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Search of human proteins with 39930517
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39930517 sterile alpha motif domain containing 1 [Homo
sapiens]
(538 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 1102 0.0
gi|197927257 sterile alpha motif domain containing 13 isoform 2 ... 113 5e-25
gi|197927255 sterile alpha motif domain containing 13 isoform 2 ... 113 5e-25
gi|58293756 sterile alpha motif domain containing 13 isoform 1 [... 113 5e-25
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 106 5e-23
gi|33356148 formin-like 1 [Homo sapiens] 94 2e-19
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 93 7e-19
gi|160707881 formin 2 [Homo sapiens] 90 5e-18
gi|39930375 enabled homolog isoform b [Homo sapiens] 87 4e-17
gi|56549694 enabled homolog isoform a [Homo sapiens] 87 5e-17
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 86 9e-17
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 86 1e-16
gi|163965366 nascent polypeptide-associated complex alpha subuni... 86 1e-16
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 84 3e-16
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 84 3e-16
gi|11386183 WAS protein family, member 2 [Homo sapiens] 84 4e-16
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 83 6e-16
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 82 9e-16
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 82 9e-16
gi|110832843 TBP-associated factor 4 [Homo sapiens] 82 9e-16
gi|47132519 Ras association and pleckstrin homology domains 1 is... 82 9e-16
gi|19924099 synapsin I isoform Ia [Homo sapiens] 82 9e-16
gi|19924097 synapsin I isoform Ib [Homo sapiens] 82 9e-16
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 82 2e-15
gi|153792074 proline rich 12 [Homo sapiens] 82 2e-15
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 81 2e-15
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 80 4e-15
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 79 8e-15
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 79 1e-14
gi|7706501 WW domain binding protein 11 [Homo sapiens] 79 1e-14
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 1102 bits (2850), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MAGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRR 60
MAGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRR
Sbjct: 1 MAGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRR 60
Query: 61 RHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPA 120
RHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPA
Sbjct: 61 RHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPA 120
Query: 121 AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAP 180
AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAP
Sbjct: 121 AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAP 180
Query: 181 PPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAV 240
PPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAV
Sbjct: 181 PPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAV 240
Query: 241 RAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRG 300
RAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRG
Sbjct: 241 RAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRG 300
Query: 301 DRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQ 360
DRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQ
Sbjct: 301 DRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQ 360
Query: 361 HHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVA 420
HHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVA
Sbjct: 361 HHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVA 420
Query: 421 TGPDSPSPVPLPPGKPALPGADGTPFGCPPGRKEKPSDPVEWTVMDVVEYFTEAGFPEQA 480
TGPDSPSPVPLPPGKPALPGADGTPFGCPPGRKEKPSDPVEWTVMDVVEYFTEAGFPEQA
Sbjct: 421 TGPDSPSPVPLPPGKPALPGADGTPFGCPPGRKEKPSDPVEWTVMDVVEYFTEAGFPEQA 480
Query: 481 TAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALKIYEHHIKVLQQGHFEDDDPDGFLG 538
TAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALKIYEHHIKVLQQGHFEDDDPDGFLG
Sbjct: 481 TAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALKIYEHHIKVLQQGHFEDDDPDGFLG 538
>gi|197927257 sterile alpha motif domain containing 13 isoform 2
[Homo sapiens]
Length = 102
Score = 113 bits (282), Expect = 5e-25
Identities = 52/77 (67%), Positives = 62/77 (80%)
Query: 455 KPSDPVEWTVMDVVEYFTEAGFPEQATAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALK 514
+P DP +W VMDVV YF GF EQA+AFQEQEIDGKSLLLM R DVLTGL ++LGPALK
Sbjct: 24 RPPDPADWAVMDVVNYFRTVGFEEQASAFQEQEIDGKSLLLMTRNDVLTGLQLKLGPALK 83
Query: 515 IYEHHIKVLQQGHFEDD 531
IYE+H+K LQ H +++
Sbjct: 84 IYEYHVKPLQTKHLKNN 100
>gi|197927255 sterile alpha motif domain containing 13 isoform 2
[Homo sapiens]
Length = 102
Score = 113 bits (282), Expect = 5e-25
Identities = 52/77 (67%), Positives = 62/77 (80%)
Query: 455 KPSDPVEWTVMDVVEYFTEAGFPEQATAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALK 514
+P DP +W VMDVV YF GF EQA+AFQEQEIDGKSLLLM R DVLTGL ++LGPALK
Sbjct: 24 RPPDPADWAVMDVVNYFRTVGFEEQASAFQEQEIDGKSLLLMTRNDVLTGLQLKLGPALK 83
Query: 515 IYEHHIKVLQQGHFEDD 531
IYE+H+K LQ H +++
Sbjct: 84 IYEYHVKPLQTKHLKNN 100
>gi|58293756 sterile alpha motif domain containing 13 isoform 1
[Homo sapiens]
Length = 116
Score = 113 bits (282), Expect = 5e-25
Identities = 52/77 (67%), Positives = 62/77 (80%)
Query: 455 KPSDPVEWTVMDVVEYFTEAGFPEQATAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALK 514
+P DP +W VMDVV YF GF EQA+AFQEQEIDGKSLLLM R DVLTGL ++LGPALK
Sbjct: 38 RPPDPADWAVMDVVNYFRTVGFEEQASAFQEQEIDGKSLLLMTRNDVLTGLQLKLGPALK 97
Query: 515 IYEHHIKVLQQGHFEDD 531
IYE+H+K LQ H +++
Sbjct: 98 IYEYHVKPLQTKHLKNN 114
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 106 bits (265), Expect = 5e-23
Identities = 80/260 (30%), Positives = 103/260 (39%), Gaps = 35/260 (13%)
Query: 94 RNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAA 153
R A PP RG PP PP PP PPPPPA A P P +
Sbjct: 274 RQAPPPPPPSRGGPPPPPP--------------PPHNSGPPPPPARGRGAPP---PPPSR 316
Query: 154 AAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP 213
A APP P P++P P PP P A P+ AP P PPP+V P PP
Sbjct: 317 APTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPP--PPPPSVLGVGPVAPP 374
Query: 214 PPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRV 273
PP PP PP PPP P P +G A +L + +R G +L +
Sbjct: 375 PPPPPPPP---PGPPPPPGLPSDGDHQVPTTAGNKAALLDQIR-------EGAQLKKVEQ 424
Query: 274 QGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEE-- 331
+ L++ R G D PP + P+ G V++K +
Sbjct: 425 NSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPA--PTSGIVGALMEVMQKRSKAI 482
Query: 332 --EDDDEDEDEEDDVSEGSE 349
D+DEDED+E+D + E
Sbjct: 483 HSSDEDEDEDDEEDFEDDDE 502
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 94.4 bits (233), Expect = 2e-19
Identities = 73/222 (32%), Positives = 90/222 (40%), Gaps = 36/222 (16%)
Query: 52 ERICRMVRRRHGPEPERTR--AELEKLIQQ--RAVLRVSYKGSISYRNAARVQPPRRGAT 107
E++ + R E E AELEK + Q + + + + S S A +PP
Sbjct: 406 EQVALLTERLRDAENESMAKIAELEKQLSQARKELETLRERFSESTAMGASRRPPEPEKA 465
Query: 108 PPAPPRAP-------------------RGAPAAAA------AAAPPPTPAPPPPPAPVAA 142
PPA P P RG A + A A P P P P +
Sbjct: 466 PPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGS 525
Query: 143 AAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPP 202
+P AP A A APP P P PG + + AP +APP AP P + PP P P
Sbjct: 526 PSPDLAPAAEPAPGAAPPPPPPL-PGLPSPQEAPPSAPPQAPPLPGSPEPP------PAP 578
Query: 203 AVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGG 244
+ PP PPPP PP PPPP P PPP GG A G
Sbjct: 579 PLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALG 620
Score = 72.4 bits (176), Expect = 1e-12
Identities = 65/208 (31%), Positives = 86/208 (41%), Gaps = 36/208 (17%)
Query: 46 KARPDLERI-------CRMVRRRHGPEPER------TRAELEKL----IQQRAVLRVSYK 88
+AR +LE + M R PEPE+ TR +L ++++ ++R+ +
Sbjct: 435 QARKELETLRERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRI-LR 493
Query: 89 G-----SISYRNAARVQPPRRGA-TPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAA 142
G SI A P A TP P +P +P A AA P P APPPPP
Sbjct: 494 GPGDAVSIEILPVAVATPSGGDAPTPGVPTGSP--SPDLAPAAEPAPGAAPPPPPPLPGL 551
Query: 143 AAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAV--------APPA 194
+P AP +A APP PG +P P L PPP P PP PP
Sbjct: 552 PSPQEAP--PSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPP 609
Query: 195 GPRRAPPPAVAAREPPLPPPPQPPAPPQ 222
P PP A+ R+ L P + P Q
Sbjct: 610 PPPGGPPDALGRRDSELGPGVKAKKPIQ 637
Score = 37.0 bits (84), Expect = 0.046
Identities = 38/131 (29%), Positives = 43/131 (32%), Gaps = 16/131 (12%)
Query: 121 AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAP 180
A A+ PP P PP AP +A GP
Sbjct: 452 AMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDA------------- 498
Query: 181 PPAPAAPPAVAPPAGPRRAPPPAVAAREP-PLPPPPQPPAPPQQQQPPPPQP-QPPPEGG 238
P AVA P+G AP P V P P P PAP PPPP P P P+
Sbjct: 499 VSIEILPVAVATPSGGD-APTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEA 557
Query: 239 AVRAGGAARPV 249
A A P+
Sbjct: 558 PPSAPPQAPPL 568
Score = 32.3 bits (72), Expect = 1.1
Identities = 37/148 (25%), Positives = 51/148 (34%), Gaps = 18/148 (12%)
Query: 326 LEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGP 385
LEK+ + E E + SE + + S RP + P + + +V+E G
Sbjct: 429 LEKQLSQARKELETLRERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGL 488
Query: 386 HQGQDEGRGPAPGSGTRQVFSMAAMNKEGG---TASVATGPDSPSPVPL----------- 431
+ RGP ++ +A GG T V TG SP P
Sbjct: 489 IRIL---RGPGDAVSI-EILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPP 544
Query: 432 PPGKPALPGADGTPFGCPPGRKEKPSDP 459
PP P LP P PP P P
Sbjct: 545 PPPLPGLPSPQEAPPSAPPQAPPLPGSP 572
Score = 32.3 bits (72), Expect = 1.1
Identities = 49/181 (27%), Positives = 59/181 (32%), Gaps = 26/181 (14%)
Query: 288 ERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEE-------RVLEKEEEEDDDEDEDE 340
E T +GA P P +APPAA RPS + EE R+L + E
Sbjct: 449 ESTAMGASRRP--PEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPV 506
Query: 341 EDDVSEGSEVPESDRPAGAQHHQL--NGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPG 398
G + P P G+ L E P +A P P G + AP
Sbjct: 507 AVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAP------PPPPPLPGLPSPQ-EAPP 559
Query: 399 SGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPALPGADGTPFGCPPGRKEKPSD 458
S Q + S P P P LPP P P GT PP P
Sbjct: 560 SAPPQAPPL--------PGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPP 611
Query: 459 P 459
P
Sbjct: 612 P 612
Score = 30.8 bits (68), Expect = 3.3
Identities = 15/31 (48%), Positives = 15/31 (48%)
Query: 121 AAAAAAPPPTPAPPPPPAPVAAAAPARAPRA 151
A AA PP PAPP P P A R RA
Sbjct: 12 AGPAAPPPKQPAPPKQPMPAAGELEERFNRA 42
Score = 29.6 bits (65), Expect = 7.3
Identities = 13/26 (50%), Positives = 17/26 (65%), Gaps = 2/26 (7%)
Query: 203 AVAAREP--PLPPPPQPPAPPQQQQP 226
A +A +P P PPP+ PAPP+Q P
Sbjct: 5 AGSAEQPAGPAAPPPKQPAPPKQPMP 30
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 92.8 bits (229), Expect = 7e-19
Identities = 96/369 (26%), Positives = 129/369 (34%), Gaps = 52/369 (14%)
Query: 101 PPRRGATP---PAPPRAPRGAPAAAA--AAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA 155
PP+ G P P+PP P+G P PPP P P P P P
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ--------- 90
Query: 156 ATAPPSPG-PAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPP 214
PP PG P P P+ ++ +PP P PP P G + PP PPP
Sbjct: 91 --GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPP---------PPP 136
Query: 215 PQPPAPPQQ-----QQPPPP-QPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRL 268
+P PP Q Q PPPP +PQ PP G ++ + P + GG+ G
Sbjct: 137 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP 196
Query: 269 TRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEK 328
G+ QG +G + P+G P + SAR K G
Sbjct: 197 PPGKPQG-----PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251
Query: 329 EEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCG-PHQ 387
+ + + +G P+ P G + G +S R P G P Q
Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-PPQGGSKSRSSRSPPGKPQGPPPQ 310
Query: 388 GQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPALPGADGTPFG 447
G ++ +GP P G Q G P P P P G P G+
Sbjct: 311 GGNQPQGPPPPPGKPQ----------GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR 360
Query: 448 CPPGRKEKP 456
PPG+ + P
Sbjct: 361 SPPGKPQGP 369
Score = 85.5 bits (210), Expect = 1e-16
Identities = 98/383 (25%), Positives = 131/383 (34%), Gaps = 74/383 (19%)
Query: 101 PPRRGATP--PAPPRAPRGAP----AAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAA 154
PP+ G P P PP P+G P + + +PP P PPP P
Sbjct: 82 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP--------- 132
Query: 155 AATAPPSPGPAQPGPRAQRAAPLAAPPPA-PAAPP---------AVAPPAGPRRAPPPAV 204
PP PG Q P P PPP P PP + +PP P+ PP
Sbjct: 133 ----PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG 188
Query: 205 AAREPPLPPPPQPPAPPQQ-----QQPPPP-QPQPPPEGGAVRAGGAARPVSLREVVRYL 258
+ P PPP +P PP Q Q PPPP +PQ PP G ++ A P +
Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQ 248
Query: 259 GGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSK 318
GG+ G G+ QG P+G + PP
Sbjct: 249 GGNQPQGPPPPPGKPQG--------------------PPPQGGNKPQGPPPPGKPQGPPP 288
Query: 319 RGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVK 378
+GG + + + + +G P +P G N +GP
Sbjct: 289 QGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGP-------- 339
Query: 379 EWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDS-PSPVPLPPGKPA 437
P G+ +G P GS +R S +G P P P P +P
Sbjct: 340 ------PPPGKPQGPPPQGGSKSRSARSPPG-KPQGPPQQEGNNPQGPPPPAGGNPQQPQ 392
Query: 438 LPGADGTPFGCP-PGRKEKPSDP 459
P A G P G P P + +PS P
Sbjct: 393 APPA-GQPQGPPRPPQGGRPSRP 414
Score = 83.6 bits (205), Expect = 4e-16
Identities = 88/347 (25%), Positives = 118/347 (34%), Gaps = 40/347 (11%)
Query: 128 PPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP-GPRAQRAAPLAAPPPAPAA 186
P A P AP + P + PP G QP GP P PP
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88
Query: 187 PPAVAPPAGPRRAPPPAVAAREP------PLPPPPQPPAPPQQQQPPPPQPQ-PPPEGGA 239
P PP P+ PP +R P P PPPQ PQ PPP +PQ PPP+GG
Sbjct: 89 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 148
Query: 240 VRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPR 299
G P + G + R G+ QG P+
Sbjct: 149 KPQG--PPPPGKPQGPPPQGDNKSRSSRSPPGKPQG--------------------PPPQ 186
Query: 300 GDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGA 359
G + PP +P G + + D+ S+ + P +P G
Sbjct: 187 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPG-KPQGP 245
Query: 360 QHHQLNGERGPQSAKERVKEWTPCGPHQGQ-----DEGRGPAPGSGTRQVFSMAAMNKEG 414
N +GP + + P G ++ Q + +GP P G++ S + K
Sbjct: 246 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQ 305
Query: 415 GTASVATGPDSPSPVPLPPGKPALPGADG--TPFGCPPGRKEKPSDP 459
G G + P P PPGKP P G P G PP K + P
Sbjct: 306 GPP--PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 350
Score = 64.7 bits (156), Expect = 2e-10
Identities = 49/150 (32%), Positives = 60/150 (40%), Gaps = 20/150 (13%)
Query: 101 PPRRGATP--PAPPRAPRGAPA-----AAAAAAPPPTPAPPPPPA-------PVAAAAPA 146
PP+ G P P PP P+G P + ++ +PP P PPP P P
Sbjct: 267 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 326
Query: 147 RAPRAAAAAATAPPSPG-PAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVA 205
P PP PG P P P+ + A PP P P+ PPPA
Sbjct: 327 GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGG 386
Query: 206 AREPPLPPP---PQ-PPAPPQQQQPP-PPQ 230
+ P PP PQ PP PPQ +P PPQ
Sbjct: 387 NPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 90.1 bits (222), Expect = 5e-18
Identities = 63/161 (39%), Positives = 64/161 (39%), Gaps = 23/161 (14%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP----PPPPAPVAAAAPARAPRAA 152
PP GA P PP P P A PPP P P PPPP A P P
Sbjct: 957 PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1016
Query: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA---PPAVAPPAGPRRAPPPAVAAREP 209
A PP PG P P A + PPP P A PP P AG PPP A P
Sbjct: 1017 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIP 1075
Query: 210 PLPP------PPQPPAPPQQQQPPPPQ-----PQPPPEGGA 239
P PP PP PP P PPPP P PPP GA
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA 1116
Score = 89.7 bits (221), Expect = 6e-18
Identities = 63/156 (40%), Positives = 64/156 (41%), Gaps = 24/156 (15%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPA---PPPPPAPVAAAAPARAPRAAAAAAT 157
PP GA P PP P A PPP P PPPPP P A P P A
Sbjct: 946 PPLPGAAIPPPPPLP-----GAGIPLPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAGIPP 999
Query: 158 APPSPGPAQPGPRAQRAAPLAAPPPAPAA---PPAVAPPAGPRRAPPPAVAAREPPLPP- 213
PP PG P P A + PPP P A PP P AG PPP A PP PP
Sbjct: 1000 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPL 1058
Query: 214 -----PPQPPAPPQQQQPPPPQ-----PQPPPEGGA 239
PP PP P PPPP P PPP GA
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1094
Score = 89.7 bits (221), Expect = 6e-18
Identities = 63/161 (39%), Positives = 64/161 (39%), Gaps = 23/161 (14%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP----PPPPAPVAAAAPARAPRAA 152
PP GA P PP P P A PPP P P PPPP A P P
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1027
Query: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA---PPAVAPPAGPRRAPPPAVAAREP 209
A PP PG P P A + PPP P A PP P AG PPP A P
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIP 1086
Query: 210 PLPP------PPQPPAPPQQQQPPPPQ-----PQPPPEGGA 239
P PP PP PP P PPPP P PPP GA
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGA 1127
Score = 89.7 bits (221), Expect = 6e-18
Identities = 62/161 (38%), Positives = 63/161 (39%), Gaps = 23/161 (14%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP-----PPPPAPVAAAAPARAPRA 151
PP GA P PP P P A PPP P P PPPP P A P P
Sbjct: 979 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLP 1037
Query: 152 AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA--PPAVAPPAGPRRAPPPAVAAREP 209
A PP PG P P A + PPP P A PP P PPP A P
Sbjct: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1097
Query: 210 PLPP------PPQPPAPPQQQQPPPPQ-----PQPPPEGGA 239
P PP PP PP P PPPP P PPP GA
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1138
Score = 89.7 bits (221), Expect = 6e-18
Identities = 61/160 (38%), Positives = 63/160 (39%), Gaps = 21/160 (13%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP----PPPPAPVAAAAPARAPRAA 152
PP GA P PP P P A PPP P P PPPP A P P
Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1060
Query: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA--PPAVAPPAGPRRAPPPAVAAREPP 210
A PP PG P P A + PPP P A PP P PPP A PP
Sbjct: 1061 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120
Query: 211 LPP------PPQPPAPPQQQQPPPPQPQ-----PPPEGGA 239
PP PP PP P PPPP P+ PPP GA
Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA 1160
Score = 88.2 bits (217), Expect = 2e-17
Identities = 62/161 (38%), Positives = 63/161 (39%), Gaps = 23/161 (14%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP----PPPPAPVAAAAPARAPRAA 152
PP GA P PP P P A PPP P P PPPP A P P
Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1071
Query: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA---PPAVAPPAGPRRAPPPAVAAREP 209
A PP PG P P A + PPP P PP P AG PPP A P
Sbjct: 1072 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIP-PPPPLPGAGIP 1130
Query: 210 PLPP------PPQPPAPPQQQQPPPPQ-----PQPPPEGGA 239
P PP PP PP P PPPP P PPP GA
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGA 1171
Score = 87.4 bits (215), Expect = 3e-17
Identities = 61/163 (37%), Positives = 63/163 (38%), Gaps = 24/163 (14%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP----PPPPAPVAAAAPARAPRAA 152
PP GA P PP P P A PPP P P PPPP A P P
Sbjct: 913 PPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPG 972
Query: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA---PPAVAPPAGPRRAPPPAVAAREP 209
A PP PG P P A + PPP P A PP P AG PPP A P
Sbjct: 973 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIP 1031
Query: 210 PLPP------PPQPPAPPQQQQPPPP------QPQPPPEGGAV 240
P PP PP PP P PPPP P PP G +
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1074
Score = 87.0 bits (214), Expect = 4e-17
Identities = 60/155 (38%), Positives = 61/155 (39%), Gaps = 21/155 (13%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP----PPPPAPVAAAAPARAPRAA 152
PP GA P PP P P A PPP P P PPPP A P P
Sbjct: 990 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049
Query: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA---PPAVAPPAGPRRAPPPAVAAREP 209
A PP PG P P A + PPP P A PP P AG PPP P
Sbjct: 1050 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGVGIP 1108
Query: 210 PLPP------PPQPPAPPQQQQPPPPQPQ---PPP 235
P PP PP PP P PPPP P PPP
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1143
Score = 87.0 bits (214), Expect = 4e-17
Identities = 60/155 (38%), Positives = 61/155 (39%), Gaps = 21/155 (13%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP----PPPPAPVAAAAPARAPRAA 152
PP GA P PP P P A PPP P P PPPP A P P
Sbjct: 1023 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1082
Query: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA---PPAVAPPAGPRRAPPPAVAAREP 209
A PP PG P P + PPP P A PP P AG PPP A P
Sbjct: 1083 AGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIP 1141
Query: 210 PLPP------PPQPPAPPQQQQPPPPQPQ---PPP 235
P PP PP PP P PPPP P PPP
Sbjct: 1142 PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1176
Score = 87.0 bits (214), Expect = 4e-17
Identities = 66/172 (38%), Positives = 67/172 (38%), Gaps = 34/172 (19%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP-----PPPPAPVAAAAPARAPRA 151
PP GA P PP P P A PPP P P PPPP P A P P
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLP 1092
