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Search of human proteins with 41327773
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
(1031 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 2021 0.0
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 399 e-110
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 399 e-110
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 390 e-108
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 363 e-100
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 363 e-100
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 360 5e-99
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 342 1e-93
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 311 2e-84
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 293 4e-79
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 289 1e-77
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 289 1e-77
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 277 4e-74
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 271 3e-72
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 271 3e-72
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 271 3e-72
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 268 3e-71
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 235 1e-61
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 235 1e-61
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 230 5e-60
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 218 3e-56
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 217 4e-56
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 216 1e-55
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 214 3e-55
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 210 6e-54
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 205 2e-52
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 203 6e-52
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 201 2e-51
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 198 2e-50
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 195 2e-49
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens]
Length = 1031
Score = 2021 bits (5237), Expect = 0.0
Identities = 1031/1031 (100%), Positives = 1031/1031 (100%)
Query: 1 MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRS 60
MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRS
Sbjct: 1 MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRS 60
Query: 61 RSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS 120
RSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS
Sbjct: 61 RSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS 120
Query: 121 KEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAME 180
KEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAME
Sbjct: 121 KEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAME 180
Query: 181 NIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVK 240
NIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVK
Sbjct: 181 NIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVK 240
Query: 241 KFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEE 300
KFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEE
Sbjct: 241 KFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEE 300
Query: 301 VDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGI 360
VDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGI
Sbjct: 301 VDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGI 360
Query: 361 TVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGS 420
TVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGS
Sbjct: 361 TVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGS 420
Query: 421 GKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVY 480
GKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVY
Sbjct: 421 GKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVY 480
Query: 481 GGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFE 540
GGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFE
Sbjct: 481 GGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFE 540
Query: 541 PQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVI 600
PQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVI
Sbjct: 541 PQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVI 600
Query: 601 EEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDS 660
EEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDS
Sbjct: 601 EEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDS 660
Query: 661 IINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAY 720
IINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAY
Sbjct: 661 IINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAY 720
Query: 721 TFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKF 780
TFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKF
Sbjct: 721 TFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKF 780
Query: 781 DETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPA 840
DETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPA
Sbjct: 781 DETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPA 840
Query: 841 PTAGNAEKLEIAKRLALRINAQKNLGIESQDVMQQATNAILRGGTILAPTVSAKTIAEQL 900
PTAGNAEKLEIAKRLALRINAQKNLGIESQDVMQQATNAILRGGTILAPTVSAKTIAEQL
Sbjct: 841 PTAGNAEKLEIAKRLALRINAQKNLGIESQDVMQQATNAILRGGTILAPTVSAKTIAEQL 900
Query: 901 AEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISE 960
AEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISE
Sbjct: 901 AEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISE 960
Query: 961 YSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSY 1020
YSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSY
Sbjct: 961 YSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSY 1020
Query: 1021 QPTNKGRYKVL 1031
QPTNKGRYKVL
Sbjct: 1021 QPTNKGRYKVL 1031
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 399 bits (1024), Expect = e-110
Identities = 235/603 (38%), Positives = 347/603 (57%), Gaps = 42/603 (6%)
Query: 201 EDDDDDEDD------PAEAEKEGNEMEGEELD------PLDAYMEEVKEEVKKFNMRSVK 248
ED+++D + PAE + + +D PL+A+M EV+++ + R +
Sbjct: 77 EDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEE 136
Query: 249 GGGGNEKKSGPTVTKVVTVVTTKKAV---VDSDKKKGELMENDQDAMEYSSEEEEVDLQT 305
E+K+ + + ++A + + G + E ++D +EY S+ +
Sbjct: 137 KD--KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPI---- 190
Query: 306 ALTGYQTKQRKLLEP---VDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITV 362
+K+++P +DH +I+Y PF KNFY E E+ ++ +++ R ++ + V
Sbjct: 191 ------APTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN-LRV 243
Query: 363 KGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGK 422
G P+P S+ G ++++ ++K Y +PTPIQ Q +P +SGRD+IGIAKTGSGK
Sbjct: 244 SGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGK 303
Query: 423 TIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGG 482
T AF+ PM HIMDQ+ LE G+GPIAVI+ PTREL QI ECK+F K LR V VYGG
Sbjct: 304 TAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGG 363
Query: 483 TGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQ 542
+ EQ L+ GAEI+VCTPGR+ID + + TNL+RV+Y+V DEADRMFDMGFE Q
Sbjct: 364 GSMWEQAKALQEGAEIVVCTPGRLIDHV---KKKATNLQRVSYLVFDEADRMFDMGFEYQ 420
Query: 543 VMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEE 602
V I +VRPDRQT++FSATF + +E LAR IL PI V G DV Q V ++
Sbjct: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480
Query: 603 -EKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSI 661
K+ L L + SGSV++FV K+ +A+ L +L + + LHG +DQ +R+ +
Sbjct: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
Query: 662 INDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYT 721
I+DFK +LVAT VAARGLD+ + V+NY + + HR GRTGRAG KG AYT
Sbjct: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
Query: 722 FITEDQARYAGDIIKALELSGTAVPPDL-----EKLWSDFKDQQKAEGKIIKKSSGFSGK 776
+T + +AGD+++ LE + V +L + W F+ + GK K + G G
Sbjct: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAW--FRKSRFKGGKGKKLNIGGGGL 658
Query: 777 GFK 779
G++
Sbjct: 659 GYR 661
Score = 31.6 bits (70), Expect = 4.0
Identities = 33/138 (23%), Positives = 46/138 (33%), Gaps = 10/138 (7%)
Query: 12 SASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRS 71
S + R G+ + RG R S +R + R D R R S
Sbjct: 792 SGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESSS 851
Query: 72 RSRERDRSRERRRSRSRDRR-RSRSRSRGRRSRSSSPG-NKSKKTENRSRSKEKTDGGES 129
R + R E R S R +R + GR S N+ K E + K +
Sbjct: 852 RHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKMEPKVDS----- 906
Query: 130 SKEKKKDKDDKEDEKEKD 147
K DK D + +K D
Sbjct: 907 ---SKMDKVDSKTDKTAD 921
