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Search of human proteins with 40805843
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
(832 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 1690 0.0
gi|153791535 general control of amino acid synthesis 5-like 2 [H... 1174 0.0
gi|38788260 bromodomain PHD finger transcription factor isoform ... 114 3e-25
gi|38788274 bromodomain PHD finger transcription factor isoform ... 114 3e-25
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 94 5e-19
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 89 2e-17
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 89 2e-17
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 86 1e-16
gi|164419758 bromodomain containing 2 [Homo sapiens] 84 4e-16
gi|4826806 bromodomain containing 2 [Homo sapiens] 84 4e-16
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 83 1e-15
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 80 1e-14
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 80 1e-14
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 76 1e-13
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 68 3e-11
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 68 3e-11
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 67 7e-11
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 67 9e-11
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 67 9e-11
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 65 3e-10
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 64 4e-10
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 64 4e-10
gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 60 6e-09
gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 60 6e-09
gi|41281917 polybromo 1 isoform 4 [Homo sapiens] 60 6e-09
gi|41350212 bromodomain containing 7 [Homo sapiens] 59 1e-08
gi|11321642 bromodomain containing protein 1 [Homo sapiens] 59 2e-08
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] 57 5e-08
gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens] 57 5e-08
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 57 7e-08
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 1690 bits (4376), Expect = 0.0
Identities = 832/832 (100%), Positives = 832/832 (100%)
Query: 1 MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAA 60
MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAA
Sbjct: 1 MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAA 60
Query: 61 AGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTP 120
AGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTP
Sbjct: 61 AGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTP 120
Query: 121 PRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEED 180
PRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEED
Sbjct: 121 PRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEED 180
Query: 181 ADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKE 240
ADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKE
Sbjct: 181 ADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKE 240
Query: 241 RQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR 300
RQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR
Sbjct: 241 RQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR 300
Query: 301 YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQ 360
YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQ
Sbjct: 301 YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQ 360
Query: 361 NSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSG 420
NSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSG
Sbjct: 361 NSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSG 420
Query: 421 LEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSA 480
LEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSA
Sbjct: 421 LEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSA 480
Query: 481 RDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFD 540
RDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFD
Sbjct: 481 RDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFD 540
Query: 541 PKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH 600
PKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH
Sbjct: 541 PKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH 600
Query: 601 DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFS 660
DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFS
Sbjct: 601 DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFS 660
Query: 661 VIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSK 720
VIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSK
