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Search of human proteins with 38569505
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
(599 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 1178 0.0
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 963 0.0
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 217 2e-56
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 217 2e-56
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 213 5e-55
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 208 1e-53
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 207 2e-53
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 207 2e-53
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 206 5e-53
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 206 5e-53
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 206 6e-53
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 205 1e-52
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 201 2e-51
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 195 9e-50
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 185 9e-47
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 183 4e-46
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 183 4e-46
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 182 6e-46
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 182 6e-46
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 181 1e-45
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 179 5e-45
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 177 2e-44
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 175 9e-44
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 172 8e-43
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 172 1e-42
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 163 4e-40
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 163 4e-40
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 159 5e-39
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 157 3e-38
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi... 156 4e-38
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 1178 bits (3048), Expect = 0.0
Identities = 599/599 (100%), Positives = 599/599 (100%)
Query: 1 MDVHDLFRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLDFFGNKKSVPGVCG 60
MDVHDLFRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLDFFGNKKSVPGVCG
Sbjct: 1 MDVHDLFRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLDFFGNKKSVPGVCG 60
Query: 61 ASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKK 120
ASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKK
Sbjct: 61 ASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKK 120
Query: 121 VQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNI 180
VQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNI
Sbjct: 121 VQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNI 180
Query: 181 LDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALII 240
LDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALII
Sbjct: 181 LDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALII 240
Query: 241 SPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLL 300
SPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLL
Sbjct: 241 SPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLL 300
Query: 301 KQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDV 360
KQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDV
Sbjct: 301 KQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDV 360
Query: 361 EQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQ 420
EQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQ
Sbjct: 361 EQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQ 420
Query: 421 SIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKG 480
SIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKG
Sbjct: 421 SIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKG 480
Query: 481 VNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPE 540
VNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPE
Sbjct: 481 VNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPE 540
Query: 541 YIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQNSKKKVALEDKS 599
YIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQNSKKKVALEDKS
Sbjct: 541 YIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQNSKKKVALEDKS 599
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
Length = 491
Score = 963 bits (2490), Expect = 0.0
Identities = 491/491 (100%), Positives = 491/491 (100%)
Query: 109 MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ 168
MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ
Sbjct: 1 MSSVEAKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQ 60
Query: 169 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 228
EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK
Sbjct: 61 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 120
Query: 229 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI
Sbjct: 121 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 180
Query: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 348
LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR
Sbjct: 181 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 240
Query: 349 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 408
RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK
Sbjct: 241 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 300
Query: 409 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 468
KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC
Sbjct: 301 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 360
Query: 469 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 528
TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA
Sbjct: 361 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVA 420
Query: 529 NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN 588
NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN
Sbjct: 421 NVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFLEKAKDKQKKVTGQN 480
Query: 589 SKKKVALEDKS 599
SKKKVALEDKS
Sbjct: 481 SKKKVALEDKS 491
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 217 bits (553), Expect = 2e-56
Identities = 158/527 (29%), Positives = 268/527 (50%), Gaps = 26/527 (4%)
Query: 50 GNKK----SVPGVCGASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGAT 105
GN+K +V V T + + +KK+ L E ++ + + ++ + G
Sbjct: 252 GNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQ 311
Query: 106 IQWMSSVE----AKIEDKKVQRESKLTSGKLENLRKEKINFLRNKHK-IHVQGTDLPDPI 160
+ +E KIE + ++ + +L + +E++N R + + I V+G P PI
Sbjct: 312 TKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPI 371