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 399 bits (1024), Expect = e-110
Identities = 235/603 (38%), Positives = 347/603 (57%), Gaps = 42/603 (6%)
Query: 201 EDDDDDEDD------PAEAEKEGNEMEGEELD------PLDAYMEEVKEEVKKFNMRSVK 248
ED+++D + PAE + + +D PL+A+M EV+++ + R +
Sbjct: 77 EDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFMAEVEDQAARDMKRLEE 136
Query: 249 GGGGNEKKSGPTVTKVVTVVTTKKAV---VDSDKKKGELMENDQDAMEYSSEEEEVDLQT 305
E+K+ + + ++A + + G + E ++D +EY S+ +
Sbjct: 137 KD--KERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPI---- 190
Query: 306 ALTGYQTKQRKLLEP---VDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITV 362
+K+++P +DH +I+Y PF KNFY E E+ ++ +++ R ++ + V
Sbjct: 191 ------APTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN-LRV 243
Query: 363 KGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGK 422
G P+P S+ G ++++ ++K Y +PTPIQ Q +P +SGRD+IGIAKTGSGK
Sbjct: 244 SGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGK 303
Query: 423 TIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGG 482
T AF+ PM HIMDQ+ LE G+GPIAVI+ PTREL QI ECK+F K LR V VYGG
Sbjct: 304 TAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGG 363
Query: 483 TGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQ 542
+ EQ L+ GAEI+VCTPGR+ID + + TNL+RV+Y+V DEADRMFDMGFE Q
Sbjct: 364 GSMWEQAKALQEGAEIVVCTPGRLIDHV---KKKATNLQRVSYLVFDEADRMFDMGFEYQ 420
Query: 543 VMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEE 602
V I +VRPDRQT++FSATF + +E LAR IL PI V G DV Q V ++
Sbjct: 421 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 480
Query: 603 -EKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSI 661
K+ L L + SGSV++FV K+ +A+ L +L + + LHG +DQ +R+ +
Sbjct: 481 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 540
Query: 662 INDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYT 721
I+DFK +LVAT VAARGLD+ + V+NY + + HR GRTGRAG KG AYT
Sbjct: 541 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 600
Query: 722 FITEDQARYAGDIIKALELSGTAVPPDL-----EKLWSDFKDQQKAEGKIIKKSSGFSGK 776
+T + +AGD+++ LE + V +L + W F+ + GK K + G G
Sbjct: 601 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAW--FRKSRFKGGKGKKLNIGGGGL 658
Query: 777 GFK 779
G++
Sbjct: 659 GYR 661
Score = 31.6 bits (70), Expect = 4.0
Identities = 33/138 (23%), Positives = 46/138 (33%), Gaps = 10/138 (7%)
Query: 12 SASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRS 71
S + R G+ + RG R S +R + R D R R S
Sbjct: 792 SGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESSS 851
Query: 72 RSRERDRSRERRRSRSRDRR-RSRSRSRGRRSRSSSPG-NKSKKTENRSRSKEKTDGGES 129
R + R E R S R +R + GR S N+ K E + K +
Sbjct: 852 RHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKMEPKVDS----- 906
Query: 130 SKEKKKDKDDKEDEKEKD 147
K DK D + +K D
Sbjct: 907 ---SKMDKVDSKTDKTAD 921
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 390 bits (1002), Expect = e-108
Identities = 282/826 (34%), Positives = 415/826 (50%), Gaps = 100/826 (12%)
Query: 21 RSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRL-RRSRSRERDRS 79
+ R SPS + KR R RDRDR R+ S S+D++R RSRDR+R RSRSR R +S
Sbjct: 9 KDRDASPSKEERKRSRTP-DRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKS 67
Query: 80 RERRR---SRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKD 136
ER R R RD+ R R++ R + +K +K + S + K ++ KKD
Sbjct: 68 AERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKD 127
Query: 137 KDDKEDEKEKDAGNFD------QNKLEEEMRKRKERVEKWREEQR--KKAMENIGELKKE 188
++D+ +K+ A + K EEE + + + K E K+ + + E ++
Sbjct: 128 EEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRM 187
Query: 189 IEEMKQGKKWSLEDDDDDEDDPAEAEKEGN------EMEGEELDPLDAYMEEVKEEVKKF 242
+EE ++ +K + +DP E E+ E G E + + E K++ K+
Sbjct: 188 LEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKEL 247
Query: 243 NMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVD 302
+ + GG +K+ + + +K V + D + + D E +V
Sbjct: 248 HAIKERYLGGIKKR------RRTRHLNDRKFVFEWDASE----DTSIDYNPLYKERHQVQ 297
Query: 303 L-----------------QTALTGYQTKQRKLLEPVDHGKIEYEPFRK--------NFYV 337
L Q+ G ++R+ LE + + RK + +
Sbjct: 298 LLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHW 357
Query: 338 EVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTP 397
+L +M+ + +FR E IT KG P PI+SW + IL + K GY++PTP
Sbjct: 358 SQKKLDEMTDRDWRIFR-EDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTP 416
Query: 398 IQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMD----QRSLEEGEGPIAVIMTP 453
IQ QAIP + RD+IG+A+TGSGKT AFL+P+ I R E +GP A+I+ P
Sbjct: 417 IQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAP 476
Query: 454 TRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAAN 513
TRELA QI +E KF K LG+R V V GG +Q L+ G EI++ TPGR+ID+L
Sbjct: 477 TRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVL--- 533
Query: 514 SGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRI-----VDNVRPD--------------- 553
R L R TYVVLDEADRM DMGFEP V +I V N +PD
Sbjct: 534 ENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFE 593
Query: 554 ------RQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFL 607
RQTVMF+AT P A+E LAR L +P V +G VEQ+V ++ E +K
Sbjct: 594 SGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRK 653
Query: 608 KLLELLGHYQESG---SVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIIND 664
KLL +L E G +IIFV++++ D L K L + Y +LHGG Q R+ +++
Sbjct: 654 KLLAIL----EQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSN 709
Query: 665 FKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFIT 724
K G +LVAT VA RG+D++ + +VVNY + EDY+HR GRTGRAG G A TF+T
Sbjct: 710 LKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLT 769
Query: 725 EDQARYAGDIIKA-LELSGTAVPPDLEKLWSDFKDQQKAEGKIIKK 769
++ + ++ +A LE ++ PP+L ++ D Q G I+ K
Sbjct: 770 KEDSAVFYELKQAILESPVSSCPPEL----ANHPDAQHKPGTILTK 811
Score = 62.4 bits (150), Expect = 2e-09
Identities = 61/278 (21%), Positives = 120/278 (43%), Gaps = 74/278 (26%)
Query: 50 ERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGN 109
E + +D+ S S++ ++ R+ RERDR R+R+ S S+DR+R RSR R R G+
Sbjct: 4 ELADKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRG------GS 57
Query: 110 KSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEK 169
+S+ +RSRSK S E+++ ++E +KE+D D+++ ++ R+ K+R
Sbjct: 58 RSR---SRSRSK--------SAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRS 106
Query: 170 WREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLD 229
R K ++ +K+ + K D+ED+ + + + + EEL
Sbjct: 107 SLSPGRGKDFKS----RKDRDSKK-----------DEEDEHGDKKPKAQPLSLEEL---- 147
Query: 230 AYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQ 289
+ KKA +++ K L + ++
Sbjct: 148 --------------------------------------LAKKKAEEEAEAKPKFLSKAER 169
Query: 290 DAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIE 327
+A ++EV+ + + + K+RK + + +E
Sbjct: 170 EAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLE 207
Score = 33.9 bits (76), Expect = 0.81
Identities = 44/244 (18%), Positives = 89/244 (36%), Gaps = 44/244 (18%)
Query: 4 ESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSR 63
E H K+ ++ S ++ +++ ++ S++ +R + + R R
Sbjct: 129 EDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRML 188
Query: 64 DRKRLRRSRSRERDRS-----RERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRS 118
+ +R +R + ++ R +ER R R+R + + K++
Sbjct: 189 EEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELH 248
Query: 119 RSKEKTDGGESSKEKKKDKDDKEDEKEKDAG---NFDQNKLEEE---------------- 159
KE+ GG + + + +D++ E DA + D N L +E
Sbjct: 249 AIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGID 308
Query: 160 ---------------MRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDD 204
M KR+ EK +EE R + + KKE ++ + WS + D
Sbjct: 309 LKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLR-----KKEAKQRWDDRHWSQKKLD 363
Query: 205 DDED 208
+ D
Sbjct: 364 EMTD 367
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 363 bits (932), Expect = e-100
Identities = 194/430 (45%), Positives = 275/430 (63%), Gaps = 8/430 (1%)
Query: 327 EYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKG-CPKPIKSWVQCGISMKILN 385
E F KNFYVE PE+A+++ EV+ R + E ITV+G CPKP+ ++ +++
Sbjct: 126 ELPKFEKNFYVEHPEVARLTPYEVDELRRKKE-ITVRGGDVCPKPVFAFHHANFPQYVMD 184
Query: 386 SLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEG 445
L + +PTPIQ Q P +SGRD++GIA+TGSGKT+A+LLP HI Q LE G+G
Sbjct: 185 VLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDG 244
Query: 446 PIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGR 505
PI +++ PTRELA Q+ + + K L+ C+YGG QI +L+RG EI + TPGR
Sbjct: 245 PICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGR 304