Query: 152 AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA---PPAVAPPAG-------PR---R 198
A PP PG P P A + PPP P A PP P AG PR
Sbjct: 1093 GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIP 1152
Query: 199 APPPAVAAREPPLPP------PPQPPAPPQQQQPPPPQ-----PQPPPEGGA 239
PPP A PP PP PP PP P PPPP P PPP GA
Sbjct: 1153 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGA 1204
Score = 86.7 bits (213), Expect = 5e-17
Identities = 63/156 (40%), Positives = 64/156 (41%), Gaps = 24/156 (15%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPA---PPPPPAPVAAAAPARAPRAAAAAAT 157
PP GA P PP P AA PPP P P PPP P A P P A
Sbjct: 935 PPLPGAGIPPPPPLP-----GAAIPPPPPLPGAGIPLPPPLP-GAGIPPPPPLPGAGIPP 988
Query: 158 APPSPGPAQPGPRAQRAAPLAAPPPAPAA---PPAVAPPAGPRRAPPPAVAAREPPLPP- 213
PP PG P P A + PPP P A PP P AG PPP A PP PP
Sbjct: 989 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPL 1047
Query: 214 -----PPQPPAPPQQQQPPPPQ-----PQPPPEGGA 239
PP PP P PPPP P PPP GA
Sbjct: 1048 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1083
Score = 84.7 bits (208), Expect = 2e-16
Identities = 61/163 (37%), Positives = 64/163 (39%), Gaps = 25/163 (15%)
Query: 101 PPRRGATPPAPPRA--PRGAPAAAAAAAPPPTPA------PPPPPAPVAAAAPARAPRAA 152
PP G T P P P+ P PPP P PPPPP P A P P
Sbjct: 881 PPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPL-PPLPG 939
Query: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA---PPAVAPPAGPRRAPPPAVAAREP 209
A PP PG A P P A + PPP P A PP P AG PPP A P
Sbjct: 940 AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIP 998
Query: 210 PLPP------PPQPPAPPQQQQPPPP------QPQPPPEGGAV 240
P PP PP PP P PPPP P PP G +
Sbjct: 999 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1041
Score = 84.3 bits (207), Expect = 2e-16
Identities = 58/155 (37%), Positives = 59/155 (38%), Gaps = 21/155 (13%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP-----PPPPAPVAAAAPARAPRA 151
PP GA P PP P P A PPP P P PPPP P P P
Sbjct: 1056 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GVGIPPPPPLP 1114
Query: 152 AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAP--AAPPAVAPPAGPRRAPPPAVAAREP 209
A PP PG P P A + PPP P PP P PPP A P
Sbjct: 1115 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP 1174
Query: 210 PLPP------PPQPPAPPQQQQPPPPQPQ---PPP 235
P PP PP PP P PPPP P PPP
Sbjct: 1175 PPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPP 1209
Score = 83.2 bits (204), Expect = 6e-16
Identities = 56/148 (37%), Positives = 57/148 (38%), Gaps = 18/148 (12%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP----PPPPAPVAAAAPARAPRAA 152
PP GA P PP P P A PPP P P PPPP A P P
Sbjct: 1067 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG 1126
Query: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA---PPAVAPPAGPRRAPPPAVAAREP 209
A PP PG P P + PPP P A PP P AG PPP P
Sbjct: 1127 AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGVGIP 1185
Query: 210 PLPP------PPQPPAPPQQQQPPPPQP 231
P PP PP PP P PPPP P
Sbjct: 1186 PPPPLPGVGIPPPPPLPGAGIPPPPPLP 1213
Score = 81.3 bits (199), Expect = 2e-15
Identities = 56/155 (36%), Positives = 57/155 (36%), Gaps = 18/155 (11%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP-----PPPPAPVAAAAPARAPRA 151
PP GA P PP P P PPP P P PPPP P A P P
Sbjct: 1078 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLP 1136
Query: 152 AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA--PPAVAPPAGPRRAPPPAVAAREP 209
A PP P P P A + PPP P A PP P PPP P
Sbjct: 1137 GAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIP 1196
Query: 210 PLPP------PPQPPAPPQQQQPPPPQPQPPPEGG 238
P PP PP PP P P P P PPP G
Sbjct: 1197 PPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTG 1231
Score = 79.7 bits (195), Expect = 6e-15
Identities = 57/157 (36%), Positives = 59/157 (37%), Gaps = 23/157 (14%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP-----PPPPAPVAAAAPARAPRA 151
PP GA P PP P P A PPP P P PPPP P A P P
Sbjct: 1111 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP-GAGIPPPPPLP 1169
Query: 152 AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA----PPAV----APPAGPRRAPPPA 203
A PP PG P P + PPP P A PP + PPA PPP
Sbjct: 1170 GAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPG 1229
Query: 204 VAAREPPLPPPPQPPAPPQQQQPPPPQPQ-----PPP 235
PPL P PP PQ P PQ PPP
Sbjct: 1230 TGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP 1266
Score = 78.2 bits (191), Expect = 2e-14
Identities = 54/148 (36%), Positives = 55/148 (37%), Gaps = 13/148 (8%)
Query: 101 PPRRGATPPAPPRAPRGA----PAAAAAAAPPPTPAP----PPPPAPVAAAAPARAPRAA 152
PP GA P PP P P A PPP P P PPPP A P P
Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPR 1148
Query: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAA--PPAVAPPAGPRRAPPPAVAAREPP 210
PP PG P P A + PPP P PP P PPP A PP
Sbjct: 1149 VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPP 1208
Query: 211 LPPPPQ---PPAPPQQQQPPPPQPQPPP 235
PP P PPAP PP PPP
Sbjct: 1209 PPPLPGMGIPPAPAPPLPPPGTGIPPPP 1236
Score = 77.8 bits (190), Expect = 2e-14
Identities = 56/156 (35%), Positives = 59/156 (37%), Gaps = 27/156 (17%)
Query: 102 PRRGATPPAPPRAP-RGAPAAAAAAAPPPTPA---------PPPPPAPVAAAAPARAPRA 151
P G PP PP P P + A P P P PPP P A P P
Sbjct: 871 PGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP---GAGIPPPPPLP 927
Query: 152 AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPL 211
A PP PG P P A + PPP P A + PP PPP PPL
Sbjct: 928 GAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP------PPL 981
Query: 212 PP---PPQPPAPPQQQQPPPPQ-----PQPPPEGGA 239
P PP PP P PPPP P PPP GA
Sbjct: 982 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1017
Score = 47.4 bits (111), Expect = 3e-05
Identities = 35/132 (26%), Positives = 47/132 (35%), Gaps = 6/132 (4%)
Query: 100 QPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP 159
QP + + PP PP +A P PP + + + +A +
Sbjct: 802 QPTQSISQPPPPPSL------LWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNI 855
Query: 160 PSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPA 219
PSP P + L PP P P + P P A P + + PPP PP
Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
Query: 220 PPQQQQPPPPQP 231
P PPPP P
Sbjct: 916 PGAGIPPPPPLP 927
Score = 41.2 bits (95), Expect = 0.002
Identities = 40/137 (29%), Positives = 48/137 (35%), Gaps = 12/137 (8%)
Query: 102 PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPS 161
PR PP +P G P + A + P PA P+ A P P AA A P
Sbjct: 287 PREPQQPP----SPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGA---PV 339
Query: 162 PGPAQPGPRAQRAAPLAAPPPAPAA--PPAVAPPAGPRRAPPPAVAAREPPLPPP---PQ 216
G + A AP +P P V A R P A+ P P P
Sbjct: 340 RGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPG 399
Query: 217 PPAPPQQQQPPPPQPQP 233
PAP Q+ P P P
Sbjct: 400 SPAPSQRCFKPYPLITP 416
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/197 (22%), Positives = 69/197 (35%), Gaps = 23/197 (11%)
Query: 67 ERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRG--ATPPAPPRAPRG------- 117
E R E +++ R + S + S + PP G PP PP A G
Sbjct: 724 EALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCS 783
Query: 118 ------APAAAAAAAPPPTPA-----PPPPPAPVAAAAPAR-APRAAAAAATAPPSPGPA 165
+P + P PPPPP+ + +A + + + +T +
Sbjct: 784 EISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEH 843
Query: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPA-GPRRAPPPAVAARE-PPLPPPPQPPAPPQQ 223
+ + + +PPP P + + P G PPP + P LP P PP Q
Sbjct: 844 SVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQ 903
Query: 224 QQPPPPQPQPPPEGGAV 240
P P PP G +
Sbjct: 904 GTEMLPPPPPPLPGAGI 920
Score = 40.4 bits (93), Expect = 0.004
Identities = 63/244 (25%), Positives = 80/244 (32%), Gaps = 39/244 (15%)
Query: 100 QPPRRGATPPAP-PRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR----------- 147
QPP G P + P P PAA + + P P P AA AP R
Sbjct: 292 QPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEE 351
Query: 148 -----APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRA--- 199
APR + A P G P + A P APAA PA +R
Sbjct: 352 DAFEDAPRGSPGEEWA-PEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKP 410
Query: 200 ----PPPAVAAREPPLPPPPQPPAPPQQQQPP-PPQPQPPPEGGAVRAGGAARPVSLREV 254
P + L P P+ Q P +P+P ++ G S+
Sbjct: 411 YPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEP-----SLSRGSRTALASVAAP 465
Query: 255 VRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRG---DRPGRAPPAAS 311
+ GG L+R EE A R R A L RG D G PA +
Sbjct: 466 AKKHRADGGLAAGLSRS--ADWTEELGA---RTPRVGGSAHLLERGVASDSGGGVSPALA 520
Query: 312 ARPS 315
A+ S
Sbjct: 521 AKAS 524
Score = 31.6 bits (70), Expect = 1.9
Identities = 34/118 (28%), Positives = 39/118 (33%), Gaps = 18/118 (15%)
Query: 122 AAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP-GPRAQRAAPLAAP 180
A A PPT P P A + P + A AP SP Q + LAA
Sbjct: 229 AEEPAAPPTAVSPQPGAFLGLDRFLLGP--SGGAGEAPGSPDTEQALSALSDLPESLAAE 286
Query: 181 PPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGG 238
P P PP+ P G P P P A P + P P PE G
Sbjct: 287 PREPQQPPS---PGGL------------PVSEAPSLPAAQPAAKDSPSSTAFPFPEAG 329
Score = 31.6 bits (70), Expect = 1.9
Identities = 22/71 (30%), Positives = 25/71 (35%), Gaps = 10/71 (14%)
Query: 101 PPRRGA-TPPAPPRAPRGAPAAAAAAAPPP---------TPAPPPPPAPVAAAAPARAPR 150
PP GA PP PP G P A A PPP P PP P ++ P+
Sbjct: 1199 PPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQ 1258
Query: 151 AAAAAATAPPS 161
PS
Sbjct: 1259 VCGFLPPPLPS 1269
Score = 30.8 bits (68), Expect = 3.3
Identities = 49/170 (28%), Positives = 62/170 (36%), Gaps = 18/170 (10%)
Query: 223 QQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYL-GGSGGAGGRL----TRGRVQGL- 276
QQQ Q Q E A + +P + + R+L G SGGAG T + L
Sbjct: 218 QQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALS 277
Query: 277 -LEEEAAARGRLERTRLGALALPRGDRPG--RAPPAASARPSRSK------RGGEERVLE 327
L E AA R + LP + P A PAA PS + GEE
Sbjct: 278 DLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGA 337
Query: 328 KEEEEDDDEDEDEED---DVSEGSEVPESDRPAGAQHHQLNGERGPQSAK 374
D ++E EED D GS E G Q GE + A+
Sbjct: 338 PVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQ 387
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 87.0 bits (214), Expect = 4e-17
Identities = 92/353 (26%), Positives = 131/353 (37%), Gaps = 48/353 (13%)
Query: 51 LERICRMVRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPA 110
LER R+ R R + LE+ Q+R + + + R+ A PA
Sbjct: 216 LERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRIS----SAAAPA 271
Query: 111 PPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAP--RAAAAAATAPPSPGPAQPG 168
P + ++A+ P A A+ PA P + APP P P PG
Sbjct: 272 SVETPLNSVLGDSSASEPGLQA---------ASQPAETPSQQGIVLGPLAPPPPPPLPPG 322
Query: 169 PRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPP 228
P A +A PPP P PP PP P PPP PPP PP P Q PPP
Sbjct: 323 PAQ---ASVALPPP-PGPPP---PPPLPSTGPPP----------PPPPPPLPNQVPPPPP 365
Query: 229 PQPQPP-PEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRL 287
P P PP P G A S+ E R L G A +V + + + G
Sbjct: 366 PPPAPPLPASGFFLA-------SMSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNA 418
Query: 288 ERTRLGALALPRGDRPGRAP-------PAASARPSRSKRGGEE-RVLEKEEEEDDDEDED 339
+ G G P SA +R +R E+ +E E++ED ED +
Sbjct: 419 IGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDKGEDSE 478
Query: 340 EEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEG 392
+ + PE R + + +NG + P ++ + + + Q EG
Sbjct: 479 PVTSKASSTSTPEPTRKPWERTNTMNGSKSPVISRPKSTPLSQPSANGVQTEG 531
Score = 43.5 bits (101), Expect = 5e-04
Identities = 60/190 (31%), Positives = 77/190 (40%), Gaps = 17/190 (8%)
Query: 267 RLTRGRVQG-LLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERV 325
RL R R++ LE E R RLER RL L R +R R R R +R +ER
Sbjct: 160 RLERERMERERLERERLERERLERERLEQEQLER-ERQERERQERLERQERLER--QER- 215
Query: 326 LEKEEEEDDDEDEDEEDDVSEG--SEVPESDRPAGAQHHQLNGERGPQ--SAKERVKEWT 381
LE++E D + E +E + E E E +R + QL ER + SA T
Sbjct: 216 LERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVET 275
Query: 382 PCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDS-PSPVPLPPGKPALPG 440
P G P G + A + G + GP + P P PLPPG
Sbjct: 276 PLNSVLGDSSASEP----GLQAASQPAETPSQQG---IVLGPLAPPPPPPLPPGPAQASV 328
Query: 441 ADGTPFGCPP 450
A P G PP
Sbjct: 329 ALPPPPGPPP 338
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 86.7 bits (213), Expect = 5e-17
Identities = 89/331 (26%), Positives = 123/331 (37%), Gaps = 48/331 (14%)
Query: 51 LERICRMVRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPA 110
LER R+ R R + LE+ Q+R + + + R+ A PA
Sbjct: 216 LERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRIS----SAAAPA 271
Query: 111 PPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAP--RAAAAAATAPPSPGPAQPG 168
P + ++A+ P A A+ PA P + APP P P PG
Sbjct: 272 SVETPLNSVLGDSSASEPGLQA---------ASQPAETPSQQGIVLGPLAPPPPPPLPPG 322
Query: 169 PRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPP 228
P A +A PPP P PP PP P PPP PPP PP P Q PPP
Sbjct: 323 PAQ---ASVALPPP-PGPPP---PPPLPSTGPPP----------PPPPPPLPNQVPPPPP 365
Query: 229 PQPQPP-PEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRL 287
P P PP P G A S+ E R L G A +V + + + G
Sbjct: 366 PPPAPPLPASGFFLA-------SMSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNA 418
Query: 288 ERTRLGALALPRGDRPGRAP-------PAASARPSRSKRGGEE-RVLEKEEEEDDDEDED 339
+ G G P SA +R +R E+ +E E++ED ED +
Sbjct: 419 IGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDKGEDSE 478
Query: 340 EEDDVSEGSEVPESDRPAGAQHHQLNGERGP 370
+ + PE R + + +NG + P
Sbjct: 479 PVTSKASSTSTPEPTRKPWERTNTMNGSKSP 509
Score = 43.5 bits (101), Expect = 5e-04
Identities = 60/190 (31%), Positives = 77/190 (40%), Gaps = 17/190 (8%)
Query: 267 RLTRGRVQG-LLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERV 325
RL R R++ LE E R RLER RL L R +R R R R +R +ER
Sbjct: 160 RLERERMERERLERERLERERLERERLEQEQLER-ERQERERQERLERQERLER--QER- 215
Query: 326 LEKEEEEDDDEDEDEEDDVSEG--SEVPESDRPAGAQHHQLNGERGPQ--SAKERVKEWT 381
LE++E D + E +E + E E E +R + QL ER + SA T
Sbjct: 216 LERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSAAAPASVET 275
Query: 382 PCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDS-PSPVPLPPGKPALPG 440
P G P G + A + G + GP + P P PLPPG
Sbjct: 276 PLNSVLGDSSASEP----GLQAASQPAETPSQQG---IVLGPLAPPPPPPLPPGPAQASV 328
Query: 441 ADGTPFGCPP 450
A P G PP
Sbjct: 329 ALPPPPGPPP 338
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 85.9 bits (211), Expect = 9e-17
Identities = 113/409 (27%), Positives = 136/409 (33%), Gaps = 96/409 (23%)
Query: 102 PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPS 161
P GA P P RG P P P P PPPP AP AA P A A+ + S
Sbjct: 764 PLMGAAAPQYPG--RGPP-------PAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSS 814
Query: 162 PGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPP 221
PGP +PG P P A P AA E +P P PP PP
Sbjct: 815 PGP-KPGDSGYE----------------TETPFSPEGAFPGGGAAEEEGVPRPRAPPEPP 857
Query: 222 QQQQP-PPPQPQPPPEGG-------AVRAGGAARPVSLRE-VVRYLGGSGGAGGRLT--- 269
P PPP P P P G V+ +SLRE V R L G GA R T
Sbjct: 858 DPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPR 917
Query: 270 --------RGRVQGLLEEEAAARGRLERTRL-----GALALPRGDRPGRAPPAASARPSR 316
R +V GL + + L G L GD+ RAP
Sbjct: 918 KAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQ--RAPGIEEKAAEN 975
Query: 317 SKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKER 376
G ER EK E + E+ E E+ P + +NG P ++++
Sbjct: 976 GALGSPERE-EKVLENGELTPPRREEKALENGELRS---PEAGEKVLVNGGLTPPKSEDK 1031
Query: 377 VKE------------------WTPCGPHQGQDEGRGPAPGSG--------TRQVFSMAAM 410
V E W GP + E GPAP G R A +
Sbjct: 1032 VSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVV 1091
Query: 411 NKEGGTASVATGPDSPSP------------VPLPPGKPALPGADGTPFG 447
+ G A GP P+P P G P PGA G
Sbjct: 1092 SSRNG-GETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLG 1139
Score = 74.7 bits (182), Expect = 2e-13
Identities = 132/494 (26%), Positives = 169/494 (34%), Gaps = 101/494 (20%)
Query: 20 AAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPERTRAELEKLIQQ 79
AA + + SP +E +L+ + R+ LE PE L
Sbjct: 972 AAENGALGSPEREEKVLENGELTPPRREEKALEN-----GELRSPEAGEKVLVNGGLTPP 1026
Query: 80 RAVLRVSYKGSISY-RNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPP-- 136
++ +VS G + + RN R PP G P RAP + P PT P P
Sbjct: 1027 KSEDKVSENGGLRFPRNTER--PPETG-----PWRAPGPWEKTPESWGPAPTIGEPAPET 1079
Query: 137 -----PAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAP---- 187
PAP A + A P G +PG +RA P AP A
Sbjct: 1080 SLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTE-RRAPETGGAPRAPGAGRLDL 1138
Query: 188 ---------PAVAPPAGP--------------RRAPPPAVAAREPPLPPPPQPPAPPQQQ 224
AP GP R PPP PPLPPPP+ A P++
Sbjct: 1139 GSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPP------PPLPPPPE--AQPRRL 1190
Query: 225 QPPPP--QPQPPPEG--GA--VRAGGAARPVSLREVVRYLGGSGG------AGGRLTR-- 270
+P PP +P+ PEG GA RAGG L G G G + R
Sbjct: 1191 EPAPPRARPEVAPEGEPGAPDSRAGGDTA----------LSGDGDPPKPERKGPEMPRLF 1240
Query: 271 ---GRVQGLLEEEAAARGRLERTRLGALALPRGDRPG-RAPP-----AASARPSRSKRGG 321
G QG E+ A RL L L L PG R PP A +A G
Sbjct: 1241 LDLGPPQGNSEQIKARLSRLS-LALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGA 1299
Query: 322 EERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEW- 380
E E+ED+DE+EDEE + P A A + A ++
Sbjct: 1300 PGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLL 1359
Query: 381 -TPCGPHQGQD------EGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPS--PVPL 431
+P G + +D G T +F E + G PS P P
Sbjct: 1360 KSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPPAPP 1419
Query: 432 PPGKPALPGADGTP 445
P PA PG DG P
Sbjct: 1420 TPPHPATPG-DGFP 1432
Score = 43.5 bits (101), Expect = 5e-04
Identities = 73/299 (24%), Positives = 100/299 (33%), Gaps = 75/299 (25%)
Query: 187 PPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAA 246
PPA P A + + + PP PPPP PP + P P P PP A A
Sbjct: 423 PPAQRPSASDLQLQLTYLLSERPPRPPPP----PPPPRDGPFPWPWPP-------AHSAP 471
Query: 247 RPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARG-----RLERTRLGALALPRGD 301
RP +L L G GA +L ++RG E+ R GA RG
Sbjct: 472 RPGTLSSPFPLLDGFPGAD-------PDDVLTVTESSRGLNLECLWEKARRGA---GRGG 521
Query: 302 -----RPGRAPPAASARPS------------------RSKRGGEERVLEKEEEEDDDED- 337
+P APPA A PS RS E + EE E
Sbjct: 522 GAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPL 581
Query: 338 -EDEEDDVSEGSEVPESDRPAGAQHHQLNGE---------------RGPQSAKERVKEWT 381
++ D + G P++ + A ++ QL E + S + W
Sbjct: 582 FPNDWDPLDPGVPAPQAPQ-APSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWD 640
Query: 382 PCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKE--------GGTASVATGPDSPSPVPLP 432
P G G+ PA G R +E ++S+ GP P+P P
Sbjct: 641 PEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCP 699
Score = 41.2 bits (95), Expect = 0.002
Identities = 113/454 (24%), Positives = 137/454 (30%), Gaps = 104/454 (22%)
Query: 100 QPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP 159
+PPR PP P P P A +A P P P P+ P P +
Sbjct: 444 RPPRPPPPPPPPRDGPFPWPWPPAHSA--PRPGTLSSPFPLLDGFPGADPDDVLTVTESS 501
Query: 160 PSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPP-------------PAVAA 206
+A+R A APA PA APPA P P P ++A
Sbjct: 502 RGLNLECLWEKARRGAGRGG--GAPAWQPASAPPA-PHANPSNPFYEALSTPSVLPVISA 558
Query: 207 REPPLP-----------PPPQPPAP------------PQQQQPPPPQPQPPPEGGAVRAG 243
R P + PP+P P PQ Q P PQ E A
Sbjct: 559 RSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLF 618
Query: 244 GAARPVSLREVVR---YLGG----SGGAGGRLT---------RGRVQGLLEEEAAARGRL 287
A RP + L G GAG L RG + EEE G
Sbjct: 619 PAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSS 678
Query: 288 E----------RTRLGALALPRGDRPGRAPPAASAR-PSRSKRGGEERVLEKEEEEDDDE 336
+R G L P R G R + + GG + EDD
Sbjct: 679 PGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSS 738
Query: 337 DEDEEDDVSEGSEVPESDRP-------AGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQ 389
E +++ P + P GA Q G RGP A P P
Sbjct: 739 LRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPG-RGPPPAPPP----PPPPPRAPA 793
Query: 390 DEGRGP-------APGSG--------------TRQVFSMAAMNKEGGTASVATGPDSPSP 428
D P +PGSG T FS GG A G P
Sbjct: 794 DPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAE-EEGVPRPRA 852
Query: 429 VPLPPGKPALPGADGTPFGCP-PGRKEKPSDPVE 461
P PP P P P P PG +EKP+ V+
Sbjct: 853 PPEPP-DPGAPRPPPDPGPLPLPGPREKPTFVVQ 885
Score = 35.4 bits (80), Expect = 0.13
Identities = 37/140 (26%), Positives = 48/140 (34%), Gaps = 20/140 (14%)
Query: 61 RHGPEPERTRAELE-KLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAP 119
R EPE + E + K++ + V + N VQ P G T P+ P
Sbjct: 1363 RGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTP------- 1415
Query: 120 AAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAA 179
P P PP PA P+ + A P PGP + +
Sbjct: 1416 ---------PAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVS 1466
Query: 180 PPPAPAAPPAVAP---PAGP 196
P PPA AP PAGP
Sbjct: 1467 PALETPGPPARAPDARPAGP 1486
Score = 30.4 bits (67), Expect = 4.3
Identities = 21/65 (32%), Positives = 24/65 (36%), Gaps = 12/65 (18%)
Query: 181 PPAPAAPPAVAPPAGPRRAPPPAVA-----AREPPLPPPPQPP-------APPQQQQPPP 228
PPAP PP A P + A + PL PPP PP P + P P
Sbjct: 1415 PPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVSPALETPGP 1474
Query: 229 PQPQP 233
P P
Sbjct: 1475 PARAP 1479
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 85.5 bits (210), Expect = 1e-16
Identities = 63/169 (37%), Positives = 74/169 (43%), Gaps = 36/169 (21%)
Query: 97 ARVQPPRRGATPPAPPRAPRGAPAAAAAA--APPPTPAPPPPPA-----PVAAAAPARAP 149
A PP +G P+PP +P P A A PP APP PPA P+A +P +AP
Sbjct: 597 ALASPPLQGL--PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP-QAP 653
Query: 150 RAAA-----AAATAPPSP-------GPAQP-----------GPRAQRAAPLAAPPPAPAA 186
A A A + PPSP PA P P + A PL PP PA+
Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713
