Guide to the Human Genome
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Search of human proteins with 41327741

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41327741 ETHE1 protein [Homo sapiens]
         (254 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41327741 ETHE1 protein [Homo sapiens]                              517   e-147
gi|21703352 myofibrillogenesis regulator 1 isoform 2 [Homo sapiens]    75   7e-14
gi|116642887 myofibrillogenesis regulator 1 isoform 1 [Homo sapi...    75   7e-14
gi|46361987 hydroxyacylglutathione hydrolase-like isoform 1 [Hom...    72   4e-13
gi|14150041 hydroxyacylglutathione hydrolase-like isoform 2 [Hom...    72   4e-13
gi|94538320 hydroxyacylglutathione hydrolase isoform 2 [Homo sap...    69   3e-12
gi|94538322 hydroxyacylglutathione hydrolase isoform 1 [Homo sap...    69   3e-12
gi|7705793 lactamase, beta 2 [Homo sapiens]                            51   9e-07
gi|42822880 beta-lactamase-like [Homo sapiens]                         42   7e-04
gi|63025212 metallo-beta-lactamase domain containing 1 [Homo sap...    33   0.31 
gi|239743315 PREDICTED: hypothetical protein XP_002342820 [Homo ...    29   4.5  
gi|239508997 PREDICTED: hypothetical protein [Homo sapiens]            29   4.5  
gi|5032013 kinesin family member 20A [Homo sapiens]                    28   5.9  
gi|19557656 histone cluster 1, H2ab [Homo sapiens]                     28   7.7  
gi|15617199 histone cluster 3, H2a [Homo sapiens]                      28   7.7  
gi|10645195 histone cluster 1, H2ae [Homo sapiens]                     28   7.7  
gi|10800130 histone cluster 1, H2ad [Homo sapiens]                     28   7.7  

>gi|41327741 ETHE1 protein [Homo sapiens]
          Length = 254

 Score =  517 bits (1332), Expect = e-147
 Identities = 254/254 (100%), Positives = 254/254 (100%)

Query: 1   MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPR 60
           MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPR
Sbjct: 1   MAEAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPR 60

Query: 61  DAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLHIEDGDSI 120
           DAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLHIEDGDSI
Sbjct: 61  DAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLHIEDGDSI 120

Query: 121 RFGRFALETRASPGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHE 180
           RFGRFALETRASPGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHE
Sbjct: 121 RFGRFALETRASPGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHE 180

Query: 181 KIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFA 240
           KIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFA
Sbjct: 181 KIFTLPGDCLIYPAHDYHGFTVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFA 240

Query: 241 VPANMRCGVQTPTA 254
           VPANMRCGVQTPTA
Sbjct: 241 VPANMRCGVQTPTA 254


>gi|21703352 myofibrillogenesis regulator 1 isoform 2 [Homo sapiens]
          Length = 361

 Score = 74.7 bits (182), Expect = 7e-14
 Identities = 66/235 (28%), Positives = 105/235 (44%), Gaps = 45/235 (19%)

Query: 32  VSCTFTYLLGDRESREAVLIDPVLETAPRDAQL-IKELGLRLLYAVNTHCHADHITGSGL 90
           +S  ++YL+ D +++ AV +DP   + PR  Q  I++ G+ L+  + TH H DH  G+  
Sbjct: 103 LSDNYSYLIIDTQAQLAVAVDP---SDPRAVQASIEKEGVTLVAILCTHKHWDHSGGNRD 159

Query: 91  LRSLLPGCQSVISRLSGAQADLH-IEDGDSIRFGRFALETRASPGHTPGCVTFVLNDH-- 147
           L      C+   S   G     H +   D +  GR  +   A+PGHT G + ++L+    
Sbjct: 160 LSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPY 219

Query: 148 ---SMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDY------- 197
              S  F+GD L + GCGRT   +G A+T+  S+ + +  L  D L++P H+Y       
Sbjct: 220 KGPSCLFSGDLLFLSGCGRT--FEGNAETMLSSL-DTVLGLGDDTLLWPGHEYAEENLGF 276

Query: 198 -------------------------HGFTVSTVEEERTLNPRLTLSCEEFVKIMG 227
                                     G   ST+ EER+ NP L   C    + +G
Sbjct: 277 AGVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLALQEALG 331


>gi|116642887 myofibrillogenesis regulator 1 isoform 1 [Homo
           sapiens]
          Length = 385