Query: 506 MIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPR 565
+ID L SG+ TNLRR TY+VLDEADRM DMGFEPQ+ +IVD +RPDRQT+M+SAT+P+
Sbjct: 305 LIDFL--ESGK-TNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPK 361
Query: 566 AMEALARRILSKPIEVQVGGRSVVCS-DVEQQVIVIEEEKKFLKLLELLGHY--QESGSV 622
+ LA L ++ VG + + ++ Q V V E +K KL++L+ ++
Sbjct: 362 EVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKT 421
Query: 623 IIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARG 682
IIFV+ + D L + + R +P M +HG Q +RD ++N+F++G +L+AT VA+RG
Sbjct: 422 IIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRG 481
Query: 683 LDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSG 742
LDV+ + V+NY PN EDYVHR GRT R+ NKG AYTF T + A ++IK LE +
Sbjct: 482 LDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEAN 541
Query: 743 TAVPPDLEKL 752
A+ P L +L
Sbjct: 542 QAINPKLMQL 551
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 363 bits (932), Expect = e-100
Identities = 194/430 (45%), Positives = 275/430 (63%), Gaps = 8/430 (1%)
Query: 327 EYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKG-CPKPIKSWVQCGISMKILN 385
E F KNFYVE PE+A+++ EV+ R + E ITV+G CPKP+ ++ +++
Sbjct: 126 ELPKFEKNFYVEHPEVARLTPYEVDELRRKKE-ITVRGGDVCPKPVFAFHHANFPQYVMD 184
Query: 386 SLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEG 445
L + +PTPIQ Q P +SGRD++GIA+TGSGKT+A+LLP HI Q LE G+G
Sbjct: 185 VLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDG 244
Query: 446 PIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGR 505
PI +++ PTRELA Q+ + + K L+ C+YGG QI +L+RG EI + TPGR
Sbjct: 245 PICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGR 304
Query: 506 MIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPR 565
+ID L SG+ TNLRR TY+VLDEADRM DMGFEPQ+ +IVD +RPDRQT+M+SAT+P+
Sbjct: 305 LIDFL--ESGK-TNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPK 361
Query: 566 AMEALARRILSKPIEVQVGGRSVVCS-DVEQQVIVIEEEKKFLKLLELLGHY--QESGSV 622
+ LA L ++ VG + + ++ Q V V E +K KL++L+ ++
Sbjct: 362 EVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKT 421
Query: 623 IIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARG 682
IIFV+ + D L + + R +P M +HG Q +RD ++N+F++G +L+AT VA+RG
Sbjct: 422 IIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRG 481
Query: 683 LDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSG 742
LDV+ + V+NY PN EDYVHR GRT R+ NKG AYTF T + A ++IK LE +
Sbjct: 482 LDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEAN 541
Query: 743 TAVPPDLEKL 752
A+ P L +L
Sbjct: 542 QAINPKLMQL 551
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 360 bits (923), Expect = 5e-99
Identities = 179/433 (41%), Positives = 270/433 (62%), Gaps = 9/433 (2%)
Query: 327 EYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNS 386
E F KNFY E P+LA+ + +EV +R E ITV+G CPKP+ ++ + +++
Sbjct: 50 ELPKFEKNFYQEHPDLARRTAQEVETYRRSKE-ITVRGHNCPKPVLNFYEANFPANVMDV 108
Query: 387 LKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGP 446
+ + + +PT IQ Q P +SG D++G+A+TGSGKT+++LLP HI Q LE G+GP
Sbjct: 109 IARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGP 168
Query: 447 IAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRM 506
I +++ PTRELA Q+ + ++ + L+ C+YGG QI +L+RG EI + TPGR+
Sbjct: 169 ICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 228
Query: 507 IDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRA 566
ID L TNLRR TY+VLDEADRM DMGFEPQ+ +IVD +RPDRQT+M+SAT+P+
Sbjct: 229 IDFLECGK---TNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKE 285
Query: 567 MEALARRILSKPIEVQVGGRSVVCSDVEQQVI----VIEEEKKFLKLLELLGHYQESGSV 622
+ LA L I + +G + + Q++ +E+++K ++L+E + +E+
Sbjct: 286 VRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKEN-KT 344
Query: 623 IIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARG 682
I+FV+ + D L + + R +P M +HG Q +RD ++N+FK+G +L+AT VA+RG
Sbjct: 345 IVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRG 404
Query: 683 LDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSG 742
LDV+ + V+NY PN EDY+HR GRT R+ G AYTF T + + D+I L +
Sbjct: 405 LDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREAN 464
Query: 743 TAVPPDLEKLWSD 755
A+ P L +L D
Sbjct: 465 QAINPKLLQLVED 477
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 342 bits (877), Expect = 1e-93
Identities = 194/446 (43%), Positives = 283/446 (63%), Gaps = 18/446 (4%)
Query: 330 PFRKNFYVEVPELAKMSQEEVNVFRLEMEGITV------KGKGCPKPIKSW---VQCGIS 380
P +KNFY E + MS+ E + +R E IT + + P P ++ QC
Sbjct: 193 PIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQC--Y 250
Query: 381 MKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSL 440
+++ ++KK G++KPTPIQ+QA P ++ G DLIG+A+TG+GKT+ +L+P F H++ Q SL
Sbjct: 251 PEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSL 310
Query: 441 E-EGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEII 499
+ + P +++TPTRELALQ+ EC K+S GLR VCVYGG EQI ELK+G +II
Sbjct: 311 KGQRNRPGMLVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNRDEQIEELKKGVDII 369
Query: 500 VCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMF 559
+ TPGR+ D+ +N NL+ +TY+VLDEAD+M DMGFEPQ+M+I+ +VRPDRQTVM
Sbjct: 370 IATPGRLNDLQMSN---FVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMT 426
Query: 560 SATFPRAMEALARRILSKPIEVQVGGRSVVC-SDVEQQVIVIEEEKKFLKLLELLGHYQE 618
SAT+P ++ LA+ L +P+ V VG +V S V+Q +IV EE+K+ + L
Sbjct: 427 SATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSS 486
Query: 619 SGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSV 678
+ VI+FV ++ AD L DL+ + SLHG +Q DR+ + +FK G ++L+AT +
Sbjct: 487 TDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDL 546
Query: 679 AARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKAL 738
A+RGLDV + V N+ P + E+YVHR GRTGRAG G + T +T + R A ++I L
Sbjct: 547 ASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINIL 606
Query: 739 ELSGTAVPPDLEKLWSDFK-DQQKAE 763
E + ++P +L + FK QQK E
Sbjct: 607 ERANQSIPEELVSMAERFKAHQQKRE 632
>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
Length = 631
Score = 311 bits (797), Expect = 2e-84
Identities = 182/461 (39%), Positives = 272/461 (59%), Gaps = 14/461 (3%)
Query: 330 PFRKNFYVEVPELAKMSQEEVNVFRLEMEGITV------KGKGCPKPIKSWVQCGISMK- 382
P +KNFY+E + MS+ +V +R E IT + + PKP +
Sbjct: 173 PVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCRFKDAFQQYPD 232
Query: 383 ILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQR-SLE 441
+L S+ + G KPTPIQ+QA P I+ G DLI +A+TG+GKT+++L+P F H+ Q S E
Sbjct: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISRE 292
Query: 442 EGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVC 501
+ GP +++TPTRELAL + EC K+S GL+ +C+YGG + QI ++ +G +II+
Sbjct: 293 QRNGPGMLVLTPTRELALHVEAECSKYSYK-GLKSICIYGGRNRNGQIEDISKGVDIIIA 351
Query: 502 TPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSA 561
TPGR+ D+ NS NLR +TY+V+DEAD+M DM FEPQ+ +I+ +VRPDRQTVM SA
Sbjct: 352 TPGRLNDLQMNNS---VNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSA 408
Query: 562 TFPRAMEALARRILSKPIEVQVGGRSVVC-SDVEQQVIVIEEEKKFLKLLELLGHYQESG 620
T+P + LA L P+ V VG ++V + V+Q +IV E++K E + + +
Sbjct: 409 TWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPND 468
Query: 621 SVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAA 680
VI+FV ++ AD L D SLHG +Q D++ + DFK+G K+L+ T + +
Sbjct: 469 KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVS 528
Query: 681 RGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALEL 740
RGLD+ + V NY P + + YVHR G GR G G + T IT+ ++ AG++IK L+
Sbjct: 529 RGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDR 588
Query: 741 SGTAVPPDLEKLWSDFK-DQQKAEGKIIKKSSGFSGKGFKF 780
+ +VP DL + +K +QQK + + G K F F
Sbjct: 589 ANQSVPEDLVVMAEQYKLNQQKRHRETRSRKPGQRRKEFYF 629
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 293 bits (751), Expect = 4e-79
Identities = 173/458 (37%), Positives = 259/458 (56%), Gaps = 22/458 (4%)
Query: 341 ELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQT 400
EL +N + + + G CP I+S+ + I+ +++ Y +PTP+Q
Sbjct: 149 ELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQK 208
Query: 401 QAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ------RSLEEG-------EGPI 447
AIP I RDL+ A+TGSGKT AFLLP+ I R+++E + PI
Sbjct: 209 HAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPI 268
Query: 448 AVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMI 507
++++ PTRELA+QI +E +KFS +R VYGG I +QI +L+RG ++V TPGR++
Sbjct: 269 SLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLV 328
Query: 508 DMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIV--DNVRPD--RQTVMFSATF 563
DM+ G++ L Y+VLDEADRM DMGFEPQ+ RIV D + P R T+MFSATF
Sbjct: 329 DMM--ERGKI-GLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATF 385