Sbjct: 661 VIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSK 720
Query: 721 EPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNR 780
EPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNR
Sbjct: 721 EPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNR 780
Query: 781 YYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK 832
YYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK
Sbjct: 781 YYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK 832
>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
sapiens]
Length = 837
Score = 1174 bits (3038), Expect = 0.0
Identities = 586/813 (72%), Positives = 667/813 (82%), Gaps = 14/813 (1%)
Query: 27 PQPAALP---PAP-PQGSPCAAAAGGSGACGPATAVAAAGTAEGPGGGGSA---RIAVKK 79
P PA+ P P P P +P AA AG +G GP AG+ P G + R + +K
Sbjct: 32 PSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPARPGLSQQQRASQRK 91
Query: 80 AQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRADLQQIIVSLTESCRSC 139
AQ+R PRAKKLEKLGV+SACKA E+CKCNGWKNP P PT PR DLQQ +L+E CRSC
Sbjct: 92 AQVRGLPRAKKLEKLGVFSACKANETCKCNGWKNPKP-PTAPRMDLQQPAANLSELCRSC 150
Query: 140 SHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSIL 199
H LA HVSHLENVSE+E+NRLLG+V+DVE LF VHKEED DTKQVYFYLFKLLRK IL
Sbjct: 151 EHPLADHVSHLENVSEDEINRLLGMVVDVENLFMSVHKEEDTDTKQVYFYLFKLLRKCIL 210
Query: 200 QRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKMFLNRINYWH 259
Q +PVVEGSL PPFEKP+IEQGV NFVQYKFSHL +ERQT+ EL+KMFL +NYW
Sbjct: 211 QMTRPVVEGSL-GSPPFEKPNIEQGVLNFVQYKFSHLAPRERQTMFELSKMFLLCLNYWK 269
Query: 260 LEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRTLLRSVFTVM 319
LE P+Q R RS +D++ YK NYTRWLCYC+VPQ CDSLPRYETT VFGR+LLRS+FTV
Sbjct: 270 LETPAQFRQRSQAEDVATYKVNYTRWLCYCHVPQSCDSLPRYETTHVFGRSLLRSIFTVT 329
Query: 320 RRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSQL 379
RRQLLE+ R EKDKL EKRTLILTHFPKFLSMLEEE+Y NSPIW+ F S
Sbjct: 330 RRQLLEKFRVEKDKLVPEKRTLILTHFPKFLSMLEEEIYGANSPIWESGFTMPPSE---- 385
Query: 380 GIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRKMTDSHVLEE 439
G Q V P V+ + ST GS+S S+G E PGEKR + ++ LE+
Sbjct: 386 GTQLVPRPASVSAAV-VPSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLED 444
Query: 440 AKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEERRGVIEFHVV 499
AK+ RVMGDIPMEL+NEVM TITDPAAMLGPET+ LSA++ARDE ARLEERRG+IEFHV+
Sbjct: 445 AKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVI 504
Query: 500 GNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGIC 559
GNSL K N+++L+WLVGLQNVFSHQLPRMPKEYI RLVFDPKHKTLALIKDGRVIGGIC
Sbjct: 505 GNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGIC 564
Query: 560 FRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYADEYAIGYFKK 619
FRMFP+QGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH+IL FLTYADEYAIGYFKK
Sbjct: 565 FRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKK 624
Query: 620 QGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIKKLIERKQA 679
QGFSK+IK+PK++Y+GYIKDYEGATLM CELNPRIPYTE S IIKKQKEIIKKLIERKQA
Sbjct: 625 QGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQA 684
Query: 680 QIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQV 739
QIRKVYPGLSCFK+GVRQIP+ES+PGIRETGWKP GKEK KE +DPDQLY+TLK++L Q+
Sbjct: 685 QIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQI 744
Query: 740 KSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNC 799
KSH SAWPFMEPVK++EAP YYEVIRFP+DLKTM+ERL++RYYV++KLF+ADLQRV NC
Sbjct: 745 KSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANC 804
Query: 800 KEYNPPESEYYKCANILEKFFFSKIKEAGLIDK 832
+EYNPP+SEY +CA+ LEKFF+ K+KE GLIDK
Sbjct: 805 REYNPPDSEYCRCASALEKFFYFKLKEGGLIDK 837
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 114 bits (286), Expect = 3e-25
Identities = 48/97 (49%), Positives = 69/97 (71%)
Query: 729 YSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLF 788
Y LK +L+ +++H+ AWPF+EPV +AP YY VI+ PMDL TM ER++ RYY F
Sbjct: 2790 YEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEF 2849
Query: 789 MADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIK 825
+AD+ ++F NC+ YNP +S +Y+CA +LE FF K+K
Sbjct: 2850 VADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2886
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 114 bits (286), Expect = 3e-25
Identities = 48/97 (49%), Positives = 69/97 (71%)
Query: 729 YSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLF 788
Y LK +L+ +++H+ AWPF+EPV +AP YY VI+ PMDL TM ER++ RYY F
Sbjct: 2807 YEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEF 2866
Query: 789 MADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIK 825
+AD+ ++F NC+ YNP +S +Y+CA +LE FF K+K
Sbjct: 2867 VADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2903
