Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 124378039
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|124378039 SEC16 homolog A [Homo sapiens]
(2357 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|124378039 SEC16 homolog A [Homo sapiens] 4853 0.0
gi|116235480 leucine zipper transcription regulator 2 [Homo sapi... 479 e-134
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 82 8e-15
gi|163965366 nascent polypeptide-associated complex alpha subuni... 81 1e-14
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 76 4e-13
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 76 4e-13
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 76 4e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 72 6e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 71 1e-11
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 70 2e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 66 4e-10
gi|110349719 titin isoform N2-A [Homo sapiens] 66 5e-10
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 66 5e-10
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 65 6e-10
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 65 6e-10
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 63 3e-09
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 62 7e-09
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 62 7e-09
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 62 7e-09
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 61 1e-08
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 60 3e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 60 3e-08
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 60 3e-08
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 60 3e-08
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 59 4e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 59 7e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens] 58 1e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 58 1e-07
gi|150378539 piccolo isoform 1 [Homo sapiens] 58 1e-07
gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming... 57 2e-07
>gi|124378039 SEC16 homolog A [Homo sapiens]
Length = 2357
Score = 4853 bits (12589), Expect = 0.0
Identities = 2357/2357 (100%), Positives = 2357/2357 (100%)
Query: 1 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 60
MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ
Sbjct: 1 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 60
Query: 61 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAH 120
ALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAH
Sbjct: 61 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAH 120
Query: 121 ASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMP 180
ASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMP
Sbjct: 121 ASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMP 180
Query: 181 GLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSG 240
GLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSG
Sbjct: 181 GLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSG 240
Query: 241 VPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPES 300
VPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPES
Sbjct: 241 VPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPES 300
Query: 301 TFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCA 360
TFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCA
Sbjct: 301 TFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCA 360
Query: 361 PLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGA 420
PLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGA
Sbjct: 361 PLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGA 420
Query: 421 GSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDP 480
GSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDP
Sbjct: 421 GSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDP 480
Query: 481 SSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQ 540
SSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQ
Sbjct: 481 SSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQ 540
Query: 541 ELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPT 600
ELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPT
Sbjct: 541 ELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPT 600
Query: 601 GIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLE 660
GIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLE
Sbjct: 601 GIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLE 660
Query: 661 QPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCES 720
QPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCES
Sbjct: 661 QPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCES 720
Query: 721 PATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQ 780
PATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQ
Sbjct: 721 PATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQ 780
Query: 781 SRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLA 840
SRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLA
Sbjct: 781 SRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLA 840
Query: 841 QPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPS 900
QPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPS
Sbjct: 841 QPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPS 900
Query: 901 SVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAG 960
SVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAG
Sbjct: 901 SVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAG 960
Query: 961 STSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQ 1020
STSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQ
Sbjct: 961 STSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQ 1020
Query: 1021 QSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSE 1080
QSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSE
Sbjct: 1021 QSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSE 1080
Query: 1081 LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPW 1140
LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPW
Sbjct: 1081 LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPW 1140
Query: 1141 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYR 1200
PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYR
Sbjct: 1141 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYR 1200
Query: 1201 PYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYASYY 1260
PYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYASYY
Sbjct: 1201 PYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYASYY 1260
Query: 1261 SSQYDYGDPGHWDRYHYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKRDNNWRY 1320
SSQYDYGDPGHWDRYHYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKRDNNWRY
Sbjct: 1261 SSQYDYGDPGHWDRYHYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKRDNNWRY 1320
Query: 1321 DPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIY 1380
DPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIY
Sbjct: 1321 DPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIY 1380
Query: 1381 RSHNVAAGSYEAPLPPGSFHGDFAYGTYRSNFSSGPGFPEYGYPADTVWPAMEQVSSRPT 1440
RSHNVAAGSYEAPLPPGSFHGDFAYGTYRSNFSSGPGFPEYGYPADTVWPAMEQVSSRPT
Sbjct: 1381 RSHNVAAGSYEAPLPPGSFHGDFAYGTYRSNFSSGPGFPEYGYPADTVWPAMEQVSSRPT 1440
Query: 1441 SPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQHTSEQEEMRAFPGP 1500
SPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQHTSEQEEMRAFPGP
Sbjct: 1441 SPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQHTSEQEEMRAFPGP 1500
Query: 1501 LAKDDTHKVDVINFAQNKAMKCLQNENLIDKESASLLWNFIVLLCRQNGTVVGTDIAELL 1560
LAKDDTHKVDVINFAQNKAMKCLQNENLIDKESASLLWNFIVLLCRQNGTVVGTDIAELL
Sbjct: 1501 LAKDDTHKVDVINFAQNKAMKCLQNENLIDKESASLLWNFIVLLCRQNGTVVGTDIAELL 1560
Query: 1561 LRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGGPAAAASSLERETER 1620
LRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGGPAAAASSLERETER
Sbjct: 1561 LRDHRTVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGGPAAAASSLERETER 1620
Query: 1621 FRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFANSLPINDPLQTVYQ 1680
FRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFANSLPINDPLQTVYQ
Sbjct: 1621 FRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFANSLPINDPLQTVYQ 1680
Query: 1681 LMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASRGLLDAAH 1740
LMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASRGLLDAAH
Sbjct: 1681 LMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASRGLLDAAH 1740
Query: 1741 FCYLMAQAGFGVYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAETCPLP 1800
FCYLMAQAGFGVYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAETCPLP
Sbjct: 1741 FCYLMAQAGFGVYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAETCPLP 1800
Query: 1801 SFQVFKFIYSCRLAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQLVQMASQLRLFDP 1860
SFQVFKFIYSCRLAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQLVQMASQLRLFDP
Sbjct: 1801 SFQVFKFIYSCRLAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQLVQMASQLRLFDP 1860
Query: 1861 QLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGL 1920
QLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGL
Sbjct: 1861 QLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGL 1920
Query: 1921 SQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPL 1980
SQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPL
Sbjct: 1921 SQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPL 1980
Query: 1981 EPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSE 2040
EPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSE
Sbjct: 1981 EPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSE 2040
Query: 2041 LSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETK 2100
LSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETK
Sbjct: 2041 LSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETK 2100
Query: 2101 EPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSM 2160
EPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSM
Sbjct: 2101 EPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSM 2160
Query: 2161 PKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAP 2220
PKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAP
Sbjct: 2161 PKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAP 2220
Query: 2221 LPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSS 2280
LPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSS
Sbjct: 2221 LPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSS 2280
Query: 2281 RPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPFYNPAQLAQACATS 2340
RPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPFYNPAQLAQACATS
Sbjct: 2281 RPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPFYNPAQLAQACATS 2340
Query: 2341 GSSRLGRIGQRKHLVLN 2357
GSSRLGRIGQRKHLVLN
Sbjct: 2341 GSSRLGRIGQRKHLVLN 2357
>gi|116235480 leucine zipper transcription regulator 2 [Homo sapiens]
Length = 1060
Score = 479 bits (1233), Expect = e-134
Identities = 342/972 (35%), Positives = 479/972 (49%), Gaps = 102/972 (10%)
Query: 1235 RQGYPEGYYSSKSGWSSQSDYYASYYSSQYDYGDPGHWDRYHYSARVRDPRTYDRRYWCD 1294
R GY Y S +S + Y SYY +G P W + R R P + Y
Sbjct: 100 RPGYENSYQSYQSPTMREEYAYGSYYY----HGHP-QWLQEERVPRQRSPYIWHEDYREQ 154
Query: 1295 AEYDA--YRREHSAFGDRPEKRDNNWRYDPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEH 1352
D Y +HS FG E + +P D P + G+E
Sbjct: 155 KYLDEHHYENQHSPFGTNSETHFQSNSRNP-----CKDSPASNS---GQEWPGELFPGSL 206
Query: 1353 SARSLHSAHSLASRRSSLSSHSHQSQIYRSHNVAAGSYEAPLPPGSFHGDFAYGTYRSNF 1412
A + + SLAS + L R +++ SYE
Sbjct: 207 LAEAQKNKPSLASESNLLQQ--------RESGLSSSSYELS----------------QYI 242
Query: 1413 SSGPGFPEYGYPADTVW-PAMEQVSSR-PTSPEKFSVPHVCARFGPGGQLIKVIPNLPSE 1470
P + PA W P VSS P +P KF +PHV FGPGGQL+ V P+ P++
Sbjct: 243 RDAPERDDP--PASAAWSPVQADVSSAGPKAPMKFYIPHVPVSFGPGGQLVHVGPSSPTD 300
Query: 1471 GQPALVEVHSMEALLQHTSEQEEMRAFPGPLAKDDTHKVDVINFAQNKAMKCLQNENLID 1530
GQ ALVE+HSME +L + EQEEMR+F GPL ++D HKVD++ F Q KA + ++E L
Sbjct: 301 GQAALVELHSMEVILNDSEEQEEMRSFSGPLIREDVHKVDIMTFCQQKAAQSCKSETLGS 360
Query: 1531 KESASLLWNFIVLLCRQNGTVVGTDIAELLLRDHRTVWLPGKSPNEANLIDFTNEAVEQV 1590
++SA LLW +VLLCRQNG++VG+DIAELL++D + + + P ANLI+ T+E +
Sbjct: 361 RDSA-LLWQLLVLLCRQNGSMVGSDIAELLMQDCKKLEKYKRQPPVANLINLTDEDWPVL 419
Query: 1591 EEEESGEAQLSFLTGGPAAAASSLERETERFRELLLYGRKKDALESAMKNGLWGHALLLA 1650
SG L LTG + + + E+F LL YGRKK+ALE AMKN LWGHAL L+
Sbjct: 420 S---SGTPNL--LTGEIPPSVETPAQIVEKFTRLLYYGRKKEALEWAMKNHLWGHALFLS 474
Query: 1651 SKMDSRTHARVMTRFANSLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLS 1710
SKMD +T++ VM+ F ++L +NDPLQT++QLMSGR+P A+TCCG+++WGDWRPHLA++LS
Sbjct: 475 SKMDPQTYSWVMSGFTSTLALNDPLQTLFQLMSGRIPQAATCCGEKQWGDWRPHLAVILS 534
Query: 1711 NLNNNMDVESRTMATMGDTLASRGLLDAAHFCYLMAQAGFGVYTKKTTKLVLIGSNHSLP 1770
N + ++ R + +GDTLA +GL++AAHFCYLMA FG YT KT LVL+GS+HS
Sbjct: 535 NQAGDPELYQRAIVAIGDTLAGKGLVEAAHFCYLMAHVPFGHYTVKTDHLVLLGSSHSQE 594
Query: 1771 FLKFATNEAIQRTEAYEYAQSLGAETCPLPSFQVFKFIYSCRLAEMGLATQAFHYCEAIA 1830
FLKFAT EAIQRTE +EY Q LG +PSFQV+K +Y+ RLA+ GL +QA HYCEAI
Sbjct: 595 FLKFATTEAIQRTEIFEYCQMLGRPKSFIPSFQVYKLLYASRLADYGLVSQALHYCEAIG 654
Query: 1831 KSILTQPHLYSPVLISQLVQMASQLRLFDPQLKEKPEEESLAAPTWLVHL-QQVERQIKE 1889
++L+Q PVL+ +L+++A +L+L DP + E+ + P WL L +Q+E+++
Sbjct: 655 AAVLSQGESSHPVLLVELIKLAEKLKLSDPLVLERRSGDRDLEPDWLAQLRRQLEQKVAG 714
Query: 1890 GAGVWHQDGALPQQCPGTPSSEMEQLDRPGL-SQPGALGIANPLLAVPAPSPEHSSPSVR 1948
G H + GT + D G A G + L P +
Sbjct: 715 DIGDPHPTRSDISGAGGTTTENTFYQDFSGCQGYSEAPGYRSALWLTP-------EQTCL 767
Query: 1949 LLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGC---VTPGPALGFLEPSGPGLPP 2005
L PS P P PL PG G G TP P E PG
Sbjct: 768 LQPS----------------PQQPFPLQPGSYPAGGGAGQTGTPRPFYSVPETHLPGTGS 811
Query: 2006 GVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTP-----SRTVP 2060
V + + E + P N++S+ + + DG+ P +R
Sbjct: 812 SVAVTEATGGTVWEEM-----LQTHLGPGENTVSQETSQPPDGQEVISKPQTPLAARPRS 866
Query: 2061 DSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTE 2120
SE+ + D + + T + G+ + G W F W K
Sbjct: 867 ISESSASSAKEDEKESSDEADKNSPRNTAQRGKLGDGKEHTKSSGFGW-FSWFRSK---- 921
Query: 2121 AYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVN 2180
KN S DE + + + EE +A P + ++ +P + PP V+
Sbjct: 922 ----PTKNASPAGDEDSS---DSPDSEETPRASSPHQAGLGLSLTPSPES---PPLPDVS 971
Query: 2181 MYSRRAAGTRAR 2192
+SR G R
Sbjct: 972 AFSRGRGGGEGR 983
Score = 39.3 bits (90), Expect = 0.046
Identities = 40/141 (28%), Positives = 59/141 (41%), Gaps = 18/141 (12%)
Query: 2224 PSNLFVPTPDAEEPQLPDG--TGREGPAAARGLA-----NPEPAPEPKVLSSAASLPGSE 2276
P+ P D + PD T R GL +PE P P V + + G E
Sbjct: 922 PTKNASPAGDEDSSDSPDSEETPRASSPHQAGLGLSLTPSPESPPLPDVSAFSRGRGGGE 981
Query: 2277 LPSSRPEG--SQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPS--GAMPFYNPAQ 2332
S G + G + S S+S E+ + PG L PP+ GA+P YNP+Q
Sbjct: 982 GRGSASSGGAAAGAGVGGLSGPESVSFELCSN----PGVLLP---PPALKGAVPLYNPSQ 1034
Query: 2333 LAQACATSGSSRLGRIGQRKH 2353
+ Q + +R R+ QR++
Sbjct: 1035 VPQLPTATSLNRPNRLAQRRY 1055
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 81.6 bits (200), Expect = 8e-15
Identities = 212/918 (23%), Positives = 303/918 (33%), Gaps = 143/918 (15%)
Query: 351 LGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLG 410
LGA G PL +G G G T E S+ +AG + A S
Sbjct: 47 LGAAGAVGRKPLAERAGGIG--------GATIPE---SAPRAGPTRSAGTS---SRNPAS 92
Query: 411 RPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEV 470
RPPA + PGP + G + T P G + + E V +
Sbjct: 93 RPPASGRGERAPPAKNTSPGPVSSP-----GRASGTTRPGPLGQKGLRISAEETVARGKA 147
Query: 471 LPSEPLNLDPSSPSDQFRYGPLPG---PAVPRHGAVCHTG------APDATLH--TVHPD 519
+ P S+ + + GP PG PA+ R T AP A T P
Sbjct: 148 TEA-PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206
Query: 520 SVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETT 579
SS S S S +AR + G +Q+ + ++ S P
Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP--------- 257
Query: 580 VSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETC 639
+ RG+ P+ PS PKP G+ + P + V P D A +G + +
Sbjct: 258 ---SARGTPRAPAHPSQPKPKGL------QALRPPQ-----VTPPRKDAAPALGPLSSSP 303
Query: 640 VRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDT 699
+ A P + PPDN T PLP P APP +
Sbjct: 304 L-------ATPSPSGTKARPVPPPDNAAT-------PLPATLPPSPPLATPLPLAPPSPS 349
Query: 700 VYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQ 759
P+ + PS P + TT Q A P+L P +Q
Sbjct: 350 APPSLQTLPSPPATPPSQAPPSMTTPPMQ--------------APPSLQTI-----PPIQ 390
Query: 760 PPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPP 819
P S PS A + A+ +L +P L ASL S P
Sbjct: 391 VPHSLTSPSLQAPPSPLA----LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTS--P 444
Query: 820 TESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDS 879
+ PP + P+ +SL S S A+ P S +
Sbjct: 445 SRPASTPPD-----------SPPLQAPLSLPASPPLQTSLSPAV---SPLSSPLTIHPLQ 490
Query: 880 GENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVP 939
++ S P + + SL +P QS+ A + PA+L PP + +P +L P
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSL-----APPSLQTPPASLTT-PPLENLP-SLAP 543
Query: 940 ESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLS 999
+ A P P + + PP+ T P ++ ++ AL
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603
Query: 1000 RTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQ 1059
+ L +P +P + + +A P Q+ P P T Q L A
Sbjct: 604 QGLPSPP--LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL--AVH 659
Query: 1060 ELVPPQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQS 1119
L P SPP P + S P S P A +Q+P SL Q+PP PP S
Sbjct: 660 LLQAP---FSPPPSPPVQ-APFSPPASPPVSPSATPPSQAPPSLAAPPL--QVPPSPPAS 713
Query: 1120 SSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYR--------PLYDAYQP 1171
+S ++ QA P P P VP P PP +A R PL P
Sbjct: 714 PPMSPSATPPPQAPPPLAAP-PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772
Query: 1172 QYSLPY-----PPEPGAASLYYQDVYSLYE-----PRYRPYDGAASAYAQNYRYPEPERP 1221
SLP PP +L + +L P P+ +AS P P+ P
Sbjct: 773 PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832
Query: 1222 SSRASHSSERPPPRQGYP 1239
A+ + PP P
Sbjct: 833 PVLAAPLLQVPPSPPASP 850
Score = 76.3 bits (186), Expect = 3e-13
Identities = 118/455 (25%), Positives = 148/455 (32%), Gaps = 77/455 (16%)
Query: 1900 LPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAP----SPEHSSPSVRLLPSAPQ 1955
LP P + L P L P PL A P+P PE S P AP
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPC-PLQAPPSPLTTPPPETPSSIATPPPQAPP 596
Query: 1956 TLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERR- 2014
L PL P+ P+ PP P P P L P PP PPL
Sbjct: 597 ALASPPLQGLPSPPLSPLATPP-PQAP--------PXLALPPLQAPPSPPASPPLSPLAT 647
Query: 2015 -----------HLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSE 2063
HLLQ SP P P +AP S + TP P S
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPS-PPVQAPFSPPASPPVS-------PSATPPSQAPPSL 699
Query: 2064 APPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYL 2123
A P S P PP+S S P + P A + P + + +
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA-------SPPMSPSAT 752
Query: 2124 PDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMP-----KTVQAAPPALPGPPGAP 2178
P + ++ + PP PP S+P K APPAL PP
Sbjct: 753 PPPRVPPLL-------------AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799
Query: 2179 VNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDA-EEP 2237
+ G P + P AP APL +P PS PT A P
Sbjct: 800 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP-PSPPASPTLQAPRRP 858
Query: 2238 QLP-DGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSSRPEGSQGGELSRCSSM 2296
P T GP LA P P P P S PSS G +L+ SS
Sbjct: 859 PTPGPDTSVSGPRLTLALA---PGPPP---------PPSRSPSST---LSGPDLAGHSSS 903
Query: 2297 SSLSREVSQHFNQAPGDLPAAGGPPSGAMPFYNPA 2331
++ + E + ++ P AA PP + +PA
Sbjct: 904 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 938
Score = 63.2 bits (152), Expect = 3e-09
Identities = 88/309 (28%), Positives = 111/309 (35%), Gaps = 53/309 (17%)
Query: 3 PPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPL--QPVTDPFAFSRQ 60
PPP+T PS +A PPP P AS P + +P PL P P +
Sbjct: 579 PPPET-PSSIATPPPQAPPA---LASPPLQ------GLPSPPLSPLATPPPQAPPXLALP 628
Query: 61 ALQSTPLGSSSKSSPPV--LQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPR 118
LQ+ P S +SPP+ L P+P Q P L H S P P+ P + P
Sbjct: 629 PLQAPP---SPPASPPLSPLATPSP----QAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681
Query: 119 A-----HASPFSGA----------LTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIP 163
+ A+P S A + PS P P M+ SA P + P + P P
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741
Query: 164 GVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWG------- 216
P S P +P PL P V P+ SLP L P
Sbjct: 742 PASPPMSPSATPPPRVP----PLLAAPPLQ--VPPSPPASLPMSPLAKPPPQAPPALATP 795
Query: 217 PVQGGPQPSGQHRSPCPEGPVPS--GVPCATSVPHFP--TPSILHQGPGHEQHSPLVAPP 272
P+Q P P P P S P AT P P + L Q P SP + P
Sbjct: 796 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855
Query: 273 AALPSDGRD 281
P+ G D
Sbjct: 856 RRPPTPGPD 864
Score = 62.4 bits (150), Expect = 5e-09
Identities = 105/430 (24%), Positives = 144/430 (33%), Gaps = 118/430 (27%)
Query: 1919 GLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAP----QTLPDG-------------- 1960
GL +P + +++ A P SP S PS R P AP Q P G
Sbjct: 233 GLQRPASRSLSSS--ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 1961 ------------PLA--SPARVPMFPVPLPPGPLEPGPGCVTPGPALGF---LEPSGPGL 2003
PLA SP+ PVP P P P + P P L L P P
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
Query: 2004 PPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSE 2063
PP LQ SP P P +AP PS T P +
Sbjct: 351 PPS----------LQTLPSP-PATPPSQAP---------------------PSMTTPPMQ 378
Query: 2064 APPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYL 2123
APP P Q P SL+ P A + S P + T ++L
Sbjct: 379 APPSLQTIP--PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS------PTLQATHSFL 430
Query: 2124 PDDKNKSIVWDEKKNQWVNLNEPEEEKKAPP-PPPTSMPKTVQAAPP------ALPGPPG 2176
++ +L P PP PP P ++ A+PP P
Sbjct: 431 TMSPRQT---------QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLS 481
Query: 2177 APVNMYSRRAAGTRARYVD-------VLNPSGTQRS--EPAL--APADFVAP-------L 2218
+P+ ++ +A + A + ++ P TQ S P+L PA P L
Sbjct: 482 SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL 541
Query: 2219 APLPI-PSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSEL 2277
AP P+ ++ + TP E P P P + +P P P+ SS A+ P
Sbjct: 542 APPPLQTASAPLTTPHLETPPCP------APCPLQAPPSPLTTPPPETPSSIATPPPQAP 595
Query: 2278 PSSRPEGSQG 2287
P+ QG
Sbjct: 596 PALASPPLQG 605
Score = 57.0 bits (136), Expect = 2e-07
Identities = 101/379 (26%), Positives = 140/379 (36%), Gaps = 34/379 (8%)
Query: 1966 ARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPD- 2024
AR P P PPG P P VTP AL L +G G PL ER + A P+
Sbjct: 19 ARAPGLLTPRPPGSPRPPPP-VTPA-ALRVLGAAG---AVGRKPLAERAGGIGGATIPES 73
Query: 2025 -PGIVPQEAPVGNSLSELSEENFDGKFANLTPSR-TVPDSEAPPGWDRADSGPTQP-PLS 2081
P P + +S + S G+ P++ T P + PG RA SG T+P PL
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG--RA-SGTTRPGPLG 130
Query: 2082 LSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWV 2141
+ A K T+ PK+ ++ T P + ++ +
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSA----LSAGARRDTSGPTPGTPSPAMA-RRSRAAGT 185
Query: 2142 NLNEPEEEKKAPPPPPTSMP-KTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPS 2200
+ P A P PPT P K+V +A P G + L+ S
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 2201 GTQRSEPALA-PADFVAPLAPL----PIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLA 2255
T S PA + P+ P AP P P L P P D GP ++ LA
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
Query: 2256 NPEPA-----PEPKVLSSAASLPGSELPS---SRPEGSQGGELSRCSSMSSLSREVSQHF 2307
P P+ P P ++A LP + PS + P S S+ +L +
Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPP 365
Query: 2308 NQAPGDLPAAGGPPSGAMP 2326
+QAP P+ PP A P
Sbjct: 366 SQAP---PSMTTPPMQAPP 381
Score = 56.2 bits (134), Expect = 4e-07
Identities = 110/431 (25%), Positives = 132/431 (30%), Gaps = 46/431 (10%)
Query: 3 PPPQTVPSGMAGP------PPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFA 56
PPPQ P P PPA P S SP +A N AV P P P
Sbjct: 617 PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP---QAPNALAVHLLQAPFSPPPSPPV 673
Query: 57 FSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQ 116
QA S P +SPPV P + P L P S P P P
Sbjct: 674 ---QAPFSPP------ASPPVSPSATPPSQAP-PSLAAPPLQVPPSP--PASPPMSPSAT 721
Query: 117 PRAHASPFSGA----LTPSAPPGPEMNRSAEVGPSSEPEVQTLP-YLPHYIPGVDPETSH 171
P A P A + PS P P M+ SA P P + P +P P P +
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL 781
Query: 172 GGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSP 231
P P L P + P P +P P L M P P
Sbjct: 782 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841
Query: 232 CPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSH 291
P P S A P P P GP L P P R S L SG
Sbjct: 842 VPPSPPASPTLQAPRRPPTPGPDTSVSGP----RLTLALAPGPPPPPSRSPSSTL-SGPD 896
Query: 292 LANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPL 351
LA +S ++ + R + +P E A +P A P
Sbjct: 897 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE----LAACHPAAWSRGPAPPLAFRG 952
Query: 352 GAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGR 411
GA P A G ++ ETE E+ + L D SPG
Sbjct: 953 APGAPLPWPPATGPGSADGLCTIY----ETEGPESATPAPGAL-------DPGPSPGTSG 1001
Query: 412 PPAPTHVGAGS 422
A GAG+
Sbjct: 1002 GKAAAGAGAGA 1012
Score = 55.5 bits (132), Expect = 6e-07
Identities = 187/826 (22%), Positives = 269/826 (32%), Gaps = 131/826 (15%)
Query: 90 PGLLVPHTHARDSSQGPCEPLPGPLTQPRA-----------------HASPFSGALTPSA 132
PGLL P P P P P P A A GA P +
Sbjct: 22 PGLLTPRP--------PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 133 PPGPEMNRSAEVG---PSSEPEV----QTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRP 185
P RSA P+S P + P + PG P +S G PG P
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG--PVSSPGRASGTTRPG---P 128
Query: 186 LSRQNPH--------DGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPV 237
L ++ G T A S G + GP G P P+ RS V
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS-GPTPGTPSPAMARRSRAAGTEV 187
Query: 238 PSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAA--LPSDGRD-----EVSHLQSGS 290
P ++ P PT +HS PAA PS G S S +
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 291 HLANNSDPESTFRQNPRIVNHWASPELR-----QNPGVKNEHRPASALVNPLARG----D 341
L++ + + R PR H + P+ + + P V + A+ + PL+
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 342 SPENRTHHPLGAGAGSGCAPLEADSGASGALAMFF-----QGGETENEENLSSEKAGLSG 396
SP P+ + PL A S LA + + L S A
Sbjct: 308 SPSGTKARPV-PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS 366
Query: 397 QADFDDFCSSPGLGRPPA----PTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDAS 452
QA ++P + PP+ P SL L P + A T S G P
Sbjct: 367 QA--PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424
Query: 453 GSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPA-VPRHGAVCHTGAPDA 511
+ + Q PS P + P SP Q PL PA P ++ +P +
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ---APLSLPASPPLQTSLSPAVSPLS 481
Query: 512 TLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPV 571
+ T+HP SS +S S PQ + + I P E S +P
Sbjct: 482 SPLTIHPLQALSSLASHS---------PQAPLSSLIM-----PPLETQSSLAPPSLQTPP 527
Query: 572 GGETDETTVS---------QNYRGSVSQPSTPSPPKPTGI---FQTSANSSFEPVKSHLV 619
T + Q ++ P +PP P S ++ P +
Sbjct: 528 ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587
Query: 620 GVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPP------DNMETLCAPQ 673
P +A A ++ + P A P +P L PP +P
Sbjct: 588 ATPPPQAPPALASPPLQG--LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL 645
Query: 674 VCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPD 733
P P AVH+L +PP AP P++ PV SP+ T +Q+ P
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS---PPV---SPSATPPSQAP-PS 698
Query: 734 FGGNVLLA----PAAPALYVCAKP----QPPVVQPPEEAMSGQQSRNP--SSAAPVQSRG 783
L PA+P + A P PP+ PP + + P SA P
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758
Query: 784 GIGASENLENPPKMGEEEALQSQASSGYAS--LLSSPPTESLQNPP 827
+ A+ L+ PP + A + L++PP ++L +PP
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804
Score = 55.5 bits (132), Expect = 6e-07
Identities = 185/817 (22%), Positives = 254/817 (31%), Gaps = 117/817 (14%)
Query: 42 APTTCPLQPVTDPFAFSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARD 101
AP+ P P P R+++ S S+++ SP + P+ G Q P A
Sbjct: 193 APSARPRPPTEGP----RKSVSSASEHSTTEPSPAARRRPSAGGGLQRP--------ASR 240
Query: 102 SSQGPCEPLPGPLTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHY 161
S PL P A + P S TP AP P + + P+V P
Sbjct: 241 SLSSSATPLSSP-----ARSGP-SARGTPRAPAHPSQPKPKGLQALRPPQVT--PPRKDA 292
Query: 162 IPGVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGG 221
P + P +S RP+ P D TP + P P L P P
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVP---PPDNAATPLPATLPPSPPLATPLPLAPPSPS 349
Query: 222 PQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGP----GHEQHSP-LVAPPAALP 276
PS Q P P PS P + + P P L P H SP L APP+ L
Sbjct: 350 APPSLQ-TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA 408
Query: 277 SDGRDEVSHL-----------------QSGSHLANNSDPESTFRQNPRI---VNHWASPE 316
+ L Q+ + L + S P ST +P + ++ ASP
Sbjct: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468
Query: 317 LRQ--NPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCAPLEADSG-ASGALA 373
L+ +P V P + ++PL S +H P + PLE S A +L
Sbjct: 469 LQTSLSPAVSPLSSPLT--IHPLQALSS--LASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
Query: 374 MFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSN 433
T ENL S A ++P L PP P + L P
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAP--LTTPHLETPPCPAPCPLQAPPSPLTTPPPE 582
Query: 434 EAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLP 493
+ T P A S +Q P PL P PL
Sbjct: 583 TPSSIA---TPPPQAPPALASPP--------LQGLPSPPLSPLATPPPQAPPXLALPPLQ 631
Query: 494 GPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGK 553
P P P + L T P + P L +Q
Sbjct: 632 APPSP------PASPPLSPLATPSPQA------------------PNALAVHLLQAPFSP 667
Query: 554 PEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEP 613
P + F S PV + T S++ P PP P S +++ P
Sbjct: 668 PPSPPVQAPFSPPASPPV---SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724
Query: 614 VKSHLVGVKPFEADRANVVGEVRETC------VRQKQCRPAAALPDASPGNL------EQ 661
+ P + + V P +P + P +L +
Sbjct: 725 QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784
Query: 662 PPDNMETLCAP--QVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRP-SARTQGPVKC 718
PP L P Q P P S P A P P P+ P A V
Sbjct: 785 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844
Query: 719 ESPAT-TLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAA 777
PA+ TL A P G + ++ L + P PP + P +SG SS+A
Sbjct: 845 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904
Query: 778 ---PVQSRGGIGASEN--LENPPKMGEEEALQSQASS 809
P + RG E +PP E A A S
Sbjct: 905 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 941
Score = 52.0 bits (123), Expect = 7e-06
Identities = 79/301 (26%), Positives = 97/301 (32%), Gaps = 59/301 (19%)
Query: 3 PPPQTVPSGMAGPP----PAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFS 58
P QT P+ + PP P+ P + AS+P + P CPLQ P
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT-PHLETPPCPAPCPLQAPPSPLT-- 577
Query: 59 RQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPR 118
P SS ++PP PA A P L QG P PL P
Sbjct: 578 ----TPPPETPSSIATPPPQAPPALAS----PPL-----------QGLPSPPLSPLATPP 618
Query: 119 AHASPF--------------SGALTPSAPPGPEMNRS-------AEVGPSSEPEVQTLPY 157
A P S L+P A P P+ + A P P VQ P+
Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA-PF 677
Query: 158 LPHYIPGVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGP 217
P P V P + P P L P + P P + + P P P P
Sbjct: 678 SPPASPPVSPSAT---PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734
Query: 218 VQGGPQPSGQHRSP--CPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAAL 275
+Q P P SP P P VP + P P P SPL PP
Sbjct: 735 LQVPPSPPA---SPPMSPSATPPPRVPPLLAAPPLQVPP---SPPASLPMSPLAKPPPQA 788
Query: 276 P 276
P
Sbjct: 789 P 789
Score = 49.7 bits (117), Expect = 3e-05
Identities = 106/440 (24%), Positives = 142/440 (32%), Gaps = 117/440 (26%)
Query: 1901 PQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDG 1960
PQ P + ++ P S P + P P P ++P +++ PS P +LP
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSPSATPP----PRVPPLLAAPPLQVPPSPPASLPMS 779
Query: 1961 PLASPARVPMFPVPLPPGPLE--PGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQ 2018
PLA P P P L PL+ P P PG A S P P PP Q L
Sbjct: 780 PLAKPP--PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837
Query: 2019 EARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQP 2078
VP P +P+ P PG D + SGP +
Sbjct: 838 PLLQ-----VPPSPPA-------------------SPTLQAPRRPPTPGPDTSVSGP-RL 872
Query: 2079 PLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKN 2138
L+L+P P P ++ P L G + P++ +D
Sbjct: 873 TLALAPGPPPP-PSRSPSSTLSGPD---------LAGHSSSATSTPEELRG---YD---- 915
Query: 2139 QWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLN 2198
+ PE A PPP + AA P PP + R A G
Sbjct: 916 -----SGPEGGAAASPPPDAELAACHPAAWSRGPAPP-----LAFRGAPG---------- 955
Query: 2199 PSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDG-------TGREGPAAA 2251
APLP P A P DG G E A
Sbjct: 956 --------------------APLP--------WPPATGPGSADGLCTIYETEGPESATPA 987
Query: 2252 RGLANPEPAPEPKVLSSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQH----- 2306
G +P P+P AA+ G+ S P+ ++ GEL + +L V QH
Sbjct: 988 PGALDPGPSPGTSG-GKAAAGAGAGASSRSPKQARLGEL----PLGALQASVVQHLLSRT 1042
Query: 2307 --FNQAPGDLPAAGGPPSGA 2324
A G +GG P GA
Sbjct: 1043 LLLAAAEGAAGGSGGGPGGA 1062
Score = 49.3 bits (116), Expect = 4e-05
Identities = 81/313 (25%), Positives = 102/313 (32%), Gaps = 43/313 (13%)
Query: 1 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRA------NNNAAVAPTTCP------- 47
++PP T P A P S SP +A +N A P T P
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLAT 339
Query: 48 ---LQPVTDPFAFSRQALQSTPLGSSSKSSPPVLQGP--APAGFSQHPGLLVPHTHARDS 102
L P + S Q L S P S++ P + P AP P + VPH+ S
Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS 399
Query: 103 SQGPCEPLP-GPLTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPS-------SEPEVQ- 153
Q P PL L + SP A P +++ PS P +Q
Sbjct: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA 459
Query: 154 --TLPYLPHYIPGVDPETSHGG-----HPHGNMPGLDRPLSRQNPHDGVVTPA--ASPSL 204
+LP P + P S HP + L S Q P ++ P SL
Sbjct: 460 PLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH-SPQAPLSSLIMPPLETQSSL 518
Query: 205 PQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQ 264
P LQ P P P S P + P T PH TP P
Sbjct: 519 APPSLQTP----PASLTTPPLENLPSLAPPPLQTASAPLTT--PHLETPPCPAPCPLQAP 572
Query: 265 HSPLVAPPAALPS 277
SPL PP PS
Sbjct: 573 PSPLTTPPPETPS 585
Score = 46.2 bits (108), Expect = 4e-04
Identities = 88/350 (25%), Positives = 118/350 (33%), Gaps = 53/350 (15%)
Query: 4 PPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQ---------PVTDP 54
PP P +A P P+ P S P + A + TT P+Q P+ P
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPP--ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392
Query: 55 FAFSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPL 114
+ + +LQ+ P + S +P + H L + + S P P P
Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452
Query: 115 TQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEP----EVQTLPYLPHYIPGVDPETS 170
P P L+ A P + + S V P S P +Q L L + P P +S
Sbjct: 453 DSP-----PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQA-PLSS 506
Query: 171 HGGHPHGNMPGLDRPLSRQNPHDGVVTPAAS--PSLPQPGLQMPGQWGPVQGGPQPSGQH 228
P L P S Q P + TP PSL P LQ S
Sbjct: 507 LIMPPLETQSSLAPP-SLQTPPASLTTPPLENLPSLAPPPLQTA------------SAPL 553
Query: 229 RSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQS 288
+P E P P PC P PS L P S PP A P+ + L S
Sbjct: 554 TTPHLETP-PCPAPCPLQAP----PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608
Query: 289 GSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLA 338
+ P P+ A P L+ P PAS ++PLA
Sbjct: 609 PPLSPLATPP-------PQAPPXLALPPLQAPPS-----PPASPPLSPLA 646
Score = 32.0 bits (71), Expect = 7.4
Identities = 46/155 (29%), Positives = 59/155 (38%), Gaps = 26/155 (16%)
Query: 1899 ALPQQCPGTPSSE--MEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQT 1956
+ P Q P +PS+ M L P P L A PLL VP PSP +SP+++ P
Sbjct: 806 SFPGQAPFSPSASLPMSPLATPPPQAPPVL--AAPLLQVP-PSPP-ASPTLQAPRRPPTP 861
Query: 1957 LPD--------------GPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGP- 2001
PD GP P+R P + P TP G+ SGP
Sbjct: 862 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY--DSGPE 919
Query: 2002 -GLPPGVPPLQERR--HLLQEARSPDPGIVPQEAP 2033
G PP E H +R P P + + AP
Sbjct: 920 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 954
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 80.9 bits (198), Expect = 1e-14
Identities = 227/1028 (22%), Positives = 337/1028 (32%), Gaps = 146/1028 (14%)
Query: 11 GMAGPPPAGNPRSVFWASSPYRRRANNN-----AAVAPTTCPLQPVTDPFAFSRQALQST 65
G A P P P +SSP + RA A+ +P P P P + +
Sbjct: 899 GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS 958
Query: 66 PLGSSSK--SSPPVLQG----PAPAGFSQHPGLLVPHTHARDSSQGPC-EPLPGPLTQPR 118
P + + ++PP +G P+P G P P ++ P P P +T P
Sbjct: 959 PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018
Query: 119 AHASPFS-----GALTPSA--PPGPEMNRSAEVGPSSEPEVQ--TLPYLPHYIPGVDPET 169
SP + GA TP A PP P+ + +A P P TLP P P
Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS-PKGGPATPSLK 1077
Query: 170 SHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWG----PVQGGPQPS 225
P P + +P + PAA+P P+ GL P G P P P
Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137
Query: 226 GQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSH 285
G +P P+G + P AT P P + P +P PP+ P G
Sbjct: 1138 GGLATPPPKGAPTT--PAAT--PPSPKGGLATPPPKGAPTTPAATPPS--PKGG------ 1185
Query: 286 LQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPEN 345
L + S + P +T +P+ SP+ P L P +G +P
Sbjct: 1186 LATPSPKGAPTTPAAT-PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG-APTT 1243
Query: 346 RTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCS 405
P G P + A +GG + A ++ + +
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303
Query: 406 SPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFV 465
SP G P P P P + G P + +
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS------- 1356
Query: 466 QNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSY 525
+ PS P + + + GP P P+ G + D T V P +S
Sbjct: 1357 KGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP--LSPKK 1414
Query: 526 SSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYR 585
+ + G+A P + ++ P S+P GG ++
Sbjct: 1415 APATPVTREGAATPSK-------GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 586 GSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQC 645
+V+ PS PP P + TS++ P +G
Sbjct: 1468 PAVTPPSPKEPPAPKQV-ATSSSPKKAPATPAPMGAPTL--------------------- 1505
Query: 646 RPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPE 705
A +P +SP + P + AP L+ T A A PP TV P+P+
Sbjct: 1506 --PAVIP-SSPKEVPATPSSRRDPIAPTA--TLLSKKTPATLAPKEALIPPAMTV-PSPK 1559
Query: 706 KRPSARTQGPVKCESPATTLWAQSELP------DFGG-----NVLLAPAAPALYVCAKPQ 754
K P+ P E+PAT ++ P + G +L+ PA + P
Sbjct: 1560 KTPAI----PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615
Query: 755 PPVVQPPEEAMSGQQSRNPSSAAP--VQSRGGIGASENLENPP-------KMGEEEALQS 805
PP V PP + P++ AP + + S ++P KMG A
Sbjct: 1616 PPAVTPP------SPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMG---ATVP 1666
Query: 806 QASSGYAS---------LLSSPPTESLQNPPVLIA------QPDHSYNLAQPINFSVSLS 850
QAS G + +L +P ES P++ A Q S + PI S
Sbjct: 1667 QASKGLPAKKGPTALKEVLVAPAPES---TPIITAPTRKGPQTKKSSATSPPICPDPSAK 1723
Query: 851 NSHEKNQSW--REALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFP 908
N + S L+ + S A G D+ + P S S L ++ + P
Sbjct: 1724 NGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP 1783
Query: 909 QGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVP 968
+ AS + P L PS PVP L P+ Q LP S S L P
Sbjct: 1784 KPESASVSAAPSPPVSLPLAPS-PVP-TLPPKQQ-------FLPSSPGLVLESPSKPLAP 1834
Query: 969 PAHGTLVP 976
L+P
Sbjct: 1835 ADEDELLP 1842
Score = 76.6 bits (187), Expect = 3e-13
Identities = 202/919 (21%), Positives = 294/919 (31%), Gaps = 178/919 (19%)
Query: 3 PPPQTVPSGMAGP----------PPAGNPRSVFWA-SSPYRRRANNNAAVAPTTCPLQPV 51
PP T PS GP PPA P S ++P + A AV P + P
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 52 TDPFAFSRQALQSTPLGS---SSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCE 108
PF STP + S K SP P P G P +P GP
Sbjct: 1025 ATPFPKGA----STPPAATPPSPKGSPAAT--PLPKGAPTTPAATLPSPKG-----GPAT 1073
Query: 109 P-LPGPLTQPRAHA-SPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYL-PHYIPGV 165
P L G T P A SP G TPS P G M +A PS + + T P+ P
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPS-PKGAPMPPAA-TPPSPKGGLATPPHKGAPTTPAA 1131
Query: 166 DPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWG----PVQGG 221
P + GG L+ P TPAA+P P+ GL P G P
Sbjct: 1132 TPPSPKGG------------LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179
Query: 222 PQPSGQHRSPCPEG------------------PVPSGVPCA-TSVPHFPTPSILHQGPGH 262
P P G +P P+G P P G P + P P + P
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239
Query: 263 EQHSPLVAP------PAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPE 316
+P P PA P G S + P NP +V P
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV---TPPS 1296
Query: 317 LRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCAPLEADSGASGALAMFF 376
+ P P A P A SP+ P GA + P G +
Sbjct: 1297 PKGGPATS---PPKGAPTPPAATPPSPKGSPGTPPPKGAPT--PPAVTPPSPKGTPTLPA 1351
Query: 377 QGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAA 436
++ S K G + A P + PP+P A +P P
Sbjct: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM-TPPSPKRGPA-------IPSPK---- 1399
Query: 437 GDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPA 496
GD S V S + + PS+ P+ + P +
Sbjct: 1400 ----GDPTSPAVIPLSP---KKAPATPVTREGAATPSKGDLTPPAVTPVSLK--KAPATS 1450
Query: 497 VPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPED 556
P+ G + D TL V P S + + +++ S+ P++ T
Sbjct: 1451 APKGGPATPSSKGDPTLPAVTPPSPKEPPAPK---QVATSSSPKKAPAT----------- 1496
Query: 557 EASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPS----PPKPTG-IFQTSANSSF 611
+P+G T + + + P+TPS P PT + ++
Sbjct: 1497 -----------PAPMGAPTLPAVIPSSPK---EVPATPSSRRDPIAPTATLLSKKTPATL 1542
Query: 612 EPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCA 671
P ++ + + + + + A++ P +P + P E L
Sbjct: 1543 APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602
Query: 672 PQV-CPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGP------------VKC 718
P V P P + T P +P PAP+ P++ P V C
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPP---SPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659
Query: 719 ESPATTLWAQSELPDFGG-----NVLLAPAAPALYVCAKP------------QPPVVQPP 761
+ AT A LP G VL+APA + + P P + P
Sbjct: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719
Query: 762 EEAMSGQQ----SRNPSSAAPVQ-----SRGGIGASENLENPPKMGEEEALQSQASSGYA 812
A +G + + P+ PVQ + G AS + + P E +A ++ +
Sbjct: 1720 PSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFE 1779
Query: 813 SLLSSPPTESLQ---NPPV 828
+L P + S+ +PPV
Sbjct: 1780 KVLPKPESASVSAAPSPPV 1798
Score = 67.8 bits (164), Expect = 1e-10
Identities = 243/1204 (20%), Positives = 372/1204 (30%), Gaps = 212/1204 (17%)
Query: 9 PSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQSTPLG 68
P G++ P P + ++ P N ++ V+P P + S Q + +P
Sbjct: 796 PLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPEN---SLSFQGSKDSPAT 852
Query: 69 SSSKSSPPVLQGPAPAGFS--QHPGLLVPHTHARDSS--------QGPCEPLPGPLT--- 115
+ S + P P P+ + G+ +P S +GP P P
Sbjct: 853 THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912
Query: 116 -------QPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPE 168
+ RA +P +PS P + P P + + P P P
Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP-PAATPP 971
Query: 169 TSHGGHPHGNMPGLDRP--LSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSG 226
+ GG + G P + +P G TP+ + P + P G P P G
Sbjct: 972 SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG 1031
Query: 227 QHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHL 286
P P P G P AT +P + +P P A LPS +
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLP---------------KGAP-TTPAATLPSPKGGPATPS 1075
Query: 287 QSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARG--DSPE 344
G+ + P S P+ SP+ P P L P +G +P
Sbjct: 1076 LKGAPTPPAATPPS-----PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
Query: 345 NRTHHPLGAGA-----GSGCAPLEADSGASGALAM-FFQGGETENEENLSSEKAGLSGQA 398
P G A G+ P G LA +G T S K GL+
Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA--- 1187
Query: 399 DFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYEN 458
P+ GA + A P P A + G P + +
Sbjct: 1188 ---------------TPSPKGAPTTPAATPPSPKGGLA-----TPSPKGAPTTPAATPPS 1227
Query: 459 VENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHP 518
+ + + P+ P PS P GPA P GAP T P
Sbjct: 1228 PKGGLATPSPKGAPTTPAATPPS---------PKGGPATPP-----PKGAPTPPAAT--P 1271
Query: 519 DSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDET 578
S+ ++ H G+ P V P G S P G T
Sbjct: 1272 PSLKGGLATPPH---KGAPNP----------AVVTPPSPKGG----PATSPPKGAPTPPA 1314
Query: 579 TVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRET 638
+ +GS P P P + S + + + K ++ G
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT-PTLPATTPSSKGGPTTPSSKEGPTPPA 1373
Query: 639 CVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPL-----PLNSTTEAVHMLPHAG 693
+ PA P G P T +P V PL P T P G
Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPT--SPAVIPLSPKKAPATPVTREGAATPSKG 1431
Query: 694 APPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKP 753
V P K+ A T P PAT P G+ P PA+ +
Sbjct: 1432 DLTPPAVTPVSLKKAPA-TSAPK--GGPAT--------PSSKGD----PTLPAVTPPSPK 1476
Query: 754 QPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPK-MGEEEALQSQASSGYA 812
+PP P + A S + P++ AP+ G + + PK + + + + A
Sbjct: 1477 EPPA--PKQVATSSSPKKAPATPAPM---GAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
Query: 813 SLLSS------PPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGD 866
+LLS P E+L P + + P + + P + S+ +
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP--------- 1582
Query: 867 RPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPAN--L 924
PAV+ ++ G P S L +P +V + + + P
Sbjct: 1583 -PAVTP----------STYKGAP--SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPA 1629
Query: 925 LVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHS 984
P P + P S KD SP SV G VP +K +
Sbjct: 1630 TPAPKGTPTSPPVTPSSLKD------------SPTSPASVTC---KMGATVPQASKGLPA 1674
Query: 985 SHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPN-------- 1036
++ + ++ E+ + P+ + S S P P A N
Sbjct: 1675 --KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732
Query: 1037 -----LDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQG 1091
L + +K A+G+ + L PP+ +AS P A L PES
Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPES----A 1788
Query: 1092 QAQNSAQSPASLVLVDAGQQLPPRPPQS----SSVSLVSSGSGQAAVPSEQPWPQPVPAL 1147
+ P SL L A +P PP+ SS LV + P+++ + +P +
Sbjct: 1789 SVSAAPSPPVSLPL--APSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE--DELLPLI 1844
Query: 1148 APGP 1151
P P
Sbjct: 1845 PPEP 1848
Score = 63.9 bits (154), Expect = 2e-09
Identities = 107/425 (25%), Positives = 148/425 (34%), Gaps = 63/425 (14%)
Query: 1931 PLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGP--GCVT 1988
P +P+P ++PS++ P+ P P P PA P+PP P P G T
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119
Query: 1989 PGPALGFLEPSGPGLPPGVP------PLQERRHLLQEARSPDP--GIV---PQEAPVGNS 2037
P P G P+ P P P P + A P P G+ P+ AP +
Sbjct: 1120 P-PHKG--APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176
Query: 2038 LSELSEENF----DGKFANLTPSRTVPDSE---APPGWDRADSGPTQPPLS-----LSPA 2085
+ S + K A TP+ T P + A P A + P P S +P+
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236
Query: 2086 PETKRPGQAAKKETKE------PKKGESWFFRWLPGKKKTEAYLPDDK---NKSIVWDEK 2136
P+ AA + + P KG P K P K N ++V
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV---- 1292
Query: 2137 KNQWVNLNEPEEEKKAP-PPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVD 2195
P K P PP P A PP+ G PG P + A T V
Sbjct: 1293 --------TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP----PPKGAPTPPA-VT 1339
Query: 2196 VLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLA 2255
+P GT + PA P+ P PS+ PTP A P G P+ RG A
Sbjct: 1340 PPSPKGTP-TLPATTPSSKGGPTT----PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394
Query: 2256 NPEPAPEPKVLSSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLP 2315
P P +P +S A +P S + ++ G + + +AP
Sbjct: 1395 IPSPKGDP---TSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA 1451
Query: 2316 AAGGP 2320
GGP
Sbjct: 1452 PKGGP 1456
Score = 58.9 bits (141), Expect = 6e-08
Identities = 101/412 (24%), Positives = 137/412 (33%), Gaps = 93/412 (22%)
Query: 1901 PQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDG 1960
P+ P TP++ S G L +P A P+ SP L +P+ P
Sbjct: 1168 PKGAPTTPAATPP-------SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220
Query: 1961 PLA------------SPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVP 2008
P A SP P P PP P + GP TP P G PP
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSP-KGGP--ATP-------PPKGAPTPPAAT 1270
Query: 2009 PLQERRHLLQEAR--SPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPP 2066