Query: 187 PPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPP 235
PP P +APPP A PPL PP PPA P P P+ PP
Sbjct: 714 PPMSPSATPPPQAPPPLAA---PPLQVPPSPPASPPMSPSATPPPRVPP 759
Score = 85.1 bits (209), Expect = 1e-16
Identities = 82/256 (32%), Positives = 101/256 (39%), Gaps = 37/256 (14%)
Query: 1 MAGPP--ALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMV 58
+A PP LP P + AT A A P Q + S A P L +
Sbjct: 598 LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQ--------APPSPPASPPLSPLAT-- 647
Query: 59 RRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGA 118
P P+ A L+Q + S A PP A+PP P A +
Sbjct: 648 -----PSPQAPNALAVHLLQ------APFSPPPSPPVQAPFSPP---ASPPVSPSATPPS 693
Query: 119 PAAAAAAAPP----PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRA 174
A + AAPP P+P PP +P A P P AA PPSP PA P P + A
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP-PASP-PMSPSA 751
Query: 175 APLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPP 234
P PP AAPP PP+ P P +A +PP PP PP Q P PP P
Sbjct: 752 TPPPRVPPLLAAPPLQVPPSPPASLPMSPLA--KPPPQAPPALATPPLQALPSPPASFP- 808
Query: 235 PEGGAVRAGGAARPVS 250
G A + A+ P+S
Sbjct: 809 --GQAPFSPSASLPMS 822
Score = 84.3 bits (207), Expect = 2e-16
Identities = 60/159 (37%), Positives = 70/159 (44%), Gaps = 26/159 (16%)
Query: 101 PPRRGATPPAPPRAPRGAP---AAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAAT 157
PP TPP + P A A A+PP P PP +P+A P P A
Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQ 631
Query: 158 APPSPGP-------AQPGPRAQRA-------APLAAPP----PAPAAPPA---VAPPAGP 196
APPSP A P P+A A AP + PP AP +PPA V+P A P
Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 691
Query: 197 RRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPP 235
PP++AA PPL PP PPA P P PQ PP
Sbjct: 692 PSQAPPSLAA--PPLQVPPSPPASPPMSPSATPPPQAPP 728
Score = 78.2 bits (191), Expect = 2e-14
Identities = 51/142 (35%), Positives = 60/142 (42%), Gaps = 18/142 (12%)
Query: 107 TPPAPPRAPRGAPAAAAAAAPPPTP---APPPPPAPVAAAAPARAPRAAAAAATAPPSPG 163
TPP P P AP + PP TP A PPP AP A A+P P + P
Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP---PLQGLPSPPLSPLAT 616
Query: 164 PAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAR--EPPLPPPPQPP--- 218
P P PL APP PA+PP ++P A P P A+A + P PPP PP
Sbjct: 617 PPPQAPPXLALPPLQAPPSPPASPP-LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 675
Query: 219 ------APPQQQQPPPPQPQPP 234
+PP PP PP
Sbjct: 676 PFSPPASPPVSPSATPPSQAPP 697
Score = 77.4 bits (189), Expect = 3e-14
Identities = 58/159 (36%), Positives = 64/159 (40%), Gaps = 28/159 (17%)
Query: 101 PPRRGATPPA------PPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAA 154
PP A+PP PP+AP P AA PP+P PP +P A P P AA
Sbjct: 707 PPSPPASPPMSPSATPPPQAP--PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764
Query: 155 AATAPPSPGPAQP----------GPRAQRAAPLAAPPPAPAAPPAVAP-------PAGPR 197
PPSP + P P A PL A P PA+ P AP P P
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
Query: 198 RAPPPAV--AAREPPLPPPPQPPAPPQQQQP-PPPQPQP 233
PPP P L PP PPA P Q P PP P P
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863
Score = 75.1 bits (183), Expect = 2e-13
Identities = 70/191 (36%), Positives = 80/191 (41%), Gaps = 33/191 (17%)
Query: 101 PPRRGATPPAPPRA---PRGAPAAAAAAAPPPTPAPPPPPA-----PVAAAAPARAPRAA 152
PP A+PP P A PR P AA PP PP PPA P+A P P A
Sbjct: 738 PPSPPASPPMSPSATPPPRVPPLLAA----PPLQVPPSPPASLPMSPLAKPPPQAPPALA 793
Query: 153 AAAATAPPSPGPAQPG-----PRAQ-RAAPLAAPPP-AP---AAPPAVAPPAGPRRAPPP 202
A PSP + PG P A +PLA PPP AP AAP PP+ P A P
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP--ASPT 851
Query: 203 AVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPE-------GGAVRAGGAARPVSLREVV 255
A R PP P P + P+ P P PPP G AG ++ S E +
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 911
Query: 256 RYL--GGSGGA 264
R G GGA
Sbjct: 912 RGYDSGPEGGA 922
Score = 70.1 bits (170), Expect = 5e-12
Identities = 104/391 (26%), Positives = 126/391 (32%), Gaps = 68/391 (17%)
Query: 103 RRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP 162
R A A R P PP +P PPPP P A R AA
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAAL-------RVLGAA------- 50
Query: 163 GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQ---PPA 219
G P A+RA + A P AP AGP R+ ++R P PP A
Sbjct: 51 GAVGRKPLAERAGGIGG-----ATIPESAPRAGPTRS--AGTSSRNPASRPPASGRGERA 103
Query: 220 PPQQQQPPPPQPQPPPEGGAVRAGGAARP---VSLREVV---------RYLGGSGGAGGR 267
PP + P P P G R G + +S E V + S GA R
Sbjct: 104 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA-RR 162
Query: 268 LTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLE 327
T G G A R R T +G LPR PA SARP G + V
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVG---LPR--------PAPSARPRPPTEGPRKSVSS 211
Query: 328 KEEEEDDDEDEDEEDDVSEGS--------EVPESDRPAGAQHHQLNGERGPQSAKERVKE 379
E + S G + S P + RG A +
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271
Query: 380 WTPCG-----PHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPD---SPSPVPL 431
P G P Q + AP G +A + G A PD +P P L
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATL 331
Query: 432 PPGKP---ALPGADGTPFGCPPGRKEKPSDP 459
PP P LP A +P PP + PS P
Sbjct: 332 PPSPPLATPLPLAPPSP-SAPPSLQTLPSPP 361
Score = 68.2 bits (165), Expect = 2e-11
Identities = 56/163 (34%), Positives = 63/163 (38%), Gaps = 16/163 (9%)
Query: 79 QRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPA 138
QR R + + AR P RG TP AP + P A PP P
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARG-TPRAPAHPSQPKPKGLQALRPPQVTPPRKD-- 291
Query: 139 PVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAA---PLAAPPPAPAAPPAVAPPAG 195
AAPA P +++ AT PS A+P P AA P PP P A P P
Sbjct: 292 ----AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS 347
Query: 196 PRRAPPPAVAAREPPLPPPPQPPAPPQQQQPP---PPQPQPPP 235
P APP PP PP Q APP PP PP Q P
Sbjct: 348 PS-APPSLQTLPSPPATPPSQ--APPSMTTPPMQAPPSLQTIP 387
Score = 63.2 bits (152), Expect = 6e-10
Identities = 47/133 (35%), Positives = 54/133 (40%), Gaps = 13/133 (9%)
Query: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAP-ARAPRAAAAAATAPPSPGP 164
ATP + P R P+A P P+ P P A P PR AA A P S P
Sbjct: 246 ATPLSSPA--RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 165 -AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQ 223
A P P +A P+ P A PA PP+ P P P L PP P APP
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP--------LAPPS-PSAPPSL 354
Query: 224 QQPPPPQPQPPPE 236
Q P P PP +
Sbjct: 355 QTLPSPPATPPSQ 367
Score = 62.8 bits (151), Expect = 8e-10
Identities = 47/140 (33%), Positives = 55/140 (39%), Gaps = 13/140 (9%)
Query: 99 VQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATA 158
+ PP + APP + PA+ P+ PPP A+A P P
Sbjct: 508 IMPPLETQSSLAPPSL-QTPPASLTTPPLENLPSLAPPPLQTASA-PLTTPHLET----- 560
Query: 159 PPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPP-AGPRRAPPPAVAAREPPLPP--PP 215
PP P P P +PL PPP + A PP A P A PP PPL P P
Sbjct: 561 PPCPAPC---PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP 617
Query: 216 QPPAPPQQQQPPPPQPQPPP 235
P APP PP P PP
Sbjct: 618 PPQAPPXLALPPLQAPPSPP 637
Score = 61.2 bits (147), Expect = 2e-09
Identities = 85/304 (27%), Positives = 100/304 (32%), Gaps = 113/304 (37%)
Query: 100 QPPRRGATPP-----APPRA-PRGAPAAAAAAAP-PPTPAPPPPPAPVAAAAPARAPRAA 152
Q P ATPP +PP + P AP + +A+ P P PPP PV AA + P +
Sbjct: 787 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846
Query: 153 AAAAT-----APPSPGP--AQPGPRAQRAAPLAAPPP----------------------- 182
A+ T PP+PGP + GPR A PPP
Sbjct: 847 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 906
Query: 183 ---------------APAAPP-----AVAPPAGPRRAPPPAVAAREPPLPPPPQPPAP-- 220
A A+PP A PA R P P +A R P P P PPA
Sbjct: 907 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP 966
Query: 221 --------------PQQQQPPP----PQPQPPPEGGAVRAGGAA-----RPVSLR----- 252
P+ P P P P P GG AG A P R
Sbjct: 967 GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 1026
Query: 253 ------EVVRYL--------------GGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRL 292
VV++L GGSGG G G V G AR L L
Sbjct: 1027 LGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTG------GARAALSDAEL 1080
Query: 293 GALA 296
G A
Sbjct: 1081 GRWA 1084
Score = 60.8 bits (146), Expect = 3e-09
Identities = 49/147 (33%), Positives = 62/147 (42%), Gaps = 35/147 (23%)
Query: 98 RVQPPRRGATPPAPP--RAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA 155
+V PPR+ A P P +P P+ + A P PPP A A
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKA---RPVPPPDNA------------ATPLP 328
Query: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAV----APPAGPRRAPPPAVAAREPPL 211
AT PPSP A P P A PP+P+APP++ +PPA P PP++ PP+
Sbjct: 329 ATLPPSPPLATPLPLA---------PPSPSAPPSLQTLPSPPATPPSQAPPSMTT--PPM 377
Query: 212 PPPPQPPAPPQQQQP---PPPQPQPPP 235
PP P Q P P Q PP
Sbjct: 378 QAPPSLQTIPPIQVPHSLTSPSLQAPP 404
Score = 57.4 bits (137), Expect = 3e-08
Identities = 51/148 (34%), Positives = 59/148 (39%), Gaps = 25/148 (16%)
Query: 107 TPPAPPRAPRGAPAAAAAAAPPPTPAPPPPP--APVAAAAPARAP---RAAAAAATAPPS 161
+P AP + P ++ PP+ PP P P+ AP + A+A T P
Sbjct: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL 558
Query: 162 PGPAQPGPRAQRAAPLAAPP-PAPAAPP------AVAPP-AGPRRAPPPAVAAREPPL-- 211
P P P PL APP P PP A PP A P A PP PPL
Sbjct: 559 ETPPCPAP-----CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP 613
Query: 212 ---PPPPQPP--APPQQQQPPPPQPQPP 234
PPP PP A P Q PP P PP
Sbjct: 614 LATPPPQAPPXLALPPLQAPPSPPASPP 641
Score = 55.5 bits (132), Expect = 1e-07
Identities = 53/152 (34%), Positives = 69/152 (45%), Gaps = 19/152 (12%)
Query: 96 AARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPT---PAPPPPPAPVAAAAPARAPRAA 152
A+ P R +TPP P P AP + A+ P T PA P +P+ P +A +
Sbjct: 439 ASLTSPSRPASTPPDSP--PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH-PLQA--LS 493
Query: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPA--VAPPAG--PRRAPPPAVAARE 208
+ A+ +P +P + P + + LA PP+ PPA PP P APPP A
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLA--PPSLQTPPASLTTPPLENLPSLAPPPLQTASA 551
Query: 209 P----PLPPPPQPPAPPQQQQPPPPQPQPPPE 236
P L PP PAP Q PP P PPPE
Sbjct: 552 PLTTPHLETPP-CPAPCPLQAPPSPLTTPPPE 582
Score = 48.5 bits (114), Expect = 2e-05
Identities = 73/300 (24%), Positives = 95/300 (31%), Gaps = 112/300 (37%)
Query: 4 PPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHG 63
PP + PP AA +SS A+P S KARP
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATP-----------SPSGTKARP-------------V 317
Query: 64 PEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAA 123
P P+ L + PP P APP +P P+
Sbjct: 318 PPPDNAATPLPATLPP--------------------SPPLATPLPLAPP-SPSAPPSLQT 356
Query: 124 AAAPPPTP---APP----PP---PAPVAAAAPARAPRA-AAAAATAPPSP---------- 162
+PP TP APP PP P + P + P + + + APPSP
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416
Query: 163 --------------------------GPAQPGPRAQRAAPLAAPPPAPAAP-------PA 189
P++P + PL AP PA+P PA
Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA 476
Query: 190 VAPPAGPRRAPP----PAVAAREP--PLPPPPQPP-------APPQQQQPPPPQPQPPPE 236
V+P + P P ++A+ P PL PP APP Q PP PP E
Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
Score = 46.2 bits (108), Expect = 8e-05
Identities = 73/268 (27%), Positives = 91/268 (33%), Gaps = 65/268 (24%)
Query: 100 QPPRRGATPPAPPRAPRGAPAAAAAAA------------------PPPTP-APPPPPAPV 140
+PP G+ P PP P AA A P P A P A
Sbjct: 28 RPP--GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85
Query: 141 AAAAPARAPRAAAAAATAPP----SPGP----------AQPGPRAQRAAPLAAPP----- 181
++ PA P A+ APP SPGP +PGP Q+ ++A
Sbjct: 86 SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 145
Query: 182 PAPAAPPAVAPPAGPRR--------APPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQP 233
A AP A AG RR P PA+A R P P P +P+P
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP-----APSARPRP 200
Query: 234 PPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLG 293
P EG ++ +A S E AGG L R + L T L
Sbjct: 201 PTEGPR-KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS---------SATPLS 250
Query: 294 ALALPRGDRPGRAPPAASARPSRSKRGG 321
+ A R R P A A PS+ K G
Sbjct: 251 SPA--RSGPSARGTPRAPAHPSQPKPKG 276
Score = 42.4 bits (98), Expect = 0.001
Identities = 58/232 (25%), Positives = 75/232 (32%), Gaps = 78/232 (33%)
Query: 89 GSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAP--------- 139
G+ +A R P R T P + A A P +P P +P
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
Query: 140 ---------------VAAAAPARAPRAAAAAA-----TAPPSPGPAQPG-PRAQRAA--P 176
VA AP+ +A +A T+ P+PG P R RAA
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 177 LAAPPPAPAAPPAVAPPAGPRRA----------PPPAVAAREP----------------- 209
+ P PAP+A P P GPR++ P A R P
Sbjct: 187 VGLPRPAPSARPR-PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 210 --PLPPP----------PQPPAPPQQQQPP------PPQPQPPPEGGAVRAG 243
PL P P+ PA P Q +P PPQ PP + A G
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 85.5 bits (210), Expect = 1e-16
Identities = 108/401 (26%), Positives = 137/401 (34%), Gaps = 65/401 (16%)
Query: 101 PPRRGA--TPPAPPRAPRGAPAAAAAAAPPPTPA--PPPPPAPVAAAAPARAPRAAAAAA 156
PP +GA TP A P +P+G A P TPA PP P +A +P AP AA
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT- 1201
Query: 157 TAPPSP--GPAQPGPRAQRAAPLAAPPP------------APAAPPAVAP-PAGPRRAPP 201
PPSP G A P P+ P A PP AP P A P P G PP
Sbjct: 1202 --PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259
Query: 202 PAVAAREPPLPPPPQPPA-------PPQQQQPPPPQPQPP-PEGGAVRA---GGAARPVS 250
P A P PP PP+ PP + P P PP P+GG + G P +
Sbjct: 1260 PKGA----PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA 1315
Query: 251 LREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAA 310
+ G+ G T V + + G P + G PPAA
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP-SSKEGPTPPAA 1374
Query: 311 SARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGP 370
+ S +GG + + + D + + +P S + A A G P
Sbjct: 1375 TP----SHKGGP--AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP 1428
Query: 371 QSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVP 430
TP + AP G A + +G A P SP P
Sbjct: 1429 SKGDLTPPAVTPVSLKKAPATS---APKGGP------ATPSSKGDPTLPAVTPPSPKEPP 1479
Query: 431 LP------------PGKPALPGADGTPFGCPPGRKEKPSDP 459
P P PA GA P P KE P+ P
Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP 1520
Score = 82.8 bits (203), Expect = 7e-16
Identities = 106/385 (27%), Positives = 140/385 (36%), Gaps = 64/385 (16%)
Query: 101 PPRRGA--TPPAPPRAPRGAPAAAAAAAPPPTPA--PPPPPAPVAAAAPARAPRAAAAAA 156
PP +GA TP A P +P+G A + P TPA PP P +A +P AP AA
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT- 1224
Query: 157 TAPPSP--GPAQPGPRAQRAAPLAAPP--------PAPAA---PPAVAPPA--GPRRAPP 201
PPSP G A P P+ P A PP P P PPA PP+ G PP
Sbjct: 1225 --PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282
Query: 202 ----PAVAAREPPLP-------PPPQPPAPPQQQQPPPP-QPQPPPEGGAVRAGGAARPV 249
P A PP P PP P PP P P P PP GA P
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342
Query: 250 SLREVVRYLGGSGGAGGRLTRGRVQGLLEEEA--AARGRLERT-----RLGALALPRGDR 302
GG T +G A + +G T R A+ P+GD
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD- 1401
Query: 303 PGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHH 362
P + + P K+ V + + D++ + P S + A A
Sbjct: 1402 ----PTSPAVIPLSPKKAPATPVTR------EGAATPSKGDLTPPAVTPVSLKKAPATSA 1451
Query: 363 QLNGERGPQSAKE-RVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVAT 421
G P S + + TP P + PAP +QV + ++ K T +
Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPPSPKE------PPAP----KQVATSSSPKKAPATPAPMG 1501
Query: 422 GPDSPSPVPLPPGK-PALPGADGTP 445
P P+ +P P + PA P + P
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDP 1526
Score = 81.6 bits (200), Expect = 2e-15
Identities = 108/396 (27%), Positives = 127/396 (32%), Gaps = 74/396 (18%)
Query: 101 PPRRGA--TPPAPPRAPRGAPAAAAAAAPPPTPA--PPPPPAPVAAAAPARAPRAAAAAA 156
PP +GA TP A P +P+G A P TPA PP P +A P AP AA
Sbjct: 1120 PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT- 1178
Query: 157 TAPPSP--GPAQPGPRAQRAAPLAAPPP------------APAAPPAVAP-PAGPRRAPP 201
PPSP G A P P+ P A PP AP P A P P G P
Sbjct: 1179 --PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236
Query: 202 PAVAAREPPLPPPPQ---PPAPPQQQQPPPPQPQPPPEGGAVRA---GGAARPVSLREVV 255
P A P PP P PP + P PP PP G + GA P VV
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA----VV 1292
Query: 256 RYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRG--DRPGRAPPAASAR 313
GG +G + +G P+G P PP+
Sbjct: 1293 TPPSPKGGPATSPPKGAPTPPAATPPSPKGS------PGTPPPKGAPTPPAVTPPSPKGT 1346
Query: 314 P-----SRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGER 368
P + S +GG KE PA H+
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTP----------------------PAATPSHKGGPAM 1384
Query: 369 GPQSAKERVKEWTPCG-PHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPS 427
P S K +P G P P T AA +G A P S
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK 1444
Query: 428 PVP---LPPGKPALPGADG---TPFGCPPGRKEKPS 457
P P G PA P + G P PP KE P+
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPA 1480
Score = 80.1 bits (196), Expect = 5e-15
Identities = 107/405 (26%), Positives = 131/405 (32%), Gaps = 60/405 (14%)
Query: 102 PRRGATPPAP-PRAPRGAPAAAAA--AAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATA 158
P+ TPPA P +P+G PA + A PP PP P A +P AP AA
Sbjct: 936 PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAA---T 992
Query: 159 PPSP--GPAQPGPRAQRAAPLAAPPP---APAA---------PPAVAPPA---GPRRAPP 201
PPSP GPA P P+ P PP +PAA PPA PP+ P P
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052
Query: 202 PAVAAREP-------------------PLPPPPQPPAPPQQQQPPPPQ--PQPPPEGGAV 240
P A P P PP PP+P P P+ P PP
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
Query: 241 RAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRG 300
GG A P G L +G AA + G LA P
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT----PPSPKGGLATP-- 1166
Query: 301 DRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQ 360
P AP +A P K G + + ++ S PA
Sbjct: 1167 -PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225
Query: 361 HHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVA 420
G P + TP G P G + + +GG A+
Sbjct: 1226 PSPKGGLATP---SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282
Query: 421 -TGPDSPSPV--PLPPGKPAL---PGADGTPFGCPPGRKEKPSDP 459
G +P+ V P P G PA GA P PP K P P
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Score = 76.3 bits (186), Expect = 7e-14
Identities = 55/157 (35%), Positives = 65/157 (41%), Gaps = 19/157 (12%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAA--AAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATA 158
P + ATP AP+G PA+ + A PP PP P A +P AP AA
Sbjct: 918 PKKARATP-----APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT--- 969
Query: 159 PPSP--GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQ 216
PPSP GPA P P+ P AA PP+P PA P G AP P P P
Sbjct: 970 PPSPKGGPATPSPKGAPTPP-AATPPSPKGGPATPSPKG---APTPPAVTPPSPKGSPAA 1025
Query: 217 PPAPPQQQQPP---PPQPQPPPEGGAVRAGGAARPVS 250
P P PP PP P+ P + G P +
Sbjct: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA 1062
Score = 75.9 bits (185), Expect = 9e-14
Identities = 60/179 (33%), Positives = 67/179 (37%), Gaps = 32/179 (17%)
Query: 102 PRRGATPPAPPRAP------------RGAPAAAAA-AAPPPTPAPPP----PPAPVAAAA 144
P+ G PAP +AP R PA A+P P AP P PP+P A
Sbjct: 896 PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPA 955
Query: 145 PARAPRAAAAAATAPPSP--GPAQPGPRAQRAAPLAAPP--------PAP---AAPPAVA 191
A A PPSP GPA P P+ P A PP P+P PPAV
Sbjct: 956 TPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015
Query: 192 PPA--GPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARP 248
PP+ G A P A PP PP P P P P P GG A P
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074
Score = 73.9 bits (180), Expect = 3e-13
Identities = 105/415 (25%), Positives = 131/415 (31%), Gaps = 76/415 (18%)
Query: 86 SYKGSISYRNAARVQPPRRGATPPAPPRAP-----RGAPAAAAAAAP-----PPTPAPPP 135
S KGS + + P AT P+P P +GAP AA P P TP+P
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101
Query: 136 PPAPVAAAAPA-RAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPP--APAAPPAVAP 192
P P AA P+ + A AP +P P P+ LA PPP AP P A P
Sbjct: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK----GGLATPPPKGAPTTPAATPP 1157
Query: 193 -PAGPRRAPPPAVAAREPPLPPP--------PQPPAPPQQQQPPPPQPQ-----PPPEGG 238
P G PPP A P PP P P P PP P+ P P+G
Sbjct: 1158 SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1217
Query: 239 AVR--------AGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERT 290
GG A P G +G AA L+
Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK-- 1275
Query: 291 RLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEV 350
G LA P P + P + S +GG K G+
Sbjct: 1276 --GGLATP----PHKGAPNPAVVTPPSPKGGPATSPPK------------------GAPT 1311
Query: 351 PESDRPAGAQHH----QLNGERGPQSAKERVKEWTPCGPHQGQDEGRGP-APGSGTRQVF 405
P + P + G P + + TP P GP P S
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
Query: 406 SMAAMNKEGGTASVATGPDSPSPVPLPPGKPALPGADGTPFGCPPGRKEKPSDPV 460
A + +GG A P +P P G P P P K+ P+ PV
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV------IPLSPKKAPATPV 1420
Score = 67.8 bits (164), Expect = 2e-11
Identities = 59/192 (30%), Positives = 76/192 (39%), Gaps = 41/192 (21%)
Query: 88 KGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAP-----PPTPAPPP------- 135
+ S+S++ + TPP+P AP P+A +P PP P P
Sbjct: 838 ENSLSFQGSKDSPATTHSPTPPSPKGAP--TPSAVTPLSPKGVTLPPKETPTPSVVNLPF 895
Query: 136 ----PPAPVAAAAPARAPRAAA---AAATAPPSPGPAQPGPRAQRAAPLAAPP------- 181
P P APA + +++ A AT P PA P P+ P A PP
Sbjct: 896 PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPA 955
Query: 182 -PAP---AAPPAVAPPA---GPRRAPPPAVAAREPPLPPPPQP---PAPPQQQ-QPPPPQ 230