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 94.0 bits (232), Expect = 5e-19
Identities = 39/105 (37%), Positives = 71/105 (67%)
Query: 716 KEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSE 775
++K+K+ + D ++ + +L VK+H+ +WPF+EPV + AP YY++I+ PMD+ +M +
Sbjct: 427 EKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEK 486
Query: 776 RLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFF 820
+L Y +K+ F+ D++ +F NC++YN SEY K ++ LE+ F
Sbjct: 487 KLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCF 531
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 89.0 bits (219), Expect = 2e-17
Identities = 44/116 (37%), Positives = 64/116 (55%), Gaps = 2/116 (1%)
Query: 713 PSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVK--RTEAPGYYEVIRFPMDL 770
P +K R +QL L+ +L+ + HQ AWPF +PV + P YY++I+ PMD+
Sbjct: 48 PETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDM 107
Query: 771 KTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
T+ +RL+N YY + + + D +FTNC YN P + A LEK F KI E
Sbjct: 108 GTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE 163
Score = 62.4 bits (150), Expect = 2e-09
Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 5/85 (5%)
Query: 740 KSHQS-AWPFMEPVKRTEAPG---YYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRV 795
K H + AWPF +PV EA G Y ++I+ PMD+ T+ +L+ R Y + F AD++ +
Sbjct: 367 KKHAAYAWPFYKPVD-VEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLM 425
Query: 796 FTNCKEYNPPESEYYKCANILEKFF 820
F+NC +YNPP+ E A L+ F
Sbjct: 426 FSNCYKYNPPDHEVVAMARKLQDVF 450
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 89.0 bits (219), Expect = 2e-17
Identities = 44/116 (37%), Positives = 64/116 (55%), Gaps = 2/116 (1%)
Query: 713 PSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVK--RTEAPGYYEVIRFPMDL 770
P +K R +QL L+ +L+ + HQ AWPF +PV + P YY++I+ PMD+
Sbjct: 48 PETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDM 107
Query: 771 KTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
T+ +RL+N YY + + + D +FTNC YN P + A LEK F KI E
Sbjct: 108 GTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE 163
Score = 62.4 bits (150), Expect = 2e-09
Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 5/85 (5%)
Query: 740 KSHQS-AWPFMEPVKRTEAPG---YYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRV 795
K H + AWPF +PV EA G Y ++I+ PMD+ T+ +L+ R Y + F AD++ +
Sbjct: 367 KKHAAYAWPFYKPVD-VEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLM 425
Query: 796 FTNCKEYNPPESEYYKCANILEKFF 820
F+NC +YNPP+ E A L+ F
Sbjct: 426 FSNCYKYNPPDHEVVAMARKLQDVF 450
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 85.9 bits (211), Expect = 1e-16
Identities = 47/123 (38%), Positives = 67/123 (54%), Gaps = 1/123 (0%)
Query: 704 PGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEV 763
P E G PS K + R+ + + IL +++SH +AWPF+EPV GY +
Sbjct: 1775 PRYSEEGLSPS-KRRRLSMRNHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRI 1833
Query: 764 IRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSK 823
I+ PMD TM ERL Y S + F AD VF NC+ +N +SE K +I+ +FF S+
Sbjct: 1834 IKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESR 1893
Query: 824 IKE 826
+E
Sbjct: 1894 WEE 1896
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 84.3 bits (207), Expect = 4e-16
Identities = 48/141 (34%), Positives = 71/141 (50%), Gaps = 5/141 (3%)
Query: 689 SCFKDGVRQIPIESIPGIRETGWKPSGKEKS---KEPRDPDQLYSTLKSILQQVKSHQSA 745
S +G + S+P ++ T P E S K R +QL K +++ + HQ A
Sbjct: 37 SLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFA 96
Query: 746 WPFMEPVKRTEA--PGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYN 803
WPF +PV + P Y+++I+ PMD+ T+ RL+N YY + M D +FTNC YN
Sbjct: 97 WPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
Query: 804 PPESEYYKCANILEKFFFSKI 824
P + A LEK F K+
Sbjct: 157 KPTDDIVLMAQTLEKIFLQKV 177
Score = 67.8 bits (164), Expect = 4e-11
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 16/174 (9%)
Query: 663 IKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEP 722
+ K+K + +K + PG G + +P +R +P + P
Sbjct: 273 LAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLP 332
Query: 723 RDPDQLYSTLKSILQQVKSHQS--------------AWPFMEPVKRTEAP--GYYEVIRF 766
Q S+ K L + H + AWPF +PV + Y+++I+
Sbjct: 333 DSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKH 392
Query: 767 PMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFF 820
PMDL T+ +++NR Y + F AD++ +F+NC +YNPP+ + A L+ F
Sbjct: 393 PMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVF 446
Score = 30.4 bits (67), Expect = 7.1
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 10/69 (14%)
Query: 18 AGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAAAGTAEGPGGGGSARIAV 77
AGA P+ A PP P + + + GGS A GP + GP GG ++
Sbjct: 567 AGADEDDKGPR-APRPPQPKKSKKASGSGGGSAALGP--------SGFGPSGGSGTKLP- 616
Query: 78 KKAQLRSAP 86
KKA + P
Sbjct: 617 KKATKTAPP 625
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 84.3 bits (207), Expect = 4e-16
Identities = 48/141 (34%), Positives = 71/141 (50%), Gaps = 5/141 (3%)
Query: 689 SCFKDGVRQIPIESIPGIRETGWKPSGKEKS---KEPRDPDQLYSTLKSILQQVKSHQSA 745
S +G + S+P ++ T P E S K R +QL K +++ + HQ A
Sbjct: 37 SLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFA 96
Query: 746 WPFMEPVKRTEA--PGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYN 803
WPF +PV + P Y+++I+ PMD+ T+ RL+N YY + M D +FTNC YN
Sbjct: 97 WPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
Query: 804 PPESEYYKCANILEKFFFSKI 824
P + A LEK F K+
Sbjct: 157 KPTDDIVLMAQTLEKIFLQKV 177
Score = 67.8 bits (164), Expect = 4e-11
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 16/174 (9%)
Query: 663 IKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEP 722
+ K+K + +K + PG G + +P +R +P + P
Sbjct: 273 LAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLP 332
Query: 723 RDPDQLYSTLKSILQQVKSHQS--------------AWPFMEPVKRTEAP--GYYEVIRF 766
Q S+ K L + H + AWPF +PV + Y+++I+
Sbjct: 333 DSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKH 392
Query: 767 PMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFF 820
PMDL T+ +++NR Y + F AD++ +F+NC +YNPP+ + A L+ F
Sbjct: 393 PMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVF 446
Score = 30.4 bits (67), Expect = 7.1
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 10/69 (14%)
Query: 18 AGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAAAGTAEGPGGGGSARIAV 77
AGA P+ A PP P + + + GGS A GP + GP GG ++
Sbjct: 567 AGADEDDKGPR-APRPPQPKKSKKASGSGGGSAALGP--------SGFGPSGGSGTKLP- 616
Query: 78 KKAQLRSAP 86
KKA + P
Sbjct: 617 KKATKTAPP 625
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 82.8 bits (203), Expect = 1e-15
Identities = 42/116 (36%), Positives = 61/116 (52%), Gaps = 2/116 (1%)
Query: 713 PSGKEKSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVK--RTEAPGYYEVIRFPMDL 770
P SK R +QL +++ + HQ AWPF +PV + P Y+++I+ PMD+
Sbjct: 24 PEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDM 83
Query: 771 KTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
T+ +RL+N YY S M D +FTNC YN P + A LEK F K+ +
Sbjct: 84 GTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQ 139
Score = 66.6 bits (161), Expect = 9e-11
Identities = 35/92 (38%), Positives = 56/92 (60%), Gaps = 5/92 (5%)
Query: 734 SILQQV--KSHQS-AWPFMEPV--KRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLF 788
SIL+++ K H + AWPF +PV + E Y+++I+ PMDL T+ ++ R Y + F
Sbjct: 317 SILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGF 376
Query: 789 MADLQRVFTNCKEYNPPESEYYKCANILEKFF 820
AD++ +F+NC +YNPP+ E A L+ F
Sbjct: 377 AADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 408
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 79.7 bits (195), Expect = 1e-14
Identities = 39/109 (35%), Positives = 58/109 (53%), Gaps = 2/109 (1%)
Query: 720 KEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVK--RTEAPGYYEVIRFPMDLKTMSERL 777
K R +QL K +L+ + H +WPF PV + + P YY +I+ PMDL T+ +RL
Sbjct: 24 KNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRL 83
Query: 778 KNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
+N+YY + D +F+NC YN P + A LEK F K+ +
Sbjct: 84 ENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQ 132
Score = 68.6 bits (166), Expect = 2e-11
Identities = 41/99 (41%), Positives = 57/99 (57%), Gaps = 8/99 (8%)
Query: 732 LKSILQQVKSHQSAWPFMEPVKRTEAPG---YYEVIRFPMDLKTMSERLKNRYYVSKKLF 788
LK +L + K AWPF PV A G YY+V++ PMDL T+ E++ N+ Y F
Sbjct: 280 LKEMLAK-KHFSYAWPFYNPVD-VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKF 337
Query: 789 MADLQRVFTNCKEYNPPESEYYKCANILEKFF---FSKI 824
AD++ +F NC +YNPP+ E A +L+ F FSKI
Sbjct: 338 AADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKI 376
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 79.7 bits (195), Expect = 1e-14
Identities = 39/109 (35%), Positives = 58/109 (53%), Gaps = 2/109 (1%)
Query: 720 KEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVK--RTEAPGYYEVIRFPMDLKTMSERL 777
K R +QL K +L+ + H +WPF PV + + P YY +I+ PMDL T+ +RL
Sbjct: 24 KNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRL 83
Query: 778 KNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
+N+YY + D +F+NC YN P + A LEK F K+ +
Sbjct: 84 ENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQ 132
Score = 68.6 bits (166), Expect = 2e-11
Identities = 41/99 (41%), Positives = 57/99 (57%), Gaps = 8/99 (8%)
Query: 732 LKSILQQVKSHQSAWPFMEPVKRTEAPG---YYEVIRFPMDLKTMSERLKNRYYVSKKLF 788