 Score = 74.7 bits (182), Expect = 7e-14
 Identities = 66/235 (28%), Positives = 105/235 (44%), Gaps = 45/235 (19%)

Query: 32  VSCTFTYLLGDRESREAVLIDPVLETAPRDAQL-IKELGLRLLYAVNTHCHADHITGSGL 90
           +S  ++YL+ D +++ AV +DP   + PR  Q  I++ G+ L+  + TH H DH  G+  
Sbjct: 127 LSDNYSYLIIDTQAQLAVAVDP---SDPRAVQASIEKEGVTLVAILCTHKHWDHSGGNRD 183

Query: 91  LRSLLPGCQSVISRLSGAQADLH-IEDGDSIRFGRFALETRASPGHTPGCVTFVLNDH-- 147
           L      C+   S   G     H +   D +  GR  +   A+PGHT G + ++L+    
Sbjct: 184 LSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPY 243

Query: 148 ---SMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDY------- 197
              S  F+GD L + GCGRT   +G A+T+  S+ + +  L  D L++P H+Y       
Sbjct: 244 KGPSCLFSGDLLFLSGCGRT--FEGNAETMLSSL-DTVLGLGDDTLLWPGHEYAEENLGF 300

Query: 198 -------------------------HGFTVSTVEEERTLNPRLTLSCEEFVKIMG 227
                                     G   ST+ EER+ NP L   C    + +G
Sbjct: 301 AGVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLALQEALG 355


>gi|46361987 hydroxyacylglutathione hydrolase-like isoform 1 [Homo
           sapiens]
          Length = 290

 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 52/183 (28%), Positives = 90/183 (49%), Gaps = 13/183 (7%)

Query: 36  FTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLL 95
           + YL+ +  +REAV +D  +    R  +++   G+ L   + TH H DH  G+  L  L 
Sbjct: 13  YMYLVIEELTREAVAVD--VAVPKRLLEIVGREGVSLTAVLTTHHHWDHARGNPELARLR 70

Query: 96  PGCQSVISRLSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVL-----NDHSMA 150
           PG   + +          +  G+ +RFG   +    +PGHT G +++ L      D    
Sbjct: 71  PGLAVLGADERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDDCPDPPAL 130

Query: 151 FTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEERT 210
           F+GDAL + GCG     +G A+ +Y S+ E + TLP +  ++  H++   T+S +E  + 
Sbjct: 131 FSGDALSVAGCG--SCLEGSAQQMYQSLAE-LGTLPPETKVFCGHEH---TLSNLEFAQK 184

Query: 211 LNP 213
           + P
Sbjct: 185 VEP 187


>gi|14150041 hydroxyacylglutathione hydrolase-like isoform 2 [Homo
           sapiens]
          Length = 282

 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 52/183 (28%), Positives = 90/183 (49%), Gaps = 13/183 (7%)

Query: 36  FTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLL 95
           + YL+ +  +REAV +D  +    R  +++   G+ L   + TH H DH  G+  L  L 
Sbjct: 13  YMYLVIEELTREAVAVD--VAVPKRLLEIVGREGVSLTAVLTTHHHWDHARGNPELARLR 70

Query: 96  PGCQSVISRLSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVL-----NDHSMA 150
           PG   + +          +  G+ +RFG   +    +PGHT G +++ L      D    
Sbjct: 71  PGLAVLGADERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDDCPDPPAL 130

Query: 151 FTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEERT 210
           F+GDAL + GCG     +G A+ +Y S+ E + TLP +  ++  H++   T+S +E  + 
Sbjct: 131 FSGDALSVAGCG--SCLEGSAQQMYQSLAE-LGTLPPETKVFCGHEH---TLSNLEFAQK 184

Query: 211 LNP 213
           + P
Sbjct: 185 VEP 187


>gi|94538320 hydroxyacylglutathione hydrolase isoform 2 [Homo
           sapiens]
          Length = 260

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 12/183 (6%)

Query: 36  FTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLL 95
           + YL+ D E++EA ++DPV      DA   ++ G++L   + TH H DH  G+  L  L 
Sbjct: 13  YMYLVIDDETKEAAIVDPVQPQKVVDA--ARKHGVKLTTVLTTHHHWDHAGGNEKLVKLE 70

Query: 96  PGCQSVISRLSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVL-----NDHSMA 150
            G +              I    +++ G   ++  A+P HT G + + +     ++    
Sbjct: 71  SGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAV 130