P + L +P+P +V +P G + K A P+ T P + P
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS------PPKGAPTPPAATPPSPKGSP 1324
Query: 2067 GWDRADSGPTQPPLSLSPAPE------TKRPGQAAKKETKEPKKGESWFFRWLPGKKKTE 2120
G PT PP P+P+ P T K+G +
Sbjct: 1325 GTPPPKGAPT-PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT-----------PP 1372
Query: 2121 AYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALP-GPPGAPV 2179
A P K + P K+ P P PK +P +P P AP
Sbjct: 1373 AATPSHKGGPAM------------TPPSPKRGPAIP---SPKGDPTSPAVIPLSPKKAPA 1417
Query: 2180 NMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADF-VAPLAPLP-----IPSNLFVPTPD 2233
+R A T PS + PA+ P AP P PS+ PT
Sbjct: 1418 TPVTREGAAT---------PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP 1468
Query: 2234 AEEPQLPDGTGREGPAAAR--GLANPEPAPEPKVLSSAASLPGSELPSSRPE 2283
A P P +E PA + ++P+ AP A +LP + +PSS E
Sbjct: 1469 AVTPPSP----KEPPAPKQVATSSSPKKAPATPAPMGAPTLP-AVIPSSPKE 1515
Score = 58.2 bits (139), Expect = 1e-07
Identities = 101/424 (23%), Positives = 137/424 (32%), Gaps = 58/424 (13%)
Query: 1901 PQQCPGTPSSEMEQLDRPGL-----SQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQ 1955
P++CP S G P LG++ SP+ P + + P
Sbjct: 767 PKECPTEDSGASATASSKGTLTYLADSPSPLGVS--------VSPQTKRPPTKKGSAGPD 818
Query: 1956 TLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPP--GVPPLQER 2013
T P G L+SP P+ LP L +P PS G P V PL +
Sbjct: 819 T-PIGNLSSPVS-PVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876
Query: 2014 RHLLQEARSPDPGIV----PQEAPVGNSLSE---LSEENFDGKFANLTPS-RTVPDSEAP 2065
L +P P +V P+E P + + LS + K A TP+ + +P S +P
Sbjct: 877 GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936
Query: 2066 PGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTE--AYL 2123
G A + P P S P T P A P + P T A
Sbjct: 937 KG---APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993
Query: 2124 PDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPP---------PPTSMPKTVQAAPPALPGP 2174
P K K P K +P PP + P + + +P A P P
Sbjct: 994 PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053
Query: 2175 PGAPVN-------------MYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPL 2221
GAP S + A T G P AP + P A
Sbjct: 1054 KGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP---MPPAATP 1110
Query: 2222 PIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSSR 2281
P P P P P T P+ GLA P P P ++ P L +
Sbjct: 1111 PSPKGGLATPPHKGAPTTPAAT---PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167
Query: 2282 PEGS 2285
P+G+
Sbjct: 1168 PKGA 1171
Score = 55.1 bits (131), Expect = 8e-07
Identities = 94/440 (21%), Positives = 144/440 (32%), Gaps = 80/440 (18%)
Query: 1934 AVPAPSPEHSSPSVRLLPSAPQTLPDGPL-----ASPARVPMFPVPLPPGPLEPGP---- 1984
A+P+P + +SP+V +P +P+ P P+ A+P++ + P + P L+ P
Sbjct: 1394 AIPSPKGDPTSPAV--IPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA 1451
Query: 1985 ---GCVTPG----PALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDP-------GIVPQ 2030
G TP P L + P P PP + + +P P ++P
Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511
Query: 2031 E---------------APVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGP 2075
AP LS+ + K A + P+ TVP + P P
Sbjct: 1512 SPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP 1571
Query: 2076 TQPPLSLSPAPETKRP----GQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSI 2131
P + +P P G + KE P S P K EA P
Sbjct: 1572 ATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTS------PSPK--EAPTPP------ 1617
Query: 2132 VWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRA 2191
+ P EK P P P + P +L P +P ++ + A
Sbjct: 1618 ----------AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667
Query: 2192 RYVDVLNPSG-TQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQL-PDGTGREGPA 2249
+ G T E +APA P+ P A P + PD + + G
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727
Query: 2250 AARGLANPEPAPEPKVLSSAASLPGSEL------PSSRPEGSQGGELSRCSSMSSLSREV 2303
P P P S+ + G + P + PE L+ + L +
Sbjct: 1728 GPLSTVAPAPL-LPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPE 1786
Query: 2304 SQHFNQAPG---DLPAAGGP 2320
S + AP LP A P
Sbjct: 1787 SASVSAAPSPPVSLPLAPSP 1806
Score = 54.3 bits (129), Expect = 1e-06
Identities = 87/361 (24%), Positives = 129/361 (35%), Gaps = 57/361 (15%)
Query: 1901 PQQCPGTPSSEMEQLDRPGLSQPGALGIANP--LLAVPA---PSPEHSSPSVRLLPSAPQ 1955
P++ P TPSS+ E P ++ G +P LL PA PSP+ + + P +P+
Sbjct: 1567 PKEAPATPSSK-EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
Query: 1956 TLP--DGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQER 2013
P P +P P+ P L P P G + + GLP P +
Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV---PQASKGLPAKKGPTALK 1682
Query: 2014 RHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADS 2073
L+ A P+ P+ ++ + + K ++ T PD A G
Sbjct: 1683 EVLVAPA--------PESTPI---ITAPTRKGPQTKKSSATSPPICPDPSAKNG----SK 1727
Query: 2074 GPTQPPLSLSPAPETKRPGQAAK-KETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIV 2132
GP P K + AK K+ KG P + K L + +
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL-----APPESKASTPLTAAAFEKV- 1781
Query: 2133 WDEKKNQWVNLNEPEEEK-KAPPPPPTSMP---KTVQAAPPA---LPGPPGAPVNMYSRR 2185
L +PE A P PP S+P V PP LP PG + S+
Sbjct: 1782 ----------LPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKP 1831
Query: 2186 AAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSN--LFVPTPDAEEPQLPDGT 2243
A + L P EP F + L +P P + + VPTP A++P +
Sbjct: 1832 LAPADEDELLPLIPP-----EPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNK 1886
Query: 2244 G 2244
G
Sbjct: 1887 G 1887
Score = 52.8 bits (125), Expect = 4e-06
Identities = 102/475 (21%), Positives = 158/475 (33%), Gaps = 77/475 (16%)
Query: 1905 PGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLAS 1964
P P S L + L +P L I P ++ +P +SS SV S GPL
Sbjct: 580 PEIPLSPEATLAKKSLGEP--LPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLK 637
Query: 1965 PARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPD 2024
+ + P +P T + G L + H ++E
Sbjct: 638 SSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTT 697
Query: 2025 PGIVP---QEAPVG----NSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRAD----- 2072
+VP + PV N+ + L+ + PS ++P + PPG + D
Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHT 757
Query: 2073 -------SGPTQ-------------------------PPLSLSPAPETKRPGQAAKKETK 2100
S P + PL +S +P+TKRP TK
Sbjct: 758 SALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP------PTK 811
Query: 2101 EPKKGESWFFRWL--PGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPT 2158
+ G L P ++LP++ S+ + K+ + P P P+
Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPEN---SLSFQGSKDSPATTHSPTPPSPKGAPTPS 868
Query: 2159 SM----PKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADF 2214
++ PK V P P P + A + L+ + + + PA
Sbjct: 869 AVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK 928
Query: 2215 VAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEP----APEPKVLSSAA 2270
P +P P + PTP A P P G GPA P P P PK +
Sbjct: 929 GIPASPSPKGA----PTPPAATPPSPKG----GPATPSPKWAPTPPAATPPSPKGGPATP 980
Query: 2271 SLPGSEL-PSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGA 2324
S G+ P++ P +GG + + V+ +P PAA P GA
Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP---PSPKGSPAATPFPKGA 1032
Score = 51.2 bits (121), Expect = 1e-05
Identities = 249/1234 (20%), Positives = 376/1234 (30%), Gaps = 173/1234 (14%)
Query: 9 PSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQSTPLG 68
P ++ P P ++ ++ ++ P T P P++ PL
Sbjct: 261 PGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPIS-------LGSHLAPLH 313
Query: 69 SSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCE-----PLPGPLTQPRAHASP 123
SS S +L P+ S + H+ + P + PLP A +
Sbjct: 314 QSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAA 373
Query: 124 FSGALTPSAPPGPEMNRSAEVGPSSEPEVQT---LPYLPHYIPGVDPETSHGGHPHGNMP 180
F + PS GP S PS V T L I P ++ MP
Sbjct: 374 FP-VVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMP 432
Query: 181 GLD---RPLSRQNPHDGVVTPAASPSLP---QPGLQMPGQWGPVQGGPQPSGQHRSPCPE 234
PL NP T AA+P+ + P GP+ S P
Sbjct: 433 VSSVGTTPLVVTNP----CTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPV 488
Query: 235 GPVPSGVPCATSV-----PHFPTPSILHQGPGH-----EQHSPLVAPPAALPSDGRDEVS 284
P AT++ P P P L P L PA+L S
Sbjct: 489 APKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGA---PFS 545
Query: 285 HLQSGSHLANNSDP------ESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLA 338
Q+G L DP ++ + +P + +SPE+ +P + +L PL
Sbjct: 546 PAQAG--LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKK---SLGEPLP 600
Query: 339 RGDSPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQA 398
G P + PLG + + ++ +G A + T E A +G A
Sbjct: 601 IG-KPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVA 659
Query: 399 DFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYEN 458
+S +P G SL P TAS P A Q
Sbjct: 660 PTTAKGTST-YTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQ--- 715
Query: 459 VENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHP 518
P L L P P +P P++P G T D HT
Sbjct: 716 ---------NTCAPLATLVLAPEIPKS------VPSPSLPPAGTPPGTKKVDGISHTSAL 760
Query: 519 DSVSSS------------YSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQI 566
V+SS ++ S G L+ A +G + + +P + +
Sbjct: 761 APVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAG---- 816
Query: 567 DSSPVGGETDETTV---------SQNYRGSVSQPST---PSPPKPTGIFQTSANSSFEPV 614
+P+G + + S +++GS P+T P+PP P G S+ P+
Sbjct: 817 PDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG---APTPSAVTPL 873
Query: 615 KSHLVGVKPFEADRANVVG----EVRETCVRQKQCRPAAALPDASP--GNLEQPPDNMET 668
V + P E +VV + KQ PA ++ +SP P +
Sbjct: 874 SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA-PALSMTSSSPKKARATPAPKGIPA 932
Query: 669 LCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPA---PEKRPSARTQGPVKCESPATTL 725
+P+ P P +T + P +P PA P + T P +P
Sbjct: 933 SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA-- 990
Query: 726 WAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMS------GQQSRNPSSAAPV 779
A P G PA P+ P PP V PP S + + P +A P
Sbjct: 991 -ATPPSPKGG------PATPS--PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041
Query: 780 QSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNL 839
+G A+ + P L S L PT PP P
Sbjct: 1042 SPKGSPAATPLPKGAPTT-PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100
Query: 840 AQPINFSVS-------LSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSS 892
P+ + + L+ K A P A G T+ + P S
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK-GGLATPPPKGAPTTPAATPPSP 1159
Query: 893 VLSLSLP-------SSVAQSNFPQGSGASEMVSNQPANLLVQPPS------------QPV 933
L+ P + A P+G A+ P PPS P
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219
Query: 934 PENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGA 993
P S K A + G +PA + PA T P G ++ G
Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA--TPPPKGAPTPPAATPPSLKGG 1277
Query: 994 LDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPG 1053
L + NP V PS + A+ P + P P +G PG
Sbjct: 1278 LATPPHKGAPNPAVVTPPS------PKGGPATSPPKGAPTPP------AATPPSPKGSPG 1325
Query: 1054 LERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLP 1113
+ PP P+ + + + + P ++ PA+ G +
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
Query: 1114 PRPPQSSSVSLVSSGSGQAAVPSEQPW-PQPVPA 1146
P P+ + S G P+ P P+ PA
Sbjct: 1386 PPSPKRGPA--IPSPKGDPTSPAVIPLSPKKAPA 1417
Score = 50.1 bits (118), Expect = 3e-05
Identities = 110/492 (22%), Positives = 162/492 (32%), Gaps = 99/492 (20%)
Query: 1901 PQQCPGTPSSE----MEQLDRPGLSQPGA----LGIANPLLAVPAPSPEHSSPSVRLLPS 1952
P+ P TPSS+ + + P +P A ++P A P+P + ++PS
Sbjct: 1452 PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511
Query: 1953 APQTLPDGPLASPARVPMFPVPL-----PPGPLEPGPGCVTPGPALGFLEPSGPGLPPGV 2007
+P+ +P P S R P+ P P L P + P + PS P P +
Sbjct: 1512 SPKEVPATP--SSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV----PS-PKKTPAI 1564
Query: 2008 PPLQE--RRHLLQEARSPDPGIVPQEAPVGNSLSEL----SEENFDGKFANLTPSRTVPD 2061
P +E +EA SP P + P S EL + + K A P+ T P
Sbjct: 1565 PTPKEAPATPSSKEASSP-PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS 1623
Query: 2062 SEAPPGWDRADSGPTQPPLS--------LSPAPETKRPGQAAKKETK--EPKKGESWFFR 2111
E P PT PP++ SPA T + G + +K KKG
Sbjct: 1624 PEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKG------ 1677
Query: 2112 WLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPP----------TSMP 2161
P K P ++ I+ + P+ +K + PP + P
Sbjct: 1678 --PTALKEVLVAPAPESTPIITAPTR------KGPQTKKSSATSPPICPDPSAKNGSKGP 1729
Query: 2162 KTVQAAPPALP----------------GPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRS 2205
+ A P LP P G S+ + A + + P S
Sbjct: 1730 LSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESAS 1789
Query: 2206 EPALAPADFVAPLAPLPIPS----NLFVPTPDA---EEPQLPDGTGREGPAAARGLANPE 2258
A PLAP P+P+ F+P+ E P P E L PE
Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP--LIPPE 1847
Query: 2259 P-------------APEPKVLSSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQ 2305
P P PK P ++ P ++ G E S+ L + S
Sbjct: 1848 PISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDST 1907
Query: 2306 HFNQAPGDLPAA 2317
L AA
Sbjct: 1908 QATTQQAQLAAA 1919
Score = 43.1 bits (100), Expect = 0.003
Identities = 64/264 (24%), Positives = 94/264 (35%), Gaps = 27/264 (10%)
Query: 3 PPPQTVPS---GMAGPPPAGNPRSVFWASSPYRRRANNNAAVA---PTTCPLQPVTDPFA 56
PP T PS G A P P G P S S + + A+V T P P
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675
Query: 57 FSRQALQSTPLGSSSKSSP----PVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPL-P 111
AL+ + + +S+P P +GP S + P A++ S+GP + P
Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAP 1735
Query: 112 GPLTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQ-TLPYLPHYIPGVDPETS 170
PL + +S + S P GP + PE + + P V P+
Sbjct: 1736 APLLPVQKDSSKTAKGKDASHSPK---------GPLAPPESKASTPLTAAAFEKVLPKPE 1786
Query: 171 HGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQ-PGLQMPGQWGPVQGGPQPSGQHR 229
P + PL+ P P LP PGL + P+ P +
Sbjct: 1787 SASVSAAPSPPVSLPLA---PSPVPTLPPKQQFLPSSPGLVLESPSKPL--APADEDELL 1841
Query: 230 SPCPEGPVPSGVPCATSVPHFPTP 253
P P+ GVP + + + PTP
Sbjct: 1842 PLIPPEPISGGVPFQSVLVNMPTP 1865
Score = 40.4 bits (93), Expect = 0.021
Identities = 99/469 (21%), Positives = 153/469 (32%), Gaps = 57/469 (12%)
Query: 7 TVPSGMAGP-PPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQST 65
T PS GP PPA P + A +P P P P S + +T
Sbjct: 1361 TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL--SPKKAPAT 1418
Query: 66 PLGSSSKSSP-----------PVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPL 114
P+ ++P PV APA + G P + + P P
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478
Query: 115 TQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPY-----LPHYIPGVDPET 169
P+ A+ S P+ P V PSS EV P + + +T
Sbjct: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538
Query: 170 SHGGHPHGNM--PGLDRPLSRQNPHDGVVTPAASPSLP------QPGLQMPGQWGPVQGG 221
P + P + P ++ P + TP +P+ P P P + +G
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTP--AIPTPKEAPATPSSKEASSPPAVTPSTY---KGA 1593
Query: 222 PQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRD 281
P P P P P P +V TP +GP P PS +D
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAV----TPPSPEKGPATPAPKGTPTSPPVTPSSLKD 1649
Query: 282 EVSHLQSGSHLANNSDPEST----FRQNPRIVNH-WASPELRQNPGVK------NEHRPA 330
+ S + + P+++ ++ P + +P P + + + +
Sbjct: 1650 SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709
Query: 331 SALVNPLARGDSPENRTHHPLGAGAGSGCAPLEADSG--ASGALAMFFQGGETENEENLS 388
SA P+ S +N + PL A + P++ DS A G A G E+ +
Sbjct: 1710 SATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKA 1769
Query: 389 S--------EKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLP 429
S EK ++ SP + P AP+ V Q LP
Sbjct: 1770 STPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLP 1818
Score = 36.2 bits (82), Expect = 0.39
Identities = 142/634 (22%), Positives = 210/634 (33%), Gaps = 110/634 (17%)
Query: 591 PSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAA 650
P + PK + FQ++++S P+ K + + G+ + +A+
Sbjct: 561 PLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPI-GKPASSMTSPLGVNSSAS 619
Query: 651 L--PDASPGNLEQPPDNMETLCAPQVCPLPLNS---------TTEAVHMLPHAGAPPLD- 698
+ D+ G P +L P V PL S T + +P L+
Sbjct: 620 VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEG 679
Query: 699 TVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVV 758
TV AP+ P VK E TTL +P N P AP+ P +V
Sbjct: 680 TVSLAPKNHP-------VK-EGTLTTL---PLVPTASEN---CPVAPSPQNTCAPLATLV 725
Query: 759 QPPEEAMSGQQSRNPSSAAPVQSRGGIGASEN------LENPPKMGEEE--ALQSQASSG 810
PE S P + P ++ G S +P + E+ A + +S G
Sbjct: 726 LAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKG 785
Query: 811 YASLLSSPPTE-------SLQNPPVL--IAQPDHSY-NLAQPINFSVSLSNSHEKNQSWR 860
+ L+ P+ + PP A PD NL+ P++ V S E + S++
Sbjct: 786 TLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVS-PVEASFLPENSLSFQ 844
Query: 861 EALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQ 920
+ D PA + S S G PT S ++ P V P + V N
Sbjct: 845 GSK--DSPATTH------SPTPPSPKGAPTPSAVTPLSPKGVT---LPPKETPTPSVVNL 893
Query: 921 PANLLVQPPSQPVPE-----NLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLV 975
P + P+ P P+ ++ S K +A A G SP S PPA
Sbjct: 894 P--FPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP--SPKGAPTPPAATPPS 949
Query: 976 PDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGP--- 1032
P G A S T A +P + S + + P + P
Sbjct: 950 PKGGPATPSPKWAPTPPA------------ATPPSPKGGPATPSPKGAPTPPAATPPSPK 997
Query: 1033 GAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQ 1092
G P T +G P + PP + SP P +G
Sbjct: 998 GGP--------ATPSPKGAP----TPPAVTPPSPKGSPAATPFP-------------KGA 1032
Query: 1093 AQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGP- 1151
+ A +P S A LP P + + +L S G A PS + P P A P P
Sbjct: 1033 STPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT-PSLKGAPTPPAATPPSPK 1091
Query: 1152 --PPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGA 1183
P P P+ L PP GA
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA 1125
Score = 34.3 bits (77), Expect = 1.5
Identities = 52/207 (25%), Positives = 75/207 (36%), Gaps = 34/207 (16%)
Query: 5 PQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTC-PLQPVTDPFAFSRQALQ 63
PQT S PP +P + + P + VAP P+Q + A + A
Sbjct: 1704 PQTKKSSATSPPICPDPSAKNGSKGPL-------STVAPAPLLPVQKDSSKTAKGKDASH 1756
Query: 64 ST--PLGS-SSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAH 120
S PL SK+S P+ A F + ++P + S P P+ PL
Sbjct: 1757 SPKGPLAPPESKASTPL----TAAAFEK----VLPKPESASVSAAPSPPVSLPLAPSPVP 1808
Query: 121 ASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMP 180
P PS+P + S + P+ E E+ LP +P PE GG P ++
Sbjct: 1809 TLPPKQQFLPSSPGLVLESPSKPLAPADEDEL--LPLIP-------PEPISGGVPFQSV- 1858
Query: 181 GLDRPLSRQNPHDGVVTPAASPSLPQP 207
L P +PS QP
Sbjct: 1859 -----LVNMPTPKSAGIPVPTPSAKQP 1880
Score = 33.9 bits (76), Expect = 1.9
Identities = 51/208 (24%), Positives = 77/208 (37%), Gaps = 38/208 (18%)
Query: 633 GEVRETCVRQKQCRP-----AAALPDASP----GNLEQPPDNMETLCAPQVCPLPLNSTT 683
GE ET +Q P A LP +S L QP + C+P PL++
Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62
Query: 684 EAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTL--WAQSELPDFGGNVLLA 741
+A + +P+P S + P S T L E P F N++
Sbjct: 63 QA-------------SPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGP 109
Query: 742 PAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQ--SRGGIGASENLENPPKMGE 799
P +PA A P++ P + PSS+AP+ + ++ PP +
Sbjct: 110 PISPAALALAS---PMIAPTLKG-------TPSSSAPLALVALAPHSVQKSSAFPPNLLT 159
Query: 800 EEALQSQASSGYASLLSSP--PTESLQN 825
+ A SG LS+P P+E N
Sbjct: 160 SPPSVAVAESGSVITLSAPIAPSEPKTN 187
Score = 32.3 bits (72), Expect = 5.6
Identities = 77/322 (23%), Positives = 111/322 (34%), Gaps = 58/322 (18%)
Query: 1899 ALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTL- 1957
ALP + + L P +S P AL +A+P++A SS + L+ AP ++
Sbjct: 90 ALPLGTAPEAPTFLPNLIGPPIS-PAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQ 148
Query: 1958 -----PDGPLASPARV------PMFPVPLPPGPLEPG------PGCVTPGPALGFLEPSG 2000
P L SP V + + P P EP P V P P PS
Sbjct: 149 KSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPK---GTPSP 205
Query: 2001 PGLPPGVPPLQERRHLLQEARSPDPGI--VPQEAPVGNSLSELSEENFDGKFANLTPSRT 2058
P + VP H + S G+ +PQ P +L+ S + D +++ S
Sbjct: 206 PCIVSTVP-----YHCVTPMASIQSGVASLPQTTPT-TTLAIASPQVKDTTISSVLISPQ 259
Query: 2059 VPDSEAPPGWDRADSGPTQPPLSLS---------------PAPETKRPGQAAKKETKEPK 2103
P S + GP PP +LS P T + P
Sbjct: 260 NPGS-------LSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPL 312
Query: 2104 KGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTS--MP 2161
S+ L G+ A L D K+I D + P + PP P + +P
Sbjct: 313 HQSSFGSVQLLGQTGPSA-LSDPTVKTISVDHSS---TGASYPSQRSVIPPLPSRNEVVP 368
Query: 2162 KTVQAAPPALPGPPGAPVNMYS 2183
TV A P P P + S
Sbjct: 369 ATVAAFPVVAPSVDKGPSTISS 390
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 75.9 bits (185), Expect = 4e-13
Identities = 101/429 (23%), Positives = 147/429 (34%), Gaps = 57/429 (13%)
Query: 1892 GVWHQDGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLP 1951
G + QD +P PG + + P PG + +P P P P P P
Sbjct: 131 GQYGQDLLIPPPPPGPAPGPPQDISEP----PGGSPLPSPPSTAPPPPPLLLEP-----P 181
Query: 1952 SAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQ 2011
P P P A P + P P P + P P L FL P P +P PP
Sbjct: 182 PPPSMAPPPPPVLEALSPPHTLSSPSIPTPPD--FIPPAPPLAFLAPPPPPVPAPAPPAP 239
Query: 2012 ERRHLLQEARSPDPGIVPQEAPVG--NSLSELSEENFDGKFANLTPSRTVPDSEAPPGWD 2069
H + P G+ ++ V +E + + A S P+ E +
Sbjct: 240 ASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFP 299
Query: 2070 RADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWF-----FRWLPGK-----KKT 2119
R+ P P+ S P + +A +KE KK S F P +
Sbjct: 300 RSFKVPPPTPVRTSSIP-VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAP 358
Query: 2120 EAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPV 2179
E P + + + Q + ++ +E PPP P P PPA P PP AP
Sbjct: 359 EPDCPGELKATAPASPRLGQ--SQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416
Query: 2180 NMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTP-DAEEPQ 2238
+++AA P+G ++ + +PA + P P P N P D +P
Sbjct: 417 LPCAQKAAHP---------PAGFTKTPKSSSPA--LKPKPNPPSPENTASSAPVDWRDPS 465
Query: 2239 LPD-----------GTGRE--------GPAAARGLANPEPAPEPKVLSSAASLPGSELPS 2279
+ G+ RE GP A + P + SLP + P
Sbjct: 466 QMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPP 525
Query: 2280 SRPEGSQGG 2288
PE S GG
Sbjct: 526 GVPEKSLGG 534
Score = 54.3 bits (129), Expect = 1e-06
Identities = 145/644 (22%), Positives = 210/644 (32%), Gaps = 109/644 (16%)
Query: 1 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 60
++PPP P MA PPP V A SP ++ + P P P
Sbjct: 178 LEPPP---PPSMAPPPPP-----VLEALSPPHTLSSPSIPTPPDFIPPAP---------- 219
Query: 61 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHP---GLLVPHTHARDSSQGPCEPLPGPLTQ- 116
PL + PPV PA S H L P + S T+
Sbjct: 220 -----PLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRA 274
Query: 117 --PRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPY-----LPHYIPGVD--- 166
PR+ A P AL P+ P RS +V P + ++P P G
Sbjct: 275 SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKA 334
Query: 167 ------PETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWG-PVQ 219
P + H P DR P + T ASP L Q Q + G P
Sbjct: 335 PSRLPLPPSFHIRPASQVYP--DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPP 392
Query: 220 GGPQPSGQHRSPCPEGPVPSG---VPCATSVPHFPTPSILHQGPGHEQHSPLVAPP---- 272
P P P P P+P +PCA H P P PP
Sbjct: 393 APPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPEN 452
Query: 273 --AALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPEL--RQNPGVKNEHR 328
++ P D RD + + LA R+ R ++H P + + G K
Sbjct: 453 TASSAPVDWRDPSQMEKLRNELAAYL---CGSRREDRFLSHRPGPTVAPQSKEGKKGPRL 509
Query: 329 PASALVNPLARGDSPENRTHHPLGAGAGSGCAPLE-ADSGASGALAMFFQGGETENEENL 387
P + L D+P LG GS E A S ++ Q T + +
Sbjct: 510 PEKETLLSLPAKDTPPGVPEKSLG---GSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQI 566
Query: 388 SSE-KAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTAST 446
+E +A LS A+ + + P +G P + G +C+ N A D +
Sbjct: 567 RNELEARLSSAAEKE---AKPSIGSLPPKPRLEGGRICE-------NGADDDKLSKPVAK 616
Query: 447 GVPDASGSQYENVENLEFVQNQEVLPSEPLN----LDPSSPSDQFRYGPLPGPAVPRHGA 502
+P Q+ +LP+ L L P+ P P PA+P
Sbjct: 617 NLPP---------------QSTTLLPTTSLQPKAMLGPAIPPK-----ATPEPAIPPKAT 656
Query: 503 VCHTGAPDATLHTVHPDSVSSS----YSSRSHGRLSGSARPQELVGTFIQQE-----VGK 553
+ P ATL P +S + S ++ +A + + E G+
Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716
Query: 554 PEDEASGSFFKQIDSSPVGGETDETTV-SQNYRGSVSQPSTPSP 596
PE AS + G ++ T + +Q R S + P SP
Sbjct: 717 PEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
Score = 50.1 bits (118), Expect = 3e-05
Identities = 121/479 (25%), Positives = 158/479 (32%), Gaps = 117/479 (24%)
Query: 1895 HQDGALPQQCPGTPSSEMEQLDRPGLSQPGA---LGIANPLLAVPAPSPEHSSPSVRLLP 1951
+ D A CPG + R G SQ A G P +P P+P P+ L P
Sbjct: 353 YPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPP 412
Query: 1952 SAPQTLPDG-----PLASPARVPMFPVP-LPPGPLEPGPGCVTPGPALGFLEPS------ 1999
+AP LP P A + P P L P P P P + + +PS
Sbjct: 413 AAPP-LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLR 471
Query: 2000 ---------------------GPGLPPGV------PPLQERRHLLQEARSPDPGIVPQEA 2032
GP + P P L E+ LL P VP+++
Sbjct: 472 NELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKS 531
Query: 2033 PVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPG 2092
G+SL+E PS T+P + P PT + E R
Sbjct: 532 LGGSSLTE----------TEAAPSLTLPSVDYIP-----QDSPTPSVRQIRNELEA-RLS 575
Query: 2093 QAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKA 2152
AA+KE K P G L G + E DDK L++P K
Sbjct: 576 SAAEKEAK-PSIGSLPPKPRLEGGRICENGADDDK---------------LSKP--VAKN 617
Query: 2153 PPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPA 2212
PP T++ T P A+ GP P +A + P T PA P
Sbjct: 618 LPPQSTTLLPTTSLQPKAMLGPAIPP-----------KATPEPAIPPKAT--LWPATPPK 664
Query: 2213 DFVAPLAPLPIPSNLFVPTPDAEEP-------QLPDGTGR------EGPA------AARG 2253
+ P PL S P P LP T + GPA A++
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
Query: 2254 LANPEPAPEPKVLSSAASLPGSELPSSR---PEGSQGGELSRC-----SSMSSLSREVS 2304
++ P A S A LP SS P+ S GG C SSLSREV+
Sbjct: 725 VSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVA 783
Score = 45.8 bits (107), Expect = 5e-04
Identities = 92/386 (23%), Positives = 129/386 (33%), Gaps = 98/386 (25%)
Query: 13 AGPPPAGNPRSVFWASSPYRRR---ANNNAAVAPTTCPLQPVTDP-FAFSRQALQST--- 65
A P PA P++ W ++P + A A + T PL+ + P A + L +T
Sbjct: 645 ATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQ 704
Query: 66 --------PLGSSSKSSPPVLQGPAPAGFSQHPG--LLVPHTHARDSSQGPCEPLPGP-- 113
P G K + + P+ A P +P AR S+ P + PG
Sbjct: 705 LMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGE 764
Query: 114 ---LTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPG------ 164
L +P H S S + A P + R GP EV+ P LP P
Sbjct: 765 VPCLYKPHCHQSSLSREV---AVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTD 821
Query: 165 ------VDPETSHGGHP----------------------HGNMPGLDRPLSRQNP--HDG 194
V E G P ++PG R S Q D
Sbjct: 822 ELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDS 881
Query: 195 VV----TP---AASPSLPQPG-------LQMPGQWGPVQG----GPQPSGQHR--SPCPE 234
+ TP P LP+ ++P +WGP G G + S +H P P+
Sbjct: 882 IFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQ 941
Query: 235 GPV----------PSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVS 284
PV P G P S P+PS + E + ++ PP +D
Sbjct: 942 APVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAP 1001
Query: 285 HLQSGSHLANNSDPE----STFRQNP 306
LQ +L S P S RQ P
Sbjct: 1002 ALQ---YLGRQSSPPRNNYSDLRQLP 1024
Score = 44.7 bits (104), Expect = 0.001
Identities = 220/1067 (20%), Positives = 331/1067 (31%), Gaps = 239/1067 (22%)
Query: 128 LTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRPLS 187
L P PPGP ++ S P LP P P P P P L
Sbjct: 138 LIPPPPPGPAPGPPQDI--SEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLE 195
Query: 188 RQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSV 247
+P + +SPS+P P +P P P +P P PVP+ P A +
Sbjct: 196 ALSPPHTL----SSPSIPTPPDFIP---------PAPPLAFLAP-PPPPVPAPAPPAPAS 241
Query: 248 PHFPTPSILHQGP-----------GHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNS 296
PH + G G + + +PP + P++ + GS L N
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRS-PAEPK--------GSALGPNP 292
Query: 297 DPESTFRQN-----PRIVNHWASPELRQNPGVKNEH----RPASALVNPLARGDSPENRT 347
+P TF ++ P V + P + E + S L P + P ++
Sbjct: 293 EPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQV 352
Query: 348 HHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSP 407
+ P A L+A + AS L G+++++ + E+AG A P
Sbjct: 353 Y-PDRAPEPDCPGELKATAPASPRL------GQSQSQ---ADERAGTPPPA--------P 394
Query: 408 GLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQN 467
L P P A L A P P + A T P +S + N
Sbjct: 395 PLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP--PAGFTKTPKSSSPALKPKPN------ 446
Query: 468 QEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATL-HTVHPDSVSSSYS 526
P P N S+P D + +C + D L H P S
Sbjct: 447 ----PPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE 502
Query: 527 SRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRG 586
+ RL L G PE GS + +++P
Sbjct: 503 GKKGPRLPEKETLLSLPAK--DTPPGVPEKSLGGSSLTETEAAP---------------- 544
Query: 587 SVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCR 646
S++ PS P Q S S +++ L E R + +K+ +
Sbjct: 545 SLTLPSVDYIP------QDSPTPSVRQIRNEL---------------EARLSSAAEKEAK 583
Query: 647 PAAALPDASP----GNLEQPPDNMETLCAPQVCPLPLNSTT-------EAVHML------ 689
P+ P G + + + + L P LP STT + ML
Sbjct: 584 PSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPP 643
Query: 690 ---PHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPA 746
P PP T++PA + + P+K S TT + P P +
Sbjct: 644 KATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTS 703
Query: 747 LYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQ 806
+ K P QP + A + + P Q+RG SE P
Sbjct: 704 QLMAEKDSGPAGQPEKPA-------SQEVSTPSQARGEGSPSEATRLP------------ 744
Query: 807 ASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGD 866
+ G S + PP S V H H+ + S A+V
Sbjct: 745 -TQGARSSAAFPPKTSPGGGEVPCLYKPH----------------CHQSSLSREVAVV-- 785
Query: 867 RPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPAN-LL 925
+ + A GG +G P + P G A S QP + LL
Sbjct: 786 ---MPTLARGGAAG------------------PGEPVEVKEPPGLPAKPPASAQPTDELL 824
Query: 926 VQPPSQPVPENLVP---------ESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVP 976
P + V E P +QK R G+AL G +S+
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAAL--------GRSSL------------ 864
Query: 977 DGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGP---- 1032
G+ +HS E + ++ S+ N V ++ P + GP
Sbjct: 865 PGSLRDHSHQAEASSDSIFH--SQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGR 922
Query: 1033 --GAPNLDRFYQQVTKDAQGQPGLERAQQELVP-----PQQQASPPQLPKAMFSELS--N 1083
L R + + Q ER +P P+ +SPP E N
Sbjct: 923 DAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFN 982
Query: 1084 PESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSG 1130
E +P + N + PA + Q PPR S L ++G G
Sbjct: 983 FEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPG 1029
Score = 42.7 bits (99), Expect = 0.004
Identities = 49/187 (26%), Positives = 59/187 (31%), Gaps = 11/187 (5%)
Query: 2152 APPPPPTSMPKTVQAAPPALPG----PPGAPVNMYSRRAAGTRARYVDVLNP--SGTQRS 2205
APPPPP P A P G PPG S A R +P S +
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 2206 EPALAPADFVAPLAPLPIPSNLFVPTPD-AEEPQLPDGTGREGPAAARGLANPEPAPEPK 2264
AL P P L P + VP P +P +E P G P+ P
Sbjct: 285 GSALGPN----PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPL 340
Query: 2265 VLSSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGA 2324
S P PE GEL + S + ++ G P A P A
Sbjct: 341 PPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPA 400
Query: 2325 MPFYNPA 2331
P PA
Sbjct: 401 PPLPPPA 407
Score = 35.8 bits (81), Expect = 0.51
Identities = 87/402 (21%), Positives = 145/402 (36%), Gaps = 54/402 (13%)
Query: 797 MGEEEALQSQASSGYASLLSSPPTESLQ--NPPVLIAQ--PDHSYNLAQPINFSVSLSNS 852
M +++ +Q S + ++ P+ SL NPP + Q P+ I + + N+
Sbjct: 1 MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT 60
Query: 853 -HEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSV------LSLSLPSSVAQS 905
E + +A RP ++ L EN L+ +PT SV ++ SS+
Sbjct: 61 VSESGTATLKARPRVRPLLTFLPLNAQ--ENHGLA-VPTPSVPDDFADKEVTGTSSLVNG 117
Query: 906 NFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVV 965
N S ++ Q L+ PP P P P+ + GS LP ++ ++
Sbjct: 118 NLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLL 177
Query: 966 LVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDS-LASQQSVA 1024
L PP ++ P + T S ++ P + P+ + LA
Sbjct: 178 LEPPPPPSMAPPPPPVLEALSPPHTLS------SPSIPTPPDFIPPAPPLAFLAPPPPPV 231
Query: 1025 SHPRQSGPGAPNL--DRFYQQ--VTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSE 1080
P P +P+ R + VTK + L Q E +ASPP+ P
Sbjct: 232 PAPAPPAPASPHTVGTRLFPPGGVTK-WKSDVALNGRQAEAT----RASPPRSPAEPKGS 286
Query: 1081 LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPW 1140
P P L + + PP P ++SS+ + + Q A E+
Sbjct: 287 ALGPNPEP-------------HLTFPRSFKVPPPTPVRTSSIPVQEA---QEAPRKEEGA 330
Query: 1141 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPG 1182
+ P+ P PP ++ RP Y + P P PG
Sbjct: 331 TKKAPSRLPLPPS------FHIRPASQVYPDR--APEPDCPG 364
Score = 35.4 bits (80), Expect = 0.67
Identities = 68/283 (24%), Positives = 92/283 (32%), Gaps = 78/283 (27%)
Query: 2058 TVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKK 2117
T P+ +AP W+R AP G K P
Sbjct: 936 TKPEPQAPVAWERV-------------APSNLPQGHPLPKSFSSP--------------- 967
Query: 2118 KTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPP-------- 2169
P NK +E+ N V PE PP P Q++PP
Sbjct: 968 ------PSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLR 1021
Query: 2170 ALP--GPPGAPVNMYSRRAAGTRARYVDVLNP-SGTQRSEPALAPADFVAPLAPLPIPSN 2226
LP GP P +SR AG R L SG RS I
Sbjct: 1022 QLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRS----------------LIKKR 1065
Query: 2227 LFVPTPDAEEPQLP-DGTGREGPAAARGLANPEP-APEPKVLSSAASLPGSELPSSRPEG 2284
L+V P P LP GTGR ++ P+P PE + ++SA P L + R
Sbjct: 1066 LYVGEPH-RGPGLPHGGTGRS--LSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPR--- 1119
Query: 2285 SQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPF 2327
S+ +R ++ ++APG P +G P+
Sbjct: 1120 ---------LSLEGAARGAAEAKHKAPGSADYGFAPAAGRSPY 1153
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 75.9 bits (185), Expect = 4e-13
Identities = 101/429 (23%), Positives = 147/429 (34%), Gaps = 57/429 (13%)
Query: 1892 GVWHQDGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLP 1951
G + QD +P PG + + P PG + +P P P P P P
Sbjct: 131 GQYGQDLLIPPPPPGPAPGPPQDISEP----PGGSPLPSPPSTAPPPPPLLLEP-----P 181
Query: 1952 SAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQ 2011
P P P A P + P P P + P P L FL P P +P PP
Sbjct: 182 PPPSMAPPPPPVLEALSPPHTLSSPSIPTPPD--FIPPAPPLAFLAPPPPPVPAPAPPAP 239
Query: 2012 ERRHLLQEARSPDPGIVPQEAPVG--NSLSELSEENFDGKFANLTPSRTVPDSEAPPGWD 2069
H + P G+ ++ V +E + + A S P+ E +
Sbjct: 240 ASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFP 299
Query: 2070 RADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWF-----FRWLPGK-----KKT 2119
R+ P P+ S P + +A +KE KK S F P +
Sbjct: 300 RSFKVPPPTPVRTSSIP-VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAP 358
Query: 2120 EAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPV 2179
E P + + + Q + ++ +E PPP P P PPA P PP AP
Sbjct: 359 EPDCPGELKATAPASPRLGQ--SQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416
Query: 2180 NMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTP-DAEEPQ 2238
+++AA P+G ++ + +PA + P P P N P D +P
Sbjct: 417 LPCAQKAAHP---------PAGFTKTPKSSSPA--LKPKPNPPSPENTASSAPVDWRDPS 465
Query: 2239 LPD-----------GTGRE--------GPAAARGLANPEPAPEPKVLSSAASLPGSELPS 2279
+ G+ RE GP A + P + SLP + P
Sbjct: 466 QMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPP 525
Query: 2280 SRPEGSQGG 2288
PE S GG
Sbjct: 526 GVPEKSLGG 534
Score = 54.3 bits (129), Expect = 1e-06
Identities = 145/644 (22%), Positives = 210/644 (32%), Gaps = 109/644 (16%)
Query: 1 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 60
++PPP P MA PPP V A SP ++ + P P P
Sbjct: 178 LEPPP---PPSMAPPPPP-----VLEALSPPHTLSSPSIPTPPDFIPPAP---------- 219
Query: 61 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHP---GLLVPHTHARDSSQGPCEPLPGPLTQ- 116
PL + PPV PA S H L P + S T+
Sbjct: 220 -----PLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRA 274
Query: 117 --PRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPY-----LPHYIPGVD--- 166
PR+ A P AL P+ P RS +V P + ++P P G
Sbjct: 275 SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKA 334
Query: 167 ------PETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWG-PVQ 219
P + H P DR P + T ASP L Q Q + G P
Sbjct: 335 PSRLPLPPSFHIRPASQVYP--DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPP 392
Query: 220 GGPQPSGQHRSPCPEGPVPSG---VPCATSVPHFPTPSILHQGPGHEQHSPLVAPP---- 272
P P P P P+P +PCA H P P PP
Sbjct: 393 APPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPEN 452
Query: 273 --AALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPEL--RQNPGVKNEHR 328
++ P D RD + + LA R+ R ++H P + + G K
Sbjct: 453 TASSAPVDWRDPSQMEKLRNELAAYL---CGSRREDRFLSHRPGPTVAPQSKEGKKGPRL 509
Query: 329 PASALVNPLARGDSPENRTHHPLGAGAGSGCAPLE-ADSGASGALAMFFQGGETENEENL 387
P + L D+P LG GS E A S ++ Q T + +
Sbjct: 510 PEKETLLSLPAKDTPPGVPEKSLG---GSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQI 566
Query: 388 SSE-KAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTAST 446
+E +A LS A+ + + P +G P + G +C+ N A D +
Sbjct: 567 RNELEARLSSAAEKE---AKPSIGSLPPKPRLEGGRICE-------NGADDDKLSKPVAK 616
Query: 447 GVPDASGSQYENVENLEFVQNQEVLPSEPLN----LDPSSPSDQFRYGPLPGPAVPRHGA 502
+P Q+ +LP+ L L P+ P P PA+P
Sbjct: 617 NLPP---------------QSTTLLPTTSLQPKAMLGPAIPPK-----ATPEPAIPPKAT 656
Query: 503 VCHTGAPDATLHTVHPDSVSSS----YSSRSHGRLSGSARPQELVGTFIQQE-----VGK 553
+ P ATL P +S + S ++ +A + + E G+
Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716
Query: 554 PEDEASGSFFKQIDSSPVGGETDETTV-SQNYRGSVSQPSTPSP 596
PE AS + G ++ T + +Q R S + P SP
Sbjct: 717 PEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
Score = 50.1 bits (118), Expect = 3e-05
Identities = 121/479 (25%), Positives = 158/479 (32%), Gaps = 117/479 (24%)
Query: 1895 HQDGALPQQCPGTPSSEMEQLDRPGLSQPGA---LGIANPLLAVPAPSPEHSSPSVRLLP 1951
+ D A CPG + R G SQ A G P +P P+P P+ L P
Sbjct: 353 YPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPP 412
Query: 1952 SAPQTLPDG-----PLASPARVPMFPVP-LPPGPLEPGPGCVTPGPALGFLEPS------ 1999
+AP LP P A + P P L P P P P + + +PS
Sbjct: 413 AAPP-LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLR 471
Query: 2000 ---------------------GPGLPPGV------PPLQERRHLLQEARSPDPGIVPQEA 2032
GP + P P L E+ LL P VP+++
Sbjct: 472 NELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKS 531
Query: 2033 PVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPG 2092
G+SL+E PS T+P + P PT + E R
Sbjct: 532 LGGSSLTE----------TEAAPSLTLPSVDYIP-----QDSPTPSVRQIRNELEA-RLS 575
Query: 2093 QAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKA 2152
AA+KE K P G L G + E DDK L++P K
Sbjct: 576 SAAEKEAK-PSIGSLPPKPRLEGGRICENGADDDK---------------LSKP--VAKN 617
Query: 2153 PPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPA 2212
PP T++ T P A+ GP P +A + P T PA P
Sbjct: 618 LPPQSTTLLPTTSLQPKAMLGPAIPP-----------KATPEPAIPPKAT--LWPATPPK 664
Query: 2213 DFVAPLAPLPIPSNLFVPTPDAEEP-------QLPDGTGR------EGPA------AARG 2253
+ P PL S P P LP T + GPA A++
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
Query: 2254 LANPEPAPEPKVLSSAASLPGSELPSSR---PEGSQGGELSRC-----SSMSSLSREVS 2304
++ P A S A LP SS P+ S GG C SSLSREV+
Sbjct: 725 VSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVA 783
Score = 45.8 bits (107), Expect = 5e-04
Identities = 92/386 (23%), Positives = 129/386 (33%), Gaps = 98/386 (25%)
Query: 13 AGPPPAGNPRSVFWASSPYRRR---ANNNAAVAPTTCPLQPVTDP-FAFSRQALQST--- 65
A P PA P++ W ++P + A A + T PL+ + P A + L +T
Sbjct: 645 ATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQ 704
Query: 66 --------PLGSSSKSSPPVLQGPAPAGFSQHPG--LLVPHTHARDSSQGPCEPLPGP-- 113
P G K + + P+ A P +P AR S+ P + PG
Sbjct: 705 LMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGE 764
Query: 114 ---LTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPG------ 164
L +P H S S + A P + R GP EV+ P LP P
Sbjct: 765 VPCLYKPHCHQSSLSREV---AVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTD 821
Query: 165 ------VDPETSHGGHP----------------------HGNMPGLDRPLSRQNP--HDG 194
V E G P ++PG R S Q D
Sbjct: 822 ELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDS 881
Query: 195 VV----TP---AASPSLPQPG-------LQMPGQWGPVQG----GPQPSGQHR--SPCPE 234
+ TP P LP+ ++P +WGP G G + S +H P P+
Sbjct: 882 IFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQ 941
Query: 235 GPV----------PSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVS 284
PV P G P S P+PS + E + ++ PP +D
Sbjct: 942 APVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAP 1001
Query: 285 HLQSGSHLANNSDPE----STFRQNP 306
LQ +L S P S RQ P
Sbjct: 1002 ALQ---YLGRQSSPPRNNYSDLRQLP 1024
Score = 44.7 bits (104), Expect = 0.001
Identities = 220/1067 (20%), Positives = 331/1067 (31%), Gaps = 239/1067 (22%)
Query: 128 LTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRPLS 187
L P PPGP ++ S P LP P P P P P L
Sbjct: 138 LIPPPPPGPAPGPPQDI--SEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLE 195
Query: 188 RQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSV 247
+P + +SPS+P P +P P P +P P PVP+ P A +
Sbjct: 196 ALSPPHTL----SSPSIPTPPDFIP---------PAPPLAFLAP-PPPPVPAPAPPAPAS 241
Query: 248 PHFPTPSILHQGP-----------GHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNS 296
PH + G G + + +PP + P++ + GS L N
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRS-PAEPK--------GSALGPNP 292
Query: 297 DPESTFRQN-----PRIVNHWASPELRQNPGVKNEH----RPASALVNPLARGDSPENRT 347
+P TF ++ P V + P + E + S L P + P ++
Sbjct: 293 EPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQV 352
Query: 348 HHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSP 407
+ P A L+A + AS L G+++++ + E+AG A P
Sbjct: 353 Y-PDRAPEPDCPGELKATAPASPRL------GQSQSQ---ADERAGTPPPA--------P 394
Query: 408 GLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQN 467
L P P A L A P P + A T P +S + N
Sbjct: 395 PLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP--PAGFTKTPKSSSPALKPKPN------ 446
Query: 468 QEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATL-HTVHPDSVSSSYS 526
P P N S+P D + +C + D L H P S
Sbjct: 447 ----PPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE 502
Query: 527 SRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRG 586
+ RL L G PE GS + +++P
Sbjct: 503 GKKGPRLPEKETLLSLPAK--DTPPGVPEKSLGGSSLTETEAAP---------------- 544
Query: 587 SVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCR 646
S++ PS P Q S S +++ L E R + +K+ +
Sbjct: 545 SLTLPSVDYIP------QDSPTPSVRQIRNEL---------------EARLSSAAEKEAK 583
Query: 647 PAAALPDASP----GNLEQPPDNMETLCAPQVCPLPLNSTT-------EAVHML------ 689
P+ P G + + + + L P LP STT + ML
Sbjct: 584 PSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPP 643
Query: 690 ---PHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPA 746
P PP T++PA + + P+K S TT + P P +
Sbjct: 644 KATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTS 703
Query: 747 LYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQ 806
+ K P QP + A + + P Q+RG SE P
Sbjct: 704 QLMAEKDSGPAGQPEKPA-------SQEVSTPSQARGEGSPSEATRLP------------ 744
Query: 807 ASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGD 866
+ G S + PP S V H H+ + S A+V
Sbjct: 745 -TQGARSSAAFPPKTSPGGGEVPCLYKPH----------------CHQSSLSREVAVV-- 785
Query: 867 RPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPAN-LL 925
+ + A GG +G P + P G A S QP + LL
Sbjct: 786 ---MPTLARGGAAG------------------PGEPVEVKEPPGLPAKPPASAQPTDELL 824
Query: 926 VQPPSQPVPENLVP---------ESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVP 976
P + V E P +QK R G+AL G +S+
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAAL--------GRSSL------------ 864
Query: 977 DGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGP---- 1032
G+ +HS E + ++ S+ N V ++ P + GP
Sbjct: 865 PGSLRDHSHQAEASSDSIFH--SQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGR 922
Query: 1033 --GAPNLDRFYQQVTKDAQGQPGLERAQQELVP-----PQQQASPPQLPKAMFSELS--N 1083
L R + + Q ER +P P+ +SPP E N
Sbjct: 923 DAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFN 982
Query: 1084 PESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSG 1130
E +P + N + PA + Q PPR S L ++G G
Sbjct: 983 FEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPG 1029
Score = 42.7 bits (99), Expect = 0.004
Identities = 49/187 (26%), Positives = 59/187 (31%), Gaps = 11/187 (5%)
Query: 2152 APPPPPTSMPKTVQAAPPALPG----PPGAPVNMYSRRAAGTRARYVDVLNP--SGTQRS 2205
APPPPP P A P G PPG S A R +P S +
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 2206 EPALAPADFVAPLAPLPIPSNLFVPTPD-AEEPQLPDGTGREGPAAARGLANPEPAPEPK 2264
AL P P L P + VP P +P +E P G P+ P
Sbjct: 285 GSALGPN----PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPL 340
Query: 2265 VLSSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGA 2324
S P PE GEL + S + ++ G P A P A
Sbjct: 341 PPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPA 400
Query: 2325 MPFYNPA 2331
P PA
Sbjct: 401 PPLPPPA 407
Score = 35.8 bits (81), Expect = 0.51
Identities = 87/402 (21%), Positives = 145/402 (36%), Gaps = 54/402 (13%)
Query: 797 MGEEEALQSQASSGYASLLSSPPTESLQ--NPPVLIAQ--PDHSYNLAQPINFSVSLSNS 852
M +++ +Q S + ++ P+ SL NPP + Q P+ I + + N+
Sbjct: 1 MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT 60
Query: 853 -HEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSV------LSLSLPSSVAQS 905
E + +A RP ++ L EN L+ +PT SV ++ SS+
Sbjct: 61 VSESGTATLKARPRVRPLLTFLPLNAQ--ENHGLA-VPTPSVPDDFADKEVTGTSSLVNG 117
Query: 906 NFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVV 965
N S ++ Q L+ PP P P P+ + GS LP ++ ++
Sbjct: 118 NLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLL 177
Query: 966 LVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDS-LASQQSVA 1024
L PP ++ P + T S ++ P + P+ + LA
Sbjct: 178 LEPPPPPSMAPPPPPVLEALSPPHTLS------SPSIPTPPDFIPPAPPLAFLAPPPPPV 231
Query: 1025 SHPRQSGPGAPNL--DRFYQQ--VTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSE 1080
P P +P+ R + VTK + L Q E +ASPP+ P
Sbjct: 232 PAPAPPAPASPHTVGTRLFPPGGVTK-WKSDVALNGRQAEAT----RASPPRSPAEPKGS 286
Query: 1081 LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPW 1140
P P L + + PP P ++SS+ + + Q A E+
Sbjct: 287 ALGPNPEP-------------HLTFPRSFKVPPPTPVRTSSIPVQEA---QEAPRKEEGA 330
Query: 1141 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPG 1182
+ P+ P PP ++ RP Y + P P PG
Sbjct: 331 TKKAPSRLPLPPS------FHIRPASQVYPDR--APEPDCPG 364
Score = 35.4 bits (80), Expect = 0.67
Identities = 68/283 (24%), Positives = 92/283 (32%), Gaps = 78/283 (27%)
Query: 2058 TVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKK 2117
T P+ +AP W+R AP G K P
Sbjct: 936 TKPEPQAPVAWERV-------------APSNLPQGHPLPKSFSSP--------------- 967
Query: 2118 KTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPP-------- 2169
P NK +E+ N V PE PP P Q++PP
Sbjct: 968 ------PSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLR 1021
Query: 2170 ALP--GPPGAPVNMYSRRAAGTRARYVDVLNP-SGTQRSEPALAPADFVAPLAPLPIPSN 2226
LP GP P +SR AG R L SG RS I
Sbjct: 1022 QLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRS----------------LIKKR 1065
Query: 2227 LFVPTPDAEEPQLP-DGTGREGPAAARGLANPEP-APEPKVLSSAASLPGSELPSSRPEG 2284
L+V P P LP GTGR ++ P+P PE + ++SA P L + R
Sbjct: 1066 LYVGEPH-RGPGLPHGGTGRS--LSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPR--- 1119
Query: 2285 SQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPF 2327
S+ +R ++ ++APG P +G P+
Sbjct: 1120 ---------LSLEGAARGAAEAKHKAPGSADYGFAPAAGRSPY 1153
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
Length = 1188
Score = 75.9 bits (185), Expect = 4e-13
Identities = 101/429 (23%), Positives = 147/429 (34%), Gaps = 57/429 (13%)
Query: 1892 GVWHQDGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLP 1951
G + QD +P PG + + P PG + +P P P P P P
Sbjct: 131 GQYGQDLLIPPPPPGPAPGPPQDISEP----PGGSPLPSPPSTAPPPPPLLLEP-----P 181
Query: 1952 SAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQ 2011
P P P A P + P P P + P P L FL P P +P PP
Sbjct: 182 PPPSMAPPPPPVLEALSPPHTLSSPSIPTPPD--FIPPAPPLAFLAPPPPPVPAPAPPAP 239
Query: 2012 ERRHLLQEARSPDPGIVPQEAPVG--NSLSELSEENFDGKFANLTPSRTVPDSEAPPGWD 2069
H + P G+ ++ V +E + + A S P+ E +
Sbjct: 240 ASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFP 299
Query: 2070 RADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWF-----FRWLPGK-----KKT 2119
R+ P P+ S P + +A +KE KK S F P +
Sbjct: 300 RSFKVPPPTPVRTSSIP-VQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAP 358
Query: 2120 EAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPV 2179
E P + + + Q + ++ +E PPP P P PPA P PP AP
Sbjct: 359 EPDCPGELKATAPASPRLGQ--SQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416
Query: 2180 NMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTP-DAEEPQ 2238
+++AA P+G ++ + +PA + P P P N P D +P
Sbjct: 417 LPCAQKAAHP---------PAGFTKTPKSSSPA--LKPKPNPPSPENTASSAPVDWRDPS 465
Query: 2239 LPD-----------GTGRE--------GPAAARGLANPEPAPEPKVLSSAASLPGSELPS 2279