LK +L + K AWPF PV A G YY+V++ PMDL T+ E++ N+ Y F
Sbjct: 280 LKEMLAK-KHFSYAWPFYNPVD-VNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKF 337
Query: 789 MADLQRVFTNCKEYNPPESEYYKCANILEKFF---FSKI 824
AD++ +F NC +YNPP+ E A +L+ F FSKI
Sbjct: 338 AADVRLMFMNCYKYNPPDHEVVTMARMLQDVFETHFSKI 376
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 76.3 bits (186), Expect = 1e-13
Identities = 35/104 (33%), Positives = 60/104 (57%)
Query: 720 KEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKN 779
K RD + + IL ++++H+ AWPF+ PV PGY +VI+ PMD T+ E+L +
Sbjct: 2057 KPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSS 2116
Query: 780 RYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSK 823
Y + + F D++ VF NC+ +N +S+ + + + K+F K
Sbjct: 2117 GQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 68.2 bits (165), Expect = 3e-11
Identities = 29/100 (29%), Positives = 56/100 (56%)
Query: 730 STLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFM 789
S + ++ ++ H +WPF++ V + + P YY++I+ P+ L + E++ Y F+
Sbjct: 1404 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1463
Query: 790 ADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGL 829
D++ +F+NC EYNP + K L+ FF + ++ GL
Sbjct: 1464 DDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGL 1503
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 68.2 bits (165), Expect = 3e-11
Identities = 29/100 (29%), Positives = 56/100 (56%)
Query: 730 STLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFM 789
S + ++ ++ H +WPF++ V + + P YY++I+ P+ L + E++ Y F+
Sbjct: 1436 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1495
Query: 790 ADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGL 829
D++ +F+NC EYNP + K L+ FF + ++ GL
Sbjct: 1496 DDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGL 1535
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 67.0 bits (162), Expect = 7e-11
Identities = 31/80 (38%), Positives = 47/80 (58%)
Query: 733 KSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADL 792
+ IL ++ ++ +WPF EPV R EA YY+VI PMD +T+ + Y S + F+ D+
Sbjct: 1349 EEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDM 1408
Query: 793 QRVFTNCKEYNPPESEYYKC 812
++VFTN + YN S C
Sbjct: 1409 KQVFTNAEVYNCRGSHVLSC 1428
>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
Length = 1872
Score = 66.6 bits (161), Expect = 9e-11
Identities = 30/92 (32%), Positives = 51/92 (55%)
Query: 735 ILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQR 794
+ Q++ + +WPF PV + P YY+VI PMDL+T+ + + Y S++ F+ D+
Sbjct: 1515 VTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNL 1574
Query: 795 VFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
+ N +YN PES+Y K A + + + E
Sbjct: 1575 ILANSVKYNGPESQYTKTAQEIVNVCYQTLTE 1606
Score = 58.5 bits (140), Expect = 2e-08
Identities = 30/99 (30%), Positives = 51/99 (51%)
Query: 728 LYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKL 787
L S L+SI+ ++ + +PF PV YY++I PMDL+T+ E ++ R Y S++
Sbjct: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1444
Query: 788 FMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
F L+ + N YN P+ + + + K+KE
Sbjct: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE 1483
>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
Length = 1893
Score = 66.6 bits (161), Expect = 9e-11
Identities = 30/92 (32%), Positives = 51/92 (55%)
Query: 735 ILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQR 794
+ Q++ + +WPF PV + P YY+VI PMDL+T+ + + Y S++ F+ D+
Sbjct: 1536 VTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNL 1595
Query: 795 VFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
+ N +YN PES+Y K A + + + E
Sbjct: 1596 ILANSVKYNGPESQYTKTAQEIVNVCYQTLTE 1627
Score = 58.5 bits (140), Expect = 2e-08
Identities = 30/99 (30%), Positives = 51/99 (51%)
Query: 728 LYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKL 787
L S L+SI+ ++ + +PF PV YY++I PMDL+T+ E ++ R Y S++
Sbjct: 1406 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1465
Query: 788 FMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
F L+ + N YN P+ + + + K+KE
Sbjct: 1466 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE 1504
>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
sapiens]
Length = 1826
Score = 65.1 bits (157), Expect = 3e-10
Identities = 29/92 (31%), Positives = 51/92 (55%)
Query: 735 ILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQR 794
+ Q++ + +WPF PV + P YY++I P+DL+T+ + + Y S++ F+ D+
Sbjct: 1534 VTQKMMAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNL 1593
Query: 795 VFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
+ N +YN PES+Y K A + + I E
Sbjct: 1594 ILANSVKYNGPESQYTKTAQEIVNICYQTITE 1625