Query: 151 FTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEERT 210
           FTGD L + GCG+  F +G A  +  ++ E +  LP D  +Y  H+Y   T++ ++  R 
Sbjct: 131 FTGDTLFVAGCGK--FYEGTADEMCKALLEVLGRLPPDTRVYCGHEY---TINNLKFARH 185

Query: 211 LNP 213
           + P
Sbjct: 186 VEP 188


>gi|94538322 hydroxyacylglutathione hydrolase isoform 1 [Homo
           sapiens]
          Length = 308

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 12/183 (6%)

Query: 36  FTYLLGDRESREAVLIDPVLETAPRDAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLL 95
           + YL+ D E++EA ++DPV      DA   ++ G++L   + TH H DH  G+  L  L 
Sbjct: 61  YMYLVIDDETKEAAIVDPVQPQKVVDA--ARKHGVKLTTVLTTHHHWDHAGGNEKLVKLE 118

Query: 96  PGCQSVISRLSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVL-----NDHSMA 150
            G +              I    +++ G   ++  A+P HT G + + +     ++    
Sbjct: 119 SGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAV 178

Query: 151 FTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEERT 210
           FTGD L + GCG+  F +G A  +  ++ E +  LP D  +Y  H+Y   T++ ++  R 
Sbjct: 179 FTGDTLFVAGCGK--FYEGTADEMCKALLEVLGRLPPDTRVYCGHEY---TINNLKFARH 233

Query: 211 LNP 213
           + P
Sbjct: 234 VEP 236


>gi|7705793 lactamase, beta 2 [Homo sapiens]
          Length = 288

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 56/211 (26%), Positives = 92/211 (43%), Gaps = 35/211 (16%)

Query: 3   EAVLRVARRQLSQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLETAPRDA 62
           + V R++ R +   G +  P+ L+        T TYL+G    R  +LID      P   
Sbjct: 6   QRVERLSNRVVRVLGCNPGPMTLQG-------TNTYLVGTGPRR--ILIDTGEPAIPEYI 56

Query: 63  QLIK----ELGLRLLYAVNTHCHADHITGSG-LLRSLLPGCQSVISRL-----------S 106
             +K    E    +   V TH H DH  G G + +S+       I +L           +
Sbjct: 57  SCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGN 116

Query: 107 GAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVLNDHSMAFTGDALLIRGCGRTDF 166
           G Q  ++++DGD I+     L    +PGHT   +  +L + +  F+GD +L  G G T F
Sbjct: 117 GEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCIL--GEGTTVF 174

Query: 167 QQGCAKTLYHSVH--EKIFTLPGDCLIYPAH 195
           +      LY  ++  +++  +  D +IYP H
Sbjct: 175 ED-----LYDYMNSLKELLKIKAD-IIYPGH 199


>gi|42822880 beta-lactamase-like [Homo sapiens]
          Length = 279

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 32/128 (25%), Positives = 49/128 (38%), Gaps = 31/128 (24%)

Query: 60  RDAQLIKELGLRLLYAVNTHCHADHITG-------------------------------S 88
           +D +  ++   R L AV TH H DH  G                               S
Sbjct: 64  QDREAKEDAARRPLLAVATHVHFDHSGGLYQFDRVAVHHAEAEALARGDNFETVTWLSDS 123

Query: 89  GLLRSLLPGCQSVISRLSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVLNDHS 148
            ++R+  PG ++   R+   Q  L ++DGD I  G   L     PGH+ G +     D  
Sbjct: 124 EVVRAPSPGWRARQFRVQAVQPTLILQDGDVINLGDRQLTVMHMPGHSRGSICLHDKDRK 183

Query: 149 MAFTGDAL 156
           + F+GD +
Sbjct: 184 ILFSGDVV 191


>gi|63025212 metallo-beta-lactamase domain containing 1 [Homo
           sapiens]
          Length = 266

 Score = 32.7 bits (73), Expect = 0.31
 Identities = 40/127 (31%), Positives = 53/127 (41%), Gaps = 23/127 (18%)

Query: 14  SQRGGSGAPILLRQMFEPVSCTFTYLLGDRESREAVLIDPVLE-TAPRDAQLIKELGLRL 72
           S RG  GA   L +         T   G   +REA+L     +  AP D  L+       
Sbjct: 61  SPRGSGGAEAALEEAARGPILVDT---GGPWAREALLGALAGQGVAPGDVTLV------- 110