Query: 161 ATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFS 220
++ Q I+ ++L ++ G++ PTPIQ QAIP ++ GR+L+ A TGSGKT+AF
Sbjct: 372 KSWVQCG----ISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFL 427
Query: 221 IP----ILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAK 276
+P I+ Q +G A+I++PTRELA QI +E K S+ G R+ ++ ++
Sbjct: 428 LPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISE 487
Query: 277 KFGPKSSKKFDILVTTPNRLIYLLKQDPPGI-DLASVEWLVVDESDKLFEDGKTGFRDQL 335
+ + + +I+V TP R+I +L + + +L V ++V+DE+D++F+ GF Q+
Sbjct: 488 QIA-ELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFD---MGFEPQV 543
Query: 336 ASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGS 395
I + + MFSATF +E + L I V +G R+ VEQ+++ +
Sbjct: 544 MRIVDNVRPDR-QTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEE 602
Query: 396 ETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTV 455
E L + L + V++FV E A L +L+ +H Q RD+ +
Sbjct: 603 EKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSII 662
Query: 456 HSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITF 515
+ F+ G +L+ T++ ARG+D K + LV+NY P +Y+HR GRTGRAGNKG A TF
Sbjct: 663 NDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTF 722
Query: 516 FTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLLSKQKK---KMIKK 559
TED + ++ +G VP ++ Q+K K+IKK
Sbjct: 723 ITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKK 769
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 217 bits (553), Expect = 2e-56
Identities = 157/473 (33%), Positives = 245/473 (51%), Gaps = 40/473 (8%)
Query: 134 NLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQM 193
NL++++I L+ + I VQG ++ PI F+ +N N+ +G+++PTPIQM
Sbjct: 176 NLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLN----HNLKKSGYEVPTPIQM 231
Query: 194 QAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRE 253
Q IPV L GR++LASA TGSGKT AF +P++M+ + K ALI++PTRELA QI R+
Sbjct: 232 QMIPVGLLGRDILASADTGSGKTAAFLLPVIMRALFES-KTPSALILTPTRELAIQIERQ 290
Query: 254 LIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVE 313
++ G ++ + + + +++ TP RL+ ++KQ ++L V+
Sbjct: 291 AKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQS--SVELCGVK 348
Query: 314 WLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVIS 373
+VVDE+D + K GF+ Q+ I L + + + SAT +EQ L N +
Sbjct: 349 IVVVDEADTML---KMGFQQQVLDI-LENIPNDCQTILVSATIPTSIEQLASQLLHNPVR 404
Query: 374 VSIGARNSAVETVEQELLFVGSETGKLLAMRELV--KKGFNPPVLVFVQSIERAKELFHE 431
+ G +N V Q +L+V + K + E++ KK F PPVLVFV + +L E
Sbjct: 405 IITGEKNLPCANVRQIILWV-EDPAKKKKLFEILNDKKLFKPPVLVFVDC-KLGADLLSE 462
Query: 432 LIYE--GINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF 489
+ + G+ IH+E++Q +R N + G V++ T +L RG+D V LV+N+D
Sbjct: 463 AVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDM 522
Query: 490 PTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLL 549
P+S EY+H+IGR GR G G AITF + K L +A ++ G +P + L
Sbjct: 523 PSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSILPPQLLN-SPYL 581
Query: 550 SKQKKKMIKKPLERESISTTPKCFLEKAKDKQKK---VTGQNSKKKVALEDKS 599
QK+K E+ KDKQ + VTG N + DKS
Sbjct: 582 HDQKRK-------------------EQQKDKQTQNDLVTGANLMDIIRKHDKS 615
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 213 bits (541), Expect = 5e-55
Identities = 154/477 (32%), Positives = 252/477 (52%), Gaps = 27/477 (5%)
Query: 100 QEEGATIQWMSSVEAKIED--KKVQRESKLTSG----KLENLRKEKINFLRNKHKIHVQG 153
+EEG ++W + A + K +ES TS + ++ RKE N + K +
Sbjct: 177 REEG--LKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLK-DGEK 233
Query: 154 TDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGS 213
+P+P TF D ++ +++NI AGFQ PTPIQ QA P++L G +L+ A TG+
Sbjct: 234 RPIPNPTCTF---DDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGT 290
Query: 214 GKTLAFSIPILMQLK-QPANKGFR----ALIISPTRELASQIHRELIKISEGTGFRIHMI 268
GKTL + +P + L QP+ KG R L+++PTRELA Q+ E K S G R +
Sbjct: 291 GKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSY-KGLRSVCV 349
Query: 269 HKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGK 328
+ ++ + K DI++ TP RL L Q ++L ++ +LV+DE+DK+ +
Sbjct: 350 YGGGNRDEQI-EELKKGVDIIIATPGRLNDL--QMSNFVNLKNITYLVLDEADKMLD--- 403
Query: 329 TGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNS-AVETVE 387
GF Q+ I L + + M SAT+ + V + + L + V +G + AV +V+
Sbjct: 404 MGFEPQIMKILLDVRPDR-QTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVK 462
Query: 388 QELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERT 447
Q ++ E L V+VFV A L +LI I+V+ +H +R
Sbjct: 463 QNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDRE 522
Query: 448 QQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAG 507
Q+ R+ + +F+ GK+ +LI T L +RG+D V V N+DFP + EY+HRIGRTGRAG
Sbjct: 523 QRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAG 582
Query: 508 NKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIKGF-QKLLSKQKKKMIKKPLER 563
G +IT T +D + + N++++A +PE + ++ + Q+K+ +++ +ER
Sbjct: 583 RTGVSITTLTRNDWRVASELINILERANQSIPEELVSMAERFKAHQQKREMERKMER 639
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 208 bits (529), Expect = 1e-53
Identities = 152/504 (30%), Positives = 257/504 (50%), Gaps = 64/504 (12%)
Query: 78 LTERKREQSK------KKRKTMTSEIASQEEGATIQWMSSVEAKIEDKKVQR--ESKLTS 129
L ++KREQS+ +KR+T+ + ++E A ++ + EAK QR + +
Sbjct: 309 LKQQKREQSRFYGDLMEKRRTLEEK---EQEEARLRKLRKKEAK------QRWDDRHWSQ 359
Query: 130 GKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPT 189
KL+ + R + I +G +P+PI +++ + + +L+ I G++ PT
Sbjct: 360 KKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWK----DSSLPPHILEVIDKCGYKEPT 415
Query: 190 PIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK--------QPANKGFRALIIS 241
PIQ QAIP+ L R+++ A TGSGKT AF IP+L+ + + +++G A+I++
Sbjct: 416 PIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILA 475
Query: 242 PTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLK 301
PTRELA QI E IK + G R + ++ + G + +I++ TP RLI +L+
Sbjct: 476 PTRELAQQIEEETIKFGKPLGIRTVAVI-GGISREDQGFRLRMGCEIVIATPGRLIDVLE 534
Query: 302 QDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIF---------------------- 339
+ L+ ++V+DE+D++ + GF + I
Sbjct: 535 NRY--LVLSRCTYVVLDEADRMID---MGFEPDVQKILEHMPVSNQKPDTDEAEDPEKML 589
Query: 340 --LACTSHKVRRA-MFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSE 396
HK R+ MF+AT VE+ + L V IG+ E VEQ++ F+ SE
Sbjct: 590 ANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKV-FLMSE 648
Query: 397 TGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVH 456
+ K + ++++GF+PP+++FV + L L G N +H + Q+QR+ +
Sbjct: 649 SEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALS 708
Query: 457 SFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFF 516
+ +AG +L+ T + RGID + V++V+NYD + +YIHRIGRTGRAG G AITF