Score = 53.9 bits (128), Expect = 6e-07
Identities = 29/99 (29%), Positives = 49/99 (49%)
Query: 728 LYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKL 787
L S L+SI+ ++ + PF PV YY++I PMDL+T+ E ++ Y S++
Sbjct: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREE 1463
Query: 788 FMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
F L+ + N YN P+ + + + K+KE
Sbjct: 1464 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE 1502
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 64.3 bits (155), Expect = 4e-10
Identities = 33/86 (38%), Positives = 50/86 (58%), Gaps = 3/86 (3%)
Query: 742 HQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRY--YVSKKLFMADLQRVFTNC 799
H+ + F +PV T P YY++I+ PMDL T+ +RL+ Y Y + F+AD + +F NC
Sbjct: 918 HEMSLAFQDPVPLT-VPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNC 976
Query: 800 KEYNPPESEYYKCANILEKFFFSKIK 825
E+N P+SE LE +F +K
Sbjct: 977 AEFNEPDSEVANAGIKLENYFEELLK 1002
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 64.3 bits (155), Expect = 4e-10
Identities = 33/86 (38%), Positives = 50/86 (58%), Gaps = 3/86 (3%)
Query: 742 HQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRY--YVSKKLFMADLQRVFTNC 799
H+ + F +PV T P YY++I+ PMDL T+ +RL+ Y Y + F+AD + +F NC
Sbjct: 884 HEMSLAFQDPVPLT-VPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNC 942
Query: 800 KEYNPPESEYYKCANILEKFFFSKIK 825
E+N P+SE LE +F +K
Sbjct: 943 AEFNEPDSEVANAGIKLENYFEELLK 968
>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
Length = 1602
Score = 60.5 bits (145), Expect = 6e-09
Identities = 52/222 (23%), Positives = 97/222 (43%), Gaps = 22/222 (9%)
Query: 618 KKQGFSKEIKIP------KTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIK 671
K + ++IK+P +TK ++YE + C+LN + + I K
Sbjct: 384 KYPDYYQQIKMPISLQQIRTKLKN--QEYETLDHLECDLN--LMFENAKRYNVPNSAIYK 439
Query: 672 KLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQ---- 727
++++ +Q K K+ R+ IE + + +G K K ++ +
Sbjct: 440 RVLKLQQVMQAKK-------KELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMK 492
Query: 728 -LYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
L++ + + + FM + + P YY++I PMDLK + ++N Y ++
Sbjct: 493 ILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEE 552
Query: 787 LFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAG 828
+ D++ +F N + YN S+ Y A+ILEK K KE G
Sbjct: 553 GMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELG 594
Score = 60.1 bits (144), Expect = 8e-09
Identities = 28/79 (35%), Positives = 46/79 (58%)
Query: 748 FMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPES 807
F + + + P YY +I+ P+DLKT+++R++N Y S D+ + N K YN P S
Sbjct: 208 FQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGS 267
Query: 808 EYYKCANILEKFFFSKIKE 826
+ +K AN ++K F+ K E
Sbjct: 268 QVFKDANSIKKIFYMKKAE 286
Score = 55.8 bits (133), Expect = 2e-07
Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Query: 727 QLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
+LY+T++ + + F+ KR P YYEV+ P+DL + ++LK Y
Sbjct: 52 ELYNTIRDYKDE-QGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVN 110
Query: 787 LFMADLQRVFTNCKEYNPPESEYYKCA 813
L AD Q +F N K Y P+S YK A
Sbjct: 111 LLTADFQLLFNNAKSYYKPDSPEYKAA 137
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 727 QLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
QLY T++S + A PF + + P YY+ I+ P+ L+ + +LKN+ Y +
Sbjct: 356 QLYDTVRSCRNN-QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLD 414
Query: 787 LFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
DL +F N K YN P S YK L++ +K KE
Sbjct: 415 HLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKE 454
Score = 47.8 bits (112), Expect = 4e-05
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
Query: 707 RETGWKPSGKEKSKEPRDP--DQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVI 764
R++G P K K P +++Y +K+ + SA F+ R+E P YY I
Sbjct: 611 RKSGISPK-KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI-FLRLPSRSELPDYYLTI 668
Query: 765 RFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEK 818
+ PMD++ + + Y + D +F N YN PES YK A +L K
Sbjct: 669 KKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHK 722
>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
Length = 1582
Score = 60.5 bits (145), Expect = 6e-09
Identities = 52/222 (23%), Positives = 97/222 (43%), Gaps = 22/222 (9%)
Query: 618 KKQGFSKEIKIP------KTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIK 671
K + ++IK+P +TK ++YE + C+LN + + I K
Sbjct: 416 KYPDYYQQIKMPISLQQIRTKLKN--QEYETLDHLECDLN--LMFENAKRYNVPNSAIYK 471
Query: 672 KLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQ---- 727
++++ +Q K K+ R+ IE + + +G K K ++ +