Query: 564 PRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVI 623
P+ ++ LAR L + I + VG ++ Q+V+ +EE K LL+LL + +
Sbjct: 386 PKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTL 445
Query: 624 IFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGL 683
+FV+ ++ AD L L Y C S+HG Q DR+ ++ F++G +LVAT+VAARGL
Sbjct: 446 VFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGL 505
Query: 684 DVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGT 743
D+ ++ V+N+ P+ E+YVHR GRTGR GN G A +F E D++ L +
Sbjct: 506 DISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQ 565
Query: 744 AVPPDLEKLWSD--FKDQQKAEGKIIKKSSGFSGKGFK 779
VP LE + + +K + K + S GF + ++
Sbjct: 566 EVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYR 603
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 289 bits (739), Expect = 1e-77
Identities = 170/458 (37%), Positives = 259/458 (56%), Gaps = 22/458 (4%)
Query: 341 ELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQT 400
EL +N + + + G CP I+++ + I+ +++ Y +PTP+Q
Sbjct: 147 ELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQK 206
Query: 401 QAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ------RSLEEG-------EGPI 447
AIP I RDL+ A+TGSGKT AFLLP+ I ++++E + PI
Sbjct: 207 HAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPI 266
Query: 448 AVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMI 507
++++ PTRELA+QI +E +KFS +R VYGG I +QI +L+RG ++V TPGR++
Sbjct: 267 SLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLV 326
Query: 508 DMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIV--DNVRPD--RQTVMFSATF 563
DM+ G++ L Y+VLDEADRM DMGFEPQ+ RIV D + P R T+MFSATF
Sbjct: 327 DMM--ERGKI-GLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATF 383
Query: 564 PRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVI 623
P+ ++ LAR L + I + VG ++ Q+V+ +E+ K LL++LG +
Sbjct: 384 PKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTL 443
Query: 624 IFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGL 683
+FV+ ++ AD L L Y C S+HG Q DR+ ++ F++G +LVAT+VAARGL
Sbjct: 444 VFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGL 503
Query: 684 DVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGT 743
D+ ++ V+N+ P+ E+YVHR GRTGR GN G A +F E D++ L +
Sbjct: 504 DISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQ 563
Query: 744 AVPPDLEKLWSD--FKDQQKAEGKIIKKSSGFSGKGFK 779
VP LE + + +K + K + S GF + ++
Sbjct: 564 EVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYR 601
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 289 bits (739), Expect = 1e-77
Identities = 170/458 (37%), Positives = 259/458 (56%), Gaps = 22/458 (4%)
Query: 341 ELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQT 400
EL +N + + + G CP I+++ + I+ +++ Y +PTP+Q
Sbjct: 147 ELFSGGNTGINFEKYDDIPVEATGSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQK 206
Query: 401 QAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ------RSLEEG-------EGPI 447
AIP I RDL+ A+TGSGKT AFLLP+ I ++++E + PI
Sbjct: 207 HAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPI 266
Query: 448 AVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMI 507
++++ PTRELA+QI +E +KFS +R VYGG I +QI +L+RG ++V TPGR++
Sbjct: 267 SLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLV 326
Query: 508 DMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIV--DNVRPD--RQTVMFSATF 563
DM+ G++ L Y+VLDEADRM DMGFEPQ+ RIV D + P R T+MFSATF
Sbjct: 327 DMM--ERGKI-GLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATF 383
Query: 564 PRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVI 623
P+ ++ LAR L + I + VG ++ Q+V+ +E+ K LL++LG +
Sbjct: 384 PKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTL 443
Query: 624 IFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGL 683
+FV+ ++ AD L L Y C S+HG Q DR+ ++ F++G +LVAT+VAARGL
Sbjct: 444 VFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGL 503
Query: 684 DVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGT 743
D+ ++ V+N+ P+ E+YVHR GRTGR GN G A +F E D++ L +
Sbjct: 504 DISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQ 563
Query: 744 AVPPDLEKLWSD--FKDQQKAEGKIIKKSSGFSGKGFK 779
VP LE + + +K + K + S GF + ++
Sbjct: 564 EVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYR 601
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 277 bits (708), Expect = 4e-74
Identities = 177/484 (36%), Positives = 256/484 (52%), Gaps = 27/484 (5%)
Query: 290 DAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGK-----------IEYEPFRKNFYVE 338
D ++ E+ E ++A ++ K+LE V G+ I Y+ K +
Sbjct: 89 DQHQHLKEKAEARKESAKEKQLKEEEKILESVAEGRALMSVKEMAKGITYDDPIKTSWTP 148
Query: 339 VPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPI 398
+ MS+E R + I V+G G P PIKS+ + IL LKK G PTPI
Sbjct: 149 PRYVLSMSEERHERVRKKYH-ILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPI 207
Query: 399 QTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRS---LEEGEGPIAVIMTPTR 455
Q Q IP I+SGRD+IGIA TGSGKT+ F LP+ ++Q + EGP +I+ P+R
Sbjct: 208 QIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSR 267
Query: 456 ELALQITKECKKFSKTLG------LRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDM 509
ELA Q + + + L LR GG + EQ+ ++ G ++V TPGR++D+
Sbjct: 268 ELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDL 327
Query: 510 LAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEA 569
L ++ +L Y+ LDEADRM DMGFE + I + RQT++FSAT P+ ++
Sbjct: 328 LQK---KMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQN 384
Query: 570 LARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQ 629
A+ L KP+ + VG DV Q+V ++EE K + LLE L + V+IF +K+
Sbjct: 385 FAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAKMVYLLECL--QKTPPPVLIFAEKK 442
Query: 630 EHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLI 689
D + + L+ +++HGG DQ +R I F+ G +LVAT VA++GLD +
Sbjct: 443 ADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQ 502
Query: 690 LVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSG-TAVPPD 748
V+NY P E+YVHR GRTGR+GN G A TFI + +KAL L VPP
Sbjct: 503 HVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPV 562
Query: 749 LEKL 752
L+ L
Sbjct: 563 LQVL 566
Score = 32.7 bits (73), Expect = 1.8
Identities = 20/87 (22%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Query: 112 KKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNK-LEEEMRKRKERVEKW 170
K + R + + + +S E + D+DD + + DQ++ L+E+ RKE ++
Sbjct: 49 KLLQRRRKGAAEEEQQDSGSEPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEK 108
Query: 171 REEQRKKAMENI--GELKKEIEEMKQG 195
+ ++ +K +E++ G ++EM +G
Sbjct: 109 QLKEEEKILESVAEGRALMSVKEMAKG 135
Score = 31.2 bits (69), Expect = 5.3
Identities = 24/107 (22%), Positives = 42/107 (39%)
Query: 38 RRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRS 97
+R+R+ + RS + D+ LR+ R + +RRR + + + S S
Sbjct: 9 KRARTDEVPAGGSRSEAEDEDDEDYVPYVPLRQRRQLLLQKLLQRRRKGAAEEEQQDSGS 68
Query: 98 RGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEK 144
R P + + + E+ KE K+K KE+EK
Sbjct: 69 EPRGDEDDIPLGPQSNVSLLDQHQHLKEKAEARKESAKEKQLKEEEK 115
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 271 bits (692), Expect = 3e-72
Identities = 156/416 (37%), Positives = 243/416 (58%), Gaps = 14/416 (3%)
Query: 347 QEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAI 406
Q +N + + + V G P I ++ + + + N++ K GY K TP+Q +IP I
Sbjct: 263 QTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPII 322
Query: 407 MSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ----RSLEEGEGPIAVIMTPTRELALQIT 462
++GRDL+ A+TGSGKT AFLLP+ H+M +E + P +I+ PTREL QI
Sbjct: 323 LAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIY 382
Query: 463 KECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRR 522
E +KFS +R V +YGGT + I ++ +G I+ TPGR++D++ L++
Sbjct: 383 LEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK---IGLKQ 439
Query: 523 VTYVVLDEADRMFDMGFEPQVMRIVD----NVRPDRQTVMFSATFPRAMEALARRIL-SK 577
+ Y+VLDEADRM DMGF P++ +++ + RQT+MFSATFP ++ LA L S
Sbjct: 440 IKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSN 499
Query: 578 PIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLK 637
+ V VG C DV+Q V+ + + K KL+E+L + + +++ FV+ ++ AD +
Sbjct: 500 YLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMV-FVETKKKADFIAT 558
Query: 638 DLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCP 697
L + S+HG +Q +R+ + DF+ G C +LVATSVAARGLD++++ V+N+ P
Sbjct: 559 FLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLP 618
Query: 698 NHYEDYVHRAGRTGRAGNKGYAYTFI-TEDQARYAGDIIKALELSGTAVPPDLEKL 752
+ ++YVHR GRTGR GN G A +F E A ++K L + VP LE++