P+P PPA PP+ GP A P A PP PP P PA P + P PP
Sbjct: 956 TPSPKWAPTPPAATPPSPKGGP--ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 231 PQPPPEGGAVRA 242
PP G+ A
Sbjct: 1014 VTPPSPKGSPAA 1025
Score = 62.8 bits (151), Expect = 8e-10
Identities = 127/533 (23%), Positives = 184/533 (34%), Gaps = 106/533 (19%)
Query: 4 PPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHG 63
PPA+ PP T A SS P T S + P +
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGP--------TTPSSKEGPTPPAATPSHKGGPAMTP 1386
Query: 64 PEPERTRA--ELEKLIQQRAVLRVSYKGS----ISYRNAARVQPPRRGATPPA------- 110
P P+R A + AV+ +S K + ++ AA P + TPPA
Sbjct: 1387 PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT--PSKGDLTPPAVTPVSLK 1444
Query: 111 ---PPRAPRGAPAAAAA-------AAPPPTPAPPPPPAPVA-AAAPARAPRAAA--AAAT 157
AP+G PA ++ A PP+P PP P VA +++P +AP A A T
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT 1504
Query: 158 AP------PSPGPAQPGPRAQRAAP----LAAPPPAPAAP-PAVAPPA----GPRRAP-- 200
P P PA P R AP L+ PA AP A+ PPA P++ P
Sbjct: 1505 LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAI 1564
Query: 201 ------PPAVAAREPPLPP------------------PPQPPAPPQQQQPPPPQPQPP-P 235
P +++E PP PP +P ++ P PP PP P
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624
Query: 236 EGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGAL 295
E G P S L S + +T + + + T L +
Sbjct: 1625 EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684
Query: 296 ALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESD- 354
+ AP + + +++G + + + + GS+ P S
Sbjct: 1685 LV------APAPESTPIITAPTRKGPQTK-----KSSATSPPICPDPSAKNGSKGPLSTV 1733
Query: 355 RPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEG 414
PA Q + + +AK + +P GP E + P T F E
Sbjct: 1734 APAPLLPVQKDSSK---TAKGKDASHSPKGP-LAPPESKASTP--LTAAAFEKVLPKPES 1787
Query: 415 GTASVATGPD-----SPSPVP-LPPGKPALPGADGTPFGCPPGRKEKPSDPVE 461
+ S A P +PSPVP LPP + LP + G P KP P +
Sbjct: 1788 ASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESP----SKPLAPAD 1836
Score = 51.6 bits (122), Expect = 2e-06
Identities = 46/177 (25%), Positives = 57/177 (32%), Gaps = 34/177 (19%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAA--------------PPPTPAPPPPPAPVAAAAPA 146
P ++G+ P P +P + A+ P T P PP+P A P+
Sbjct: 809 PTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPS 868
Query: 147 RAPRAAAAAATAPPSPGPAQ-----PGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPP 201
+ T PP P P P+ A P AP APA + P R P
Sbjct: 869 AVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP--APKQAPALSMTSSSPKKARATPA 926
Query: 202 PAVAAREPPLPPPPQPPAPPQQQQPPPP----------QPQPPPEGGAVRAGGAARP 248
P P P P P PP P P P PP GG A P
Sbjct: 927 PKGI---PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP 980
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/154 (27%), Positives = 55/154 (35%), Gaps = 22/154 (14%)
Query: 115 PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQ-------- 166
P + + AA P P PPP +P AP + P +AA A+ PSP
Sbjct: 27 PMSSALSVTAALGQPGPTLPPPCSP----APQQCPLSAANQASPFPSPSTIASTPLEVPF 82
Query: 167 PGPRAQRAAPLAAPPPAPA-APPAVAPP--------AGPRRAPP-PAVAAREPPLPPPPQ 216
P + A PL P AP P + PP A P AP + PL
Sbjct: 83 PQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVAL 142
Query: 217 PPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVS 250
P Q+ PP P AV G+ +S
Sbjct: 143 APHSVQKSSAFPPNLLTSPPSVAVAESGSVITLS 176
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/195 (26%), Positives = 72/195 (36%), Gaps = 31/195 (15%)
Query: 69 TRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPP 128
T EL + + AVL +S S++ A + P PP P AP+ P +AA A P
Sbjct: 12 TEQELPQPQAETAVLPMSSALSVT----AALGQPGPTLPPPCSP-APQQCPLSAANQASP 66
Query: 129 PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP-------GPAQPGPRAQRAAPLAAP- 180
P+ P + A TAP +P GP A+P+ AP
Sbjct: 67 FPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPT 126
Query: 181 ------PPAPAAPPAVAPPAGPRRA--------PPPAVAAREP----PLPPPPQPPAPPQ 222
AP A A+AP + + + PP+VA E L P P P
Sbjct: 127 LKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKT 186
Query: 223 QQQPPPPQPQPPPEG 237
P + P P+G
Sbjct: 187 NLNKVPSEVVPNPKG 201
Score = 36.2 bits (82), Expect = 0.078
Identities = 38/156 (24%), Positives = 60/156 (38%), Gaps = 19/156 (12%)
Query: 98 RVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPV----AAAAPARAPRAAA 153
R P + ++ +PP P P+A + P + P P PV + A + +
Sbjct: 1701 RKGPQTKKSSATSPPICPD--PSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSP 1758
Query: 154 AAATAPPSPGPAQPG---------PRAQRAAPLAAPPPAPAAP--PAVAPPAGPRRAPPP 202
APP + P P+ + A+ AAP P + P P+ P P++ P
Sbjct: 1759 KGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLP 1818
Query: 203 AVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGG 238
+ L P +P AP + + P P P GG
Sbjct: 1819 SSPGL--VLESPSKPLAPADEDELLPLIPPEPISGG 1852
Score = 36.2 bits (82), Expect = 0.078
Identities = 31/121 (25%), Positives = 40/121 (33%), Gaps = 3/121 (2%)
Query: 108 PPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPG--PA 165
P APP + P AAA P P A + P P A + T PP P+
Sbjct: 1761 PLAPPESKASTPLTAAAFEK-VLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPS 1819
Query: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQ 225
PG + + AP P + P P +V P P P +Q
Sbjct: 1820 SPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQ 1879
Query: 226 P 226
P
Sbjct: 1880 P 1880
Score = 34.7 bits (78), Expect = 0.23
Identities = 84/379 (22%), Positives = 119/379 (31%), Gaps = 70/379 (18%)
Query: 119 PAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP----------SPGPAQPG 168
P ++ P A P A A AP A + TA P P + G
Sbjct: 634 PLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEG 693
Query: 169 --------PRAQRAAPLAAPPPAPAAPPA--VAPPAGPRRAPPPAVAAREPPLPPPPQPP 218
P A P+A P AP A V P P+ P P+ LPP PP
Sbjct: 694 TLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPS-------LPPAGTPP 746
Query: 219 APPQQQQPPPPQPQPP----PEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQ 274
+ P P+ GA+ S + + YL S G + +
Sbjct: 747 GTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTK 806
Query: 275 GLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDD 334
++ +A T +G L+ P +P AS P S L + +D
Sbjct: 807 RPPTKKGSAG---PDTPIGNLSSPV------SPVEASFLPENS--------LSFQGSKDS 849
Query: 335 DEDEDEEDDVS-EGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGR 393
S +G+ P + P + L + P + + P +G
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPF-----PKEGPAT-- 902
Query: 394 GPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSP----------VPLPPGKPALPG--- 440
PAP + ++ K T + P SPSP P P G PA P
Sbjct: 903 -PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW 961
Query: 441 ADGTPFGCPPGRKEKPSDP 459
A P PP K P+ P
Sbjct: 962 APTPPAATPPSPKGGPATP 980
Score = 33.9 bits (76), Expect = 0.39
Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 10/125 (8%)
Query: 123 AAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA-----ATAPP--SPGPAQ-PGPRAQRA 174
A P T P P A P + + AA T PP SP P Q P A +A
Sbjct: 5 ATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQA 64
Query: 175 APLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPP--LPPPPQPPAPPQQQQPPPPQPQ 232
+P +P + P V P P A E P LP PP P P
Sbjct: 65 SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIA 124
Query: 233 PPPEG 237
P +G
Sbjct: 125 PTLKG 129
Score = 33.5 bits (75), Expect = 0.50
Identities = 39/171 (22%), Positives = 58/171 (33%), Gaps = 14/171 (8%)
Query: 90 SISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAA--AAPAR 147
S+ + + P +R PP P R A AA P P+ P+ +++ +P+
Sbjct: 340 SVDHSSTGASYPSQRSVIPPLPSR--NEVVPATVAAFPVVAPSVDKGPSTISSITCSPSG 397
Query: 148 APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPA---APPAVAPPAGPRRAPPPAV 204
+ A + + +P + + P A PL A P + P V P A P
Sbjct: 398 SLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPC--TIAAAPTT 455
Query: 205 AAREPPLPPPPQPPAPPQQQQPPPP-----QPQPPPEGGAVRAGGAARPVS 250
PP P +P P P P E A PVS
Sbjct: 456 TFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVS 506
Score = 32.0 bits (71), Expect = 1.5
Identities = 88/423 (20%), Positives = 120/423 (28%), Gaps = 90/423 (21%)
Query: 102 PRRGATPPA-PPRAPRGAPAAAAAAAP--PPTPAPPPPPAPVAAAAPARAPRAAAAAATA 158
P A P P +G A+P T + P PV P A+
Sbjct: 649 PLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENC 708
Query: 159 PPSPGPAQ---PGPRAQRAAPLAAPPPAPAAPPAVAPP------------------AGPR 197
P +P P P A + P+P+ PPA PP + P+
Sbjct: 709 PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPK 768
Query: 198 RAP-----PPAVAAREPPLPPPPQPPAP------PQQQQPPPPQPQPPPEGGAVRAGGAA 246
P A A+ + L P+P PQ ++PP + P+ G +
Sbjct: 769 ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD---TPIGNLS 825
Query: 247 RPVSLREV----VRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDR 302
PVS E L G T + A + + LP +
Sbjct: 826 SPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKET 885
Query: 303 P------------GRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEV 350
P G A PA P+ S + + +G +
Sbjct: 886 PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPK-------------KARATPAPKG--I 930
Query: 351 PESDRPAGAQHHQLNGERGPQSAKERVK-EWTPCGPHQGQDEGRGPAPGSGTRQVFSMAA 409
P S P GA P+ +W P P P+P G A
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP-----AATPPSPKGGPATPSPKGA 985
Query: 410 MNKEGGT-ASVATGPDSPSP----------VPLPPGKPAL----PGADGTPFGCPPGRKE 454
T S GP +PSP P P G PA GA P PP K
Sbjct: 986 PTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG 1045
Query: 455 KPS 457
P+
Sbjct: 1046 SPA 1048
Score = 29.6 bits (65), Expect = 7.3
Identities = 36/129 (27%), Positives = 45/129 (34%), Gaps = 33/129 (25%)
Query: 105 GATPPAPPRAPRGAPAAAAAAAPPPTPA----PPPPPAPVAAAAP-ARAPRAAAAAA--- 156
G P AP P PP +PA P AP P + AP A A A
Sbjct: 94 GTAPEAPTFLPN-------LIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHS 146
Query: 157 ------------TAPPSPGPAQPGPRAQRAAPLAAPPPAP---AAPPAVAPPAGPRRAP- 200
T+PPS A+ G +AP+A P P V P P+ P
Sbjct: 147 VQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVP--NPKGTPS 204
Query: 201 PPAVAAREP 209
PP + + P
Sbjct: 205 PPCIVSTVP 213
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 84.0 bits (206), Expect = 3e-16
Identities = 60/144 (41%), Positives = 73/144 (50%), Gaps = 23/144 (15%)
Query: 109 PAPPRAPRGAPAAAA--AAAPPPTPAPPPPPA-----PVAAAAPARAPRAAA-----AAA 156
P+PP +P P A A A PP APP PPA P+A +P +AP A A A
Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP-QAPNALAVHLLQAPF 440
Query: 157 TAPPSP-------GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREP 209
+ PPSP PA P P + A P + PP+ AAPP PP+ P +PP + +A P
Sbjct: 441 SPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPS-PPASPPMSPSATPP 498
Query: 210 PLPPPPQPPAPPQQQQPPPPQPQP 233
P PPP APP Q PPPQ P
Sbjct: 499 PQAPPPL-AAPPLQLAKPPPQAPP 521
Score = 79.0 bits (193), Expect = 1e-14
Identities = 81/278 (29%), Positives = 107/278 (38%), Gaps = 54/278 (19%)
Query: 2 AGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLR----SRKARPDLERICRM 57
+ P A P P +AA + A + A+PH L S A P L+ +
Sbjct: 301 SSPLATPSP---SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL--- 354
Query: 58 VRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPA---PPRA 114
P P T L+ ++ S + PP + PPA PP
Sbjct: 355 ------PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA--PPALALPPLQ 406
Query: 115 PRGAPAAAAAAAPPPTPAP---------------PPPPAPVAAAAPARAPRAAAAAATAP 159
+P A+ +P TP+P PPP+P P +AP + A+
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-----PVQAPFSPPASPPVS 461
Query: 160 PSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPL----PPPP 215
PS P P + A PL PP PA+PP P +APPP A PPL PPP
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA---PPLQLAKPPPQ 518
Query: 216 QPPA---PPQQQQPPPPQPQPPPEGGAVRAGGAARPVS 250
PPA PP Q P PP P G A + A+ P+S
Sbjct: 519 APPALATPPLQALPSPPASFP---GQAPFSPSASLPMS 553
Score = 75.9 bits (185), Expect = 9e-14
Identities = 68/218 (31%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 102 PRRGATPPAPPRAPRGAPAAAAA----AAPPPTP-APPPPPAPVAAAAPA-RAPRAAAAA 155
P ATPP+ G+P A +PP +P A PPP AP A A P +AP + A+
Sbjct: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414
Query: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPP 215
P P+ P A L AP P +PP AP + P A PP + PP PP
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP--ASPPVSPSATPPSQAPP 472
Query: 216 QPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQG 275
APP Q PP P PP A A P++ ++ A L +Q
Sbjct: 473 SLAAPPLQV-PPSPPASPPMSPSATPPPQAPPPLA-APPLQLAKPPPQAPPALATPPLQA 530
Query: 276 LLEEEAAARGRLERTRLGALAL-PRGDRPGRAPPAASA 312
L A+ G+ + +L + P P +APP +A
Sbjct: 531 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
Score = 75.9 bits (185), Expect = 9e-14
Identities = 61/169 (36%), Positives = 70/169 (41%), Gaps = 36/169 (21%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAA--------APPPTPA-------PPPPPAPVAAAAP 145
PP A+PP P A A A A +PPP+P P PP +A P
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467
Query: 146 ARAPRAAAAAAT-APPSPGPAQPG------PRAQRAAPLAAPP-----PAPAAPPAVAPP 193
++AP + AA PPSP PA P P Q PLAAPP P P APPA+
Sbjct: 468 SQAPPSLAAPPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL--- 523
Query: 194 AGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRA 242
A PP A PP P Q P P P P PPP+ V A
Sbjct: 524 -----ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 567
Score = 73.6 bits (179), Expect = 4e-13
Identities = 79/259 (30%), Positives = 101/259 (38%), Gaps = 44/259 (16%)
Query: 1 MAGPPALPPPE--TAAAATTAAAASSSAASPHYQEWI-----------LDTIDSLRSRKA 47
+ PPA PP + T+ + T A S SP L + + S A
Sbjct: 354 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 413
Query: 48 RPDLERICRMVRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGAT 107
P L + P P+ A L+Q + S A PP A+
Sbjct: 414 SPPLSPLAT-------PSPQAPNALAVHLLQ------APFSPPPSPPVQAPFSPP---AS 457
Query: 108 PPAPPRAPRGAPAAAAAAAPP----PTPAPPPPPAPVAAAAPARAPRAAA---AAATAPP 160
PP P A + A + AAPP P+P PP +P A P P AA A PP
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517
Query: 161 SPGPAQPGP--RAQRAAPLAAPPPAPAAPPA---VAPPAGPRRAPPPAVAAREPPLPPPP 215
PA P +A + P + P AP +P A ++P A P PP +AA P L PP
Sbjct: 518 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA--PLLQVPP 575
Query: 216 QPPAPPQQQQP-PPPQPQP 233
PPA P Q P PP P P
Sbjct: 576 SPPASPTLQAPRRPPTPGP 594
Score = 67.8 bits (164), Expect = 2e-11
Identities = 50/165 (30%), Positives = 62/165 (37%), Gaps = 16/165 (9%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAP-------------AR 147
PP A+PP P A A AAPP A PPP AP A A P +
Sbjct: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 541
Query: 148 APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAR 207
AP + +A+ P P P A L PP PA+P AP P P +V+
Sbjct: 542 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 601
Query: 208 EPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLR 252
L P PP PP + P P+ + + P LR
Sbjct: 602 RLTLALAPGPPPPPSRS---PSSTLSGPDLAGHSSSATSTPEELR 643
Score = 66.6 bits (161), Expect = 5e-11
Identities = 57/190 (30%), Positives = 73/190 (38%), Gaps = 54/190 (28%)
Query: 98 RVQPPRRGATPPAPP--RAPRGAPAAAAAA---APPPTPAPP---------PPPAPVAAA 143
+V PPR+ A P P +P P+ +AA APP PA P P P+A
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP 343
Query: 144 APARAP--RAAAAAATAPPSPGPAQPGPRAQRA----------APLAAPPP--------- 182
+P+ P + + PPS G +A +PLA PPP
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403
Query: 183 ---APAAPPAVAPPAGPRRAPPP------AVAAREPPLPPPPQPP---------APPQQQ 224
AP +PPA +PP P P P AV + P PPP PP +PP
Sbjct: 404 PLQAPPSPPA-SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 462
Query: 225 QPPPPQPQPP 234
PP PP
Sbjct: 463 SATPPSQAPP 472
Score = 63.9 bits (154), Expect = 3e-10
Identities = 50/146 (34%), Positives = 58/146 (39%), Gaps = 32/146 (21%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPP---PPAPVAAAAPARAPRAAAAAAT 157
PP A P P +P +P + +A PPP APPP PP +A P P A
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATPPPQ-APPPLAAPPLQLAKPPPQAPPALATPPLQ 529
Query: 158 APPSPGPAQPG-----PRAQRA-APLAAPPP------------APAAPPAVAPPAGPRRA 199
A PSP + PG P A +PLA PPP P +PPA PRR
Sbjct: 530 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 589
Query: 200 PPPA----------VAAREPPLPPPP 215
P P A P PPPP
Sbjct: 590 PTPGPDTSVSGPRLTLALAPGPPPPP 615
Score = 61.2 bits (147), Expect = 2e-09
Identities = 85/304 (27%), Positives = 100/304 (32%), Gaps = 113/304 (37%)
Query: 100 QPPRRGATPP-----APPRA-PRGAPAAAAAAAP-PPTPAPPPPPAPVAAAAPARAPRAA 152
Q P ATPP +PP + P AP + +A+ P P PPP PV AA + P +
Sbjct: 518 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 577
Query: 153 AAAAT-----APPSPGP--AQPGPRAQRAAPLAAPPP----------------------- 182
A+ T PP+PGP + GPR A PPP
Sbjct: 578 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 637
Query: 183 ---------------APAAPP-----AVAPPAGPRRAPPPAVAAREPPLPPPPQPPAP-- 220
A A+PP A PA R P P +A R P P P PPA
Sbjct: 638 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP 697
Query: 221 --------------PQQQQPPP----PQPQPPPEGGAVRAGGAA-----RPVSLR----- 252
P+ P P P P P GG AG A P R
Sbjct: 698 GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 757
Query: 253 ------EVVRYL--------------GGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRL 292
VV++L GGSGG G G V G AR L L
Sbjct: 758 LGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTG------GARAALSDAEL 811
Query: 293 GALA 296
G A
Sbjct: 812 GRWA 815
Score = 60.5 bits (145), Expect = 4e-09
Identities = 96/355 (27%), Positives = 117/355 (32%), Gaps = 65/355 (18%)
Query: 103 RRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP 162
R A A R P PP +P PPPP P A R AA
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAAL-------RVLGAA------- 50
Query: 163 GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQ---PPA 219
G P A+RA + A P AP AGP R+ ++R P PP A
Sbjct: 51 GAVGRKPLAERAGGIGG-----ATIPESAPRAGPTRS--AGTSSRNPASRPPASGRGERA 103
Query: 220 PPQQQQPPPPQPQPPPEGGAVRAGGAARP---VSLREVV---------RYLGGSGGAGGR 267
PP + P P P G R G + +S E V + S GA R
Sbjct: 104 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA-RR 162
Query: 268 LTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLE 327
T G G A R R T +G LPR PA SARP G + V
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVG---LPR--------PAPSARPRPPTEGPRKSVSS 211
Query: 328 KEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKER---VKEWTPCG 384
E + S G + RPA L+ P S+ R TP
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGL---QRPAS---RSLSSSATPLSSPARSGPSARGTPRA 265
Query: 385 P-HQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPAL 438
P H Q + +G Q + A+ A GP S SP+ P AL
Sbjct: 266 PAHPSQPKPKG-------LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAAL 313
Score = 56.6 bits (135), Expect = 6e-08
Identities = 57/189 (30%), Positives = 69/189 (36%), Gaps = 41/189 (21%)
Query: 79 QRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPA 138
QR R + + AR P RG TP AP + P A PP P A
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARG-TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 139 PVA---AAAPARAPRAAAAAATAPPSPGPAQPGPRA---QRAAPLAAPPPAPAAPPA-VA 191
P +++P P +AA + P PA P + Q A PL P APP+ A
Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL------PLAPPSPSA 347
Query: 192 PPAGPRRAPPPAVAARE-------------------PPL-----PPPPQPPA---PPQQQ 224
PP+ PPA + PPL PPP PPA PP Q
Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407
Query: 225 QPPPPQPQP 233
P PP P
Sbjct: 408 PPSPPASPP 416
Score = 56.2 bits (134), Expect = 7e-08
Identities = 56/240 (23%), Positives = 80/240 (33%), Gaps = 64/240 (26%)
Query: 61 RHGPEPER-TRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAP 119
R GP ++ R E+ + + + ++S P G PA R R A
Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 120 AAAAAAAPPPTPAPPPP------------------PAPVAAAAPA-----RAPRAAAAAA 156
P P+ P PP P+P A P+ + P + + ++
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 157 TAPPSPGPAQPGPRAQRAAPLAAPPPAP-------AAPPAVAPP------------AGPR 197
+A P PA+ GP A+ A P P PP V PP + P
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304
Query: 198 RAPPPAVA--AREPPLPP-------------------PPQPPAPPQQQQPPPPQPQPPPE 236
P P+ A ++ PP P PP P APP Q P P PP +
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 364
Score = 46.2 bits (108), Expect = 8e-05
Identities = 73/268 (27%), Positives = 91/268 (33%), Gaps = 65/268 (24%)
Query: 100 QPPRRGATPPAPPRAPRGAPAAAAAAA------------------PPPTP-APPPPPAPV 140
+PP G+ P PP P AA A P P A P A
Sbjct: 28 RPP--GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85
Query: 141 AAAAPARAPRAAAAAATAPP----SPGP----------AQPGPRAQRAAPLAAPP----- 181
++ PA P A+ APP SPGP +PGP Q+ ++A
Sbjct: 86 SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 145
Query: 182 PAPAAPPAVAPPAGPRR--------APPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQP 233
A AP A AG RR P PA+A R P P P +P+P
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP-----APSARPRP 200
Query: 234 PPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLG 293
P EG ++ +A S E AGG L R + L T L
Sbjct: 201 PTEGPR-KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS---------SATPLS 250
Query: 294 ALALPRGDRPGRAPPAASARPSRSKRGG 321
+ A R R P A A PS+ K G
Sbjct: 251 SPA--RSGPSARGTPRAPAHPSQPKPKG 276
Score = 42.4 bits (98), Expect = 0.001
Identities = 58/232 (25%), Positives = 75/232 (32%), Gaps = 78/232 (33%)
Query: 89 GSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAP--------- 139
G+ +A R P R T P + A A P +P P +P
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
Query: 140 ---------------VAAAAPARAPRAAAAAA-----TAPPSPGPAQPG-PRAQRAA--P 176
VA AP+ +A +A T+ P+PG P R RAA
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 177 LAAPPPAPAAPPAVAPPAGPRRA----------PPPAVAAREP----------------- 209
+ P PAP+A P P GPR++ P A R P