Sbjct: 472 RVLKLQQVMQAKK-------KELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMK 524
Query: 728 -LYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
L++ + + + FM + + P YY++I PMDLK + ++N Y ++
Sbjct: 525 ILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEE 584
Query: 787 LFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAG 828
+ D++ +F N + YN S+ Y A+ILEK K KE G
Sbjct: 585 GMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELG 626
Score = 60.1 bits (144), Expect = 8e-09
Identities = 28/79 (35%), Positives = 46/79 (58%)
Query: 748 FMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPES 807
F + + + P YY +I+ P+DLKT+++R++N Y S D+ + N K YN P S
Sbjct: 208 FQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGS 267
Query: 808 EYYKCANILEKFFFSKIKE 826
+ +K AN ++K F+ K E
Sbjct: 268 QVFKDANSIKKIFYMKKAE 286
Score = 55.8 bits (133), Expect = 2e-07
Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Query: 727 QLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
+LY+T++ + + F+ KR P YYEV+ P+DL + ++LK Y
Sbjct: 52 ELYNTIRDYKDE-QGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVN 110
Query: 787 LFMADLQRVFTNCKEYNPPESEYYKCA 813
L AD Q +F N K Y P+S YK A
Sbjct: 111 LLTADFQLLFNNAKSYYKPDSPEYKAA 137
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 727 QLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
QLY T++S + A PF + + P YY+ I+ P+ L+ + +LKN+ Y +
Sbjct: 388 QLYDTVRSCRNN-QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLD 446
Query: 787 LFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
DL +F N K YN P S YK L++ +K KE
Sbjct: 447 HLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKE 486
Score = 47.8 bits (112), Expect = 4e-05
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
Query: 707 RETGWKPSGKEKSKEPRDP--DQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVI 764
R++G P K K P +++Y +K+ + SA F+ R+E P YY I
Sbjct: 643 RKSGISPK-KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI-FLRLPSRSELPDYYLTI 700
Query: 765 RFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEK 818
+ PMD++ + + Y + D +F N YN PES YK A +L K
Sbjct: 701 KKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHK 754
>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
Length = 1582
Score = 60.5 bits (145), Expect = 6e-09
Identities = 52/222 (23%), Positives = 97/222 (43%), Gaps = 22/222 (9%)
Query: 618 KKQGFSKEIKIP------KTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIK 671
K + ++IK+P +TK ++YE + C+LN + + I K
Sbjct: 416 KYPDYYQQIKMPISLQQIRTKLKN--QEYETLDHLECDLN--LMFENAKRYNVPNSAIYK 471
Query: 672 KLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQ---- 727
++++ +Q K K+ R+ IE + + +G K K ++ +
Sbjct: 472 RVLKLQQVMQAKK-------KELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMK 524
Query: 728 -LYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
L++ + + + FM + + P YY++I PMDLK + ++N Y ++
Sbjct: 525 ILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEE 584
Query: 787 LFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAG 828
+ D++ +F N + YN S+ Y A+ILEK K KE G
Sbjct: 585 GMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELG 626
Score = 60.1 bits (144), Expect = 8e-09
Identities = 28/79 (35%), Positives = 46/79 (58%)
Query: 748 FMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPES 807
F + + + P YY +I+ P+DLKT+++R++N Y S D+ + N K YN P S
Sbjct: 208 FQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGS 267
Query: 808 EYYKCANILEKFFFSKIKE 826
+ +K AN ++K F+ K E
Sbjct: 268 QVFKDANSIKKIFYMKKAE 286
Score = 55.8 bits (133), Expect = 2e-07
Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Query: 727 QLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
+LY+T++ + + F+ KR P YYEV+ P+DL + ++LK Y
Sbjct: 52 ELYNTIRDYKDE-QGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVN 110
Query: 787 LFMADLQRVFTNCKEYNPPESEYYKCA 813
L AD Q +F N K Y P+S YK A
Sbjct: 111 LLTADFQLLFNNAKSYYKPDSPEYKAA 137
Score = 55.8 bits (133), Expect = 2e-07
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 727 QLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKK 786
QLY T++S + A PF + + P YY+ I+ P+ L+ + +LKN+ Y +
Sbjct: 388 QLYDTVRSCRNN-QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLD 446
Query: 787 LFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
DL +F N K YN P S YK L++ +K KE
Sbjct: 447 HLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKE 486
Score = 47.8 bits (112), Expect = 4e-05
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 4/114 (3%)
Query: 707 RETGWKPSGKEKSKEPRDP--DQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVI 764
R++G P K K P +++Y +K+ + SA F+ R+E P YY I
Sbjct: 643 RKSGISPK-KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI-FLRLPSRSELPDYYLTI 700