+ G+ RE GP A + P + SLP + P
Sbjct: 466 QMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPP 525
Query: 2280 SRPEGSQGG 2288
PE S GG
Sbjct: 526 GVPEKSLGG 534
Score = 54.3 bits (129), Expect = 1e-06
Identities = 145/644 (22%), Positives = 210/644 (32%), Gaps = 109/644 (16%)
Query: 1 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 60
++PPP P MA PPP V A SP ++ + P P P
Sbjct: 178 LEPPP---PPSMAPPPPP-----VLEALSPPHTLSSPSIPTPPDFIPPAP---------- 219
Query: 61 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHP---GLLVPHTHARDSSQGPCEPLPGPLTQ- 116
PL + PPV PA S H L P + S T+
Sbjct: 220 -----PLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRA 274
Query: 117 --PRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPY-----LPHYIPGVD--- 166
PR+ A P AL P+ P RS +V P + ++P P G
Sbjct: 275 SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKA 334
Query: 167 ------PETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWG-PVQ 219
P + H P DR P + T ASP L Q Q + G P
Sbjct: 335 PSRLPLPPSFHIRPASQVYP--DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPP 392
Query: 220 GGPQPSGQHRSPCPEGPVPSG---VPCATSVPHFPTPSILHQGPGHEQHSPLVAPP---- 272
P P P P P+P +PCA H P P PP
Sbjct: 393 APPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPEN 452
Query: 273 --AALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPEL--RQNPGVKNEHR 328
++ P D RD + + LA R+ R ++H P + + G K
Sbjct: 453 TASSAPVDWRDPSQMEKLRNELAAYL---CGSRREDRFLSHRPGPTVAPQSKEGKKGPRL 509
Query: 329 PASALVNPLARGDSPENRTHHPLGAGAGSGCAPLE-ADSGASGALAMFFQGGETENEENL 387
P + L D+P LG GS E A S ++ Q T + +
Sbjct: 510 PEKETLLSLPAKDTPPGVPEKSLG---GSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQI 566
Query: 388 SSE-KAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTAST 446
+E +A LS A+ + + P +G P + G +C+ N A D +
Sbjct: 567 RNELEARLSSAAEKE---AKPSIGSLPPKPRLEGGRICE-------NGADDDKLSKPVAK 616
Query: 447 GVPDASGSQYENVENLEFVQNQEVLPSEPLN----LDPSSPSDQFRYGPLPGPAVPRHGA 502
+P Q+ +LP+ L L P+ P P PA+P
Sbjct: 617 NLPP---------------QSTTLLPTTSLQPKAMLGPAIPPK-----ATPEPAIPPKAT 656
Query: 503 VCHTGAPDATLHTVHPDSVSSS----YSSRSHGRLSGSARPQELVGTFIQQE-----VGK 553
+ P ATL P +S + S ++ +A + + E G+
Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716
Query: 554 PEDEASGSFFKQIDSSPVGGETDETTV-SQNYRGSVSQPSTPSP 596
PE AS + G ++ T + +Q R S + P SP
Sbjct: 717 PEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
Score = 50.1 bits (118), Expect = 3e-05
Identities = 121/479 (25%), Positives = 158/479 (32%), Gaps = 117/479 (24%)
Query: 1895 HQDGALPQQCPGTPSSEMEQLDRPGLSQPGA---LGIANPLLAVPAPSPEHSSPSVRLLP 1951
+ D A CPG + R G SQ A G P +P P+P P+ L P
Sbjct: 353 YPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPP 412
Query: 1952 SAPQTLPDG-----PLASPARVPMFPVP-LPPGPLEPGPGCVTPGPALGFLEPS------ 1999
+AP LP P A + P P L P P P P + + +PS
Sbjct: 413 AAPP-LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLR 471
Query: 2000 ---------------------GPGLPPGV------PPLQERRHLLQEARSPDPGIVPQEA 2032
GP + P P L E+ LL P VP+++
Sbjct: 472 NELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKS 531
Query: 2033 PVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPG 2092
G+SL+E PS T+P + P PT + E R
Sbjct: 532 LGGSSLTE----------TEAAPSLTLPSVDYIP-----QDSPTPSVRQIRNELEA-RLS 575
Query: 2093 QAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKA 2152
AA+KE K P G L G + E DDK L++P K
Sbjct: 576 SAAEKEAK-PSIGSLPPKPRLEGGRICENGADDDK---------------LSKP--VAKN 617
Query: 2153 PPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPA 2212
PP T++ T P A+ GP P +A + P T PA P
Sbjct: 618 LPPQSTTLLPTTSLQPKAMLGPAIPP-----------KATPEPAIPPKAT--LWPATPPK 664
Query: 2213 DFVAPLAPLPIPSNLFVPTPDAEEP-------QLPDGTGR------EGPA------AARG 2253
+ P PL S P P LP T + GPA A++
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
Query: 2254 LANPEPAPEPKVLSSAASLPGSELPSSR---PEGSQGGELSRC-----SSMSSLSREVS 2304
++ P A S A LP SS P+ S GG C SSLSREV+
Sbjct: 725 VSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVA 783
Score = 45.8 bits (107), Expect = 5e-04
Identities = 92/386 (23%), Positives = 129/386 (33%), Gaps = 98/386 (25%)
Query: 13 AGPPPAGNPRSVFWASSPYRRR---ANNNAAVAPTTCPLQPVTDP-FAFSRQALQST--- 65
A P PA P++ W ++P + A A + T PL+ + P A + L +T
Sbjct: 645 ATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQ 704
Query: 66 --------PLGSSSKSSPPVLQGPAPAGFSQHPG--LLVPHTHARDSSQGPCEPLPGP-- 113
P G K + + P+ A P +P AR S+ P + PG
Sbjct: 705 LMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGE 764
Query: 114 ---LTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPG------ 164
L +P H S S + A P + R GP EV+ P LP P
Sbjct: 765 VPCLYKPHCHQSSLSREV---AVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTD 821
Query: 165 ------VDPETSHGGHP----------------------HGNMPGLDRPLSRQNP--HDG 194
V E G P ++PG R S Q D
Sbjct: 822 ELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDS 881
Query: 195 VV----TP---AASPSLPQPG-------LQMPGQWGPVQG----GPQPSGQHR--SPCPE 234
+ TP P LP+ ++P +WGP G G + S +H P P+
Sbjct: 882 IFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQ 941
Query: 235 GPV----------PSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVS 284
PV P G P S P+PS + E + ++ PP +D
Sbjct: 942 APVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAP 1001
Query: 285 HLQSGSHLANNSDPE----STFRQNP 306
LQ +L S P S RQ P
Sbjct: 1002 ALQ---YLGRQSSPPRNNYSDLRQLP 1024
Score = 44.7 bits (104), Expect = 0.001
Identities = 220/1067 (20%), Positives = 331/1067 (31%), Gaps = 239/1067 (22%)
Query: 128 LTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRPLS 187
L P PPGP ++ S P LP P P P P P L
Sbjct: 138 LIPPPPPGPAPGPPQDI--SEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLE 195
Query: 188 RQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSV 247
+P + +SPS+P P +P P P +P P PVP+ P A +
Sbjct: 196 ALSPPHTL----SSPSIPTPPDFIP---------PAPPLAFLAP-PPPPVPAPAPPAPAS 241
Query: 248 PHFPTPSILHQGP-----------GHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNS 296
PH + G G + + +PP + P++ + GS L N
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRS-PAEPK--------GSALGPNP 292
Query: 297 DPESTFRQN-----PRIVNHWASPELRQNPGVKNEH----RPASALVNPLARGDSPENRT 347
+P TF ++ P V + P + E + S L P + P ++
Sbjct: 293 EPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQV 352
Query: 348 HHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSP 407
+ P A L+A + AS L G+++++ + E+AG A P
Sbjct: 353 Y-PDRAPEPDCPGELKATAPASPRL------GQSQSQ---ADERAGTPPPA--------P 394
Query: 408 GLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQN 467
L P P A L A P P + A T P +S + N
Sbjct: 395 PLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP--PAGFTKTPKSSSPALKPKPN------ 446
Query: 468 QEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATL-HTVHPDSVSSSYS 526
P P N S+P D + +C + D L H P S
Sbjct: 447 ----PPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE 502
Query: 527 SRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRG 586
+ RL L G PE GS + +++P
Sbjct: 503 GKKGPRLPEKETLLSLPAK--DTPPGVPEKSLGGSSLTETEAAP---------------- 544
Query: 587 SVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCR 646
S++ PS P Q S S +++ L E R + +K+ +
Sbjct: 545 SLTLPSVDYIP------QDSPTPSVRQIRNEL---------------EARLSSAAEKEAK 583
Query: 647 PAAALPDASP----GNLEQPPDNMETLCAPQVCPLPLNSTT-------EAVHML------ 689
P+ P G + + + + L P LP STT + ML
Sbjct: 584 PSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPP 643
Query: 690 ---PHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPA 746
P PP T++PA + + P+K S TT + P P +
Sbjct: 644 KATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTS 703
Query: 747 LYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQ 806
+ K P QP + A + + P Q+RG SE P
Sbjct: 704 QLMAEKDSGPAGQPEKPA-------SQEVSTPSQARGEGSPSEATRLP------------ 744
Query: 807 ASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGD 866
+ G S + PP S V H H+ + S A+V
Sbjct: 745 -TQGARSSAAFPPKTSPGGGEVPCLYKPH----------------CHQSSLSREVAVV-- 785
Query: 867 RPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPAN-LL 925
+ + A GG +G P + P G A S QP + LL
Sbjct: 786 ---MPTLARGGAAG------------------PGEPVEVKEPPGLPAKPPASAQPTDELL 824
Query: 926 VQPPSQPVPENLVP---------ESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVP 976
P + V E P +QK R G+AL G +S+
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAAL--------GRSSL------------ 864
Query: 977 DGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGP---- 1032
G+ +HS E + ++ S+ N V ++ P + GP
Sbjct: 865 PGSLRDHSHQAEASSDSIFH--SQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGR 922
Query: 1033 --GAPNLDRFYQQVTKDAQGQPGLERAQQELVP-----PQQQASPPQLPKAMFSELS--N 1083
L R + + Q ER +P P+ +SPP E N
Sbjct: 923 DAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFN 982
Query: 1084 PESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSG 1130
E +P + N + PA + Q PPR S L ++G G
Sbjct: 983 FEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPG 1029
Score = 42.7 bits (99), Expect = 0.004
Identities = 49/187 (26%), Positives = 59/187 (31%), Gaps = 11/187 (5%)
Query: 2152 APPPPPTSMPKTVQAAPPALPG----PPGAPVNMYSRRAAGTRARYVDVLNP--SGTQRS 2205
APPPPP P A P G PPG S A R +P S +
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 2206 EPALAPADFVAPLAPLPIPSNLFVPTPD-AEEPQLPDGTGREGPAAARGLANPEPAPEPK 2264
AL P P L P + VP P +P +E P G P+ P
Sbjct: 285 GSALGPN----PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPL 340
Query: 2265 VLSSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGA 2324
S P PE GEL + S + ++ G P A P A
Sbjct: 341 PPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPA 400
Query: 2325 MPFYNPA 2331
P PA
Sbjct: 401 PPLPPPA 407
Score = 35.8 bits (81), Expect = 0.51
Identities = 87/402 (21%), Positives = 145/402 (36%), Gaps = 54/402 (13%)
Query: 797 MGEEEALQSQASSGYASLLSSPPTESLQ--NPPVLIAQ--PDHSYNLAQPINFSVSLSNS 852
M +++ +Q S + ++ P+ SL NPP + Q P+ I + + N+
Sbjct: 1 MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT 60
Query: 853 -HEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSV------LSLSLPSSVAQS 905
E + +A RP ++ L EN L+ +PT SV ++ SS+
Sbjct: 61 VSESGTATLKARPRVRPLLTFLPLNAQ--ENHGLA-VPTPSVPDDFADKEVTGTSSLVNG 117
Query: 906 NFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVV 965
N S ++ Q L+ PP P P P+ + GS LP ++ ++
Sbjct: 118 NLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLL 177
Query: 966 LVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDS-LASQQSVA 1024
L PP ++ P + T S ++ P + P+ + LA
Sbjct: 178 LEPPPPPSMAPPPPPVLEALSPPHTLS------SPSIPTPPDFIPPAPPLAFLAPPPPPV 231
Query: 1025 SHPRQSGPGAPNL--DRFYQQ--VTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSE 1080
P P +P+ R + VTK + L Q E +ASPP+ P
Sbjct: 232 PAPAPPAPASPHTVGTRLFPPGGVTK-WKSDVALNGRQAEAT----RASPPRSPAEPKGS 286
Query: 1081 LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPW 1140
P P L + + PP P ++SS+ + + Q A E+
Sbjct: 287 ALGPNPEP-------------HLTFPRSFKVPPPTPVRTSSIPVQEA---QEAPRKEEGA 330
Query: 1141 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPG 1182
+ P+ P PP ++ RP Y + P P PG
Sbjct: 331 TKKAPSRLPLPPS------FHIRPASQVYPDR--APEPDCPG 364
Score = 35.4 bits (80), Expect = 0.67
Identities = 68/283 (24%), Positives = 92/283 (32%), Gaps = 78/283 (27%)
Query: 2058 TVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKK 2117
T P+ +AP W+R AP G K P
Sbjct: 936 TKPEPQAPVAWERV-------------APSNLPQGHPLPKSFSSP--------------- 967
Query: 2118 KTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPP-------- 2169
P NK +E+ N V PE PP P Q++PP
Sbjct: 968 ------PSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLR 1021
Query: 2170 ALP--GPPGAPVNMYSRRAAGTRARYVDVLNP-SGTQRSEPALAPADFVAPLAPLPIPSN 2226
LP GP P +SR AG R L SG RS I
Sbjct: 1022 QLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRS----------------LIKKR 1065
Query: 2227 LFVPTPDAEEPQLP-DGTGREGPAAARGLANPEP-APEPKVLSSAASLPGSELPSSRPEG 2284
L+V P P LP GTGR ++ P+P PE + ++SA P L + R
Sbjct: 1066 LYVGEPH-RGPGLPHGGTGRS--LSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPR--- 1119
Query: 2285 SQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPF 2327
S+ +R ++ ++APG P +G P+
Sbjct: 1120 ---------LSLEGAARGAAEAKHKAPGSADYGFAPAAGRSPY 1153
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 72.0 bits (175), Expect = 6e-12
Identities = 111/433 (25%), Positives = 147/433 (33%), Gaps = 46/433 (10%)
Query: 1919 GLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPG 1978
GL +P + +++ A P SP S PS R P AP A P++ P P G
Sbjct: 224 GLQRPASRSLSSS--ATPLSSPARSGPSARGTPRAP--------AHPSQ------PKPKG 267
Query: 1979 PLEPGPGCVTP-----GPALGFLEPSGPGLP-PGVPPLQERRHLLQEARSPDPGIVPQEA 2032
P VTP PALG L S P P PP LQ SP P P +A
Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP-PATPPSQA 326
Query: 2033 PVGNSLSELSEENFDGKFANLTPSRTVPDSEAP----PGWDRADSGPTQPPLSLSPAPET 2088
L + L+P T P P P S P PPLS P
Sbjct: 327 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 386
Query: 2089 KRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEE 2148
+ P A + P P +A + + +
Sbjct: 387 QAPNALAVHLLQAPFSP--------PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 438
Query: 2149 EKKAPPPPPTSMPKTVQAAPPALPGPPGA--PVNMYSRRAAGTRARYVDVLNP-SGTQRS 2205
+ PP PP S P + A PP PP A P+ + A L S
Sbjct: 439 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 498
Query: 2206 EPALAPADFVA--PLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEP 2263
P AP A P++PL P P A Q+P + P P P P+
Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP-SPPASPTLQAPRRPPTPGPDT 557
Query: 2264 KVLSSAASL---PGSELPSSRPEGS--QGGELSRCSSMSSLSREVSQHFNQAPGDLPAAG 2318
V +L PG P SR S G +L+ SS ++ + E + ++ P AA
Sbjct: 558 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 617
Query: 2319 GPPSGAMPFYNPA 2331
PP + +PA
Sbjct: 618 PPPDAELAACHPA 630
Score = 63.2 bits (152), Expect = 3e-09
Identities = 86/286 (30%), Positives = 108/286 (37%), Gaps = 50/286 (17%)
Query: 5 PQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQS 64
P+ PS PP G +SV AS ++ P+ + + R A +S
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASE--------HSTTEPSPAARRRPSAGGGLQRPASRS 232
Query: 65 -----TPLGSSSKSSPPVLQGP-APAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPR 118
TPL S ++S P P APA HP P +G P +T PR
Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAPA----HPSQPKP--------KGLQALRPPQVTPPR 280
Query: 119 AHASPFSGAL--TPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHP- 175
A+P G L +P A P P SA PS+ P +QTLP P P T+ G P
Sbjct: 281 KDAAPALGPLSSSPLATPSP----SAPPSPSAPPSLQTLPSPPATPP--SQATTSLGSPT 334
Query: 176 ----HGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSP 231
H +P PLS P A P+L P LQ P P P +P
Sbjct: 335 LQATHSFLP--SPPLSPL----ATPPPQAPPALALPPLQAP----PSPPASPPLSPLATP 384
Query: 232 CPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPS 277
P+ P V P P PS Q P SP V+P A PS
Sbjct: 385 SPQAPNALAVH-LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429
Score = 58.5 bits (140), Expect = 7e-08
Identities = 100/372 (26%), Positives = 133/372 (35%), Gaps = 31/372 (8%)
Query: 1966 ARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDP 2025
AR P P PPG P P VTP AL L +G G PL ER + A P+
Sbjct: 19 ARAPGLLTPRPPGSPRPPPP-VTPA-ALRVLGAAGA---VGRKPLAERAGGIGGATIPES 73
Query: 2026 GIVPQEAPVGNSLSELSEENFDGKFANLTPSR-TVPDSEAPPGWDRADSGPTQP-PLSLS 2083
P+ P S S G+ P++ T P + PG RA SG T+P PL
Sbjct: 74 A--PRAGPTRTSRPPAS-----GRGERAPPAKNTSPGPVSSPG--RA-SGTTRPGPLGQK 123
Query: 2084 PAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNL 2143
+ A K T+ PK+ ++ T P + ++ + +
Sbjct: 124 GLRISAEETVARGKATEAPKRSALS----AGARRDTSGPTPGTPSPAMA-RRSRAAGTEV 178
Query: 2144 NEPEEEKKAPPPPPTSMP-KTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGT 2202
P A P PPT P K+V +A P G + L+ S T
Sbjct: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 238
Query: 2203 QRSEPALA-PADFVAPLAPL----PIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANP 2257
S PA + P+ P AP P P L P P D GP ++ LA P
Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 298
Query: 2258 EPA--PEPKVLSSAASLPG-SELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDL 2314
P+ P P S +LP P S+ S G + + S +S P
Sbjct: 299 SPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358
Query: 2315 PAAGGPPSGAMP 2326
PA PP A P
Sbjct: 359 PALALPPLQAPP 370
Score = 57.0 bits (136), Expect = 2e-07
Identities = 111/448 (24%), Positives = 146/448 (32%), Gaps = 69/448 (15%)
Query: 3 PPPQTVPSGMAGP-------PPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQ--PVTD 53
P P PS A P PPA P + +A ++ +P PL P
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357
Query: 54 PFAFSRQALQSTPLGSSSKSSPPV--LQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLP 111
P A + LQ+ P S +SPP+ L P+P Q P L H S P P+
Sbjct: 358 PPALALPPLQAPP---SPPASPPLSPLATPSP----QAPNALAVHLLQAPFSPPPSPPVQ 410
Query: 112 GPLTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSH 171
P + P ASP ++PSA P + S P P + P P P P
Sbjct: 411 APFSPP---ASP---PVSPSATPPSQAPPSLAAPPLQVPP--SPPASPPMSPSATPP--- 459
Query: 172 GGHPHGNMPGLDRPLSRQNPHDGVVTPAASP---SLPQPGLQMPGQWGPVQGGPQPSGQH 228
P P PL P A+P +LP P PGQ P
Sbjct: 460 ---PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516
Query: 229 RSPCPEGP---------VPSGVPCATSV-----PHFPTPSILHQGPGHEQHSPLVAPPAA 274
+P P+ P VP P + ++ P P P GP L P
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP----RLTLALAPGP 572
Query: 275 LPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALV 334
P R S L SG LA +S ++ + R + +P E A
Sbjct: 573 PPPPSRSPSSTL-SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE----LAAC 627
Query: 335 NPLARGDSPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGL 394
+P A P GA P A G ++ ETE E+ + L
Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY----ETEGPESATPAPGAL 683
Query: 395 SGQADFDDFCSSPGLGRPPAPTHVGAGS 422
D SPG A GAG+
Sbjct: 684 -------DPGPSPGTSGGKAAAGAGAGA 704
Score = 56.2 bits (134), Expect = 4e-07
Identities = 139/620 (22%), Positives = 198/620 (31%), Gaps = 150/620 (24%)
Query: 567 DSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEA 626
+S+P G T + + RG + P+ + P P +S + + +G K
Sbjct: 72 ESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPV----SSPGRASGTTRPGPLGQKGLRI 127
Query: 627 DRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAV 686
V + T ++ A A D S P P + + A+
Sbjct: 128 SAEETVARGKATEAPKRSALSAGARRDTSG-------------------PTP-GTPSPAM 167
Query: 687 HMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPAT------TLWAQSELPDFGGNVLL 740
A + PAP RP T+GP K S A+ A P GG L
Sbjct: 168 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG-LQ 226
Query: 741 APAAPALYVCAKP-QPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGE 799
PA+ +L A P P P + + +PS P +G PP+
Sbjct: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP---KGLQALRPPQVTPPRKDA 283
Query: 800 EEALQSQASSGYAS-LLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQS 858
AL +SS A+ S+PP+ S PP L P A P
Sbjct: 284 APALGPLSSSPLATPSPSAPPSPSA--PPSLQTLPSPP---ATP---------------- 322
Query: 859 WREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVS 918
P+ ++ +LG + + T S +P+ + L+ P PQ A +
Sbjct: 323 ---------PSQATTSLGSPTLQATH-SFLPSPPLSPLATPP-------PQAPPALALPP 365
Query: 919 NQPANLLVQPPSQPVPENLVPESQKDRKAGSAL------PGFANSPAGSTSVVLVPPAHG 972
L PPS P L P + +A +AL F+ P+ PPA
Sbjct: 366 ------LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA-- 417
Query: 973 TLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGP 1032
PV +PS + + S+A+ P Q P
Sbjct: 418 ------------------------------SPPV---SPSATPPSQAPPSLAAPPLQVPP 444
Query: 1033 GAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQ 1092
P T Q P L +L P QA P + + S P S P Q
Sbjct: 445 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504
Query: 1093 AQNSAQSPASLVLVDAGQ----------QLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQ 1142
SA P S + Q Q+PP PP S ++ P P P
Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ----------APRRPPTPG 554
Query: 1143 P---------VPALAPGPPP 1153
P ALAPGPPP
Sbjct: 555 PDTSVSGPRLTLALAPGPPP 574
Score = 54.7 bits (130), Expect = 1e-06
Identities = 116/459 (25%), Positives = 150/459 (32%), Gaps = 104/459 (22%)
Query: 1901 PQQCPGTP--SSEMEQLDRPGLSQPGALGI--------ANPLLAVPAPSPEHSSPSVRLL 1950
P Q P +P S + L P P AL + P V AP +SP V
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424
Query: 1951 PSAPQTLPDGPLASPARVPMFPVPLPP-GPLEPGPGCVTPGPALGFLEPSGPGLPPGVPP 2009
+ P P A P +VP P PP P P P A L+ + P PP PP
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP--PPQAPP 482
Query: 2010 LQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWD 2069
L +A P P +AP S S ++P T P +APP
Sbjct: 483 ALATPPL--QALPSPPASFPGQAPFSPSAS-----------LPMSPLAT-PPPQAPPVL- 527
Query: 2070 RADSGPTQPPLSLSPAPETKRPGQAAKK-ETKEPKKGESWFFRWLPGKKKTEAYLPDDKN 2128
P L + P+P QA ++ T P S G + T A P
Sbjct: 528 ------AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS-------GPRLTLALAP---- 570
Query: 2129 KSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAG 2188
PPPPP+ P + + P L G + S +
Sbjct: 571 -----------------------GPPPPPSRSPSSTLSGPD-LAG------HSSSATSTP 600
Query: 2189 TRARYVDVLNPSGTQRSEPALAPADFVAPLA--PLPIPSNLF-------VPTPDAEEPQL 2239
R D G S P A P A P P F +P P A P
Sbjct: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 660
Query: 2240 PDG-------TGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSSRPEGSQGGELSR 2292
DG G E A G +P P+P AA+ G+ S P+ ++ GEL
Sbjct: 661 ADGLCTIYETEGPESATPAPGALDPGPSPGTSG-GKAAAGAGAGASSRSPKQARLGEL-- 717
Query: 2293 CSSMSSLSREVSQH-------FNQAPGDLPAAGGPPSGA 2324
+ +L V QH A G +GG P GA
Sbjct: 718 --PLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGA 754
Score = 50.4 bits (119), Expect = 2e-05
Identities = 58/241 (24%), Positives = 83/241 (34%), Gaps = 23/241 (9%)
Query: 588 VSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRP 647
+S +TPSP P + + F P S V PF + V P
Sbjct: 378 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA-PFSPPASPPVS-------------P 423
Query: 648 AAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKR 707
+A P +P +L PP ++ +P P S T P APPL P P+
Sbjct: 424 SATPPSQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481
Query: 708 PSARTQGPVKCESPATTLWAQSELPDFGG---NVLLAPAAPALYVCAKPQPPVVQPPEEA 764
P+ T SP + Q+ + L P A V A P V P +
Sbjct: 482 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 541
Query: 765 MSGQQSRNPSSAAPVQSRGG----IGASENLENPPKMGEEEALQSQASSGYASLLSSPPT 820
+ Q R P + P S G + + PP L +G++S +S P
Sbjct: 542 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 601
Query: 821 E 821
E
Sbjct: 602 E 602
Score = 48.5 bits (114), Expect = 8e-05
Identities = 85/378 (22%), Positives = 129/378 (34%), Gaps = 69/378 (18%)
Query: 894 LSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPG 953
L +S +VA+ + S + + + P P P +++ R AG+ +
Sbjct: 125 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM----ARRSRAAGTEV-- 178
Query: 954 FANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSH 1013
P + S PP G + + HS+ + + L+ P
Sbjct: 179 --GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA------- 229
Query: 1014 SDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQP-GLERAQQELVPPQQQASPPQ 1072
S SL+S + S P +SGP A R +Q +P GL+ + V P ++ + P
Sbjct: 230 SRSLSSSATPLSSPARSGPSARGTPR---APAHPSQPKPKGLQALRPPQVTPPRKDAAPA 286
Query: 1073 LPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQA 1132
L S L+ P A S +P SL + + PP P S + + + S + QA
Sbjct: 287 LGPLSSSPLATPSP-----SAPPSPSAPPSLQTLPS----PPATPPSQATTSLGSPTLQA 337
Query: 1133 A---------VPSEQPWPQPVPALA-------PGPP---------------PQDLAAYYY 1161
P P PQ PALA P PP P LA +
Sbjct: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397
Query: 1162 YRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERP 1221
P P P+ P P + + P P A + A P P
Sbjct: 398 QAPFSPPPSPPVQAPFSP-PASPPV---------SPSATPPSQAPPSLAAPPLQVPPSPP 447
Query: 1222 SSRASHSSERPPPRQGYP 1239
+S S PPP+ P
Sbjct: 448 ASPPMSPSATPPPQAPPP 465
Score = 44.7 bits (104), Expect = 0.001
Identities = 112/461 (24%), Positives = 141/461 (30%), Gaps = 126/461 (27%)
Query: 1905 PGTPSSEMEQLDRP-----GLSQPGALGIANPLLAVPAPS----PEHS----SPSVRLLP 1951
PGTPS M + R GL +P P P S EHS SP+ R P
Sbjct: 160 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 219
Query: 1952 SAPQTLPDGPLASPARVPMFPVPLP-PGPLEPGPGCVTPGPALGFLEPSGPGLPPG-VPP 2009
SA G L PA + P P GP S G P P
Sbjct: 220 SA-----GGGLQRPASRSLSSSATPLSSPARSGP--------------SARGTPRAPAHP 260
Query: 2010 LQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWD 2069
Q + LQ R P + P +L LS TPS + P S + P
Sbjct: 261 SQPKPKGLQALRPPQ--VTPPRKDAAPALGPLSSSPL------ATPSPSAPPSPSAP--- 309
Query: 2070 RADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNK 2129
P L P+P P QA P + T ++LP
Sbjct: 310 --------PSLQTLPSPPATPPSQATTSLGS-------------PTLQATHSFLPSPPLS 348
Query: 2130 SIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAP--VNMYSRRAA 2187
+ PPP + P A P PP +P + +
Sbjct: 349 PLA---------------------TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 387
Query: 2188 GTRARYVDVLN---------------------PSGTQRSEPALAPADFVAPLAPLPIPSN 2226
A V +L P + P+ AP AP PL +P
Sbjct: 388 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP--PLQVP-- 443
Query: 2227 LFVPTPDAEEPQLPDGTGREGPAAARGLANPE---PAPEPKVLSSAASLPGSELPSSRPE 2283
P+P A P P T P A LA P P P+ + A+ P LPS P
Sbjct: 444 ---PSPPASPPMSPSAT--PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPS--PP 496
Query: 2284 GSQGGELSRCSSMSSLSREVSQHFNQAPGDL--PAAGGPPS 2322
S G+ S S ++ QAP L P PPS
Sbjct: 497 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 537
Score = 32.0 bits (71), Expect = 7.4
Identities = 46/155 (29%), Positives = 59/155 (38%), Gaps = 26/155 (16%)
Query: 1899 ALPQQCPGTPSSE--MEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQT 1956
+ P Q P +PS+ M L P P L A PLL VP PSP +SP+++ P
Sbjct: 498 SFPGQAPFSPSASLPMSPLATPPPQAPPVL--AAPLLQVP-PSPP-ASPTLQAPRRPPTP 553
Query: 1957 LPD--------------GPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGP- 2001
PD GP P+R P + P TP G+ SGP
Sbjct: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY--DSGPE 611
Query: 2002 -GLPPGVPPLQERR--HLLQEARSPDPGIVPQEAP 2033
G PP E H +R P P + + AP
Sbjct: 612 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 646
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 71.2 bits (173), Expect = 1e-11
Identities = 115/449 (25%), Positives = 153/449 (34%), Gaps = 70/449 (15%)
Query: 1905 PGTPSSEMEQLDRPGLSQP---GALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGP 1961
P P + Q RP P A PL + P +P SPS L AP TLP P
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP---SPSAALQSQAPPTLPATP 325
Query: 1962 LASPARVPMF-PVPL-PPGPLEPGPGCVTPGPALGFLEPSGPGLPP-------GVPPLQE 2012
+S + P+PL PP P P P+L L PS P PP G P LQ
Sbjct: 326 HSSSLTCQLATPLPLAPPSPSAP--------PSLQTL-PSPPATPPSQATTSLGSPTLQA 376
Query: 2013 RRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRAD 2072
L P P + P P + P+ +P +APP
Sbjct: 377 THSFL-----PSPPLSPLATPPPQA----------------PPALALPPLQAPP------ 409
Query: 2073 SGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIV 2132
S P PPLS P + P A + P P +A + +
Sbjct: 410 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSP--------PPSPPVQAPFSPPASPPVS 461
Query: 2133 WDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGA--PVNMYSRRAAGTR 2190
+ + PP PP S P + A PP PP A P+ +
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521
Query: 2191 ARYVDVLNP-SGTQRSEPALAPADFVA--PLAPLPIPSNLFVPTPDAEEPQLPDGTGREG 2247
A L S P AP A P++PL P P A Q+P +
Sbjct: 522 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP-SPPAS 580
Query: 2248 PAAARGLANPEPAPEPKVLSSAASL---PGSELPSSRPEGS--QGGELSRCSSMSSLSRE 2302
P P P P+ V +L PG P SR S G +L+ SS ++ + E
Sbjct: 581 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 640
Query: 2303 VSQHFNQAPGDLPAAGGPPSGAMPFYNPA 2331
+ ++ P AA PP + +PA
Sbjct: 641 ELRGYDSGPEGGAAASPPPDAELAACHPA 669
Score = 67.8 bits (164), Expect = 1e-10
Identities = 122/481 (25%), Positives = 161/481 (33%), Gaps = 88/481 (18%)
Query: 702 PAPEKRPSARTQGPVKCESPAT------TLWAQSELPDFGGNVLLAPAAPALYVCAKP-Q 754
PAP RP T+GP K S A+ A P GG L PA+ +L A P
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG-LQRPASRSLSSSATPLS 250
Query: 755 PPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASL 814
P P + + +PS P +G PP+ AL +SS A+
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKP---KGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 815 LSSPPTESLQNPPVLIAQPDHS---YNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVS 871
S +S Q PP L A P S LA P+ + ++ Q+ + PA
Sbjct: 308 SPSAALQS-QAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT-----LPSPPATP 361
Query: 872 SWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQ 931
P+ + SL P+ A +F + + P + L PP Q
Sbjct: 362 -----------------PSQATTSLGSPTLQATHSF---------LPSPPLSPLATPPPQ 395
Query: 932 PVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTY 991
P +P Q A P SP S P A L +A S
Sbjct: 396 APPALALPPLQ-------APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 448
Query: 992 GALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQ 1051
A S PV +PS + + S+A+ P Q P P T Q
Sbjct: 449 QA---PFSPPASPPV---SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502
Query: 1052 PGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQ- 1110
P L +L P QA P + + S P S P Q SA P S + Q
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 562
Query: 1111 ---------QLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQP---------VPALAPGPP 1152
Q+PP PP S ++ P P P P ALAPGPP
Sbjct: 563 PPVLAAPLLQVPPSPPASPTLQ----------APRRPPTPGPDTSVSGPRLTLALAPGPP 612
Query: 1153 P 1153
P
Sbjct: 613 P 613
Score = 57.4 bits (137), Expect = 2e-07
Identities = 130/520 (25%), Positives = 175/520 (33%), Gaps = 86/520 (16%)
Query: 1841 SPVLISQLVQMASQLRLFDPQLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGAL 1900
+P S Q+A+ L L P P ++L +P Q H
Sbjct: 324 TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 383
Query: 1901 PQQCP--GTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPE-HSSPSVRLL--PSAPQ 1955
P P P L P L P + + PL + PSP+ ++ +V LL P +P
Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443
Query: 1956 TLP--DGPLASPARVPMFPVPLPPGPLEPG----PGCVTPG-PALGFLEPSGPGLPPGVP 2008
P P + PA P+ P PP P P V P PA + PS P P
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 503
Query: 2009 PLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGW 2068
PL LQ A+ P P P A +F G+ A +PS ++P S
Sbjct: 504 PLAAPP--LQLAK-PPPQAPPALATPPLQALPSPPASFPGQ-APFSPSASLPMSPLATPP 559
Query: 2069 DRADSGPTQPPLSLSPAPETKRPGQAAKK-ETKEPKKGESWFFRWLPGKKKTEAYLPDDK 2127
+A P L + P+P QA ++ T P S G + T A P
Sbjct: 560 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS-------GPRLTLALAP--- 609
Query: 2128 NKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAA 2187
PPPPP+ P + + P L G + S +
Sbjct: 610 ------------------------GPPPPPSRSPSSTLSGPD-LAG------HSSSATST 638
Query: 2188 GTRARYVDVLNPSGTQRSEPALAPADFVAPLA--PLPIPSNLF-------VPTPDAEEPQ 2238
R D G S P A P A P P F +P P A P
Sbjct: 639 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 698
Query: 2239 LPDG-------TGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSSRPEGSQGGELS 2291
DG G E A G +P P+P AA+ G+ S P+ ++ GEL
Sbjct: 699 SADGLCTIYETEGPESATPAPGALDPGPSPGTSG-GKAAAGAGAGASSRSPKQARLGEL- 756
Query: 2292 RCSSMSSLSREVSQH-------FNQAPGDLPAAGGPPSGA 2324
+ +L V QH A G +GG P GA
Sbjct: 757 ---PLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGA 793
Score = 56.6 bits (135), Expect = 3e-07
Identities = 110/441 (24%), Positives = 146/441 (33%), Gaps = 67/441 (15%)
Query: 3 PPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQ--PVTDPFAFSRQ 60
P QT+PS PPA P + +A ++ +P PL P P A +
Sbjct: 349 PSLQTLPS-----PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403
Query: 61 ALQSTPLGSSSKSSPPV--LQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPR 118
LQ+ P S +SPP+ L P+P Q P L H S P P+ P + P
Sbjct: 404 PLQAPP---SPPASPPLSPLATPSP----QAPNALAVHLLQAPFSPPPSPPVQAPFSPP- 455
Query: 119 AHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGN 178
ASP ++PSA P + S P P + P P P P P
Sbjct: 456 --ASP---PVSPSATPPSQAPPSLAAPPLQVPP--SPPASPPMSPSATPP------PQAP 502
Query: 179 MPGLDRPLSRQNPHDGVVTPAASP---SLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEG 235
P PL P A+P +LP P PGQ P +P P+
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 562
Query: 236 P---------VPSGVPCATSV-----PHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRD 281
P VP P + ++ P P P GP L P P R
Sbjct: 563 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP----RLTLALAPGPPPPPSRS 618
Query: 282 EVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGD 341
S L SG LA +S ++ + R + +P E A +P A
Sbjct: 619 PSSTL-SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE----LAACHPAAWSR 673
Query: 342 SPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFD 401
P GA P A G ++ ETE E+ + L
Sbjct: 674 GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY----ETEGPESATPAPGAL------- 722
Query: 402 DFCSSPGLGRPPAPTHVGAGS 422
D SPG A GAG+
Sbjct: 723 DPGPSPGTSGGKAAAGAGAGA 743
Score = 55.1 bits (131), Expect = 8e-07
Identities = 126/499 (25%), Positives = 175/499 (35%), Gaps = 83/499 (16%)
Query: 351 LGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLG 410
LGA G PL +G G G T E S+ +AG + A S
Sbjct: 47 LGAAGAVGRKPLAERAGGIG--------GATIPE---SAPRAGPTRSAGTS---SRNPAS 92
Query: 411 RPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEV 470
RPPA + PGP + G + T P G + + E V +
Sbjct: 93 RPPASGRGERAPPAKNTSPGPVSSP-----GRASGTTRPGPLGQKGLRISAEETVARGKA 147
Query: 471 LPSEPLNLDPSSPSDQFRYGPLPG---PAVPRHGAVCHTG------APDATLH--TVHPD 519
+ P S+ + + GP PG PA+ R T AP A T P
Sbjct: 148 TEA-PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206
Query: 520 SVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETT 579
SS S S S +AR + G +Q+ + ++ S P
Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP--------- 257
Query: 580 VSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETC 639
+ RG+ P+ PS PKP G+ + P + V P D A +G + +
Sbjct: 258 ---SARGTPRAPAHPSQPKPKGL------QALRPPQ-----VTPPRKDAAPALGPLSSSP 303
Query: 640 VRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDT 699
+ P+AAL +P L P + C PLPL P APP
Sbjct: 304 LATPS--PSAALQSQAPPTLPATPHSSSLTC-QLATPLPLAP--------PSPSAPPSLQ 352
Query: 700 VYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAP---AAPALYVCAKPQPP 756
P+P P +Q SP T S LP + L P A PAL + PP
Sbjct: 353 TLPSPPATPP--SQATTSLGSP-TLQATHSFLPSPPLSPLATPPPQAPPALAL-----PP 404
Query: 757 VVQPPEEAMSGQQS--RNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASL 814
+ PP S S PS AP + + + +PP +A S +S S
Sbjct: 405 LQAPPSPPASPPLSPLATPSPQAP--NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 462
Query: 815 LSSPPTESLQNPPVLIAQP 833
++PP+ Q PP L A P
Sbjct: 463 SATPPS---QAPPSLAAPP 478
Score = 52.0 bits (123), Expect = 7e-06
Identities = 101/391 (25%), Positives = 141/391 (36%), Gaps = 46/391 (11%)
Query: 1966 ARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPD- 2024
AR P P PPG P P VTP AL L +G G PL ER + A P+
Sbjct: 19 ARAPGLLTPRPPGSPRPPPP-VTPA-ALRVLGAAGA---VGRKPLAERAGGIGGATIPES 73
Query: 2025 -PGIVPQEAPVGNSLSELSEENFDGKFANLTPSR-TVPDSEAPPGWDRADSGPTQP-PLS 2081
P P + +S + S G+ P++ T P + PG RA SG T+P PL
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG--RA-SGTTRPGPLG 130
Query: 2082 LSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWV 2141
+ A K T+ PK+ ++ T P + ++ +
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALS----AGARRDTSGPTPGTPSPAMA-RRSRAAGT 185
Query: 2142 NLNEPEEEKKAPPPPPTSMP-KTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPS 2200
+ P A P PPT P K+V +A P G + L+ S
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 2201 GTQRSEPALA-PADFVAPLAPL----PIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLA 2255
T S PA + P+ P AP P P L P P D GP ++ LA
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
Query: 2256 NPEPAPEPKVLSSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLP 2315
P P +A+L P+ L SSL+ +++ AP P
Sbjct: 306 TPSP---------SAALQSQAPPT----------LPATPHSSSLTCQLATPLPLAP---P 343
Query: 2316 AAGGPPS-GAMPFYNPAQLAQACATSGSSRL 2345
+ PPS +P +QA + GS L
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTL 374
Score = 52.0 bits (123), Expect = 7e-06
Identities = 84/312 (26%), Positives = 108/312 (34%), Gaps = 72/312 (23%)
Query: 5 PQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQS 64
P+ PS PP G +SV AS ++ P+ + + R A +S
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASE--------HSTTEPSPAARRRPSAGGGLQRPASRS 241
Query: 65 -----TPLGSSSKSSPPVLQGP-APAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPR 118
TPL S ++S P P APA HP P +G P +T PR
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPA----HPSQPKP--------KGLQALRPPQVTPPR 289
Query: 119 AHASPFSGAL--TPSAPPGPEMNRSAEV--------------------------GPSSEP 150
A+P G L +P A P P ++ PS+ P
Sbjct: 290 KDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP 349
Query: 151 EVQTLPYLPHYIPGVDPETSHGGHP-----HGNMPGLDRPLSRQNPHDGVVTPAASPSLP 205
+QTLP P P T+ G P H +P PLS P A P+L
Sbjct: 350 SLQTLPSPPATPP--SQATTSLGSPTLQATHSFLP--SPPLSPL----ATPPPQAPPALA 401
Query: 206 QPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQH 265
P LQ P P P +P P+ P V P P PS Q P
Sbjct: 402 LPPLQAP----PSPPASPPLSPLATPSPQAPNALAVH-LLQAPFSPPPSPPVQAPFSPPA 456
Query: 266 SPLVAPPAALPS 277
SP V+P A PS
Sbjct: 457 SPPVSPSATPPS 468
Score = 50.4 bits (119), Expect = 2e-05
Identities = 104/389 (26%), Positives = 131/389 (33%), Gaps = 87/389 (22%)
Query: 895 SLSLPSSVAQSNFPQGSGASEM-VSNQPANLLVQPPSQPVPENLV----PESQKDRK-AG 948
S SL SS + P SG S PA+ PSQP P+ L P+ RK A
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAH-----PSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 949 SALPGFANSPAG--STSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPV 1006
AL ++SP S S L A TL HSS +L+ L P+
Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPA----TPHSS-----------SLTCQLATPL 338
Query: 1007 NVYNPSHS-----DSLASQQSVASHPRQSGPGAPNLDRFYQQV---------TKDAQGQP 1052
+ PS S +L S + + G+P L + + T Q P
Sbjct: 339 PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 398
Query: 1053 GLERAQQELVPPQQQASPP---------QLPKAMFSEL-----------------SNPES 1086
L + PP ASPP Q P A+ L S P S
Sbjct: 399 ALALPPLQ-APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457
Query: 1087 LPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPA 1146
P A +Q+P SL Q+PP PP S +S A P + P P P
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPL--QVPPSPPASPPMS------PSATPPPQAPPPLAAPP 509
Query: 1147 L-APGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSL-YEPRYRPYDG 1204
L PPPQ P A P +LP PP + SL P P
Sbjct: 510 LQLAKPPPQ--------APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 561
Query: 1205 AASAYAQNYRYPEPERPSSRASHSSERPP 1233
A A P P+S + RPP
Sbjct: 562 APPVLAAPLLQVPPSPPASPTLQAPRRPP 590
Score = 50.4 bits (119), Expect = 2e-05
Identities = 58/241 (24%), Positives = 83/241 (34%), Gaps = 23/241 (9%)
Query: 588 VSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRP 647
+S +TPSP P + + F P S V PF + V P
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA-PFSPPASPPVS-------------P 462
Query: 648 AAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKR 707
+A P +P +L PP ++ +P P S T P APPL P P+
Sbjct: 463 SATPPSQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 520
Query: 708 PSARTQGPVKCESPATTLWAQSELPDFGG---NVLLAPAAPALYVCAKPQPPVVQPPEEA 764
P+ T SP + Q+ + L P A V A P V P +
Sbjct: 521 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 580
Query: 765 MSGQQSRNPSSAAPVQSRGG----IGASENLENPPKMGEEEALQSQASSGYASLLSSPPT 820
+ Q R P + P S G + + PP L +G++S +S P
Sbjct: 581 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 640
Query: 821 E 821
E
Sbjct: 641 E 641
Score = 46.6 bits (109), Expect = 3e-04
Identities = 81/354 (22%), Positives = 124/354 (35%), Gaps = 57/354 (16%)
Query: 894 LSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPG 953
L +S +VA+ + S + + + P P P +++ R AG+ +
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM----ARRSRAAGTEV-- 187
Query: 954 FANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSH 1013
P + S PP G + + HS+ + + L+ P
Sbjct: 188 --GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA------- 238
Query: 1014 SDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQP-GLERAQQELVPPQQQASPPQ 1072
S SL+S + S P +SGP A R +Q +P GL+ + V P ++ + P
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPR---APAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
Query: 1073 LPKAMFSELSNPE---SLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSV-SLVSSG 1128
L S L+ P +L +Q A +S + LP PP S+ SL +
Sbjct: 296 LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP 355
Query: 1129 SGQAAVPSE------QPWPQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPG 1182
S A PS+ P Q + P PP LA P P P
Sbjct: 356 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT-----------------PPPQAPP 398
Query: 1183 AASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERP--PP 1234
A +L P P AS P P+ P++ A H + P PP
Sbjct: 399 ALAL---------PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443
Score = 32.7 bits (73), Expect = 4.3
Identities = 163/771 (21%), Positives = 230/771 (29%), Gaps = 171/771 (22%)
Query: 90 PGLLVPHTHARDSSQGPCEPLPGPLTQPRA-----------------HASPFSGALTPSA 132
PGLL P P P P P P A A GA P +
Sbjct: 22 PGLLTPRP--------PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 133 PPGPEMNRSAEVG---PSSEPEV----QTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRP 185
P RSA P+S P + P + PG P +S G PG P
Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG--PVSSPGRASGTTRPG---P 128
Query: 186 LSRQNPH--------DGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPV 237
L ++ G T A S G + GP G P P+ RS V
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS-GPTPGTPSPAMARRSRAAGTEV 187
Query: 238 PSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAA--LPSDGRD-----EVSHLQSGS 290
P ++ P PT +HS PAA PS G S S +
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 291 HLANNSDPESTFRQNPRIVNHWASPELR-----QNPGVKNEHRPASALVNPLARGDSPEN 345
L++ + + R PR H + P+ + + P V + A+ + PL+
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS----- 302
Query: 346 RTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCS 405
PL + S +A T + +L+ + A
Sbjct: 303 ----PLATPSPSAALQSQAPPTLPA----------TPHSSSLTCQLA------------- 335
Query: 406 SPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFV 465
+P PP+P+ A Q L P+ + T S G P + F+
Sbjct: 336 TPLPLAPPSPS---APPSLQTLPSPPATPPS----QATTSLGSPTLQATH-------SFL 381
Query: 466 QNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSY 525
+ P PL P PL P P P + L T P +
Sbjct: 382 PSP---PLSPLATPPPQAPPALALPPLQAPPSP------PASPPLSPLATPSPQA----- 427
Query: 526 SSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYR 585
P L +Q P + F S PV + T
Sbjct: 428 -------------PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV---SPSATPPSQAP 471
Query: 586 GSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQC 645
S++ P PP P S +++ P + P + + Q
Sbjct: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP------------PPQA 519
Query: 646 RPAAALPDASPGNLEQPPDNM--ETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPA 703
PA A P L PP + + +P LP++ P A PL V P+
Sbjct: 520 PPALATPPLQA--LPSPPASFPGQAPFSPS-ASLPMSPLATPPPQAPPVLAAPLLQVPPS 576
Query: 704 PEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEE 763
P P TL A P G + ++ L + P PP + P
Sbjct: 577 PPASP---------------TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 621
Query: 764 AMSGQQSRNPSSAA---PVQSRGGIGASEN--LENPPKMGEEEALQSQASS 809
+SG SS+A P + RG E +PP E A A S
Sbjct: 622 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 672
>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
Length = 680
Score = 70.5 bits (171), Expect = 2e-11
Identities = 130/529 (24%), Positives = 175/529 (33%), Gaps = 78/529 (14%)
Query: 8 VPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQSTPL 67
+P+G+ GP P N ++ F+ PY ++ A P P P S P
Sbjct: 27 MPTGIKGPLP--NTKTQFFI--PYTIKSKGIAVRGEQGTPGPP--GPAGPRGHPGPSGPP 80
Query: 68 GSSSKSSP-----PVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEP--------LPGPL 114
G SP P L GP PG VP + +GP P LPGP
Sbjct: 81 GKPGYGSPGLQGEPGLPGPPGPSAVGKPG--VPGLPGKPGERGPYGPKGDVGPAGLPGPR 138
Query: 115 TQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHG-- 172
P P ++ PG + A GP P + P +P + G E +G
Sbjct: 139 GPPGPPGIPGPAGISVPGKPGQQGPTGAP-GPRGFPGEKGAPGVPG-MNGQKGEMGYGAP 196
Query: 173 GHP-HGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQ----MPGQWGPVQGGPQPSGQ 227
G P +PG P P GV + QPG++ PG+ GP+ G P P G
Sbjct: 197 GRPGERGLPGPQGPTGPSGP-PGVGKRGENGVPGQPGIKGDRGFPGEMGPI-GPPGPQGP 254
Query: 228 HRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQ 287
P GP G P A P P PG +P +A P P G+ +
Sbjct: 255 ---PGERGPEGIGKPGAAGAPGQPGIPGTKGLPG----APGIAGPPGPPGFGKPGL---- 303
Query: 288 SGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRT 347
P + L PG K E PA P G
Sbjct: 304 ------------------PGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGP 345
Query: 348 HHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSP 407
P G G + ++G +G + G + E S K G G+ D +P
Sbjct: 346 QGPKGIPGSHGLPGPKGETGPAGPAG--YPGAKGERGSPGSDGKPGYPGKPGLDGPKGNP 403
Query: 408 GLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVW----GDTASTGVPDASGSQYE-NVENL 462
GL P VG LPGP A G+ G P G++ +
Sbjct: 404 GLPGPKGDPGVGG----PPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGI 459
Query: 463 EFVQNQEVLPSEPLNLDPSSPSDQFRYGPL--PGPAVPRHGAVCHTGAP 509
+ P P P+ + + GP PGP PR H+G P
Sbjct: 460 PGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRG----HSGEP 504
Score = 36.6 bits (83), Expect = 0.30
Identities = 99/391 (25%), Positives = 123/391 (31%), Gaps = 80/391 (20%)
Query: 1923 PGALGIANPLLAVPAPS-----PEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPP 1977
PG G A P P PS P + SP ++ P P P GP S P P LP
Sbjct: 62 PGPPGPAGPR-GHPGPSGPPGKPGYGSPGLQGEPGLPG--PPGP--SAVGKPGVP-GLPG 115
Query: 1978 GPLEPGP----GCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAP 2033
P E GP G V GPA G P GP PPG+P A PG Q+ P
Sbjct: 116 KPGERGPYGPKGDV--GPA-GLPGPRGPPGPPGIP---------GPAGISVPGKPGQQGP 163
Query: 2034 VG-----------NSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSL 2082
G + G+ P R P PG + +GP+ PP +
Sbjct: 164 TGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGR--PGERGLPG-PQGPTGPSGPP-GV 219
Query: 2083 SPAPETKRPGQAAKKETKEPKKGESWFF-----RWLPGKKKTEAYLPDDKNKSIVWDEKK 2137
E PGQ K + GE + PG++ E K + +
Sbjct: 220 GKRGENGVPGQPGIKGDR-GFPGEMGPIGPPGPQGPPGERGPEGI---GKPGAAGAPGQP 275
Query: 2138 NQWVNLNEPEEEKKAPPPPPTSMPK------TVQAAPPALPGPPGAPVNMYSRRAAGTRA 2191
P A PP P K + P LPG PGA
Sbjct: 276 GIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQ---------- 325
Query: 2192 RYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAA 2251
P+G P + P P IP + +P P E TG GPA
Sbjct: 326 ------GPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGE-------TGPAGPAGY 372
Query: 2252 RGLANPEPAPEPKVLSSAASLPGSELPSSRP 2282
G +P PG + P P
Sbjct: 373 PGAKGERGSPGSDGKPGYPGKPGLDGPKGNP 403
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 66.2 bits (160), Expect = 4e-10
Identities = 128/501 (25%), Positives = 176/501 (35%), Gaps = 96/501 (19%)
Query: 1859 DPQLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQL--- 1915
+P L +PEE L A HL EG + Q P++ +P +E L
Sbjct: 767 EPHLSPQPEEPCLCAVPEEPHLSPQA----EGPHLSPQ----PEELHLSPQTEEPHLSPV 818
Query: 1916 -DRPGLS-QPGALGIA----NPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVP 1969
+ P LS QP ++ P L+ P P H SP + P +P+ P+ P P + P
Sbjct: 819 PEEPCLSPQPEESHLSPQSEEPCLS-PRPEESHLSPELEKPPLSPR--PEKPPEEPGQCP 875
Query: 1970 MFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVP 2029
P LP L P PG + P LG S PG PP + PL E L + S +P + P
Sbjct: 876 A-PEELP---LFPPPGEPSLSPLLGEPALSEPGEPP-LSPLPEELPL---SPSGEPSLSP 927
Query: 2030 QEAP---------------VGNSLSELSEENF--------DGKFANLTPSRTVPDSEAPP 2066
Q P +LS L E + D + P P S PP
Sbjct: 928 QLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISP-PP 986
Query: 2067 GWDRADSGPTQPPLSLSPAPETK-RPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPD 2125
+ D P PP+ L P+P + P E P+ +P P
Sbjct: 987 EANCTDPEPV-PPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP 1045
Query: 2126 DKNKSI------------VWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPAL-- 2171
S+ V DE + L+E E EK + P P P P +
Sbjct: 1046 ALPLSVPSPLSPIGKVVGVSDEAE-----LHEMETEKVSEPECPALEPSATSPLPSPMGD 1100
Query: 2172 ---PGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPI---PS 2225
P P AP + G +D ++ G+Q EP P + L P+ P
Sbjct: 1101 LSCPAPSPAPA-LDDFSGLGEDTAPLDGIDAPGSQ-PEPGQTPGSLASELKGSPVLLDPE 1158
Query: 2226 NLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVL---------------SSAA 2270
L TP P+ G+ P + AP P L ++A
Sbjct: 1159 ELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASA 1218
Query: 2271 SLPGSELPSSRPEGSQGGELS 2291
S PGSE P+ GG LS
Sbjct: 1219 SFPGSEPLLGSPDPEGGGSLS 1239
Score = 60.5 bits (145), Expect = 2e-08
Identities = 103/407 (25%), Positives = 141/407 (34%), Gaps = 67/407 (16%)
Query: 1901 PQQCPGTPSSEMEQL-----DRPGLSQPGALGIANPLLAVP-APSPEHS--SPSVRLLPS 1952
P++ P +P E +L + P P AL ++ PL P +P PE S SP P
Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPF 512
Query: 1953 APQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPAL--GFLEPSGPGLPPGVPPL 2010
+P L + PL+ P P P P PL P P P L P LP PP
Sbjct: 513 SP--LEESPLSPPEESP--PSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPE 568
Query: 2011 QERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDR 2070
R E P P+E+P+ E S + + L+P PP R
Sbjct: 569 ASRLSPPPEESPMSPP--PEESPMSPP-PEASRLFPPFEESPLSPPPEESPLSPPPEASR 625