Sbjct: 709 NLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFL 768
Query: 517 TEDDKPLLRSVANVIQQ---AGCP 537
T++D + + I + + CP
Sbjct: 769 TKEDSAVFYELKQAILESPVSSCP 792
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 207 bits (527), Expect = 2e-53
Identities = 167/557 (29%), Positives = 274/557 (49%), Gaps = 49/557 (8%)
Query: 7 FRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLD-FFGNKKSVPGVCGASQTH 65
+RR G G+ F F +G D D E +Q FG+++ V G T
Sbjct: 145 YRRGGRGS------FRGCRGGFGLGSPNNDLDPDECMQRTGGLFGSRRPVLSGTGNGDTS 198
Query: 66 QK------PQNGEK--KEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIE 117
Q + G K EE +T + K + + S S +G + ++ + E
Sbjct: 199 QSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGES---SDTQGPKVTYIPPPPPEDE 255
Query: 118 DKKVQR-ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRL 176
D ++ + K + + E V G D P I TF++ + +N+
Sbjct: 256 DSIFAHYQTGINFDKYDTILVE------------VSGHDAPPAILTFEEANLCQTLNN-- 301
Query: 177 LQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFR 236
NI AG+ TP+Q +IP++L GR+L+A A TGSGKT AF +PIL + R
Sbjct: 302 --NIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASR 359
Query: 237 --------ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
+I++PTREL +QI+ E K S GT R +I+ + + +I
Sbjct: 360 FKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIR-QIVQGCNI 418
Query: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 348
L TP RL+ ++ ++ G L +++LV+DE+D++ + G +L S + + +
Sbjct: 419 LCATPGRLMDIIGKEKIG--LKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQ 476
Query: 349 RAMFSATFAYDVEQWCKLNL-DNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELV 407
MFSATF ++++ L N + V++G A V+Q +L VG + K + E++
Sbjct: 477 TLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG-QFSKREKLVEIL 535
Query: 408 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467
+ + +VFV++ ++A + L E I+ IH +R Q++R+ + FR GK VL+
Sbjct: 536 RNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLV 595
Query: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFF-TEDDKPLLRS 526
T++ ARG+D + V VIN+D P++ EY+HRIGRTGR GN G+AI+FF E D L +
Sbjct: 596 ATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQP 655
Query: 527 VANVIQQAGCPVPEYIK 543
+ V+ A VP +++
Sbjct: 656 LVKVLTDAQQDVPAWLE 672
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 207 bits (527), Expect = 2e-53
Identities = 167/557 (29%), Positives = 274/557 (49%), Gaps = 49/557 (8%)
Query: 7 FRRLGAGAKFDTRRFSADAARFQIGKRKYDFDSSEVLQGLD-FFGNKKSVPGVCGASQTH 65
+RR G G+ F F +G D D E +Q FG+++ V G T
Sbjct: 145 YRRGGRGS------FRGCRGGFGLGSPNNDLDPDECMQRTGGLFGSRRPVLSGTGNGDTS 198
Query: 66 QK------PQNGEK--KEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIE 117
Q + G K EE +T + K + + S S +G + ++ + E
Sbjct: 199 QSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGES---SDTQGPKVTYIPPPPPEDE 255
Query: 118 DKKVQR-ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRL 176
D ++ + K + + E V G D P I TF++ + +N+
Sbjct: 256 DSIFAHYQTGINFDKYDTILVE------------VSGHDAPPAILTFEEANLCQTLNN-- 301
Query: 177 LQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKGFR 236
NI AG+ TP+Q +IP++L GR+L+A A TGSGKT AF +PIL + R
Sbjct: 302 --NIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASR 359
Query: 237 --------ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
+I++PTREL +QI+ E K S GT R +I+ + + +I
Sbjct: 360 FKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIR-QIVQGCNI 418
Query: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 348
L TP RL+ ++ ++ G L +++LV+DE+D++ + G +L S + + +
Sbjct: 419 LCATPGRLMDIIGKEKIG--LKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQ 476
Query: 349 RAMFSATFAYDVEQWCKLNL-DNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELV 407
MFSATF ++++ L N + V++G A V+Q +L VG + K + E++
Sbjct: 477 TLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVGGACRDVQQTVLQVG-QFSKREKLVEIL 535
Query: 408 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467
+ + +VFV++ ++A + L E I+ IH +R Q++R+ + FR GK VL+
Sbjct: 536 RNIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLV 595
Query: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFF-TEDDKPLLRS 526
T++ ARG+D + V VIN+D P++ EY+HRIGRTGR GN G+AI+FF E D L +
Sbjct: 596 ATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQP 655
Query: 527 VANVIQQAGCPVPEYIK 543
+ V+ A VP +++
Sbjct: 656 LVKVLTDAQQDVPAWLE 672
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 206 bits (524), Expect = 5e-53
Identities = 141/440 (32%), Positives = 232/440 (52%), Gaps = 34/440 (7%)
Query: 124 ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 183
E +L SG + EK + + + G++ P I F +D + ++ NI
Sbjct: 145 EQELFSGGNTGINFEKYDDI----PVEATGSNCPPHIENFSDID----MGEIIMGNIELT 196
Query: 184 GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 231
+ PTP+Q AIP++ R+L+A A TGSGKT AF +PIL Q+ K+
Sbjct: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256
Query: 232 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 286
G R +L+++PTRELA QI+ E K S + R +++ A ++ +
Sbjct: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 315
Query: 287 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 346
+LV TP RL+ ++++ G+D ++LV+DE+D++ + GF Q+ I T
Sbjct: 316 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 370
Query: 347 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 403
VR M FSATF +++ + LD I +++G S E + Q++++V + +
Sbjct: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430
Query: 404 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 463
L G + LVFV++ + A L L +EG IH +R+Q+ R+ +H FR+GK
Sbjct: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490
Query: 464 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 523
+L+ TA+ ARG+D V VIN+D P+ EY+HRIGRTGR GN G A +FF E + +
Sbjct: 491 PILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNI 550
Query: 524 LRSVANVIQQAGCPVPEYIK 543
+ + +++ +A VP +++
Sbjct: 551 TKDLLDLLVEAKQEVPSWLE 570
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 206 bits (524), Expect = 5e-53
Identities = 141/440 (32%), Positives = 232/440 (52%), Gaps = 34/440 (7%)
Query: 124 ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDA 183
E +L SG + EK + + + G++ P I F +D + ++ NI
Sbjct: 145 EQELFSGGNTGINFEKYDDI----PVEATGSNCPPHIENFSDID----MGEIIMGNIELT 196
Query: 184 GFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL------------KQPA 231
+ PTP+Q AIP++ R+L+A A TGSGKT AF +PIL Q+ K+
Sbjct: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256
Query: 232 NKGFR-----ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKF 286
G R +L+++PTRELA QI+ E K S + R +++ A ++ +
Sbjct: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLE-RGC 315
Query: 287 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 346