Sbjct: 619 STIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEI 674
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 271 bits (692), Expect = 3e-72
Identities = 156/416 (37%), Positives = 243/416 (58%), Gaps = 14/416 (3%)
Query: 347 QEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAI 406
Q +N + + + V G P I ++ + + + N++ K GY K TP+Q +IP I
Sbjct: 263 QTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPII 322
Query: 407 MSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ----RSLEEGEGPIAVIMTPTRELALQIT 462
++GRDL+ A+TGSGKT AFLLP+ H+M +E + P +I+ PTREL QI
Sbjct: 323 LAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIY 382
Query: 463 KECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRR 522
E +KFS +R V +YGGT + I ++ +G I+ TPGR++D++ L++
Sbjct: 383 LEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK---IGLKQ 439
Query: 523 VTYVVLDEADRMFDMGFEPQVMRIVD----NVRPDRQTVMFSATFPRAMEALARRIL-SK 577
+ Y+VLDEADRM DMGF P++ +++ + RQT+MFSATFP ++ LA L S
Sbjct: 440 IKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSN 499
Query: 578 PIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLK 637
+ V VG C DV+Q V+ + + K KL+E+L + + +++ FV+ ++ AD +
Sbjct: 500 YLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMV-FVETKKKADFIAT 558
Query: 638 DLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCP 697
L + S+HG +Q +R+ + DF+ G C +LVATSVAARGLD++++ V+N+ P
Sbjct: 559 FLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLP 618
Query: 698 NHYEDYVHRAGRTGRAGNKGYAYTFI-TEDQARYAGDIIKALELSGTAVPPDLEKL 752
+ ++YVHR GRTGR GN G A +F E A ++K L + VP LE++
Sbjct: 619 STIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEI 674
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 271 bits (692), Expect = 3e-72
Identities = 156/416 (37%), Positives = 243/416 (58%), Gaps = 14/416 (3%)
Query: 347 QEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAI 406
Q +N + + + V G P I ++ + + + N++ K GY K TP+Q +IP I
Sbjct: 229 QTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPII 288
Query: 407 MSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ----RSLEEGEGPIAVIMTPTRELALQIT 462
++GRDL+ A+TGSGKT AFLLP+ H+M +E + P +I+ PTREL QI
Sbjct: 289 LAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIY 348
Query: 463 KECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRR 522
E +KFS +R V +YGGT + I ++ +G I+ TPGR++D++ L++
Sbjct: 349 LEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK---IGLKQ 405
Query: 523 VTYVVLDEADRMFDMGFEPQVMRIVD----NVRPDRQTVMFSATFPRAMEALARRIL-SK 577
+ Y+VLDEADRM DMGF P++ +++ + RQT+MFSATFP ++ LA L S
Sbjct: 406 IKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSN 465
Query: 578 PIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLK 637
+ V VG C DV+Q V+ + + K KL+E+L + + +++ FV+ ++ AD +
Sbjct: 466 YLFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMV-FVETKKKADFIAT 524
Query: 638 DLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCP 697
L + S+HG +Q +R+ + DF+ G C +LVATSVAARGLD++++ V+N+ P
Sbjct: 525 FLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLP 584
Query: 698 NHYEDYVHRAGRTGRAGNKGYAYTFI-TEDQARYAGDIIKALELSGTAVPPDLEKL 752
+ ++YVHR GRTGR GN G A +F E A ++K L + VP LE++
Sbjct: 585 STIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLEEI 640
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 268 bits (684), Expect = 3e-71
Identities = 156/441 (35%), Positives = 258/441 (58%), Gaps = 13/441 (2%)
Query: 313 KQRKLLEPVDHGKIEYEPFRKNF-YVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPI 371
++ KL P P ++ Y E P + + ++++ + ++ GI V+G+ +PI
Sbjct: 144 EKSKLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQL-GILVQGQEVTRPI 202
Query: 372 KSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMF 431
+ C + + ++LKK GYE PTPIQ Q IP + GRD++ A TGSGKT AFLLP+
Sbjct: 203 IDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVI 262
Query: 432 RHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLG-LRVVCVYGGTGISEQIA 490
R+L E + P A+I+TPTRELA+QI ++ K+ L ++ V + GG + Q+
Sbjct: 263 -----MRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLY 317
Query: 491 ELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNV 550
L++ ++I+ TPGR++D++ +S L V VV+DEAD M MGF+ QV+ I++N+
Sbjct: 318 RLQQHVKVIIATPGRLLDIIKQSS---VELCGVKIVVVDEADTMLKMGFQQQVLDILENI 374
Query: 551 RPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLL 610
D QT++ SAT P ++E LA ++L P+ + G +++ C++V Q ++ +E+ K KL
Sbjct: 375 PNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLF 434
Query: 611 ELLGHYQE-SGSVIIFVDKQEHADGLLKDLMRAS-YPCMSLHGGIDQYDRDSIINDFKNG 668
E+L + V++FVD + AD L + + + + +S+H Q +R +I+ G
Sbjct: 435 EILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEG 494
Query: 669 TCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQA 728
+++V+T V RGLD+ + LVVN+ P+ ++YVH+ GR GR G G A TFI +
Sbjct: 495 DYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSK 554
Query: 729 RYAGDIIKALELSGTAVPPDL 749
R DI K ++ +G+ +PP L
Sbjct: 555 RLFWDIAKRVKPTGSILPPQL 575
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 235 bits (600), Expect = 1e-61
Identities = 133/371 (35%), Positives = 204/371 (54%), Gaps = 7/371 (1%)
Query: 378 GISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ 437
G+S + + K GY+ PTPIQ + IP I+ G+D++ +A+TGSGKT FLLPMF +
Sbjct: 102 GLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERL--- 158
Query: 438 RSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAE 497
++ G A+I++PTRELALQ K K+ K GL+ + GG + +Q A L +
Sbjct: 159 KTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPD 218
Query: 498 IIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTV 557
II+ TPGR++ + S L+ V YVV DEADR+F+MGF Q+ I+ + QTV
Sbjct: 219 IIIATPGRLVHVAVEMS---LKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTV 275
Query: 558 MFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHY- 616
+FSAT P+ + AR L++P+ +++ + + ++ ++ E+ K LL LL +
Sbjct: 276 LFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVV 335
Query: 617 QESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVAT 676
+ ++FV + HA+ L + L C ++ +D R + F G C L+ T
Sbjct: 336 RPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVT 395
Query: 677 SVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIK 736
+AARGLD+ L V+NYS P + ++HR GR RAG G AY+ + D+ Y D+
Sbjct: 396 DLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDLHL 455
Query: 737 ALELSGTAVPP 747
L S T P
Sbjct: 456 FLGRSLTLARP 466
Score = 40.4 bits (93), Expect = 0.009
Identities = 49/239 (20%), Positives = 95/239 (39%), Gaps = 22/239 (9%)
Query: 6 RHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDR 65
++YR R A+ + SR R+KR DR++ +R + ++ R ++ + R
Sbjct: 567 KNYRSR-ATIFEINASSRDLCSQVMRAKRQKDRKAIARFQQGQQGRQEQQEGPVGPAPSR 625
Query: 66 KRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE--- 122
L+ ++ ++ E S + S R R+ + G K ++ E R R +E
Sbjct: 626 PALQE---KQPEKEEEEEAGESVEDIFSEVVGRKRQRSGPNRGAKRRREEARQRDQEFYI 682
Query: 123 ------------KTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEM-RKRKERVEK 169
+ GE +++ D +A N + + + + RK+K V +
Sbjct: 683 PYRPKDFDSERGLSISGEGGAFEQQAAGAVLDLMGDEAQNLTRGRQQLKWDRKKKRFVGQ 742
Query: 170 WREEQRKKAMENIGELKKEIEEMKQGKKWSLED--DDDDEDDPAEAEKEGNEMEGEELD 226
+E +KK G + +KW + DD D D+ +++ G E G + D
Sbjct: 743 SGQEDKKKIKTESGRYISSSYKRDLYQKWKQKQKIDDRDSDEEGASDRRGPERRGGKRD 801
Score = 32.7 bits (73), Expect = 1.8
Identities = 23/105 (21%), Positives = 44/105 (41%), Gaps = 1/105 (0%)
Query: 20 SRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRS 79
+R R + D++ KR + + + + E R R +K ++ + +RD
Sbjct: 724 TRGRQQLKWDRKKKRFVGQSGQEDKKKIKTESGRYISSSYKRDLYQKWKQKQKIDDRDSD 783
Query: 80 RERRRSRSRDRRRSRSRSRGR-RSRSSSPGNKSKKTENRSRSKEK 123
E R RR R RG+ SR +PG + + ++K++
Sbjct: 784 EEGASDRRGPERRGGKRDRGQGASRPHAPGTPAGRVRPELKTKQQ 828
Score = 31.6 bits (70), Expect = 4.0
Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 12/95 (12%)
Query: 33 KRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRE--------RRR 84
+RG +RR RDR + R + R R + ++ ++R R+++ ++
Sbjct: 790 RRGPERRGGKRDRGQGASRPHAPGTPAGRVRPELKTKQQILKQRRRAQKLHFLQRGGLKQ 849
Query: 85 SRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSR 119
+R+RRR + +G R G +SKK + R R
Sbjct: 850 LSARNRRRVQELQQGAFGR----GARSKKGKMRKR 880
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 235 bits (600), Expect = 1e-61
Identities = 133/371 (35%), Positives = 204/371 (54%), Gaps = 7/371 (1%)
Query: 378 GISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ 437
G+S + + K GY+ PTPIQ + IP I+ G+D++ +A+TGSGKT FLLPMF +
Sbjct: 102 GLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERL--- 158
Query: 438 RSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAE 497
