVAK--IQYLQNYLKESVQ------------IQKKVMELESE 414
Query: 596 KLKIGERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMA-INQKKAYILVTP 654
L + + I TT+ L ++ + + +E+ + +++ + Y
Sbjct: 415 NLNLKSKMKPLIF------TTQSLIQKVETYEKQLKNLVEEKSTIQSKLSKTEEYSKECL 468
Query: 655 LKSRKVIEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTFEGHKSKNKEDC 714
+ +K+I +YN+ G K + + I +K + +++ L K+KE
Sbjct: 469 KEFKKIIS----KYNVLQGQNKTLEEKNIQLSLEKQQMMEALDQL---------KSKEHK 515
Query: 715 DERDLLTVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYKHQSSPDLSSE 774
+ D+ VN + ++E E M K N L+ K++ + K +SS +
Sbjct: 516 TQSDMAIVNNENNRMSIEMEAM-----KTNILLIQDEKEMLEKKTHQLLKEKSSLGNELK 570
Query: 775 ESETE-KEIKRKAEVKKTK-------AGNTKEAVVHLRKSTRNTSNIPVILEPETEE--- 823
ES+ E ++K K + KT+ K+ ++L + + ++ I+E E E
Sbjct: 571 ESQLEIIQLKEKERLAKTEQETLLQIIETVKDEKLNLETTLQESTAARQIMEREIENIQT 630
Query: 824 ----SENEFY--IKQKKARPSV-KETLQKSGVRKEFPITEAVGSDKTNRHPLE 869
+E F IK K+ S+ K +L + G E +++ V KT+ L+
Sbjct: 631 YQSTAEENFLQEIKNAKSEASIYKNSLSEIGKECEM-LSKMVMETKTDNQILK 682
>gi|22749515 coiled-coil domain containing 110 isoform a [Homo
sapiens]
Length = 833
Score = 38.1 bits (87), Expect = 0.048
Identities = 81/413 (19%), Positives = 168/413 (40%), Gaps = 60/413 (14%)
Query: 477 QLRAGEKNREKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTYDFDCDNLELKSN 536
++ G+KN + K+ TG+++ D+ K R + Q D + +K
Sbjct: 347 EMHRGKKNEKNNKEIPITGKNITDL-KFHSRVPRYTLSFLDQTKHEMKDKERQPFLVKQG 405
Query: 537 K-HSESPGATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSK 595
SE+ +++N C K +++ + + ++Q I KK ++ S+
Sbjct: 406 SIISENEKTSKVNSVTEQCVAK--IQYLQNYLKESVQ------------IQKKVMELESE 451
Query: 596 KLKIGERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMA-INQKKAYILVTP 654
L + + I TT+ L ++ + + +E+ + +++ + Y
Sbjct: 452 NLNLKSKMKPLIF------TTQSLIQKVETYEKQLKNLVEEKSTIQSKLSKTEEYSKECL 505
Query: 655 LKSRKVIEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTFEGHKSKNKEDC 714
+ +K+I +YN+ G K + + I +K + +++ L K+KE
Sbjct: 506 KEFKKIIS----KYNVLQGQNKTLEEKNIQLSLEKQQMMEALDQL---------KSKEHK 552
Query: 715 DERDLLTVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYKHQSSPDLSSE 774
+ D+ VN + ++E E M K N L+ K++ + K +SS +
Sbjct: 553 TQSDMAIVNNENNRMSIEMEAM-----KTNILLIQDEKEMLEKKTHQLLKEKSSLGNELK 607
Query: 775 ESETE-KEIKRKAEVKKTK-------AGNTKEAVVHLRKSTRNTSNIPVILEPETEE--- 823
ES+ E ++K K + KT+ K+ ++L + + ++ I+E E E
Sbjct: 608 ESQLEIIQLKEKERLAKTEQETLLQIIETVKDEKLNLETTLQESTAARQIMEREIENIQT 667
Query: 824 ----SENEFY--IKQKKARPSV-KETLQKSGVRKEFPITEAVGSDKTNRHPLE 869
+E F IK K+ S+ K +L + G E +++ V KT+ L+
Sbjct: 668 YQSTAEENFLQEIKNAKSEASIYKNSLSEIGKECEM-LSKMVMETKTDNQILK 719
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 37.4 bits (85), Expect = 0.081
Identities = 79/404 (19%), Positives = 162/404 (40%), Gaps = 71/404 (17%)
Query: 595 KKLKIGERTNERI---IKSQKQETTEELDVSIDILTSREQFFSDEERKYMAINQKKAYIL 651
+++ + E+ NE++ ++ +Q +LD+ + T +Q + + Q L
Sbjct: 418 ERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQ-----L 472
Query: 652 VTPLKSRKV----------IEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLEN 701
+T L V +E+ + S T ++ F ++ +SK + L N
Sbjct: 473 ITQLSDETVACTAAAIDTAVEEEA-QVETSPETSRSSDAFTTQHALHQAQMSKEVVELNN 531
Query: 702 TF---EGHKSKNKEDCDERDLLTVNRKIKISNLEKEQM-LTSDFKKNTRLLPKLKKIENQ 757
E K ++ ++ + + I NLE E + L + ++ R L KK NQ
Sbjct: 532 ALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQ 591
Query: 758 VAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVIL 817
+S ++H+ +L + ++ +K++ ++++ K K +T+ V L + N V L
Sbjct: 592 AKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKE-STERTVSKLNQEIWMMKNQRVQL 650
Query: 818 EPETEESENEF-YIKQKKARPSVKETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGLIQ 876
+ +E +F KQKK + ++ L++ ++++ + +
Sbjct: 651 MRQMKEDAEKFRQWKQKKDKEVIQ--LKERDRKRQYELLKL------------------- 689
Query: 877 DKEWNEKELQKLHCAFASLPKHKPGFWSEVAAAVGSRSPEECQRKYMENPRGKGSQKHVT 936
E+ QK +S+ + K +E AAA R + Q+ Q+ VT
Sbjct: 690 -----ERNFQKQ----SSVLRRK----TEEAAAANKRLKDALQK-----------QREVT 725
Query: 937 -KKKPANSKGQNGKRGDADQKQTIKITAKVGTLKRKQQMREFLE 979
K+K S G+ G +I V T + K+ + + LE
Sbjct: 726 DKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLE 769
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,488,265
Number of Sequences: 37866
Number of extensions: 2083865
Number of successful extensions: 6922
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 231
Number of HSP's that attempted gapping in prelim test: 6488
Number of HSP's gapped (non-prelim): 702
length of query: 1132
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1019
effective length of database: 13,968,660
effective search space: 14234064540
effective search space used: 14234064540
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.