+LV TP RL+ ++++ G+D ++LV+DE+D++ + GF Q+ I T
Sbjct: 316 HLLVATPGRLVDMMERGKIGLDFC--KYLVLDEADRMLD---MGFEPQIRRIVEQDTMPP 370
Query: 347 --VRRAM-FSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAM 403
VR M FSATF +++ + LD I +++G S E + Q++++V + +
Sbjct: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLL 430
Query: 404 RELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKI 463
L G + LVFV++ + A L L +EG IH +R+Q+ R+ +H FR+GK
Sbjct: 431 DILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKS 490
Query: 464 WVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPL 523
+L+ TA+ ARG+D V VIN+D P+ EY+HRIGRTGR GN G A +FF E + +
Sbjct: 491 PILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNI 550
Query: 524 LRSVANVIQQAGCPVPEYIK 543
+ + +++ +A VP +++
Sbjct: 551 TKDLLDLLVEAKQEVPSWLE 570
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 206 bits (523), Expect = 6e-53
Identities = 137/405 (33%), Positives = 223/405 (55%), Gaps = 18/405 (4%)
Query: 149 IHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLAS 208
+ V G D P I TF++ + +N+ NI AG+ TP+Q +IP++L GR+L+A
Sbjct: 242 VEVSGHDAPPAILTFEEANLCQTLNN----NIAKAGYTKLTPVQKYSIPIILAGRDLMAC 297
Query: 209 APTGSGKTLAFSIPILMQLKQPANKGFR--------ALIISPTRELASQIHRELIKISEG 260
A TGSGKT AF +PIL + R +I++PTREL +QI+ E K S G
Sbjct: 298 AQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFG 357
Query: 261 TGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDES 320
T R +I+ + + +IL TP RL+ ++ ++ G L +++LV+DE+
Sbjct: 358 TCVRAVVIYGGTQLGHSIR-QIVQGCNILCATPGRLMDIIGKEKIG--LKQIKYLVLDEA 414
Query: 321 DKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNL-DNVISVSIGAR 379
D++ + G +L S + + + MFSATF ++++ L N + V++G
Sbjct: 415 DRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQV 474
Query: 380 NSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINV 439
A V+Q +L VG + K + E+++ + +VFV++ ++A + L E I+
Sbjct: 475 GGACRDVQQTVLQVG-QFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKIST 533
Query: 440 DVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHR 499
IH +R Q++R+ + FR GK VL+ T++ ARG+D + V VIN+D P++ EY+HR
Sbjct: 534 TSIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHR 593
Query: 500 IGRTGRAGNKGKAITFF-TEDDKPLLRSVANVIQQAGCPVPEYIK 543
IGRTGR GN G+AI+FF E D L + + V+ A VP +++
Sbjct: 594 IGRTGRCGNTGRAISFFDLESDNHLAQPLVKVLTDAQQDVPAWLE 638
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 205 bits (521), Expect = 1e-52
Identities = 144/467 (30%), Positives = 240/467 (51%), Gaps = 38/467 (8%)
Query: 101 EEGATIQWMSSVEAKIEDKKV----QRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDL 156
E G +W + K + + E +L SG + EK + + + G +
Sbjct: 120 ERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDI----PVEATGNNC 175
Query: 157 PDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKT 216
P I +F ++ + ++ NI + PTP+Q AIP++ R+L+A A TGSGKT
Sbjct: 176 PPHIESFSDVE----MGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKT 231
Query: 217 LAFSIPILMQL------------KQPANKGFR-----ALIISPTRELASQIHRELIKISE 259
AF +PIL Q+ K+ G R +L+++PTRELA QI+ E K S
Sbjct: 232 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 291
Query: 260 GTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDE 319
+ R +++ A ++ + +LV TP RL+ ++++ G+D ++LV+DE
Sbjct: 292 RSRVRPCVVYGGADIGQQIRDLE-RGCHLLVATPGRLVDMMERGKIGLDFC--KYLVLDE 348
Query: 320 SDKLFEDGKTGFRDQLASIFLACTSHK--VRRAM-FSATFAYDVEQWCKLNLDNVISVSI 376
+D++ + GF Q+ I T VR M FSATF +++ + LD I +++
Sbjct: 349 ADRMLD---MGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 405
Query: 377 GARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEG 436
G S E + Q++++V + + L G + LVFV++ + A L L +EG
Sbjct: 406 GRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEG 465
Query: 437 INVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEY 496
IH +R+Q+ R+ +H FR+GK +L+ TA+ ARG+D V VIN+D P+ EY
Sbjct: 466 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEY 525
Query: 497 IHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPEYIK 543
+HRIGRTGR GN G A +FF E + + + + +++ +A VP +++
Sbjct: 526 VHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLE 572
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 201 bits (511), Expect = 2e-51
Identities = 140/488 (28%), Positives = 249/488 (51%), Gaps = 28/488 (5%)
Query: 69 QNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDKKVQRESKLT 128
Q+ ++K E+ E +E+ K+ + + +A EG + + + I + S
Sbjct: 92 QHLKEKAEARKESAKEKQLKEEEKILESVA---EGRALMSVKEMAKGITYDDPIKTSWTP 148
Query: 129 SGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMP 188
+ ++ +E+ +R K+ I V+G +P PI +F+++ K + +L+ + G P
Sbjct: 149 PRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEM----KFPAAILRGLKKKGIHHP 204
Query: 189 TPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM-------QLKQPANKGFRALIIS 241
TPIQ+Q IP +L GR+++ A TGSGKTL F++P++M +L +G LII
Sbjct: 205 TPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIIC 264
Query: 242 PTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKK-----FDILVTTPNRL 296
P+RELA Q H L + + A+ K + ++V TP RL
Sbjct: 265 PSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRL 324
Query: 297 IYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATF 356
+ LL++ +D+ +L +DE+D++ + GF + +IF + + +FSAT
Sbjct: 325 MDLLQKKMVSLDIC--RYLALDEADRMID---MGFEGDIRTIFSYFKGQR-QTLLFSATM 378
Query: 357 AYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVL 416
++ + K L +++++G +A V QE+ +V E K++ + E ++K PPVL
Sbjct: 379 PKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYV-KEEAKMVYLLECLQKT-PPPVL 436
Query: 417 VFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGI 476
+F + + L+ +G+ IH + Q++R + +FR GK VL+ T + ++G+
Sbjct: 437 IFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGL 496
Query: 477 DFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTED-DKPLLRSVANVIQQAG 535
DF + VINYD P Y+HRIGRTGR+GN G A TF + D+ +L + ++ +A
Sbjct: 497 DFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAK 556
Query: 536 CPVPEYIK 543
VP ++
Sbjct: 557 QKVPPVLQ 564
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 195 bits (496), Expect = 9e-50
Identities = 149/547 (27%), Positives = 266/547 (48%), Gaps = 53/547 (9%)
Query: 72 EKKEESLTERKREQSKKKRKTMTSEIAS--------QEEGATIQWMSSVEAKIEDKKVQR 123
+K+ + + K E+ +KKRKT E S +EG+ + ++ E+
Sbjct: 110 KKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDE 169
Query: 124 --ESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLD-----QEYKINSRL 176
E+ +S L K ++++ K +G + Q D Q+ ++ L
Sbjct: 170 ASETDYSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPL 229
Query: 177 LQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPANKG-- 234
L+ I GF+ PTPIQ IPV L G+++ A A TG+GKT AF++P+L +L +