Query: 2071 ADSGPTQPPLS-------LSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYL 2123
P P+S +SP PE R P ES P ++ +
Sbjct: 626 LSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP--PPEESPTSPP 683
Query: 2124 PDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYS 2183
P+ S ++ + P E+ A PPP S+ P LP P
Sbjct: 684 PEASRLSPPPEDSPT-----SPPPEDSPASPPPEDSLMSLPLEESPLLPLPE-------- 730
Query: 2184 RRAAGTRARYVDVLNPSGTQRSE-PALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDG 2242
P RSE P L+P L+P P +L +P AEEP L
Sbjct: 731 --------------EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL---SPQAEEPHLSPQ 773
Query: 2243 TGR-------EGPAAARGLANPEPAPEPKVLSSAASLPGSELPSSRP 2282
E P + P +P+P+ L + P +E P P
Sbjct: 774 PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLS---PQTEEPHLSP 817
Score = 57.0 bits (136), Expect = 2e-07
Identities = 96/392 (24%), Positives = 133/392 (33%), Gaps = 64/392 (16%)
Query: 1901 PQQCPGTPSSEMEQLDR-PGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLP- 1958
P++ P +P E+ +L P +S+ +PL P SP P L P+ P
Sbjct: 639 PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT 698
Query: 1959 -----DGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPG-----VP 2008
D P + P + +PL PL P P P GP L P +
Sbjct: 699 SPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP-----RSEGPHLSPRPEEPHLS 753
Query: 2009 PLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGW 2068
P E HL +A P P+E L + EE +L+P P P
Sbjct: 754 PRPEEPHLSPQAEEPHLSPQPEEP----CLCAVPEE------PHLSPQAEGPHLSPQPEE 803
Query: 2069 DRADSGPTQPPLS-------LSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEA 2121
+P LS LSP PE +++ P+ ES E
Sbjct: 804 LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHL--------SPEL 855
Query: 2122 YLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNM 2181
P + E+ Q PEE PPP S+ + PAL P P++
Sbjct: 856 EKPPLSPRPEKPPEEPGQ---CPAPEELPLFPPPGEPSLSPLL--GEPALSEPGEPPLSP 910
Query: 2182 YSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPD 2241
L+PSG P L P D PLP P + + A P L
Sbjct: 911 LPEELP---------LSPSGEPSLSPQLMPPD------PLPPPLSPIITA--AAPPALSP 953
Query: 2242 GTGREGPAAARGLANPEPAPEPKVLSSAASLP 2273
E P A+G ++PE +L + S P
Sbjct: 954 LGELEYPFGAKGDSDPESPLAAPILETPISPP 985
Score = 56.6 bits (135), Expect = 3e-07
Identities = 95/362 (26%), Positives = 129/362 (35%), Gaps = 61/362 (16%)
Query: 1901 PQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRL-------LPSA 1953
P++ P +P E +L P P + P + +P PE S S+ L LP
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTS---PPPEDSPASPPPEDSLMSLPLEESPLLPLPEE 731
Query: 1954 PQTLP--DGPLASPARVPMFPVPLPPGP----------LEPGPG--CVTPGPALGFLEPS 1999
PQ P +GP SP P P P L P P C+ P L P
Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQ 791
Query: 2000 GPGLPPGVPPLQERRHLLQEARSPDPGIVPQEA-----PVGNSLSELSEENFDGKFANLT 2054
G P + P E HL + P VP+E P + LS SEE L+
Sbjct: 792 AEG--PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPC------LS 843
Query: 2055 P----SRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFF 2110
P S P+ E PP R + P +P PAPE + + P GE
Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPPEEP--GQCPAPEELPLFPPPGEPSLSPLLGEPALS 901
Query: 2111 RWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPA 2170
PG+ LP++ S + + P+ P PPP S P AAPPA
Sbjct: 902 E--PGEPPLSP-LPEELPLSPSGEPSLS-------PQLMPPDPLPPPLS-PIITAAAPPA 950
Query: 2171 LPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVP 2230
L P G + + D +P E ++P P P+P + P
Sbjct: 951 L-SPLGELEYPFGAKGDS------DPESPLAAPILETPISPPPEANCTDPEPVPPMILPP 1003
Query: 2231 TP 2232
+P
Sbjct: 1004 SP 1005
Score = 56.2 bits (134), Expect = 4e-07
Identities = 94/387 (24%), Positives = 133/387 (34%), Gaps = 55/387 (14%)
Query: 1901 PQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDG 1960
P + TP+ E + L QP + + P P + P L + Q P
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKP---LGKAGVQLEPQL 430
Query: 1961 PLASPARVPMFPVPLPPGPLEPGP--GCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQ 2018
+P+ P P PL P P +P P L P LP PL E HL +
Sbjct: 431 EAPLNEEMPLLPPP-EESPLSPPPEESPTSPPPEASRLSPPPEELPAS--PLPEALHLSR 487
Query: 2019 EARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQP 2078
P+E+P LS F+ L S P E+PP S +
Sbjct: 488 PLEESPLSPPPEESP-------LSPPPESSPFSPLEESPLSPPEESPP------SPALET 534
Query: 2079 PLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYL---PDDKNKSIVWDE 2135
PLS P PE ++ P E LP EA P +++
Sbjct: 535 PLS--PPPEASPLSPPFEESPLSPPPEE------LPTSPPPEASRLSPPPEESP------ 580
Query: 2136 KKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVD 2195
++ P EE PPP S P P P +P+ S +R
Sbjct: 581 -------MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPL---SPPPEASRLSPPP 630
Query: 2196 VLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLA 2255
+P E ++P V+ L+PLP+ S L P ++ P+ + P A L+
Sbjct: 631 EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLS 690
Query: 2256 NPEPAPEPKVLSSAASLPGSELPSSRP 2282
P PE S S P + P+S P
Sbjct: 691 ---PPPE----DSPTSPPPEDSPASPP 710
Score = 52.0 bits (123), Expect = 7e-06
Identities = 99/401 (24%), Positives = 133/401 (33%), Gaps = 73/401 (18%)
Query: 1903 QCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPL 1962
+ P TP + + PGL G P APSP PS P G
Sbjct: 2328 KAPLTPRASQVEPQSPGL---GLRPQEPPPAQALAPSP----------PSHPDIFRPGSY 2374
Query: 1963 ASP-ARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEAR 2021
P A+ P+ P P PP P C P +L PS P VP + + Q
Sbjct: 2375 TDPYAQPPLTPRPQPP---PPESCCALPPRSL----PSDPF--SRVPASPQSQSSSQSPL 2425
Query: 2022 SPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGP-TQPPL 2080
+P P LS E F PS P ++P + R S P ++ P
Sbjct: 2426 TPRP---------------LSAEAF-------CPSPVTPRFQSPDPYSRPPSRPQSRDPF 2463
Query: 2081 SLSPAPETKRPGQAAKK--ETKEPKKGESWFFRWLPGKKKTE--AYLPDDKNKSIVWDEK 2136
+ P +P + A K G F LP E A +P + + V
Sbjct: 2464 APLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPG 2523
Query: 2137 KNQWVNLNEPE---------EEKKAPPPPPTSMPKTVQAAPPALPGPP-GAPVNMYSRRA 2186
+V P E PP P +P PGP G P + A
Sbjct: 2524 TGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVA 2583
Query: 2187 AGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGRE 2246
G +PSG+ P+ L+PL PS L P PD P L G +
Sbjct: 2584 TGN-------FHPSGSPLG-PSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQR 2635
Query: 2247 GPAAARGLANPEPAPEPKVLSSAASLPGSELPSSRPEGSQG 2287
G+ +P E +SL +ELP ++ G G
Sbjct: 2636 S-----GITSPVEKREDPGTGMGSSLATAELPGTQDPGMSG 2671
Score = 48.9 bits (115), Expect = 6e-05
Identities = 108/432 (25%), Positives = 146/432 (33%), Gaps = 140/432 (32%)
Query: 1918 PGLSQPGALGIANPLLA---VPAPSPEHSSPSVRL---LPSAPQTLPD--GPLASPARVP 1969
PG PG L + P VP+ P +P+ L P+AP T P P +PA+ P
Sbjct: 2151 PGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPP 2210
Query: 1970 MFPVPLPPGPLEPG------PGC-----VTPGPALGFLEPSGPGL-------PPGV---- 2007
M PG +PG PG TP P FL+P P L PGV
Sbjct: 2211 MLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDP---FLKPRCPSLDNLAVPESPGVGGGK 2267
Query: 2008 --------PPLQERRHLLQEARS-----------PDPGIVPQEAPVGNSLSELSEENFDG 2048
PP E R L+ + P+ G V + G L L + D
Sbjct: 2268 ASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSS-GTHLGGLELKTPDV 2326
Query: 2049 KFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPA--PETKRPGQAAKKETKEPKKGE 2106
A LTP + + ++P R P L+ SP P+ RPG
Sbjct: 2327 FKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPG-------------- 2372
Query: 2107 SWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQA 2166
T+ Y +P + PPPP S
Sbjct: 2373 ----------SYTDPYA---------------------QPPLTPRPQPPPPESC------ 2395
Query: 2167 APPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSN 2226
ALP P P + +SR A +++ S +Q +PL P P+ +
Sbjct: 2396 --CALP-PRSLPSDPFSRVPASPQSQ-------SSSQ------------SPLTPRPLSAE 2433
Query: 2227 LFVPTPDAEEPQLPDGTGR--EGPAAARGLA----NPEPAPEPKVLSSAASLPGSEL--- 2277
F P+P Q PD R P + A P P P P+V A SL + L
Sbjct: 2434 AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQP-PEVAFKAGSLAHTSLGAG 2492
Query: 2278 --PSSRPEGSQG 2287
P++ P G G
Sbjct: 2493 GFPAALPAGPAG 2504
Score = 47.4 bits (111), Expect = 2e-04
Identities = 100/406 (24%), Positives = 137/406 (33%), Gaps = 82/406 (20%)
Query: 1 MQPPPQTVPSGMA---------------GPPPAGNPRSVFWASSPY-----------RRR 34
+ PPP+ +P+ PPP +P S SSP+
Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEES 526
Query: 35 ANNNAAVAPTTCP--LQPVTDPFAFS-----RQALQSTPLGSSSKSSPPVLQGP------ 81
+ A P + P P++ PF S + L ++P +S+ SPP + P
Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE 586
Query: 82 -APAGFSQHPGLLVPHTHARDSSQGPCE-PLPGPLTQPRAHASPFSGALTP-----SAPP 134
+P L P S P E PL P R P ++P P
Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSP 646
Query: 135 GPEMNRSAEVGP----SSEPEVQTLPYLPHYIP-GVDPETSHGGHPHGNMPGL----DRP 185
PE++R + + S PE L P P PE S P + P D P
Sbjct: 647 PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706
Query: 186 LSRQNPHDGVVTPAASPS----LPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPS-- 239
S P D +++ S LP+ P GP P+P H SP PE P S
Sbjct: 707 AS-PPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGP-HLSPRPEEPHLSPRPEEPHLSPQ 764
Query: 240 ----------GVPCATSVPHFPTPSILHQGP-----GHEQH-SPLVAPPAALPSDGRDEV 283
PC +VP P S +GP E H SP P P +
Sbjct: 765 AEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCL 824
Query: 284 SHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRP 329
S SHL+ S+ +PR SPEL + P +P
Sbjct: 825 SPQPEESHLSPQSEEPCL---SPRPEESHLSPELEKPPLSPRPEKP 867
Score = 46.6 bits (109), Expect = 3e-04
Identities = 128/542 (23%), Positives = 189/542 (34%), Gaps = 77/542 (14%)
Query: 647 PAAALPDASPGNLEQPPDNMETLCA-----------PQVCPLP----LNSTTEAVHMLPH 691
P + P+ SP + P D++ +L PQ+CP L+ E H+ P
Sbjct: 697 PTSPPPEDSPAS-PPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPR 755
Query: 692 AGAPPLDTVYPAPEKRPSARTQGPVKCESPATT-LWAQSELPDFGGN---VLLAPAAPAL 747
P L A E S + + P C P L Q+E P + L+P
Sbjct: 756 PEEPHLSP--QAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813
Query: 748 YVCAKPQPPVVQP-PEEAMSGQQSRNPS-SAAPVQSRGGIGASENLENPPKMGEEEALQS 805
++ P+ P + P PEE+ QS P S P +S S LE PP E
Sbjct: 814 HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESH----LSPELEKPPLSPRPEKPPE 869
Query: 806 QASSGYASL---LSSPPTESLQNPPVLIAQPDHSYNLAQPIN---FSVSLSNSHEKNQSW 859
+ A L PP E +P L+ +P S P++ + LS S E
Sbjct: 870 EPGQCPAPEELPLFPPPGEPSLSP--LLGEPALSEPGEPPLSPLPEELPLSPSGE----- 922
Query: 860 REALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLP---SSVAQSNFPQGS-GASE 915
P++S + D P S +++ + P S + + +P G+ G S+
Sbjct: 923 --------PSLSPQLMPPDPLPP------PLSPIITAAAPPALSPLGELEYPFGAKGDSD 968
Query: 916 MVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLV---PPAHG 972
S A +L P S P N + + LP SP G S +L+ PP
Sbjct: 969 PESPLAAPILETPISPPPEANC---TDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCS 1025
Query: 973 TLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGP 1032
L+ +S + + AL ++ L V S L ++ + S P
Sbjct: 1026 PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMET----EKVSEP 1081
Query: 1033 GAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQ 1092
P L+ G L P S A + P S P GQ
Sbjct: 1082 ECPALEPSATSPLPSPMGD--LSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQ 1139
Query: 1093 AQNSAQSP--ASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPG 1150
S S S VL+D + P P + ++G G E+P PV AP
Sbjct: 1140 TPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEP-RAPV---APT 1195
Query: 1151 PP 1152
PP
Sbjct: 1196 PP 1197
Score = 45.4 bits (106), Expect = 6e-04
Identities = 124/554 (22%), Positives = 182/554 (32%), Gaps = 124/554 (22%)
Query: 2 QPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQA 61
QPPP P PP P S P+ R + + + + PL P S +A
Sbjct: 2388 QPPP---PESCCALPPRSLP------SDPFSRVPASPQSQSSSQSPLTPRP----LSAEA 2434
Query: 62 LQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPL-PGPLTQPR-- 118
+P+ P Q P P +S+ P +R S+ P PL P QP
Sbjct: 2435 FCPSPV-------TPRFQSPDP--YSRPP--------SRPQSRDPFAPLHKPPRPQPPEV 2477
Query: 119 -------AHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYI--PGVDPET 169
AH S +G + P GP A+V PS +P P+++ PG
Sbjct: 2478 AFKAGSLAHTSLGAGGFPAALPAGPAGELHAKV-PSGQP--------PNFVRSPGT---- 2524
Query: 170 SHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQW------GPVQGGPQ 223
G G P+ P V P+ P +PQPGL P GP G PQ
Sbjct: 2525 -------GAFVGTPSPMRFTFPQ-AVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQ 2576
Query: 224 PSGQ-------HRSPCPEGPVPSGV----------PCATSVPHFPTPSILHQGPGHEQHS 266
+ H S P GP P + P P S+ + G Q S
Sbjct: 2577 STNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRS 2636
Query: 267 PLVAPPAALPSDGRDEVSHLQSGSHLANNSDPEST---------FRQNPRIVNHWASPEL 317
+ +P G S L + + L DP + RQ R+ ++
Sbjct: 2637 GITSPVEKREDPGTGMGSSLAT-AELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQI 2695
Query: 318 RQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQ 377
++N ++ E A+A + S P G P S + +
Sbjct: 2696 QRNT-LRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGL--- 2751
Query: 378 GGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLC--------QALLP 429
LS G G DD S P P+ V + L +A P
Sbjct: 2752 -----PPSKLSGPILG-PGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYP 2805
Query: 430 G--PSNEAAGDVWGD---TASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPS 484
G P + +W TA+T + A +++ + E + P ++ P
Sbjct: 2806 GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPG 2865
Query: 485 DQFRYGPLPGPAVP 498
+ P+PGPA P
Sbjct: 2866 E-----PVPGPAGP 2874
Score = 44.7 bits (104), Expect = 0.001
Identities = 153/657 (23%), Positives = 221/657 (33%), Gaps = 147/657 (22%)
Query: 1 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQ--PVTDPFAFS 58
+ PPP+ P PPP +P S P R + +PT+ P + P + P
Sbjct: 662 LSPPPEESP---LSPPPEESPTS----PPPEASRLSPPPEDSPTSPPPEDSPASPP---P 711
Query: 59 RQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQ-- 116
+L S PL S P P H L P S P EP P +
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPH---LSPRPEEPHLSPRPEEPHLSPQAEEP 768
Query: 117 --------PRAHASPFSGALTPSAPPGPEMNRSAE---VGPSSE-PEVQTLPYLPHYIPG 164
P A P L+P A GP ++ E + P +E P + +P P P
Sbjct: 769 HLSPQPEEPCLCAVPEEPHLSPQAE-GPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSP- 826
Query: 165 VDPETSH----------GGHPHGN--MPGLDRPLSRQNPHDGVVTP-------------- 198
PE SH P + P L++P P P
Sbjct: 827 -QPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP 885
Query: 199 ----AASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPS 254
+ SP L +P L PG+ P P+P +P + S +P
Sbjct: 886 PGEPSLSPLLGEPALSEPGE-----------------PPLSPLPEELPLSPSGEPSLSPQ 928
Query: 255 ILHQGPGHEQHSPLV---APPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQ------- 304
++ P SP++ APPA P + L+ +SDPES
Sbjct: 929 LMPPDPLPPPLSPIITAAAPPALSP------LGELEYPFGAKGDSDPESPLAAPILETPI 982
Query: 305 NPRIVNHWASPE------LRQNPGVKNEHRPAS-ALVNPLARGDSPENRTHHPLGAGAGS 357
+P + PE L +PG + PAS L+ PL SP + S
Sbjct: 983 SPPPEANCTDPEPVPPMILPPSPG--SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPS 1040
Query: 358 GCA----PLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPP 413
C+ PL S S + E E E + +EK + +S P
Sbjct: 1041 QCSPPALPLSVPSPLSPIGKVVGVSDEAELHE-METEKVSEPECPALEPSATS------P 1093
Query: 414 APTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVE-----------NL 462
P+ +G S C A P P+ + + DTA DA GSQ E + +
Sbjct: 1094 LPSPMGDLS-CPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSP 1152
Query: 463 EFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDA-TLHTVHPDSV 521
+ +E+ P P+ + P + P PR AP A T T+ +
Sbjct: 1153 VLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPR--------APVAPTPPTLIKSDI 1204
Query: 522 SSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQI----DSSPVGGE 574
+ S+ S G S S E + +G P+ E GS ++ D SP E
Sbjct: 1205 VNEISNLSQGDASASFPGSEPL-------LGSPDPEGGGSLSMELGVSTDVSPARDE 1254
Score = 43.9 bits (102), Expect = 0.002
Identities = 78/320 (24%), Positives = 110/320 (34%), Gaps = 70/320 (21%)
Query: 63 QSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHAS 122
QS LG + PP Q AP+ S HP + P ++ +Q P P P P P +
Sbjct: 2341 QSPGLGLRPQEPPPA-QALAPSPPS-HPDIFRPGSYTDPYAQPPLTPRPQP-PPPESCC- 2396
Query: 123 PFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGL 182
AL P + P +R P S+ Q+ P
Sbjct: 2397 ----ALPPRSLPSDPFSR-VPASPQSQSSSQS-------------------------PLT 2426
Query: 183 DRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQP----SGQHRSPCPEGP-- 236
RPLS + A PS P Q P + PQ + H+ P P+ P
Sbjct: 2427 PRPLSAE---------AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEV 2477
Query: 237 -VPSGVPCATSVPHFPTPSILHQGPGHEQHS--PLVAPPAALPSDGRDEVSHLQSGSHLA 293
+G TS+ P+ L GP E H+ P PP + S G +G+ +
Sbjct: 2478 AFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPG--------TGAFVG 2529
Query: 294 NNSDPESTFRQ---NPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHP 350
S TF Q P + P L G+ + P L P + + HP
Sbjct: 2530 TPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHP 2589
Query: 351 LGAGAGSGCAPLEADSGASG 370
G +PL SG++G
Sbjct: 2590 SG-------SPLGPSSGSTG 2602
Score = 42.4 bits (98), Expect = 0.005
Identities = 60/244 (24%), Positives = 87/244 (35%), Gaps = 19/244 (7%)
Query: 109 PLPGPLTQPRAHASPFSGALTPSAPPGPEMNRSAE----------VGPSSEPEV--QTLP 156
P PG L P A+P +P+ P G ++ SA+ GP S E+ + P
Sbjct: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAG--LSTSADGFLKPPAGSVPGPDSPGELFLKLPP 2165
Query: 157 YLPHYIPGVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWG 216
+P +P DP +P P P PA P L GQ G
Sbjct: 2166 QVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSP-TGAPAQPPMLGASSRPGAGQPG 2224
Query: 217 PVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALP 276
P + +H+ P P P P S+ + P G G + PL++PP
Sbjct: 2225 EFHTTPPGTPRHQ---PSTPDPFLKPRCPSLDNLAVPESPGVGGG-KASEPLLSPPPFGE 2280
Query: 277 SDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNP 336
S EV + G+ + P F +P H EL+ K P ++ V P
Sbjct: 2281 SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEP 2340
Query: 337 LARG 340
+ G
Sbjct: 2341 QSPG 2344
Score = 40.8 bits (94), Expect = 0.016
Identities = 90/385 (23%), Positives = 127/385 (32%), Gaps = 45/385 (11%)
Query: 880 GENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVP 939
G T+ +G+ TS+ L P+ + P E+ P + Q PSQ P L P
Sbjct: 2127 GSPTTPAGLSTSADGFLKPPAG----SVPGPDSPGELFLKLPPQVPAQVPSQD-PFGLAP 2181
Query: 940 ESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLS 999
+ + +A P + P+ T PP G G H T
Sbjct: 2182 AYPLEPRFPTAPPTYPPYPS-PTGAPAQPPMLGASSRPGAGQPGEFHT---------TPP 2231
Query: 1000 RTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQ 1059
T + + +P S ++A P G G + + LE ++
Sbjct: 2232 GTPRHQPSTPDPFLKPRCPSLDNLAV-PESPGVGGGKASEPLLSPPPFGESRKALEVKKE 2290
Query: 1060 ELVPPQQQASPPQL-----PKAMFS----ELSNPESLPAQGQAQNSAQSPASLVL----- 1105
EL PP L P + EL P+ A + S P S L
Sbjct: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ 2350
Query: 1106 -VDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQ-PVPALAPGPPPQDLAAYYYYR 1163
Q L P PP + S + A P P PQ P P PP+ L + + R
Sbjct: 2351 EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSR 2410
Query: 1164 -PLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPS 1222
P Q P P P +A + S PR++ D Y P P RP
Sbjct: 2411 VPASPQSQSSSQSPLTPRPLSAEAFCP---SPVTPRFQSPD--------PYSRP-PSRPQ 2458
Query: 1223 SRASHSSERPPPRQGYPEGYYSSKS 1247
SR + PPR PE + + S
Sbjct: 2459 SRDPFAPLHKPPRPQPPEVAFKAGS 2483
Score = 40.0 bits (92), Expect = 0.027
Identities = 61/228 (26%), Positives = 79/228 (34%), Gaps = 36/228 (15%)
Query: 106 PCEPLPGPLTQPRA-----HASPFSGALTPSAP--PGP---EMNRSAEVGPSSEPEVQT- 154
P EP P +P A P G +T P PGP E + G EP+++
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433
Query: 155 ----LPYLPHYIPGVDPETSHGGHPHGNMPGLDRP-LSRQNPHDGVVTPAASPS------ 203
+P LP PE S P P P SR +P + + P
Sbjct: 434 LNEEMPLLP------PPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSR 487
Query: 204 -LPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPV--PSGVPC--ATSVPHFPTPSILHQ 258
L + L P + P+ P P SP E P+ P P A P P P
Sbjct: 488 PLEESPLSPPPEESPLS--PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPL 545
Query: 259 GPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNP 306
P E+ SPL PP LP+ E S L + S P +P
Sbjct: 546 SPPFEE-SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592
Score = 39.3 bits (90), Expect = 0.046
Identities = 65/278 (23%), Positives = 105/278 (37%), Gaps = 33/278 (11%)
Query: 929 PSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQE 988
P +P P L E++ KAG L +P +L PP L P ++ S E
Sbjct: 406 PKEPGP--LQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPE 463
Query: 989 DTYGAL--DFTLSRTLENPVNVYNPSHSDSLAS--QQSVASHPRQSGPGAPNLDRFYQQV 1044
+ + + + L +++ P L+ ++S S P +S P +P L+
Sbjct: 464 ASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSP-LEESPLSP 522
Query: 1045 TKDAQGQPGLERA------QQELVPPQQQA--SPP--QLPKAMFSELSN----PESLPAQ 1090
+++ P LE L PP +++ SPP +LP + E S PE P
Sbjct: 523 PEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582
Query: 1091 GQAQNSAQSPASLVLVDAGQQLPP-------RPPQSSSVSLVSSGSGQAAVPSEQPWPQP 1143
+ S SP +A + PP PP+ S +S S + P + P P
Sbjct: 583 PPPEESPMSPPP----EASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP 638
Query: 1144 VPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEP 1181
P +P PP +++ + P P P P
Sbjct: 639 -PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
Score = 38.9 bits (89), Expect = 0.060
Identities = 69/294 (23%), Positives = 102/294 (34%), Gaps = 40/294 (13%)
Query: 1 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 60
+QP PQ PS + PP P S + + + + P
Sbjct: 4078 VQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLL--- 4134
Query: 61 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQ---- 116
A S LG S L GP Q P L P ++ GP P PGP+ Q
Sbjct: 4135 AQPSVSLGDQPGSMTQNLLGP------QQPMLERP----MQNNTGPQPPKPGPVLQSGQG 4184
Query: 117 -PRAHASPFSGALTPSAPPGPEMN-RSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGH 174
P P G L N + + P + ++Q L +
Sbjct: 4185 LPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQAL---------LMQRQLQQSQ 4235
Query: 175 PHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQ---GGPQPSGQHRSP 231
P P ++ +P G++ PQ G Q GP+Q GP+P G R P
Sbjct: 4236 AVRQTPPYQEPGTQTSPLQGLL-----GCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLP 4290
Query: 232 CPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSH 285
P G + +G P V P PS + ++ S L +P + LP++ + +H
Sbjct: 4291 APPGALSTG-PVLGPVHPTPPPSSPQE---PKRPSQLPSPSSQLPTEAQLPPTH 4340
Score = 38.1 bits (87), Expect = 0.10
Identities = 154/655 (23%), Positives = 226/655 (34%), Gaps = 140/655 (21%)
Query: 587 SVSQPSTP-----SPPKPTGIFQTSANSSF-----EPVKSHLVGVKPFEAD----RANVV 632
SV++ TP SPP+P ++ + +P H+ ++P E A +
Sbjct: 360 SVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPL 419
Query: 633 GEVRETCVRQKQC-----RPAAALPDASPGNLEQPPDNMETLCAPQVC-------PLPLN 680
G+ Q + P P+ SP L PP+ T P+ LP +
Sbjct: 420 GKAGVQLEPQLEAPLNEEMPLLPPPEESP--LSPPPEESPTSPPPEASRLSPPPEELPAS 477
Query: 681 STTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLL 740
EA+H+ PL P PE+ P + P SP + L P
Sbjct: 478 PLPEALHLSRPLEESPLS---PPPEESPLS----PPPESSPFSPLEESPLSPPEE----- 525
Query: 741 APAAPALYVCAKPQPPVVQPPEEA-MSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGE 799
+P +PAL + P+ PPE + +S +P S P E +PP
Sbjct: 526 SPPSPAL------ETPLSPPPEASPLSPPFEESPLSPPP---------EELPTSPPPE-- 568
Query: 800 EEALQSQASSGYASLLSSPPTESLQNPP---VLIAQPDHSYNLAQPINFSVSLSNSHEKN 856
AS LS PP ES +PP ++ P + L P S LS E
Sbjct: 569 ------------ASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEES-PLSPPPE-- 613
Query: 857 QSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQ-SNFPQGSGASE 915
E+ + P S + E++ +S P S +S P V++ S P S S
Sbjct: 614 ----ESPLSPPPEASRLS---PPPEDSPMSPPPEES--PMSPPPEVSRLSPLPVVSRLSP 664
Query: 916 MVSNQPANLLVQPPSQPVPENLVPESQK------DRKAGSALPGFANSPAGSTSVVLVPP 969
P + PP + P + PE+ + D SP S++ +P
Sbjct: 665 PPEESP----LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720
Query: 970 AHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPS--HSDSLASQQSVASHP 1027
L+P + E + LS E P P H A + ++ P
Sbjct: 721 EESPLLPLPEEPQLCPRSEGPH------LSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP 774
Query: 1028 RQ----SGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELS- 1082
+ + P P+L + A+G P L +EL Q P P LS
Sbjct: 775 EEPCLCAVPEEPHL-------SPQAEG-PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSP 826
Query: 1083 NPESLPAQGQAQNSAQSPASLVLVDAGQQLPP---RPPQSSSVSLVSSGSGQAAVPSEQP 1139
PE Q++ SP L P +PP S GQ P E P
Sbjct: 827 QPEESHLSPQSEEPCLSPR-----PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELP 881
Query: 1140 -WPQP----------VPALA-PGPPPQDLAAYYYYRPLYDAYQPQYSLP-YPPEP 1181
+P P PAL+ PG PP L+ PL + +P S PP+P
Sbjct: 882 LFPPPGEPSLSPLLGEPALSEPGEPP--LSPLPEELPLSPSGEPSLSPQLMPPDP 934
Score = 36.6 bits (83), Expect = 0.30
Identities = 51/191 (26%), Positives = 65/191 (34%), Gaps = 42/191 (21%)
Query: 2 QPPPQTVPSGM-------AGPPPAGNPRSVFWASSPYRRRANN----NAAVAPTTCPLQ- 49
+PPP PS M G A R+ + S P +++ A A T+
Sbjct: 2774 RPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAM 2833
Query: 50 ----PVTDPFAFSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQG 105
P T RQAL S G S++ P P PAG P + H G
Sbjct: 2834 SARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAG----PAQFIELRHNVQKGLG 2889
Query: 106 PC-EPLPGPLTQPRAHASPFSG-------------------ALTPSAPPGPEMNRSAEVG 145
P P PG R P S PSAPP PE+N S +
Sbjct: 2890 PGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNS--LH 2947
Query: 146 PSSEPEVQTLP 156
P+ + TLP
Sbjct: 2948 PTPHTKGPTLP 2958
Score = 35.0 bits (79), Expect = 0.87
Identities = 133/656 (20%), Positives = 224/656 (34%), Gaps = 109/656 (16%)
Query: 163 PGVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGP 222
PGV + G P G MP + H G++ SP PQ G Q G GP Q
Sbjct: 3761 PGVQTNQALGPKPQGLMP--------PSSHQGLLVQQLSPQPPQ-GPQ--GMLGPAQVAV 3809
Query: 223 QPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDE 282
+ P+GP + + V +P + QG G H + A + +
Sbjct: 3810 LQQQHPGALGPQGPHRQVLMTQSRV--LSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQ 3867
Query: 283 -----VSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPL 337
+SHLQ S ++++ P+ + + + +L+Q ++ + + L
Sbjct: 3868 GSMAGLSHLQQ-SLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQL 3926
Query: 338 ARGDSPENRTHHPLGAGAGSGCAPLEAD-SGASGALAMFFQGGETENEENLSSEKAGLSG 396
+ + + L + FQ + + + L ++ L
Sbjct: 3927 QQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLS 3986
Query: 397 --QADFDDFCSSPGLGRPPAPTHVGAGSLCQALL----------PGPSNEAAGDVWGDTA 444
Q PG+ P G+L LL P S+EA G +
Sbjct: 3987 PQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE---GPST 4043
Query: 445 STGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVC 504
G P A G+ E+ + +EP + PS D P P P+ ++
Sbjct: 4044 HQGGPLAIGTTPES------------MATEPGEVKPSLSGDSQLLLVQPQPQ-PQPSSL- 4089
Query: 505 HTGAPDATLHTVHPDSVSSSYSSR--SHGRL-SGSARPQELVGTFIQQEVGKPEDEASGS 561
P L VS +++ SHG+L SGS+ V + Q D+ GS
Sbjct: 4090 -QLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQP-GS 4147
Query: 562 FFKQIDSSPVGGETDETT-VSQNYRGSVSQPSTPSPPKPTGIFQTSAN-------SSFEP 613
+ + +G + QN G P PPKP + Q+ +
Sbjct: 4148 MTQNL----LGPQQPMLERPMQNNTG-------PQPPKPGPVLQSGQGLPGVGIMPTVGQ 4196
Query: 614 VKSHLVGVKPFEADRANVVGEVRE---TCVRQKQCRPAAAL----PDASPGNLEQPPDNM 666
+++ L GV ++ + ++ + Q+Q + + A+ P PG P +
Sbjct: 4197 LRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGL 4256
Query: 667 ETLCAPQV--CPLPLNSTTEAVHMLPHAGAPP--------------LDTVYPAPEKRPSA 710
C PQ+ P P + + P PP L V+P P
Sbjct: 4257 LG-CQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQ 4315
Query: 711 RTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMS 766
+ P + SP++ L +++LP P P KPQ P ++PP +S
Sbjct: 4316 EPKRPSQLPSPSSQLPTEAQLP---------PTHPG---TPKPQGPTLEPPPGRVS 4359
Score = 34.7 bits (78), Expect = 1.1
Identities = 57/226 (25%), Positives = 88/226 (38%), Gaps = 72/226 (31%)
Query: 1883 VERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEH 1942
++RQ+++ V P Q PGT +S ++ G LG L P P
Sbjct: 4227 MQRQLQQSQAVRQTP---PYQEPGTQTSPLQ----------GLLGCQPQLGGFPGPQ--- 4270
Query: 1943 SSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPG 2002
+ ++ L + P+ P GP P P P PG ++ GP LG + P+
Sbjct: 4271 -TGPLQELGAGPR--PQGP-------PRLPAP---------PGALSTGPVLGPVHPT--- 4308
Query: 2003 LPPGVPPLQERRHLLQEARSPDPGI-VPQEAPVGNSLSELSEENFDGKFANLTPSRTVPD 2061
PP P + +R ++ P P +P EA + + TP P
Sbjct: 4309 -PPPSSPQEPKR----PSQLPSPSSQLPTEAQLPPTHPG-------------TPKPQGPT 4350
Query: 2062 SEAPPG------WDRADS------GPTQPPLSLSPAPETKRPGQAA 2095
E PPG AD+ GP PP +L+ ET++P Q++
Sbjct: 4351 LEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA---ETQKPEQSS 4393
Score = 34.3 bits (77), Expect = 1.5
Identities = 44/184 (23%), Positives = 63/184 (34%), Gaps = 13/184 (7%)
Query: 1061 LVPPQQQASPPQLPKAMF-------SELSNP-ESLPAQGQAQNSAQSPASLVLVDAGQQL 1112
L PP ++ LP+A+ S LS P E P ++S SP + ++
Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEES 526
Query: 1113 PPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQ--DLAAYYYYRPLYDAYQ 1170
PP P + +S S + E P P L PPP+ L+ P+
Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPM---SP 583
Query: 1171 PQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSE 1230
P P P P A+ L+ S P + A P + P S S
Sbjct: 584 PPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESP 643
Query: 1231 RPPP 1234
PP
Sbjct: 644 MSPP 647
Score = 34.3 bits (77), Expect = 1.5
Identities = 125/517 (24%), Positives = 175/517 (33%), Gaps = 116/517 (22%)
Query: 1883 VERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEH 1942
V + EG HQ G P TP S + PG +P G + LL P P P+
Sbjct: 4033 VSSEATEGPST-HQGG--PLAIGTTPESMATE---PGEVKPSLSGDSQLLLVQPQPQPQP 4086
Query: 1943 SS----PSVRLLPSAPQTLP---------DGPLASPARVPMFPVP----LPPGPLEPGPG 1985
SS P +RL Q + G L S + VP P L PG
Sbjct: 4087 SSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPG 4146
Query: 1986 CVTP---GPALGFLEP-----SGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNS 2037
+T GP LE +GP P P LQ + L P GI+P +
Sbjct: 4147 SMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGL------PGVGIMPTVGQLRAQ 4200
Query: 2038 LSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKK 2097
L + +N + +L+P + + + Q L S A P Q
Sbjct: 4201 LQGVLAKN--PQLRHLSPQQQ----------QQLQALLMQRQLQQSQAVRQTPPYQEPGT 4248
Query: 2098 ETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPP 2157
+T P +G L G + P + P +E A P P
Sbjct: 4249 QTS-PLQG-------LLGCQPQLGGFPGPQTG----------------PLQELGAGPRPQ 4284
Query: 2158 TSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAP 2217
PP LP PPGA + G V P + + EP P+ +P
Sbjct: 4285 ---------GPPRLPAPPGA-------LSTGPVLGPVHPTPPPSSPQ-EPK-RPSQLPSP 4326
Query: 2218 LAPLPIPSNL---FVPTPDAEEPQLPDGTGREGPAAA--------RGLANPEPAPEPKVL 2266
+ LP + L TP + P L GR PAAA +GL +P P L
Sbjct: 4327 SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDP---PDNL 4383
Query: 2267 SSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPA------AGGP 2320
+ S L + G + S +S + Q + P L A A G
Sbjct: 4384 AETQKPEQSSLVPGHLDQVNGQVVPEASQLS-----IKQEPREEPCALGAQSVKREANGE 4438
Query: 2321 PSGAMPFYNPAQLAQACATSGSSRLGRIGQRKHLVLN 2357
P GA N LA + +G L ++ + K++ L+
Sbjct: 4439 PIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLS 4475
Score = 33.9 bits (76), Expect = 1.9
Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 1/70 (1%)
Query: 1937 APSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLP-PGPLEPGPGCVTPGPALGF 1995
AP PE SP L +P + P PL P+ P+P P PL P P P
Sbjct: 4908 APPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967
Query: 1996 LEPSGPGLPP 2005
E PP
Sbjct: 4968 PEEGEDSRPP 4977
Score = 33.5 bits (75), Expect = 2.5
Identities = 38/140 (27%), Positives = 55/140 (39%), Gaps = 13/140 (9%)
Query: 1020 QQSVASH---PRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKA 1076
QQS+ SH P+ S +L + QQ + Q Q L++ QQ+ + QQQ QL
Sbjct: 3877 QQSLMSHSGQPKLSAQPMGSLQQLQQQ--QQLQQQQQLQQQQQQQLQQQQQLQQQQL--- 3931
Query: 1077 MFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPS 1136
+ + L Q Q Q Q QQ + Q + L++ + S
Sbjct: 3932 --QQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQ---SRTLLS 3986
Query: 1137 EQPWPQPVPALAPGPPPQDL 1156
Q Q AL PG P + L
Sbjct: 3987 PQQQQQQQVALGPGMPAKPL 4006
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 65.9 bits (159), Expect = 5e-10
Identities = 99/368 (26%), Positives = 136/368 (36%), Gaps = 67/368 (18%)
Query: 1934 AVPAPSPEHSSPSVRLLPSAP-QTLPDG--PLASPARVPMFPVPLPPGPLEPGPGCVTPG 1990
A+P P PE P V P AP + +P+ P A P + + PV +P P E P P
Sbjct: 10569 AIP-PKPESPPPEV---PEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPV 10624
Query: 1991 PALGFLEPSGPGLP----PGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENF 2046
P P P +P P VP + + EA P P E+P E E
Sbjct: 10625 P-----PPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKP-----ESPPPEVFEEPEEVAL 10674
Query: 2047 DGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGE 2106
+ A + P+ APP T PP P PE K P AKK P K
Sbjct: 10675 EEPPAEVVEE---PEPAAPP-------QVTVPP--KKPVPEKKAPAVVAKKPELPPVK-- 10720
Query: 2107 SWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQA 2166
+P K +P+ K +V KK + PE K+ P ++PK +
Sbjct: 10721 ------VPEVPK--EVVPEKKVPLVV--PKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEV 10770
Query: 2167 APPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEP-ALAPADFVAPLAPLPIPS 2225
P +P P PV + + A R +P EP +AP + +AP P
Sbjct: 10771 PPAKVPEVPKKPV-LEEKPAVPVPER---AESPPPEVYEEPEEIAPEEEIAPEEEKP--- 10823
Query: 2226 NLFVPTPDAEEPQLPDGT----------GREGPAAARGLANPEPAPEP-KVLSSAASLPG 2274
VP + EEP++P ++ P + A P PEP KV+ P
Sbjct: 10824 ---VPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPR 10880
Query: 2275 SELPSSRP 2282
P P
Sbjct: 10881 PPPPPPAP 10888
Score = 55.5 bits (132), Expect = 6e-07
Identities = 94/420 (22%), Positives = 147/420 (35%), Gaps = 100/420 (23%)
Query: 1899 ALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPS--APQT 1956
A+P + P E+ + L +P A + P PA P+ + P + +P AP
Sbjct: 10653 AIPPKPESPPPEVFEEPEEVALEEPPAEVVEEP---EPAAPPQVTVPPKKPVPEKKAPAV 10709
Query: 1957 LPDGPLASPARVPMFP--------VPL--------PPGPLEPGPGCVTPGPALGFLEPSG 2000
+ P P +VP P VPL PP + P V P + P
Sbjct: 10710 VAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAV--PKK 10767
Query: 2001 PGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVP 2060
P +PP P ++ +L+E + VP + E+ EE P P
Sbjct: 10768 PEVPPAKVPEVPKKPVLEEKPA-----VPVPERAESPPPEVYEE----------PEEIAP 10812
Query: 2061 DSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKE--PKKGESWFFRWLPGKKK 2118
+ E P ++ P+ ++ E + P A +E K+ P+K +P KK
Sbjct: 10813 EEEIAPEEEK--------PVPVAEEEEPEVPPPAVPEEPKKIIPEKK-------VPVIKK 10857
Query: 2119 TEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPT-------------------- 2158
EA P + V + +P+ + + PPPPP
Sbjct: 10858 PEAPPPKEPEPEKV----------IEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKK 10907
Query: 2159 -----SMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYV--DVLNPSGTQRSEPALAP 2211
+P+ V+ P +PG + R + V VL + EP + P
Sbjct: 10908 VPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKR-PEEEEPKVEP 10966
Query: 2212 ADFVA---PLAPLPIP----SNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPK 2264
P P P P + VPT E ++P+ T A L PEP P+P+
Sbjct: 10967 KKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPE 11026
Score = 48.1 bits (113), Expect = 1e-04
Identities = 73/317 (23%), Positives = 110/317 (34%), Gaps = 43/317 (13%)
Query: 1936 PAPSPEHSSPSVRLLPSAPQTLPDGP--LASPARVPMFPVPLPPGPLEPGPGCVTPGPAL 1993
P P E P V P +P+ P + +VP+ P P P EP P V P
Sbjct: 10823 PVPVAEEEEPEV-----PPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPK- 10876
Query: 1994 GFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQ--EAPVGNSLSELSEENFDGKFA 2051
L+P P PP PP ++ + + + ++ VP+ + P L+ L + K
Sbjct: 10877 --LKPRPPP-PPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVR 10933
Query: 2052 NLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFR 2111
L P R E S + P P E K+ + K EP +
Sbjct: 10934 KLLPERKPEPKEEVV----LKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 10989
Query: 2112 WLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPAL 2171
+P K E +P+ + + L PE + K T P V+ P +
Sbjct: 10990 EVPTVTKRERKIPEPTKVPEI-----KPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPI 11044
Query: 2172 PGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPT 2231
P PV + A +A + P G + P P+ PI
Sbjct: 11045 AAPVTVPV---VGKKAEAKAPKEEAAKPKGPIKGVPKKTPS---------PI-------- 11084
Query: 2232 PDAEEPQLPDGTGREGP 2248
+AE +L G+G E P
Sbjct: 11085 -EAERRKLRPGSGGEKP 11100
Score = 43.5 bits (101), Expect = 0.002
Identities = 87/367 (23%), Positives = 126/367 (34%), Gaps = 75/367 (20%)
Query: 1940 PEHSSPSVRLLPSAPQTLPDGPLASPARV-----PMFPVPLP-PGPLEPGPGCVTPGPAL 1993
PE P V+ +P P +P P A PA+V P VP+P P L+P P V P
Sbjct: 9789 PEKPIP-VKPVPEEP--VPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKK 9845
Query: 1994 GFLEPSGPGL----------PPGVPPLQERRHLLQEA-----RSPDPGIVPQEAP----- 2033
F E + P P++ +R + +E + P + E P
Sbjct: 9846 VFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEP 9905
Query: 2034 ------------VGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLS 2081
V L E EE + +T VP P +
Sbjct: 9906 EEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKV-----------PEVP 9954
Query: 2082 LSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWV 2141
P PE K+P KK+ P K +P K P++K ++ KK +
Sbjct: 9955 RKPVPEEKKPVPVPKKKEAPPAKVPE-----VPKK-------PEEKVPVLI--PKKEKPP 10000
Query: 2142 NLNEPEEEKKAPPPP--PTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNP 2199
PE KK P P +PK V+A P +P P PV ++ + V+ P
Sbjct: 10001 PAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVP--EKKVPVPAPKKVEA-PP 10057
Query: 2200 SGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEP 2259
+ L P + P P+P + P P + + P P L E
Sbjct: 10058 AKVPEVPKKLIPEE----KKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEI 10113
Query: 2260 APEPKVL 2266
PE +VL
Sbjct: 10114 VPEEEVL 10120
Score = 43.1 bits (100), Expect = 0.003
Identities = 76/334 (22%), Positives = 124/334 (37%), Gaps = 62/334 (18%)
Query: 1969 PMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIV 2028
P P+P+ P P EP P P L+ + P VP + + P P V
Sbjct: 9789 PEKPIPVKPVPEEPVP-TKPKAPPAKVLKKAVPEEKVPVP--------IPKKLKPPPPKV 9839
Query: 2029 PQ------EAPVGNSLSELSEENFDGKFAN--LTPSRTVPDSEAPPGWDRADSGPTQPPL 2080
P+ E + S+++ +E A + P R V + + P PP+
Sbjct: 9840 PEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVP-----VPRKEVAPPV 9894
Query: 2081 SLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQW 2140
+ P+ P + A +E E ++ E Y+ ++ + + +E+
Sbjct: 9895 RVPEVPKELEPEEVAFEEEVVTHVEEYLV-------EEEEEYIHEE--EEFITEEEVVPV 9945
Query: 2141 VNLNEPEEEKKAPP--PPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLN 2198
+ + PE +K P P +PK +A P +P P P V VL
Sbjct: 9946 IPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKP------------EEKVPVLI 9993
Query: 2199 PSGTQRSEPALAPADFVAPL----APLPIPSNLFVPTPDAEEPQLPDGTGREG----PAA 2250
P ++ PA P P+ P+P+P V P A+ P++P E PA
Sbjct: 9994 PK-KEKPPPAKVPEVPKKPVPEEKVPVPVPKK--VEAPPAKVPEVPKKPVPEKKVPVPAP 10050
Query: 2251 ARGLANPEPAPE-PKVLSSAASLPGSELPSSRPE 2283
+ A P PE PK L +P + P+ P+
Sbjct: 10051 KKVEAPPAKVPEVPKKL-----IPEEKKPTPVPK 10079
Score = 39.7 bits (91), Expect = 0.035
Identities = 68/288 (23%), Positives = 107/288 (37%), Gaps = 56/288 (19%)
Query: 1935 VPAPSPEHSSPSVRLLPSAPQT-LPDG--PLASPARVPMFPVPLPPGPLEPGPGCVTPGP 1991
VP P+ P +P P+ +P+ P+ P +V P +P P +P P P P
Sbjct: 9989 VPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVP 10048
Query: 1992 ALGFLE------PSGP------------------GLPPGVPPL-----------QERRHL 2016
A +E P P PP VP QE L
Sbjct: 10049 APKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVL 10108
Query: 2017 LQEARSPDPGIVPQEAPVGNSLSEL--SEENFDGKFANLTP--SRTVPDSEAPPGWD--- 2069
+E P+ ++P+E V E+ EE + + P P+ E P +
Sbjct: 10109 FEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFV 10168
Query: 2070 -RADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKN 2128
+ P P PAP + + +K+ PKK E+ P K E ++
Sbjct: 10169 PEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEA------PPAKVPEVPKKVEEK 10222
Query: 2129 KSIVWDEKKNQWVNL-NEPEEE---KKAPPPPPTSMPKTVQAAPPALP 2172
+ I+ E++ V + EPEEE ++ P P S+ + + APP +P
Sbjct: 10223 RIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVP 10270
Score = 39.7 bits (91), Expect = 0.035
Identities = 71/334 (21%), Positives = 108/334 (32%), Gaps = 40/334 (11%)
Query: 3 PPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAA---VAPTTCPLQPVTDPFAFSR 59
PP + VP PPA P A P A P P +P P
Sbjct: 10500 PPKEVVPEKKVPVPPAKKPE----APPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPE 10555
Query: 60 QALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRA 119
+ P ++ PP + P P + P +VP + + P +P P+ P A
Sbjct: 10556 VPKAAVPEKKVPEAIPPKPESPPPE-VPEAPKEVVP--EKKVPAAPPKKPEVTPVKVPEA 10612
Query: 120 HASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNM 179
P PP + EV P+ PEV + +P P
Sbjct: 10613 PKEVVPEKKVPVPPP-----KKPEVPPTKVPEVPKVAVPEKKVPEAIPP----------- 10656
Query: 180 PGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPS 239
++P V +L +P ++ + P PQ + + P PE P+
Sbjct: 10657 -------KPESPPPEVFEEPEEVALEEPPAEVVEEPEPA-APPQVTVPPKKPVPEKKAPA 10708
Query: 240 GVPCATSVPHFPTPSILHQGPGHEQHSPLVAP--PAALPSDGRDEVSHLQSGSHLANNSD 297
V +P P + + E+ PLV P P A P+ + + +A
Sbjct: 10709 VVAKKPELPPVKVPEVPKE-VVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKK 10767
Query: 298 PESTFRQNPRIVNHWASPELRQNPGVKNEHRPAS 331
PE + P + P L + P V R S
Sbjct: 10768 PEVPPAKVPEVPK---KPVLEEKPAVPVPERAES 10798
Score = 39.3 bits (90), Expect = 0.046
Identities = 52/197 (26%), Positives = 68/197 (34%), Gaps = 28/197 (14%)
Query: 2086 PETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPD--DKNKSIVWDEKKNQWVNL 2143
P TK P KE KK +P KK EA P + K +V ++K
Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVP------VPPAKKPEAPPPKVPEAPKEVVPEKKV------ 10538
Query: 2144 NEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRA--RYVDVLNPSG 2201
P K P PPT +P+ +AA P P P S A V
Sbjct: 10539 --PVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPA 10596
Query: 2202 TQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAP 2261
+P + P P AP + VP P ++P++P E P A P
Sbjct: 10597 APPKKPEVTPVK--VPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVA--------VP 10646
Query: 2262 EPKVLSSAASLPGSELP 2278
E KV + P S P
Sbjct: 10647 EKKVPEAIPPKPESPPP 10663
Score = 37.4 bits (85), Expect = 0.18
Identities = 100/468 (21%), Positives = 158/468 (33%), Gaps = 101/468 (21%)
Query: 1860 PQLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALP---QQCPGTPSSEMEQLD 1916
P+ + PEEE + L + E + E V ++ +P ++ P P E +
Sbjct: 10115 PEEEVLPEEEEV--------LPEEEEVLPEEEEVLPEEEEIPPEEEEVP--PEEEYVPEE 10164
Query: 1917 RPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLP 1976
+ + L P + VPAP PE + + +P A PA+VP P +
Sbjct: 10165 EEFVPEEEVLPEVKPKVPVPAPVPEIK----KKVTEKKVVIPKKEEAPPAKVPEVPKKVE 10220
Query: 1977 ------PGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQ 2030
P E P VT P EP P PP E + R P+ ++ +
Sbjct: 10221 EKRIILPKEEEVLPVEVTEEPEE---EPISEEEIPEEPPSIEEVEEVAPPRVPE--VIKK 10275
Query: 2031 EAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKR 2090
P + E K S+ +P+ + P + ++ P + P PE K
Sbjct: 10276 AVPEAPTPVPKKVEAPPAKV-----SKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKV 10330
Query: 2091 PGQAAKKETKEPKKGESW--------FFRWLPGKKKTEAYLPDDKNKSIVWDE------- 2135
KKE P KG + F + + K++ E + + + + I +E
Sbjct: 10331 --LVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEE 10388
Query: 2136 ----------------------------KKNQWVNLNEPEE-----EKKAPPPPPTSMPK 2162
K ++ + + E EE + KAPP P K
Sbjct: 10389 YFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEK 10448
Query: 2163 TVQAAPPALPGPPGAPVNMYSRRAAGTRARYVD---VLNPSGTQRSEPALAPADFVAPLA 2219
+ PP P P + R+ + V V+ EP + P L
Sbjct: 10449 II---PPKKP-----PTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLP 10500
Query: 2220 PLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPE---PAPEPK 2264
P + VP P A++P+ P E P PE P P PK
Sbjct: 10501 PKEVVPEKKVPVPPAKKPEAPPPKVPEAPKE----VVPEKKVPVPPPK 10544
Score = 36.6 bits (83), Expect = 0.30
Identities = 54/220 (24%), Positives = 81/220 (36%), Gaps = 43/220 (19%)
Query: 1945 PSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLP 2004
P V LP P P+ P +V +P P +P P P P + P P
Sbjct: 9286 PKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVP----VPKKEPAAP 9341
Query: 2005 PGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEA 2064
P VP + ++ + E + P P +EAP + E+ + + + R E+
Sbjct: 9342 PKVPEVPKKP--VPEEKIPVPVAKKKEAPPA-KVPEVQKGVVTEEKITIVTQR----EES 9394
Query: 2065 PPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLP 2124
PP P P + PE ++P ++E P K + LP K +P
Sbjct: 9395 PP--------PAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPA-----LPKKP-----VP 9436
Query: 2125 DDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTV 2164
++K V + P KKAPPP KTV
Sbjct: 9437 EEK-------------VAVPVP-VAKKAPPPRAEVSKKTV 9462
Score = 35.8 bits (81), Expect = 0.51
Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 13/113 (11%)
Query: 1052 PGLERAQQELVPPQQQASPP------------QLPKAMFSELSNPESLPAQGQAQNSAQS 1099
P + A +E+VP ++ PP ++PKA E PE++P + ++ +
Sbjct: 10523 PKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP-PPEV 10581
Query: 1100 PASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPP 1152
P + V +++P PP+ V+ V V E+ P P P PP
Sbjct: 10582 PEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPP 10634
Score = 35.4 bits (80), Expect = 0.67
Identities = 45/177 (25%), Positives = 64/177 (36%), Gaps = 22/177 (12%)
Query: 2004 PPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSE 2063
PP VP L E+ + A P P V AP ++ E P + VP+ +
Sbjct: 9285 PPKVPELPEKPAPEEVAPVPIPKKVEPPAP------KVPE----------VPKKPVPEEK 9328
Query: 2064 APPGWDRADSG--PTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEA 2121
P + + P P + P PE K P AKK+ P K + +K T
Sbjct: 9329 KPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIV 9388
Query: 2122 YLPDDKNKSIVWDEKKNQWVNLNEP----EEEKKAPPPPPTSMPKTVQAAPPALPGP 2174
++ V + K + +P EEE PP P K V A+P P
Sbjct: 9389 TQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVP 9445
Score = 35.4 bits (80), Expect = 0.67
Identities = 23/103 (22%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1055 ERAQQELVPPQQQASPPQLPKA---MFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQ 1111
E+ E +PP+ ++ PP++P+A + E P + P + + + P + V ++
Sbjct: 10563 EKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEV-TPVKVPEAPKEVVPEKK 10621
Query: 1112 LPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQ 1154
+P PP+ V E+ P+ +P PPP+
Sbjct: 10622 VPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPE 10664
Score = 34.7 bits (78), Expect = 1.1
Identities = 77/358 (21%), Positives = 121/358 (33%), Gaps = 36/358 (10%)
Query: 1931 PLLAVPAPSP---EHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCV 1987
P P P P E +P V +P P P+ P + P P +P P +P P
Sbjct: 9297 PEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEK 9356
Query: 1988 TPGPALGFLE---PSGPGLPPGVPPLQERRHLLQEARSPDPGI-------VPQEAPVGNS 2037
P P E P + GV ++ + Q SP P + VP+E
Sbjct: 9357 IPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEER---KP 9413
Query: 2038 LSELSEENFDGKFANLTPSRTVPDSE-APPGWDRADSGPTQPPLSLSPAPETKRPGQAAK 2096
+ EE P + VP+ + A P + P + +S E KR K
Sbjct: 9414 VPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEK 9473
Query: 2097 KETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSI-VWDEKKNQWVNLNEPEEEKKAPPP 2155
P++ E R ++ +Y +++ SI V+ E++ + E E + P
Sbjct: 9474 LSFAVPQRVE--VTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEP 9531
Query: 2156 PPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFV 2215
+ + + + P ++ VL P + E P
Sbjct: 9532 EEYVVEEKLHIISKRVEAEPAEVTERQEKKI---------VLKPKIPAKIE---EPPPAK 9579
Query: 2216 APLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLP 2273
P AP I VP P ++ ++P E P PE PKV+ LP
Sbjct: 9580 VPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKK----PVPEKKVPPKVIKMEEPLP 9633
Score = 34.3 bits (77), Expect = 1.5
Identities = 36/144 (25%), Positives = 51/144 (35%), Gaps = 19/144 (13%)
Query: 2055 PSRTVPDSEAPPGWDRA--DSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRW 2112
P + P+ AP + P P + P PE K+P KKE P K +
Sbjct: 9292 PEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKP 9351
Query: 2113 LP---------GKKKTEAYLPDDKNKSIVWDEKKNQWVNLNE------PEEEKKAPPPPP 2157
+P KK+ + K +V +EK E PE KK P
Sbjct: 9352 VPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEER 9411
Query: 2158 TSMPKTVQAA--PPALPGPPGAPV 2179
+P+ + PP +P P PV
Sbjct: 9412 KPVPRKEEEVPPPPKVPALPKKPV 9435
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 65.9 bits (159), Expect = 5e-10
Identities = 120/482 (24%), Positives = 165/482 (34%), Gaps = 128/482 (26%)
Query: 1881 QQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSP 1940
++ E + K+ G ++ A+ ++ P++E E+ P P L PAPSP
Sbjct: 367 EKKEEEEKDKEGEEKEERAVAEEM--MPAAEKEEAKLPP-----------PPLTPPAPSP 413
Query: 1941 EHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSG 2000
P P T P PL P P+ P PLP P P PA E S
Sbjct: 414 PPPLP-------PPSTSPPPPLCPPPPPPVSPPPLPSPP---------PPPAQEEQEESP 457
Query: 2001 PGLPP-------GVPPLQERRHLLQEARSPDP--------------GIVPQEAPVGNSLS 2039
P + P G PPL + +EA P G P+++P S
Sbjct: 458 PPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKS 517
Query: 2040 ELSEEN---FDGKFANLTPSRTVPD-----SEAPPGWDRADSGP-------TQPPLSLSP 2084
+N F + SR + E PP + + P T PP+ P
Sbjct: 518 TTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEP 577
Query: 2085 APETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLN 2144