++ G A+I++PTRELALQ K K+ K GL+ + GG + +Q A L +
Sbjct: 159 KTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPD 218
Query: 498 IIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTV 557
II+ TPGR++ + S L+ V YVV DEADR+F+MGF Q+ I+ + QTV
Sbjct: 219 IIIATPGRLVHVAVEMS---LKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTV 275
Query: 558 MFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHY- 616
+FSAT P+ + AR L++P+ +++ + + ++ ++ E+ K LL LL +
Sbjct: 276 LFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVV 335
Query: 617 QESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVAT 676
+ ++FV + HA+ L + L C ++ +D R + F G C L+ T
Sbjct: 336 RPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVT 395
Query: 677 SVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIK 736
+AARGLD+ L V+NYS P + ++HR GR RAG G AY+ + D+ Y D+
Sbjct: 396 DLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDLHL 455
Query: 737 ALELSGTAVPP 747
L S T P
Sbjct: 456 FLGRSLTLARP 466
Score = 40.4 bits (93), Expect = 0.009
Identities = 49/239 (20%), Positives = 95/239 (39%), Gaps = 22/239 (9%)
Query: 6 RHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDR 65
++YR R A+ + SR R+KR DR++ +R + ++ R ++ + R
Sbjct: 567 KNYRSR-ATIFEINASSRDLCSQVMRAKRQKDRKAIARFQQGQQGRQEQQEGPVGPAPSR 625
Query: 66 KRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE--- 122
L+ ++ ++ E S + S R R+ + G K ++ E R R +E
Sbjct: 626 PALQE---KQPEKEEEEEAGESVEDIFSEVVGRKRQRSGPNRGAKRRREEARQRDQEFYI 682
Query: 123 ------------KTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEM-RKRKERVEK 169
+ GE +++ D +A N + + + + RK+K V +
Sbjct: 683 PYRPKDFDSERGLSISGEGGAFEQQAAGAVLDLMGDEAQNLTRGRQQLKWDRKKKRFVGQ 742
Query: 170 WREEQRKKAMENIGELKKEIEEMKQGKKWSLED--DDDDEDDPAEAEKEGNEMEGEELD 226
+E +KK G + +KW + DD D D+ +++ G E G + D
Sbjct: 743 SGQEDKKKIKTESGRYISSSYKRDLYQKWKQKQKIDDRDSDEEGASDRRGPERRGGKRD 801
Score = 32.7 bits (73), Expect = 1.8
Identities = 35/137 (25%), Positives = 53/137 (38%), Gaps = 9/137 (6%)
Query: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
G+E + K + R S S R K+ ++ DD RD D R +RR
Sbjct: 744 GQEDKKKIKTESGRYISSSYKRDLYQKWKQKQKIDD-----RDSDEEGASDRRGPERRGG 798
Query: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRRR-SRSRSRGRRSRSSSPGN-KSKKTENRSR 119
RDR + SR R R + +++ + R R ++ G K NR R
Sbjct: 799 KRDRGQAGASRPHAPGTPAGRVRPELKTKQQILKQRRRAQKLHFLQRGGLKQLSARNRRR 858
Query: 120 SKEKTDG--GESSKEKK 134
+E G G ++ KK
Sbjct: 859 VQELQQGAFGRGARSKK 875
Score = 32.3 bits (72), Expect = 2.4
Identities = 23/106 (21%), Positives = 44/106 (41%), Gaps = 2/106 (1%)
Query: 20 SRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRS 79
+R R + D++ KR + + + + E R R +K ++ + +RD
Sbjct: 724 TRGRQQLKWDRKKKRFVGQSGQEDKKKIKTESGRYISSSYKRDLYQKWKQKQKIDDRDSD 783
Query: 80 RERRRSRSRDRRRSRSRSRGR--RSRSSSPGNKSKKTENRSRSKEK 123
E R RR R RG+ SR +PG + + ++K++
Sbjct: 784 EEGASDRRGPERRGGKRDRGQAGASRPHAPGTPAGRVRPELKTKQQ 829
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 230 bits (587), Expect = 5e-60
Identities = 146/447 (32%), Positives = 235/447 (52%), Gaps = 27/447 (6%)
Query: 372 KSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMF 431
K++ G++ + + + G+ KPT IQ +AIP + GRD+IG+A+TGSGKT AF LP+
Sbjct: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
Query: 432 RHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAE 491
+ LE + A+++TPTRELA QI+++ + ++G++ + GG Q
Sbjct: 84 NAL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLA 138
Query: 492 LKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVR 551
L + II+ TPGR+ID L G NLR + Y+V+DEADR+ +M FE +V +I+ +
Sbjct: 139 LAKKPHIIIATPGRLIDHLENTKG--FNLRALKYLVMDEADRILNMDFETEVDKILKVIP 196
Query: 552 PDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLE 611
DR+T +FSAT + ++ L R L P++ V + ++Q I I + K L+
Sbjct: 197 RDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKDTYLVY 256
Query: 612 LLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCK 671
+L S +IF + L + + LHG + Q R +N FK
Sbjct: 257 ILNELA-GNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARS 315
Query: 672 LLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYA 731
+L+AT VA+RGLD+ H+ +VVN+ P H +DY+HR GRT RAG G A TF+T+ Y
Sbjct: 316 ILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ----YD 371
Query: 732 GDIIKALE-LSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANE 790
++ + +E L G +P F Q + ++ + + +F E E
Sbjct: 372 VELFQRIEHLIGKKLP--------GFPTQDDEVMMLTERVA----EAQRFARMELREHGE 419
Query: 791 RKKLQKAALGLQDSDDEDAAVDIDEQI 817
+KK + G D+DD + A+ + ++
Sbjct: 420 KKKRSREDAG--DNDDTEGAIGVRNKV 444
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 218 bits (554), Expect = 3e-56
Identities = 141/480 (29%), Positives = 250/480 (52%), Gaps = 30/480 (6%)
Query: 374 WVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRH 433
+ + G+S ++ ++ G ++PTP+Q IPAI+ GRD +G AKTGSGKT AF+LP+
Sbjct: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPIL-- 61
Query: 434 IMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELK 493
Q+ E+ G +++TPTRELA QI ++ + K LGL+ + GG + Q EL
Sbjct: 62 ---QKLSEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELS 118
Query: 494 RGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMG---FEPQVMRIVDNV 550
R +++ TPGR+ D L S +++++ ++V+DEADR+ + G F + I+ V
Sbjct: 119 RKPHVVIATPGRLADHL--RSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAV 176
Query: 551 RPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLL 610
RQT++FSAT + L ++P + ++Q+ +++ E+ K L+
Sbjct: 177 PARRQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLV 236
Query: 611 ELLGHYQ---ESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKN 667
L+ +Q E S+IIF + + L L + S+P ++LH + Q +R + + FK+
Sbjct: 237 HLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKS 296
Query: 668 GTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQ 727
++L+AT VA+RGLD+ + +V+N++ P + Y+HR GRT RAG +G A T +T+
Sbjct: 297 SIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQ-- 354
Query: 728 ARYAGDIIKALELSGTAVPPDLEKLWSDFKD--QQKAEGKIIKKSSGFSGKGFKFDETEQ 785
Y ++ A+E + LE+ + + Q + ++++ + FDE ++
Sbjct: 355 --YDIHLVHAIE---EQIKKKLEEFSVEEAEVLQILTQVNVVRRECEIKLEAAHFDEKKE 409
Query: 786 ALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGN 845
N+RK+L + + D D ++ + +R K+ A AG+
Sbjct: 410 --INKRKQL------ILEGKDPDLEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGH 461
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 217 bits (553), Expect = 4e-56
Identities = 158/527 (29%), Positives = 268/527 (50%), Gaps = 26/527 (4%)
Query: 252 GNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQ 311
GN+K +V V T + + +KK+ L E ++ + + ++ + G
Sbjct: 50 GNKK----SVPGVCGASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGAT 105
Query: 312 TKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPI 371
+ +E KIE + ++ + +L + +E++N R + + I V+G P PI
Sbjct: 106 IQWMSSVE----AKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHK-IHVQGTDLPDPI 160
Query: 372 KSWVQCG----ISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFL 427
++ Q I+ ++L ++ G++ PTPIQ QAIP ++ GR+L+ A TGSGKT+AF
Sbjct: 161 ATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFS 220
Query: 428 LPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISE 487
+P I+ Q +G A+I++PTRELA QI +E K S+ G R+ ++ ++
Sbjct: 221 IP----ILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAK 276
Query: 488 QIA-ELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFD---MGFEPQV 543
+ + + +I+V TP R+I +L + + +L V ++V+DE+D++F+ GF Q+
Sbjct: 277 KFGPKSSKKFDILVTTPNRLIYLLKQDPPGI-DLASVEWLVVDESDKLFEDGKTGFRDQL 335
Query: 544 MRIVDNVRPDR-QTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEE 602
I + + MFSATF +E + L I V +G R+ VEQ+++ +
Sbjct: 336 ASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGS 395
Query: 603 EKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSII 662
E L + L + V++FV E A L +L+ +H Q RD+ +
Sbjct: 396 ETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTV 455
Query: 663 NDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTF 722
+ F+ G +L+ T++ ARG+D K + LV+NY P +Y+HR GRTGRAGNKG A TF
Sbjct: 456 HSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITF 515
Query: 723 ITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKK 769
TED + ++ +G VP ++ Q+K K+IKK
Sbjct: 516 FTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLLSKQKK---KMIKK 559
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
Length = 491
Score = 216 bits (549), Expect = 1e-55
Identities = 146/454 (32%), Positives = 241/454 (53%), Gaps = 18/454 (3%)
Query: 325 KIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCG----IS 380
KIE + ++ + +L + +E++N R + + I V+G P PI ++ Q I+