Sbjct: 230 LKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPV 289
Query: 235 FRALIISPTRELASQIHRELIKISEGTGFRIHMIH-----KAAVAAKKFGPKSSKKFDIL 289
R L++ PTREL Q+H ++++ + K+ AA + P DIL
Sbjct: 290 TRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAP------DIL 343
Query: 290 VTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRR 349
+ TP RLI L + P L+S+E L++DE+D++ ++ F +Q+ I C+ H+ +
Sbjct: 344 IATPGRLIDHL-HNCPSFHLSSIEVLILDEADRMLDEY---FEEQMKEIIRMCSHHR-QT 398
Query: 350 AMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFV--GSETGKLLAMRELV 407
+FSAT +V+ ++L N + + + + + QE + + E + + L+
Sbjct: 399 MLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAIVAALL 458
Query: 408 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467
+ F V++F Q+ ++A + L G+ V +H +Q QR + F+ +I +L+
Sbjct: 459 TRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILV 518
Query: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 527
T + ARG+D +GV VIN+ P + Y+HR+GRT RAG G++++ ED++ +L+
Sbjct: 519 ATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLK-- 576
Query: 528 ANVIQQAGCPV------PEYIKGFQKLLSKQKKKMI---------KKPLERESISTTPKC 572
+++ A PV + I F+ + K +K + K+ + E+ T K
Sbjct: 577 -EIVKAAKAPVKARILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKR 635
Query: 573 FLEKAKD 579
LEK K+
Sbjct: 636 LLEKGKE 642
>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
Length = 631
Score = 185 bits (470), Expect = 9e-47
Identities = 156/538 (28%), Positives = 255/538 (47%), Gaps = 54/538 (10%)
Query: 49 FGNKKSVPGVCGASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQW 108
FGN++ A +T + Q E S+ + Q+ R ++I + E + W
Sbjct: 96 FGNREMKAKAKAAIETLIRKQESYNSESSV-DNAASQTPIGRNLGRNDIVGEAEPLS-NW 153
Query: 109 MSSVEAKIEDKK--------VQR----ESKLTSGKLE----NLRKEKINFLRNKHKIHVQ 152
A +E +K V++ ESK TS E N RKE N + K +
Sbjct: 154 DRIRAAVVECEKRKWADLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEK 213
Query: 153 GTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTG 212
+P P F+ Q+Y LL++I+ G PTPIQ QA P++L G +L+ A TG
Sbjct: 214 RL-IPKPTCRFKDAFQQYP---DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTG 269
Query: 213 SGKTLAFSIPILMQL-KQPANKGFR----ALIISPTRELASQIHRELIKISEGTGFRIHM 267
+GKTL++ +P + L QP ++ R L+++PTRELA + E K S
Sbjct: 270 TGKTLSYLMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYS--------- 320
Query: 268 IHKAAVAAKKFGPKS--------SKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDE 319
+K + +G ++ SK DI++ TP RL L + ++L S+ +LV+DE
Sbjct: 321 -YKGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMNN--SVNLRSITYLVIDE 377
Query: 320 SDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGAR 379
+DK+ + F Q+ I L + + M SAT+ V Q L + + V +G
Sbjct: 378 ADKMLD---MEFEPQIRKILLDVRPDR-QTVMTSATWPDTVRQLALSYLKDPMIVYVGNL 433
Query: 380 NS-AVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGIN 438
N AV TV+Q ++ + + L + N V++FV A +L + +GI+
Sbjct: 434 NLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADDLSSDFNIQGIS 493
Query: 439 VDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIH 498
+ +H Q ++ V F++G I +LI T +++RG+D V V NYDFP + Y+H
Sbjct: 494 AESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVH 553
Query: 499 RIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPE--YIKGFQKLLSKQKK 554
R+G GR G G ++T T+ D + + ++ +A VPE + Q L++QK+
Sbjct: 554 RVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVMAEQYKLNQQKR 611
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 183 bits (464), Expect = 4e-46
Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%)
Query: 131 KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 190
++ NL +++ LR+K + V G P P ++F + + +L+ I + + PTP
Sbjct: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278
Query: 191 IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 246
IQ Q +PV L GR+++ A TGSGKT AF P+L+ Q + G A+I+ PTREL
Sbjct: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338
Query: 247 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 306
QIH E + + R ++ ++ + +I+V TP RLI +K+
Sbjct: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395
Query: 307 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 366
+L V +LV DE+D++F+ GF Q+ SI + + +FSATF +E+ +
Sbjct: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451
Query: 367 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 424
L + I V G A E V Q E+L G L R LV+ + VL+FV
Sbjct: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510
Query: 425 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 484
A+EL + L EG N+ ++H + Q +R+ + F+ I VL+ T + ARG+D + V
Sbjct: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570
Query: 485 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 520
INYD + HRIGRTGRAG KG A T T D
Sbjct: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 183 bits (464), Expect = 4e-46
Identities = 134/396 (33%), Positives = 202/396 (51%), Gaps = 18/396 (4%)
Query: 131 KLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTP 190
++ NL +++ LR+K + V G P P ++F + + +L+ I + + PTP
Sbjct: 223 EITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAH----FGFDEQLMHQIRKSEYTQPTP 278
Query: 191 IQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILM----QLKQPANKGFRALIISPTREL 246
IQ Q +PV L GR+++ A TGSGKT AF P+L+ Q + G A+I+ PTREL
Sbjct: 279 IQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTREL 338
Query: 247 ASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPG 306
QIH E + + R ++ ++ + +I+V TP RLI +K+
Sbjct: 339 CQQIHAECKRFGKAYNLRSVAVYGGGSMWEQ-AKALQEGAEIVVCTPGRLIDHVKKK--A 395
Query: 307 IDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKL 366
+L V +LV DE+D++F+ GF Q+ SI + + +FSATF +E+ +
Sbjct: 396 TNLQRVSYLVFDEADRMFD---MGFEYQVRSIASHVRPDR-QTLLFSATFRKKIEKLARD 451
Query: 367 NLDNVISVSIGARNSAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIER 424
L + I V G A E V Q E+L G L R LV+ + VL+FV
Sbjct: 452 ILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLT-RRLVEFTSSGSVLLFVTKKAN 510
Query: 425 AKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLV 484
A+EL + L EG N+ ++H + Q +R+ + F+ I VL+ T + ARG+D + V
Sbjct: 511 AEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTV 570
Query: 485 INYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDD 520
INYD + HRIGRTGRAG KG A T T D
Sbjct: 571 INYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKD 606
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 182 bits (463), Expect = 6e-46
Identities = 125/425 (29%), Positives = 221/425 (52%), Gaps = 23/425 (5%)
Query: 120 KVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDL-PDPIATFQQLDQEYKINSRLLQ 178
K ++ + ++ L +++ LR K +I V+G D+ P P+ F + ++
Sbjct: 129 KFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHAN----FPQYVMD 184