AP P T P LP K+++ + E +W +L
Sbjct: 578 APVPSPPRAPTPPSTPVP----------LPEKRRS------------ILREPTFRWTSLT 615
Query: 2145 EPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRAR-----------Y 2193
++ PPPPP P PPA P PP AP SRR RA Y
Sbjct: 616 -----RELPPPPPAPPP------PPA-PSPPPAPATS-SRRPLLLRAPQFTPSEAHLKIY 662
Query: 2194 VDVLNP---SGTQRSEPALAPADFVAPLAPLP----------IPSNLFVPTPDAEEPQLP 2240
VL P + EP PAD +P P P +P V T + P
Sbjct: 663 ESVLTPPPLGAPEAPEPEPPPAD-DSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSP 721
Query: 2241 DGTG--REGPAAARGLANPEPAPEPKVLSSAASLPGSEL-PSSRPEGSQGGELSRCSSMS 2297
G GP L P A + ++L A P +L P P+ E +R + +
Sbjct: 722 HGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVG 781
Query: 2298 SL 2299
SL
Sbjct: 782 SL 783
Score = 39.3 bits (90), Expect = 0.046
Identities = 62/208 (29%), Positives = 82/208 (39%), Gaps = 46/208 (22%)
Query: 1923 PGALGIANPLLAVPAPSPEHSSPSVRLLPSA-----PQTLPDG-PLASPARVPMFPVPLP 1976
PGA G+ L PAP P + S +L + + +G P+ P + P PLP
Sbjct: 2167 PGAPGV-RVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQP----PLP 2221
Query: 1977 P--GPLEPGPGCVTPGPALGFLEPSG---PGLPPGVPPL----------------QERRH 2015
P P P + PGP LG L G P PP PPL + +R
Sbjct: 2222 PTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRV 2281
Query: 2016 LLQEARSPDPGIVPQEAPVGNSLSELSEEN------FDGKFANL---TPS-RTVPDSEAP 2065
RSP P P +AP + E SE+ G F+ + TP+ R V D + P
Sbjct: 2282 STFSGRSP-PAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRP 2340
Query: 2066 --PGWDRADSGPTQPPLSLSPAPETKRP 2091
P + + GP Q L P PE P
Sbjct: 2341 GEPAGEES-PGPLQERSPLLPLPEDGPP 2367
Score = 34.3 bits (77), Expect = 1.5
Identities = 61/277 (22%), Positives = 94/277 (33%), Gaps = 27/277 (9%)
Query: 889 PTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAG 948
PT + S + ++ Q P S S V P + + P +P + P +
Sbjct: 511 PTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTS 570
Query: 949 SALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNV 1008
+P PA S P T VP K S +E T+ T P
Sbjct: 571 PPVP---QEPAPVPSPPRAPTPPSTPVPLPEK-RRSILREPTFRWTSLTRELPPPPPAPP 626
Query: 1009 YNPSHSD----SLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPP 1064
P+ S + +S++ + Q P +L + +T G P E + E P
Sbjct: 627 PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAP--EAPEPEPPPA 684
Query: 1065 QQQASPPQLPKAM--FSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPR---PPQS 1119
+ P+ P+A+ + LS P P + SP + G Q + P Q+
Sbjct: 685 DDSPAEPE-PRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQA 743
Query: 1120 SSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDL 1156
L+ Q P P P L P P PQ +
Sbjct: 744 LQTQLLP-----------QALPPPQPQLQPPPSPQQM 769
Score = 33.9 bits (76), Expect = 1.9
Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 14/93 (15%)
Query: 1063 PPQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSV 1122
PP SPP LP +P PAQ + Q + P + PP P +
Sbjct: 431 PPPPPVSPPPLP--------SPPPPPAQ-EEQEESPPPVVPATCSRKRGRPPLTPSQRAE 481
Query: 1123 SLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQD 1155
+ + P P P P+ A G PP+D
Sbjct: 482 REAARAGPEGTSP-----PTPTPSTATGGPPED 509
Score = 32.7 bits (73), Expect = 4.3
Identities = 65/277 (23%), Positives = 88/277 (31%), Gaps = 48/277 (17%)
Query: 3 PPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQAL 62
PPP P + PPP P ++SP P CP P
Sbjct: 402 PPPPLTPPAPSPPPPLPPP-----STSP-----------PPPLCPPPP------------ 433
Query: 63 QSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHAS 122
P+ SPP PA + P +VP T +R + P P + A A
Sbjct: 434 --PPVSPPPLPSPP--PPPAQEEQEESPPPVVPATCSRKRGRPPLTP-SQRAEREAARAG 488
Query: 123 PFSGALTPSAPPGPEMNRSAEVGPSSEPEVQT-LPYLPHYI-PGVDPETSHGGHPHGNMP 180
P G P+ P E P+ P+ T L + +I P V +S
Sbjct: 489 P-EGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFM 547
Query: 181 GLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSG 240
D P + V+ P + S P +P + PV P P P P+P
Sbjct: 548 DEDPPKPPKVEVSPVLRPPITTSPP-----VPQEPAPV---PSPPRAPTPPSTPVPLPEK 599
Query: 241 VPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPS 277
P F S+ + P P PP PS
Sbjct: 600 RRSILREPTFRWTSLTRELP----PPPPAPPPPPAPS 632
Score = 32.7 bits (73), Expect = 4.3
Identities = 35/154 (22%), Positives = 57/154 (37%), Gaps = 23/154 (14%)
Query: 1084 PESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQP 1143
P L A + Q SPA G+ PP + V + + + + + P +P
Sbjct: 1792 PAHLEAAEENQTIVHSPAPSSEPPGGED----PPLDTDVLVPGAPERHSPIQNLDPPLRP 1847
Query: 1144 VPALAPGPPPQDLAAYYYYRPLYD-AYQPQYSLPYPP--EPGAASLYYQDVYSLYEPRYR 1200
AP P P+ + P Y + +P + + P PG+ S + ++ +P +
Sbjct: 1848 DSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDF- 1906
Query: 1201 PYDGAASAYAQNYRYPEPERPSSRASHSSERPPP 1234
P P R S R S + RPPP
Sbjct: 1907 ---------------PAPPRRSRRPSPLAPRPPP 1925
Score = 31.6 bits (70), Expect = 9.6
Identities = 30/104 (28%), Positives = 35/104 (33%), Gaps = 8/104 (7%)
Query: 204 LPQPGLQMPGQWGPVQGGPQPSGQHRSP-CPEGPVPSGVPCATSVPHFPTPSILHQGPGH 262
LP P L P P P PS P CP P P S P P+P
Sbjct: 401 LPPPPLTPPAP-SPPPPLPPPSTSPPPPLCPPPPPP------VSPPPLPSPPPPPAQEEQ 453
Query: 263 EQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNP 306
E+ P V P GR ++ Q A + PE T P
Sbjct: 454 EESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP 497
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 65.5 bits (158), Expect = 6e-10
Identities = 106/378 (28%), Positives = 134/378 (35%), Gaps = 78/378 (20%)
Query: 1936 PAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPP---------GPLEPGPGC 1986
PAP P PS P + LP+G P P PP P P PG
Sbjct: 633 PAPQPSGGDPS----PPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPG- 687
Query: 1987 VTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEA--PVGNSLSELSEE 2044
PG F +GP P PP +RR P G EA PVG++L
Sbjct: 688 PPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTL------ 741
Query: 2045 NFDGKFANLTPS-------RTVPDSEAPP--GWDRADSGPTQPPLSLSPAPETKRPGQAA 2095
G +A LT RT P P G R+ S + P P KR +
Sbjct: 742 ---GSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVS 798
Query: 2096 KKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPP 2155
+ P ES PG K+ A P + L+EP + P P
Sbjct: 799 GPSPEPPPLDES------PGPKEG-ATGPRRRT--------------LSEPAGPSEPPGP 837
Query: 2156 PPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFV 2215
P + P + PGP G P SR ++G + + N + QR +PA P
Sbjct: 838 PAPAGPASDTEEEE--PGPEGTPP---SRGSSGEGLPFAEEGNLTIKQRPKPAGPPP--- 889
Query: 2216 APLAPLPIPSNL-FVPTPDAEEPQLPDGTGRE---------GPAAAR-GLANPEPAPEPK 2264
P+P L F T + P RE G A+A G A P P+P P
Sbjct: 890 ---RETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPG 946
Query: 2265 VLSSAASLPGSELPSSRP 2282
A+SLP E PSS P
Sbjct: 947 ESPPASSLPQPE-PSSLP 963
Score = 55.1 bits (131), Expect = 8e-07
Identities = 104/402 (25%), Positives = 140/402 (34%), Gaps = 66/402 (16%)
Query: 1917 RPGLSQPGALGIANPLLAVPAPS---PEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPV 1973
RPG S AL +P + P P+ P S ++R P P L+S + P
Sbjct: 750 RPGRS---ALVRTSPSVT-PTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSG----PS 801
Query: 1974 PLPPGPLE--PGPGCVTPGPALGFL-EPSGPGLPPGVPPLQERRHLLQEARSPDP-GIVP 2029
P PP PL+ PGP GP L EP+GP PPG PP E P P G P
Sbjct: 802 PEPP-PLDESPGPKEGATGPRRRTLSEPAGPSEPPG-PPAPAGPASDTEEEEPGPEGTPP 859
Query: 2030 QEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWD----RADSGPTQP------P 2079
G L E N K ++ PPG D +D+ +P P
Sbjct: 860 SRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREP 919
Query: 2080 LS---LSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEK 2136
L L+ + PG AA + P G+ + LP + S+
Sbjct: 920 LQTALLAFGVASATPGPAAPLPSPTP------------GESPPASSLPQPEPSSLPAQGV 967
Query: 2137 KNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDV 2196
P + PP P + + + PP AP + AGT + V V
Sbjct: 968 PTPLAP--SPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSV 1025
Query: 2197 LNPSGTQR--SEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGL 2254
+ TQ S P LAP L P P+P P P+ TG GP A+
Sbjct: 1026 ---ACTQLAFSGPKLAPR-----LGPRPVP------------PPRPESTGTVGPGQAQQR 1065
Query: 2255 ANPEPAPEPKVLSSAASLPGSELPSSRPEGSQGGELSRCSSM 2296
+ L +A G++ P S L S+M
Sbjct: 1066 LEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTM 1107
Score = 39.3 bits (90), Expect = 0.046
Identities = 110/479 (22%), Positives = 155/479 (32%), Gaps = 65/479 (13%)
Query: 719 ESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQP---PVVQPPEEAMSGQQSRNPSS 775
E PAT A L F G+ L +P A P+P P + P + G +SR
Sbjct: 573 EGPAT---AGPRLLTFQGSEL-SPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGH 628
Query: 776 A----APVQSRGGIGAS------ENLENPPKMGEEEALQSQASSGYASLL--SSPPTESL 823
+ AP S G E E PPK+ +L Q Y + SP + +
Sbjct: 629 SQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCS--SLPGQGPPPYVFMYPQGSPSSPAP 686
Query: 824 QNPP-------VLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALG 876
PP L P + +P S SLS GD + +G
Sbjct: 687 GPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTE--------GDAEGEAEGPVG 738
Query: 877 GDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPEN 936
G +L+ P S L + PS +G+ S+ + + A PP P +
Sbjct: 739 STLGSYATLTRRPGRSALVRTSPSVTPTP--ARGTPRSQSFALR-ARRKGPPPPPPKRLS 795
Query: 937 LVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANH---SSHQEDTYGA 993
V + PG G L PA G P G A S +E+ G
Sbjct: 796 SVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPA-GPSEPPGPPAPAGPASDTEEEEPGP 854
Query: 994 LDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQP- 1052
SR + + ++ + A P + P P LD F + + +P
Sbjct: 855 EGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLD-FNLTESDTVKRRPK 913
Query: 1053 --------------GLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQ 1098
G+ A P +P + P A P SLPAQG A
Sbjct: 914 CREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAP 973
Query: 1099 SPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLA 1157
SPA +PP P S S +G+ P+ VP P P +A
Sbjct: 974 SPA------MQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVA 1026
Score = 37.7 bits (86), Expect = 0.13
Identities = 62/245 (25%), Positives = 88/245 (35%), Gaps = 29/245 (11%)
Query: 6 QTVPSGMAGPPPAGNPRSVFWA--------SSPYRRRANNNAAVAPTTCPLQPVTDPFAF 57
+T PS + P G PRS +A P +R ++ + +P PL P
Sbjct: 758 RTSPS-VTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEG 816
Query: 58 S---RQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPL 114
+ R+ S P G S PP GPA + PG S +G G L
Sbjct: 817 ATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNL 876
Query: 115 T---QPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSH 171
T +P+ P TP PPG + N + P+ + L + ++
Sbjct: 877 TIKQRPKPAGPP--PRETP-VPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASA- 932
Query: 172 GGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSP 231
PG PL +P G PA+S P+P +P Q P P P+ Q P
Sbjct: 933 -------TPGPAAPL--PSPTPGESPPASSLPQPEPS-SLPAQGVPTPLAPSPAMQPPVP 982
Query: 232 CPEGP 236
GP
Sbjct: 983 PCPGP 987
Score = 37.4 bits (85), Expect = 0.18
Identities = 60/221 (27%), Positives = 79/221 (35%), Gaps = 33/221 (14%)
Query: 63 QSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHAS 122
QS L + K PP P P S G P D S GP E GP + R +
Sbjct: 775 QSFALRARRKGPPP----PPPKRLSSVSGPS-PEPPPLDESPGPKEGATGP--RRRTLSE 827
Query: 123 PFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGL 182
P PS PPGP A GP+S+ E + PG + G +P
Sbjct: 828 PAG----PSEPPGPP----APAGPASDTEEEE--------PGPEGTPPSRGSSGEGLPFA 871
Query: 183 DRP--LSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSG 240
+ +Q P P +P P + + +P + R P + G
Sbjct: 872 EEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKR---RPKCREREPLQTALLAFG 928
Query: 241 VPCATSVPHFPTPSILHQGPGHE-QHSPLVAP-PAALPSDG 279
V AT P P PS PG S L P P++LP+ G
Sbjct: 929 VASATPGPAAPLPS---PTPGESPPASSLPQPEPSSLPAQG 966
Score = 37.0 bits (84), Expect = 0.23
Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 5/102 (4%)
Query: 180 PGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQW-GPVQGGPQPSGQHRSPCPEGPVP 238
P L ++ P + PA SPS G + G Q PQPSG SP E +P
Sbjct: 592 PELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLP 651
Query: 239 SGV----PCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALP 276
G +S+P P + P SP PP P
Sbjct: 652 EGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAP 693
Score = 36.6 bits (83), Expect = 0.30
Identities = 82/336 (24%), Positives = 116/336 (34%), Gaps = 42/336 (12%)
Query: 2006 GVPPLQE-RRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEA 2064
GV L E RR LLQ + G + P ++ L EN +G T SE
Sbjct: 533 GVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGL--ENGEGPATAGPRLLTFQGSEL 590
Query: 2065 PPGWDRADSGPTQPPLSLSPA---------PETKRPGQAAKKETKEPKKGESWFFRWLPG 2115
P A +G PL L PA ++ G + ++ +P G+
Sbjct: 591 SPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDP-------- 642
Query: 2116 KKKTEAYLPDDKNK-----SIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQ--AAP 2168
E LP+ + S + + +V + P PP P A P
Sbjct: 643 SPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGP 702
Query: 2169 PALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLF 2228
PA P P P +R + + +R + + P + A L P S L
Sbjct: 703 PATPPDPPRP-----KRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSAL- 756
Query: 2229 VPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELP--SSRPEGSQ 2286
V T + P GT R A R P P PK LSS + P E P P +
Sbjct: 757 VRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSG-PSPEPPPLDESPGPKE 815
Query: 2287 GGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPS 2322
G R ++S + ++ PG PA GP S
Sbjct: 816 GATGPRRRTLSEPAGP-----SEPPGP-PAPAGPAS 845
Score = 35.0 bits (79), Expect = 0.87
Identities = 56/221 (25%), Positives = 71/221 (32%), Gaps = 22/221 (9%)
Query: 1031 GPGAPNLDRFYQQVTKDAQGQ---PGLERAQQELVPPQQQASPPQLPKAMFSELSNPESL 1087
G G P Y Q + + PG A L P P PK LS P
Sbjct: 666 GQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPG-- 723
Query: 1088 PAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPAL 1147
P +G A+ A+ P L + L RP +S+ V S + A + + + A
Sbjct: 724 PTEGDAEGEAEGPVGSTL-GSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRAR 782
Query: 1148 APGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAAS 1207
GPPP P P P E GA PR R A
Sbjct: 783 RKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKE-GATG-----------PRRRTLSEPAG 830
Query: 1208 AYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSG 1248
P P P+ AS + E P +G P SS G
Sbjct: 831 PSEP----PGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEG 867
Score = 32.7 bits (73), Expect = 4.3
Identities = 56/236 (23%), Positives = 74/236 (31%), Gaps = 53/236 (22%)
Query: 5 PQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQS 64
PQ PS A PP G P + + + P P T P DP R++
Sbjct: 677 PQGSPSSPAPGPPPGAPWAFSYLAGP------------PATPP-----DPPRPKRRSHSL 719
Query: 65 TPLGSSSKSSPPVLQGPAPAGFSQHPGLLV-PHTHARDSSQGPCEPLPGPLTQPRAHASP 123
+ G + + +GP + + L P A + P P T PR+ +
Sbjct: 720 SRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGT-PRSQSFA 778
Query: 124 FSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLD 183
A PP P S+ GPS EP P P G
Sbjct: 779 LR-ARRKGPPPPPPKRLSSVSGPSPEP----------------PPLDESPGPKEGATG-- 819
Query: 184 RPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPS 239
P ++ A PS P PG P GP + P PEG PS
Sbjct: 820 -------PRRRTLSEPAGPSEP------PGP--PAPAGPASDTEEEEPGPEGTPPS 860
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 65.5 bits (158), Expect = 6e-10
Identities = 106/378 (28%), Positives = 134/378 (35%), Gaps = 78/378 (20%)
Query: 1936 PAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPP---------GPLEPGPGC 1986
PAP P PS P + LP+G P P PP P P PG
Sbjct: 715 PAPQPSGGDPS----PPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPG- 769
Query: 1987 VTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEA--PVGNSLSELSEE 2044
PG F +GP P PP +RR P G EA PVG++L
Sbjct: 770 PPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTL------ 823
Query: 2045 NFDGKFANLTPS-------RTVPDSEAPP--GWDRADSGPTQPPLSLSPAPETKRPGQAA 2095
G +A LT RT P P G R+ S + P P KR +
Sbjct: 824 ---GSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVS 880
Query: 2096 KKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPP 2155
+ P ES PG K+ A P + L+EP + P P
Sbjct: 881 GPSPEPPPLDES------PGPKEG-ATGPRRRT--------------LSEPAGPSEPPGP 919
Query: 2156 PPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFV 2215
P + P + PGP G P SR ++G + + N + QR +PA P
Sbjct: 920 PAPAGPASDTEEEE--PGPEGTPP---SRGSSGEGLPFAEEGNLTIKQRPKPAGPPP--- 971
Query: 2216 APLAPLPIPSNL-FVPTPDAEEPQLPDGTGRE---------GPAAAR-GLANPEPAPEPK 2264
P+P L F T + P RE G A+A G A P P+P P
Sbjct: 972 ---RETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPG 1028
Query: 2265 VLSSAASLPGSELPSSRP 2282
A+SLP E PSS P
Sbjct: 1029 ESPPASSLPQPE-PSSLP 1045
Score = 55.1 bits (131), Expect = 8e-07
Identities = 104/402 (25%), Positives = 140/402 (34%), Gaps = 66/402 (16%)
Query: 1917 RPGLSQPGALGIANPLLAVPAPS---PEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPV 1973
RPG S AL +P + P P+ P S ++R P P L+S + P
Sbjct: 832 RPGRS---ALVRTSPSVT-PTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSG----PS 883
Query: 1974 PLPPGPLE--PGPGCVTPGPALGFL-EPSGPGLPPGVPPLQERRHLLQEARSPDP-GIVP 2029
P PP PL+ PGP GP L EP+GP PPG PP E P P G P
Sbjct: 884 PEPP-PLDESPGPKEGATGPRRRTLSEPAGPSEPPG-PPAPAGPASDTEEEEPGPEGTPP 941
Query: 2030 QEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWD----RADSGPTQP------P 2079
G L E N K ++ PPG D +D+ +P P
Sbjct: 942 SRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREP 1001
Query: 2080 LS---LSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEK 2136
L L+ + PG AA + P G+ + LP + S+
Sbjct: 1002 LQTALLAFGVASATPGPAAPLPSPTP------------GESPPASSLPQPEPSSLPAQGV 1049
Query: 2137 KNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDV 2196
P + PP P + + + PP AP + AGT + V V
Sbjct: 1050 PTPLAP--SPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSV 1107
Query: 2197 LNPSGTQR--SEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGL 2254
+ TQ S P LAP L P P+P P P+ TG GP A+
Sbjct: 1108 ---ACTQLAFSGPKLAPR-----LGPRPVP------------PPRPESTGTVGPGQAQQR 1147
Query: 2255 ANPEPAPEPKVLSSAASLPGSELPSSRPEGSQGGELSRCSSM 2296
+ L +A G++ P S L S+M
Sbjct: 1148 LEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTM 1189
Score = 39.3 bits (90), Expect = 0.046
Identities = 110/479 (22%), Positives = 155/479 (32%), Gaps = 65/479 (13%)
Query: 719 ESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQP---PVVQPPEEAMSGQQSRNPSS 775
E PAT A L F G+ L +P A P+P P + P + G +SR
Sbjct: 655 EGPAT---AGPRLLTFQGSEL-SPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGH 710
Query: 776 A----APVQSRGGIGAS------ENLENPPKMGEEEALQSQASSGYASLL--SSPPTESL 823
+ AP S G E E PPK+ +L Q Y + SP + +
Sbjct: 711 SQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCS--SLPGQGPPPYVFMYPQGSPSSPAP 768
Query: 824 QNPP-------VLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALG 876
PP L P + +P S SLS GD + +G
Sbjct: 769 GPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTE--------GDAEGEAEGPVG 820
Query: 877 GDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPEN 936
G +L+ P S L + PS +G+ S+ + + A PP P +
Sbjct: 821 STLGSYATLTRRPGRSALVRTSPSVTPTP--ARGTPRSQSFALR-ARRKGPPPPPPKRLS 877
Query: 937 LVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANH---SSHQEDTYGA 993
V + PG G L PA G P G A S +E+ G
Sbjct: 878 SVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPA-GPSEPPGPPAPAGPASDTEEEEPGP 936
Query: 994 LDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQP- 1052
SR + + ++ + A P + P P LD F + + +P
Sbjct: 937 EGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLD-FNLTESDTVKRRPK 995
Query: 1053 --------------GLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQ 1098
G+ A P +P + P A P SLPAQG A
Sbjct: 996 CREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAP 1055
Query: 1099 SPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLA 1157
SPA +PP P S S +G+ P+ VP P P +A
Sbjct: 1056 SPA------MQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVA 1108
Score = 37.7 bits (86), Expect = 0.13
Identities = 62/245 (25%), Positives = 88/245 (35%), Gaps = 29/245 (11%)
Query: 6 QTVPSGMAGPPPAGNPRSVFWA--------SSPYRRRANNNAAVAPTTCPLQPVTDPFAF 57
+T PS + P G PRS +A P +R ++ + +P PL P
Sbjct: 840 RTSPS-VTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEG 898
Query: 58 S---RQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPL 114
+ R+ S P G S PP GPA + PG S +G G L
Sbjct: 899 ATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNL 958
Query: 115 T---QPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSH 171
T +P+ P TP PPG + N + P+ + L + ++
Sbjct: 959 TIKQRPKPAGPP--PRETP-VPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASA- 1014
Query: 172 GGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSP 231
PG PL +P G PA+S P+P +P Q P P P+ Q P
Sbjct: 1015 -------TPGPAAPL--PSPTPGESPPASSLPQPEPS-SLPAQGVPTPLAPSPAMQPPVP 1064
Query: 232 CPEGP 236
GP
Sbjct: 1065 PCPGP 1069
Score = 37.4 bits (85), Expect = 0.18
Identities = 60/221 (27%), Positives = 79/221 (35%), Gaps = 33/221 (14%)
Query: 63 QSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHAS 122
QS L + K PP P P S G P D S GP E GP + R +
Sbjct: 857 QSFALRARRKGPPP----PPPKRLSSVSGPS-PEPPPLDESPGPKEGATGP--RRRTLSE 909
Query: 123 PFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGL 182
P PS PPGP A GP+S+ E + PG + G +P
Sbjct: 910 PAG----PSEPPGPP----APAGPASDTEEEE--------PGPEGTPPSRGSSGEGLPFA 953
Query: 183 DRP--LSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSG 240
+ +Q P P +P P + + +P + R P + G
Sbjct: 954 EEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKR---RPKCREREPLQTALLAFG 1010
Query: 241 VPCATSVPHFPTPSILHQGPGHE-QHSPLVAP-PAALPSDG 279
V AT P P PS PG S L P P++LP+ G
Sbjct: 1011 VASATPGPAAPLPS---PTPGESPPASSLPQPEPSSLPAQG 1048
Score = 37.0 bits (84), Expect = 0.23
Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 5/102 (4%)
Query: 180 PGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQW-GPVQGGPQPSGQHRSPCPEGPVP 238
P L ++ P + PA SPS G + G Q PQPSG SP E +P
Sbjct: 674 PELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLP 733
Query: 239 SGV----PCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALP 276
G +S+P P + P SP PP P
Sbjct: 734 EGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAP 775
Score = 36.6 bits (83), Expect = 0.30
Identities = 82/336 (24%), Positives = 116/336 (34%), Gaps = 42/336 (12%)
Query: 2006 GVPPLQE-RRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEA 2064
GV L E RR LLQ + G + P ++ L EN +G T SE
Sbjct: 615 GVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGL--ENGEGPATAGPRLLTFQGSEL 672
Query: 2065 PPGWDRADSGPTQPPLSLSPA---------PETKRPGQAAKKETKEPKKGESWFFRWLPG 2115
P A +G PL L PA ++ G + ++ +P G+
Sbjct: 673 SPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDP-------- 724
Query: 2116 KKKTEAYLPDDKNK-----SIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQ--AAP 2168
E LP+ + S + + +V + P PP P A P
Sbjct: 725 SPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGP 784
Query: 2169 PALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLF 2228
PA P P P +R + + +R + + P + A L P S L
Sbjct: 785 PATPPDPPRP-----KRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSAL- 838
Query: 2229 VPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELP--SSRPEGSQ 2286
V T + P GT R A R P P PK LSS + P E P P +
Sbjct: 839 VRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSG-PSPEPPPLDESPGPKE 897
Query: 2287 GGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPS 2322
G R ++S + ++ PG PA GP S
Sbjct: 898 GATGPRRRTLSEPAGP-----SEPPGP-PAPAGPAS 927
Score = 35.0 bits (79), Expect = 0.87
Identities = 56/221 (25%), Positives = 71/221 (32%), Gaps = 22/221 (9%)
Query: 1031 GPGAPNLDRFYQQVTKDAQGQ---PGLERAQQELVPPQQQASPPQLPKAMFSELSNPESL 1087
G G P Y Q + + PG A L P P PK LS P
Sbjct: 748 GQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPG-- 805
Query: 1088 PAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPAL 1147
P +G A+ A+ P L + L RP +S+ V S + A + + + A
Sbjct: 806 PTEGDAEGEAEGPVGSTL-GSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRAR 864
Query: 1148 APGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAAS 1207
GPPP P P P E GA PR R A
Sbjct: 865 RKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKE-GATG-----------PRRRTLSEPAG 912
Query: 1208 AYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSG 1248
P P P+ AS + E P +G P SS G
Sbjct: 913 PSEP----PGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEG 949
Score = 32.7 bits (73), Expect = 4.3
Identities = 56/236 (23%), Positives = 74/236 (31%), Gaps = 53/236 (22%)
Query: 5 PQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQS 64
PQ PS A PP G P + + + P P T P DP R++
Sbjct: 759 PQGSPSSPAPGPPPGAPWAFSYLAGP------------PATPP-----DPPRPKRRSHSL 801
Query: 65 TPLGSSSKSSPPVLQGPAPAGFSQHPGLLV-PHTHARDSSQGPCEPLPGPLTQPRAHASP 123
+ G + + +GP + + L P A + P P T PR+ +
Sbjct: 802 SRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGT-PRSQSFA 860
Query: 124 FSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLD 183
A PP P S+ GPS EP P P G
Sbjct: 861 LR-ARRKGPPPPPPKRLSSVSGPSPEP----------------PPLDESPGPKEGATG-- 901
Query: 184 RPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPS 239
P ++ A PS P PG P GP + P PEG PS
Sbjct: 902 -------PRRRTLSEPAGPSEP------PGP--PAPAGPASDTEEEEPGPEGTPPS 942
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 63.2 bits (152), Expect = 3e-09
Identities = 74/261 (28%), Positives = 88/261 (33%), Gaps = 41/261 (15%)
Query: 80 GPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPG--PLTQPRAHASPFSGALTPSAPPGPE 137
GP P P + P H + P +P P P QP H P PP P
Sbjct: 48 GPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQ----QQQPPPPP 103
Query: 138 MNRSAEV---GPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPG---------LDRP 185
+ S V GP P V + P P P TS G P G+ PG P
Sbjct: 104 QDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS--GAPPGSGPGPTPTPPPAVTSAP 161
Query: 186 LSRQNP---HDGV-VTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGV 241
P GV TP + P P +PG + GP P G P GP P G
Sbjct: 162 PGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGG 221
Query: 242 PCATSVPHFPTP----------SILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSH 291
P ++ P P H P H+QH PP P GR E S
Sbjct: 222 PGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQ--GPPPGGPG-GRSEEKISDSEGF 278
Query: 292 LANNS----DPESTFRQNPRI 308
AN S E T+ Q R+
Sbjct: 279 KANLSLLRRPGEKTYTQRCRL 299
Score = 45.8 bits (107), Expect = 5e-04
Identities = 66/248 (26%), Positives = 77/248 (31%), Gaps = 82/248 (33%)
Query: 2 QPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQA 61
QPPP P PPP
Sbjct: 86 QPPPHPQPHQQQQPPP-------------------------------------------- 101
Query: 62 LQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHA 121
P SSK P V QGP PA PG+ S P P T P + A
Sbjct: 102 ----PPQDSSK--PVVAQGPGPA-----PGV---------GSAPPASSSAPPATPPTSGA 141
Query: 122 SPFSG-ALTP-------SAPPG-PEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSH- 171
P SG TP SAPPG P + P++ P+ P P +PG P
Sbjct: 142 PPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQG 201
Query: 172 ---GGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQH 228
GG G MPG +P G+ TP P P G P + G P H
Sbjct: 202 PGPGGPKGGKMPGGPKP----GGGPGLSTPGGHPKPPHRGGGEP-RGGRQHHPPYHQQHH 256
Query: 229 RSPCPEGP 236
+ P P GP
Sbjct: 257 QGPPPGGP 264
Score = 44.3 bits (103), Expect = 0.001
Identities = 43/147 (29%), Positives = 56/147 (38%), Gaps = 19/147 (12%)
Query: 2145 EPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAP-VNMYSRRAAGTRARYVDVLNPSGTQ 2203
+P ++++ PPPP S V P PG AP + + A + P T
Sbjct: 92 QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTP 151
Query: 2204 RSEPALAPADFVAPLAPLPIPSNLFVPT--PDAEEPQLPDGTGREGPAAARGLANPEPAP 2261
PA+ A P AP P P + VPT P A P P PAA P P P
Sbjct: 152 TPPPAVTSAP---PGAPPPTPPSSGVPTTPPQAGGPPPP-------PAAV-----PGPGP 196
Query: 2262 EPKVLSSAASLPGSELPSS-RPEGSQG 2287
PK G ++P +P G G
Sbjct: 197 GPKQGPGPGGPKGGKMPGGPKPGGGPG 223
Score = 40.8 bits (94), Expect = 0.016
Identities = 45/189 (23%), Positives = 62/189 (32%), Gaps = 34/189 (17%)
Query: 2146 PEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRS 2205
P + PP PP + Q PP P P P + +P Q+
Sbjct: 51 PGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQ-------------PPPHPQPHQQQ 97
Query: 2206 EPALAPADFVAPL---APLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPE 2262
+P P D P+ P P P P + P T P + G P P P
Sbjct: 98 QPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPG---PTPTPP 154
Query: 2263 PKVLSSAASL-----PGSELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAA 2317
P V S+ P S +P++ P+ GG +++ P P
Sbjct: 155 PAVTSAPPGAPPPTPPSSGVPTTPPQA--GGPPPPPAAVPGP--------GPGPKQGPGP 204
Query: 2318 GGPPSGAMP 2326
GGP G MP
Sbjct: 205 GGPKGGKMP 213
Score = 39.3 bits (90), Expect = 0.046
Identities = 34/129 (26%), Positives = 42/129 (32%), Gaps = 17/129 (13%)
Query: 1026 HPR---QSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELS 1082
HP+ Q P P D V + PG+ A PP ++PP P
Sbjct: 90 HPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSA-----PPASSSAPPATP-------- 136
Query: 1083 NPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQ 1142
P S G +P V PP PP S + G P+ P P
Sbjct: 137 -PTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG 195
Query: 1143 PVPALAPGP 1151
P P PGP
Sbjct: 196 PGPKQGPGP 204
Score = 38.1 bits (87), Expect = 0.10
Identities = 36/119 (30%), Positives = 42/119 (35%), Gaps = 20/119 (16%)
Query: 1902 QQCPGTPSSEMEQLDRPGLSQPGALGIANPLL--AVPAPSPEHSSPSVRLLPSAPQTLPD 1959
QQ P P + + G +G A P A PA P +P S P P
Sbjct: 97 QQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP----GSGPGPTPT 152
Query: 1960 GPLASPARVPMFPVPLPP------------GPLEPGPGCVTPGPALGFLEPSGPGLPPG 2006
P A + P P P PP GP P P PGP G + GPG P G
Sbjct: 153 PPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGP--PPPPAAVPGPGPGPKQGPGPGGPKG 209
Score = 37.7 bits (86), Expect = 0.13
Identities = 48/202 (23%), Positives = 60/202 (29%), Gaps = 40/202 (19%)
Query: 1908 PSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPAR 1967
P + Q P PG G P+ P + P + P P P P +
Sbjct: 36 PGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQ 95
Query: 1968 VPMFPVPLPPGPLEP----GPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSP 2023
P P P +P GPG P P +G P+ PP PP
Sbjct: 96 QQQ-PPPPPQDSSKPVVAQGPG---PAPGVGSAPPASSSAPPATPPTS----------GA 141
Query: 2024 DPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLS 2083
PG P P P+ T APP + PT PP +
Sbjct: 142 PPGSGPGPTPTP------------------PPAVTSAPPGAPPPTPPSSGVPTTPPQAGG 183
Query: 2084 PAPETKRPGQAAKKETKEPKKG 2105
P P P A PK+G
Sbjct: 184 PPP----PPAAVPGPGPGPKQG 201
Score = 37.0 bits (84), Expect = 0.23
Identities = 39/146 (26%), Positives = 52/146 (35%), Gaps = 19/146 (13%)
Query: 1027 PRQSGPGAP-NLDRFYQQVTKDAQGQPGLERAQQELVPP------QQQASPPQLPKAMFS 1079
P QSGP P +QQ + QP ++ PP QQQ PP +
Sbjct: 51 PGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPV 110
Query: 1080 ELSNPESLPAQGQAQNSAQS------PASLVLVDAGQQLPPRPPQSSSVSLVSS------ 1127
P P G A ++ S P S +G P PP + + + +
Sbjct: 111 VAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPP 170
Query: 1128 GSGQAAVPSEQPWPQPVPALAPGPPP 1153
SG P + P P PA PGP P
Sbjct: 171 SSGVPTTPPQAGGPPPPPAAVPGPGP 196
Score = 32.7 bits (73), Expect = 4.3
Identities = 37/138 (26%), Positives = 44/138 (31%), Gaps = 24/138 (17%)
Query: 1901 PQQCPGTPSSEMEQLDRP---GLSQPGALGIANPLLAVPAPSPEHSS--PSVRLLPSAPQ 1955
P Q P P +Q P S+P P V + P SS P+ AP
Sbjct: 84 PHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP 143
Query: 1956 TLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRH 2015
GP +P P P P P G T P G GP PP
Sbjct: 144 GSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAG-----GPPPPP---------- 188
Query: 2016 LLQEARSPDPGIVPQEAP 2033
A P PG P++ P
Sbjct: 189 ----AAVPGPGPGPKQGP 202
Score = 32.3 bits (72), Expect = 5.6
Identities = 38/151 (25%), Positives = 46/151 (30%), Gaps = 21/151 (13%)
Query: 1088 PAQGQAQNSAQSPASLVLVDAGQQ--LPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVP 1145
P G N + P +G + +PP PP P QP P P P
Sbjct: 34 PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQP 93
Query: 1146 --ALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYD 1203
P PPPQ D+ +P + P PG S S P P
Sbjct: 94 HQQQQPPPPPQ------------DSSKPVVAQGPGPAPGVGSA--PPASSSAPPATPPTS 139
Query: 1204 GAASAYAQNYRYPEPERPSSRASHSSERPPP 1234
GA P P P + S PPP
Sbjct: 140 GAPPGSGPG---PTPTPPPAVTSAPPGAPPP 167
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 62.0 bits (149), Expect = 7e-09
Identities = 199/931 (21%), Positives = 309/931 (33%), Gaps = 132/931 (14%)
Query: 196 VTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGV---------PCATS 246
++PA+S S PGLQ G+ Q P+ H +P P + V P +T
Sbjct: 2203 LSPASSTS---PGLQ--GESTAFQ--THPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 2255
Query: 247 VPHFPTPS----------ILHQGPGHEQHSPLVA---------PPAALPSDGRDEVSHLQ 287
HFP S I H P +P A + S G E++ L
Sbjct: 2256 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 2315
Query: 288 SGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEH-----RPAS--ALVNPLAR- 339
+ S+ +TF +PR SP + GV E +P S + V+P +
Sbjct: 2316 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 2375
Query: 340 --GDSPENRTHHPLGAGAGSGCA-PLEADSGASGALAMFFQGGETENEENLSSEKAGLSG 396
G S E+ T + G+ P + G F L +E + SG
Sbjct: 2376 TPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG 2435
Query: 397 QADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQY 456
+ + + PG PA T G P+ D+ + ST P +SGS
Sbjct: 2436 LTE--ESTAFPG---SPASTQTGL----------PATLTTADLGEE--STTFPSSSGSTG 2478
Query: 457 ENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTG--APDATLH 514
+ + V S P L PSS G P++ +T +PDATL
Sbjct: 2479 TTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 2538
Query: 515 TVHPDSVS-SSYSSRSH---GRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQI--DS 568
S S SS SH G +A P + + + GS + S
Sbjct: 2539 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRH-STTSHSSPGSTDTTLLPAS 2597
Query: 569 SPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADR 628
+ G + E+T S + GS +P Q S P +H + P
Sbjct: 2598 TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTT-LFPDSTTS 2656
Query: 629 ANVVGEVRETCVRQKQCRPAAALPDA---SPGNLEQ-------PPDNMETLCAPQVCPLP 678
+ +V T V P L A SPG + P T P P
Sbjct: 2657 SGIV--EASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAP 2714
Query: 679 LNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESP----ATTLWAQSELPDF 734
+ +T H P G+ P T +PA + + SP T A S
Sbjct: 2715 VEEST-TYHRSP--GSTP-TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 2770
Query: 735 GGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQS--RNPSSAAPVQSRGGIGASENLE 792
G + + + + P EA + S R+P++ S +G E
Sbjct: 2771 GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGE--- 2827
Query: 793 NPPKMGEEEALQSQASSGYASL---LSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSL 849
E +SQ S ++++ ++ P S ++ V + P + P + + S+
Sbjct: 2828 ------ESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSV 2881
Query: 850 SNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVA-----Q 904
R A G + E+T+ G P S+ L + A
Sbjct: 2882 RGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEES 2941
Query: 905 SNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPA---GS 961
+ FP SG++ + + + P L P S + + LPG +P+ S
Sbjct: 2942 TTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTET----TTLPGSPTTPSLSEKS 2997
Query: 962 TSVVLVPPA-HGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQ 1020
T+ P + TL P ++ S + T + S+ + S + S SQ
Sbjct: 2998 TTFYTSPRSPDATLSPATTTSSGVSEESST------SHSQPGSTHTTAFPDSTTTSGLSQ 3051
Query: 1021 QSVASHPRQS------GPGAPNLDRFYQQVT 1045
+ ASH Q PG+ QQ T
Sbjct: 3052 EPTASHSSQGSTEATLSPGSTTASSLGQQST 3082
Score = 58.5 bits (140), Expect = 7e-08
Identities = 197/926 (21%), Positives = 298/926 (32%), Gaps = 129/926 (13%)
Query: 196 VTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGV---------PCATS 246
++PA+S S PGLQ G+ Q P+ H +P P + V P +T
Sbjct: 1120 LSPASSTS---PGLQ--GESTAFQ--THPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 1172
Query: 247 VPHFPTPS----------ILHQGPGHEQHSPLVA---------PPAALPSDGRDEVSHLQ 287
HFP S I H P +P A + S G E++ L
Sbjct: 1173 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 1232
Query: 288 SGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNE-----HRPAS--ALVNPLAR- 339
+ S+ +TF +PR SP + GV E +P S + V+P +
Sbjct: 1233 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 1292
Query: 340 --GDSPENRTHHPLGAGAGSGCA-PLEADSGASGALAMFFQGGETENEENLSSEKAGLSG 396
G S E+ T + G+ P + G F L +E + SG
Sbjct: 1293 TPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSG 1352
Query: 397 QADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQY 456
++ + PG PA T G P+ D+ + ST P +SGS
Sbjct: 1353 LT--EESTAFPG---SPASTQTGL----------PATLTTADLGEE--STTFPSSSGSTG 1395
Query: 457 ENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTG--APDATLH 514
+ + V S P L PSS G P++ +T +PDATL
Sbjct: 1396 TKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 1455
Query: 515 TVHPDSVS-SSYSSRSH---GRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSP 570
S S SS SH G +A P + + QE P S + SP
Sbjct: 1456 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQE---PTTSHSSQGSTEATLSP 1512
Query: 571 VGGETDETTVSQNYRGSVSQP-STPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRA 629
G T +++ Q S P T + P + + P S + +
Sbjct: 1513 --GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPAS 1570
Query: 630 NVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETL-CAPQVCP---LPLNSTT-- 683
+ ++E + ++ + PG P + T P P +STT
Sbjct: 1571 STSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLG 1630
Query: 684 -----EAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNV 738
VH P A L A T P+ S TT LP
Sbjct: 1631 RSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETT-----ALPGSTTTA 1685
Query: 739 LLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMG 798
L+ + Y + + P SG + +S + S + P
Sbjct: 1686 GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ 1745
Query: 799 EEEALQSQASSGYASLLSSPPTESLQNP--PVLIAQPDHSYNLAQPINFSVS-----LSN 851
E A S S +L T S P + P + P N + S +
Sbjct: 1746 ESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTP 1805
Query: 852 SHEKNQSWREAL--------VGDRPAVSSWALGGDS--GENTSLSGIPTSSVLSLSLPSS 901
H S L G+ SW D+ T+ S S S PSS
Sbjct: 1806 VHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSS 1865
Query: 902 VAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFA-NSPAG 960
++F S +S + + V S PV P + +G A +S G
Sbjct: 1866 TPTTHF---SASSTTLGRSEESTTVH--SSPVATATTPSPARSTTSGLVEESTAYHSSPG 1920
Query: 961 STSVVLVPPAHGTLVPDGNKANHSSHQEDTY--GALDFTLSRTLENPVNVYN-------- 1010
ST + P + ++ + +SH T+ + T S +E P + ++
Sbjct: 1921 STQTMHFP--ESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATT 1978
Query: 1011 ---PSHSDSLASQQSVASHPRQSGPG 1033
S + S S++S ASH Q G
Sbjct: 1979 HFPDSSTTSGRSEESTASHSSQDATG 2004
Score = 56.6 bits (135), Expect = 3e-07
Identities = 220/1195 (18%), Positives = 358/1195 (29%), Gaps = 171/1195 (14%)
Query: 4 PPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQ 63
P + +G P + S+P R ++ TT P P T +
Sbjct: 1388 PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET---TTLPGSPTTPSLSEKSTTFY 1444
Query: 64 STPLGSSSKSSPPVL--QGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHA 121
++P + SP G + + H HT A S + P T +
Sbjct: 1445 TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQG 1504
Query: 122 SPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPG 181
S L+P + + + + SS + +T I E S H
Sbjct: 1505 ST-EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTH------- 1556
Query: 182 LDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGG--PQPSGQHRSPCPEGPVPS 239
S +TPA+S S Q P P P G +P
Sbjct: 1557 -----SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYH 1611
Query: 240 GVPCATSVPHFPTPSI----------LHQGPG---------HEQHSPLVAPPAALP-SDG 279
P +T HF S +H PG S LV P P S G
Sbjct: 1612 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG 1671
Query: 280 RDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNE-----HRPASALV 334
E + L + A S+ +TF +PR + SP + GV E RP S
Sbjct: 1672 STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 1731
Query: 335 -----NPLARGDSPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSS 389
+ G S E+ H + +P + + G + F E L
Sbjct: 1732 TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLP 1791
Query: 390 EKAGLSG----QADFDDFCSSPGLGRPPA--PTHVGAGSLCQA------LLPGPSNEAAG 437
+ SG SP PA T G + Q+ +P P +
Sbjct: 1792 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSA 1851
Query: 438 DVWGDTASTGVPDASGSQYENVENLEFVQNQE------------VLPSEPLNLDPSSPSD 485
V T S G P ++ + + + + +++E PS + +
Sbjct: 1852 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 1911
Query: 486 QFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGT 545
Y PG H P+++ + + +S+SS +H S P
Sbjct: 1912 STAYHSSPGSTQTMH-------FPESSTASGRSEESRTSHSSTTHTISS----PPSTTSA 1960
Query: 546 FIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQT 605
+++ S + DSS G ++E+T S + + + P+ + +
Sbjct: 1961 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGE 2020
Query: 606 SANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDA---SPGNLEQP 662
S S P+ S + + T PA L A S G E+
Sbjct: 2021 STTS---PISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEES 2077
Query: 663 PDNMETLCAPQVCPLPLNSTTEAV---HMLPHAGAPPLD-TVYPAPEKRPSARTQGPVKC 718
+ + P ++TT + H+ D T+ PA +
Sbjct: 2078 TTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 2137
Query: 719 ESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAP 778
SP +T A S P + + + + P SG + +
Sbjct: 2138 SSPGSTDTALS--PGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSS 2195
Query: 779 VQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYN 838
S + + +P GE A Q+ +S T + +PP P
Sbjct: 2196 TGSPRTTLSPASSTSPGLQGESTAFQTHPAS----------THTTPSPPSTATAP----- 2240
Query: 839 LAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSL 898
V S ++ ++ G P A SG + + +S S +
Sbjct: 2241 --------VEESTTYHRSP-------GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 2285
Query: 899 PSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSP 958
PSS + +G + +S + P S P A F +SP
Sbjct: 2286 PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP-----------GLSEASTTFYSSP 2334
Query: 959 AGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLA 1018
T+ + PA T + G ++ S Q G+ T+S P + P S+
Sbjct: 2335 RSPTTT--LSPASMTSLGVGEESTTSRSQP---GSTHSTVS-----PASTTTPGLSEEST 2384
Query: 1019 SQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMF 1078
+ S S PG+ F + T +G+ P + P +F
Sbjct: 2385 TVYS-------SSPGSTETTVFPRTPTTSVRGEE----------PTTFHSRPASTHTTLF 2427
Query: 1079 SELSNPESLPAQ------GQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSS 1127
+E S L + A PA+L D G++ P S S S
Sbjct: 2428 TEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLS 2482
Score = 56.6 bits (135), Expect = 3e-07
Identities = 265/1312 (20%), Positives = 428/1312 (32%), Gaps = 241/1312 (18%)
Query: 69 SSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRA-HASPFSGA 127
S + S+ P LQG + A F HP TH S P P+ + H SP S
Sbjct: 3761 SPASSTSPGLQGESTA-FQTHPA----STHTTPS---PPSTATAPVEESTTYHRSPGSTP 3812
Query: 128 LT--PSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRP 185
T P++ + + + SS T P H E++ G+ P
Sbjct: 3813 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 3872
Query: 186 LSRQNP--HDGVVTPAASPSLPQPGLQMPGQWGPVQGGP-------QPSGQHRSPCPEGP 236
S P + T +SP P L P + G QP H + P
Sbjct: 3873 GSTTTPGLSEASTTFYSSPRSPTTTLS-PASMTSLGVGEESTTSRSQPGSTHSTVSPAST 3931
Query: 237 VPSGV-----------PCATSVPHFPT----------PSILHQGPGHEQH---------S 266
G+ P +T FP P+ H P S
Sbjct: 3932 TTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTS 3991
Query: 267 PLVAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNE 326
L A P + L + A+ + +TF + SP G+ E
Sbjct: 3992 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGE 4051
Query: 327 HRPASALVNPLARGDSPENRTHHPLGAGAGSG-CAPLEADSGASGALAMFFQGGETENEE 385
P+ + P + T L + + +P D+ S A G +E E
Sbjct: 4052 STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTT--SSGVSE-ES 4108
Query: 386 NLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPS------------N 433
+ S + G + F D ++ GL + P +H GS L PG + +
Sbjct: 4109 STSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH 4168
Query: 434 EAAGD-----VWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFR 488
+ GD + DT ++G+ +AS + + +L + + P+ + S F+
Sbjct: 4169 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL----HTTLTPASSTSTGLQEESTTFQ 4224
Query: 489 YGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSR------SHGRLSGSARPQEL 542
P P +P +T T P VS++Y SR +H S + +
Sbjct: 4225 SWPSSSDTTP---------SPPST--TAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE 4273
Query: 543 VGTFIQQEVGK------PEDEASGSFFKQIDSSPVGGETDETTV-------------SQN 583
T + G P A+ + +SP+ + ETT S
Sbjct: 4274 ESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 4333
Query: 584 YRGSVSQPSTPSPPKPT---GIFQTSANSSFEPVKSH---------LVGVKPFEADRANV 631
+ S P T P T G+ + S S P H + GV +
Sbjct: 4334 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSS 4393
Query: 632 VGEVRET----CVRQKQCRPAAALPDASPGNLEQP--PDNMETLCAPQVCPLPLNSTTEA 685
G T P + +SPG+ E PDN T P++S+T +
Sbjct: 4394 PGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDN-TTASGLLEASTPVHSSTGS 4452
Query: 686 VH-MLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSEL-------PDFGGN 737
H L AG+ + P+++ P +P TT A EL P
Sbjct: 4453 PHTTLSPAGSTTRQGESTTFQSWPNSKDTTP----APPTTTSAFVELSTTSHGSPSSTPT 4508
Query: 738 VLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQS---RGGIGASENLENP 794
+ ++ L + P A + +R+ +S +S G+++ + P
Sbjct: 4509 THFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFP 4568
Query: 795 PK---MGEEEALQSQASSGYASLLSSPPTES--LQNPPVLIAQPDHSYNLAQPINFSVS- 848
G E + SS ++ S+P T S ++ P + P + P + + S
Sbjct: 4569 ESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSG 4628
Query: 849 ---LSNSHEKNQSWREALVGDRPAVSSWALG--------GDSGENTSLSGIPTSSVLS-- 895
S + +Q +V + +S LG S E T+L G T+ LS
Sbjct: 4629 RSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEK 4688
Query: 896 ----LSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSAL 951
S PSS ++F S +S + + V S PV P + +G
Sbjct: 4689 STTFHSSPSSTPTTHF---SASSTTLGRSEESTTVH--SSPVATATTPSPARSTTSGLVE 4743
Query: 952 PGFA-NSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTY--GALDFTLSRTLENPVNV 1008
A +S GST + P + ++ + +SH T+ + T S +E P +
Sbjct: 4744 ESTAYHSSPGSTQTMHFP--ESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSY 4801
Query: 1009 YN-----------PSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQG------- 1050
++ S + S S++S ASH G L + + A+
Sbjct: 4802 HSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISP 4861
Query: 1051 ------------QPGLERAQQELV----PPQQQASPPQLPKAMFSELSNPESLPAQGQAQ 1094
PGL L P Q SP + + S P SL +Q ++
Sbjct: 4862 GSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSIS--GEPTSLYSQAEST 4919
Query: 1095 NSAQSPASLVLVDAGQQLPP--RPPQSSSVSL------VSSGSGQAAVPSEQPWP----- 1141
++ PAS Q+ P S+ +L SS + + P QP
Sbjct: 4920 HTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTV 4979
Query: 1142 QPVPALAPG-----------PPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPG 1182
P PG P + A+ + + + Q S P+P PG
Sbjct: 4980 SPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTM--SIHSQQSTPFPDSPG 5029
Score = 53.5 bits (127), Expect = 2e-06
Identities = 208/1075 (19%), Positives = 355/1075 (33%), Gaps = 192/1075 (17%)
Query: 244 ATSVPHFPTPSILHQGPG---------HEQHSPLVAPPAALP-SDGRDEVSHLQSGSHLA 293
+T+ H ++ H GPG H S V P P + E + L + A
Sbjct: 215 STNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTA 274
Query: 294 NNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNP----------LARGDSP 343
S+ +TF +PR + SP + GV + + + P G S
Sbjct: 275 GLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQ 334
Query: 344 ENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFD-D 402
E+ H + + +P + G + F + + SG +
Sbjct: 335 ESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTP 394
Query: 403 FCSSPG-----LGRPPAPTHVGAGSLCQA------LLPGPSNEAAGDVWGDTASTGVPDA 451
SS G L + TH G + Q+ P PS + V T P +
Sbjct: 395 VHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSS 454
Query: 452 SGSQYENVENLEFVQNQEVLP--SEPLNLDPSSP----------SDQFRYGPLPGPAVPR 499
+ + + + + ++E P S P+ + P + Y PG
Sbjct: 455 TPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTM 514
Query: 500 HGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEAS 559
H P+++ + H + ++ + S +H + S + L T +G E
Sbjct: 515 H-------FPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTET--- 564
Query: 560 GSFFKQIDSSPVGGETDETTVSQNYRGSVSQP-----STPS--------PPKPTGIFQTS 606
+ F+ DSS + G ++E+ S + +++ STPS P +G +T+
Sbjct: 565 -THFR--DSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETT 621
Query: 607 A--NSSFEP---VKSHLVGVKPFEADRANVVGEVRETCVRQK----QCRPAAALPDASPG 657
A S+ +P KS P D ++ + + V ++ RP + A PG
Sbjct: 622 ALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG 681
Query: 658 NLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPS-------- 709
+ P + E+ A P P ++T + P T + P +
Sbjct: 682 STTMPGLSQES-TASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTT 740
Query: 710 ------------ARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPV 757
+ T+ P SPA + Q E F P++ +P PP
Sbjct: 741 ASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHS----WPSSKD----TRPAPPT 792
Query: 758 VQ----PPEEAMSGQQSRNPSSAAPVQS------------RGGIGASENL---ENPPKMG 798
P G S P++ +S G+++ + E+ G