Sbjct: 187 VGLPRPAPSARPR-PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 210 --PLPPP----------PQPPAPPQQQQPP------PPQPQPPPEGGAVRAG 243
PL P P+ PA P Q +P PPQ PP + A G
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
Score = 41.6 bits (96), Expect = 0.002
Identities = 63/254 (24%), Positives = 84/254 (33%), Gaps = 28/254 (11%)
Query: 213 PPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGR 272
P + P + P P+P PP A+R GAA V + + GG GGA
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA-------T 69
Query: 273 VQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSR-SKRGGEERVLEKEEE 331
+ R +R A P R RAPPA + P S G
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 332 EDDDEDEDEEDDVSEG--SEVPE-SDRPAGAQHHQLN---GERGPQSAKERVKEWTPCGP 385
E+ V+ G +E P+ S AGA+ G P A+ T G
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 386 HQGQDEGRGPAPGSGTRQVFSMAAMNKE--------------GGTASVATGPDSPSPVPL 431
+ R P G R+ S A+ + GG A+ S S PL
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 432 PPGKPALPGADGTP 445
+ P A GTP
Sbjct: 250 SSPARSGPSARGTP 263
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 84.0 bits (206), Expect = 3e-16
Identities = 63/192 (32%), Positives = 77/192 (40%), Gaps = 56/192 (29%)
Query: 98 RVQPPRRGATP--------------PAPPRAPRGAPAAAAAAAPPPTP------------ 131
+V PPR+ A P P+ P +P P+ +PP TP
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334
Query: 132 -------APPPPPAPVAAAAPARAPRAAAAAATAPPSPGP-------AQPGPRAQRA--- 174
P PP +P+A P P A APPSP A P P+A A
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394
Query: 175 ----APLAAPP----PAPAAPPA---VAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQ 223
AP + PP AP +PPA V+P A P PP++AA PPL PP PPA P
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA--PPLQVPPSPPASPPM 452
Query: 224 QQPPPPQPQPPP 235
P PQ PP
Sbjct: 453 SPSATPPPQAPP 464
Score = 84.0 bits (206), Expect = 3e-16
Identities = 60/144 (41%), Positives = 73/144 (50%), Gaps = 23/144 (15%)
Query: 109 PAPPRAPRGAPAAAA--AAAPPPTPAPPPPPA-----PVAAAAPARAPRAAA-----AAA 156
P+PP +P P A A A PP APP PPA P+A +P +AP A A A
Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP-QAPNALAVHLLQAPF 401
Query: 157 TAPPSP-------GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREP 209
+ PPSP PA P P + A P + PP+ AAPP PP+ P +PP + +A P
Sbjct: 402 SPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPS-PPASPPMSPSATPP 459
Query: 210 PLPPPPQPPAPPQQQQPPPPQPQP 233
P PPP APP Q PPPQ P
Sbjct: 460 PQAPPPL-AAPPLQLAKPPPQAPP 482
Score = 83.2 bits (204), Expect = 6e-16
Identities = 80/272 (29%), Positives = 106/272 (38%), Gaps = 55/272 (20%)
Query: 4 PPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHG 63
PP + PP AA +SS A+P + + S A P L+ +
Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATP--------SPSAPPSPSAPPSLQTL--------- 315
Query: 64 PEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPA---PPRAPRGAPA 120
P P T L+ ++ S + PP + PPA PP +P
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA--PPALALPPLQAPPSPP 373
Query: 121 AAAAAAPPPTPAP---------------PPPPAPVAAAAPARAPRAAAAAATAPPSPGPA 165
A+ +P TP+P PPP+P P +AP + A+ PS P
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-----PVQAPFSPPASPPVSPSATPP 428
Query: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPL----PPPPQPPA-- 219
P + A PL PP PA+PP P +APPP A PPL PPP PPA
Sbjct: 429 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA---PPLQLAKPPPQAPPALA 485
Query: 220 -PPQQQQPPPPQPQPPPEGGAVRAGGAARPVS 250
PP Q P PP P G A + A+ P+S
Sbjct: 486 TPPLQALPSPPASFP---GQAPFSPSASLPMS 514
Score = 75.9 bits (185), Expect = 9e-14
Identities = 68/218 (31%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 102 PRRGATPPAPPRAPRGAPAAAAA----AAPPPTP-APPPPPAPVAAAAPA-RAPRAAAAA 155
P ATPP+ G+P A +PP +P A PPP AP A A P +AP + A+
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375
Query: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPP 215
P P+ P A L AP P +PP AP + P A PP + PP PP
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP--ASPPVSPSATPPSQAPP 433
Query: 216 QPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQG 275
APP Q PP P PP A A P++ ++ A L +Q
Sbjct: 434 SLAAPPLQV-PPSPPASPPMSPSATPPPQAPPPLA-APPLQLAKPPPQAPPALATPPLQA 491
Query: 276 LLEEEAAARGRLERTRLGALAL-PRGDRPGRAPPAASA 312
L A+ G+ + +L + P P +APP +A
Sbjct: 492 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529
Score = 73.6 bits (179), Expect = 4e-13
Identities = 79/259 (30%), Positives = 101/259 (38%), Gaps = 44/259 (16%)
Query: 1 MAGPPALPPPE--TAAAATTAAAASSSAASPHYQEWI-----------LDTIDSLRSRKA 47
+ PPA PP + T+ + T A S SP L + + S A
Sbjct: 315 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 374
Query: 48 RPDLERICRMVRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGAT 107
P L + P P+ A L+Q + S A PP A+
Sbjct: 375 SPPLSPLAT-------PSPQAPNALAVHLLQ------APFSPPPSPPVQAPFSPP---AS 418
Query: 108 PPAPPRAPRGAPAAAAAAAPP----PTPAPPPPPAPVAAAAPARAPRAAA---AAATAPP 160
PP P A + A + AAPP P+P PP +P A P P AA A PP
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478
Query: 161 SPGPAQPGP--RAQRAAPLAAPPPAPAAPPA---VAPPAGPRRAPPPAVAAREPPLPPPP 215
PA P +A + P + P AP +P A ++P A P PP +AA P L PP
Sbjct: 479 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA--PLLQVPP 536
Query: 216 QPPAPPQQQQP-PPPQPQP 233
PPA P Q P PP P P
Sbjct: 537 SPPASPTLQAPRRPPTPGP 555
Score = 67.8 bits (164), Expect = 2e-11
Identities = 54/164 (32%), Positives = 71/164 (43%), Gaps = 24/164 (14%)
Query: 99 VQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAA---APARAPRAAAAA 155
++PP+ TPP AP P +++ A P APP P AP + +P P + A
Sbjct: 271 LRPPQ--VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATT 328
Query: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPP 215
+ P+ + +PLA PPP APPA+A P P +APP PP PP
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQ--APPALALP--PLQAPP------SPPASPPL 378
Query: 216 QPPAPPQQQQP---------PPPQPQPPPEGGAVRAGGAARPVS 250
P A P Q P P P P P A + A+ PVS
Sbjct: 379 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422
Score = 67.8 bits (164), Expect = 2e-11
Identities = 50/165 (30%), Positives = 62/165 (37%), Gaps = 16/165 (9%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAP-------------AR 147
PP A+PP P A A AAPP A PPP AP A A P +
Sbjct: 443 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 502
Query: 148 APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAR 207
AP + +A+ P P P A L PP PA+P AP P P +V+
Sbjct: 503 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 562
Query: 208 EPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLR 252
L P PP PP + P P+ + + P LR
Sbjct: 563 RLTLALAPGPPPPPSRS---PSSTLSGPDLAGHSSSATSTPEELR 604
Score = 63.9 bits (154), Expect = 3e-10
Identities = 50/146 (34%), Positives = 58/146 (39%), Gaps = 32/146 (21%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPP---PPAPVAAAAPARAPRAAAAAAT 157
PP A P P +P +P + +A PPP APPP PP +A P P A
Sbjct: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQ-APPPLAAPPLQLAKPPPQAPPALATPPLQ 490
Query: 158 APPSPGPAQPG-----PRAQRA-APLAAPPP------------APAAPPAVAPPAGPRRA 199
A PSP + PG P A +PLA PPP P +PPA PRR
Sbjct: 491 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 550
Query: 200 PPPA----------VAAREPPLPPPP 215
P P A P PPPP
Sbjct: 551 PTPGPDTSVSGPRLTLALAPGPPPPP 576
Score = 63.2 bits (152), Expect = 6e-10
Identities = 101/374 (27%), Positives = 121/374 (32%), Gaps = 76/374 (20%)
Query: 103 RRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP 162
R A A R P PP +P PPPP P A R AA
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAAL-------RVLGAA------- 50
Query: 163 GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQ 222
G P A+RA + A P AP AGP R P + R APP
Sbjct: 51 GAVGRKPLAERAGGIGG-----ATIPESAPRAGPTRTSRPPASGR--------GERAPPA 97
Query: 223 QQQPPPPQPQPPPEGGAVRAGGAARP---VSLREVV---------RYLGGSGGAGGRLTR 270
+ P P P G R G + +S E V + S GA R T
Sbjct: 98 KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA-RRDTS 156
Query: 271 GRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEE 330
G G A R R T +G LPR PA SARP G + V E
Sbjct: 157 GPTPGTPSPAMARRSRAAGTEVG---LPR--------PAPSARPRPPTEGPRKSVSSASE 205
Query: 331 EEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKER---VKEWTPCGP-H 386
+ S G + RPA L+ P S+ R TP P H
Sbjct: 206 HSTTEPSPAARRRPSAGGGL---QRPAS---RSLSSSATPLSSPARSGPSARGTPRAPAH 259
Query: 387 QGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLP-PGKPALPGADGTP 445
Q + +G Q + A+ A GP S SP+ P P P P A
Sbjct: 260 PSQPKPKG-------LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA---- 308
Query: 446 FGCPPGRKEKPSDP 459
PP + PS P
Sbjct: 309 ---PPSLQTLPSPP 319
Score = 63.2 bits (152), Expect = 6e-10
Identities = 53/210 (25%), Positives = 74/210 (35%), Gaps = 34/210 (16%)
Query: 61 RHGPEPER-TRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAP 119
R GP ++ R E+ + + + ++S P G PA R R A
Sbjct: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 175
Query: 120 AAAAAAAPPPTPAPPPP------------------PAPVAAAAPA-----RAPRAAAAAA 156
P P+ P PP P+P A P+ + P + + ++
Sbjct: 176 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235
Query: 157 TAPPSPGPAQPGPRAQRAAPLAAPPPAP-------AAPPAVAPP---AGPRRAPPPAVAA 206
+A P PA+ GP A+ A P P PP V PP A P P +
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 295
Query: 207 REPPLPPPPQPPAPPQQQQPPPPQPQPPPE 236
P PP P APP Q P P PP +
Sbjct: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325
Score = 61.2 bits (147), Expect = 2e-09
Identities = 85/304 (27%), Positives = 100/304 (32%), Gaps = 113/304 (37%)
Query: 100 QPPRRGATPP-----APPRA-PRGAPAAAAAAAP-PPTPAPPPPPAPVAAAAPARAPRAA 152
Q P ATPP +PP + P AP + +A+ P P PPP PV AA + P +
Sbjct: 479 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538
Query: 153 AAAAT-----APPSPGP--AQPGPRAQRAAPLAAPPP----------------------- 182
A+ T PP+PGP + GPR A PPP
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 598
Query: 183 ---------------APAAPP-----AVAPPAGPRRAPPPAVAAREPPLPPPPQPPAP-- 220
A A+PP A PA R P P +A R P P P PPA
Sbjct: 599 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP 658
Query: 221 --------------PQQQQPPP----PQPQPPPEGGAVRAGGAA-----RPVSLR----- 252
P+ P P P P P GG AG A P R
Sbjct: 659 GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 718
Query: 253 ------EVVRYL--------------GGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRL 292
VV++L GGSGG G G V G AR L L
Sbjct: 719 LGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTG------GARAALSDAEL 772
Query: 293 GALA 296
G A
Sbjct: 773 GRWA 776
Score = 58.9 bits (141), Expect = 1e-08
Identities = 49/166 (29%), Positives = 61/166 (36%), Gaps = 50/166 (30%)
Query: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA 165
ATP + P A + +A P PA P P P A R P+ A P+ GP
Sbjct: 237 ATPLSSP-----ARSGPSARGTPRAPAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPL 290
Query: 166 QPGPRAQRAAPLAAP----PPAPAAPPAV------------------------------- 190
++PLA P PP+P+APP++
Sbjct: 291 S-------SSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343
Query: 191 APPAGPRRAPPPAV--AAREPPLPPPPQPPAPPQQQQPPPPQPQPP 234
+PP P PPP A PPL PP PPA P P PQ P
Sbjct: 344 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 389
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 83.6 bits (205), Expect = 4e-16
Identities = 58/167 (34%), Positives = 65/167 (38%), Gaps = 27/167 (16%)
Query: 94 RNAARVQPPRRGATPPA--PPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRA 151
R + P R P+ PP P G+P PP PAPPPPP P+ P
Sbjct: 282 RGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPP-PAPPPPPPPMIGIPPP----- 335
Query: 152 AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPL 211
PP G PG P +PP P P APP PPP AA P L
Sbjct: 336 -------PPPVGFGSPG-----TPPPPSPPSFPPHPDFAAPPP-----PPPPPAADYPTL 378
Query: 212 PPPP--QPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVR 256
PPPP QP PPPP P PPP G A P L + +
Sbjct: 379 PPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTK 425
Score = 72.4 bits (176), Expect = 1e-12
Identities = 59/220 (26%), Positives = 91/220 (41%), Gaps = 23/220 (10%)
Query: 31 YQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPERTRAEL-------EKLIQQRAVL 83
++E +L + K + E+ R P +TR E ++ ++ + L
Sbjct: 160 WKEKMLQDTKDIMKEKRKHRKEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKL 219
Query: 84 RVS-YKGSISYRNAAR--VQPPRRGATPPAPPRAPRGAPAAAAAAAP-PPTPAPPPPPAP 139
S Y ++ Y+N + V+ + PP P +P+ + + PP PA P
Sbjct: 220 GTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVD 279
Query: 140 VAAAAPARAPRAAAAAATAPPSPGP---AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGP 196
+ P+ ++ + + P P P + PGP+ A P A PPP PP + P
Sbjct: 280 NQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPP---PPPMIGIP--- 333
Query: 197 RRAPPPAVAAREPPLPPPPQPPA-PPQQQQPPPPQPQPPP 235
PPP V P PPPP PP+ PP PP P PPP
Sbjct: 334 --PPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPP 371
Score = 61.2 bits (147), Expect = 2e-09
Identities = 48/137 (35%), Positives = 52/137 (37%), Gaps = 29/137 (21%)
Query: 102 PRRG-ATPPAPPRAPRGAPAAAAAAAPPPT--------PAPPP---PPAPVAAAAPARAP 149
P+ G A PPAPP P P PPP P P P PP P AA P P
Sbjct: 312 PKPGFAPPPAPPPPP--PPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPP 369
Query: 150 RAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREP 209
AA T PP P G APPP P PP PP PP A +P
Sbjct: 370 PPAADYPTLPPPPLSQPTG---------GAPPPPPPPPPPGPPP------PPFTGADGQP 414
Query: 210 PLPPPPQPPAPPQQQQP 226
+PPP P+ P
Sbjct: 415 AIPPPLSDTTKPKSSLP 431
Score = 54.3 bits (129), Expect = 3e-07
Identities = 37/118 (31%), Positives = 42/118 (35%), Gaps = 18/118 (15%)
Query: 101 PPRRGATPPAPP-----------RAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAP 149
PP G PP PP +P P AAPPP P PP P P P
Sbjct: 327 PPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQP 386
Query: 150 RAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAR 207
A PP P P PGP P PA PP ++ P+ + P AR
Sbjct: 387 TGGA----PPPPPPPPPPGP---PPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDAR 437
Score = 43.1 bits (100), Expect = 6e-04
Identities = 25/71 (35%), Positives = 27/71 (38%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP 160
PP A P P P P A PPP P P PPP P A A + T P
Sbjct: 368 PPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPK 427
Query: 161 SPGPAQPGPRA 171
S PA R+
Sbjct: 428 SSLPAVSDARS 438
Score = 33.5 bits (75), Expect = 0.50
Identities = 20/58 (34%), Positives = 25/58 (43%), Gaps = 6/58 (10%)
Query: 102 PRRGATPPAPPRAPRGAP------AAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAA 153
P GA PP PP P G P A A PPP P + + A + AR+ +A
Sbjct: 386 PTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSA 443
Score = 30.4 bits (67), Expect = 4.3
Identities = 16/31 (51%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 422 GPDSPSPVPLPPGKPALP--GADGTPFGCPP 450
G P P P PPG P P GADG P PP
Sbjct: 389 GAPPPPPPPPPPGPPPPPFTGADGQPAIPPP 419
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 83.2 bits (204), Expect = 6e-16
Identities = 59/157 (37%), Positives = 67/157 (42%), Gaps = 20/157 (12%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPA----PPPPPAPVAAAAPARAPRAAAAAA 156
P + G PP PP P PPP PPP P P P P+ ++
Sbjct: 51 PGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPV 110
Query: 157 TAPPSPGPAQPG----PRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLP 212
A PGPA PG P A +AP A PP APP P GP PPPAV + PP
Sbjct: 111 VA-QGPGPA-PGVGSAPPASSSAP-PATPPTSGAPPGSGP--GPTPTPPPAVTS-APPGA 164
Query: 213 PPPQPPA------PPQQQQPPPPQPQPPPEGGAVRAG 243
PPP PP+ PPQ PPPP P G + G
Sbjct: 165 PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQG 201
Score = 73.6 bits (179), Expect = 4e-13
Identities = 63/198 (31%), Positives = 73/198 (36%), Gaps = 34/198 (17%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTP--------APPPPPAPVAAAAP---ARAP 149
PP++ PP P P PPP P A P PAP +AP + AP
Sbjct: 73 PPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAP 132
Query: 150 RAAAAAATAPPSPGPAQ---PGPRAQRAAPLAAPPPAPAA-PPAVAPPAGPRRAPPPAVA 205
A + APP GP P P A P A PP P++ P P AG PPP A
Sbjct: 133 PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAG---GPPPPPA 189
Query: 206 AREPPLPPPPQPPAP--------PQQQQP--------PPPQPQPPPEGGAVRAGGAARPV 249
A P P P Q P P P +P P P+PP GG GG
Sbjct: 190 AVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP 249
Query: 250 SLREVVRYLGGSGGAGGR 267
+ GG GGR
Sbjct: 250 PYHQQHHQGPPPGGPGGR 267
Score = 67.8 bits (164), Expect = 2e-11
Identities = 45/136 (33%), Positives = 53/136 (38%), Gaps = 5/136 (3%)
Query: 95 NAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAA 154
+A PP GA P + P P P A +APP P P PP + V P
Sbjct: 130 SAPPATPPTSGAPPGSGP-GPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188
Query: 155 AATAPPSPGPAQ-PGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP 213
AA P PGP Q PGP + + P P P ++ P G PP EP
Sbjct: 189 AAVPGPGPGPKQGPGPGGPKGGKMPG-GPKPGGGPGLSTPGG--HPKPPHRGGGEPRGGR 245
Query: 214 PPQPPAPPQQQQPPPP 229
PP Q Q PPP
Sbjct: 246 QHHPPYHQQHHQGPPP 261
Score = 66.2 bits (160), Expect = 7e-11
Identities = 52/166 (31%), Positives = 57/166 (34%), Gaps = 25/166 (15%)
Query: 98 RVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTP----APPPPPAPVAAAAPARAPRAAA 153
R PP G P P + PPP P PPP P P P
Sbjct: 32 RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQP---- 87
Query: 154 AAATAPPSPGPAQ----PGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPP--PAVAAR 207
PP P P Q P P + P+ A P PA APPA APP P +
Sbjct: 88 -----PPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSS-APPATPPTSGA 141
Query: 208 EPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAV-----RAGGAARP 248
P P P P PP PP P P P V +AGG P
Sbjct: 142 PPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPP 187
Score = 50.4 bits (119), Expect = 4e-06
Identities = 36/96 (37%), Positives = 39/96 (40%), Gaps = 17/96 (17%)
Query: 159 PPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPP 218
P PGP Q GP+ PPP P PP P PP P PPP P
Sbjct: 46 PMGPGPGQSGPKPP------IPPPPPHQQQQQPPPQQP---PPQQPP----PHQPPPHPQ 92
Query: 219 APPQQQQPPPPQPQPPP---EG-GAVRAGGAARPVS 250
QQQ PPPPQ P +G G G+A P S
Sbjct: 93 PHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPAS 128
Score = 34.7 bits (78), Expect = 0.23
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 6/60 (10%)
Query: 391 EGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPALPGADGTPFGCPP 450
+G GPAPG G+ S +A T+ G P P P PP P P G PP
Sbjct: 113 QGPGPAPGVGSAPPASSSAPPATPPTSGAPPG-SGPGPTPTPP-----PAVTSAPPGAPP 166
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 82.4 bits (202), Expect = 9e-16
Identities = 67/200 (33%), Positives = 80/200 (40%), Gaps = 41/200 (20%)
Query: 65 EPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPR---RGATPPAPPRA------- 114
E + E+ KL ++ L + K S AA PP R PPAPP
Sbjct: 531 EVSQLTGEVAKLTKE---LEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTII 587
Query: 115 -PRGAPAAAAAAAPPPTPAPPPPPAP--VAAAAPARAPRAAAAAATAPPSPGPAQPGPRA 171
P AP + PPP P PPPPP P V ++P P A + PP G A P
Sbjct: 588 PPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLP-GGTAISPPPPLSGDATIPP-- 644
Query: 172 QRAAPLAAPPPAPAAPPAVAP---PAGPRRAPPPAV--AAREPPLP---------PPPQP 217
PPP P +P P G PPP + +AR PP P PPP P
Sbjct: 645 --------PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPP 696
Query: 218 PAPPQQQQPPPPQPQPPPEG 237
P P + PPPP P P G
Sbjct: 697 PLPGEAGMPPPPPPLPGGPG 716
Score = 71.6 bits (174), Expect = 2e-12
Identities = 47/149 (31%), Positives = 57/149 (38%), Gaps = 7/149 (4%)
Query: 85 VSYKGSISYRNAARVQPPRRG-ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAA 143
+S S+ A PP G AT P PP P G + ++ P T PPPPP P +A
Sbjct: 618 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 677
Query: 144 APARAPRAAAAAATAPPSP------GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPR 197
P P +A PP P G P P + PPP P P PP G
Sbjct: 678 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 737
Query: 198 RAPPPAVAAREPPLPPPPQPPAPPQQQQP 226
PPP P P P P + +P
Sbjct: 738 MPPPPPFGFGVPAAPVLPFGLTPKKLYKP 766
Score = 54.7 bits (130), Expect = 2e-07
Identities = 39/128 (30%), Positives = 47/128 (36%), Gaps = 25/128 (19%)
Query: 120 AAAAAAAPPPTPAPPP-PPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLA 178
+AAA PP P+ P PPAP P + PP P P
Sbjct: 557 SAAAITVPPSVPSRAPVPPAP---------PLPGDSGTIIPPPPAPGDS---------TT 598
Query: 179 APPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQ------PPAPPQQQQPPPPQPQ 232
PPP P PP P G + PP++ PPPP PP PP + P P
Sbjct: 599 PPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 658
Query: 233 PPPEGGAV 240
P G A+
Sbjct: 659 SLPGGTAI 666
Score = 46.6 bits (109), Expect = 6e-05
Identities = 38/118 (32%), Positives = 42/118 (35%), Gaps = 23/118 (19%)
Query: 101 PPRRGAT--PPAPPRAPRGAPAAAAAAAPPPTPA-----PPPPPAPVAAAAPARAPRAAA 153
PP G+ PP PP P +A PPP P PPPPP P P P
Sbjct: 670 PPLPGSARIPPPPPPLPG---SAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPP-PPPFPG 725
Query: 154 AAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAG--PRRAPPPAVAAREP 209
PP PG P P PP P A P G P++ P V R P
Sbjct: 726 GPGIPPPPPGMGMPPP----------PPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 773
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/66 (42%), Positives = 30/66 (45%), Gaps = 13/66 (19%)
Query: 185 AAPPAVAPPAGPRRAP-PPAVAAREPPLPPP-----PQPPAPPQQQQPPPPQPQPPPEGG 238
+A PP+ P RAP PPA PPLP P PPAP PPP P PPP
Sbjct: 557 SAAAITVPPSVPSRAPVPPA-----PPLPGDSGTIIPPPPAPGDSTTPPP--PPPPPPPP 609
Query: 239 AVRAGG 244
GG
Sbjct: 610 PPLPGG 615
Score = 32.3 bits (72), Expect = 1.1
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 417 ASVATGPDSPSPVPLPPGKPALPGADGTPFGCPPGRKEKPSDP 459
A++ P PS P+PP P LPG GT PP + + P
Sbjct: 559 AAITVPPSVPSRAPVPPAPP-LPGDSGTIIPPPPAPGDSTTPP 600
Score = 31.2 bits (69), Expect = 2.5
Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 3/48 (6%)
Query: 414 GGTASVATGPDSPSPVPLPPGKPALPGADGTPFGCP--PGRKEKPSDP 459