Query: 179 NILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK-QP---ANKG 234
++D F PTPIQ Q P+ L GR+++ A TGSGKTLA+ +P ++ + QP G
Sbjct: 185 VLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDG 244
Query: 235 FRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPN 294
L+++PTRELA Q+ + + + + I+ A + + +I + TP
Sbjct: 245 PICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE-RGVEICIATPG 303
Query: 295 RLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSA 354
RLI L+ +L +LV+DE+D++ + GF Q+ I + + M+SA
Sbjct: 304 RLIDFLESGKT--NLRRCTYLVLDEADRMLD---MGFEPQIRKIVDQIRPDR-QTLMWSA 357
Query: 355 TFAYDVEQWCKLNLDNVISVSIG-----ARNSAVETVEQELLFVGSETGKLLAMRELVKK 409
T+ +V Q + L + +++G A ++ ++ V+ + + KL+ + E +
Sbjct: 358 TWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVD--VCMESEKDHKLIQLMEEIMA 415
Query: 410 GFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICT 469
++FV++ R +L + +G IH +++Q +RD ++ FR+GK +LI T
Sbjct: 416 EKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIAT 475
Query: 470 ALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVAN 529
+ +RG+D + V VINYD+P SS +Y+HRIGRT R+ NKG A TFFT + R +
Sbjct: 476 DVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIK 535
Query: 530 VIQQA 534
V+++A
Sbjct: 536 VLEEA 540
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 182 bits (463), Expect = 6e-46
Identities = 125/425 (29%), Positives = 221/425 (52%), Gaps = 23/425 (5%)
Query: 120 KVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDL-PDPIATFQQLDQEYKINSRLLQ 178
K ++ + ++ L +++ LR K +I V+G D+ P P+ F + ++
Sbjct: 129 KFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHAN----FPQYVMD 184
Query: 179 NILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK-QP---ANKG 234
++D F PTPIQ Q P+ L GR+++ A TGSGKTLA+ +P ++ + QP G
Sbjct: 185 VLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDG 244
Query: 235 FRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPN 294
L+++PTRELA Q+ + + + + I+ A + + +I + TP
Sbjct: 245 PICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE-RGVEICIATPG 303
Query: 295 RLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSA 354
RLI L+ +L +LV+DE+D++ + GF Q+ I + + M+SA
Sbjct: 304 RLIDFLESGKT--NLRRCTYLVLDEADRMLD---MGFEPQIRKIVDQIRPDR-QTLMWSA 357
Query: 355 TFAYDVEQWCKLNLDNVISVSIG-----ARNSAVETVEQELLFVGSETGKLLAMRELVKK 409
T+ +V Q + L + +++G A ++ ++ V+ + + KL+ + E +
Sbjct: 358 TWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVD--VCMESEKDHKLIQLMEEIMA 415
Query: 410 GFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICT 469
++FV++ R +L + +G IH +++Q +RD ++ FR+GK +LI T
Sbjct: 416 EKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIAT 475
Query: 470 ALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVAN 529
+ +RG+D + V VINYD+P SS +Y+HRIGRT R+ NKG A TFFT + R +
Sbjct: 476 DVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIK 535
Query: 530 VIQQA 534
V+++A
Sbjct: 536 VLEEA 540
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 181 bits (460), Expect = 1e-45
Identities = 119/362 (32%), Positives = 192/362 (53%), Gaps = 13/362 (3%)
Query: 169 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 228
+ + LL+ I GF+ P+ IQ +AI + G +++A A +G+GKT F+I IL QL+
Sbjct: 37 DMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLE 96
Query: 229 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
K +AL+++PTRELA QI + ++ + + G H + ++ I
Sbjct: 97 IEF-KETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHI 155
Query: 289 LVTTPNRLIYLLKQDPPGIDLASVEWL---VVDESDKLFEDGKTGFRDQLASIFLACTSH 345
+V TP R+ +L + S +W+ V+DE+D++ GF+DQ+ IF +
Sbjct: 156 VVGTPGRVFDMLNRR-----YLSPKWIKMFVLDEADEMLS---RGFKDQIYEIFQKLNT- 206
Query: 346 KVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRE 405
++ + SAT DV + K + + I + + +E ++Q + V E KL + +
Sbjct: 207 SIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCD 266
Query: 406 LVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWV 465
L + ++F+ + + L ++ V +H + Q++RD + FR+G V
Sbjct: 267 LYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRV 326
Query: 466 LICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLR 525
LI T LLARGID + V+LVINYD PT+ YIHRIGR GR G KG AI F TE+DK +LR
Sbjct: 327 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 386
Query: 526 SV 527
+
Sbjct: 387 DI 388
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 179 bits (455), Expect = 5e-45
Identities = 116/375 (30%), Positives = 199/375 (53%), Gaps = 9/375 (2%)
Query: 168 QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL 227
++Y + LL I + G++ P+PIQ ++IP+ L GR++LA A G+GK+ A+ IP+L +L
Sbjct: 99 EDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERL 158
Query: 228 KQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFD 287
+ +A++I PTRELA Q+ + I++S+ G M + +
Sbjct: 159 DLKKDN-IQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 217
Query: 288 ILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKV 347
+++ TP R++ L+K+ +D V+ +V+DE+DKL F + I L ++
Sbjct: 218 VVIATPGRILDLIKKGVAKVD--HVQMIVLDEADKLLSQD---FVQIMEDIILTLPKNR- 271
Query: 348 RRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELV 407
+ ++SATF V+++ +L +++ ++ V Q +V +E K+ + L
Sbjct: 272 QILLYSATFPLSVQKFMNSHLQKPYEINL-MEELTLKGVTQYYAYV-TERQKVHCLNTLF 329
Query: 408 KKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467
+ ++F S +R + L ++ G + IHA+ Q+ R+ H FR G L+
Sbjct: 330 SRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLV 389
Query: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 527
CT L RGID + VN+VIN+DFP + Y+HRIGR+GR G+ G AI T DD+ L+S+
Sbjct: 390 CTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSI 449
Query: 528 ANVIQQAGCPVPEYI 542
+ P+P I
Sbjct: 450 EEQLGTEIKPIPSNI 464
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 177 bits (449), Expect = 2e-44
Identities = 116/359 (32%), Positives = 188/359 (52%), Gaps = 7/359 (1%)
Query: 169 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 228
+ ++ LL+ I GF+ P+ IQ +AI + G +++A A +G+GKT F+I IL Q++
Sbjct: 36 DMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIE 95
Query: 229 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
K +AL+++PTRELA QI + ++ + + G H + + I
Sbjct: 96 LDL-KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHI 154
Query: 289 LVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVR 348
+V TP R+ +L + + ++ V+DE+D++ GF+DQ+ IF S+ +
Sbjct: 155 IVGTPGRVFDMLNRRY--LSPKYIKMFVLDEADEMLS---RGFKDQIYDIFQKLNSN-TQ 208
Query: 349 RAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVK 408
+ SAT DV + K + + I + + +E + Q + V E KL + +L +
Sbjct: 209 VVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYE 268
Query: 409 KGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLIC 468