Sbjct: 793 TTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG 852
Query: 799 EEEALQSQASSGYASLLSSPPTES--LQNPPVLIAQPDHSYNLAQPINFSVS----LSNS 852
E + SS ++ S+P T S ++ P + P + P + + S S +
Sbjct: 853 RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 912
Query: 853 HEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSG 912
+Q +V + +S LG ++ S I + S+ + +LP S + S
Sbjct: 913 SHSSQDATGTIVLPARSTTSVLLG-----ESTTSPISSGSMETTALPGSTTTPGLSERST 967
Query: 913 ASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKA-----------GSALPGF------A 955
PA L P+ + ES R + PG +
Sbjct: 968 TFHSSPRSPATTL--SPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTS 1025
Query: 956 NSPAGSTSVVLVPPAHGTLVP--DGNKANHSSHQEDT------YGALDFTLSRTL--ENP 1005
+S GST L+P + T P + ++ SS DT AL F T NP
Sbjct: 1026 HSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNP 1085
Query: 1006 VNVYNPSHSDSLASQQSVASHPR-QSGPGAPNLDRFYQQVTKDAQGQPGLE----RAQQE 1060
+ + DS S V + R S G+P ++ + PGL+ Q
Sbjct: 1086 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPR-----TTLSPASSTSPGLQGESTAFQTH 1140
Query: 1061 LVPPQQQASPPQLPKAMFSELS----NPESLPA---QGQAQNSAQSPASLVLVDAGQQLP 1113
SPP A E + +P S P + S S S + +
Sbjct: 1141 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG 1200
Query: 1114 PRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPG----PPPQDLAAYYYYRP 1164
P SS +SG G++ P + L PG P + + +Y P
Sbjct: 1201 TTP---SSAHSTTSGRGESTTSRISPGSTEITTL-PGSTTTPGLSEASTTFYSSP 1251
Score = 47.4 bits (111), Expect = 2e-04
Identities = 250/1236 (20%), Positives = 393/1236 (31%), Gaps = 221/1236 (17%)
Query: 69 SSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRA-HASPFSGA 127
S + S+ P LQG + F HP TH S P P+ + H SP S
Sbjct: 2678 SPASSTSPGLQGESTT-FQTHPA----STHTTPS---PPSTATAPVEESTTYHRSPGSTP 2729
Query: 128 LT--PSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRP 185
T P++ + + + SS T P H E++ G+ P
Sbjct: 2730 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 2789
Query: 186 LSRQNP--HDGVVTPAASPSLPQPGLQMPGQWGPVQGGP-------QPSGQHRSPCPEGP 236
S P + T +SP P L P + G QP H + P
Sbjct: 2790 GSTTTPGLSEASTTFYSSPRSPTTTLS-PASMTSLGVGEESTTSRSQPGSTHSTVSPAST 2848
Query: 237 VPSGV-----------PCATSVPHFPT----------PSILHQGPGHEQH---------S 266
G+ P +T FP P+ H P S
Sbjct: 2849 TTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTS 2908
Query: 267 PLVAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNE 326
L A P + L + A+ + +TF + SP G+ E
Sbjct: 2909 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGE 2968
Query: 327 HRPASALVNPLARGDSPENRTHHPLGAGAGSG-CAPLEADSGASGALAMFFQGGETENEE 385
P+ + P + T L + + +P D+ S A G +E E
Sbjct: 2969 STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTT--SSGVSE-ES 3025
Query: 386 NLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPS------------N 433
+ S + G + F D ++ GL + P +H GS L PG + +
Sbjct: 3026 STSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFH 3085
Query: 434 EAAGD-----VWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFR 488
+ GD + DT ++G+ +AS + + +L + + P+ + S F+
Sbjct: 3086 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL----HTTLTPASSTSAGLQEESTTFQ 3141
Query: 489 YGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSR------SHGRLSGSARPQEL 542
P P +P T T P VS++Y SR +H S + +
Sbjct: 3142 SWPSSSDTTP---------SPPGT--TAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE 3190
Query: 543 VGTFIQQEVGK------PEDEASGSFFKQIDSSPVGGETDETTV-------------SQN 583
T + G P A+ + +SP+ + ETT S
Sbjct: 3191 ESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 3250
Query: 584 YRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQK 643
+ S P T P T TS+ S E SH +P G V Q+
Sbjct: 3251 FYSSPRSPDTTLSPAST----TSSGVSEESTTSH---SRPGSTHTTAFPGSTTMPGVSQE 3303
Query: 644 QCRPAAALPDASPGNLE---QPPDNMETLCAPQVCPLPLNSTTEAVHMLPH--AGAPPLD 698
+ +SPG+ + P + P+ + +LP + L+
Sbjct: 3304 -----STASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLE 3358
Query: 699 TVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVV 758
P + T P SPA + Q E F PA PP
Sbjct: 3359 ASTPV-----HSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPA--------PPTT 3405
Query: 759 QPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSP 818
+S +PSS AS +G E + SS A+ +
Sbjct: 3406 TSAFVELSTTSHGSPSSTPTTH----FSASST-----TLGRSEESTTVHSSPVATATTPS 3456
Query: 819 PTESLQNPPVLIAQPDHSY-NLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGG 877
P S + V + HS Q ++F S + S +S + ++ +
Sbjct: 3457 PARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTS------HSSTTHTISS 3510
Query: 878 DSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQG---SGASE----MVSNQPANLLVQPPS 930
++L PTS S P S A ++FP SG SE S+Q A + P+
Sbjct: 3511 APSTTSALVEEPTS---YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 3567
Query: 931 QPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDT 990
+ L+ ES SP S S+ T P ++ + + H
Sbjct: 3568 RSTTSVLLGES-------------TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSP- 3613
Query: 991 YGALDFTLSRTLENPVNVYNP-SHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQ 1049
+P +P S + S S++S SH R PG+ + F D+
Sbjct: 3614 ------------RSPATTLSPASTTSSGVSEESTTSHSR---PGSTHTTAF-----PDST 3653
Query: 1050 GQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQ--AQNSAQSPASLVLVD 1107
PGL R LP + + S+ ES + + ++A SP S +
Sbjct: 3654 TTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALS 3713
Query: 1108 AGQQLPP--RPPQSSSVSL-----VSSGSGQAAVPSEQPWPQPVPALAP----GPPPQDL 1156
GQ+ P S+ +L SSG +A+ P L+P P Q
Sbjct: 3714 FGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGE 3773
Query: 1157 AAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVY 1192
+ + P ++ P PP A + Y
Sbjct: 3774 STAFQTHP-----ASTHTTPSPPSTATAPVEESTTY 3804
Score = 37.7 bits (86), Expect = 0.13
Identities = 206/1035 (19%), Positives = 333/1035 (32%), Gaps = 154/1035 (14%)
Query: 69 SSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRA-HASPFSGA 127
S + S+ P LQG + A F HP TH S P P+ + H SP S
Sbjct: 2204 SPASSTSPGLQGESTA-FQTHPA----STHTTPS---PPSTATAPVEESTTYHRSPGSTP 2255
Query: 128 LT--PSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRP 185
T P++ + + + SS T P H E++ G+ P
Sbjct: 2256 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 2315
Query: 186 LSRQNP--HDGVVTPAASPSLPQPGLQMPGQWGPVQGGP-------QPSGQHRSPCPEGP 236
S P + T +SP P L P + G QP H + P
Sbjct: 2316 GSTTTPGLSEASTTFYSSPRSPTTTLS-PASMTSLGVGEESTTSRSQPGSTHSTVSPAST 2374
Query: 237 VPSGV-----------PCATSVPHFPT----------PSILHQGPGHEQH---------S 266
G+ P +T FP P+ H P S
Sbjct: 2375 TTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTS 2434
Query: 267 PLVAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNE 326
L A P + L + A+ + +TF + SP G+ E
Sbjct: 2435 GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGE 2494
Query: 327 HRPASALVNPLARGDSPENRTHHPLGAGAGSG-CAPLEADSGASGALAMFFQGGETENEE 385
P+ + P + T L + + +P D+ S A G +E E
Sbjct: 2495 STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTT--SSGVSE-ES 2551
Query: 386 NLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTAS 445
+ S + G + F D ++PGL R +H GS LLP T +
Sbjct: 2552 STSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP-----------ASTTT 2600
Query: 446 TGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCH 505
+G S + + + P S G + + H
Sbjct: 2601 SGPSQESTTSHSS---------------------PGSTDTALSPGSTTALSFGQESTTFH 2639
Query: 506 TGAPDATLHTVHPDSVSSS----YSSRSHGRLSGSAR----PQELVGTFIQQEVGKPEDE 557
+ +P +T T+ PDS +SS S+R H +GS R P +Q E +
Sbjct: 2640 S-SPGSTHTTLFPDSTTSSGIVEASTRVHSS-TGSPRTTLSPASSTSPGLQGESTTFQTH 2697
Query: 558 ASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTG------IFQTSANSS- 610
+ + S +E+T GS P+ +G IF +S ++S
Sbjct: 2698 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG 2757
Query: 611 FEPVKSHLVGVKPFEADRANV-VGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETL 669
P +H E+ + + G T + P L +AS P TL
Sbjct: 2758 TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP--GLSEASTTFYSSPRSPTTTL 2815
Query: 670 CAPQVCPLPLNSTTEAVHMLP---HAGAPPLDTVYPA-PEKRPSARTQGPVKCESPATTL 725
+ L + + P H+ P T P E+ + + P E TT+
Sbjct: 2816 SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE---TTV 2872
Query: 726 WAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSS--AAPVQSRG 783
+ +S G P + E++ + + ++ +P ++
Sbjct: 2873 FPRSTTTSVRGE------EPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQT 2926
Query: 784 GIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDH---SYNLA 840
G+ A+ + +GEE +S + LS P S + V + P S
Sbjct: 2927 GLPATLTTAD---LGEESTTFPSSSGSTGTTLS--PARSTTSGLVGESTPSRLSPSSTET 2981
Query: 841 QPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPS 900
+ S + + EK+ ++ + P L S T+ SG+ S S S P
Sbjct: 2982 TTLPGSPTTPSLSEKSTTFYTS-----PRSPDATL---SPATTTSSGVSEESSTSHSQPG 3033
Query: 901 SVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAG 960
S + FP + S + A+ Q ++ L P S G F +SP G
Sbjct: 3034 STHTTAFPDSTTTSGLSQEPTASHSSQGSTE---ATLSPGSTTASSLGQQSTTFHSSP-G 3089
Query: 961 STSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYN--------PS 1012
T L+P T+ +A+ +H + G+L TL+ + PS
Sbjct: 3090 DTETTLLP--DDTITSGLVEASTPTH--SSTGSLHTTLTPASSTSAGLQEESTTFQSWPS 3145
Query: 1013 HSDSLASQQSVASHP 1027
SD+ S + P
Sbjct: 3146 SSDTTPSPPGTTAAP 3160
Score = 37.0 bits (84), Expect = 0.23
Identities = 118/598 (19%), Positives = 181/598 (30%), Gaps = 109/598 (18%)
Query: 27 ASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQSTPLGSSSKSSPPVLQGPAPAGF 86
+++ + R + + P + + V+ S + ST S S+ GP F
Sbjct: 3276 STTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTF 3335
Query: 87 SQHPG----LLVPHTHARDSSQGPCEPLPGPLTQPRAHASPFSGALTPSAPPG-----PE 137
PG L+P P+ P SP +G+ T P
Sbjct: 3336 HSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP-AGSTTRQGESTTFQSWPN 3394
Query: 138 MNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVT 197
+ P++ L H P P T H + L R H +
Sbjct: 3395 SKDTTPAPPTTTSAFVELSTTSHGSPSSTPTT----HFSASSTTLGRSEESTTVHS---S 3447
Query: 198 PAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSP-------CPEGPVPSGVPCATSVPHF 250
P A+ + P P G V+ + + H SP PE SG ++ H
Sbjct: 3448 PVATATTPSPARSTTS--GLVE---ESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS 3502
Query: 251 PTPSILHQGPGHEQHSPLVAPPAALPSD-GRDEVSHLQSGSHLANNSDPESTFRQNPRIV 309
T + P S LV P + S G +H S + S+ + +
Sbjct: 3503 STTHTISSAPSTT--SALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDAT 3560
Query: 310 NHWASP----------ELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGC 359
P E +P + + G S ++ T H +
Sbjct: 3561 GTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTL 3620
Query: 360 APLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAPTHVG 419
+P A + +SG E S + G + F D ++PGL R +H
Sbjct: 3621 SP--ASTTSSGV----------SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 3668
Query: 420 AGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLD 479
GS LLP + + ST +SGS + + P L
Sbjct: 3669 PGSTDTTLLPASTTTSG----SSQESTTSHSSSGS-----------TDTALSPGSTTALS 3713
Query: 480 PSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARP 539
S F +P +T T+ PDS +SS G + S R
Sbjct: 3714 FGQESTTFH------------------SSPGSTHTTLFPDSTTSS------GIVEASTR- 3748
Query: 540 QELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPP 597
+ G P S + SS G E+T Q + S +TPSPP
Sbjct: 3749 -------VHSSTGSPRTTLSPA------SSTSPGLQGESTAFQTHPASTH--TTPSPP 3791
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.0 bits (149), Expect = 7e-09
Identities = 102/402 (25%), Positives = 131/402 (32%), Gaps = 129/402 (32%)
Query: 1949 LLPSAPQTLPDGPLASPARVPMFPVPLP---PGPLEPGPGCV-TPGPALGFLEPSGPGLP 2004
LLP ++ P + P+ FPVP P GP EP + P P +G S P
Sbjct: 128 LLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPV 187
Query: 2005 PGVP-PLQERRH------LLQEARSPDPGIVPQEAP------VGNSLSELSEENFDGKFA 2051
P P P+Q H + R P PG P P +G S + F+
Sbjct: 188 PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFS 247
Query: 2052 NL-----TPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGE 2106
N TPSR + D PP P P RP + +E P
Sbjct: 248 NRPPLPPTPSRALDDKPPPP-----------------PPPVGNRP--SIHREAVPPP--- 285
Query: 2107 SWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQA 2166
P NK V + P +APPPPP
Sbjct: 286 -----------------PPQNNKPPV--------PSTPRPSASSQAPPPPP--------- 311
Query: 2167 APPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAP---ADFVAPLAPLPI 2223
PP+ PGPP P PS + E P + PLP
Sbjct: 312 -PPSRPGPPPLP--------------------PSSSGNDETPRLPQRNLSLSSSTPPLPS 350
Query: 2224 PSNLF-VPTPDAEEPQLP--DGTGREGPAAARGLANPEPAPEPKVLSSAASLPGS-ELPS 2279
P +P P +E P P D GR GP P P P + S++ +LP + +LPS
Sbjct: 351 PGRSGPLPPPPSERPPPPVRDPPGRSGPL-------PPPPPVSRNGSTSRALPATPQLPS 403
Query: 2280 SRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPP 2321
G + R L P D P+AG PP
Sbjct: 404 -----RSGVDSPRSGPRPPL-----------PPDRPSAGAPP 429
Score = 48.1 bits (113), Expect = 1e-04
Identities = 70/266 (26%), Positives = 87/266 (32%), Gaps = 55/266 (20%)
Query: 4 PPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQ 63
P Q+ P PP G PR P+ P P PF +R
Sbjct: 193 PIQSSPHNRGSPPVPGGPRQ-------------------PSPGPTPP---PFPGNR---- 226
Query: 64 STPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHASP 123
T LG S P L +P FS P L P T +R P P P +P H
Sbjct: 227 GTALGGGSIRQSP-LSSSSP--FSNRPPL--PPTPSRALDDKPPPPPPPVGNRPSIHRE- 280
Query: 124 FSGALTPSAPPGPEMNRSAEVGPSSEPEVQTL---PYLPHYIPGVD--PETSHGGHPHGN 178
+ PP P N V + P + P P PG P +S G
Sbjct: 281 -------AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPR 333
Query: 179 MPGLDRPLSRQNP------HDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPS-----GQ 227
+P + LS P G + P S P P PG+ GP+ P S +
Sbjct: 334 LPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSR 393
Query: 228 HRSPCPEGPVPSGVPCATSVPHFPTP 253
P+ P SGV S P P P
Sbjct: 394 ALPATPQLPSRSGVDSPRSGPRPPLP 419
Score = 44.3 bits (103), Expect = 0.001
Identities = 77/290 (26%), Positives = 97/290 (33%), Gaps = 38/290 (13%)
Query: 11 GMAGPPPAGNPRSVFWASSP-YRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQSTPLGS 69
G GPP G +F A P R AN + + PL P P G
Sbjct: 93 GGGGPPGLGG---LFQAGMPKLRSTANRDNDSGGSRPPLLP---------------PGGR 134
Query: 70 SSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHASPFSGALT 129
S+ + P P+G + P VP R GP EP + PR ++
Sbjct: 135 STSAKP----FSPPSGPGRFP---VPSPGHRS---GPPEPQRNRMPPPRPDVGSKPDSIP 184
Query: 130 PSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRPLSRQ 189
P P P +S+ S P V P P P P + G G PLS
Sbjct: 185 PPVPSTPRPIQSSPHNRGS-PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243
Query: 190 NPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPH 249
+P P P+ P L P G +PS HR P P + P VP
Sbjct: 244 SPFSN--RPPLPPT-PSRALDDKPPPPPPPVGNRPS-IHREAVPPPPPQNNKP---PVPS 296
Query: 250 FPTPSILHQGPGHEQHSPLVAPPAALP-SDGRDEVSHLQSGSHLANNSDP 298
P PS Q P PP P S G DE L + ++S P
Sbjct: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTP 346
Score = 43.1 bits (100), Expect = 0.003
Identities = 81/344 (23%), Positives = 110/344 (31%), Gaps = 86/344 (25%)
Query: 1936 PAPSPEHSS----PSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGP-------LEPGP 1984
P PSP H S P +P + P + P VP P P+ P + GP
Sbjct: 151 PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGP 210
Query: 1985 GCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEE 2044
+PGP PP P PG + +G S
Sbjct: 211 RQPSPGPT-----------PP-----------------PFPG--NRGTALGGGSIRQSPL 240
Query: 2045 NFDGKFANL-----TPSRTVPDSEAP--------PGWDRADSGPTQPPLSLSPAPETKRP 2091
+ F+N TPSR + D P P R P P + P P T RP
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
Query: 2092 GQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNE-----P 2146
+++ P P + LP + + + ++L+ P
Sbjct: 301 SASSQAPPPPP-----------PPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLP 349
Query: 2147 EEEKKAP-PPPPTSMPKTVQAAPPALPG--PPGAPVNMYSRRAAGTRARYVDVLNPSGTQ 2203
+ P PPPP+ P PP G PP PV SR + +RA PS +
Sbjct: 350 SPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV---SRNGSTSRALPATPQLPSRSG 406
Query: 2204 RSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREG 2247
P P PLP P P+ A P P + R G
Sbjct: 407 VDSPRSGPR------PPLP-PDR---PSAGAPPPPPPSTSIRNG 440
Score = 42.0 bits (97), Expect = 0.007
Identities = 83/377 (22%), Positives = 116/377 (30%), Gaps = 77/377 (20%)
Query: 1905 PGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSS--PSVRLLPSAPQTLPDGPL 1962
PG S+ + P S PG + +P P P+ + P + S P ++P
Sbjct: 131 PGGRSTSAKPFSPP--SGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVP 188
Query: 1963 ASPARVPMFP-----VPLPPGPLEPGPGCVTP------GPALGF-------LEPSGPGL- 2003
++P + P P+P GP +P PG P G ALG L S P
Sbjct: 189 STPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 2004 ----------------PPGVPPLQERRHLLQEARSPDP-------------------GIV 2028
PP PP+ R + +EA P P
Sbjct: 249 RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308
Query: 2029 PQEAPVGNSLSELSEENFDGKFANLTPSRTVP-DSEAPPGWDRADSGPTQPPLSLSPAPE 2087
P P L + P R + S PP SGP PP S P P
Sbjct: 309 PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368
Query: 2088 TKRP-GQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEP 2146
+ P G++ P R LP + + D +S + + P
Sbjct: 369 VRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS-----GPRPPLPPDRP 423
Query: 2147 EEEKKAPPPPPTSMPKTVQAAP------------PALPGPPGAPVNMYSRRAAGTRARYV 2194
PPPP TS+ Q +P P PP P ++ AR
Sbjct: 424 SAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNE 483
Query: 2195 DVLNPSGTQRSEPALAP 2211
+ +R P L P
Sbjct: 484 SRSGSNRRERGAPPLPP 500
Score = 39.3 bits (90), Expect = 0.046
Identities = 70/264 (26%), Positives = 89/264 (33%), Gaps = 63/264 (23%)
Query: 5 PQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQS 64
P ++P PP PR + SSP+ R + P P PF +R
Sbjct: 180 PDSIP-----PPVPSTPRPI--QSSPHNR-GSPPVPGGPRQPSPGPTPPPFPGNR----G 227
Query: 65 TPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHASPF 124
T LG S P L +P FS P L P T +R P P P +P H
Sbjct: 228 TALGGGSIRQSP-LSSSSP--FSNRPPL--PPTPSRALDDKPPPPPPPVGNRPSIHRE-- 280
Query: 125 SGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDR 184
+ PP P N V + P + P P S G P +P
Sbjct: 281 ------AVPPPPPQNNKPPVPSTPRPSASS------QAPPPPPPPSRPGPPP--LP---- 322
Query: 185 PLSRQNPHDGVVTPAASPSLPQ---------PGLQMPGQWGPVQGGPQPSGQHRSPCPEG 235
P S N +P LPQ P L PG+ GP+ P PS + P +
Sbjct: 323 PSSSGNDE--------TPRLPQRNLSLSSSTPPLPSPGRSGPLP--PPPSERPPPPVRDP 372
Query: 236 PVPSGVPCATSVPHFPTPSILHQG 259
P SG P P P + G
Sbjct: 373 PGRSG-------PLPPPPPVSRNG 389
Score = 37.0 bits (84), Expect = 0.23
Identities = 40/175 (22%), Positives = 62/175 (35%), Gaps = 18/175 (10%)
Query: 656 PGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPH-AGAPPLDTVYPAPEKRPSARTQG 714
P PP + P P P+ ST + PH G+PP+ P ++PS
Sbjct: 164 PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPV----PGGPRQPSPGPTP 219
Query: 715 PVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPS 774
P + T L GG++ +P + + +PP+ P A+ + P
Sbjct: 220 PPFPGNRGTALG--------GGSIRQSPLSSSSPF--SNRPPLPPTPSRAL---DDKPPP 266
Query: 775 SAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVL 829
PV +R I PP+ + + S + PP S PP L
Sbjct: 267 PPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPL 321
Score = 35.8 bits (81), Expect = 0.51
Identities = 74/350 (21%), Positives = 117/350 (33%), Gaps = 57/350 (16%)
Query: 917 VSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVP 976
V ++P ++ PS P P P + + +PG P+ + P GT +
Sbjct: 176 VGSKPDSIPPPVPSTPRPIQSSPHN----RGSPPVPGGPRQPSPGPTPPPFPGNRGTALG 231
Query: 977 DGNKANH---SSHQEDTYGALDFTLSRTLENPVNVYNP--SHSDSLASQQSVASHPRQSG 1031
G+ SS L T SR L++ P + S+ + P+ +
Sbjct: 232 GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK 291
Query: 1032 PGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASP-----PQLPKAMFSELSNPES 1086
P P+ R + +Q P + PP +S P+LP+ S S+
Sbjct: 292 PPVPSTPR----PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP 347
Query: 1087 LPAQGQA----QNSAQSPASLVLVDAGQQ--LPPRPPQSSSVSLVSSGSGQAAVPSEQPW 1140
LP+ G++ ++ P V G+ LPP PP S +GS A+P+
Sbjct: 348 LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVS------RNGSTSRALPATPQL 401
Query: 1141 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGA----------------A 1184
P +P P RP +P P PP P +
Sbjct: 402 PSRSGVDSPRSGP---------RPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWES 452
Query: 1185 SLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPP 1234
Y+ + L P PY +Y E S+R + PP
Sbjct: 453 RFYFHPISDLPPP--EPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPP 500
Score = 31.6 bits (70), Expect = 9.6
Identities = 55/246 (22%), Positives = 78/246 (31%), Gaps = 50/246 (20%)
Query: 1023 VASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELS 1082
V S +SGP P +R +P + + PP P P+ + S
Sbjct: 152 VPSPGHRSGPPEPQRNRM-------PPPRPDVGSKPDSIPPPV-----PSTPRPIQSSPH 199
Query: 1083 NPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQ 1142
N S P G + + P PP P + +L Q+ + S P+
Sbjct: 200 NRGSPPVPGGPRQPSPGPT-----------PPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 1143 -----PVPALA-----PGPPPQDLAAYYYYRPLYDAYQPQYS---LPYPPEPGAASLYYQ 1189
P P+ A P PPP +R PQ + +P P P A+S
Sbjct: 249 RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308
Query: 1190 DVYSLYEPRYRPYDGAASAYAQNYRYPE--------------PERPSSRASHSSERPPPR 1235
P P ++S + R P+ P R SERPPP
Sbjct: 309 PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368
Query: 1236 QGYPEG 1241
P G
Sbjct: 369 VRDPPG 374
Score = 31.6 bits (70), Expect = 9.6
Identities = 54/243 (22%), Positives = 75/243 (30%), Gaps = 51/243 (20%)
Query: 591 PSTP-----------SPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVG--EVRE 637
PSTP SPP P G Q S + PF +R +G +R+
Sbjct: 188 PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPT----------PPPFPGNRGTALGGGSIRQ 237
Query: 638 TCVRQKQC---------RPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHM 688
+ + P+ AL D P P N ++ V P P + V
Sbjct: 238 SPLSSSSPFSNRPPLPPTPSRALDDKPPPP-PPPVGNRPSIHREAVPPPPPQNNKPPVPS 296
Query: 689 LPHAGA------PPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAP 742
P A PP P P P + + P L S P P
Sbjct: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP 356
Query: 743 AAPALYVCAKPQPPVVQPPEEA----------MSGQQSRNPSSAAPVQSRGGIGASENLE 792
P +P PPV PP + +G SR + + SR G+ + +
Sbjct: 357 LPPP--PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414
Query: 793 NPP 795
PP
Sbjct: 415 RPP 417
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.0 bits (149), Expect = 7e-09
Identities = 102/402 (25%), Positives = 131/402 (32%), Gaps = 129/402 (32%)
Query: 1949 LLPSAPQTLPDGPLASPARVPMFPVPLP---PGPLEPGPGCV-TPGPALGFLEPSGPGLP 2004
LLP ++ P + P+ FPVP P GP EP + P P +G S P
Sbjct: 128 LLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPV 187
Query: 2005 PGVP-PLQERRH------LLQEARSPDPGIVPQEAP------VGNSLSELSEENFDGKFA 2051
P P P+Q H + R P PG P P +G S + F+
Sbjct: 188 PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFS 247
Query: 2052 NL-----TPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGE 2106
N TPSR + D PP P P RP + +E P
Sbjct: 248 NRPPLPPTPSRALDDKPPPP-----------------PPPVGNRP--SIHREAVPPP--- 285
Query: 2107 SWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQA 2166
P NK V + P +APPPPP
Sbjct: 286 -----------------PPQNNKPPV--------PSTPRPSASSQAPPPPP--------- 311
Query: 2167 APPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAP---ADFVAPLAPLPI 2223
PP+ PGPP P PS + E P + PLP
Sbjct: 312 -PPSRPGPPPLP--------------------PSSSGNDETPRLPQRNLSLSSSTPPLPS 350
Query: 2224 PSNLF-VPTPDAEEPQLP--DGTGREGPAAARGLANPEPAPEPKVLSSAASLPGS-ELPS 2279
P +P P +E P P D GR GP P P P + S++ +LP + +LPS
Sbjct: 351 PGRSGPLPPPPSERPPPPVRDPPGRSGPL-------PPPPPVSRNGSTSRALPATPQLPS 403
Query: 2280 SRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPP 2321
G + R L P D P+AG PP
Sbjct: 404 -----RSGVDSPRSGPRPPL-----------PPDRPSAGAPP 429
Score = 48.1 bits (113), Expect = 1e-04
Identities = 70/266 (26%), Positives = 87/266 (32%), Gaps = 55/266 (20%)
Query: 4 PPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQ 63
P Q+ P PP G PR P+ P P PF +R
Sbjct: 193 PIQSSPHNRGSPPVPGGPRQ-------------------PSPGPTPP---PFPGNR---- 226
Query: 64 STPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHASP 123
T LG S P L +P FS P L P T +R P P P +P H
Sbjct: 227 GTALGGGSIRQSP-LSSSSP--FSNRPPL--PPTPSRALDDKPPPPPPPVGNRPSIHRE- 280
Query: 124 FSGALTPSAPPGPEMNRSAEVGPSSEPEVQTL---PYLPHYIPGVD--PETSHGGHPHGN 178
+ PP P N V + P + P P PG P +S G
Sbjct: 281 -------AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPR 333
Query: 179 MPGLDRPLSRQNP------HDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPS-----GQ 227
+P + LS P G + P S P P PG+ GP+ P S +
Sbjct: 334 LPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSR 393
Query: 228 HRSPCPEGPVPSGVPCATSVPHFPTP 253
P+ P SGV S P P P
Sbjct: 394 ALPATPQLPSRSGVDSPRSGPRPPLP 419
Score = 44.3 bits (103), Expect = 0.001
Identities = 77/290 (26%), Positives = 97/290 (33%), Gaps = 38/290 (13%)
Query: 11 GMAGPPPAGNPRSVFWASSP-YRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQSTPLGS 69
G GPP G +F A P R AN + + PL P P G
Sbjct: 93 GGGGPPGLGG---LFQAGMPKLRSTANRDNDSGGSRPPLLP---------------PGGR 134
Query: 70 SSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHASPFSGALT 129
S+ + P P+G + P VP R GP EP + PR ++
Sbjct: 135 STSAKP----FSPPSGPGRFP---VPSPGHRS---GPPEPQRNRMPPPRPDVGSKPDSIP 184
Query: 130 PSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRPLSRQ 189
P P P +S+ S P V P P P P + G G PLS
Sbjct: 185 PPVPSTPRPIQSSPHNRGS-PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243
Query: 190 NPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPH 249
+P P P+ P L P G +PS HR P P + P VP
Sbjct: 244 SPFSN--RPPLPPT-PSRALDDKPPPPPPPVGNRPS-IHREAVPPPPPQNNKP---PVPS 296
Query: 250 FPTPSILHQGPGHEQHSPLVAPPAALP-SDGRDEVSHLQSGSHLANNSDP 298
P PS Q P PP P S G DE L + ++S P
Sbjct: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTP 346
Score = 43.1 bits (100), Expect = 0.003
Identities = 81/344 (23%), Positives = 110/344 (31%), Gaps = 86/344 (25%)
Query: 1936 PAPSPEHSS----PSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGP-------LEPGP 1984
P PSP H S P +P + P + P VP P P+ P + GP
Sbjct: 151 PVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGP 210
Query: 1985 GCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEE 2044
+PGP PP P PG + +G S
Sbjct: 211 RQPSPGPT-----------PP-----------------PFPG--NRGTALGGGSIRQSPL 240
Query: 2045 NFDGKFANL-----TPSRTVPDSEAP--------PGWDRADSGPTQPPLSLSPAPETKRP 2091
+ F+N TPSR + D P P R P P + P P T RP
Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300
Query: 2092 GQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNE-----P 2146
+++ P P + LP + + + ++L+ P
Sbjct: 301 SASSQAPPPPP-----------PPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLP 349
Query: 2147 EEEKKAP-PPPPTSMPKTVQAAPPALPG--PPGAPVNMYSRRAAGTRARYVDVLNPSGTQ 2203
+ P PPPP+ P PP G PP PV SR + +RA PS +
Sbjct: 350 SPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV---SRNGSTSRALPATPQLPSRSG 406
Query: 2204 RSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREG 2247
P P PLP P P+ A P P + R G
Sbjct: 407 VDSPRSGPR------PPLP-PDR---PSAGAPPPPPPSTSIRNG 440
Score = 42.0 bits (97), Expect = 0.007
Identities = 83/377 (22%), Positives = 116/377 (30%), Gaps = 77/377 (20%)
Query: 1905 PGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSS--PSVRLLPSAPQTLPDGPL 1962
PG S+ + P S PG + +P P P+ + P + S P ++P
Sbjct: 131 PGGRSTSAKPFSPP--SGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVP 188
Query: 1963 ASPARVPMFP-----VPLPPGPLEPGPGCVTP------GPALGF-------LEPSGPGL- 2003
++P + P P+P GP +P PG P G ALG L S P
Sbjct: 189 STPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 2004 ----------------PPGVPPLQERRHLLQEARSPDP-------------------GIV 2028
PP PP+ R + +EA P P
Sbjct: 249 RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308
Query: 2029 PQEAPVGNSLSELSEENFDGKFANLTPSRTVP-DSEAPPGWDRADSGPTQPPLSLSPAPE 2087
P P L + P R + S PP SGP PP S P P
Sbjct: 309 PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368
Query: 2088 TKRP-GQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEP 2146
+ P G++ P R LP + + D +S + + P
Sbjct: 369 VRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS-----GPRPPLPPDRP 423
Query: 2147 EEEKKAPPPPPTSMPKTVQAAP------------PALPGPPGAPVNMYSRRAAGTRARYV 2194
PPPP TS+ Q +P P PP P ++ AR
Sbjct: 424 SAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNE 483
Query: 2195 DVLNPSGTQRSEPALAP 2211
+ +R P L P
Sbjct: 484 SRSGSNRRERGAPPLPP 500
Score = 39.3 bits (90), Expect = 0.046
Identities = 70/264 (26%), Positives = 89/264 (33%), Gaps = 63/264 (23%)
Query: 5 PQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQS 64
P ++P PP PR + SSP+ R + P P PF +R
Sbjct: 180 PDSIP-----PPVPSTPRPI--QSSPHNR-GSPPVPGGPRQPSPGPTPPPFPGNR----G 227
Query: 65 TPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHASPF 124
T LG S P L +P FS P L P T +R P P P +P H
Sbjct: 228 TALGGGSIRQSP-LSSSSP--FSNRPPL--PPTPSRALDDKPPPPPPPVGNRPSIHRE-- 280
Query: 125 SGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDR 184
+ PP P N V + P + P P S G P +P
Sbjct: 281 ------AVPPPPPQNNKPPVPSTPRPSASS------QAPPPPPPPSRPGPPP--LP---- 322
Query: 185 PLSRQNPHDGVVTPAASPSLPQ---------PGLQMPGQWGPVQGGPQPSGQHRSPCPEG 235
P S N +P LPQ P L PG+ GP+ P PS + P +
Sbjct: 323 PSSSGNDE--------TPRLPQRNLSLSSSTPPLPSPGRSGPLP--PPPSERPPPPVRDP 372
Query: 236 PVPSGVPCATSVPHFPTPSILHQG 259
P SG P P P + G
Sbjct: 373 PGRSG-------PLPPPPPVSRNG 389
Score = 37.0 bits (84), Expect = 0.23
Identities = 40/175 (22%), Positives = 62/175 (35%), Gaps = 18/175 (10%)
Query: 656 PGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPH-AGAPPLDTVYPAPEKRPSARTQG 714
P PP + P P P+ ST + PH G+PP+ P ++PS
Sbjct: 164 PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPV----PGGPRQPSPGPTP 219
Query: 715 PVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPS 774
P + T L GG++ +P + + +PP+ P A+ + P
Sbjct: 220 PPFPGNRGTALG--------GGSIRQSPLSSSSPF--SNRPPLPPTPSRAL---DDKPPP 266
Query: 775 SAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVL 829
PV +R I PP+ + + S + PP S PP L
Sbjct: 267 PPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPL 321
Score = 35.8 bits (81), Expect = 0.51
Identities = 74/350 (21%), Positives = 117/350 (33%), Gaps = 57/350 (16%)
Query: 917 VSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVP 976
V ++P ++ PS P P P + + +PG P+ + P GT +
Sbjct: 176 VGSKPDSIPPPVPSTPRPIQSSPHN----RGSPPVPGGPRQPSPGPTPPPFPGNRGTALG 231
Query: 977 DGNKANH---SSHQEDTYGALDFTLSRTLENPVNVYNP--SHSDSLASQQSVASHPRQSG 1031
G+ SS L T SR L++ P + S+ + P+ +
Sbjct: 232 GGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK 291
Query: 1032 PGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASP-----PQLPKAMFSELSNPES 1086
P P+ R + +Q P + PP +S P+LP+ S S+
Sbjct: 292 PPVPSTPR----PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP 347
Query: 1087 LPAQGQA----QNSAQSPASLVLVDAGQQ--LPPRPPQSSSVSLVSSGSGQAAVPSEQPW 1140
LP+ G++ ++ P V G+ LPP PP S +GS A+P+
Sbjct: 348 LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVS------RNGSTSRALPATPQL 401
Query: 1141 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGA----------------A 1184
P +P P RP +P P PP P +
Sbjct: 402 PSRSGVDSPRSGP---------RPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWES 452
Query: 1185 SLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPP 1234
Y+ + L P PY +Y E S+R + PP
Sbjct: 453 RFYFHPISDLPPP--EPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPP 500
Score = 31.6 bits (70), Expect = 9.6
Identities = 55/246 (22%), Positives = 78/246 (31%), Gaps = 50/246 (20%)
Query: 1023 VASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELS 1082
V S +SGP P +R +P + + PP P P+ + S
Sbjct: 152 VPSPGHRSGPPEPQRNRM-------PPPRPDVGSKPDSIPPPV-----PSTPRPIQSSPH 199
Query: 1083 NPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQ 1142
N S P G + + P PP P + +L Q+ + S P+
Sbjct: 200 NRGSPPVPGGPRQPSPGPT-----------PPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248
Query: 1143 -----PVPALA-----PGPPPQDLAAYYYYRPLYDAYQPQYS---LPYPPEPGAASLYYQ 1189
P P+ A P PPP +R PQ + +P P P A+S
Sbjct: 249 RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308
Query: 1190 DVYSLYEPRYRPYDGAASAYAQNYRYPE--------------PERPSSRASHSSERPPPR 1235
P P ++S + R P+ P R SERPPP
Sbjct: 309 PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368
Query: 1236 QGYPEG 1241
P G
Sbjct: 369 VRDPPG 374
Score = 31.6 bits (70), Expect = 9.6
Identities = 54/243 (22%), Positives = 75/243 (30%), Gaps = 51/243 (20%)
Query: 591 PSTP-----------SPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVG--EVRE 637
PSTP SPP P G Q S + PF +R +G +R+
Sbjct: 188 PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPT----------PPPFPGNRGTALGGGSIRQ 237
Query: 638 TCVRQKQC---------RPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHM 688
+ + P+ AL D P P N ++ V P P + V
Sbjct: 238 SPLSSSSPFSNRPPLPPTPSRALDDKPPPP-PPPVGNRPSIHREAVPPPPPQNNKPPVPS 296
Query: 689 LPHAGA------PPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAP 742
P A PP P P P + + P L S P P
Sbjct: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP 356
Query: 743 AAPALYVCAKPQPPVVQPPEEA----------MSGQQSRNPSSAAPVQSRGGIGASENLE 792
P +P PPV PP + +G SR + + SR G+ + +
Sbjct: 357 LPPP--PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP 414
Query: 793 NPP 795
PP
Sbjct: 415 RPP 417
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 61.2 bits (147), Expect = 1e-08
Identities = 80/283 (28%), Positives = 97/283 (34%), Gaps = 47/283 (16%)
Query: 1 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 60
M+ PP PS AGPP P P R P + P P P
Sbjct: 214 MEKPPAP-PSLPAGPPGVKRPPPPLMNGLPPR-------PPLPESLPPPP---PGGLPLP 262
Query: 61 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAH 120
+ T S PP L PAP P + P + + G P PG
Sbjct: 263 PMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGV 322
Query: 121 ASPFSGALTPSA---PPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHG 177
P SG P+ PP P ++ A P P P + PGV P S G HP
Sbjct: 323 HPPTSGVHPPAPGVHPPAPGVHPPA---PGVHPPA---PGVHPPAPGVHPPPSAGVHPQA 376
Query: 178 NMPGLDRPLSRQNPHDGVVTPAASPSLPQ-PGLQMPGQWGPVQGGPQPSGQHRSPCPEGP 236
PG+ +P V P A PQ PG+ PQP G H S P
Sbjct: 377 --PGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVH-----------PQPPGVHPSAPGVHP 423
Query: 237 VPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDG 279
P GV + H PTP P++ PP LPS+G
Sbjct: 424 QPPGVHPSNPGVHPPTPM-----------PPMLRPP--LPSEG 453
Score = 39.7 bits (91), Expect = 0.035
Identities = 37/141 (26%), Positives = 47/141 (33%), Gaps = 22/141 (15%)
Query: 1900 LPQQCP-----GTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAP 1954
LP+ P G P M PG + P V P+P P+ + P AP
Sbjct: 247 LPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAP 306
Query: 1955 QTLPDGPLASPARVPMFPV-----PLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPP 2009
P P P + P P PG P PG P P + P PG+ P P
Sbjct: 307 GVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPG---VHPPAPGVHPPAPG 363
Query: 2010 LQERRHLLQEARSPDPGIVPQ 2030
+ P G+ PQ
Sbjct: 364 VHP---------PPSAGVHPQ 375
Score = 39.3 bits (90), Expect = 0.046
Identities = 56/202 (27%), Positives = 67/202 (33%), Gaps = 33/202 (16%)
Query: 156 PYLPHYIPGVD---PETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMP 212
P LP PGV P +G P +P P P G+ P P+ P P
Sbjct: 221 PSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPP----PPPGGLPLPPMPPTGPAPS---- 272
Query: 213 GQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPP 272
G GP Q P G H P SGV H P P + PG + V PP
Sbjct: 273 GPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPP 332
Query: 273 AALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASA 332
A G H P + P H +P + +P H P SA
Sbjct: 333 A--------------PGVH------PPAPGVHPPAPGVHPPAPGV--HPPAPGVHPPPSA 370
Query: 333 LVNPLARGDSPENRTHHPLGAG 354
V+P A G P HP G
Sbjct: 371 GVHPQAPGVHPAAPAVHPQAPG 392
Score = 38.5 bits (88), Expect = 0.079
Identities = 36/119 (30%), Positives = 45/119 (37%), Gaps = 12/119 (10%)
Query: 1923 PGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPL-PPGPLE 1981
P +L P + P P + P LP + P G L P P P P PPGP +
Sbjct: 220 PPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQ 279
Query: 1982 ---PGPGCVTPGPAL----GFLEPSGPGL---PPGV-PPLQERRHLLQEARSPDPGIVP 2029
P PG P P + + P PG+ PGV PP P PG+ P
Sbjct: 280 LPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHP 338
Score = 38.5 bits (88), Expect = 0.079
Identities = 43/173 (24%), Positives = 62/173 (35%), Gaps = 24/173 (13%)
Query: 1918 PGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPP 1977
PG+ P A G+ P V P+P P+ + P AP P P P + P P
Sbjct: 313 PGVHPP-APGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPP-SA 370
Query: 1978 GPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNS 2037
G PG PA + P PG+ P P + + PG+ PQ V S
Sbjct: 371 GVHPQAPGVHPAAPA---VHPQAPGVHPPAPGMHPQA----------PGVHPQPPGVHPS 417
Query: 2038 LSELSEE--NFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPET 2088
+ + + P +P PP P++ P ++ P P T
Sbjct: 418 APGVHPQPPGVHPSNPGVHPPTPMPPMLRPP-------LPSEGPGNIPPPPPT 463
Score = 36.6 bits (83), Expect = 0.30
Identities = 35/95 (36%), Positives = 40/95 (42%), Gaps = 29/95 (30%)
Query: 1951 PSAPQTLPDGP-----------LASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPS 1999
P AP +LP GP P R P+ P LPP P PG + P P G PS
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPL-PESLPPPP--PGGLPLPPMPPTG-PAPS 272
Query: 2000 GPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPV 2034
GP PP +PP P PG+ P APV
Sbjct: 273 GPPGPPQLPP-------------PAPGVHP-PAPV 293
Score = 35.0 bits (79), Expect = 0.87
Identities = 64/297 (21%), Positives = 99/297 (33%), Gaps = 72/297 (24%)
Query: 909 QGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFA-----NSPAGSTS 963
QG ++ + A + P+QP PE + E +K K G PG+ +S G S
Sbjct: 74 QGKKHQTNLARRAAKEAKEAPAQPAPEKVKVEVKKFVKIGR--PGYKVTKQRDSEMGQQS 131
Query: 964 VVL----------VPPAHG-------TLVPDGNKANHSSHQEDTYGALDFTL-SRTLENP 1005
++ + P H + P + + + Y + F + SR ++
Sbjct: 132 LLFQIDYPEIAEGIMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIAFKVPSREIDKA 191
Query: 1006 VNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQ 1065
+ +H + Q + H + P AP G PG++R PP
Sbjct: 192 EGKFW-THWNRETKQFFLQFHFKMEKPPAP---------PSLPAGPPGVKRPP----PPL 237
Query: 1066 QQASPPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLV 1125
PP+ P PESLP G LPP PP
Sbjct: 238 MNGLPPRPPL--------PESLPPPPPG---------------GLPLPPMPP-------- 266
Query: 1126 SSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPG 1182
+G + P P P P + P P A + P + P + +PP PG
Sbjct: 267 -TGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGV-HPPAPG 321
Score = 33.9 bits (76), Expect = 1.9
Identities = 42/168 (25%), Positives = 57/168 (33%), Gaps = 16/168 (9%)
Query: 2126 DKNKSIVWD----EKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNM 2181
DK + W E K ++ + E+ APP P P + PP + G P P
Sbjct: 189 DKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLP 248
Query: 2182 YSRRAAGTRARYVDVLNPSGTQRSEP-----ALAPADFVAPLAPL--PIPSNLFVPTPDA 2234
S + + P+G S P PA V P AP+ P S + P P
Sbjct: 249 ESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGV 308
Query: 2235 EEPQ---LPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPS 2279
P P G P + G+ P P P PG P+
Sbjct: 309 HPPAPGVHPPAPGVHPPTS--GVHPPAPGVHPPAPGVHPPAPGVHPPA 354
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 60.1 bits (144), Expect = 3e-08
Identities = 100/404 (24%), Positives = 146/404 (36%), Gaps = 64/404 (15%)
Query: 1883 VERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEH 1942
VE + E +GV + + ++ +S E + R S P + ++ ++P+P E
Sbjct: 700 VEDEEMEASGVSGNEEEMVEEAEALHASGNE-VPRGECSGPATVNNSSDTESIPSPHTEA 758
Query: 1943 SSPSVRLLPSAPQTL-PDGPLASPARVPMFPVPLP---PGPLEPGP-----GCVTPGPAL 1993
+ + + P P TL DGP P P P P P P EP P G TP PA
Sbjct: 759 AKDTGQNGPKPPATLGADGPPPGP------PTPPPEDIPAPTEPTPASEATGAPTPPPA- 811
Query: 1994 GFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANL 2053
P P PP V P +E+ +E + P + E + EL+ + GK
Sbjct: 812 ----PPSPSAPPPVVPKEEK----EEETAAAPPVEEGEEQKPPAAEELAVDT--GKAEEP 861
Query: 2054 TPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWL 2113
S ++E P + + A E G A K E KE G +
Sbjct: 862 VKSECTEEAEEGPAKGKD-----------AEAAEATAEG-ALKAEKKEGGSGRA------ 903
Query: 2114 PGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPG 2173
K + A D + + DE V+ E ++ + P P+ + T A P
Sbjct: 904 TTAKSSGAPQDSDSSATCSADE-----VDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQ 958
Query: 2174 PPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPD 2233
P + +RAA + P T+ EP A P P P P P D
Sbjct: 959 KP-LDLKQLKQRAA--------AIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESD 1009
Query: 2234 AEEPQLPDGTGR---EGPAAARGLANPEPAPEPKVLSSAASLPG 2274
A PQ P + R PA +P P + A LPG
Sbjct: 1010 A--PQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPG 1051
Score = 38.1 bits (87), Expect = 0.10
Identities = 137/569 (24%), Positives = 183/569 (32%), Gaps = 123/569 (21%)
Query: 5 PQTVPSGMAGPPPAGNPRS--VFWASSPYRRRANNNAAVAPTTCPLQPVTDPFA------ 56
P + PS + P P P S A +P + A ++A+ P P +DP
Sbjct: 1978 PASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPAS-ASDPHREKTQSK 2036
Query: 57 -FSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGL-----LVPHTHARDSS--QGPCE 108
FS Q L+ LG S P +G P P L L H D S +G
Sbjct: 2037 PFSIQELELRSLGYHGSSYSP--EGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELR 2094
Query: 109 PL-PGPLTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLP---------YL 158
P PGP+ L A P + E PSS P +QT P L
Sbjct: 2095 PKQPGPVK------------LGGEAAHLPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTL 2142
Query: 159 PHYIPGVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMP--GQWG 216
+I V + HP L PL G P P L +P
Sbjct: 2143 AQHISEVITQDYTRHHPQQLSAPLPAPLYS---FPGASCPVLDLRRPPSDLYLPPPDHGA 2199
Query: 217 PVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALP 276
P +G P G RSP P G P P + PGH + + V P L
Sbjct: 2200 PARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTE--PGHSRSA--VYP--LLY 2253
Query: 277 SDGRDEVSHLQSGSHLANNSDPESTFRQ----------------NPRIVNHWAS-PELR- 318
DG N S P + F + N ++ H + PE
Sbjct: 2254 RDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYNI 2313
Query: 319 QNPGVKNEHRPA------------------------SALVNPLARGDSPENRTHHPLGAG 354
PG + + PA A++ G + PL A
Sbjct: 2314 SQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGLEAIIRKALMGKYDQWEESPPLSAN 2373
Query: 355 AGSGCAPLEADSGASGALAMFFQGGETENEENLSSE----KAGLSGQADFDDFCS-SPGL 409
A + PL A AS AM + ++ L+S KA +SG+ S +PGL
Sbjct: 2374 AFN---PLNA--SASLPAAMPITAADGRSDHTLTSPGGGGKAKVSGRPSSRKAKSPAPGL 2428
Query: 410 G---RPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQ 466
RPP+ + V + C P VW D P ++GS L
Sbjct: 2429 ASGDRPPSVSSVHSEGDCNRRTP-----LTNRVWEDR-----PSSAGSTPFPYNPLIMRL 2478
Query: 467 NQEVLPSEPLNLDPSSPSDQFRYGPLPGP 495
V+ S P P P+ GPL GP
Sbjct: 2479 QAGVMASPP---PPGLPAGS---GPLAGP 2501
Score = 37.4 bits (85), Expect = 0.18
Identities = 40/163 (24%), Positives = 67/163 (41%), Gaps = 27/163 (16%)
Query: 1024 ASHPRQSGPGAPNLDRFYQQVTKDAQGQP-GLERAQQELVPPQQ--QASPPQLPKAMFSE 1080
A ++ P A + + + V +D + + G+ ++E+V + AS ++P+ E
Sbjct: 679 ARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRG---E 735
Query: 1081 LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPW 1140
S P ++ + S SP + D GQ P+PP A + ++ P
Sbjct: 736 CSGPATVNNSSDTE-SIPSPHTEAAKDTGQN-GPKPP--------------ATLGADGPP 779
Query: 1141 PQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGA 1183
P P P PPP+D+ A P +A P PP P A
Sbjct: 780 PGP-----PTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSA 817
Score = 36.2 bits (82), Expect = 0.39
Identities = 27/79 (34%), Positives = 29/79 (36%), Gaps = 18/79 (22%)
Query: 193 DGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCP------EGPV--------- 237
D T A P+ P P P P Q G P G+ RSP P E PV
Sbjct: 987 DAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEA 1046
Query: 238 ---PSGVPCATSVPHFPTP 253
P PC TS FP P
Sbjct: 1047 QKLPGDPPCWTSGLPFPVP 1065
Score = 35.4 bits (80), Expect = 0.67
Identities = 75/318 (23%), Positives = 109/318 (34%), Gaps = 66/318 (20%)
Query: 647 PAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEK 706
PA D P PP P+ P P TE GAP P+P
Sbjct: 770 PATLGADGPPPGPPTPP--------PEDIPAP----TEPTPASEATGAPTPPPAPPSPSA 817
Query: 707 RPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYV-CAKPQPPVVQP-PEEA 764
P + + E+ A P G PAA L V K + PV EEA
Sbjct: 818 PPPVVPKEEKEEETAAAP-------PVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEA 870
Query: 765 MSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQ 824
G + AA + G + A + + SG A+ S
Sbjct: 871 EEGPAKGKDAEAAEATAEGALKAEKK---------------EGGSGRATTAKSS------ 909
Query: 825 NPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTS 884
P S + A V + +KN+ L+ RP++ + GD N S
Sbjct: 910 ------GAPQDSDSSATCSADEVDEAEGGDKNR-----LLSPRPSLLTPT--GDPRANAS 956
Query: 885 LS---GIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPES 941
+ + ++P V + + P A+ +PA PP+ P P+NL PES
Sbjct: 957 PQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAP---TKPA-----PPAPPPPQNLQPES 1008
Query: 942 QKDRKAGSALPGFANSPA 959
++ GS+ G + SPA
Sbjct: 1009 DAPQQPGSSPRGKSRSPA 1026
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 59.7 bits (143), Expect = 3e-08
Identities = 66/251 (26%), Positives = 85/251 (33%), Gaps = 49/251 (19%)
Query: 42 APTTCPLQPVTDPFAFSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARD 101
AP P P P + A P GS + S P Q P VPHTH +
Sbjct: 200 APPGTPQLPTPGP---TPSATAVPPQGSPTASQAP--------NQPQAPTAPVPHTHIQQ 248
Query: 102 SS----QGPCEPLPGPLTQPRAHASPFSGAL-TPSAPPGPEMNRSAEVGPSSEPEVQTLP 156
+ Q P P P P P P +G+ PSAP + + GP +Q P
Sbjct: 249 APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ-GPPGPHSLQAGP 307
Query: 157 YLPHYIP----GVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMP 212
L H P G+ P+ S G P G P + + P LQ+P
Sbjct: 308 LLQHPGPPQPFGLPPQASQGQAPLGTSP--------------------AAAYPHTSLQLP 347
Query: 213 GQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGH-------EQH 265
+Q P Q P P P T +P P P H+ P H +
Sbjct: 348 ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMN 406
Query: 266 SPLVAPPAALP 276
+ L PPA P
Sbjct: 407 ANLPPPPALKP 417
Score = 58.5 bits (140), Expect = 7e-08
Identities = 106/394 (26%), Positives = 136/394 (34%), Gaps = 57/394 (14%)
Query: 1905 PGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLAS 1964
PGTP QL PG P A P P S + P P + P
Sbjct: 202 PGTP-----QLPTPG---PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 253
Query: 1965 PARVPMF---PVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEAR 2021
P R P P P P PL+P G A +P G P P + LLQ
Sbjct: 254 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 313
Query: 2022 SPDP-GIVPQ----EAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPT 2076
P P G+ PQ +AP+G S + + L S++ S+ PP P
Sbjct: 314 PPQPFGLPPQASQGQAPLGTSPAAA----YPHTSLQLPASQSALQSQQPPREQPLPPAPL 369
Query: 2077 QPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEK 2136
P + P P T P A + K P P A LP K
Sbjct: 370 AMP-HIKPPPTTPIPQLPAPQAHKHPPHLSG------PSPFSMNANLPPPPAL------K 416
Query: 2137 KNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDV 2196
++ + P A PPP MP++ Q P + PPG S+ A +
Sbjct: 417 PLSSLSTHHP---PSAHPPPLQLMPQS-QPLPSSPAQPPGL---TQSQNLPPPPASH--- 466
Query: 2197 LNPSGTQR--SEPALAPADFVAPLAPLPIPSNLFVPT-PDAEEPQLPDGTGREGP---AA 2250
P+G + +P A FV P P PI PT P P GT + P AA
Sbjct: 467 -PPTGLHQVAPQPPFAQHPFV-PGGPPPITP----PTCPSTSTPPAGPGTSAQPPCSGAA 520
Query: 2251 ARG--LANPEPAPEPKVLSSAASLPGSELPSSRP 2282
A G +A P P V +L +E P S P
Sbjct: 521 ASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP 554
Score = 43.5 bits (101), Expect = 0.002
Identities = 81/347 (23%), Positives = 114/347 (32%), Gaps = 46/347 (13%)
Query: 1849 VQMASQLRLFDPQLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTP 1908
+Q A L P P S P LQ + + + H L Q P P
Sbjct: 246 IQQAPALHPQRPPSPHPPPHPSPHPP-----LQPLTGSAGQPSAPSHAQPPLHGQGPPGP 300
Query: 1909 SSEMEQ--LDRPGLSQPGAL------GIANPLLAVPAPSPEHSSPSVRLLPSAPQT---- 1956
S L PG QP L G A PL PA + H+S + SA Q+
Sbjct: 301 HSLQAGPLLQHPGPPQPFGLPPQASQGQA-PLGTSPAAAYPHTSLQLPASQSALQSQQPP 359
Query: 1957 ----LPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGL----PPGVP 2008
LP PLA P + P P P P P P P L P PP +
Sbjct: 360 REQPLPPAPLAMPH---IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK 416
Query: 2009 PLQE-RRHLLQEARSPDPGIVPQEAPVGNSLSE----LSEENFDGKFANLTPSRTVPDSE 2063
PL H A P ++PQ P+ +S ++ +N A+ P+ +
Sbjct: 417 PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP 476
Query: 2064 APPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYL 2123
PP PP++ P T P + P G + + G
Sbjct: 477 QPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPT 536
Query: 2124 PDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPA 2170
K ++ L++ EE + PPPP + P+ P+
Sbjct: 537 VQIKEEA------------LDDAEEPESPPPPPRSPSPEPTVVDTPS 571
Score = 42.4 bits (98), Expect = 0.005
Identities = 54/231 (23%), Positives = 81/231 (35%), Gaps = 33/231 (14%)
Query: 1010 NPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQAS 1069
N S SDS A QQ + + P P L + PG + P A
Sbjct: 167 NESDSDSSAQQQMLQAQP-------PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV 219
Query: 1070 PPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGS 1129
PPQ + P++ A + Q+PA PP P + ++ +
Sbjct: 220 PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 279
Query: 1130 GQAAVPSEQPWPQPVPALAPGPP-PQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYY 1188
GQ + PS QP P GPP P L A P P PP+P
Sbjct: 280 GQPSAPSHA---QP-PLHGQGPPGPHSLQA-----------GPLLQHPGPPQP------- 317