GGTA + P P +PP P LPG+ G P P PG P P
Sbjct: 662 GGTA-IPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP 708
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 82.4 bits (202), Expect = 9e-16
Identities = 67/200 (33%), Positives = 80/200 (40%), Gaps = 41/200 (20%)
Query: 65 EPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPR---RGATPPAPPRA------- 114
E + E+ KL ++ L + K S AA PP R PPAPP
Sbjct: 540 EVSQLTGEVAKLTKE---LEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTII 596
Query: 115 -PRGAPAAAAAAAPPPTPAPPPPPAP--VAAAAPARAPRAAAAAATAPPSPGPAQPGPRA 171
P AP + PPP P PPPPP P V ++P P A + PP G A P
Sbjct: 597 PPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLP-GGTAISPPPPLSGDATIPP-- 653
Query: 172 QRAAPLAAPPPAPAAPPAVAP---PAGPRRAPPPAV--AAREPPLP---------PPPQP 217
PPP P +P P G PPP + +AR PP P PPP P
Sbjct: 654 --------PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPP 705
Query: 218 PAPPQQQQPPPPQPQPPPEG 237
P P + PPPP P P G
Sbjct: 706 PLPGEAGMPPPPPPLPGGPG 725
Score = 71.6 bits (174), Expect = 2e-12
Identities = 47/149 (31%), Positives = 57/149 (38%), Gaps = 7/149 (4%)
Query: 85 VSYKGSISYRNAARVQPPRRG-ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAA 143
+S S+ A PP G AT P PP P G + ++ P T PPPPP P +A
Sbjct: 627 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 686
Query: 144 APARAPRAAAAAATAPPSP------GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPR 197
P P +A PP P G P P + PPP P P PP G
Sbjct: 687 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 746
Query: 198 RAPPPAVAAREPPLPPPPQPPAPPQQQQP 226
PPP P P P P + +P
Sbjct: 747 MPPPPPFGFGVPAAPVLPFGLTPKKLYKP 775
Score = 54.7 bits (130), Expect = 2e-07
Identities = 39/128 (30%), Positives = 47/128 (36%), Gaps = 25/128 (19%)
Query: 120 AAAAAAAPPPTPAPPP-PPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLA 178
+AAA PP P+ P PPAP P + PP P P
Sbjct: 566 SAAAITVPPSVPSRAPVPPAP---------PLPGDSGTIIPPPPAPGDS---------TT 607
Query: 179 APPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQ------PPAPPQQQQPPPPQPQ 232
PPP P PP P G + PP++ PPPP PP PP + P P
Sbjct: 608 PPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 667
Query: 233 PPPEGGAV 240
P G A+
Sbjct: 668 SLPGGTAI 675
Score = 46.6 bits (109), Expect = 6e-05
Identities = 38/118 (32%), Positives = 42/118 (35%), Gaps = 23/118 (19%)
Query: 101 PPRRGAT--PPAPPRAPRGAPAAAAAAAPPPTPA-----PPPPPAPVAAAAPARAPRAAA 153
PP G+ PP PP P +A PPP P PPPPP P P P
Sbjct: 679 PPLPGSARIPPPPPPLPG---SAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPP-PPPFPG 734
Query: 154 AAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAG--PRRAPPPAVAAREP 209
PP PG P P PP P A P G P++ P V R P
Sbjct: 735 GPGIPPPPPGMGMPPP----------PPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 782
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/66 (42%), Positives = 30/66 (45%), Gaps = 13/66 (19%)
Query: 185 AAPPAVAPPAGPRRAP-PPAVAAREPPLPPP-----PQPPAPPQQQQPPPPQPQPPPEGG 238
+A PP+ P RAP PPA PPLP P PPAP PPP P PPP
Sbjct: 566 SAAAITVPPSVPSRAPVPPA-----PPLPGDSGTIIPPPPAPGDSTTPPP--PPPPPPPP 618
Query: 239 AVRAGG 244
GG
Sbjct: 619 PPLPGG 624
Score = 32.3 bits (72), Expect = 1.1
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 417 ASVATGPDSPSPVPLPPGKPALPGADGTPFGCPPGRKEKPSDP 459
A++ P PS P+PP P LPG GT PP + + P
Sbjct: 568 AAITVPPSVPSRAPVPPAPP-LPGDSGTIIPPPPAPGDSTTPP 609
Score = 31.2 bits (69), Expect = 2.5
Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 3/48 (6%)
Query: 414 GGTASVATGPDSPSPVPLPPGKPALPGADGTPFGCP--PGRKEKPSDP 459
GGTA + P P +PP P LPG+ G P P PG P P
Sbjct: 671 GGTA-IPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPP 717
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 82.4 bits (202), Expect = 9e-16
Identities = 78/231 (33%), Positives = 85/231 (36%), Gaps = 52/231 (22%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP 160
PP GA P P AP PAA A AAP P PPPPPAP A P P AA A P
Sbjct: 241 PPFVGAAAPPAPAAP-SPPAAPAPAAPAAAP-PPPPPAPATLARPPGHPAGPPTAAPAVP 298
Query: 161 SPGPAQPGPRAQRAAPLAAPPPAPAA--PPAVAPPAGP---RRAPPPAVAAREPPLPPPP 215
P AQ G A AAP PAPAA P V+ GP AP P V A P
Sbjct: 299 PPAAAQNGGSAG-----AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQA 353
Query: 216 QPPA-------------------PPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVR 256
PPA P Q P P PPP G P L +
Sbjct: 354 APPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT--------PTGLPK--- 402
Query: 257 YLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAP 307
GA G +T Q L A + T + PR +P + P
Sbjct: 403 ------GAAGAVT----QSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
Score = 80.9 bits (198), Expect = 3e-15
Identities = 71/217 (32%), Positives = 82/217 (37%), Gaps = 56/217 (25%)
Query: 96 AARVQPPRRGAT------------------PPAPPRAPRGAPAAAAAAAPPPTPAPPPPP 137
AA+++PP G+ PA P P G A AA A P P P P P P
Sbjct: 123 AAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGP 182
Query: 138 APV--------------AAAAPARAPRAAAAA--------ATAPPSPGPAQPGPRAQRAA 175
P +AA + AAA A A P P PA PG Q
Sbjct: 183 GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPP 242
Query: 176 PL-AAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP----PPQPPAPPQQQQPPPPQ 230
+ AA PPAPAAP +PPA P A P A PP P PP PA P P P
Sbjct: 243 FVGAAAPPAPAAP---SPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPP 299
Query: 231 PQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGR 267
P GG+ A A P + GG G G+
Sbjct: 300 PAAAQNGGSAGAAPAPAPAA--------GGPAGVSGQ 328
Score = 80.1 bits (196), Expect = 5e-15
Identities = 73/224 (32%), Positives = 78/224 (34%), Gaps = 59/224 (26%)
Query: 96 AARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA 155
A R +P G P PP R P A APP PPP + AP P AAA A
Sbjct: 92 AGRARPGGGGPQRPGPPSPRR--PLVPAGPAPPAAKLRPPPEGSAGSCAPV--PAAAAVA 147
Query: 156 ATAPPSP-GPAQP-GP--RAQRAAPLAAPPPAPAAPPAVAPPAGPRRA------------ 199
A P+P GPA+P GP A RA P P P P P PAGP A
Sbjct: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207
Query: 200 --------------------------------PPPAVAAREPPLPPPPQPPAPPQQQQP- 226
PP V A PP P P PPA P P
Sbjct: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA 267
Query: 227 -PPPQPQPPPEGGAVRAGGAARPVSLREVV-----RYLGGSGGA 264
PP P P P A G A P + V GGS GA
Sbjct: 268 AAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGA 311
Score = 73.9 bits (180), Expect = 3e-13
Identities = 101/374 (27%), Positives = 127/374 (33%), Gaps = 49/374 (13%)
Query: 112 PRAPRGAPAAAAA-----AAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQ 166
PR P AAA A + P A PA A AP AP A P GP +
Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104
Query: 167 PGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRR--APPP---AVAAREPPLPPPPQPPAPP 221
PGP + R PL PAP A PP G AP P AVAA P P P PA P
Sbjct: 105 PGPPSPR-RPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGP 163
Query: 222 -----QQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAG---GRLTRGRV 273
+ P P P P P G + G +L L A + G
Sbjct: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223
Query: 274 QGLLEEEAAARGRLERTR--LGAL-----------ALPRGDRPGRAPPAASARPSRSKRG 320
L + AA G + +T +GA A P P APP P+ R
Sbjct: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARP 283
Query: 321 GEERVLEKEEEEDDDEDEDEEDDVSEG---SEVPESDRPAGAQHHQLNGERGPQSAKERV 377
++ S G + P + PAG ++G+ GP +A
Sbjct: 284 PGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAG-----VSGQPGPGAAAAAP 338
Query: 378 KEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPA 437
+ + PA ++AA AS+ GP +P P P
Sbjct: 339 APGVKAESPKRVVQAAPPA-------AQTLAASGPASTAASMVIGPTMQGALPSPAAVP- 390
Query: 438 LPGADGTPFGCPPG 451
P A GTP G P G
Sbjct: 391 -PPAPGTPTGLPKG 403
Score = 68.6 bits (166), Expect = 1e-11
Identities = 68/217 (31%), Positives = 80/217 (36%), Gaps = 29/217 (13%)
Query: 108 PPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP 167
P AP + P AAA PP PA P PPA A AAPA AP PP P PA
Sbjct: 231 PAAPGTVIQTPPFVGAAA--PPAPAAPSPPAAPAPAAPAAAP--------PPPPPAPAT- 279
Query: 168 GPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPP 227
LA PP PA PP AP P A +A P P P QP
Sbjct: 280 ---------LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG 330
Query: 228 PPQPQPPPEGGAVRAGGAARPVS----LREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAA 283
P P G V+A R V + + G + A + +QG L AA
Sbjct: 331 PGAAAAAPAPG-VKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAV 389
Query: 284 RGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRG 320
T G LP+G G + S P+ + G
Sbjct: 390 PPPAPGTPTG---LPKG-AAGAVTQSLSRTPTATTSG 422
Score = 63.9 bits (154), Expect = 3e-10
Identities = 65/189 (34%), Positives = 70/189 (37%), Gaps = 59/189 (31%)
Query: 96 AARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPP-----------TPAPPP--------- 135
AA PP AT PP P G P AA A PPP PAP P
Sbjct: 268 AAPPPPPPAPATLARPPGHPAGPPTAAP-AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVS 326
Query: 136 -PPAPVAAAA----------PARAPRAAAAAATAPPSPGPAQP------GPRAQRA--AP 176
P P AAAA P R +AA AA + GPA GP Q A +P
Sbjct: 327 GQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSP 386
Query: 177 LAAPPPAPAAPPAV-----------------APPAGPRRAPPPAVAAREPPLPPPPQPPA 219
A PPPAP P + A +G R P V A P LP PPQ P
Sbjct: 387 AAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLA--PRLPQPPQNPT 444
Query: 220 PPQQQQPPP 228
Q Q PP
Sbjct: 445 NIQNFQLPP 453
Score = 33.9 bits (76), Expect = 0.39
Identities = 50/192 (26%), Positives = 60/192 (31%), Gaps = 56/192 (29%)
Query: 102 PRRGATPPAPPRAPRGAPAAAAAAAP------------------------PPTPAPPP-- 135
P A PP P P G P AA A P P PP
Sbjct: 384 PSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
Query: 136 --------PPAPVAAAA--------PARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAA 179
PP V + P +A A A A P A P P A P +A
Sbjct: 444 TNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMA-PRP----ATPTSA 498
Query: 180 PPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGA 239
PP + A P R+ P + + QP A Q+ P QPQ
Sbjct: 499 PPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSA--TLQRSPGVQPQ------- 549
Query: 240 VRAGGAARPVSL 251
+ GGAA+ SL
Sbjct: 550 LVLGGAAQTASL 561
Score = 30.4 bits (67), Expect = 4.3
Identities = 42/162 (25%), Positives = 49/162 (30%), Gaps = 27/162 (16%)
Query: 304 GRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQ 363
G APPAA RP G V + V PA A +
Sbjct: 118 GPAPPAAKLRPPPEGSAGSCA------------------PVPAAAAVAAGPEPAPAGPAK 159
Query: 364 LNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVF--SMAAMNKEGGTASVAT 421
GP + R GP G G G G G Q S A +N A +
Sbjct: 160 ---PAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVS 216
Query: 422 GPDSPSPVPLPPGKPALPGA--DGTPF--GCPPGRKEKPSDP 459
++ LP KPA PG PF P PS P
Sbjct: 217 LVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPP 258
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 82.4 bits (202), Expect = 9e-16
Identities = 55/161 (34%), Positives = 63/161 (39%), Gaps = 26/161 (16%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPA---------------PPPPPAPVAAAAP 145
PP+ T PAP AP AA P PTP PP PP P P
Sbjct: 778 PPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP 837
Query: 146 ARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPA--APPAVAPPAGPRRAPPPA 203
P+ + A PPSP P Q A+ PP PA + P PA PPA
Sbjct: 838 PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPA 897
Query: 204 VAAREP------PLPPPPQPPAPPQQQ---QPPPPQPQPPP 235
V A+ P+P P PP PP+ PPPP P P P
Sbjct: 898 VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938
Score = 80.9 bits (198), Expect = 3e-15
Identities = 61/208 (29%), Positives = 74/208 (35%), Gaps = 60/208 (28%)
Query: 102 PRRGATPPAPPRAPRGAPAAAAA--------------AAPPP-------------TPAPP 134
P G PP PP P P +A A +APPP P P
Sbjct: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP 763
Query: 135 PPPAPVAAAAPARAPR---------------AAAAAATAPPSPGPAQPGPRAQRAAPLAA 179
PPP P+ A P +AP A APP+P P P + Q A P +
Sbjct: 764 PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASY 823
Query: 180 PPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLP----------------PPPQPPAPPQQ 223
PP+P PP PP P + A+ PP P PPP PPA Q
Sbjct: 824 IPPSPPTPPVPVPP--PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ 881
Query: 224 QQPPPPQPQPPPEGGAVRAGGAARPVSL 251
P P P AV+A +P S+
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSI 909
Score = 67.4 bits (163), Expect = 3e-11
Identities = 49/156 (31%), Positives = 61/156 (39%), Gaps = 32/156 (20%)
Query: 97 ARVQPPRRGATPPAPPRAPRG---APAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAA 153
AR++ R T PP +P+ P A+ +PP P PPPPP P P
Sbjct: 593 ARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP-------- 644
Query: 154 AAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP 213
PP P P+Q P A AAP+ + +G A +PP PP
Sbjct: 645 -----PPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSG---------ALFKPPTPP 690
Query: 214 -------PPQPPAPPQQQQPPPPQPQPPPEGGAVRA 242
PQ PP PPPP P PPP G+ A
Sbjct: 691 VMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA 726
Score = 67.0 bits (162), Expect = 4e-11
Identities = 59/204 (28%), Positives = 64/204 (31%), Gaps = 71/204 (34%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAA----------------------PPPTPA------ 132
PP PP PP + AP+A +AA PPTP
Sbjct: 637 PPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQS 696
Query: 133 --------------PPPPPAPVAAAAPARAPRAAAAAA------TAPPSP---------- 162
PPPPP P A A A A +APP P
Sbjct: 697 VKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHIT 756
Query: 163 --GPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAP 220
P P P APL PP AP P P + P V PP P PP PPA
Sbjct: 757 QVAPPTPPPPPPIPAPL--PPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK 814
Query: 221 PQ---------QQQPPPPQPQPPP 235
Q P PP P PPP
Sbjct: 815 KQPAFPASYIPPSPPTPPVPVPPP 838
Score = 62.8 bits (151), Expect = 8e-10
Identities = 46/166 (27%), Positives = 67/166 (40%), Gaps = 19/166 (11%)
Query: 97 ARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPA----PPPPPAPVAAAAPARAPRAA 152
A V P A P P P + PPP + PPPPP+PV A P P
Sbjct: 888 ANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPP--- 944
Query: 153 AAAATAPPSPGPA-QPGPRAQRAAPLAA--PPPAPAAPPAVAPPAGPRRAPP--PAVAAR 207
TA P+P + PG + + + PPP P ++ +G P P+V +
Sbjct: 945 ----TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000
Query: 208 EPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLRE 253
PP + +P ++ PP P PP+ G + G P L++
Sbjct: 1001 VSKFTPPAESGSPSKETLPP---PAAPPKPGKLNLSGVNLPGVLQQ 1043
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/165 (27%), Positives = 62/165 (37%), Gaps = 31/165 (18%)
Query: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPP--------PPPAPVAAAAPARAPRAAAAAAT 157
A PP P +P + A+ PP P PP P PA VA +P +
Sbjct: 848 AKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPS 907
Query: 158 APPSPGPAQPGPRAQRAAPLAAPPPAPA-APPAVAPPAG---PRRAPPPAVAAREPPLPP 213
+ P P P P P + + PPP+P APP PP P ++ P + P
Sbjct: 908 SIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPG 967
Query: 214 PPQPPAPPQQ----------QQPPPPQPQ---------PPPEGGA 239
+PP PQ+ + P P +P PP E G+
Sbjct: 968 GKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGS 1012
Score = 54.3 bits (129), Expect = 3e-07
Identities = 38/133 (28%), Positives = 52/133 (39%), Gaps = 12/133 (9%)
Query: 182 PAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVR 241
P + P ++P P+ P + PPLPPPP PP PP PPPP P P P A
Sbjct: 601 PYTSLVPPLSPQ--PKIVTPYTASQPSPPLPPPPPPPPPPPP--PPPPPPPPLPSQSAPS 656
Query: 242 AGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGD 301
AG AA + L + G L + +++ ++ + L P G
Sbjct: 657 AGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQS--------VKPQILVPPNGV 708
Query: 302 RPGRAPPAASARP 314
P PP P
Sbjct: 709 VPPPPPPPPPPTP 721
Score = 32.7 bits (73), Expect = 0.86
Identities = 53/245 (21%), Positives = 78/245 (31%), Gaps = 37/245 (15%)
Query: 5 PALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGP 64
PA PPP A+ T + S S +K P +R +
Sbjct: 936 PAPPPPPPPTASPTPDKSGSPGKKT-------SKTSSPGGKKPPPTPQRNSSIKSSSGAE 988
Query: 65 EPERTRAELEKLIQQRAVLRVSYKGSISYRNAAR-VQPPRRG-----------------A 106
PE R ++ L+ + S GS S PP+ G
Sbjct: 989 HPEPKRPSVDSLVSKFTPPAES--GSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCV 1046
Query: 107 TPPAPPRAPRGAPAAAAAAAPPP-TPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA 165
+ AP + RG + +PP + PPPPP P P A + SP A
Sbjct: 1047 SAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIP----AVFSGNTSPKVA 1102
Query: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP-PPQPPAPPQQQ 224
P+ Q+ + ++ APP P A + +P + PQ P P+
Sbjct: 1103 VVNPQPQQWSKMS----VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSS 1158
Query: 225 QPPPP 229
P
Sbjct: 1159 LSVQP 1163
Score = 30.8 bits (68), Expect = 3.3
Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 417 ASVATGPDSPSPVPLPPGKPALPGADGTP--FGCPPGRKEKPSDP 459
+S+ P PSPVP PP P P A TP G P + K S P
Sbjct: 923 SSLVFPPPPPSPVPAPPPPPP-PTASPTPDKSGSPGKKTSKTSSP 966
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 82.4 bits (202), Expect = 9e-16
Identities = 61/194 (31%), Positives = 81/194 (41%), Gaps = 14/194 (7%)
Query: 63 GPEPERTRAELEKLIQQRAVLRVSYKGS-----ISYRNAARVQPPRRGATPPAPPRAPRG 117
GP P+R L++ + +S G + R + P++ A+ APP +G
Sbjct: 471 GPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQG 530
Query: 118 APAAAAAAAP--PPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAA 175
+ A P PP PP P+P A P +A R + + APP A PG + ++
Sbjct: 531 RQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP 590
Query: 176 PLAAPPPAPAAPPAVAPPAGP-RRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPP 234
P PP PA P A AGP R PP P P P P P Q+ P Q PP
Sbjct: 591 P--QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQK--PSQDVPP 646
Query: 235 PEGGAVRAGGAARP 248
P A AGG P
Sbjct: 647 PATAA--AGGPPHP 658
Score = 65.5 bits (158), Expect = 1e-10
Identities = 56/175 (32%), Positives = 72/175 (41%), Gaps = 36/175 (20%)
Query: 100 QPPRRGATPPA----PPRAPRGAPAAAAAAAPPPTPAPPPP---------------PAPV 140
Q ++ A PPA PP+ P PP PPP P P
Sbjct: 447 QTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQ 506
Query: 141 AAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGP---R 197
+P AP+ A+ A APP+ G + +++ P+A P APPA PPA P R
Sbjct: 507 RLPSPTSAPQQPASQA-APPTQG------QGRQSRPVAG---GPGAPPAARPPASPSPQR 556
Query: 198 RAPPPAVAAREPPL---PPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPV 249
+A PP A R+ + PP APP QQ P +PP G R A PV
Sbjct: 557 QAGPPQ-ATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPV 610
Score = 60.5 bits (145), Expect = 4e-09
Identities = 63/245 (25%), Positives = 84/245 (34%), Gaps = 44/245 (17%)
Query: 94 RNAARVQPPRRGA--TPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRA 151
R R P RG+ P+P P G + A PP PPP P
Sbjct: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGP------------ 467
Query: 152 AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAG---PRRAPPPAVAARE 208
P PGP + GP Q+ PP + PPAG P+R P P A ++
Sbjct: 468 ------PQPGPGPQRQGPPLQQ----RPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ 517
Query: 209 PPLPPPPQPPAPPQQQQP------PPPQPQPPPEGGAVRAGG---AARPVSLREVVRYLG 259
P P +Q +P PP +PP R G A R S+
Sbjct: 518 PASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKA 577
Query: 260 GSGGAGGRLTRGRVQ-----GLLEEEAAARGRLERTRLGALALPRGDRP---GRAPPAAS 311
GG+ +G Q +A+ G + RT PR P GR P +
Sbjct: 578 SGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLA 637
Query: 312 ARPSR 316
+PS+
Sbjct: 638 QKPSQ 642
Score = 50.8 bits (120), Expect = 3e-06
Identities = 42/129 (32%), Positives = 49/129 (37%), Gaps = 9/129 (6%)
Query: 94 RNAARVQPPRR-GATPPAPPRAPRGAPAAAAAAAPP---PTPAPPPPPAPVAAAAPARAP 149
R A Q R+ + PAPP+A P PP P PA P A A P P
Sbjct: 556 RQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGP 615
Query: 150 RAAAAAATAPPSPGPA-QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAARE 208
P PGPA +P P+ + PPPA AA A PP A
Sbjct: 616 --PTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAA--AGGPPHPQLNKSQSLTNAFN 671
Query: 209 PPLPPPPQP 217
P P PP+P
Sbjct: 672 LPEPAPPRP 680
Score = 50.1 bits (118), Expect = 5e-06
Identities = 75/291 (25%), Positives = 100/291 (34%), Gaps = 71/291 (24%)
Query: 165 AQPGPRAQRAAP---LAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPP 221
A P R + A+P P+P A P + + A PPA R PP PPQP P
Sbjct: 417 ALPRQRQRDASPGRGSHGQTPSPGALP-LGRQTSQQPAGPPA-QQRPPPQGGPPQP-GPG 473
Query: 222 QQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQG--LLEE 279
Q+Q PP Q +PPP+G ++L G G G R+ +
Sbjct: 474 PQRQGPPLQQRPPPQG-----------------QQHLSGLGPPAGSPLPQRLPSPTSAPQ 516
Query: 280 EAAARGRLERTRLGALALPRGDRPGRAPPAA--SARPSRSKRGGEERVLEKEEEEDDDED 337
+ A++ G + P PG APPAA A PS ++ G +
Sbjct: 517 QPASQAAPPTQGQGRQSRPVAGGPG-APPAARPPASPSPQRQAGPPQA------------ 563
Query: 338 EDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAP 397
+ VS + S P G Q Q GP Q + P P
Sbjct: 564 -TRQTSVSGPAPPKASGAPPGGQQRQ--------------------GPPQ-----KPPGP 597
Query: 398 GSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPAL---PGADGTP 445
TRQ + + G + P P P P KP L P D P
Sbjct: 598 AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP--KPQLAQKPSQDVPP 646
Score = 34.3 bits (77), Expect = 0.30
Identities = 33/107 (30%), Positives = 39/107 (36%), Gaps = 22/107 (20%)
Query: 182 PAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGG--- 238
P P PP A G P A A R + P P A P P GG
Sbjct: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA-----------PSPGSSGGGGF 76
Query: 239 ------AVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEE 279
AV+ AA + E V GGSGGAG RV +++E
Sbjct: 77 FSSLSNAVKQTTAAAAATFSEQVG--GGSGGAGRGGAASRVLLVIDE 121
Score = 33.9 bits (76), Expect = 0.39
Identities = 15/41 (36%), Positives = 18/41 (43%)
Query: 129 PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGP 169