++F+ + + L ++ V +H + Q++RD + FR+G VLI
Sbjct: 269 TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLIT 328
Query: 469 TALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 527
T LLARGID + V+LVINYD PT+ YIHRIGR GR G KG AI TE+DK LR +
Sbjct: 329 TDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 175 bits (444), Expect = 9e-44
Identities = 116/387 (29%), Positives = 205/387 (52%), Gaps = 16/387 (4%)
Query: 150 HVQGTDLPDPIATFQQLD--QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLA 207
H T+ PI ++ ++ + L + G+ PT IQ++AIP+ L GR+++
Sbjct: 7 HDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIG 66
Query: 208 SAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHM 267
A TGSGKT AF++PIL L + + F AL+++PTRELA QI + + G + +
Sbjct: 67 LAETGSGKTGAFALPILNALLETPQRLF-ALVLTPTRELAFQISEQFEALGSSIGVQSAV 125
Query: 268 IHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDG 327
I + + +KK I++ TP RLI L ++ G +L ++++LV+DE+D++
Sbjct: 126 I-VGGIDSMSQSLALAKKPHIIIATPGRLIDHL-ENTKGFNLRALKYLVMDEADRILN-- 181
Query: 328 KTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVE 387
F ++ I + + +FSAT V++ + L N + ++ ++ VE ++
Sbjct: 182 -MDFETEVDKILKVIPRDR-KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQ 239
Query: 388 QELLFVGS---ETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHA 444
Q +F+ S +T + + EL F ++F + + L G +H
Sbjct: 240 QYYIFIPSKFKDTYLVYILNELAGNSF----MIFCSTCNNTQRTALLLRNLGFTAIPLHG 295
Query: 445 ERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTG 504
+ +Q +R +++ F+A +L+ T + +RG+D V++V+N+D PT S +YIHR+GRT
Sbjct: 296 QMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTA 355
Query: 505 RAGNKGKAITFFTEDDKPLLRSVANVI 531
RAG GKAITF T+ D L + + ++I
Sbjct: 356 RAGRSGKAITFVTQYDVELFQRIEHLI 382
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 172 bits (436), Expect = 8e-43
Identities = 123/404 (30%), Positives = 208/404 (51%), Gaps = 18/404 (4%)
Query: 138 EKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIP 197
+++ R +I V+G + P P+ F E + ++ I F PT IQ Q P
Sbjct: 71 QEVETYRRSKEITVRGHNCPKPVLNFY----EANFPANVMDVIARQNFTEPTAIQAQGWP 126
Query: 198 VMLHGRELLASAPTGSGKTLAFSIPILMQLK-QP---ANKGFRALIISPTRELASQIHRE 253
V L G +++ A TGSGKTL++ +P ++ + QP G L+++PTRELA Q+ +
Sbjct: 127 VALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQV 186
Query: 254 LIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVE 313
+ + I+ A + + +I + TP RLI L+ +L
Sbjct: 187 AAEYCRACRLKSTCIYGGAPKGPQIRDLE-RGVEICIATPGRLIDFLECGKT--NLRRTT 243
Query: 314 WLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVIS 373
+LV+DE+D++ + GF Q+ I + + M+SAT+ +V Q + L + I
Sbjct: 244 YLVLDEADRMLD---MGFEPQIRKIVDQIRPDR-QTLMWSATWPKEVRQLAEDFLKDYIH 299
Query: 374 VSIGARN-SAVETVEQ--ELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFH 430
++IGA SA + Q ++ + KL+ + E + +VFV++ R EL
Sbjct: 300 INIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTR 359
Query: 431 ELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFP 490
++ +G IH +++QQ+RD ++ F+ GK +LI T + +RG+D + V VINYD+P
Sbjct: 360 KMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYP 419
Query: 491 TSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQA 534
SS +YIHRIGRT R+ G A TFFT ++ + + +V+++A
Sbjct: 420 NSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREA 463
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 172 bits (435), Expect = 1e-42
Identities = 149/503 (29%), Positives = 243/503 (48%), Gaps = 39/503 (7%)
Query: 70 NGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDK-KVQRESKLT 128
NGE +S +++ KKKRK + ++ AK E+K K + ES T
Sbjct: 95 NGEAAMQSSNSESKKKKKKKRKMVNDAEPDTKK-----------AKTENKGKSEEESAET 143
Query: 129 SGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMP 188
+ + EN EK + ++ ++ L +N L+ I + GF
Sbjct: 144 TKETEN-NVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNM 202
Query: 189 TPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP---ILMQLKQPANKGFRALIISPTRE 245
T IQ ++I +L GR+LLA+A TGSGKTLAF IP ++++L+ G LI+SPTRE
Sbjct: 203 TEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTRE 262
Query: 246 LASQ---IHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQ 302
LA Q + +EL+ T I + A+K G +I+V TP RL+ + Q
Sbjct: 263 LAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLG----NGINIIVATPGRLLDHM-Q 317
Query: 303 DPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQ 362
+ PG +++ LV+DE+D++ + GF ++L I + + + +FSAT VE
Sbjct: 318 NTPGFMYKNLQCLVIDEADRILD---VGFEEELKQIIKLLPTRR-QTMLFSATQTRKVED 373
Query: 363 WCKLNLDN---VISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFV 419
+++L + V N+ V+ +EQ + SE + L + +KK ++VF
Sbjct: 374 LARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEK-RFLLLFTFLKKNRKKKLMVFF 432
Query: 420 QSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFK 479
S K + L Y + V IH ++ Q +R T F L+CT + ARG+D
Sbjct: 433 SSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIP 492
Query: 480 GVNLVINYDFPTSSVEYIHRIGRTGRAGN-KGKAITFFTEDDKPLLRSVANVIQQAGCPV 538
V+ ++ YD P EYIHR+GRT R N +G A+ ++ LR ++Q+ P+
Sbjct: 493 EVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLR----YLKQSKVPL 548
Query: 539 PEYIKGFQKL--LSKQKKKMIKK 559
E+ + K+ + Q +K+I+K
Sbjct: 549 SEFDFSWSKISDIQSQLEKLIEK 571
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 163 bits (413), Expect = 4e-40
Identities = 116/365 (31%), Positives = 184/365 (50%), Gaps = 15/365 (4%)
Query: 163 FQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP 222
FQ + Y + + I+ G+++PTPIQ + IPV+L G++++A A TGSGKT F +P
Sbjct: 98 FQSMGLSYPV----FKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLP 153
Query: 223 ILMQLK-QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPK 281
+ +LK A G RALI+SPTRELA Q + ++ + TG + +I +F
Sbjct: 154 MFERLKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAAL 213
Query: 282 SSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLA 341
DI++ TP RL+++ + + L SVE++V DE+D+LFE GF +QL I +A
Sbjct: 214 HENP-DIIIATPGRLVHVAVE--MSLKLQSVEYVVFDEADRLFE---MGFAEQLQEI-IA 266
Query: 342 CTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLL 401
+ +FSAT + ++ + L + + + E ++ V +T K
Sbjct: 267 RLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDT-KAA 325
Query: 402 AMRELVKKGFNPP--VLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFR 459
+ L+ P +VFV + A+ L L + ++ I++ R + F
Sbjct: 326 VLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFT 385
Query: 460 AGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTED 519
GK LI T L ARG+D ++ VINY FP ++HR+GR RAG G A + D
Sbjct: 386 LGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPD 445
Query: 520 DKPLL 524
+ P L
Sbjct: 446 EIPYL 450
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 163 bits (413), Expect = 4e-40