Sbjct: 7 KIEDKKVQRESKLTSGKLENLRKEKINFLRNKHK-IHVQGTDLPDPIATFQQLDQEYKIN 65
Query: 381 MKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSL 440
++L ++ G++ PTPIQ QAIP ++ GR+L+ A TGSGKT+AF +P I+ Q
Sbjct: 66 SRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP----ILMQLKQ 121
Query: 441 EEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIA-ELKRGAEII 499
+G A+I++PTRELA QI +E K S+ G R+ ++ +++ + + +I+
Sbjct: 122 PANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDIL 181
Query: 500 VCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFD---MGFEPQVMRIVDNVRPDR-Q 555
V TP R+I +L + + +L V ++V+DE+D++F+ GF Q+ I + +
Sbjct: 182 VTTPNRLIYLLKQDPPGI-DLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 240
Query: 556 TVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGH 615
MFSATF +E + L I V +G R+ VEQ+++ + E L + L
Sbjct: 241 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 300
Query: 616 YQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVA 675
+ V++FV E A L +L+ +H Q RD+ ++ F+ G +L+
Sbjct: 301 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 360
Query: 676 TSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDII 735
T++ ARG+D K + LV+NY P +Y+HR GRTGRAGNKG A TF TED +
Sbjct: 361 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 420
Query: 736 KALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKK 769
++ +G VP ++ Q+K K+IKK
Sbjct: 421 NVIQQAGCPVPEYIKGFQKLLSKQKK---KMIKK 451
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 214 bits (545), Expect = 3e-55
Identities = 123/358 (34%), Positives = 201/358 (56%), Gaps = 10/358 (2%)
Query: 378 GISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ 437
G+ +L + +G+EKP+ IQ +AI I+ GRD+I +++G+GKT F + + + + Q
Sbjct: 44 GLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQ 103
Query: 438 RSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAE 497
+ E + A+I+ PTRELA+QI K + ++ GGT + E I +L G
Sbjct: 104 --VRETQ---ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH 158
Query: 498 IIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTV 557
++ TPGR+ DM+ S R R + +VLDEAD M + GF+ Q+ + + P Q V
Sbjct: 159 VVAGTPGRVFDMIRRRSLRT---RAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVV 215
Query: 558 MFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIE-EEKKFLKLLELLGHY 616
+ SAT P + + + ++ PI + V + ++Q + +E EE KF L +L
Sbjct: 216 LISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTL 275
Query: 617 QESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVAT 676
+ +VI F + + D L + + A++ S+HG + Q +R+SI+ +F++G ++L++T
Sbjct: 276 TITQAVI-FCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIST 334
Query: 677 SVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDI 734
V ARGLDV + L++NY PN+ E Y+HR GR+GR G KG A F+ D R DI
Sbjct: 335 DVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 210 bits (534), Expect = 6e-54
Identities = 165/592 (27%), Positives = 279/592 (47%), Gaps = 69/592 (11%)
Query: 254 EKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQ--------- 304
+K++ T+ + + V K+ D + K G+L E +++A E S +E+ DLQ
Sbjct: 110 KKRAATTLDEKIEKVRKKRKTEDKEAKSGKL-EKEKEAKEGSEPKEQEDLQENDEEGSED 168
Query: 305 -TALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAK-MSQEEVNVFRLEMEGITV 362
+ T Y + +L D K++ +K E + SQ + N+
Sbjct: 169 EASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDENL---------- 218
Query: 363 KGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGK 422
S+ +S +L ++ G+++PTPIQ IP + G+D+ A TG+GK
Sbjct: 219 ----------SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGK 268
Query: 423 TIAFLLPMFRHIMDQRSLEEGEGPIA--VIMTPTRELALQITKECKKFSKTLGLRVVCVY 480
T AF LP+ ++ + + P+ +++ PTREL +Q+ ++ ++ +
Sbjct: 269 TAAFALPVLERLI----YKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAV 324
Query: 481 GGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFE 540
GG + Q A L+ +I++ TPGR+ID L ++ +L + ++LDEADRM D FE
Sbjct: 325 GGLDVKSQEAALRAAPDILIATPGRLIDHL--HNCPSFHLSSIEVLILDEADRMLDEYFE 382
Query: 541 PQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVI 600
Q+ I+ RQT++FSAT ++ LA L P+ + V + V + Q+ I I
Sbjct: 383 EQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRI 442
Query: 601 ----EEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQY 656
E +++ + L + + + KQ H +L LM LHG + Q
Sbjct: 443 RPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVG--ELHGNLSQT 500
Query: 657 DRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNK 716
R + FK+ +LVAT VAARGLD++ + V+N++ PN + YVHR GRT RAG
Sbjct: 501 QRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRA 560
Query: 717 GYAYTFITEDQARYAGDIIKALE--LSGTAVPPD--------LEKLWSDF---------- 756
G + + + ED+ + +I+KA + + +P D +EK+ D
Sbjct: 561 GRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEE 620
Query: 757 KDQQKAEGKI-IKKSSGFSGKGFKFDETEQA--LANERKKLQKAALGLQDSD 805
K+ Q++E +I K GK E E++ E +K +K A LQ+ D
Sbjct: 621 KEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERKKEKIAKALQEFD 672
Score = 31.6 bits (70), Expect = 4.0
Identities = 29/113 (25%), Positives = 58/113 (51%), Gaps = 15/113 (13%)
Query: 121 KEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRK------ERVEKWREEQ 174
++K G S + D E E D G++ + +++K++ E++EK R+++
Sbjct: 70 RQKALGKNRSADFNPDFVFTEKEGTYD-GSWALADVMSQLKKKRAATTLDEKIEKVRKKR 128
Query: 175 RKKAME-NIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELD 226
+ + E G+L+KE +E K+G + +++D E ++EG+E E E D
Sbjct: 129 KTEDKEAKSGKLEKE-KEAKEG------SEPKEQEDLQENDEEGSEDEASETD 174
Score = 31.6 bits (70), Expect = 4.0
Identities = 21/102 (20%), Positives = 52/102 (50%), Gaps = 8/102 (7%)
Query: 80 RERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDD 139
+++R + + D + + R + + +K K+ + KE +G E KE++ +++
Sbjct: 109 KKKRAATTLDEKIEKVRKKRKTE------DKEAKSGKLEKEKEAKEGSE-PKEQEDLQEN 161
Query: 140 KEDEKEKDAGNFDQNKLEEEMRKRKERVE-KWREEQRKKAME 180
E+ E +A D + +E + + + ++ K R++++KK E
Sbjct: 162 DEEGSEDEASETDYSSADENILTKADTLKVKDRKKKKKKGQE 203
Score = 30.4 bits (67), Expect = 9.0
Identities = 46/218 (21%), Positives = 88/218 (40%), Gaps = 31/218 (14%)
Query: 6 RHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERS------------R 53
+HY R R+G RS S G+D R ++ + + +
Sbjct: 545 KHYVHRVGRTARAGRAGRSVSLV------GEDERKMLKEIVKAAKAPVKARILPQDVILK 598
Query: 54 SRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKK 113
RDK +D + + + E+ E ++S ++ R +G+ + P +
Sbjct: 599 FRDKIEKMEKDVYAVLQLEAEEK----EMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQ 654
Query: 114 TENRSRSKEKT-----DGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRK--ER 166
T+ R KEK + + + KKK K +D K+K ++ E ++ + ER
Sbjct: 655 TKEE-RKKEKIAKALQEFDLALRGKKKRKKFMKDAKKKGEMTAEERSQFEILKAQMFAER 713
Query: 167 VEKW-REEQRKKAMENIGELKKEIEEMKQGKKWSLEDD 203
+ K R +R +AM ++ ++ KQGKK +++
Sbjct: 714 LAKRNRRAKRARAMPEEEPVRGPAKKQKQGKKSVFDEE 751
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 205 bits (521), Expect = 2e-52
Identities = 117/374 (31%), Positives = 206/374 (55%), Gaps = 11/374 (2%)
Query: 379 ISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQR 438
+ ++L + + G+EKP+PIQ ++IP +SGRD++ AK G+GK+ A+L+P+ + ++
Sbjct: 103 LKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKK 162
Query: 439 SLEEGEGPIAVIMTPTRELALQITKECKKFSKTLG-LRVVCVYGGTGISEQIAELKRGAE 497
+ A+++ PTRELALQ+++ C + SK +G +V+ GGT + + I L
Sbjct: 163 DNIQ-----AMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 217
Query: 498 IIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTV 557
+++ TPGR++D++ +V + V +VLDEAD++ F + I+ + +RQ +
Sbjct: 218 VVIATPGRILDLIKKGVAKVDH---VQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQIL 274
Query: 558 MFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQ 617
++SATFP +++ L KP E+ + + V Q + E +K L L Q
Sbjct: 275 LYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVTERQKVHCLNTLFSRLQ 333
Query: 618 ESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATS 677
+ S IIF + + + L K + + Y C +H + Q R+ + +DF+NG C+ LV T
Sbjct: 334 INQS-IIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 392
Query: 678 VAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKA 737
+ RG+D++ + +V+N+ P E Y+HR GR+GR G+ G A IT D I +
Sbjct: 393 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQ 452
Query: 738 LELSGTAVPPDLEK 751
L +P +++K
Sbjct: 453 LGTEIKPIPSNIDK 466
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 203 bits (517), Expect = 6e-52
Identities = 118/366 (32%), Positives = 197/366 (53%), Gaps = 11/366 (3%)
Query: 371 IKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPM 430
+ S+ +S +L + +G+EKP+ IQ +AI + G D+I A++G+GKT F + +
Sbjct: 31 VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90