P P PPPP A A P A ++ P+ PA P P
Sbjct: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
Score = 31.2 bits (69), Expect = 2.5
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 5/47 (10%)
Query: 127 PPPTPAPPPPPAPVAAAAPA-----RAPRAAAAAATAPPSPGPAQPG 168
P P P PP +P A P R+ A AA+ A PSPG + G
Sbjct: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGG 74
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 82.4 bits (202), Expect = 9e-16
Identities = 61/194 (31%), Positives = 81/194 (41%), Gaps = 14/194 (7%)
Query: 63 GPEPERTRAELEKLIQQRAVLRVSYKGS-----ISYRNAARVQPPRRGATPPAPPRAPRG 117
GP P+R L++ + +S G + R + P++ A+ APP +G
Sbjct: 471 GPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQG 530
Query: 118 APAAAAAAAP--PPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAA 175
+ A P PP PP P+P A P +A R + + APP A PG + ++
Sbjct: 531 RQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP 590
Query: 176 PLAAPPPAPAAPPAVAPPAGP-RRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPP 234
P PP PA P A AGP R PP P P P P P Q+ P Q PP
Sbjct: 591 P--QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQK--PSQDVPP 646
Query: 235 PEGGAVRAGGAARP 248
P A AGG P
Sbjct: 647 PATAA--AGGPPHP 658
Score = 65.5 bits (158), Expect = 1e-10
Identities = 56/175 (32%), Positives = 72/175 (41%), Gaps = 36/175 (20%)
Query: 100 QPPRRGATPPA----PPRAPRGAPAAAAAAAPPPTPAPPPP---------------PAPV 140
Q ++ A PPA PP+ P PP PPP P P
Sbjct: 447 QTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQ 506
Query: 141 AAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGP---R 197
+P AP+ A+ A APP+ G + +++ P+A P APPA PPA P R
Sbjct: 507 RLPSPTSAPQQPASQA-APPTQG------QGRQSRPVAG---GPGAPPAARPPASPSPQR 556
Query: 198 RAPPPAVAAREPPL---PPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPV 249
+A PP A R+ + PP APP QQ P +PP G R A PV
Sbjct: 557 QAGPPQ-ATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPV 610
Score = 60.5 bits (145), Expect = 4e-09
Identities = 63/245 (25%), Positives = 84/245 (34%), Gaps = 44/245 (17%)
Query: 94 RNAARVQPPRRGA--TPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRA 151
R R P RG+ P+P P G + A PP PPP P
Sbjct: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGP------------ 467
Query: 152 AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAG---PRRAPPPAVAARE 208
P PGP + GP Q+ PP + PPAG P+R P P A ++
Sbjct: 468 ------PQPGPGPQRQGPPLQQ----RPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ 517
Query: 209 PPLPPPPQPPAPPQQQQP------PPPQPQPPPEGGAVRAGG---AARPVSLREVVRYLG 259
P P +Q +P PP +PP R G A R S+
Sbjct: 518 PASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKA 577
Query: 260 GSGGAGGRLTRGRVQ-----GLLEEEAAARGRLERTRLGALALPRGDRP---GRAPPAAS 311
GG+ +G Q +A+ G + RT PR P GR P +
Sbjct: 578 SGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLA 637
Query: 312 ARPSR 316
+PS+
Sbjct: 638 QKPSQ 642
Score = 50.4 bits (119), Expect = 4e-06
Identities = 80/308 (25%), Positives = 106/308 (34%), Gaps = 76/308 (24%)
Query: 165 AQPGPRAQRAAP---LAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPP 221
A P R + A+P P+P A P + + A PPA R PP PPQP P
Sbjct: 417 ALPRQRQRDASPGRGSHGQTPSPGALP-LGRQTSQQPAGPPA-QQRPPPQGGPPQP-GPG 473
Query: 222 QQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQG--LLEE 279
Q+Q PP Q +PPP+G ++L G G G R+ +
Sbjct: 474 PQRQGPPLQQRPPPQG-----------------QQHLSGLGPPAGSPLPQRLPSPTSAPQ 516
Query: 280 EAAARGRLERTRLGALALPRGDRPGRAPPAA--SARPSRSKRGGEERVLEKEEEEDDDED 337
+ A++ G + P PG APPAA A PS ++ G +
Sbjct: 517 QPASQAAPPTQGQGRQSRPVAGGPG-APPAARPPASPSPQRQAGPPQA------------ 563
Query: 338 EDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAP 397
+ VS + S P G Q Q GP Q + P P
Sbjct: 564 -TRQTSVSGPAPPKASGAPPGGQQRQ--------------------GPPQ-----KPPGP 597
Query: 398 GSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPAL---PGADGTP-----FGCP 449
TRQ + + G + P P P P KP L P D P G P
Sbjct: 598 AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP--KPQLAQKPSQDVPPPATAAAGGP 655
Query: 450 PGRKEKPS 457
P + K S
Sbjct: 656 PHPQLKAS 663
Score = 34.3 bits (77), Expect = 0.30
Identities = 33/107 (30%), Positives = 39/107 (36%), Gaps = 22/107 (20%)
Query: 182 PAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGG--- 238
P P PP A G P A A R + P P A P P GG
Sbjct: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA-----------PSPGSSGGGGF 76
Query: 239 ------AVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEE 279
AV+ AA + E V GGSGGAG RV +++E
Sbjct: 77 FSSLSNAVKQTTAAAAATFSEQVG--GGSGGAGRGGAASRVLLVIDE 121
Score = 33.9 bits (76), Expect = 0.39
Identities = 15/41 (36%), Positives = 18/41 (43%)
Query: 129 PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGP 169
P P PPPP A A P A ++ P+ PA P P
Sbjct: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
Score = 31.2 bits (69), Expect = 2.5
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 5/47 (10%)
Query: 127 PPPTPAPPPPPAPVAAAAPA-----RAPRAAAAAATAPPSPGPAQPG 168
P P P PP +P A P R+ A AA+ A PSPG + G
Sbjct: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGG 74
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 81.6 bits (200), Expect = 2e-15
Identities = 71/227 (31%), Positives = 83/227 (36%), Gaps = 68/227 (29%)
Query: 102 PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAP--VAAAAPARAPRAAAAAATAP 159
PR G T A A P A PPPTP PPPPP P + +++P + P +P
Sbjct: 150 PRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTP------LVSP 203
Query: 160 PSPGPAQPGPRAQRAAPLAAPPPAPAAPP--------------AVAPPAGPRRAPP---- 201
P P P P A PPP P PP AV P P PP
Sbjct: 204 PGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPP 263
Query: 202 ------------------PAVAAREPPLPPPPQP-----------PAPP-----QQQQPP 227
PA A+EPP PPPP P PAPP + P
Sbjct: 264 LPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETP 323
Query: 228 PPQP------QPPPEGGAVRAGGA--ARPVSLREVVRYLGGSGGAGG 266
PP P Q PP+ +A A A P S + + G GAGG
Sbjct: 324 PPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGG 370
Score = 72.4 bits (176), Expect = 1e-12
Identities = 74/263 (28%), Positives = 94/263 (35%), Gaps = 45/263 (17%)
Query: 4 PPAL---PPPETAAAATTAAAASSSAASPHYQEWIL-DTIDSLRSRKARPDLERICRMVR 59
PP L PPP +A + +S A P + +L D R RK +R +
Sbjct: 15 PPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIE 74
Query: 60 RRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRG--------ATPPAP 111
G E GS + R A+ PP G PA
Sbjct: 75 SSKGTNKEGG-------------------GSANTRGAST--PPTLGDLFAGGFPVLRPAG 113
Query: 112 PRAPRGAPAAAAAAAPPPTPAPPP-----PPAPVAAAAPARAPRAAAAAATAPPSPG-PA 165
R G + P+P P P P A+ A AA TAPP P PA
Sbjct: 114 QRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPA 173
Query: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQ 225
P P P PPP P P+ +P P +PP + P+ PP P APP
Sbjct: 174 PPPP-----TPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPP 228
Query: 226 PPPPQPQPPPEGGAVRAGGAARP 248
PPPP P P P +V + A +P
Sbjct: 229 PPPPTPPPLPP-ASVLSDKAVKP 250
Score = 71.6 bits (174), Expect = 2e-12
Identities = 60/196 (30%), Positives = 70/196 (35%), Gaps = 61/196 (31%)
Query: 96 AARVQPPRRGAT-----------PPAPPRAPRGAPAAAAAAAPP---------------- 128
AAR PPR PP PP P +P +PP
Sbjct: 161 AARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVP 220
Query: 129 --PTPAPP-----PPPAPVAAAAPARAPRAAAAAATAPPSPGP-------AQPGPRAQRA 174
P P PP PPP P A+ +A + A PP P P PG +A+ A
Sbjct: 221 CAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPA 280
Query: 175 APLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLP--------PPPQPPAPPQQQQP 226
+P A P APP PP P + P + PPLP PPP PP P Q P
Sbjct: 281 SP-AQDAQEPPAPP---PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336
Query: 227 P--------PPQPQPP 234
P P P PP
Sbjct: 337 PQKAGAQALPAPPAPP 352
Score = 61.2 bits (147), Expect = 2e-09
Identities = 53/178 (29%), Positives = 64/178 (35%), Gaps = 40/178 (22%)
Query: 107 TPPAP---PRAPRGAPAAAAAAAPPPTPAPP-PPPAPVAAAAPARAPRAAAAAATAPPSP 162
+PP P P AP A PPP P PP PPP P A+ +A + A PP P
Sbjct: 202 SPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIP 261
Query: 163 GP-------AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAG-------------------- 195
P PG +A+ A+P PA PP + P A
Sbjct: 262 PPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSE 321
Query: 196 -PRRAPPPAVAAREPP----LPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARP 248
P PP + + + PP P PPAPP Q P Q G GG P
Sbjct: 322 TPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQ----PFLQKKRHGRPGAGGGKLNP 375
Score = 59.7 bits (143), Expect = 7e-09
Identities = 47/161 (29%), Positives = 58/161 (36%), Gaps = 26/161 (16%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAP-------PPTPAPPPPPAPVAAAAPARAPRAAA 153
PP PP PP P + + A P PP P P P P P + A
Sbjct: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA 283
Query: 154 AAATAPPSPGPAQP-----GPRAQ-RAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAR 207
A PP+P P P PRA A PL + PP + P + +APP A+
Sbjct: 284 QDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343
Query: 208 EPPLPPPP-------------QPPAPPQQQQPPPPQPQPPP 235
P PP P +P A + PPP P P
Sbjct: 344 ALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
Score = 50.8 bits (120), Expect = 3e-06
Identities = 53/196 (27%), Positives = 60/196 (30%), Gaps = 68/196 (34%)
Query: 99 VQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPA------------ 146
V PP PP PP P GAP PPP P+ PP ++ A
Sbjct: 3 VPPPPPPPLPPPPP--PLGAP-------PPPPPSAPPVSTDTSSLRRADPKGRSALLADI 53
Query: 147 ---------------RAPR--------------AAAAAATAPPSPGPAQPG------PRA 171
AP+ A A+ PP+ G G P
Sbjct: 54 QQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAG 113
Query: 172 QR--AAPLAAPPPAPAAPP----------AVAPPAGPRRAPPPAVAAREPPLPPPPQPPA 219
QR A P AP + PPA PR PP P PA
Sbjct: 114 QRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPA 173
Query: 220 PPQQQQPPPPQPQPPP 235
PP PPPP P PPP
Sbjct: 174 PPPPTPPPPPPPLPPP 189
Score = 47.8 bits (112), Expect = 3e-05
Identities = 47/159 (29%), Positives = 59/159 (37%), Gaps = 35/159 (22%)
Query: 96 AARVQPPRRGATPPAPP-----------RAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAA 144
A P + PPAPP RA AP + TP P PP +P A
Sbjct: 277 AEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336
Query: 145 PARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAV 204
P +A A A APP+P +QP + +R A G + PPPA
Sbjct: 337 P---QKAGAQALPAPPAPPGSQPFLQKKRHGRPGA--------------GGGKLNPPPAP 379
Query: 205 AAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAG 243
AR P + + QQ P QP GG +R G
Sbjct: 380 PARS----PTTELSSKSQQATAWTPTQQP---GGQLRNG 411
Score = 39.7 bits (91), Expect = 0.007
Identities = 16/26 (61%), Positives = 17/26 (65%), Gaps = 4/26 (15%)
Query: 210 PLPPPPQPPAPPQQQQPPPPQPQPPP 235
P+PPPP PP PP PPPP PPP
Sbjct: 2 PVPPPPPPPLPP----PPPPLGAPPP 23
Score = 33.5 bits (75), Expect = 0.50
Identities = 21/75 (28%), Positives = 29/75 (38%), Gaps = 12/75 (16%)
Query: 182 PAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVR 241
P P PP PP PPP + A PPP PP+ P + P+G +
Sbjct: 2 PVPPPPPPPLPP------PPPPLGA------PPPPPPSAPPVSTDTSSLRRADPKGRSAL 49
Query: 242 AGGAARPVSLREVVR 256
+ LR+V +
Sbjct: 50 LADIQQGTRLRKVTQ 64
Score = 30.0 bits (66), Expect = 5.6
Identities = 13/28 (46%), Positives = 15/28 (53%), Gaps = 2/28 (7%)
Query: 176 PLAAPPPAPAAPPAVAPPAGPRRAPPPA 203
P+ PPP P PP PP G PPP+
Sbjct: 2 PVPPPPPPPLPPPP--PPLGAPPPPPPS 27
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 81.6 bits (200), Expect = 2e-15
Identities = 57/165 (34%), Positives = 64/165 (38%), Gaps = 37/165 (22%)
Query: 90 SISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPP--------------------- 128
SIS +A PP G + P P APAAA PP
Sbjct: 1397 SISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEK 1456
Query: 129 PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPP 188
P P PPP P P P PP P PA P P A ++PPP P PP
Sbjct: 1457 PPPTPPPAPTPQPQPPP------------PPPPPQPALPSPPPLVAPTPSSPPPPPLPPP 1504
Query: 189 AVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQP 233
PPA P PPP AA PL PP+ PA P + P P +P
Sbjct: 1505 --PPPAMPSPPPPPPPAA--APLAAPPEEPAAPSPEDPELPDTRP 1545
Score = 77.4 bits (189), Expect = 3e-14
Identities = 66/217 (30%), Positives = 84/217 (38%), Gaps = 54/217 (24%)
Query: 74 EKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPP---- 129
E + + L+ S +IS + + P+ +TP PP AP AAA PPP
Sbjct: 1385 EDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAP-----AAAVPGPPPLPGL 1439
Query: 130 -------TPAPP-----PPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPL 177
TP PP PPP P A P P PP P PA P P PL
Sbjct: 1440 PSANSNGTPEPPLLEEKPPPTPPPAPTPQPQP------PPPPPPPQPALPSP-----PPL 1488
Query: 178 AAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPP--------APPQQQQPPPP 229
AP P+ PP + PP PPPA +P PP PP APP++ P P
Sbjct: 1489 VAPTPSSPPPPPLPPP------PPPA-------MPSPPPPPPPAAAPLAAPPEEPAAPSP 1535
Query: 230 QPQPPPEGGAVRAGGAARPVSL-REVVRYLGGSGGAG 265
+ P+ + ++ E G SGG G
Sbjct: 1536 EDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEG 1572
Score = 71.2 bits (173), Expect = 2e-12
Identities = 64/246 (26%), Positives = 93/246 (37%), Gaps = 77/246 (31%)
Query: 67 ERTRAELEKLIQQRAVLRVSYKGS-ISYRNAARVQPP--RRGATPP-APPRA-PRGAPAA 121
E+ A+++++ +++ ++ + S + + + + PP + G TPP +PP++ P PA
Sbjct: 1261 EKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPAR 1320
Query: 122 AAAAAPPPTPAPPPPPAP----------------VAAAAPARAPR--------------- 150
PP TPA P PP + P+ R
Sbjct: 1321 GLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSF 1380
Query: 151 -------------------AAAAAATAPPSPGP----AQPGPRAQRAAPLAAPPPAPAAP 187
+A +A PP GP GP AA + PPP P P
Sbjct: 1381 SSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLP 1440
Query: 188 PAVA-----PPAGPRRAPP-----PAVAAREPPLPPPPQP--PAPP------QQQQPPPP 229
A + PP + PP P + PP PPPPQP P+PP PPPP
Sbjct: 1441 SANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPP 1500
Query: 230 QPQPPP 235
P PPP
Sbjct: 1501 LPPPPP 1506
Score = 57.0 bits (136), Expect = 4e-08
Identities = 94/363 (25%), Positives = 118/363 (32%), Gaps = 74/363 (20%)
Query: 101 PPRRGATPP--APPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATA 158
P R G TP A GA A A +P PPPP A + P A
Sbjct: 732 PERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPP----TAQSTQPTPHGLLLEAGG 787
Query: 159 PPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAV---APPAGPRRA--------PPPAVAAR 207
P PL PPP P P+V AP P + P A
Sbjct: 788 PD--------------LPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAP 833
Query: 208 EPPLPPPPQPPAPPQQ---------QQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYL 258
+PP PPPP PP P Q +P P P+ PE G + E +
Sbjct: 834 QPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPA 893
Query: 259 GGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSK 318
G G G + G+ + A R P+G + R P S S
Sbjct: 894 PGDTGVGPPNSEGK-----DPAGAYRS----------PSPQGTKAPRFVPLTSICFPDSL 938
Query: 319 RGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVK 378
EER EE +D G E D AGA GP
Sbjct: 939 LQDEERSFFPTMEEMFGGGA-ADDYGKAGPPEDEGDPKAGA---------GPPPGP---P 985
Query: 379 EWTPCGPH-QGQDEGRGP-APGSG---TRQVFSMAAMNKEGGTASVATGPDSPSPVPLPP 433
+ P GP+ G+ G GP PG G + + +N E + +GP +P P PP
Sbjct: 986 AYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAE-PLGLIQSGPHQAAPPPPPP 1044
Query: 434 GKP 436
P
Sbjct: 1045 PPP 1047
Score = 50.8 bits (120), Expect = 3e-06
Identities = 64/231 (27%), Positives = 76/231 (32%), Gaps = 52/231 (22%)
Query: 119 PAAAAAAAPPP----TPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP-----GPAQPGP 169
PA A PP P PPPPP + A +AAAAA SP A PGP
Sbjct: 216 PAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP 275
Query: 170 RAQRAAPLAAPPPAPAAP-----------PAVAPPAGPRRAPPPAVAARE--------PP 210
PPP A P PA A P P PPPA A + P
Sbjct: 276 ----------PPPERALPRQDTVIKHYQRPASAQPPPP---PPPAHALQHYLSCGGSYPS 322
Query: 211 LPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTR 270
+ P P P P + G GA S R G GGAGG
Sbjct: 323 MGHRANLACSPLGGGEPSPGAGEPSKAG---PSGATAGASGRATGPEAAGGGGAGG--GG 377
Query: 271 GRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGG 321
G + +++ G+ G G PP ++A P GG
Sbjct: 378 GGYRPIIQSPGYKTGK------GGYGAAAGGATRPPPPRSTATPKCQSLGG 422
Score = 50.4 bits (119), Expect = 4e-06
Identities = 70/247 (28%), Positives = 91/247 (36%), Gaps = 66/247 (26%)
Query: 97 ARVQPPRRGATPPAPPRAPRGAP-----------AAAAAAAPPP--------TPAPPPPP 137
A+ P R G PP PP PR P AAAAA P P PPPP
Sbjct: 222 AQTPPYRPG--PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPE 279
Query: 138 APVAAAAPARAPRAAAAAATAPPSPGPAQP--------------GPRAQRA-APLAAPPP 182
+ A+A PP P PA G RA A +PL P
Sbjct: 280 RALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEP 339
Query: 183 AP-AAPPAVAPPAGPR-----RAPPPAVA----------AREPPLPPPPQP-------PA 219
+P A P+ A P+G RA P A P + P A
Sbjct: 340 SPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAA 399
Query: 220 PPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGR-LTRGRVQGLLE 278
+PPPP+ P+ ++ GG A + + G+GGAGG+ + G+ QGLL
Sbjct: 400 AGGATRPPPPRSTATPKCQSL--GGPAAAYATGKA----SGAGGAGGQAYSPGQPQGLLG 453
Query: 279 EEAAARG 285
+A +G
Sbjct: 454 PQAYGQG 460
Score = 50.4 bits (119), Expect = 4e-06
Identities = 49/196 (25%), Positives = 73/196 (37%), Gaps = 27/196 (13%)
Query: 136 PPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAG 195
PP PV + A+ P +A ++APP PA PPP P P
Sbjct: 1670 PPVPVRRSGQAKNP-VSAGGSSAPPPKAPA--------------PPPKPETPEKTTSEKP 1714
Query: 196 PRRAPPPAVAAREPPLPPPPQ--PPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLRE 253
P + P A+ EPP P P P ++++ + + P G +G RP
Sbjct: 1715 PEQTPETAMP--EPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRP----- 1767
Query: 254 VVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASA- 312
R L A RL + R + E + + G A G PG + + S+
Sbjct: 1768 -ERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSP 1826
Query: 313 -RPSRSKRGGEERVLE 327
PS +R R+L+
Sbjct: 1827 GAPSEDERAVPGRLLK 1842
Score = 50.1 bits (118), Expect = 5e-06
Identities = 65/269 (24%), Positives = 80/269 (29%), Gaps = 127/269 (47%)
Query: 108 PPAPPR--------APRGAPAAA-------------AAAAPPPTPAPPPPPAPV------ 140
PP PP+ AP +P+A+ A PPP P PPPPP P+
Sbjct: 795 PPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHL 854
Query: 141 -------AAAAPARAPRAA-----------AAAATAPPSPG------------------- 163
AA +P P + A PP+PG
Sbjct: 855 RSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYR 914
Query: 164 -PAQPGPRAQRAAPL-----------------------------------AAPPPAPAAP 187
P+ G +A R PL A PP P
Sbjct: 915 SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDP 974
Query: 188 PAVA-PPAGPRRAPP-----PAVAAREPPLPP--------PPQPPA-------------P 220
A A PP GP P P A+ P P PP+ P+ P
Sbjct: 975 KAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGP 1034
Query: 221 PQQQQPPPPQPQPPPEGGAVRAGGAARPV 249
Q PPPP P PPP + GG P+
Sbjct: 1035 HQAAPPPPPPPPPPPAPASEPKGGLTSPI 1063
Score = 47.4 bits (111), Expect = 3e-05
Identities = 60/231 (25%), Positives = 75/231 (32%), Gaps = 46/231 (19%)
Query: 95 NAARVQPPRRGATPPAPPRAPRGAPAAAAA--------AAPPPTPAPPPPPAPVAAAAPA 146
+ A + P G P PP P A AAPPP P PPPPPAP A+ P
Sbjct: 999 SGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAP--ASEPK 1056
Query: 147 RAPRAAAAAATAPPS------------PGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPA 194
+ +T P P P+ A A
Sbjct: 1057 GGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRL 1116
Query: 195 GPRRAPPPAVAAREPP----------LPPPPQPPAPPQQQQPP-------PPQPQPPPEG 237
PRR P + R P PP P P P ++ + P PP+P+ P
Sbjct: 1117 NPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRI 1176
Query: 238 GAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLE 288
+ A P S + GA RGR +G EEA RLE
Sbjct: 1177 RPLEVPTTAGPASAST------PTDGAKKPRGRGRGRGRKAEEAGGT-RLE 1220
Score = 45.4 bits (106), Expect = 1e-04
Identities = 91/347 (26%), Positives = 120/347 (34%), Gaps = 61/347 (17%)
Query: 117 GAPAAAAAAAPPPTPAPPPPP------APVAAAAPARAPRAAAAAATAPPSPGPAQP--G 168
G AAA A PP P P P AA A +A A A A SPG Q G
Sbjct: 395 GYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQA-YSPGQPQGLLG 453
Query: 169 PRAQ-------RAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPP 221
P+A +A L+ P PP PP+GP PPP +A + P Q
Sbjct: 454 PQAYGQGFGGGQAQDLSKAPSYSGGPP--QPPSGP---PPPGLATCQSYSPDQLQGQLYG 508
Query: 222 QQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGG-----SGGAGGRLTRGRVQGL 276
Q + P P P +G + + + GG S G GG + +
Sbjct: 509 VQGE-PYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRP 567
Query: 277 LEEEAAARGRLERTRLGA----LALPRGDRPGRAPP-----AASARPSRSKRGGEERVLE 327
L+ A GA L+ P APP AA A + K G E +L
Sbjct: 568 LQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSE-LLA 626
Query: 328 KEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQ 387
+ EDEE + + P R +GA L GE G A + +
Sbjct: 627 GPGGPPAERTEDEEFLIQHLLQAPSPPRTSGAD--GLVGEDGAADASKGL---------- 674
Query: 388 GQDEGRGPAPGS------------GTRQVFSMAAMNKEGGTASVATG 422
G G G PG+ + V +A EG TA++ G
Sbjct: 675 GGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELG 721
Score = 43.1 bits (100), Expect = 6e-04
Identities = 72/288 (25%), Positives = 88/288 (30%), Gaps = 89/288 (30%)
Query: 184 PAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAG 243
P + PP P ++ PP+V AR PQPPA P PPP
Sbjct: 1297 PLYQAGLTPPLSPPKSVPPSVPARGLQ----PQPPATPAVPHPPP--------------- 1337
Query: 244 GAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRP 303
G+ G GG L +GL LG
Sbjct: 1338 ---------------SGAFGLGGALEAAESEGL--------------GLGC--------- 1359
Query: 304 GRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPES--------DR 355
PS KR EE L++ E DEED V++ ++ ES D
Sbjct: 1360 ----------PSPCKRLDEE--LKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDD 1407
Query: 356 PAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGG 415
P A + GP A P P G A +GT + K
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLP------GLPSANSNGTPE--PPLLEEKPPP 1459