Query: 765 RFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEK 818
+ PMD++ + + Y + D +F N YN PES YK A +L K
Sbjct: 701 KKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHK 754
>gi|41350212 bromodomain containing 7 [Homo sapiens]
Length = 651
Score = 59.3 bits (142), Expect = 1e-08
Identities = 33/97 (34%), Positives = 50/97 (51%)
Query: 720 KEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKN 779
+E + L L +++Q++ + F PV APGY +I+ PMD TM E++KN
Sbjct: 128 QEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKIKN 187
Query: 780 RYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANIL 816
Y S + + + + TN YN PE+ YYK A L
Sbjct: 188 NDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKL 224
>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
Length = 1058
Score = 58.5 bits (140), Expect = 2e-08
Identities = 28/82 (34%), Positives = 45/82 (54%)
Query: 732 LKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMAD 791
L+S+L Q++ A F +PV E P Y + I+ PMD TM +RL+ + Y + F D
Sbjct: 571 LRSVLDQLQDKDPARIFAQPVSLKEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEED 630
Query: 792 LQRVFTNCKEYNPPESEYYKCA 813
+ NC +YN ++ +Y+ A
Sbjct: 631 FDLIIDNCMKYNARDTVFYRAA 652
>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
Length = 597
Score = 57.4 bits (137), Expect = 5e-08
Identities = 47/168 (27%), Positives = 73/168 (43%), Gaps = 10/168 (5%)
Query: 664 KKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPR 723
+K+KE K+ ER+ G + D +++ +E P + E P
Sbjct: 86 RKRKEEKKRKREREHCDTE----GEADDFDPGKKVEVEPPPDRPVRACRTQPAENESTP- 140
Query: 724 DPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYV 783
+ L+ L+Q++ F PV APGY +I+ PMD TM +++ Y
Sbjct: 141 ----IQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYK 196
Query: 784 SKKLFMADLQRVFTNCKEYNPPESEYYKCA-NILEKFFFSKIKEAGLI 830
S F AD + + N YN P++ YYK A IL F K+A L+
Sbjct: 197 SVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQAALL 244
>gi|34452707 bromodomain containing 8 isoform 2 [Homo sapiens]
Length = 1235
Score = 57.4 bits (137), Expect = 5e-08
Identities = 27/83 (32%), Positives = 44/83 (53%)
Query: 731 TLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMA 790
TL + + + SH+ + PF++PV +APGY +V++ PMDL ++ L + F+
Sbjct: 1111 TLLPVWKMIASHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLR 1170
Query: 791 DLQRVFTNCKEYNPPESEYYKCA 813
DL +F N YN + Y A
Sbjct: 1171 DLMLMFQNAVMYNDSDHHVYHMA 1193
Score = 52.8 bits (125), Expect = 1e-06
Identities = 25/86 (29%), Positives = 47/86 (54%)
Query: 741 SHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCK 800
+H+ A F++PV APGY+ +++ PMDL T+ + ++N S F D+ +F N
Sbjct: 725 NHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAV 784
Query: 801 EYNPPESEYYKCANILEKFFFSKIKE 826
YN + + Y A +++ +I++
Sbjct: 785 MYNSSDHDVYHMAVEMQRDVLEQIQQ 810
>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
sapiens]
Length = 1110
Score = 57.0 bits (136), Expect = 7e-08
Identities = 29/95 (30%), Positives = 54/95 (56%), Gaps = 4/95 (4%)
Query: 735 ILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRY---YVSKKLFMAD 791
+L + H+ + F EPV + P YY++I+ PMDL T+ ++L+ ++ Y F+AD
Sbjct: 969 LLLYLYCHELSIEFQEPVPAS-IPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVAD 1027
Query: 792 LQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKE 826
++ +F NC+ +N +SE + + +F K+ E
Sbjct: 1028 VRLIFKNCERFNEADSEVAQAGKAVALYFEDKLTE 1062
Score = 37.7 bits (86), Expect = 0.044
Identities = 40/142 (28%), Positives = 49/142 (34%), Gaps = 21/142 (14%)
Query: 2 SEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAAA 61
S GG+G AGA A A PP A L + A A GG
Sbjct: 12 SGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGG------------- 58
Query: 62 GTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPP 121
A GP GG A + AQ S+P A GV + + P PS PP
Sbjct: 59 --AAGPDDGGVAAASSGSAQAASSPAAS--VGTGVAGGAVSTPAPAPASAPAPGPSAGPP 114
Query: 122 RADLQQIIVSLTESCRSCSHAL 143
SL ++C C +L
Sbjct: 115 PGP----PASLLDTCAVCQQSL 132
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,167,112
Number of Sequences: 37866
Number of extensions: 1904480
Number of successful extensions: 24675
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 361
Number of HSP's successfully gapped in prelim test: 677
Number of HSP's that attempted gapping in prelim test: 16163
Number of HSP's gapped (non-prelim): 6530
length of query: 832
length of database: 18,247,518
effective HSP length: 111
effective length of query: 721
effective length of database: 14,044,392
effective search space: 10126006632
effective search space used: 10126006632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.