Query: 431 FRHI-MDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQI 489
+ I +D ++ + A+++ PTRELA QI K +G GGT + ++
Sbjct: 91 LQQIELDLKATQ------ALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEV 144
Query: 490 AELKRGA-EIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVD 548
+L+ A IIV TPGR+ DML + R + + + VLDEAD M GF+ Q+ I
Sbjct: 145 QKLQMEAPHIIVGTPGRVFDML---NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQ 201
Query: 549 NVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLK 608
+ + Q V+ SAT P + + ++ + PI + V + + Q I +E E+ L
Sbjct: 202 KLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLD 261
Query: 609 LLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNG 668
L L +IF++ + D L + + + ++HG +DQ +RD I+ +F++G
Sbjct: 262 TLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSG 321
Query: 669 TCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQA 728
+ ++L+ T + ARG+DV+ + LV+NY P + E+Y+HR GR GR G KG A +TE+
Sbjct: 322 SSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDK 381
Query: 729 RYAGDI 734
R DI
Sbjct: 382 RTLRDI 387
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 201 bits (512), Expect = 2e-51
Identities = 119/353 (33%), Positives = 191/353 (54%), Gaps = 9/353 (2%)
Query: 383 ILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEE 442
+L + +G+EKP+ IQ +AI + G D+I A++G+GKT F + I+ Q +E
Sbjct: 44 LLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAIS----ILQQLEIEF 99
Query: 443 GEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGA-EIIVC 501
E A+++ PTRELA QI K +G GGT + ++ +L+ A I+V
Sbjct: 100 KETQ-ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVG 158
Query: 502 TPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSA 561
TPGR+ DML + R + + + VLDEAD M GF+ Q+ I + Q V+ SA
Sbjct: 159 TPGRVFDML---NRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSA 215
Query: 562 TFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGS 621
T P + + ++ + PI + V + ++Q I +E E+ L L L
Sbjct: 216 TMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQ 275
Query: 622 VIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAAR 681
+IF++ + D L + + + +LHG +DQ +RD I+ +F++G+ ++L+ T + AR
Sbjct: 276 AVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLAR 335
Query: 682 GLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDI 734
G+DV+ + LV+NY P + E+Y+HR GR GR G KG A F+TE+ R DI
Sbjct: 336 GIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDI 388
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 198 bits (504), Expect = 2e-50
Identities = 166/578 (28%), Positives = 274/578 (47%), Gaps = 65/578 (11%)
Query: 155 KLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAE 214
K E +RK+ E EK + + K E E + + KQ KK + + D ++
Sbjct: 18 KKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKA 77
Query: 215 KEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAV 274
K+ E ++ P + + KE ++K KVV+ TKK
Sbjct: 78 KKKEEPSQNDISPKTKSLRKKKEPIEK---------------------KVVSS-KTKKVT 115
Query: 275 VDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKN 334
+ + + E+ D + +E+E++ +T + K KL H + + P
Sbjct: 116 KNEEPSEEEI---DAPKPKKMKKEKEMNGET-----REKSPKLKNGFPHPEPDCNP---- 163
Query: 335 FYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEK 394
++ + EE N +E E + +G ++ IS + + LK G
Sbjct: 164 --------SEAASEESNS-EIEQEIPVEQKEG------AFSNFPISEETIKLLKGRGVTF 208
Query: 395 PTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ-RSLEEGEGPIAVIMTP 453
PIQ + + SG+DLI A+TG+GKT +F +P+ + + + + G P +++ P
Sbjct: 209 LFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAP 268
Query: 454 TRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAAN 513
TRELA Q++K+ +K L V C YGGT Q ++ G +I+V TPGR+ D +
Sbjct: 269 TRELANQVSKDFSDITKKLS--VACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHI--Q 324
Query: 514 SGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVD-----NVRPDRQTVMFSATFPRAME 568
+G++ +L ++ +VVLDE D+M DMGF QV I+ + + QT++FSAT P +
Sbjct: 325 NGKL-DLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVF 383
Query: 569 ALARRILSKPIE-VQVGGRSV--VCSDVEQQVIVIEEEKKFLKLLELLGHYQ-ESGSVII 624
+A++ + E V + G+ VE I ++ + +++ Y G II
Sbjct: 384 NVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTII 443
Query: 625 FVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLD 684
F + ++ A L ++ SLHG I Q R+ + F+NG+ +LVAT+VAARGLD
Sbjct: 444 FCETKKEAQELSQN-SAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLD 502
Query: 685 VKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTF 722
+ + LV+ S P E Y+HR+GRTGRAG G F
Sbjct: 503 IPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICF 540
Score = 37.4 bits (85), Expect = 0.073
Identities = 34/177 (19%), Positives = 77/177 (43%), Gaps = 5/177 (2%)
Query: 67 RLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS-KEKTD 125
+LR E D + ++ + + + + + ++ + + +++ K+K +
Sbjct: 4 KLRSDAGLESDTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAE 63
Query: 126 GGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQR-KKAMENIGE 184
E K K K +KE+ + N D + + +RK+KE +EK + KK +N
Sbjct: 64 PSEVDMNSPKSK--KAKKKEEPSQN-DISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEP 120
Query: 185 LKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKK 241
++EI+ K K ++ + + + + K G + +P +A EE E+++
Sbjct: 121 SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQ 177
Score = 35.0 bits (79), Expect = 0.36
Identities = 31/171 (18%), Positives = 76/171 (44%), Gaps = 12/171 (7%)
Query: 59 RSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRS 118
R ++ ++++ + +S + + E + ++ + ++ +SP +K K
Sbjct: 24 RKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKAK----- 78
Query: 119 RSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKA 178
+ +E + S K K K K++ EK + K+ + +E ++ + ++ KK
Sbjct: 79 KKEEPSQNDISPKTKSLRK--KKEPIEKKVVSSKTKKVTKNEEPSEEEIDAPKPKKMKKE 136
Query: 179 MENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLD 229
E GE +++ ++K G + + +P+EA E + E E+ P++
Sbjct: 137 KEMNGETREKSPKLKNG-----FPHPEPDCNPSEAASEESNSEIEQEIPVE 182
Score = 33.9 bits (76), Expect = 0.81
Identities = 17/48 (35%), Positives = 26/48 (54%)
Query: 74 RERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSK 121
RE R +R +R R R SRG R + S GNKS +++N+ + +
Sbjct: 728 REGSRGFRGQRDGNRRFRGQREGSRGPRGQRSGGGNKSNRSQNKGQKR 775
>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
Length = 406
Score = 195 bits (496), Expect = 2e-49
Identities = 133/447 (29%), Positives = 218/447 (48%), Gaps = 76/447 (17%)
Query: 372 KSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMF 431
K++ G++ + + + G+ KPT IQ +AIP + GRD+IG+A+TGSGKT AF LP+
Sbjct: 24 KTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL 83
Query: 432 RHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAE 491
+ LE + A+++TPTRELA QI+++ + ++G++ + GG Q
Sbjct: 84 NAL-----LETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLA 138
Query: 492 LKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVR 551
L + II+ TPGR+ID L G NLR + Y+V+DEADR+ +M FE +V +I+ +
Sbjct: 139 LAKKPHIIIATPGRLIDHLENTKG--FNLRALKYLVMDEADRILNMDFETEVDKILKVIP 196
Query: 552 PDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLE 611
DR+T +FSAT + ++ L R L P++ V + ++Q I I + K +L
Sbjct: 197 RDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIPSKFKSKRLGS 256
Query: 612 LLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCK 671
L ++ S+++ D
Sbjct: 257 LNKFKAKARSILLATD-------------------------------------------- 272
Query: 672 LLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYA 731
VA+RGLD+ H+ +VVN+ P H +DY+HR GRT RAG G A TF+T+ Y
Sbjct: 273 ------VASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ----YD 322
Query: 732 GDIIKALE-LSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANE 790
++ + +E L G +P F Q + ++ + + +F E E
Sbjct: 323 VELFQRIEHLIGKKLP--------GFPTQDDEVMMLTERVA----EAQRFARMELREHGE 370
Query: 791 RKKLQKAALGLQDSDDEDAAVDIDEQI 817
+KK + G D+DD + A+ + ++
Sbjct: 371 KKKRSREDAG--DNDDTEGAIGVRNKV 395
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,465,855
Number of Sequences: 37866
Number of extensions: 1860089
Number of successful extensions: 47750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 833
Number of HSP's successfully gapped in prelim test: 1013
Number of HSP's that attempted gapping in prelim test: 12333
Number of HSP's gapped (non-prelim): 13379
length of query: 1031
length of database: 18,247,518
effective HSP length: 112
effective length of query: 919
effective length of database: 14,006,526
effective search space: 12871997394
effective search space used: 12871997394
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.