Query: 1189 QDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYP 1239
+ L + ++ A Y + + P+S+++ S++PP Q P
Sbjct: 318 ---FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 365
Score = 40.0 bits (92), Expect = 0.027
Identities = 77/339 (22%), Positives = 111/339 (32%), Gaps = 69/339 (20%)
Query: 908 PQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLV 967
PQ + + S Q L QPP+ P + P LP +P + S V
Sbjct: 164 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP----TPGPTPSATAV 219
Query: 968 PPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHP 1027
PP + + + + + P + + P H Q +
Sbjct: 220 PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 279
Query: 1028 RQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESL 1087
Q P AP+ + Q QG PG Q P Q PPQ P L
Sbjct: 280 GQ--PSAPS----HAQPPLHGQGPPGPHSLQAG--PLLQHPGPPQ-----------PFGL 320
Query: 1088 PAQG-QAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPA 1146
P Q Q Q + + QLP + Q+A+ S+QP P+ P
Sbjct: 321 PPQASQGQAPLGTSPAAAYPHTSLQLP---------------ASQSALQSQQP-PREQPL 364
Query: 1147 LAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAA 1206
PP LA + P P +P P P A ++ P+
Sbjct: 365 -----PPAPLAMPHIKPP------PTTPIPQLPAPQAH-------------KHPPHLSGP 400
Query: 1207 SAYAQNYRYPEPE--RP-SSRASH--SSERPPPRQGYPE 1240
S ++ N P P +P SS ++H S PPP Q P+
Sbjct: 401 SPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 439
Score = 38.9 bits (89), Expect = 0.060
Identities = 61/276 (22%), Positives = 89/276 (32%), Gaps = 32/276 (11%)
Query: 895 SLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGF 954
S S+PS + S +M L QPP+ P + P LP
Sbjct: 158 SPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVTPAPSSAPPGTPQLP-- 208
Query: 955 ANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHS 1014
+P + S VPP + + + + + P + + P H
Sbjct: 209 --TPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP 266
Query: 1015 DSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQ-----QELVPPQQQAS 1069
Q + Q P AP+ + Q QG PG Q Q PPQ
Sbjct: 267 SPHPPLQPLTGSAGQ--PSAPS----HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 320
Query: 1070 PPQLPKAMFSELSNPES--------LPAQGQAQNSAQSPASLVLVDAGQQLPP-RPPQSS 1120
PPQ + ++P + LPA A S Q P L A +P +PP ++
Sbjct: 321 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 380
Query: 1121 SVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDL 1156
+ + + P P P A PPP L
Sbjct: 381 PIPQLPAPQAHKH-PPHLSGPSPFSMNANLPPPPAL 415
Score = 38.1 bits (87), Expect = 0.10
Identities = 102/454 (22%), Positives = 150/454 (33%), Gaps = 59/454 (12%)
Query: 393 GLSGQADFDDFCSSPGLGR-PPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDA 451
G +GQ P G+ PP P + AG L Q PGP + +
Sbjct: 277 GSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH--PGPPQPFGLPPQASQGQAPLGTS 334
Query: 452 SGSQYENVENLEFVQNQEVLPSE-PLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPD 510
+ Y + +L+ +Q L S+ P P P+ P P P + AP
Sbjct: 335 PAAAYPHT-SLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP----IPQLPAPQ 389
Query: 511 ATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSP 570
A H H S S +S ++ + +P + T P + + + SSP
Sbjct: 390 AHKHPPHL-SGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS-QPLPSSP 447
Query: 571 VGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRAN 630
+ T SQN P P+ PTG+ Q + F G P
Sbjct: 448 A--QPPGLTQSQNL------PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP--- 496
Query: 631 VVGEVRETCVRQKQCRPAAALPDASPGNLEQPP-----DNMETLCAPQVCPLP-LNSTTE 684
TC P+ + P A PG QPP + ++ CPLP + E
Sbjct: 497 -------TC-------PSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE 542
Query: 685 AVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAA 744
A+ +PP P+PE P+ V S A+ + D G N + A
Sbjct: 543 ALDDAEEPESPPPPPRSPSPE--PTV-----VDTPSHASQSARFYKHLDRGYN---SCAR 592
Query: 745 PALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQ 804
LY + + EEA+ + A + R E + E E
Sbjct: 593 TDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAA 652
Query: 805 SQASSGYASLLSSPPTE-------SLQNPPVLIA 831
+SS + LS P S + PP IA
Sbjct: 653 KASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIA 686
Score = 36.6 bits (83), Expect = 0.30
Identities = 95/391 (24%), Positives = 127/391 (32%), Gaps = 74/391 (18%)
Query: 429 PGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSD--- 485
P +E G+ + S V D S ++++ N+ PS P D S SD
Sbjct: 123 PNSPSEGEGE---SSDSRSVNDEGSSDPKDIDQ----DNRSTSPSIPSPQDNESDSDSSA 175
Query: 486 --QFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQE-- 541
Q P P + AP T P S+ + G + S P +
Sbjct: 176 QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ 235
Query: 542 -----LVGTFIQQEVGKPEDEASGSFFKQIDSSP-VGGETDETTVSQNYRGSVSQPSTPS 595
+ T IQQ + + Q SP Q GS QPS PS
Sbjct: 236 APTAPVPHTHIQQ---------APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPS 286
Query: 596 ---PP----KPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPA 648
PP P G A P+ H +PF G+ PA
Sbjct: 287 HAQPPLHGQGPPGPHSLQAG----PLLQHPGPPQPFGLPPQASQGQA------PLGTSPA 336
Query: 649 AALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTV--YPAPE- 705
AA P S L +++ P+ PLP A +PH PP + PAP+
Sbjct: 337 AAYPHTSL-QLPASQSALQSQQPPREQPLP-----PAPLAMPHIKPPPTTPIPQLPAPQA 390
Query: 706 -KRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEA 764
K P GP SP + N+ PA L + PP PP
Sbjct: 391 HKHP-PHLSGP----SPFS----------MNANLPPPPALKPLSSLSTHHPPSAHPPPLQ 435
Query: 765 MSGQQSRNPSSAAPVQSRGGIGASENLENPP 795
+ Q PSS A G+ S+NL PP
Sbjct: 436 LMPQSQPLPSSPA---QPPGLTQSQNLPPPP 463
Score = 33.5 bits (75), Expect = 2.5
Identities = 146/689 (21%), Positives = 216/689 (31%), Gaps = 165/689 (23%)
Query: 499 RHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEA 558
R G +PD ++ D SS +S S S + E V ++ K ++EA
Sbjct: 31 RSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETV----KKSAKKVKEEA 86
Query: 559 SGSF-FKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSH 617
S + V +T+E + + + + S P+ P G ++S + S S
Sbjct: 87 SSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESSDSRSVNDEGSS 145
Query: 618 LVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPL 677
P + D+ N R T + ++P SP + E D+ Q P
Sbjct: 146 ----DPKDIDQDN-----RST---------SPSIP--SPQDNESDSDSSAQQQMLQAQPP 185
Query: 678 PLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGN 737
L + T V P + APP P P PSA T P + A+ Q + P
Sbjct: 186 ALQAPT-GVTPAP-SSAPPGTPQLPTPGPTPSA-TAVPPQGSPTASQAPNQPQAPTAPVP 242
Query: 738 VLLAPAAPALYVCAKPQP-----PVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLE 792
APAL+ P P P PP + ++G + PS+ + Q
Sbjct: 243 HTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ-PSAPSHAQ------------ 289
Query: 793 NPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNS 852
PP L Q G SL + P + PP P + P+ S + +
Sbjct: 290 -PP-------LHGQGPPGPHSLQAGPLLQH-PGPPQPFGLPPQASQGQAPLGTSPAAAYP 340
Query: 853 HEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSG 912
H SL LP+S
Sbjct: 341 HT----------------------------------------SLQLPAS----------- 349
Query: 913 ASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHG 972
S + S QP P QP+P A A+P P + P AH
Sbjct: 350 QSALQSQQP------PREQPLPP-----------APLAMPHIKPPPTTPIPQLPAPQAH- 391
Query: 973 TLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGP 1032
H G F+++ L P + S SL++ ++HP
Sbjct: 392 ------------KHPPHLSGPSPFSMNANLPPPPALKPLS---SLSTHHPPSAHP----- 431
Query: 1033 GAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQ 1092
P L+ Q P A PP L ++ + P S P G
Sbjct: 432 -------------------PPLQLMPQSQPLPSSPAQPPGLTQSQ-NLPPPPASHPPTGL 471
Query: 1093 AQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPP 1152
Q + Q P + G P PP S S +G G +A P ++A G
Sbjct: 472 HQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS 531
Query: 1153 PQDLAAYYYYRPLYDAYQPQYSLPYPPEP 1181
L DA +P+ P P P
Sbjct: 532 CPLPTVQIKEEALDDAEEPESPPPPPRSP 560
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 59.7 bits (143), Expect = 3e-08
Identities = 66/251 (26%), Positives = 85/251 (33%), Gaps = 49/251 (19%)
Query: 42 APTTCPLQPVTDPFAFSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARD 101
AP P P P + A P GS + S P Q P VPHTH +
Sbjct: 754 APPGTPQLPTPGP---TPSATAVPPQGSPTASQAP--------NQPQAPTAPVPHTHIQQ 802
Query: 102 SS----QGPCEPLPGPLTQPRAHASPFSGAL-TPSAPPGPEMNRSAEVGPSSEPEVQTLP 156
+ Q P P P P P P +G+ PSAP + + GP +Q P
Sbjct: 803 APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ-GPPGPHSLQAGP 861
Query: 157 YLPHYIP----GVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMP 212
L H P G+ P+ S G P G P + + P LQ+P
Sbjct: 862 LLQHPGPPQPFGLPPQASQGQAPLGTSP--------------------AAAYPHTSLQLP 901
Query: 213 GQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGH-------EQH 265
+Q P Q P P P T +P P P H+ P H +
Sbjct: 902 ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMN 960
Query: 266 SPLVAPPAALP 276
+ L PPA P
Sbjct: 961 ANLPPPPALKP 971
Score = 58.5 bits (140), Expect = 7e-08
Identities = 106/394 (26%), Positives = 136/394 (34%), Gaps = 57/394 (14%)
Query: 1905 PGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLAS 1964
PGTP QL PG P A P P S + P P + P
Sbjct: 756 PGTP-----QLPTPG---PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807
Query: 1965 PARVPMF---PVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEAR 2021
P R P P P P PL+P G A +P G P P + LLQ
Sbjct: 808 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 867
Query: 2022 SPDP-GIVPQ----EAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPT 2076
P P G+ PQ +AP+G S + + L S++ S+ PP P
Sbjct: 868 PPQPFGLPPQASQGQAPLGTSPAAA----YPHTSLQLPASQSALQSQQPPREQPLPPAPL 923
Query: 2077 QPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEK 2136
P + P P T P A + K P P A LP K
Sbjct: 924 AMP-HIKPPPTTPIPQLPAPQAHKHPPHLSG------PSPFSMNANLPPPPAL------K 970
Query: 2137 KNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDV 2196
++ + P A PPP MP++ Q P + PPG S+ A +
Sbjct: 971 PLSSLSTHHP---PSAHPPPLQLMPQS-QPLPSSPAQPPGL---TQSQNLPPPPASH--- 1020
Query: 2197 LNPSGTQR--SEPALAPADFVAPLAPLPIPSNLFVPT-PDAEEPQLPDGTGREGP---AA 2250
P+G + +P A FV P P PI PT P P GT + P AA
Sbjct: 1021 -PPTGLHQVAPQPPFAQHPFV-PGGPPPITP----PTCPSTSTPPAGPGTSAQPPCSGAA 1074
Query: 2251 ARG--LANPEPAPEPKVLSSAASLPGSELPSSRP 2282
A G +A P P V +L +E P S P
Sbjct: 1075 ASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP 1108
Score = 43.5 bits (101), Expect = 0.002
Identities = 81/347 (23%), Positives = 114/347 (32%), Gaps = 46/347 (13%)
Query: 1849 VQMASQLRLFDPQLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTP 1908
+Q A L P P S P LQ + + + H L Q P P
Sbjct: 800 IQQAPALHPQRPPSPHPPPHPSPHPP-----LQPLTGSAGQPSAPSHAQPPLHGQGPPGP 854
Query: 1909 SSEMEQ--LDRPGLSQPGAL------GIANPLLAVPAPSPEHSSPSVRLLPSAPQT---- 1956
S L PG QP L G A PL PA + H+S + SA Q+
Sbjct: 855 HSLQAGPLLQHPGPPQPFGLPPQASQGQA-PLGTSPAAAYPHTSLQLPASQSALQSQQPP 913
Query: 1957 ----LPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGL----PPGVP 2008
LP PLA P + P P P P P P P L P PP +
Sbjct: 914 REQPLPPAPLAMPH---IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK 970
Query: 2009 PLQE-RRHLLQEARSPDPGIVPQEAPVGNSLSE----LSEENFDGKFANLTPSRTVPDSE 2063
PL H A P ++PQ P+ +S ++ +N A+ P+ +
Sbjct: 971 PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP 1030
Query: 2064 APPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYL 2123
PP PP++ P T P + P G + + G
Sbjct: 1031 QPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPT 1090
Query: 2124 PDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPA 2170
K ++ L++ EE + PPPP + P+ P+
Sbjct: 1091 VQIKEEA------------LDDAEEPESPPPPPRSPSPEPTVVDTPS 1125
Score = 42.4 bits (98), Expect = 0.005
Identities = 54/231 (23%), Positives = 81/231 (35%), Gaps = 33/231 (14%)
Query: 1010 NPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQAS 1069
N S SDS A QQ + + P P L + PG + P A
Sbjct: 721 NESDSDSSAQQQMLQAQP-------PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV 773
Query: 1070 PPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGS 1129
PPQ + P++ A + Q+PA PP P + ++ +
Sbjct: 774 PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 833
Query: 1130 GQAAVPSEQPWPQPVPALAPGPP-PQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYY 1188
GQ + PS QP P GPP P L A P P PP+P
Sbjct: 834 GQPSAPSHA---QP-PLHGQGPPGPHSLQA-----------GPLLQHPGPPQP------- 871
Query: 1189 QDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYP 1239
+ L + ++ A Y + + P+S+++ S++PP Q P
Sbjct: 872 ---FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 919
Score = 40.0 bits (92), Expect = 0.027
Identities = 77/339 (22%), Positives = 111/339 (32%), Gaps = 69/339 (20%)
Query: 908 PQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLV 967
PQ + + S Q L QPP+ P + P LP +P + S V
Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP----TPGPTPSATAV 773
Query: 968 PPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHP 1027
PP + + + + + P + + P H Q +
Sbjct: 774 PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 833
Query: 1028 RQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESL 1087
Q P AP+ + Q QG PG Q P Q PPQ P L
Sbjct: 834 GQ--PSAPS----HAQPPLHGQGPPGPHSLQAG--PLLQHPGPPQ-----------PFGL 874
Query: 1088 PAQG-QAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPA 1146
P Q Q Q + + QLP + Q+A+ S+QP P+ P
Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLP---------------ASQSALQSQQP-PREQPL 918
Query: 1147 LAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAA 1206
PP LA + P P +P P P A ++ P+
Sbjct: 919 -----PPAPLAMPHIKPP------PTTPIPQLPAPQAH-------------KHPPHLSGP 954
Query: 1207 SAYAQNYRYPEPE--RP-SSRASH--SSERPPPRQGYPE 1240
S ++ N P P +P SS ++H S PPP Q P+
Sbjct: 955 SPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 993
Score = 38.9 bits (89), Expect = 0.060
Identities = 61/276 (22%), Positives = 89/276 (32%), Gaps = 32/276 (11%)
Query: 895 SLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGF 954
S S+PS + S +M L QPP+ P + P LP
Sbjct: 712 SPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVTPAPSSAPPGTPQLP-- 762
Query: 955 ANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHS 1014
+P + S VPP + + + + + P + + P H
Sbjct: 763 --TPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP 820
Query: 1015 DSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQ-----QELVPPQQQAS 1069
Q + Q P AP+ + Q QG PG Q Q PPQ
Sbjct: 821 SPHPPLQPLTGSAGQ--PSAPS----HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 874
Query: 1070 PPQLPKAMFSELSNPES--------LPAQGQAQNSAQSPASLVLVDAGQQLPP-RPPQSS 1120
PPQ + ++P + LPA A S Q P L A +P +PP ++
Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 934
Query: 1121 SVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDL 1156
+ + + P P P A PPP L
Sbjct: 935 PIPQLPAPQAHKH-PPHLSGPSPFSMNANLPPPPAL 969
Score = 38.1 bits (87), Expect = 0.10
Identities = 102/454 (22%), Positives = 150/454 (33%), Gaps = 59/454 (12%)
Query: 393 GLSGQADFDDFCSSPGLGR-PPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDA 451
G +GQ P G+ PP P + AG L Q PGP + +
Sbjct: 831 GSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH--PGPPQPFGLPPQASQGQAPLGTS 888
Query: 452 SGSQYENVENLEFVQNQEVLPSE-PLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPD 510
+ Y + +L+ +Q L S+ P P P+ P P P + AP
Sbjct: 889 PAAAYPHT-SLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP----IPQLPAPQ 943
Query: 511 ATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSP 570
A H H S S +S ++ + +P + T P + + + SSP
Sbjct: 944 AHKHPPHL-SGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS-QPLPSSP 1001
Query: 571 VGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRAN 630
+ T SQN P P+ PTG+ Q + F G P
Sbjct: 1002 A--QPPGLTQSQNL------PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP--- 1050
Query: 631 VVGEVRETCVRQKQCRPAAALPDASPGNLEQPP-----DNMETLCAPQVCPLP-LNSTTE 684
TC P+ + P A PG QPP + ++ CPLP + E
Sbjct: 1051 -------TC-------PSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE 1096
Query: 685 AVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAA 744
A+ +PP P+PE P+ V S A+ + D G N + A
Sbjct: 1097 ALDDAEEPESPPPPPRSPSPE--PTV-----VDTPSHASQSARFYKHLDRGYN---SCAR 1146
Query: 745 PALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQ 804
LY + + EEA+ + A + R E + E E
Sbjct: 1147 TDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAA 1206
Query: 805 SQASSGYASLLSSPPTE-------SLQNPPVLIA 831
+SS + LS P S + PP IA
Sbjct: 1207 KASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIA 1240
Score = 36.6 bits (83), Expect = 0.30
Identities = 95/391 (24%), Positives = 127/391 (32%), Gaps = 74/391 (18%)
Query: 429 PGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSD--- 485
P +E G+ + S V D S ++++ N+ PS P D S SD
Sbjct: 677 PNSPSEGEGE---SSDSRSVNDEGSSDPKDIDQ----DNRSTSPSIPSPQDNESDSDSSA 729
Query: 486 --QFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQE-- 541
Q P P + AP T P S+ + G + S P +
Sbjct: 730 QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ 789
Query: 542 -----LVGTFIQQEVGKPEDEASGSFFKQIDSSP-VGGETDETTVSQNYRGSVSQPSTPS 595
+ T IQQ + + Q SP Q GS QPS PS
Sbjct: 790 APTAPVPHTHIQQ---------APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPS 840
Query: 596 ---PP----KPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPA 648
PP P G A P+ H +PF G+ PA
Sbjct: 841 HAQPPLHGQGPPGPHSLQAG----PLLQHPGPPQPFGLPPQASQGQA------PLGTSPA 890
Query: 649 AALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTV--YPAPE- 705
AA P S L +++ P+ PLP A +PH PP + PAP+
Sbjct: 891 AAYPHTSL-QLPASQSALQSQQPPREQPLP-----PAPLAMPHIKPPPTTPIPQLPAPQA 944
Query: 706 -KRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEA 764
K P GP SP + N+ PA L + PP PP
Sbjct: 945 HKHP-PHLSGP----SPFS----------MNANLPPPPALKPLSSLSTHHPPSAHPPPLQ 989
Query: 765 MSGQQSRNPSSAAPVQSRGGIGASENLENPP 795
+ Q PSS A G+ S+NL PP
Sbjct: 990 LMPQSQPLPSSPA---QPPGLTQSQNLPPPP 1017
Score = 33.5 bits (75), Expect = 2.5
Identities = 146/689 (21%), Positives = 216/689 (31%), Gaps = 165/689 (23%)
Query: 499 RHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEA 558
R G +PD ++ D SS +S S S + E V ++ K ++EA
Sbjct: 585 RSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETV----KKSAKKVKEEA 640
Query: 559 SGSF-FKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSH 617
S + V +T+E + + + + S P+ P G ++S + S S
Sbjct: 641 SSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESSDSRSVNDEGSS 699
Query: 618 LVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPL 677
P + D+ N R T + ++P SP + E D+ Q P
Sbjct: 700 ----DPKDIDQDN-----RST---------SPSIP--SPQDNESDSDSSAQQQMLQAQPP 739
Query: 678 PLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGN 737
L + T V P + APP P P PSA T P + A+ Q + P
Sbjct: 740 ALQAPT-GVTPAP-SSAPPGTPQLPTPGPTPSA-TAVPPQGSPTASQAPNQPQAPTAPVP 796
Query: 738 VLLAPAAPALYVCAKPQP-----PVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLE 792
APAL+ P P P PP + ++G + PS+ + Q
Sbjct: 797 HTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ-PSAPSHAQ------------ 843
Query: 793 NPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNS 852
PP L Q G SL + P + PP P + P+ S + +
Sbjct: 844 -PP-------LHGQGPPGPHSLQAGPLLQH-PGPPQPFGLPPQASQGQAPLGTSPAAAYP 894
Query: 853 HEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSG 912
H SL LP+S
Sbjct: 895 HT----------------------------------------SLQLPAS----------- 903
Query: 913 ASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHG 972
S + S QP P QP+P A A+P P + P AH
Sbjct: 904 QSALQSQQP------PREQPLPP-----------APLAMPHIKPPPTTPIPQLPAPQAH- 945
Query: 973 TLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGP 1032
H G F+++ L P + S SL++ ++HP
Sbjct: 946 ------------KHPPHLSGPSPFSMNANLPPPPALKPLS---SLSTHHPPSAHP----- 985
Query: 1033 GAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQ 1092
P L+ Q P A PP L ++ + P S P G
Sbjct: 986 -------------------PPLQLMPQSQPLPSSPAQPPGLTQSQ-NLPPPPASHPPTGL 1025
Query: 1093 AQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPP 1152
Q + Q P + G P PP S S +G G +A P ++A G
Sbjct: 1026 HQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS 1085
Query: 1153 PQDLAAYYYYRPLYDAYQPQYSLPYPPEP 1181
L DA +P+ P P P
Sbjct: 1086 CPLPTVQIKEEALDDAEEPESPPPPPRSP 1114
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 59.7 bits (143), Expect = 3e-08
Identities = 66/251 (26%), Positives = 85/251 (33%), Gaps = 49/251 (19%)
Query: 42 APTTCPLQPVTDPFAFSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARD 101
AP P P P + A P GS + S P Q P VPHTH +
Sbjct: 754 APPGTPQLPTPGP---TPSATAVPPQGSPTASQAP--------NQPQAPTAPVPHTHIQQ 802
Query: 102 SS----QGPCEPLPGPLTQPRAHASPFSGAL-TPSAPPGPEMNRSAEVGPSSEPEVQTLP 156
+ Q P P P P P P +G+ PSAP + + GP +Q P
Sbjct: 803 APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ-GPPGPHSLQAGP 861
Query: 157 YLPHYIP----GVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMP 212
L H P G+ P+ S G P G P + + P LQ+P
Sbjct: 862 LLQHPGPPQPFGLPPQASQGQAPLGTSP--------------------AAAYPHTSLQLP 901
Query: 213 GQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGH-------EQH 265
+Q P Q P P P T +P P P H+ P H +
Sbjct: 902 ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMN 960
Query: 266 SPLVAPPAALP 276
+ L PPA P
Sbjct: 961 ANLPPPPALKP 971
Score = 58.5 bits (140), Expect = 7e-08
Identities = 106/394 (26%), Positives = 136/394 (34%), Gaps = 57/394 (14%)
Query: 1905 PGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLAS 1964
PGTP QL PG P A P P S + P P + P
Sbjct: 756 PGTP-----QLPTPG---PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807
Query: 1965 PARVPMF---PVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEAR 2021
P R P P P P PL+P G A +P G P P + LLQ
Sbjct: 808 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG 867
Query: 2022 SPDP-GIVPQ----EAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPT 2076
P P G+ PQ +AP+G S + + L S++ S+ PP P
Sbjct: 868 PPQPFGLPPQASQGQAPLGTSPAAA----YPHTSLQLPASQSALQSQQPPREQPLPPAPL 923
Query: 2077 QPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEK 2136
P + P P T P A + K P P A LP K
Sbjct: 924 AMP-HIKPPPTTPIPQLPAPQAHKHPPHLSG------PSPFSMNANLPPPPAL------K 970
Query: 2137 KNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDV 2196
++ + P A PPP MP++ Q P + PPG S+ A +
Sbjct: 971 PLSSLSTHHP---PSAHPPPLQLMPQS-QPLPSSPAQPPGL---TQSQNLPPPPASH--- 1020
Query: 2197 LNPSGTQR--SEPALAPADFVAPLAPLPIPSNLFVPT-PDAEEPQLPDGTGREGP---AA 2250
P+G + +P A FV P P PI PT P P GT + P AA
Sbjct: 1021 -PPTGLHQVAPQPPFAQHPFV-PGGPPPITP----PTCPSTSTPPAGPGTSAQPPCSGAA 1074
Query: 2251 ARG--LANPEPAPEPKVLSSAASLPGSELPSSRP 2282
A G +A P P V +L +E P S P
Sbjct: 1075 ASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP 1108
Score = 43.5 bits (101), Expect = 0.002
Identities = 81/347 (23%), Positives = 114/347 (32%), Gaps = 46/347 (13%)
Query: 1849 VQMASQLRLFDPQLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTP 1908
+Q A L P P S P LQ + + + H L Q P P
Sbjct: 800 IQQAPALHPQRPPSPHPPPHPSPHPP-----LQPLTGSAGQPSAPSHAQPPLHGQGPPGP 854
Query: 1909 SSEMEQ--LDRPGLSQPGAL------GIANPLLAVPAPSPEHSSPSVRLLPSAPQT---- 1956
S L PG QP L G A PL PA + H+S + SA Q+
Sbjct: 855 HSLQAGPLLQHPGPPQPFGLPPQASQGQA-PLGTSPAAAYPHTSLQLPASQSALQSQQPP 913
Query: 1957 ----LPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGL----PPGVP 2008
LP PLA P + P P P P P P P L P PP +
Sbjct: 914 REQPLPPAPLAMPH---IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK 970
Query: 2009 PLQE-RRHLLQEARSPDPGIVPQEAPVGNSLSE----LSEENFDGKFANLTPSRTVPDSE 2063
PL H A P ++PQ P+ +S ++ +N A+ P+ +
Sbjct: 971 PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP 1030
Query: 2064 APPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYL 2123
PP PP++ P T P + P G + + G
Sbjct: 1031 QPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPT 1090
Query: 2124 PDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAPPA 2170
K ++ L++ EE + PPPP + P+ P+
Sbjct: 1091 VQIKEEA------------LDDAEEPESPPPPPRSPSPEPTVVDTPS 1125
Score = 42.4 bits (98), Expect = 0.005
Identities = 54/231 (23%), Positives = 81/231 (35%), Gaps = 33/231 (14%)
Query: 1010 NPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQAS 1069
N S SDS A QQ + + P P L + PG + P A
Sbjct: 721 NESDSDSSAQQQMLQAQP-------PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV 773
Query: 1070 PPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGS 1129
PPQ + P++ A + Q+PA PP P + ++ +
Sbjct: 774 PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 833
Query: 1130 GQAAVPSEQPWPQPVPALAPGPP-PQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYY 1188
GQ + PS QP P GPP P L A P P PP+P
Sbjct: 834 GQPSAPSHA---QP-PLHGQGPPGPHSLQA-----------GPLLQHPGPPQP------- 871
Query: 1189 QDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYP 1239
+ L + ++ A Y + + P+S+++ S++PP Q P
Sbjct: 872 ---FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 919
Score = 40.0 bits (92), Expect = 0.027
Identities = 77/339 (22%), Positives = 111/339 (32%), Gaps = 69/339 (20%)
Query: 908 PQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLV 967
PQ + + S Q L QPP+ P + P LP +P + S V
Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP----TPGPTPSATAV 773
Query: 968 PPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHP 1027
PP + + + + + P + + P H Q +
Sbjct: 774 PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 833
Query: 1028 RQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESL 1087
Q P AP+ + Q QG PG Q P Q PPQ P L
Sbjct: 834 GQ--PSAPS----HAQPPLHGQGPPGPHSLQAG--PLLQHPGPPQ-----------PFGL 874
Query: 1088 PAQG-QAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPA 1146
P Q Q Q + + QLP + Q+A+ S+QP P+ P
Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLP---------------ASQSALQSQQP-PREQPL 918
Query: 1147 LAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAA 1206
PP LA + P P +P P P A ++ P+
Sbjct: 919 -----PPAPLAMPHIKPP------PTTPIPQLPAPQAH-------------KHPPHLSGP 954
Query: 1207 SAYAQNYRYPEPE--RP-SSRASH--SSERPPPRQGYPE 1240
S ++ N P P +P SS ++H S PPP Q P+
Sbjct: 955 SPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 993
Score = 38.9 bits (89), Expect = 0.060
Identities = 61/276 (22%), Positives = 89/276 (32%), Gaps = 32/276 (11%)
Query: 895 SLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGF 954
S S+PS + S +M L QPP+ P + P LP
Sbjct: 712 SPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVTPAPSSAPPGTPQLP-- 762
Query: 955 ANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHS 1014
+P + S VPP + + + + + P + + P H
Sbjct: 763 --TPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP 820
Query: 1015 DSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQ-----QELVPPQQQAS 1069
Q + Q P AP+ + Q QG PG Q Q PPQ
Sbjct: 821 SPHPPLQPLTGSAGQ--PSAPS----HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 874
Query: 1070 PPQLPKAMFSELSNPES--------LPAQGQAQNSAQSPASLVLVDAGQQLPP-RPPQSS 1120
PPQ + ++P + LPA A S Q P L A +P +PP ++
Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 934
Query: 1121 SVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDL 1156
+ + + P P P A PPP L
Sbjct: 935 PIPQLPAPQAHKH-PPHLSGPSPFSMNANLPPPPAL 969
Score = 38.1 bits (87), Expect = 0.10
Identities = 102/454 (22%), Positives = 150/454 (33%), Gaps = 59/454 (12%)
Query: 393 GLSGQADFDDFCSSPGLGR-PPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDA 451
G +GQ P G+ PP P + AG L Q PGP + +
Sbjct: 831 GSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH--PGPPQPFGLPPQASQGQAPLGTS 888
Query: 452 SGSQYENVENLEFVQNQEVLPSE-PLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPD 510
+ Y + +L+ +Q L S+ P P P+ P P P + AP
Sbjct: 889 PAAAYPHT-SLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP----IPQLPAPQ 943
Query: 511 ATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSP 570
A H H S S +S ++ + +P + T P + + + SSP
Sbjct: 944 AHKHPPHL-SGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS-QPLPSSP 1001
Query: 571 VGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRAN 630
+ T SQN P P+ PTG+ Q + F G P
Sbjct: 1002 A--QPPGLTQSQNL------PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP--- 1050
Query: 631 VVGEVRETCVRQKQCRPAAALPDASPGNLEQPP-----DNMETLCAPQVCPLP-LNSTTE 684
TC P+ + P A PG QPP + ++ CPLP + E
Sbjct: 1051 -------TC-------PSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEE 1096
Query: 685 AVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAA 744
A+ +PP P+PE P+ V S A+ + D G N + A
Sbjct: 1097 ALDDAEEPESPPPPPRSPSPE--PTV-----VDTPSHASQSARFYKHLDRGYN---SCAR 1146
Query: 745 PALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQ 804
LY + + EEA+ + A + R E + E E
Sbjct: 1147 TDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAA 1206
Query: 805 SQASSGYASLLSSPPTE-------SLQNPPVLIA 831
+SS + LS P S + PP IA
Sbjct: 1207 KASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIA 1240
Score = 36.6 bits (83), Expect = 0.30
Identities = 95/391 (24%), Positives = 127/391 (32%), Gaps = 74/391 (18%)
Query: 429 PGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSD--- 485
P +E G+ + S V D S ++++ N+ PS P D S SD
Sbjct: 677 PNSPSEGEGE---SSDSRSVNDEGSSDPKDIDQ----DNRSTSPSIPSPQDNESDSDSSA 729
Query: 486 --QFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQE-- 541
Q P P + AP T P S+ + G + S P +
Sbjct: 730 QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQ 789
Query: 542 -----LVGTFIQQEVGKPEDEASGSFFKQIDSSP-VGGETDETTVSQNYRGSVSQPSTPS 595
+ T IQQ + + Q SP Q GS QPS PS
Sbjct: 790 APTAPVPHTHIQQ---------APALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPS 840
Query: 596 ---PP----KPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPA 648
PP P G A P+ H +PF G+ PA
Sbjct: 841 HAQPPLHGQGPPGPHSLQAG----PLLQHPGPPQPFGLPPQASQGQA------PLGTSPA 890
Query: 649 AALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTV--YPAPE- 705
AA P S L +++ P+ PLP A +PH PP + PAP+
Sbjct: 891 AAYPHTSL-QLPASQSALQSQQPPREQPLP-----PAPLAMPHIKPPPTTPIPQLPAPQA 944
Query: 706 -KRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEA 764
K P GP SP + N+ PA L + PP PP
Sbjct: 945 HKHP-PHLSGP----SPFS----------MNANLPPPPALKPLSSLSTHHPPSAHPPPLQ 989
Query: 765 MSGQQSRNPSSAAPVQSRGGIGASENLENPP 795
+ Q PSS A G+ S+NL PP
Sbjct: 990 LMPQSQPLPSSPA---QPPGLTQSQNLPPPP 1017
Score = 33.5 bits (75), Expect = 2.5
Identities = 146/689 (21%), Positives = 216/689 (31%), Gaps = 165/689 (23%)
Query: 499 RHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEA 558
R G +PD ++ D SS +S S S + E V ++ K ++EA
Sbjct: 585 RSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETV----KKSAKKVKEEA 640
Query: 559 SGSF-FKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSH 617
S + V +T+E + + + + S P+ P G ++S + S S
Sbjct: 641 SSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE-GEGESSDSRSVNDEGSS 699
Query: 618 LVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPL 677
P + D+ N R T + ++P SP + E D+ Q P
Sbjct: 700 ----DPKDIDQDN-----RST---------SPSIP--SPQDNESDSDSSAQQQMLQAQPP 739
Query: 678 PLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGN 737
L + T V P + APP P P PSA T P + A+ Q + P
Sbjct: 740 ALQAPT-GVTPAP-SSAPPGTPQLPTPGPTPSA-TAVPPQGSPTASQAPNQPQAPTAPVP 796
Query: 738 VLLAPAAPALYVCAKPQP-----PVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLE 792
APAL+ P P P PP + ++G + PS+ + Q
Sbjct: 797 HTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ-PSAPSHAQ------------ 843
Query: 793 NPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNS 852
PP L Q G SL + P + PP P + P+ S + +
Sbjct: 844 -PP-------LHGQGPPGPHSLQAGPLLQH-PGPPQPFGLPPQASQGQAPLGTSPAAAYP 894
Query: 853 HEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSG 912
H SL LP+S
Sbjct: 895 HT----------------------------------------SLQLPAS----------- 903
Query: 913 ASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHG 972
S + S QP P QP+P A A+P P + P AH
Sbjct: 904 QSALQSQQP------PREQPLPP-----------APLAMPHIKPPPTTPIPQLPAPQAH- 945
Query: 973 TLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGP 1032
H G F+++ L P + S SL++ ++HP
Sbjct: 946 ------------KHPPHLSGPSPFSMNANLPPPPALKPLS---SLSTHHPPSAHP----- 985
Query: 1033 GAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQ 1092
P L+ Q P A PP L ++ + P S P G
Sbjct: 986 -------------------PPLQLMPQSQPLPSSPAQPPGLTQSQ-NLPPPPASHPPTGL 1025
Query: 1093 AQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPP 1152
Q + Q P + G P PP S S +G G +A P ++A G
Sbjct: 1026 HQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS 1085
Query: 1153 PQDLAAYYYYRPLYDAYQPQYSLPYPPEP 1181
L DA +P+ P P P
Sbjct: 1086 CPLPTVQIKEEALDDAEEPESPPPPPRSP 1114
>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
sapiens]
Length = 1386
Score = 59.3 bits (142), Expect = 4e-08
Identities = 112/445 (25%), Positives = 159/445 (35%), Gaps = 53/445 (11%)
Query: 1942 HSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGP 2001
H + S P+ +G + +R PM P P L P + EP G
Sbjct: 924 HYTASFAYTPAVSFPHSEGLSGASSRPPMGLGPAPYSWL--ADSWPHPSRSPSAQEPRGS 981
Query: 2002 GLPPGVPP----LQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEE--NFDGKFANLTP 2055
P P E L A++ P E PV +++ EE F G F
Sbjct: 982 CCPSNPDPDDRYYNEAGISLYLAQTARGTAAPGEGPVYSTIDPAGEELQTFHGGFPQHPS 1041
Query: 2056 SRTVPDSE-APPGWDRADSG-----------PTQPPLSLSPAPETKRPGQAAKKETKEPK 2103
P S+ APP W + DSG P Q P SL+ P + + E
Sbjct: 1042 GDLGPWSQYAPPEWSQGDSGAKGGKVKLLGKPVQMP-SLNWPEALPPPPPSCELSCLEGP 1100
Query: 2104 KGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKT 2163
+ E L G + E + P +S + + + + E P P P+ ++
Sbjct: 1101 EEE------LEGSSEPEEWCPPMPERSHLTEPSSSGGCLVTPSRRE--TPSPTPSYGQQS 1152
Query: 2164 VQAAPPALPGPPGAPVNM-----YSRRAAGTRARYVDVLNPS-GTQRSEPA-LAPADFVA 2216
P+ P PP P +M RR + + V P G + + PA L +
Sbjct: 1153 TATLTPSPPDPPQPPTDMPHLHQMPRRVPLGPSSPLSVSQPMLGIREARPAGLGAGPAAS 1212
Query: 2217 P-LAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAA----ARGLANPEPAPEPKVLSSAAS 2271
P L+P P PS T + + G G P AR P+ P + +S
Sbjct: 1213 PHLSPSPAPS-----TASSAPGRTWQGNGEMTPPLQGPRARFRKKPKALPYRRE-NSPGD 1266
Query: 2272 LPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAG----GPPSGA-MP 2326
LP LP E S EL SMSSL RE S +A +P A P A +P
Sbjct: 1267 LPPPPLPPPEEEASWALELRAAGSMSSLERERSGE-RKAVQAVPLAAQRVLHPDEEAWLP 1325
Query: 2327 FYNPAQLAQACATSGSSRLGRIGQR 2351
+ P+ L++ TS S G R
Sbjct: 1326 YSRPSFLSRGQGTSTCSTAGSNSSR 1350
Score = 31.6 bits (70), Expect = 9.6
Identities = 43/191 (22%), Positives = 62/191 (32%), Gaps = 49/191 (25%)
Query: 1067 QASPPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVS 1126
+A PP P S L PE + + S++ ++ P P+ S ++ S
Sbjct: 1083 EALPPPPPSCELSCLEGPEE-----ELEGSSEP----------EEWCPPMPERSHLTEPS 1127
Query: 1127 SGSGQAAVPSEQPWPQPVPA--------LAPGPPPQDLAAYYYYRPLYDAYQPQYSLPY- 1177
S G PS + P P P+ L P PP D QP +P+
Sbjct: 1128 SSGGCLVTPSRRETPSPTPSYGQQSTATLTPSPP--------------DPPQPPTDMPHL 1173
Query: 1178 -------PPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASH--- 1227
P P + Q + + E R +A P P SS
Sbjct: 1174 HQMPRRVPLGPSSPLSVSQPMLGIREARPAGLGAGPAASPHLSPSPAPSTASSAPGRTWQ 1233
Query: 1228 -SSERPPPRQG 1237
+ E PP QG
Sbjct: 1234 GNGEMTPPLQG 1244
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 58.5 bits (140), Expect = 7e-08
Identities = 86/307 (28%), Positives = 107/307 (34%), Gaps = 76/307 (24%)
Query: 2 QPPPQTVPSGMAGPPPAGNPR-SVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 60
Q PPQ A PP A P+ S ASSP + + PT Q F +
Sbjct: 645 QQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQER 704
Query: 61 ALQSTPLGSSSK----------SSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPL 110
+ Q PL + S+PP Q PAPA A+ + GP
Sbjct: 705 SQQ--PLSAEGPHLSVPASVIVSAPPPAQDPAPAT-----------PVAKGAGLGP---- 747
Query: 111 PGPLTQPRAHASPFSGALTPSAPP--GPEMNRSAEVGPSSEPEVQTLPYLPHYIP-GVDP 167
P + ASP P+A P GP GPSS P LPH P G P
Sbjct: 748 ----QAPDSQASPAPAPQIPAAAPLKGP--------GPSSSPS------LPHQAPLGDSP 789
Query: 168 E--TSHGGHPHGNMPGLDRPLSR---QNPHDGVVTPAASPSLP-----------QPGLQM 211
+ H P P + +SR + P P A P+LP P
Sbjct: 790 HLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASN 849
Query: 212 PGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAP 271
P P G PQP + +S PEGP+P PH P S + S +
Sbjct: 850 PAPTAP--GPPQPPLRPQSQPPEGPLP-------PAPHLPPSSTSSAVASSSETSSRL-- 898
Query: 272 PAALPSD 278
PA PSD
Sbjct: 899 PAPTPSD 905
Score = 57.0 bits (136), Expect = 2e-07
Identities = 106/424 (25%), Positives = 151/424 (35%), Gaps = 73/424 (17%)
Query: 1900 LPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPD 1959
LPQ+ P S + P LS P ++ ++ P PA P ++P + PQ PD
Sbjct: 700 LPQERSQQPLSA----EGPHLSVPASVIVSAP---PPAQDPAPATPVAKGAGLGPQA-PD 751
Query: 1960 GPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQE 2019
ASPA P P P PGP+ S P LP P L + HL
Sbjct: 752 SQ-ASPAPAPQIPAAAP---------LKGPGPS------SSPSLPHQAP-LGDSPHL--- 791
Query: 2020 ARSPDPGIVPQEAPVG-NSLSELSEENFDGKFANLTPSRTVPDSEAPP---GWDRADSGP 2075
SP P P P S+S E P P +APP G +
Sbjct: 792 -PSPHPTRPPSRPPSRPQSVSRPPSE---------PPLHPCPPPQAPPTLPGIFVIQNQL 841
Query: 2076 TQPPLSLSPAPETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDE 2135
PP + +PAP P Q + +P +G LP + A + S +
Sbjct: 842 GVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP 901
Query: 2136 KKNQWVNLNEPEE----------------EKKAPPPPPTSMPKTVQAAPPALPGPPGAPV 2179
+ + P + E APPPPP + V PALP P A +
Sbjct: 902 TPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALP-QPKALL 960
Query: 2180 NMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEE--P 2237
+ + +G + + N +G + P + + L PL P+ + + A P
Sbjct: 961 ERFHQVPSG-----IILQNKAGGAPAAPQTSTS-----LGPLTSPAASVLVSGQAPSGTP 1010
Query: 2238 QLPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSSRPEGSQGGELSRCSSMS 2297
P P AA GL PA S+ +L ++ SS P G L S +S
Sbjct: 1011 TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSG--LQYESKLS 1068
Query: 2298 SLSR 2301
L +
Sbjct: 1069 GLKK 1072
Score = 51.6 bits (122), Expect = 9e-06
Identities = 69/241 (28%), Positives = 89/241 (36%), Gaps = 23/241 (9%)
Query: 45 TCPLQPVTDPFAFSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQ 104
T LQ VT P S A+ +TP G ++P G A + P P +
Sbjct: 580 TTVLQGVTLPP--SAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVST---- 633
Query: 105 GPCEPLPGPLTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPG 164
PLP L QP+A P + +APP + + G +S PE L P P
Sbjct: 634 ----PLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSP-GLASSPEKIVLGQPPSATP- 687
Query: 165 VDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQG---- 220
T +PLS + PH V PA+ P Q P PV
Sbjct: 688 TAILTQDSLQMFLPQERSQQPLSAEGPHLSV--PASVIVSAPPPAQDPAPATPVAKGAGL 745
Query: 221 GPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQGP-GHEQHSPL---VAPPAALP 276
GPQ SP P +P+ P P +PS+ HQ P G H P PP+ P
Sbjct: 746 GPQAPDSQASPAPAPQIPAAAPLKGPGPS-SSPSLPHQAPLGDSPHLPSPHPTRPPSRPP 804
Query: 277 S 277
S
Sbjct: 805 S 805
Score = 49.7 bits (117), Expect = 3e-05
Identities = 119/528 (22%), Positives = 177/528 (33%), Gaps = 85/528 (16%)
Query: 644 QCRPAAALPDASP--GNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVY 701
Q +PA A P A+ + PP + L P P A P+ TV
Sbjct: 569 QSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAAT------GEAAPVLTVQ 622
Query: 702 PAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPP 761
PAP+ P+ T P+ + P Q+ P AAP +P P + P
Sbjct: 623 PAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQ--------AAAPPQATTPQPSPGLASSP 674
Query: 762 EEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTE 821
E+ + GQ P SA P I ++L+ M + Q S LS P +
Sbjct: 675 EKIVLGQ----PPSATPT----AILTQDSLQ----MFLPQERSQQPLSAEGPHLSVPASV 722
Query: 822 SLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSGE 881
+ PP P A P+ L +Q+ A PA + G S
Sbjct: 723 IVSAPP-----PAQDPAPATPVAKGAGLGPQAPDSQA-SPAPAPQIPAAAPLKGPGPSSS 776
Query: 882 NTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPES 941
+ P L P + P S VS P+ +PP P P P +
Sbjct: 777 PSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQS--VSRPPS----EPPLHPCPPPQAPPT 830
Query: 942 QKDR---KAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTL 998
+ +P A++PA + PP P + H + + +
Sbjct: 831 LPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPS--STSSAV 888
Query: 999 SRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQ 1058
+ + E + P+ SD Q + P +S P L
Sbjct: 889 ASSSETSSRLPAPTPSD-FQLQFPPSQGPHKSPTPPPTL--------------------- 926
Query: 1059 QELVPPQQQASPPQLPKAMFSELSNPESLPAQGQA--QNSAQSPASLVLVDAGQQLPPRP 1116
LVP + A+PP P F ++ P Q +A + Q P+ ++L + P P
Sbjct: 927 -HLVP--EPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983
Query: 1117 PQSSSV--------SLVSSG---SGQAAVPSEQPWPQPVPALAPGPPP 1153
S+S+ S++ SG SG PS P P P A G PP
Sbjct: 984 QTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAP--APAPMAATGLPP 1029
Score = 47.8 bits (112), Expect = 1e-04
Identities = 79/282 (28%), Positives = 102/282 (36%), Gaps = 41/282 (14%)
Query: 1831 KSILTQPHLYSPVLISQLVQMASQLRLFDPQLKEKP----EEESLAAPTWLVHLQQVERQ 1886
K +L QP +P I L Q L++F PQ + + E L+ P ++ Q
Sbjct: 676 KIVLGQPPSATPTAI--LTQ--DSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ 731
Query: 1887 -------IKEGAGVWHQ---DGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVP 1936
+ +GAG+ Q A P P P++ L PG S +L PL P
Sbjct: 732 DPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAA--PLKGPGPSSSPSLPHQAPLGDSP 789
Query: 1937 -APSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGF 1995
PSP + P PS P + P P+ P+ P P P P PG LG
Sbjct: 790 HLPSPHPTRP-----PSRPPSRPQSVSRPPSEPPLHPCPPPQAP-PTLPGIFVIQNQLGV 843
Query: 1996 LEPSGPGLP--PGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANL 2053
P+ P PG PP R Q P P P P S + S +
Sbjct: 844 PPPASNPAPTAPG-PPQPPLRPQSQPPEGPLPP-APHLPPSSTSSAVASSSETSSRLPAP 901
Query: 2054 TPS---RTVPDSEAPPGWDRADSGPTQPP-LSLSPAPETKRP 2091
TPS P S+ P PT PP L L P P P
Sbjct: 902 TPSDFQLQFPPSQGP------HKSPTPPPTLHLVPEPAAPPP 937
Score = 47.0 bits (110), Expect = 2e-04
Identities = 120/490 (24%), Positives = 155/490 (31%), Gaps = 121/490 (24%)
Query: 1898 GALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVR--LLPSAPQ 1955
GA P Q PG LS+P ++ + N ++ P+ +H P LLP AP
Sbjct: 433 GAAPPQPPGA------------LSKPMSVHLLNQGSSIVIPA-QHMLPGQNQFLLPGAPA 479
Query: 1956 T-LPDGPLASPARV-------------------PMFPVPLPPGPLEPGPGCVTPGPALGF 1995
LP A PA V P+ GPL GP A
Sbjct: 480 VQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSA 539
Query: 1996 LEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTP 2055
S + G P L + L P Q AP G + + + + L P
Sbjct: 540 HILSAAPIQVGQPALFQMPVSLAAGSLPTQS---QPAPAGPAATTVLQG------VTLPP 590
Query: 2056 SRTV----PDSEAPPGWDRADSGPTQPPLSLSPAPE------TKRPGQAAKKETKEPKKG 2105
S PD P A +G P L++ PAP+ T P + + ++P
Sbjct: 591 SAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQP--- 647
Query: 2106 ESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMP-KTV 2164
P +A P P+ P P S P K V
Sbjct: 648 --------PQAPTPQAAAP---------------------PQATTPQPSPGLASSPEKIV 678
Query: 2165 QAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALA------PADFVAPL 2218
PP+ P A + S + + R L+ G S PA PA AP
Sbjct: 679 LGQPPS--ATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPA 736
Query: 2219 APLPIPSNLFVPTPDAEEPQLPDGTGREGPA----AARGLANPEPAPEPKVLSSAASLPG 2274
P+ + L PQ PD PA AA L P P+ P + A
Sbjct: 737 TPVAKGAGL--------GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDS 788
Query: 2275 SELPSSRPEGSQGGELSRCSSMSSLSREVSQH---FNQAPGDLPA-------AGGPPSGA 2324
LPS P SR S+S E H QAP LP G PP
Sbjct: 789 PHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP--- 845
Query: 2325 MPFYNPAQLA 2334
P NPA A
Sbjct: 846 -PASNPAPTA 854
Score = 44.7 bits (104), Expect = 0.001
Identities = 151/644 (23%), Positives = 218/644 (33%), Gaps = 133/644 (20%)
Query: 593 TPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALP 652
TP PKP G+ P K + + KPF A + +
Sbjct: 349 TPIQPKPAGVL---------PPKLYQLTPKPFAPAGATLTIQ------------------ 381
Query: 653 DASPGNLEQPP---DNMETLCAPQVCPLPLNSTTEAVHMLPHA-GAPPLDTVYPAPEKRP 708
PG L Q P N+ + A + + S A + + PP T AP + P
Sbjct: 382 -GEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPP 440
Query: 709 SARTQGPVKC----ESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEA 764
A ++ P+ + + + AQ LP G N L P APA+ + PQ P
Sbjct: 441 GALSK-PMSVHLLNQGSSIVIPAQHMLP--GQNQFLLPGAPAVQL---PQQLSALPAN-- 492
Query: 765 MSGQQSRNPSSAAPVQSRGG------IGASENLENPPKMGEEEALQSQASSGYASLLSSP 818
+ GQ AA GG I ++NL P +G A S A S A +LS+
Sbjct: 493 VGGQ-----ILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHS--AHILSAA 545
Query: 819 PTE----SLQNPPVLIA--------QPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGD 866
P + +L PV +A QP + A + V+L S + + LV
Sbjct: 546 PIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLV-- 603
Query: 867 RPAVSSWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNF--------PQGSGASEMVS 918
+PA + A G + T +S LP + Q PQ + + +
Sbjct: 604 QPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATT 663
Query: 919 NQPAN---------LLVQPPSQPVPENLVPES-------QKDRKAGSALPGFANSPAGST 962
QP+ +L QPPS L +S ++ ++ SA + PA S
Sbjct: 664 PQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPA-SV 722
Query: 963 SVVLVPPAH--GTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQ 1020
V PPA P A D+ + P+ PS S SL Q
Sbjct: 723 IVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQ 782
Query: 1021 QSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSE 1080
+ P P P + +P E PPQ +PP LP +
Sbjct: 783 APLGDSPHLPSPH-PTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQ---APPTLPGIFVIQ 838
Query: 1081 ----LSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRP---PQSSSVSLVSSGSGQAA 1133
+ P S PA A Q P LPP P P S+S ++ SS +
Sbjct: 839 NQLGVPPPASNPAP-TAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSR 897
Query: 1134 VPS-----------------EQPWPQPV------PALAPGPPPQ 1154
+P+ + P P P PA P PPP+
Sbjct: 898 LPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPR 941
Score = 38.5 bits (88), Expect = 0.079
Identities = 198/885 (22%), Positives = 290/885 (32%), Gaps = 161/885 (18%)
Query: 2 QPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVA----PTTCPLQPVTDPFAF 57
Q P G AGP AG +V A+ P + + PT Q + P
Sbjct: 130 QLPTLQPADGGAGPTGAGGAAAV--AAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDV 187
Query: 58 SRQALQSTP------LGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEP-- 109
+AL P LG+ + P LQG P G PG T Q +P
Sbjct: 188 VNKALSVQPFLQPVGLGNVTLQPIPGLQG-LPNG---SPGGATAATLGLAPIQVVGQPVM 243
Query: 110 -LPGPLTQPRAHASPFSGALTPSAPPG-PEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDP 167
L P +Q A P SG L +A P P SA V P V + +
Sbjct: 244 ALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLV-----IQKNLSAAVA 298
Query: 168 ETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPA--ASPSLPQPGLQMPGQWGPVQGGPQPS 225
T +G G P + V P +SP +P P + +
Sbjct: 299 TTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVIL-------------- 344
Query: 226 GQHRSPCPEGPVPSGVPCATSVPHFPTP------SILHQG-PGHEQHSPLVAPPAALPSD 278
HR+P P P P+GV P P ++ QG PG P +
Sbjct: 345 --HRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAA 402
Query: 279 GRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLA 338
G+ + + SG + + F+Q P A P Q PG + +P S V+ L
Sbjct: 403 GKAGQNVVLSG--FPAPALQANVFKQPPATTTGAAPP---QPPGALS--KPMS--VHLLN 453
Query: 339 RGDSPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQA 398
+G S H L P + GA A+ + + LS+ A + GQ
Sbjct: 454 QGSSIVIPAQHML---------PGQNQFLLPGAPAV-------QLPQQLSALPANVGGQI 497
Query: 399 DFDDFCSSPGLGRPPAPTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYEN 458
A H G + +L + AG + + + SG+ +
Sbjct: 498 ------------LAAAAPHTGGQLIANPIL--TNQNLAGPL---SLGPVLAPHSGAHSAH 540
Query: 459 VENLEFVQ-NQEVLPSEPLNLDPSSPSDQFRYGP--------LPGPAVPRHGAVCHTGAP 509
+ + +Q Q L P++L S Q + P L G +P AV P
Sbjct: 541 ILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLP-PSAVAMLNTP 599
Query: 510 DATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSS 569
D + P + + + + + A P V T + + +P+ + +
Sbjct: 600 DGLVQPATPAAATGEAAPVLTVQPAPQAPP--AVSTPLPLGLQQPQAQQPPQ-----APT 652
Query: 570 PVGGETDETTVSQNYRGSVSQP-----STPSPPKPTGIFQTSANSSFEPVKSHLVGVKPF 624
P + T Q G S P P PT I + F P + +
Sbjct: 653 PQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSA- 711
Query: 625 EADRANVVGEVRETCVRQKQCRPAAALPDASPGNL-EQPPDNMETLC-APQV-CPLPL-- 679
E +V V + Q PA A P A L Q PD+ + APQ+ PL
Sbjct: 712 EGPHLSVPASVIVSAPPPAQ-DPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKG 770
Query: 680 ---NSTTEAVHMLPHAGAPPLDTVYPA-PEKRPSARTQGPVKCESPATTLWAQSELPDFG 735
+S+ H P +P L + +P P RP +R Q
Sbjct: 771 PGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQ---------------------- 808
Query: 736 GNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGG------IGASE 789
+V P+ P L+ C PQ P P + Q P ++ P + G S+
Sbjct: 809 -SVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQ 867
Query: 790 NLENP----PKMGEEEALQSQASSGYASLLSSPPTES---LQNPP 827
E P P + + ASS S PT S LQ PP
Sbjct: 868 PPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPP 912
Score = 37.7 bits (86), Expect = 0.13
Identities = 53/230 (23%), Positives = 78/230 (33%), Gaps = 40/230 (17%)
Query: 2145 EPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQR 2204
EP PPPP M TV PPA P + R + +V P
Sbjct: 1344 EPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGA--- 1400
Query: 2205 SEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPK 2264
P PA +P P+P+ + +A + + E R L P P P
Sbjct: 1401 --PEGTPAGRARGGSPAPLPAKV----DEATSGLIRELAAVEDELYQRMLKGPPPEPAAS 1454
Query: 2265 VLSSAA----SLPGSELPSSRPEGSQGGELSRCSSMSSLSRE--VSQH----------FN 2308
PG LP ++ S+ ++ + S S ++ +++H
Sbjct: 1455 AAQGTGDPDWEAPG--LPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQ 1512
Query: 2309 QAPGDLP-------AAGGPPSGAMPFYNPAQLAQACATSGSSRLGRIGQR 2351
QAPG P A+ G P+ P + P A SS G +G R
Sbjct: 1513 QAPGRTPAPSYPHAASAGTPASPPPLHRPE------AYPPSSHNGGLGAR 1556
Score = 35.8 bits (81), Expect = 0.51
Identities = 91/402 (22%), Positives = 135/402 (33%), Gaps = 97/402 (24%)