Query: 73  LYAVNTHCHADHITGSGLLRSLLPGCQSVISR---LSGAQADLH-IEDGDSIRFGRFALE 128
              V TH H+DHI   G    L PG   ++S    L G +   H + +G  +R G   LE
Sbjct: 111 ---VGTHGHSDHIGNLG----LFPGAALLVSHDFCLPGGRYLPHGLGEGQPLRLGP-GLE 162

Query: 129 TRASPGH 135
             A+PGH
Sbjct: 163 VWATPGH 169


>gi|239743315 PREDICTED: hypothetical protein XP_002342820 [Homo
           sapiens]
          Length = 248

 Score = 28.9 bits (63), Expect = 4.5
 Identities = 20/70 (28%), Positives = 32/70 (45%)

Query: 55  LETAPRDAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLHI 114
           L  APR A+ +  L      +V   C  +H+ G+G +     G +    R SG+ +    
Sbjct: 170 LSRAPRWARSVCALCSSTSASVCGRCSLEHLRGTGRVGRGGRGQRQGHDRNSGSHSSQDT 229

Query: 115 EDGDSIRFGR 124
           + GD+ R GR
Sbjct: 230 DTGDNTRVGR 239


>gi|239508997 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 28.9 bits (63), Expect = 4.5
 Identities = 20/70 (28%), Positives = 32/70 (45%)

Query: 55  LETAPRDAQLIKELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLSGAQADLHI 114
           L  APR A+ +  L      +V   C  +H+ G+G +     G +    R SG+ +    
Sbjct: 170 LSRAPRWARSVCALCSSTSASVCGRCSLEHLRGTGRVGRGGRGQRQGHDRNSGSHSSQDT 229

Query: 115 EDGDSIRFGR 124
           + GD+ R GR
Sbjct: 230 DTGDNTRVGR 239


>gi|5032013 kinesin family member 20A [Homo sapiens]
          Length = 890

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 7/66 (10%)

Query: 51  IDPVLETAPRDAQLIK----ELGLRLLYAVNTHCHADHITGSGLLRSLLPGCQSVISRLS 106
           +D  LE   ++ +L++    +LG  L  A    CH+   TG+G LR  L  C  ++ +  
Sbjct: 730 VDKKLEEGQKNIRLLRTELQKLGESLQSAERACCHS---TGAGKLRQALTTCDDILIKQD 786

Query: 107 GAQADL 112
              A+L
Sbjct: 787 QTLAEL 792


>gi|19557656 histone cluster 1, H2ab [Homo sapiens]
          Length = 130

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 3/59 (5%)

Query: 14 SQRGGSGAPILLRQMFEPVSCTFTYLLGD--RESREAVLIDPVLETAPR-DAQLIKELG 69
          S+R G+GAP+ L  + E ++     L G+  R++++  +I   L+ A R D +L K LG
Sbjct: 41 SERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG 99


>gi|15617199 histone cluster 3, H2a [Homo sapiens]
          Length = 130

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 3/59 (5%)

Query: 14 SQRGGSGAPILLRQMFEPVSCTFTYLLGD--RESREAVLIDPVLETAPR-DAQLIKELG 69
          S+R G+GAP+ L  + E ++     L G+  R++++  +I   L+ A R D +L K LG
Sbjct: 41 SERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG 99


>gi|10645195 histone cluster 1, H2ae [Homo sapiens]
          Length = 130

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 3/59 (5%)

Query: 14 SQRGGSGAPILLRQMFEPVSCTFTYLLGD--RESREAVLIDPVLETAPR-DAQLIKELG 69
          S+R G+GAP+ L  + E ++     L G+  R++++  +I   L+ A R D +L K LG
Sbjct: 41 SERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG 99


>gi|10800130 histone cluster 1, H2ad [Homo sapiens]
          Length = 130

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 3/59 (5%)

Query: 14 SQRGGSGAPILLRQMFEPVSCTFTYLLGD--RESREAVLIDPVLETAPR-DAQLIKELG 69
          S+R G+GAP+ L  + E ++     L G+  R++++  +I   L+ A R D +L K LG
Sbjct: 41 SERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG 99


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,199,054
Number of Sequences: 37866
Number of extensions: 453941
Number of successful extensions: 900
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 876
Number of HSP's gapped (non-prelim): 20
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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