Query: 416 TASVATGPDSPSPVPLPPGKPALPG----ADGTPFGCPPGRKEKPSDP 459
T A P P P PP +PALP TP PP P P
Sbjct: 1460 TPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPP 1507
Score = 42.0 bits (97), Expect = 0.001
Identities = 107/537 (19%), Positives = 146/537 (27%), Gaps = 126/537 (23%)
Query: 4 PPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHG 63
PP PPP A A+ +S + +L T R+ P + ++ + +
Sbjct: 1041 PPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYE 1100
Query: 64 PEPERTRAELEKLIQQRA------VLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRG 117
E + +A++ I+ V + ++S PP G P P R RG
Sbjct: 1101 FEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPG--PDGPRR--RG 1156
Query: 118 APAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP---------- 167
A PP P P P P A A+ + P+ G +P
Sbjct: 1157 RKPTKAKRDGPPRPRGRP------RIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRK 1210
Query: 168 -----GPRAQRAAPLAAPPPAPAAPPAVAPPAGP-------------------------- 196
G R + PL P A + +G
Sbjct: 1211 AEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEV 1270
Query: 197 ----------------------RRAPPPAVAAREPPLPPP----PQPPAPPQQQQPP--P 228
+R PP A PPL PP P PA Q QPP P
Sbjct: 1271 EEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATP 1330
Query: 229 PQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGL-LEEEAAARGRL 287
P PPP G G GG L +GL L + +
Sbjct: 1331 AVPHPPPSGAF-----------------------GLGGALEAAESEGLGLGCPSPCKRLD 1367
Query: 288 ERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEG 347
E + LP A + S + + D + ++
Sbjct: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPA 1427
Query: 348 SEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSM 407
+ VP G NG P +E+ P P P P
Sbjct: 1428 AAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALP---- 1483
Query: 408 AAMNKEGGTASVATGPDSPSPVPLP-------PGKPALPGADGTPFGCPPGRKEKPS 457
VA P SP P PLP P P P P PP PS
Sbjct: 1484 ------SPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPS 1534
Score = 41.2 bits (95), Expect = 0.002
Identities = 40/173 (23%), Positives = 66/173 (38%), Gaps = 15/173 (8%)
Query: 83 LRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAP---AAAAAAAPPPTPAPPPPPAP 139
L V + +++ ++ RV + PP P R A +A ++APPP P PPP P
Sbjct: 1645 LYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKA-PAPPPKP 1703
Query: 140 ------VAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPP 193
+ P + P A AP P +P + + + A
Sbjct: 1704 ETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERAT--- 1760
Query: 194 AGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQP--PPEGGAVRAGG 244
+G + P ++A +P P+ + +PPP + + GG AGG
Sbjct: 1761 SGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGG 1813
Score = 35.4 bits (80), Expect = 0.13
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 20/142 (14%)
Query: 113 RAPRGAPAAAAAAAPPPTPA-------PPPPPAPVAAAAPARA--PRAAAAAATAPPSPG 163
R P+ P+A++ + +P+ P P ++ A P + P ++A +A P+
Sbjct: 98 RGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASF 157
Query: 164 PAQPGPRAQRAAPLAAPPPAPAAPPAVAPP----AGPRRAP--PPAVA----AREPPLPP 213
++P P + L PP +P A ++P P +AP P ++ A L P
Sbjct: 158 GSRPFP-VPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGP 216
Query: 214 PPQPPAPPQQQQPPPPQPQPPP 235
PA +P PP P PPP
Sbjct: 217 AGLGPAQTPPYRPGPPDPPPPP 238
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 81.3 bits (199), Expect = 2e-15
Identities = 69/247 (27%), Positives = 93/247 (37%), Gaps = 33/247 (13%)
Query: 101 PPRRGATP--PAPPRAPRGAPA----AAAAAAPPPTPAPPPPPA-------PVAAAAPAR 147
PP+ G P P PP P+G P + + +PP P PPP P P
Sbjct: 61 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120
Query: 148 APRAAAAAATAPPSPGPAQ-PGPRAQRAAPLAAPPPAPAAPP--------AVAPPAGPRR 198
P PP PG Q P P+ ++ +PP P PP PP G +
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180
Query: 199 APPPAVAAREPPLPPPPQPPAPPQQ------QQPPPPQPQPPPEGGAVRAGGAARPVSLR 252
PPP + PPP +P PP Q Q PP +PQ PP G + G P
Sbjct: 181 GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP 240
Query: 253 EVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALP---RGDRPGRAPPA 309
+ GG+ G G+ QG + ++ + R+ G P G+ P PP
Sbjct: 241 QGPPPQGGNKPQGPP-PPGKPQG-PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 298
Query: 310 ASARPSR 316
A P +
Sbjct: 299 AGGNPQQ 305
Score = 80.1 bits (196), Expect = 5e-15
Identities = 49/139 (35%), Positives = 57/139 (41%), Gaps = 9/139 (6%)
Query: 108 PPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP 167
PP PP P+G P P P P P P +R+PR+ PP G QP
Sbjct: 50 PPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 108
Query: 168 -GPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP------PPQPPAP 220
GP P PP P PP P+ PP +R P PP PPQ
Sbjct: 109 QGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 168
Query: 221 PQQQQPPPPQP-QPPPEGG 238
PQ PPP +P PPP+GG
Sbjct: 169 PQGPPPPPGKPQGPPPQGG 187
Score = 72.4 bits (176), Expect = 1e-12
Identities = 54/171 (31%), Positives = 64/171 (37%), Gaps = 28/171 (16%)
Query: 101 PPRRGAT----PPAPPRAPRGAPAAAA----AAAPPPTPAPPPPPAPVAAAAPARAPRAA 152
PP +G PP PP P+G P PP P PPP +R+ ++
Sbjct: 161 PPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGD-----KSRSSQSP 215
Query: 153 AAAATAPPSPGPAQP-GPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPL 211
PP G QP GP P PP P PP P+ P + +
Sbjct: 216 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSAR 275
Query: 212 PPPPQPPAPPQQ-----QQPPPP------QPQPPPEG---GAVRAGGAARP 248
PP +P PPQQ Q PPPP QPQ PP G G R RP
Sbjct: 276 SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 326
Score = 72.0 bits (175), Expect = 1e-12
Identities = 82/332 (24%), Positives = 111/332 (33%), Gaps = 71/332 (21%)
Query: 127 PPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQ-PGPRAQRAAPLAAPPPAPA 185
PPP P P P P P PP PG Q P P+ ++ +PP P
Sbjct: 50 PPPPPGKPQGPPPQGGNKPQ-----------GPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 98
Query: 186 APP--------AVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQ------QQPPPPQP 231
PP PP G + PPP R PPP +P PP Q + PP +P
Sbjct: 99 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 158
Query: 232 Q-PPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERT 290
Q PPP+GG G P + G GG+ +G + +G R+
Sbjct: 159 QGPPPQGGNQPQGPPPPPGKPQ-------GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRS 211
Query: 291 RLGALALPRGDRP--GRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGS 348
P+G P G P P + + +G
Sbjct: 212 SQSPPGKPQGPPPQGGNQPQGPPPPPGK-----------------------PQGPPPQGG 248
Query: 349 EVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQ-DEGRGPAPGSGTRQVFSM 407
P+ P G + G +S R P GP Q + + +GP P +G
Sbjct: 249 NKPQGPPPPGKPQGP-PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG------ 301
Query: 408 AAMNKEGGTASVATGPDSPSPVPLPPGKPALP 439
N + A A P P P P G+P+ P
Sbjct: 302 ---NPQQPQAPPAGQPQGP-PRPPQGGRPSRP 329
Score = 70.5 bits (171), Expect = 4e-12
Identities = 80/324 (24%), Positives = 105/324 (32%), Gaps = 72/324 (22%)
Query: 137 PAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPA-PAAPPAVAPPAG 195
P+ +A +P+ PP PG Q P P PPP P PP +
Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88
Query: 196 PRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVV 255
R+PP P PPPQ PQ PPP +PQ PP G R G P
Sbjct: 89 SPRSPP------GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPP------- 135
Query: 256 RYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGD--RPGRAPPAASAR 313
G+ QG P+GD R R+PP
Sbjct: 136 ---------------GKPQG--------------------PPPQGDKSRSPRSPPGKPQG 160
Query: 314 PSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAG-AQHHQLNGERGPQS 372
P +GG + + + +G + P+ P G Q G++ S
Sbjct: 161 P--PPQGG------NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSS 212
Query: 373 AKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLP 432
K P P QG ++ +GP P G Q G P P P P
Sbjct: 213 QSPPGKPQGP--PPQGGNQPQGPPPPPGKPQ----------GPPPQGGNKPQGPPPPGKP 260
Query: 433 PGKPALPGADGTPFGCPPGRKEKP 456
G PA G+ PPG+ + P
Sbjct: 261 QGPPAQGGSKSQSARSPPGKPQGP 284
Score = 67.4 bits (163), Expect = 3e-11
Identities = 55/155 (35%), Positives = 66/155 (42%), Gaps = 31/155 (20%)
Query: 101 PPRRGATP--PAPPRAPRGAPA----AAAAAAPPPTPAPPPPPA-------PVAAAAPAR 147
PP+ G P P PP P+G P + ++ +PP P PPP P P
Sbjct: 183 PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 242
Query: 148 APRAAAAAATAPPSPG-----PAQPGPRAQRAAPLAAPPPAPAAPPAVAP--PAGPRRAP 200
P PP PG PAQ G ++Q A +PP P PP P GP P
Sbjct: 243 PPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSAR---SPPGKPQGPPQQEGNNPQGP---P 296
Query: 201 PPAVAAREPPLPPP---PQ-PPAPPQQQQPP-PPQ 230
PPA + P PP PQ PP PPQ +P PPQ
Sbjct: 297 PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 31.6 bits (70), Expect = 1.9
Identities = 35/132 (26%), Positives = 51/132 (38%), Gaps = 15/132 (11%)
Query: 335 DEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTPCGPHQGQD---- 390
+ED +E+ S + P+ P G N +GP + + P G ++ Q
Sbjct: 20 NEDVSQEESPSLIAGNPQGPSPQGG-----NKPQGPPPPPGKPQGPPPQGGNKPQGPPPP 74
Query: 391 -EGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGKPALPGADG--TPFG 447
+ +GP P G + + K G G + P P PPGKP P G P G
Sbjct: 75 GKPQGPPP-QGDKSRSPRSPPGKPQGPPP--QGGNQPQGPPPPPGKPQGPPPQGGNRPQG 131
Query: 448 CPPGRKEKPSDP 459
PP K + P
Sbjct: 132 PPPPGKPQGPPP 143
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 80.5 bits (197), Expect = 4e-15
Identities = 62/195 (31%), Positives = 82/195 (42%), Gaps = 18/195 (9%)
Query: 85 VSYKGSISYRNAARVQPPRRGATP-----PAPPRAPRGAPAAAAAAAPPPTPA--PPPPP 137
V+ + ++S R A+ P TP PAP AP APA A+AA T + PP P
Sbjct: 484 VTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPA 543
Query: 138 APVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPR 197
+P +P A P PA+P + + + PPAP PP P P+
Sbjct: 544 SPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQ 603
Query: 198 RAPPPAV-AAREPPLPPPPQPPAPPQ----QQQPPPPQPQPPPEGGAVRAGGAARPVSLR 252
P V ++ P PPP PP PPQ Q + P P P G A + PVSL
Sbjct: 604 ALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPA-----SPSPVSLS 658
Query: 253 EVVRY-LGGSGGAGG 266
+ LG + GG
Sbjct: 659 NPAQVDLGAATAEGG 673
Score = 59.7 bits (143), Expect = 7e-09
Identities = 46/141 (32%), Positives = 59/141 (41%), Gaps = 12/141 (8%)
Query: 96 AARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPR----A 151
AA V+ R PAP R P + + + PP APP PP + P PR +
Sbjct: 555 AAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPP--APPLPPGSGSPGTPQALPRRLVGS 612
Query: 152 AAAAATAPPS--PGPAQPGPRAQRAAPLAAPP--PAPAAPPAV--APPAGPRRAPPPAVA 205
+ A T PP P P QP R R +P + P P PA+P V + PA A
Sbjct: 613 SLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEG 672
Query: 206 AREPPLPPPPQPPAPPQQQQP 226
+ P PPA P Q +P
Sbjct: 673 GAPEAISGVPTPPAIPPQPRP 693
Score = 50.1 bits (118), Expect = 5e-06
Identities = 58/213 (27%), Positives = 83/213 (38%), Gaps = 31/213 (14%)
Query: 4 PPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLER-ICRMVRRRH 62
P P P A A A A +S+A + + S + ++ P+ + M RR
Sbjct: 507 PATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTK 566
Query: 63 GPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGA--TPPAPPRAPRGAPA 120
P P R ++ R+ A PP G+ TP A PR G+ +
Sbjct: 567 RPAPARPTMPPPQVSGSRS------------SPPAPPLPPGSGSPGTPQALPRRLVGS-S 613
Query: 121 AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRA---QRAAPL 177
A PPP P PP PAR + A+ +P SPGPA P P + L
Sbjct: 614 LRAPTVPPPL-PPTPP-------QPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDL 665
Query: 178 AAPPPAPAAPPAVA----PPAGPRRAPPPAVAA 206
A AP A++ PPA P + P ++A+
Sbjct: 666 GAATAEGGAPEAISGVPTPPAIPPQPRPRSLAS 698
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 79.3 bits (194), Expect = 8e-15
Identities = 67/226 (29%), Positives = 81/226 (35%), Gaps = 49/226 (21%)
Query: 131 PAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAV 190
P PPPPP R P + GP P P +A PPP P PP
Sbjct: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRS----GPLPPVPLG-----IAPPPPTPRGPPP- 361
Query: 191 APPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVS 250
P G PPP R PLPPPP P PPPP P PP +G P
Sbjct: 362 -PGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPP------SSGNGPAPPP 414
Query: 251 LREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAA 310
L + GG GGR G L ++ +L +T PG +A
Sbjct: 415 LPPALVPAGGLAPGGGR-------GALLDQIRQGIQLNKT------------PGAPESSA 455
Query: 311 SARPSRSKRG----------GEERVLEKEEEEDD---DEDEDEEDD 343
P +S G R + +E +D DEDED+E D
Sbjct: 456 LQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGDEDEDDEWD 501
Score = 70.5 bits (171), Expect = 4e-12
Identities = 67/243 (27%), Positives = 76/243 (31%), Gaps = 61/243 (25%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP 160
PP RG P G + P P PPPP P P R PP
Sbjct: 318 PPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRG---------GPP 368
Query: 161 SPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAP 220
P P P R+ PL PPP PP PPPP PP P
Sbjct: 369 PPPP----PATGRSGPLPPPPPGAGGPPMP---------------------PPPPPPPPP 403
Query: 221 PQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEE 280
P P P P PP V AGG L GG G L + R L +
Sbjct: 404 PSSGNGPAPPPLPP---ALVPAGG-------------LAPGGGRGALLDQIRQGIQLNKT 447
Query: 281 AAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDE 340
A AL P G RS+ + +E ED DEDE
Sbjct: 448 PGA------PESSALQPPPQSSEGLVGALMHVMQKRSR-----AIHSSDEGEDQAGDEDE 496
Query: 341 EDD 343
+D+
Sbjct: 497 DDE 499
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 79.0 bits (193), Expect = 1e-14
Identities = 55/139 (39%), Positives = 57/139 (41%), Gaps = 31/139 (22%)
Query: 105 GATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPA----PVAAAAPARAPRAAAAAATAPP 160
G TPP PP P G PP P PPPP P A P R R PP
Sbjct: 233 GQTPPRPPLGPPG----------PPGPPGPPPPGQVLPPPLAGPPNRGDR------PPPP 276
Query: 161 SPGPAQPGPRAQRAAPLAAPPPAPAAP-PAVAPPAGPRRAPPPAVAAREPPLPPPPQPP- 218
P QP + PL PP P P P PP GP PPP PP P PP+PP
Sbjct: 277 VLFPGQPFGQ----PPLGPLPPGPPPPVPGYGPPPGP---PPPQQGPPPPPGPFPPRPPG 329
Query: 219 --APPQQQQPPPPQPQPPP 235
PP PPP P PPP
Sbjct: 330 PLGPPLTLAPPPHLPGPPP 348
Score = 77.0 bits (188), Expect = 4e-14
Identities = 68/193 (35%), Positives = 77/193 (39%), Gaps = 23/193 (11%)
Query: 59 RRRHGPEPERTRAELEKLIQ-QRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRG 117
R HG P T + L Q + + + G +S A P G++ A P+ RG
Sbjct: 147 RELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGKAG---PPGGSSRAAFPQGGRG 203
Query: 118 A---PAAAAAAAPPPTPAPP--PPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQ 172
P A P PA P PPP A P R P P PGP P P Q
Sbjct: 204 RGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGP------PGPPGPPGPPPPGQ 257
Query: 173 RAAPLAAPPP--APAAPPAVAPPAGPRRAPP--PAVAAREPPLP---PPPQPPAPPQQQQ 225
P A PP PP V P P PP P PP+P PPP PP PPQQ
Sbjct: 258 VLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPP-PPQQGP 316
Query: 226 PPPPQPQPPPEGG 238
PPPP P PP G
Sbjct: 317 PPPPGPFPPRPPG 329
Score = 73.2 bits (178), Expect = 6e-13
Identities = 52/143 (36%), Positives = 55/143 (38%), Gaps = 27/143 (18%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP 160
PP RG PP P P G P PP P PP PP PV P PP
Sbjct: 266 PPNRGDRPPPPVLFP-GQPFGQ----PPLGPLPPGPPPPVPGYGP-------------PP 307
Query: 161 SPGPAQPGPRAQRAAPLAAPPPAPAAPP-AVAP----PAGPRRAPPPAVAAREPPLPPPP 215
P P Q GP P PP P PP +AP P P APPPA PPP
Sbjct: 308 GPPPPQQGPPPP-PGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPT 366
Query: 216 QPPAPPQQQQPPPPQP---QPPP 235
P + PPP +PPP
Sbjct: 367 NSGMPTSDSRGPPPTDPYGRPPP 389
Score = 70.9 bits (172), Expect = 3e-12
Identities = 51/145 (35%), Positives = 52/145 (35%), Gaps = 18/145 (12%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPP-----PPPAPVAAAAPARAPRAAAAA 155
PPR PP PP P P PPP PP PPP + P P
Sbjct: 236 PPRPPLGPPGPPGPP--GPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQP----PL 289
Query: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPP--APAAPPAVAPPAGPRRAPPPAVAAREPPLPP 213
PP P P PG P PPP P PP PP P PP A P LP
Sbjct: 290 GPLPPGPPPPVPG----YGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345
Query: 214 PPQPPAPPQQQQPPPPQPQPPPEGG 238
PP P APP P PP G
Sbjct: 346 PP-PGAPPPAPHVNPAFFPPPTNSG 369
Score = 52.8 bits (125), Expect = 8e-07
Identities = 28/58 (48%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 193 PAGPRRAPPPAVAAREPPLPP--PPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARP 248
PAGP PPP A + PP PP PP PP PP PPP Q PPP G G P
Sbjct: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGP--PPPGQVLPPPLAGPPNRGDRPPP 275
Score = 32.3 bits (72), Expect = 1.1
Identities = 31/109 (28%), Positives = 37/109 (33%), Gaps = 15/109 (13%)
Query: 360 QHHQLNGE--RGPQSAKERVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTA 417
Q Q++GE GP R P G+ GR P G + A G
Sbjct: 176 QSGQMSGEGKAGPPGGSSRA-----AFPQGGRGRGRFPGAVPGGDRFPGPAGPG--GPPP 228
Query: 418 SVATGPDSPSPVPLPPGKPALPGADGT------PFGCPPGRKEKPSDPV 460
G P P PPG P PG P PP R ++P PV
Sbjct: 229 PFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPV 277
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 79.0 bits (193), Expect = 1e-14
Identities = 51/136 (37%), Positives = 53/136 (38%), Gaps = 5/136 (3%)
Query: 101 PPRRGATPPAPPRAPRGAPAAAAAAAP-PPTPAP--PPPPAPVAAAAPARAPRAAAAAAT 157
PP + PP P P G P A P PPT P PPP AP P
Sbjct: 398 PPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRL 457
Query: 158 APPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQP 217
PP P P +P P P P P PP PP P PPP PPL PP
Sbjct: 458 LPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPL-VPPLG 516
Query: 218 PAPPQQQQPPPPQPQP 233
PAPP PP P P P
Sbjct: 517 PAPP-GLFPPAPLPNP 531
Score = 70.9 bits (172), Expect = 3e-12
Identities = 74/268 (27%), Positives = 98/268 (36%), Gaps = 30/268 (11%)
Query: 65 EPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAA 124
E + +E EK Q++ S+ S ++ + PP+ + PP+ +AP
Sbjct: 358 EDDSDDSEAEKQSQKQHK-EESHSDGTSTASSQQQAPPQ--SVPPSQIQAP-------PM 407
Query: 125 AAPPPTPAPPPP---PAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPR-AQRAAPLAAP 180
PPP PP P P P P A P PG P PR P P
Sbjct: 408 PGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRP 467
Query: 181 PPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPP------APPQQQQPP---PPQP 231
P P PP PP P R PPP + PP PPP+P PP PP PP P
Sbjct: 468 PGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAP 527
Query: 232 QPPPEGGAVRAGGAARP----VSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRL 287
P P + RP S + + + A ++T + + + R+
Sbjct: 528 LPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAE--ITRFVPTALRV 585
Query: 288 ERTRLGALALP-RGDRPGRAPPAASARP 314
R GA A P R A P A A P
Sbjct: 586 RRENKGATAAPQRKSEDDSAVPLAKAAP 613
Score = 44.3 bits (103), Expect = 3e-04
Identities = 72/304 (23%), Positives = 104/304 (34%), Gaps = 72/304 (23%)
Query: 210 PLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRA-GGAARPVSLREVVRYLGGSGGAGGRL 268
PLP P P+ Q P P QPP A G R VS+ ++ + G GR
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGH-GVPRLPPGRK 198
Query: 269 TRGRVQGLLEEEAAARGRLERTRLG-ALALPRGDRPGRAPPAASARPSRSKRGGEERVLE 327
G G + ++ ++G AL LP P R P ++RG ++ V
Sbjct: 199 PPGPPPGPPPPQVV---QMYGRKVGFALDLP----PRRRDEDMLYSPELAQRGHDDDVSS 251
Query: 328 KEEEED--DDEDEDEEDDVSEGSEVPESDRPAGAQH--HQLNGERG-------------- 369
E++ +D D+D+ DD ++ S+ +SD + H+ NGER
Sbjct: 252 TSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFA 311
Query: 370 -----PQSAKERVKEWTPC-----------------------------------GPHQGQ 389
+ K+ +KE TP Q Q
Sbjct: 312 DMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQ 371
Query: 390 DEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPL--PPGKPALPGADGTPFG 447
+ + + GT S + S P P P PL PP P P G P G
Sbjct: 372 KQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP--PGPPTG 429
Query: 448 CPPG 451
PPG
Sbjct: 430 LPPG 433
Score = 40.0 bits (92), Expect = 0.005
Identities = 94/444 (21%), Positives = 149/444 (33%), Gaps = 54/444 (12%)
Query: 28 SPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPERTRAELEKLIQQRAVLRVSY 87
+P Q + + + + +K R ERI R+ + + P+ + +LE +Q+ Y
Sbjct: 66 NPVQQPQLNEKVLKDKRKKLRETFERILRLYEKEN-PDIYKELRKLEVEYEQKRAQLSQY 124
Query: 88 KGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR 147
++ +NA V+ P P AP P P PP
Sbjct: 125 FDAV--KNAQHVEV--ESIPLPDMPHAPSNI-----LIQDIPLPGAQPPSI--------- 166
Query: 148 APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAR 207
+A PP+ RA PL P PP PP P PPP V
Sbjct: 167 ---LKKTSAYGPPT--------RAVSILPLLGHG-VPRLPPGRKPPGPPPGPPPPQVVQM 214
Query: 208 EPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVV---RYLGGSGGA 264
P ++ + P+ G + E + ++ + +
Sbjct: 215 YGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDS 274
Query: 265 GGRLTRGRVQG--LLEEEAAARGRLERTRLGALALPRGDRPGRA-------PPAASARPS 315
+ G G + + R E + G L++ D PG++ +
Sbjct: 275 DTDKSDGESDGDEFVHRDNGERDNNEEKKSG-LSVRFADMPGKSRKKKKNMKELTPLQAM 333
Query: 316 RSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKE 375
+ G+E E E E+ ED+DE+D S+ SE + + + +G S ++
Sbjct: 334 MLRMAGQEIPEEGREVEEFSEDDDEDD--SDDSEAEKQSQKQHKEESHSDGTSTASSQQQ 391
Query: 376 RVKEWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPL-PPG 434
+ P P Q Q P PG + G + GP +P L PPG
Sbjct: 392 APPQSVP--PSQIQ---APPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPG 446
Query: 435 KPALPG--ADGTPFGCPPGRKEKP 456
P L G P G PPGR P
Sbjct: 447 MPGLRGPLPRLLPPGPPPGRPPGP 470
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,853,992
Number of Sequences: 37866
Number of extensions: 2873001
Number of successful extensions: 172379
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 3005
Number of HSP's successfully gapped in prelim test: 2477
Number of HSP's that attempted gapping in prelim test: 24334
Number of HSP's gapped (non-prelim): 52430
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.