Identities = 116/365 (31%), Positives = 184/365 (50%), Gaps = 15/365 (4%)
Query: 163 FQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP 222
FQ + Y + + I+ G+++PTPIQ + IPV+L G++++A A TGSGKT F +P
Sbjct: 98 FQSMGLSYPV----FKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLP 153
Query: 223 ILMQLK-QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPK 281
+ +LK A G RALI+SPTRELA Q + ++ + TG + +I +F
Sbjct: 154 MFERLKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAAL 213
Query: 282 SSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLA 341
DI++ TP RL+++ + + L SVE++V DE+D+LFE GF +QL I +A
Sbjct: 214 HENP-DIIIATPGRLVHVAVE--MSLKLQSVEYVVFDEADRLFE---MGFAEQLQEI-IA 266
Query: 342 CTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLL 401
+ +FSAT + ++ + L + + + E ++ V +T K
Sbjct: 267 RLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLVREDT-KAA 325
Query: 402 AMRELVKKGFNPP--VLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFR 459
+ L+ P +VFV + A+ L L + ++ I++ R + F
Sbjct: 326 VLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFT 385
Query: 460 AGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTED 519
GK LI T L ARG+D ++ VINY FP ++HR+GR RAG G A + D
Sbjct: 386 LGKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPD 445
Query: 520 DKPLL 524
+ P L
Sbjct: 446 EIPYL 450
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 159 bits (403), Expect = 5e-39
Identities = 126/467 (26%), Positives = 225/467 (48%), Gaps = 33/467 (7%)
Query: 117 EDKKVQRESKLTSGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRL 176
++KK Q +L + + R+ ++N KI+V + I F ++ ++ +
Sbjct: 31 QNKKKQLRKQLKKPEWQVERESISRLMQNYEKINV------NEITRFS----DFPLSKKT 80
Query: 177 LQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPIL---MQLKQPANK 233
L+ + +A +++ T IQ Q I + L G+++L +A TGSGKTLAF +P+L +L+ +
Sbjct: 81 LKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTD 140
Query: 234 GFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSK--KFDILVT 291
G LIISPTRELA Q L K+ + F +I + K ++ + +ILV
Sbjct: 141 GLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLI----IGGKDLKHEAERINNINILVC 196
Query: 292 TPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAM 351
TP RL+ + + ++ LV+DE+D++ + GF D + ++ + K + +
Sbjct: 197 TPGRLLQHM-DETVSFHATDLQMLVLDEADRILD---MGFADTMNAV-IENLPKKRQTLL 251
Query: 352 FSATFAYDVEQWCKLNLDN--VISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKK 409
FSAT V+ +L+L N + V A+ S T+EQ + + K+ + ++
Sbjct: 252 FSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQ-KISVLYSFLRS 310
Query: 410 GFNPPVLVFVQSIERAKELFHEL--IYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLI 467
+VF S + + L+ + G+++ +H + Q +R + F + VL
Sbjct: 311 HLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAAVLF 370
Query: 468 CTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLRSV 527
T + ARG+DF VN V+ +D P + YIHR GRT R G+A+ +K +++
Sbjct: 371 ATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEKAMVQQ- 429
Query: 528 ANVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERESISTTPKCFL 574
+ Q PV E +KL+ QKK +++ +CF+
Sbjct: 430 ---LLQKKVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFV 473
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 157 bits (396), Expect = 3e-38
Identities = 107/384 (27%), Positives = 196/384 (51%), Gaps = 20/384 (5%)
Query: 148 KIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLA 207
K+ + ++ D TF + + LL+ I GF+ P+ IQ +AI ++ GR+++A
Sbjct: 25 KVEFETSEEVDVTPTFDTMG----LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIA 80
Query: 208 SAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHM 267
+ +G+GKT FSI +L L + +ALI++PTRELA QI + L+ + + + H
Sbjct: 81 QSQSGTGKTATFSISVLQCLDIQVRET-QALILAPTRELAVQIQKGLLALGDYMNVQCH- 138
Query: 268 IHKAAVAAKKFGPKSSKKFD----ILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKL 323
A + G + +K D ++ TP R+ ++++ + +++ LV+DE+D++
Sbjct: 139 ---ACIGGTNVG-EDIRKLDYGQHVVAGTPGRVFDMIRRR--SLRTRAIKMLVLDEADEM 192
Query: 324 FEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAV 383
G F++Q+ ++ + + SAT +++ + + + I + + +
Sbjct: 193 LNKG---FKEQIYDVYRYLPP-ATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTL 248
Query: 384 ETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIH 443
E ++Q + V E K + +L ++F + + L ++ V +H
Sbjct: 249 EGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMH 308
Query: 444 AERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRT 503
+ Q++R++ + FR+G VLI T + ARG+D V+L+INYD P + YIHRIGR+
Sbjct: 309 GDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRS 368
Query: 504 GRAGNKGKAITFFTEDDKPLLRSV 527
GR G KG AI F DD +LR +
Sbjct: 369 GRYGRKGVAINFVKNDDIRILRDI 392
>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
sapiens]
Length = 427
Score = 156 bits (395), Expect = 4e-38
Identities = 110/377 (29%), Positives = 187/377 (49%), Gaps = 8/377 (2%)
Query: 168 QEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL 227
+++ + LL+ I+D GF+ P+ +Q + IP + G ++L A +G GKT F + L Q+
Sbjct: 47 RDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQI 106
Query: 228 KQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFD 287
+P N L++ TRELA QI +E + S+ + ++ KK K
Sbjct: 107 -EPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCP 165
Query: 288 -ILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 346
++V TP R++ L++ L +V+ V+DE DK+ E + R + IF T H+
Sbjct: 166 HVVVGTPGRILALVRNR--SFSLKNVKHFVLDECDKMLE--QLDMRRDVQEIF-RLTPHE 220
Query: 347 VRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMREL 406
+ MFSAT + D+ C+ + + + V + Q+ ++ K + +L
Sbjct: 221 KQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDL 280
Query: 407 VKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVL 466
+ V++FV+S++R L L+ + IH Q++R + F+ + +L
Sbjct: 281 LDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRIL 340
Query: 467 ICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFT-EDDKPLLR 525
+ T L RG+D + VN+V NYD P S Y+HR+ R GR G KG AITF + E+D +L
Sbjct: 341 VATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILN 400
Query: 526 SVANVIQQAGCPVPEYI 542
V + + +PE I
Sbjct: 401 DVQDRFEVNVAELPEEI 417
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,558,663
Number of Sequences: 37866
Number of extensions: 968197
Number of successful extensions: 5551
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 105
Number of HSP's that attempted gapping in prelim test: 4685
Number of HSP's gapped (non-prelim): 726
length of query: 599
length of database: 18,247,518
effective HSP length: 108
effective length of query: 491
effective length of database: 14,157,990
effective search space: 6951573090
effective search space used: 6951573090
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.