Query: 868 PAVSSWALGGDSGENTSLSGIPTSSVLS---------------------LSLPSSVAQSN 906
P ++ G +G+N LSG P ++ + LS P SV N
Sbjct: 394 PQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLN 453
Query: 907 FPQGSG----ASEMVSNQPANLLVQPPSQPVPENL--VPESQKDRKAGSALPGFAN---- 956
QGS A M+ Q LL P+ +P+ L +P + + +A P
Sbjct: 454 --QGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIA 511
Query: 957 SPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDS 1016
+P + + P + G ++ + A HS+H LS P+ V P+
Sbjct: 512 NPILTNQNLAGPLSLGPVLAPHSGA-HSAH----------ILSAA---PIQVGQPALFQM 557
Query: 1017 LASQQSVASHPRQS--GPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLP 1074
S + S P QS P P Q VT L + ++ P P
Sbjct: 558 PVSL-AAGSLPTQSQPAPAGPAATTVLQGVT--------LPPSAVAMLNTPDGLVQPATP 608
Query: 1075 KAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAV 1134
A E + ++ QA + +P L L Q PP+ P + QAA
Sbjct: 609 AAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAP-----------TPQAAA 657
Query: 1135 PSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSL 1194
P + PQP P LA P + L PP ++ QD +
Sbjct: 658 PPQATTPQPSPGLASSP-------------------EKIVLGQPPSATPTAILTQDSLQM 698
Query: 1195 YEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQ 1236
+ P+ R +Q E S AS PPP Q
Sbjct: 699 FLPQER---------SQQPLSAEGPHLSVPASVIVSAPPPAQ 731
Score = 32.3 bits (72), Expect = 5.6
Identities = 41/164 (25%), Positives = 61/164 (37%), Gaps = 24/164 (14%)
Query: 2 QPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQA 61
QPPP + AG SV WA + ++++++ A A S A
Sbjct: 1237 QPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSA-------------ASSLDA 1283
Query: 62 LQSTPLGSSSKSSPPVLQGPAPAGFS----QHPGLL-VPHTHARDSSQGPCEPLPGPLTQ 116
+ P+ S ++ + + G Q GL V H A D +P P P T
Sbjct: 1284 DEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVH---QPPPPPATL 1340
Query: 117 PRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPH 160
A P P PP +MN + + P + PE + L PH
Sbjct: 1341 KVAEPPPRP---PPPPPPTGQMNGTVDHPPPAAPERKPLGTAPH 1381
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 58.2 bits (139), Expect = 1e-07
Identities = 92/378 (24%), Positives = 121/378 (32%), Gaps = 64/378 (16%)
Query: 68 GSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLP-------GPLTQPRAH 120
G S P V GPAP P + S G C P+P GP P
Sbjct: 106 GPPSPRRPLVPAGPAPPAAKLRP--------PPEGSAGSCAPVPAAAAVAAGPEPAPAGP 157
Query: 121 ASPFS-GALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNM 179
A P AL A PGP GP P P P PG +T +G N
Sbjct: 158 AKPAGPAALAARAGPGP--------GPGPGPGPGPGPGKPAG-PGA-AQTLNGSAALLNS 207
Query: 180 PGLDRP-LSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQHRSPCPEGPVP 238
P +S N + P P+ P +Q P P G P P P P
Sbjct: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTP----PFVGAAAPPAPAAPSPPAAPAP 263
Query: 239 SGVPCATSVPHFPTPSILHQGPGHEQHSPLVAP-----------------PAALPSDGRD 281
+ P A P P P+ L + PGH P AP PA P+ G
Sbjct: 264 AA-PAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP 322
Query: 282 EVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGD 341
Q G A + ++P+ V A P + AS ++ P +G
Sbjct: 323 AGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGA 382
Query: 342 SPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFD 401
P P G +G GA+GA+ T + +A
Sbjct: 383 LPSPAAVPPPAPGTPTG-----LPKGAAGAVTQSLSRTPTATTSGI---------RATLT 428
Query: 402 DFCSSPGLGRPPA-PTHV 418
+P L +PP PT++
Sbjct: 429 PTVLAPRLPQPPQNPTNI 446
Score = 45.1 bits (105), Expect = 8e-04
Identities = 117/484 (24%), Positives = 150/484 (30%), Gaps = 112/484 (23%)
Query: 1844 LISQLVQMASQLRLFDPQLKEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQ 1903
L SQL A+ P+ PE + AA H+ GAG P
Sbjct: 29 LESQLAASAAHHHHLAPRT---PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGA 85
Query: 1904 CPGTPSSEMEQLDRPGLSQPGALGIANPLL----AVPA----PSPEHSSPSVRLLPSAPQ 1955
P P + + G +PG PL+ A PA P PE S+ S +P+A
Sbjct: 86 APEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAA 145
Query: 1956 TL------------PDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGL 2003
P GP A AR PGP PGPG PGP G +P+GPG
Sbjct: 146 VAAGPEPAPAGPAKPAGPAALAARA-------GPGP-GPGPG---PGPGPGPGKPAGPGA 194
Query: 2004 PP---GVPPLQERRHLLQEA----RSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPS 2056
G L H A + ++P P + + F G A P+
Sbjct: 195 AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPG-TVIQTPPFVG--AAAPPA 251
Query: 2057 RTVPDSEAPPGWDRADSGPTQPPLSLSPAPET--KRPGQAAKKETKEPKKGESWFFRWLP 2114
P A P + P PP PAP T + PG A T P
Sbjct: 252 PAAPSPPAAPAPAAPAAAPPPPP----PAPATLARPPGHPAGPPTAAP------------ 295
Query: 2115 GKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAP---PAL 2171
PPP + AAP PA
Sbjct: 296 ------------------------------------AVPPPAAAQNGGSAGAAPAPAPAA 319
Query: 2172 PGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEP-------ALAPADFVAPLAPLPIP 2224
GP G AA A V +P ++ P A PA A + P
Sbjct: 320 GGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTM 379
Query: 2225 SNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVLSSA--ASLPGSELPSSRP 2282
+P+P A P P GT P A G + P +S A+L + L P
Sbjct: 380 QGA-LPSPAAVPPPAP-GTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLP 437
Query: 2283 EGSQ 2286
+ Q
Sbjct: 438 QPPQ 441
Score = 43.5 bits (101), Expect = 0.002
Identities = 103/427 (24%), Positives = 130/427 (30%), Gaps = 102/427 (23%)
Query: 1927 GIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPAR--VPMFPVPLPPGPLEPGP 1984
G A P P +PE P+ R P GP SP R VP P P P L P P
Sbjct: 74 GPAAPAEGAPGAAPE-PPPAGRARPGGGGPQRPGP-PSPRRPLVPAGPAP-PAAKLRPPP 130
Query: 1985 ----GCVTPGPALGFLE------PSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPV 2034
G P PA + P+GP P G L R P PG P P
Sbjct: 131 EGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAG---PGPGPGPGPGPGPGP- 186
Query: 2035 GNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQA 2094
G + + +G A L A P ++GP +L P P+ PG
Sbjct: 187 GKPAGPGAAQTLNGSAALLNSHHA-----AAPAVSLVNNGPA----ALLPLPKPAAPGTV 237
Query: 2095 AKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPP 2154
+ +V P AP
Sbjct: 238 IQTPP----------------------------------------FVGAAAPPAPA-APS 256
Query: 2155 PPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADF 2214
PP P AAPP PP AP + R G +P+G + PA+ P
Sbjct: 257 PPAAPAPAAPAAAPPP---PPPAPATL--ARPPG---------HPAGPPTAAPAVPP--- 299
Query: 2215 VAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANP-EPAPEPKVLSSAASLP 2273
P A S P P +G+ GP AA P A PK + AA
Sbjct: 300 --PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPA 357
Query: 2274 GSELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPFYNPAQL 2333
L +S P + + + +L PAA PP+ P P
Sbjct: 358 AQTLAASGPASTAASMVIGPTMQGALPS-------------PAAVPPPAPGTPTGLPKGA 404
Query: 2334 AQACATS 2340
A A S
Sbjct: 405 AGAVTQS 411
Score = 38.9 bits (89), Expect = 0.060
Identities = 92/404 (22%), Positives = 134/404 (33%), Gaps = 74/404 (18%)
Query: 1918 PGLSQPGALGIANPLLAVPAPSPEH--SSPSVRLLPSAPQTLPDGPL-ASPARV----PM 1970
PG +P G A L A H ++P+V L+ + P L P A+P V P
Sbjct: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243
Query: 1971 FPVPLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERRHLLQEARSPD-PGIVP 2029
PP P P P P PA P P PP L AR P P P
Sbjct: 244 VGAAAPPAPAAPSPPAA-PAPAAPAAAPPPP--PPAPATL---------ARPPGHPAGPP 291
Query: 2030 QEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETK 2089
AP VP A A + P P + PA +
Sbjct: 292 TAAPA------------------------VPPPAAAQNGGSAGAAPAPAPAAGGPAGVSG 327
Query: 2090 RPGQAAKKETKEP-KKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEE 2148
+PG A P K ES K+ +A P + + + +
Sbjct: 328 QPGPGAAAAAPAPGVKAES-------PKRVVQAAPPAAQTLAASGPASTAASMVIG---P 377
Query: 2149 EKKAPPPPPTSMPKTVQAAPPALP-GPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEP 2207
+ P P ++P P LP G GA SR T + L P+
Sbjct: 378 TMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPT------- 430
Query: 2208 ALAPADFVAPLAPLPI------PSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAP 2261
LAP P P I P + V + + + +P + A A AP
Sbjct: 431 VLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAP 490
Query: 2262 EPKVLSSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQ 2305
P +SA P ++ + + G+ ++R + +++ ++VSQ
Sbjct: 491 RPATPTSA---PPVQISTVQAPGTP--IIARQVTPTTIIKQVSQ 529
Score = 35.4 bits (80), Expect = 0.67
Identities = 55/227 (24%), Positives = 79/227 (34%), Gaps = 47/227 (20%)
Query: 1030 SGPGAPNLDRFYQQVTKDAQGQPGLE-------RAQQELVPPQQQASP-PQLPKAMFSEL 1081
+GP AP A+G PG RA+ PQ+ P P+ P
Sbjct: 73 AGPAAP------------AEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPA 120
Query: 1082 SNPESL--PAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQP 1139
L P +G A + A PA+ + + P P + + + +++ +G P P
Sbjct: 121 PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGP 180
Query: 1140 WPQPVPALAPGP-PPQDLAAYYYYRPLYDAYQPQYS-----------LPYPPEPGAASLY 1187
P P P GP Q L + A P S LP P PG
Sbjct: 181 GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTV--- 237
Query: 1188 YQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPP 1234
+ P P+ GAA+ A P P P+ A ++ PPP
Sbjct: 238 ------IQTP---PFVGAAAPPAPAAPSP-PAAPAPAAPAAAPPPPP 274
Score = 35.4 bits (80), Expect = 0.67
Identities = 119/558 (21%), Positives = 175/558 (31%), Gaps = 108/558 (19%)
Query: 586 GSVSQPSTPSPPKP---TGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQ 642
G +P PSP +P G +A P + P A A G
Sbjct: 100 GGPQRPGPPSPRRPLVPAGPAPPAAKLR-PPPEGSAGSCAPVPAAAAVAAGPEPAPAGPA 158
Query: 643 KQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLP--HAGAPPLDTV 700
K PAA A PG P P + + +L HA AP + V
Sbjct: 159 KPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLV 218
Query: 701 YPAPEKRPSARTQGPVKCESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQP 760
P+A P K +P T + + P F G AP APA P PP
Sbjct: 219 ----NNGPAALLPLP-KPAAPGTVI----QTPPFVGAA--APPAPAA-----PSPPAAPA 262
Query: 761 PEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPT 820
P + P+ A + G + PP + A +G ++ + P
Sbjct: 263 PAAPAAAPPPPPPAPATLARPPG------HPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA 316
Query: 821 ESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVSSWALGGDSG 880
+ P + QP A P P V + +S
Sbjct: 317 PAAGGPAGVSGQPGPGAAAAAPA------------------------PGVKA-----ESP 347
Query: 881 ENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPE 940
+ + P + L+ S P+S A AS ++ L P + P P P
Sbjct: 348 KRVVQAAPPAAQTLAASGPASTA---------ASMVIGPTMQGALPSPAAVPPPAPGTPT 398
Query: 941 SQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSR 1000
AG+ + +P +TS + TL P L L +
Sbjct: 399 GLPKGAAGAVTQSLSRTPTATTSGI-----RATLTPT---------------VLAPRLPQ 438
Query: 1001 TLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQE 1060
+NP N+ N + +S ++G + Q+ A QP A +
Sbjct: 439 PPQNPTNIQNFQLPPGMVLVRS------ENGQLLMIPQQALAQMQAQAHAQPQTTMAPRP 492
Query: 1061 LVP---PQQQASPPQLP-KAMFSELSNPESLPAQ-GQAQNSAQSPASLVLVDAGQQLPPR 1115
P P Q S Q P + + P ++ Q QAQ + Q A+L Q+ P
Sbjct: 493 ATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATL------QRSPGV 546
Query: 1116 PPQSSSVSLVSSGSGQAA 1133
PQ LV G+ Q A
Sbjct: 547 QPQ-----LVLGGAAQTA 559
Score = 35.4 bits (80), Expect = 0.67
Identities = 36/141 (25%), Positives = 49/141 (34%), Gaps = 21/141 (14%)
Query: 3 PPPQTVPSGMAGPP--PAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 60
PPP P+ +A PP PAG P + P + +A AP P
Sbjct: 271 PPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAP------------- 317
Query: 61 ALQSTPLGSSSKSSP-PVLQGPAPAGFSQHPGLLV---PHTHARDSSQGPCEPLPGPLTQ 116
P G S + P PAP ++ P +V P ++ GP +
Sbjct: 318 -AAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG 376
Query: 117 PRAH-ASPFSGALTPSAPPGP 136
P A P A+ P AP P
Sbjct: 377 PTMQGALPSPAAVPPPAPGTP 397
Score = 34.3 bits (77), Expect = 1.5
Identities = 73/309 (23%), Positives = 95/309 (30%), Gaps = 64/309 (20%)
Query: 198 PAASPSLPQPGLQMPGQWGP------------VQGGPQPSGQHRSPCPEG------PVPS 239
P A+P P G PG GP V GP P P PEG PVP+
Sbjct: 83 PGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPA 142
Query: 240 G---------VPCATSVPHFPTPSILHQGPG-HEQHSPLVAPPAALPSDGRDEVSHLQSG 289
P + P P GPG P P P+ G L
Sbjct: 143 AAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPA-GPGAAQTLNGS 201
Query: 290 SHLAN------------NSDPES-----------TFRQNPRIVNHWA--SPELRQNPGVK 324
+ L N N+ P + T Q P V A +P P
Sbjct: 202 AALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAP 261
Query: 325 NEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENE 384
PA+A P + HP G + P A + G+ G
Sbjct: 262 APAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGS------AGAAPAP 315
Query: 385 ENLSSEKAGLSGQADFDDFCSSPGLG-RPPAPTHV--GAGSLCQAL-LPGPSNEAAGDVW 440
+ AG+SGQ ++P G + +P V A Q L GP++ AA V
Sbjct: 316 APAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVI 375
Query: 441 GDTASTGVP 449
G T +P
Sbjct: 376 GPTMQGALP 384
Score = 32.3 bits (72), Expect = 5.6
Identities = 46/182 (25%), Positives = 65/182 (35%), Gaps = 39/182 (21%)
Query: 2186 AAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVP---------TPDAEE 2236
AAG +V +P+G + PA APA+ AP P P+ P P
Sbjct: 54 AAGALGNHVVSGSPAGAAGAGPA-APAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRR 112
Query: 2237 PQLPDGT------------GREG-----PAAARGLANPEPAPE-------PKVLSSAASL 2272
P +P G G G PAAA A PEPAP P L++ A
Sbjct: 113 PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAG- 171
Query: 2273 PG---SELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPFYN 2329
PG P P + +++ + ++ H AP + P+ +P
Sbjct: 172 PGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPA-VSLVNNGPAALLPLPK 230
Query: 2330 PA 2331
PA
Sbjct: 231 PA 232
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 58.2 bits (139), Expect = 1e-07
Identities = 98/434 (22%), Positives = 148/434 (34%), Gaps = 60/434 (13%)
Query: 1863 KEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGLSQ 1922
KE+ + E + P QQ + I + G G P Q GTP S Q SQ
Sbjct: 198 KEQGKPEGIIKPPLQ---QQPPKPIPKQQG----PGRDPLQQDGTPKSISSQQPEKIKSQ 250
Query: 1923 PGALG--IANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPL 1980
P G I P P +H+ ++ S PQT + + P P P P
Sbjct: 251 PPGTGKPIQGP---TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ 307
Query: 1981 EPGPGCVTPGPALGFLEPS-GPGLPPGVP-----PLQERRHLLQEARSPDPGIVPQEAPV 2034
+P PG P G + GP PP P PL ++ ++ P P P+
Sbjct: 308 QPTPG-KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366
Query: 2035 GNSLSELSEENFDGKFANLTPSRTVPDSEA---PPGWDRADS---GPTQPPLSL--SPAP 2086
G + + + PS P +A PPG + + GP +PP +P P
Sbjct: 367 GPAKPPAQQTGSE------KPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 2087 ETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEP 2146
++PG + P K PG KT P + Q +
Sbjct: 421 LAQQPG------LQSPAKA--------PGPTKTPVQQPGP-------GKIPAQQAGPGKT 459
Query: 2147 EEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSE 2206
++ P PP+ +P + PP PGP P +A ++ P Q
Sbjct: 460 SAQQTGPTKPPSQLPGPAKP-PPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGP 516
Query: 2207 PALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVL 2266
+P + P P + P A++P + ++ + +P P V
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSA---KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 2267 SSAASLPGSELPSS 2280
SA P LP +
Sbjct: 574 PSAKQPPSQGLPKT 587
Score = 57.8 bits (138), Expect = 1e-07
Identities = 122/532 (22%), Positives = 184/532 (34%), Gaps = 120/532 (22%)
Query: 1901 PQQCPGT--PSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLP 1958
P Q PG+ P S+ +P QPG A P P + S PSA Q P
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGP---AKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546
Query: 1959 DGPLASPARVPMFPV----PLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERR 2014
P A + P+ PL P + P +P GLP + PL
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK-----------QPPSQGLPKTICPLCNTT 595
Query: 2015 HLLQEAR---------------------SPDPGIVP----------QEAPVGNSLSEL-S 2042
LL +P+P + + +G L+ + S
Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
Query: 2043 EENFDGKFANLTPSRTVPDSEAPPGWD--RADSGPTQPPLSLSPAPETKRPGQAAKKET- 2099
K A +T + V S P + D+ P Q LS APE K+P K+ T
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ---DLSKAPEPKKPPPLVKQPTL 712
Query: 2100 --------KEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLN------- 2144
K+P + +S + P K E +P +++K+ V D+K Q +
Sbjct: 713 HGSPSAKAKQPPEADS-LSKPAPPK---EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVS 768
Query: 2145 ---------------EPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGT 2189
+ + E+K PP T K Q+ PP G V+ + +A
Sbjct: 769 SSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT-----GEKVSPFDSKAIPR 823
Query: 2190 RARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGR---E 2246
A +++ G D V P PDA+ +P G+
Sbjct: 824 PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK--PMPKGSPTPPGP 881
Query: 2247 GPAAARGLANPEPAPEPKVLSSAASLP-GS--ELPSSRPEGSQ---GGEL--------SR 2292
P A + + P+ +P+P+ S SL GS + P S+P Q G+L S+
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 2293 CSSMSSLSREVSQHFNQAPG----DLPAAGGPPSGAMPFYNPAQLAQACATS 2340
S++ S + + H PG PA PP+ P + Q A A S
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKS 993
Score = 56.6 bits (135), Expect = 3e-07
Identities = 71/299 (23%), Positives = 107/299 (35%), Gaps = 50/299 (16%)
Query: 1900 LPQQCPGTPSSEM--EQLDRPGLSQPGAL--GIANPLLAVPAPSPEHSSPSVRLLPSAPQ 1955
+ Q PG P ++ + +PG ++P A G+ PL P P P A
Sbjct: 306 IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ- 364
Query: 1956 TLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFL--EPSGPGLPP----GVP- 2008
P GP PA+ P +PGP + P +G + GP PP G P
Sbjct: 365 --PLGPAKPPAQQTGSE---KPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK 419
Query: 2009 PLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAP--- 2065
PL ++ L A++P P P + P + +++ GK + T P S+ P
Sbjct: 420 PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP--AQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 2066 -------------PGWDRADSGPTQPPLSLSPAPETKRPGQAAKKE---TKEPKKGESWF 2109
P + P+Q P S P P+ P + + ++ TK P +
Sbjct: 478 KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ---- 533
Query: 2110 FRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPP----PPPTSMPKTV 2164
PG K A P S K +P + P PP +PKT+
Sbjct: 534 ----PGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Score = 49.7 bits (117), Expect = 3e-05
Identities = 90/341 (26%), Positives = 122/341 (35%), Gaps = 59/341 (17%)
Query: 2 QPPPQTVPSGMA-GPPPA---GNPRSVFWASSPYRRRANNNAAVAPTTCPLQ-PVTDPFA 56
Q PP+ +P G P G P+S+ + P + ++ P P Q P TD
Sbjct: 213 QQPPKPIPKQQGPGRDPLQQDGTPKSIS-SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAK 271
Query: 57 FSRQALQSTPL--------GSSSK------SSPPVLQGPAPAGFSQHPGLLVPHTHARDS 102
Q S P G S K S PP+ Q +Q PG H + S
Sbjct: 272 LPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPG------HEK-S 324
Query: 103 SQGPCEP--LPGPLTQPRAHASPFSGALTPSA-PPGPEMNRSAEVGPSSEPEVQTLPYLP 159
GP +P P LT+P A G + P PPG + +GP+ P QT P
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQP---GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 160 H----------YIPGV--DPETSHG-GHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQ 206
PGV P G P G +PL++Q G+ +PA +P +
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ---PGLQSPAKAPGPTK 438
Query: 207 PGLQMPG-------QWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQG 259
+Q PG Q GP + Q +G + P + P P+ P P P P
Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPP-SQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 260 PGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPES 300
Q PP P G + S Q GS + P S
Sbjct: 498 KPPSQQPGSTKPPPQQP--GPAKPSPQQPGSTKPPSQQPGS 536
Score = 46.6 bits (109), Expect = 3e-04
Identities = 80/339 (23%), Positives = 112/339 (33%), Gaps = 56/339 (16%)
Query: 2002 GLPPGV--PPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTV 2059
G P G+ PPLQ++ P I Q+ P + L + DG +++ +
Sbjct: 201 GKPEGIIKPPLQQQ---------PPKPIPKQQGPGRDPLQQ------DGTPKSISSQQPE 245
Query: 2060 PDSEAPPGWDRADSGPTQPP------LSL---SPAPETKRP----GQAAKKETKEPKKGE 2106
PPG + GPTQ P L L + P+TK+ G++ K P K
Sbjct: 246 KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP 305
Query: 2107 SWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQA 2166
P K A P + + Q L +P ++ PP P T +
Sbjct: 306 I----QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK- 360
Query: 2167 APPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSN 2226
PPA P P P A+ PS Q ALA V P P
Sbjct: 361 -PPAQPLGPAKP-----------PAQQTGSEKPSSEQPGPKALAQPPGVGK-TPAQQPGP 407
Query: 2227 LFVPTPDAEEPQ-LPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSSRPEGS 2285
PT P+ L G + PA A P P P +P + +
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKA-----PGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462
Query: 2286 QGGELSRCSSMSSLSREVSQHFNQA--PGDLPAAGGPPS 2322
Q G S + ++ Q A P P + PPS
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS 501
Score = 44.7 bits (104), Expect = 0.001
Identities = 190/910 (20%), Positives = 299/910 (32%), Gaps = 182/910 (20%)
Query: 448 VPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTG 507
+ D+ SQ E + + VQ ++ P + P Q P+P P + G
Sbjct: 179 ISDSEASQEETTKKQKVVQKEQGKPEGIIK----PPLQQQPPKPIPKQQGPGRDPLQQDG 234
Query: 508 APDATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQID 567
P S+SS + + G+ +P IQ P+ + + ++
Sbjct: 235 TPK---------SISSQQPEKIKSQPPGTGKP-------IQGPTQTPQTDHAKLPLQRDA 278
Query: 568 SSPVGGETDETTVSQNYRGSVSQPSTPSPPKP---------------------TGIFQTS 606
S P +T + RG +PS PSP KP G +
Sbjct: 279 SRP------QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPP 332
Query: 607 ANSS--FEPVKSHLVGVKP------FEADRANVVGEVRETCVRQKQCRPAAALPDASPGN 658
A S +P+ VKP A +G + + +P++ P P
Sbjct: 333 AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP--GPKA 390
Query: 659 LEQPPDNMETLCAPQVCPLPLNSTTEAVHM-LPHAGAPPLDT--VYPAPEKRPSARTQGP 715
L QPP +T P P P T+ V P A P L + P P K P + GP
Sbjct: 391 LAQPPGVGKT---PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP-VQQPGP 446
Query: 716 VKCES----PATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQ-- 769
K + P T AQ P + L PA P +PP QP QQ
Sbjct: 447 GKIPAQQAGPGKTS-AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505
Query: 770 SRNP----------------SSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYAS 813
S P S+ P Q G S +P K +++ + + +G
Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565
Query: 814 LLSSPP-TESLQNPP---------VLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREAL 863
L P + S + PP L + ++ + NF N+ + Q+ +L
Sbjct: 566 PLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANF-----NTCTECQTTVCSL 620
Query: 864 VGDRP-----AVSSW---------ALGGD-----SGENTSLSGIPTSSVLSLSLPSSVAQ 904
G P V W ALGGD S L P ++ ++S S Q
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ 680
Query: 905 SNFPQGSGASEM-------------------VSNQPANLLVQPP-----SQPVP--ENLV 938
P+ A + + P+ QPP S+P P E V
Sbjct: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740
Query: 939 PESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPD--GNKANHSSHQEDTYGALDF 996
P Q P +T LV + T PD +K + ++ T
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTD--LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD 798
Query: 997 TLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLER 1056
+ + P S DS A + + S PG P+ + Q+ Q + ++
Sbjct: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG-PSSESKGQKQVDPVQKKEEPKK 857
Query: 1057 AQQELVP-------PQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAG 1109
AQ ++ P P+ +PP + P+ P + Q Q+ S + DA
Sbjct: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP-KPQEQSRRFSLNLGSITDAP 916
Query: 1110 QQLPPRPPQSSSVSLVSSG----SGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPL 1165
+ P P ++ + L G S + + S P P PG P + A +P
Sbjct: 917 KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA--PSQPP 974
Query: 1166 YDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPER-PSSR 1224
P+ + PP P + P A A P+ E+ P+ +
Sbjct: 975 TSQGPPKSTGQAPPAPAKSI---------------PVKKETKAPAAEKLEPKAEQAPTVK 1019
Query: 1225 ASHSSERPPP 1234
+ + ++PPP
Sbjct: 1020 RTETEKKPPP 1029
Score = 42.7 bits (99), Expect = 0.004
Identities = 84/344 (24%), Positives = 117/344 (34%), Gaps = 82/344 (23%)
Query: 921 PANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNK 980
P+ +Q P+ P P +K + + P P+G T + P GT+ P
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA---QPSGLTKPLAQQP--GTVKPPVQP 355
Query: 981 ANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHP-RQSGPGAPNLDR 1039
+ G +T + P +LA V P +Q GP P
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK-ALAQPPGVGKTPAQQPGPAKPPT-- 412
Query: 1040 FYQQV--TKDAQGQPGLERAQQELVP---PQQQASPPQLPKAMFSELSNPESLPAQGQAQ 1094
QQV K QPGL+ + P P QQ P ++P ++ + P AQ Q
Sbjct: 413 --QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP----AQQAGPGKTSAQ---Q 463
Query: 1095 NSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQ 1154
P S + G PP P Q G A PS+QP + PPPQ
Sbjct: 464 TGPTKPPSQL---PGPAKPP-PQQPGPAKPPPQQPGSAKPPSQQPG-------STKPPPQ 512
Query: 1155 DLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYR 1214
QP + P P +PG S P +P G+A AQ
Sbjct: 513 ---------------QPGPAKPSPQQPG----------STKPPSQQP--GSAKPSAQQ-- 543
Query: 1215 YPEPERPSSRAS------------------HSSERPPPRQGYPE 1240
P P +PS++ S S + PP QG P+
Sbjct: 544 -PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Score = 42.0 bits (97), Expect = 0.007
Identities = 85/375 (22%), Positives = 131/375 (34%), Gaps = 61/375 (16%)
Query: 2000 GPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTV 2059
G GLP G+ A SP +P A + LS+LSEE A ++ ++ +
Sbjct: 9 GEGLPEGLAAAAAAGGGASGAGSPSHTAIP--AGMEADLSQLSEEERRQIAAVMSRAQGL 66
Query: 2060 PDSEAPPGWDRADS-------GPTQPPLSLSPAPETKRPGQ--AAKKETKEPKKGESWFF 2110
P PP + S + PP P+ RP Q +K T + + E
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSE---- 122
Query: 2111 RWLPGKKKTEAYLPDDKNKSIVWDEKKNQW-----------------VNLNEPEE---EK 2150
+ LPG+ + L + K+++ + +E K+ VN P + +
Sbjct: 123 QKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDS 182
Query: 2151 KAPPPPPTSMPKTV---QAAPPALPGPP---GAPVNMYSRRAAGTRARYVDVLNPSGTQR 2204
+A T K V Q P + PP P + ++ G D L GT +
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGR-----DPLQQDGTPK 237
Query: 2205 SEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAA-----ARGLANPEP 2259
S + P + P TP + +LP P RG +
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297
Query: 2260 APEPKVLSSAASLPGSELPSSRP--EGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAA 2317
P P PG P+ +P E SQ G + S L++ ++Q PG +
Sbjct: 298 LPSPSKPPIQQPTPGKP-PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ----PGTVKPP 352
Query: 2318 GGPPSGAMPFYNPAQ 2332
PP P PAQ
Sbjct: 353 VQPPGTTKP---PAQ 364
Score = 35.4 bits (80), Expect = 0.67
Identities = 157/793 (19%), Positives = 256/793 (32%), Gaps = 149/793 (18%)
Query: 407 PGLGRPPA-PTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFV 465
PG +PPA P Q PS+E G + P G
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP-----KALAQPPGVGKTPAQQPGPAKP 410
Query: 466 QNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAV-PRHGAV-CHTGAPDATLHTVHPDSVSS 523
Q+V +PL P S GP P P G + P T S
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT-------SAQQ 463
Query: 524 SYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQN 583
+ ++ +L G A+P Q KP + GS + P + T
Sbjct: 464 TGPTKPPSQLPGPAKPPPQ-----QPGPAKPPPQQPGS------AKPPSQQPGSTKPPPQ 512
Query: 584 YRGSVSQPSTPSPPKPTGIFQTSAN-SSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQ 642
G P+ PSP +P S S +P KP V +
Sbjct: 513 QPG----PAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG---- 564
Query: 643 KQCRPAAALPDASPGNLEQPPDN--METLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTV 700
K +P P A +QPP +T+C PL +TTE +L H
Sbjct: 565 KPLQPPTVSPSA-----KQPPSQGLPKTIC-------PLCNTTE---LLLHV-------- 601
Query: 701 YPAPEKRPSARTQGPVKCESPATTLWAQSELPDF-----------------GGNVLLAPA 743
PEK A +C++ +L + P GG++ P+
Sbjct: 602 ---PEK---ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
Query: 744 APALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEAL 803
+P + P + + QQ+ AAP Q + + + PP + ++ L
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD---LSKAPEPKKPPPLVKQPTL 712
Query: 804 QSQASSGYASLLSSPPTESLQNP---------------PVLIAQPDHSYNLAQPINFSVS 848
S A P +SL P PV +P + +P VS
Sbjct: 713 HGSPS---AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP-KMVKPTTDLVS 768
Query: 849 LSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLP------SSV 902
S++ K P + S + + E T+ S+ S S P S
Sbjct: 769 SSSATTK------------PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 903 AQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGST 962
P+ + S+++S+ + + Q P E +K + S P P GS
Sbjct: 817 DSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP 876
Query: 963 SVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQS 1022
+ P G VP ++ Q + N ++ + S Q++
Sbjct: 877 TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL----------NLGSITDAPKSQPTTPQET 926
Query: 1023 VASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELS 1082
V + G GA + ++ GQPG P +Q +P Q P + S
Sbjct: 927 VTG--KLFGFGASIFSQASNLIS--TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS 982
Query: 1083 NPESLPAQGQA---QNSAQSPASLVLVDAGQQLP--------PRPPQSSSVSLVSSGSGQ 1131
++ PA ++ + ++PA+ L +Q P +PP +++ +
Sbjct: 983 TGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQK 1042
Query: 1132 AAVPSE-QPWPQP 1143
A +P++ + P+P
Sbjct: 1043 AVLPTKLEKSPKP 1055
Score = 35.4 bits (80), Expect = 0.67
Identities = 72/289 (24%), Positives = 104/289 (35%), Gaps = 55/289 (19%)
Query: 1897 DGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQT 1956
D A P Q ++ D + +P + + +++ P PS E S ++ P +
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPAS---DSKIISHPGPSSE-SKGQKQVDPVQKKE 853
Query: 1957 LPDGPLASPARVPMFPVP----LPPG-PLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQ 2011
P A+ M P P +P G P PGP P G P+ P P Q
Sbjct: 854 EP-----KKAQTKMSPKPDAKPMPKGSPTPPGPR-----PTAGQTVPTPQQSPK--PQEQ 901
Query: 2012 ERRHLLQ-----EARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPP 2066
RR L +A P PQE G + T + P S++ P
Sbjct: 902 SRRFSLNLGSITDAPKSQP-TTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 2067 GWDRADS-GPTQPPLSLSP------APETKRPGQAAKKETK-------EPKKGESWFFRW 2112
G + P+QPP S P AP KKETK EPK ++
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQA----- 1015
Query: 2113 LPGKKKTEAYL---PDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPT 2158
P K+TE P +KS+ + +K P + +K+P P T
Sbjct: 1016 -PTVKRTETEKKPPPIKDSKSLTAEPQKAVL-----PTKLEKSPKPEST 1058
Score = 32.3 bits (72), Expect = 5.6
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Query: 2146 PEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRS 2205
P+ + ++ PPTS Q + PAL P AP + + + Y ++P TQ +
Sbjct: 3870 PQTQTESQLVPPTSPYTQYQYSSPAL--PTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPT 3927
Query: 2206 EPALAPADFVAPLAPLPIP 2224
A+A F + P P P
Sbjct: 3928 FQAVATMSFTPQVQPTPTP 3946
Score = 31.6 bits (70), Expect = 9.6
Identities = 40/161 (24%), Positives = 59/161 (36%), Gaps = 19/161 (11%)
Query: 1936 PAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGF 1995
PA SPSV LP+ P+ + P P P PP P P P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQP--PPPPPPPPPPPPP----------- 2418
Query: 1996 LEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTP 2055
P P PP PP + +L + + V P+ ++++ L E +N P
Sbjct: 2419 --PPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTL--ETTAVLRSNGLP 2474
Query: 2056 SRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAK 2096
+ + PP + S P+ L + PE +P A K
Sbjct: 2475 VTRICTTAPPPVPPKPSSIPS--GLVFTHRPEPSKPPIAPK 2513
Score = 31.6 bits (70), Expect = 9.6
Identities = 33/140 (23%), Positives = 48/140 (34%), Gaps = 15/140 (10%)
Query: 2146 PEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRAR----YVDVLNPSG 2201
P PPPPP P PP P P P + + T A V L +
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTA 2466
Query: 2202 TQRSEPALAPADFVAPLAPLPIPSN--------LFVPTPDAEEPQL-PDGTGREGPAAAR 2252
RS P + AP P+P +F P+ +P + P + P +
Sbjct: 2467 VLRSNG--LPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQ 2524
Query: 2253 GLANPEPAPEPKVLSSAASL 2272
+ P P L+S+ +L
Sbjct: 2525 KPTDIHPKPTGLSLTSSMTL 2544
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 58.2 bits (139), Expect = 1e-07
Identities = 98/434 (22%), Positives = 148/434 (34%), Gaps = 60/434 (13%)
Query: 1863 KEKPEEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQCPGTPSSEMEQLDRPGLSQ 1922
KE+ + E + P QQ + I + G G P Q GTP S Q SQ
Sbjct: 198 KEQGKPEGIIKPPLQ---QQPPKPIPKQQG----PGRDPLQQDGTPKSISSQQPEKIKSQ 250
Query: 1923 PGALG--IANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPL 1980
P G I P P +H+ ++ S PQT + + P P P P
Sbjct: 251 PPGTGKPIQGP---TQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ 307
Query: 1981 EPGPGCVTPGPALGFLEPS-GPGLPPGVP-----PLQERRHLLQEARSPDPGIVPQEAPV 2034
+P PG P G + GP PP P PL ++ ++ P P P+
Sbjct: 308 QPTPG-KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366
Query: 2035 GNSLSELSEENFDGKFANLTPSRTVPDSEA---PPGWDRADS---GPTQPPLSL--SPAP 2086
G + + + PS P +A PPG + + GP +PP +P P
Sbjct: 367 GPAKPPAQQTGSE------KPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 2087 ETKRPGQAAKKETKEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEP 2146
++PG + P K PG KT P + Q +
Sbjct: 421 LAQQPG------LQSPAKA--------PGPTKTPVQQPGP-------GKIPAQQAGPGKT 459
Query: 2147 EEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSE 2206
++ P PP+ +P + PP PGP P +A ++ P Q
Sbjct: 460 SAQQTGPTKPPSQLPGPAKP-PPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGP 516
Query: 2207 PALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKVL 2266
+P + P P + P A++P + ++ + +P P V
Sbjct: 517 AKPSPQQPGSTKPPSQQPGSA---KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 2267 SSAASLPGSELPSS 2280
SA P LP +
Sbjct: 574 PSAKQPPSQGLPKT 587
Score = 57.8 bits (138), Expect = 1e-07
Identities = 122/532 (22%), Positives = 184/532 (34%), Gaps = 120/532 (22%)
Query: 1901 PQQCPGT--PSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLP 1958
P Q PG+ P S+ +P QPG A P P + S PSA Q P
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGP---AKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546
Query: 1959 DGPLASPARVPMFPV----PLPPGPLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQERR 2014
P A + P+ PL P + P +P GLP + PL
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAK-----------QPPSQGLPKTICPLCNTT 595
Query: 2015 HLLQEAR---------------------SPDPGIVP----------QEAPVGNSLSEL-S 2042
LL +P+P + + +G L+ + S
Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
Query: 2043 EENFDGKFANLTPSRTVPDSEAPPGWD--RADSGPTQPPLSLSPAPETKRPGQAAKKET- 2099
K A +T + V S P + D+ P Q LS APE K+P K+ T
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ---DLSKAPEPKKPPPLVKQPTL 712
Query: 2100 --------KEPKKGESWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLN------- 2144
K+P + +S + P K E +P +++K+ V D+K Q +
Sbjct: 713 HGSPSAKAKQPPEADS-LSKPAPPK---EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVS 768
Query: 2145 ---------------EPEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGT 2189
+ + E+K PP T K Q+ PP G V+ + +A
Sbjct: 769 SSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT-----GEKVSPFDSKAIPR 823
Query: 2190 RARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGR---E 2246
A +++ G D V P PDA+ +P G+
Sbjct: 824 PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK--PMPKGSPTPPGP 881
Query: 2247 GPAAARGLANPEPAPEPKVLSSAASLP-GS--ELPSSRPEGSQ---GGEL--------SR 2292
P A + + P+ +P+P+ S SL GS + P S+P Q G+L S+
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 2293 CSSMSSLSREVSQHFNQAPG----DLPAAGGPPSGAMPFYNPAQLAQACATS 2340
S++ S + + H PG PA PP+ P + Q A A S
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKS 993
Score = 56.6 bits (135), Expect = 3e-07
Identities = 71/299 (23%), Positives = 107/299 (35%), Gaps = 50/299 (16%)
Query: 1900 LPQQCPGTPSSEM--EQLDRPGLSQPGAL--GIANPLLAVPAPSPEHSSPSVRLLPSAPQ 1955
+ Q PG P ++ + +PG ++P A G+ PL P P P A
Sbjct: 306 IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ- 364
Query: 1956 TLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGFL--EPSGPGLPP----GVP- 2008
P GP PA+ P +PGP + P +G + GP PP G P
Sbjct: 365 --PLGPAKPPAQQTGSE---KPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK 419
Query: 2009 PLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAP--- 2065
PL ++ L A++P P P + P + +++ GK + T P S+ P
Sbjct: 420 PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP--AQQAGPGKTSAQQTGPTKPPSQLPGPA 477
Query: 2066 -------------PGWDRADSGPTQPPLSLSPAPETKRPGQAAKKE---TKEPKKGESWF 2109
P + P+Q P S P P+ P + + ++ TK P +
Sbjct: 478 KPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ---- 533
Query: 2110 FRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPP----PPPTSMPKTV 2164
PG K A P S K +P + P PP +PKT+
Sbjct: 534 ----PGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Score = 49.7 bits (117), Expect = 3e-05
Identities = 90/341 (26%), Positives = 122/341 (35%), Gaps = 59/341 (17%)
Query: 2 QPPPQTVPSGMA-GPPPA---GNPRSVFWASSPYRRRANNNAAVAPTTCPLQ-PVTDPFA 56
Q PP+ +P G P G P+S+ + P + ++ P P Q P TD
Sbjct: 213 QQPPKPIPKQQGPGRDPLQQDGTPKSIS-SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAK 271
Query: 57 FSRQALQSTPL--------GSSSK------SSPPVLQGPAPAGFSQHPGLLVPHTHARDS 102
Q S P G S K S PP+ Q +Q PG H + S
Sbjct: 272 LPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPG------HEK-S 324
Query: 103 SQGPCEP--LPGPLTQPRAHASPFSGALTPSA-PPGPEMNRSAEVGPSSEPEVQTLPYLP 159
GP +P P LT+P A G + P PPG + +GP+ P QT P
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQP---GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 160 H----------YIPGV--DPETSHG-GHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQ 206
PGV P G P G +PL++Q G+ +PA +P +
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ---PGLQSPAKAPGPTK 438
Query: 207 PGLQMPG-------QWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSVPHFPTPSILHQG 259
+Q PG Q GP + Q +G + P + P P+ P P P P
Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPP-SQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 260 PGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPES 300
Q PP P G + S Q GS + P S
Sbjct: 498 KPPSQQPGSTKPPPQQP--GPAKPSPQQPGSTKPPSQQPGS 536
Score = 46.6 bits (109), Expect = 3e-04
Identities = 80/339 (23%), Positives = 112/339 (33%), Gaps = 56/339 (16%)
Query: 2002 GLPPGV--PPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTV 2059
G P G+ PPLQ++ P I Q+ P + L + DG +++ +
Sbjct: 201 GKPEGIIKPPLQQQ---------PPKPIPKQQGPGRDPLQQ------DGTPKSISSQQPE 245
Query: 2060 PDSEAPPGWDRADSGPTQPP------LSL---SPAPETKRP----GQAAKKETKEPKKGE 2106
PPG + GPTQ P L L + P+TK+ G++ K P K
Sbjct: 246 KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP 305
Query: 2107 SWFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQA 2166
P K A P + + Q L +P ++ PP P T +
Sbjct: 306 I----QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK- 360
Query: 2167 APPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRSEPALAPADFVAPLAPLPIPSN 2226
PPA P P P A+ PS Q ALA V P P
Sbjct: 361 -PPAQPLGPAKP-----------PAQQTGSEKPSSEQPGPKALAQPPGVGK-TPAQQPGP 407
Query: 2227 LFVPTPDAEEPQ-LPDGTGREGPAAARGLANPEPAPEPKVLSSAASLPGSELPSSRPEGS 2285
PT P+ L G + PA A P P P +P + +
Sbjct: 408 AKPPTQQVGTPKPLAQQPGLQSPAKA-----PGPTKTPVQQPGPGKIPAQQAGPGKTSAQ 462
Query: 2286 QGGELSRCSSMSSLSREVSQHFNQA--PGDLPAAGGPPS 2322
Q G S + ++ Q A P P + PPS
Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS 501
Score = 44.7 bits (104), Expect = 0.001
Identities = 190/910 (20%), Positives = 299/910 (32%), Gaps = 182/910 (20%)
Query: 448 VPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTG 507
+ D+ SQ E + + VQ ++ P + P Q P+P P + G
Sbjct: 179 ISDSEASQEETTKKQKVVQKEQGKPEGIIK----PPLQQQPPKPIPKQQGPGRDPLQQDG 234
Query: 508 APDATLHTVHPDSVSSSYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQID 567
P S+SS + + G+ +P IQ P+ + + ++
Sbjct: 235 TPK---------SISSQQPEKIKSQPPGTGKP-------IQGPTQTPQTDHAKLPLQRDA 278
Query: 568 SSPVGGETDETTVSQNYRGSVSQPSTPSPPKP---------------------TGIFQTS 606
S P +T + RG +PS PSP KP G +
Sbjct: 279 SRP------QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPP 332
Query: 607 ANSS--FEPVKSHLVGVKP------FEADRANVVGEVRETCVRQKQCRPAAALPDASPGN 658
A S +P+ VKP A +G + + +P++ P P
Sbjct: 333 AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP--GPKA 390
Query: 659 LEQPPDNMETLCAPQVCPLPLNSTTEAVHM-LPHAGAPPLDT--VYPAPEKRPSARTQGP 715
L QPP +T P P P T+ V P A P L + P P K P + GP
Sbjct: 391 LAQPPGVGKT---PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP-VQQPGP 446
Query: 716 VKCES----PATTLWAQSELPDFGGNVLLAPAAPALYVCAKPQPPVVQPPEEAMSGQQ-- 769
K + P T AQ P + L PA P +PP QP QQ
Sbjct: 447 GKIPAQQAGPGKTS-AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505
Query: 770 SRNP----------------SSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYAS 813
S P S+ P Q G S +P K +++ + + +G
Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565
Query: 814 LLSSPP-TESLQNPP---------VLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREAL 863
L P + S + PP L + ++ + NF N+ + Q+ +L
Sbjct: 566 PLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANF-----NTCTECQTTVCSL 620
Query: 864 VGDRP-----AVSSW---------ALGGD-----SGENTSLSGIPTSSVLSLSLPSSVAQ 904
G P V W ALGGD S L P ++ ++S S Q
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ 680
Query: 905 SNFPQGSGASEM-------------------VSNQPANLLVQPP-----SQPVP--ENLV 938
P+ A + + P+ QPP S+P P E V
Sbjct: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740
Query: 939 PESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPD--GNKANHSSHQEDTYGALDF 996
P Q P +T LV + T PD +K + ++ T
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTD--LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD 798
Query: 997 TLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLER 1056
+ + P S DS A + + S PG P+ + Q+ Q + ++
Sbjct: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG-PSSESKGQKQVDPVQKKEEPKK 857
Query: 1057 AQQELVP-------PQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQSPASLVLVDAG 1109
AQ ++ P P+ +PP + P+ P + Q Q+ S + DA
Sbjct: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP-KPQEQSRRFSLNLGSITDAP 916
Query: 1110 QQLPPRPPQSSSVSLVSSG----SGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPL 1165
+ P P ++ + L G S + + S P P PG P + A +P
Sbjct: 917 KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA--PSQPP 974
Query: 1166 YDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPER-PSSR 1224
P+ + PP P + P A A P+ E+ P+ +
Sbjct: 975 TSQGPPKSTGQAPPAPAKSI---------------PVKKETKAPAAEKLEPKAEQAPTVK 1019
Query: 1225 ASHSSERPPP 1234
+ + ++PPP
Sbjct: 1020 RTETEKKPPP 1029
Score = 42.7 bits (99), Expect = 0.004
Identities = 84/344 (24%), Positives = 117/344 (34%), Gaps = 82/344 (23%)
Query: 921 PANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNK 980
P+ +Q P+ P P +K + + P P+G T + P GT+ P
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA---QPSGLTKPLAQQP--GTVKPPVQP 355
Query: 981 ANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHP-RQSGPGAPNLDR 1039
+ G +T + P +LA V P +Q GP P
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK-ALAQPPGVGKTPAQQPGPAKPPT-- 412
Query: 1040 FYQQV--TKDAQGQPGLERAQQELVP---PQQQASPPQLPKAMFSELSNPESLPAQGQAQ 1094
QQV K QPGL+ + P P QQ P ++P ++ + P AQ Q
Sbjct: 413 --QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP----AQQAGPGKTSAQ---Q 463
Query: 1095 NSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQ 1154
P S + G PP P Q G A PS+QP + PPPQ
Sbjct: 464 TGPTKPPSQL---PGPAKPP-PQQPGPAKPPPQQPGSAKPPSQQPG-------STKPPPQ 512
Query: 1155 DLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYR 1214
QP + P P +PG S P +P G+A AQ
Sbjct: 513 ---------------QPGPAKPSPQQPG----------STKPPSQQP--GSAKPSAQQ-- 543
Query: 1215 YPEPERPSSRAS------------------HSSERPPPRQGYPE 1240
P P +PS++ S S + PP QG P+
Sbjct: 544 -PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Score = 42.0 bits (97), Expect = 0.007
Identities = 85/375 (22%), Positives = 131/375 (34%), Gaps = 61/375 (16%)
Query: 2000 GPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTV 2059
G GLP G+ A SP +P A + LS+LSEE A ++ ++ +
Sbjct: 9 GEGLPEGLAAAAAAGGGASGAGSPSHTAIP--AGMEADLSQLSEEERRQIAAVMSRAQGL 66
Query: 2060 PDSEAPPGWDRADS-------GPTQPPLSLSPAPETKRPGQ--AAKKETKEPKKGESWFF 2110
P PP + S + PP P+ RP Q +K T + + E
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSE---- 122
Query: 2111 RWLPGKKKTEAYLPDDKNKSIVWDEKKNQW-----------------VNLNEPEE---EK 2150
+ LPG+ + L + K+++ + +E K+ VN P + +
Sbjct: 123 QKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDS 182
Query: 2151 KAPPPPPTSMPKTV---QAAPPALPGPP---GAPVNMYSRRAAGTRARYVDVLNPSGTQR 2204
+A T K V Q P + PP P + ++ G D L GT +
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGR-----DPLQQDGTPK 237
Query: 2205 SEPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAA-----ARGLANPEP 2259
S + P + P TP + +LP P RG +
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297
Query: 2260 APEPKVLSSAASLPGSELPSSRP--EGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAA 2317
P P PG P+ +P E SQ G + S L++ ++Q PG +
Sbjct: 298 LPSPSKPPIQQPTPGKP-PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ----PGTVKPP 352
Query: 2318 GGPPSGAMPFYNPAQ 2332
PP P PAQ
Sbjct: 353 VQPPGTTKP---PAQ 364
Score = 35.4 bits (80), Expect = 0.67
Identities = 157/793 (19%), Positives = 256/793 (32%), Gaps = 149/793 (18%)
Query: 407 PGLGRPPA-PTHVGAGSLCQALLPGPSNEAAGDVWGDTASTGVPDASGSQYENVENLEFV 465
PG +PPA P Q PS+E G + P G
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP-----KALAQPPGVGKTPAQQPGPAKP 410
Query: 466 QNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAV-PRHGAV-CHTGAPDATLHTVHPDSVSS 523
Q+V +PL P S GP P P G + P T S
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT-------SAQQ 463
Query: 524 SYSSRSHGRLSGSARPQELVGTFIQQEVGKPEDEASGSFFKQIDSSPVGGETDETTVSQN 583
+ ++ +L G A+P Q KP + GS + P + T
Sbjct: 464 TGPTKPPSQLPGPAKPPPQ-----QPGPAKPPPQQPGS------AKPPSQQPGSTKPPPQ 512
Query: 584 YRGSVSQPSTPSPPKPTGIFQTSAN-SSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQ 642
G P+ PSP +P S S +P KP V +
Sbjct: 513 QPG----PAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG---- 564
Query: 643 KQCRPAAALPDASPGNLEQPPDN--METLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTV 700
K +P P A +QPP +T+C PL +TTE +L H
Sbjct: 565 KPLQPPTVSPSA-----KQPPSQGLPKTIC-------PLCNTTE---LLLHV-------- 601
Query: 701 YPAPEKRPSARTQGPVKCESPATTLWAQSELPDF-----------------GGNVLLAPA 743
PEK A +C++ +L + P GG++ P+
Sbjct: 602 ---PEK---ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
Query: 744 APALYVCAKPQPPVVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEAL 803
+P + P + + QQ+ AAP Q + + + PP + ++ L
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD---LSKAPEPKKPPPLVKQPTL 712
Query: 804 QSQASSGYASLLSSPPTESLQNP---------------PVLIAQPDHSYNLAQPINFSVS 848
S A P +SL P PV +P + +P VS
Sbjct: 713 HGSPS---AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP-KMVKPTTDLVS 768
Query: 849 LSNSHEKNQSWREALVGDRPAVSSWALGGDSGENTSLSGIPTSSVLSLSLP------SSV 902
S++ K P + S + + E T+ S+ S S P S
Sbjct: 769 SSSATTK------------PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 903 AQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGST 962
P+ + S+++S+ + + Q P E +K + S P P GS
Sbjct: 817 DSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP 876
Query: 963 SVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQS 1022
+ P G VP ++ Q + N ++ + S Q++
Sbjct: 877 TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL----------NLGSITDAPKSQPTTPQET 926
Query: 1023 VASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFSELS 1082
V + G GA + ++ GQPG P +Q +P Q P + S
Sbjct: 927 VTG--KLFGFGASIFSQASNLIS--TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS 982
Query: 1083 NPESLPAQGQA---QNSAQSPASLVLVDAGQQLP--------PRPPQSSSVSLVSSGSGQ 1131
++ PA ++ + ++PA+ L +Q P +PP +++ +
Sbjct: 983 TGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQK 1042
Query: 1132 AAVPSE-QPWPQP 1143
A +P++ + P+P
Sbjct: 1043 AVLPTKLEKSPKP 1055
Score = 35.4 bits (80), Expect = 0.67
Identities = 72/289 (24%), Positives = 104/289 (35%), Gaps = 55/289 (19%)
Query: 1897 DGALPQQCPGTPSSEMEQLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQT 1956
D A P Q ++ D + +P + + +++ P PS E S ++ P +
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPAS---DSKIISHPGPSSE-SKGQKQVDPVQKKE 853
Query: 1957 LPDGPLASPARVPMFPVP----LPPG-PLEPGPGCVTPGPALGFLEPSGPGLPPGVPPLQ 2011
P A+ M P P +P G P PGP P G P+ P P Q
Sbjct: 854 EP-----KKAQTKMSPKPDAKPMPKGSPTPPGPR-----PTAGQTVPTPQQSPK--PQEQ 901
Query: 2012 ERRHLLQ-----EARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTPSRTVPDSEAPP 2066
RR L +A P PQE G + T + P S++ P
Sbjct: 902 SRRFSLNLGSITDAPKSQP-TTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 2067 GWDRADS-GPTQPPLSLSP------APETKRPGQAAKKETK-------EPKKGESWFFRW 2112
G + P+QPP S P AP KKETK EPK ++
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQA----- 1015
Query: 2113 LPGKKKTEAYL---PDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPT 2158
P K+TE P +KS+ + +K P + +K+P P T
Sbjct: 1016 -PTVKRTETEKKPPPIKDSKSLTAEPQKAVL-----PTKLEKSPKPEST 1058
Score = 32.3 bits (72), Expect = 5.6
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Query: 2146 PEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRS 2205
P+ + ++ PPTS Q + PAL P AP + + + Y ++P TQ +
Sbjct: 3870 PQTQTESQLVPPTSPYTQYQYSSPAL--PTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPT 3927
Query: 2206 EPALAPADFVAPLAPLPIP 2224
A+A F + P P P
Sbjct: 3928 FQAVATMSFTPQVQPTPTP 3946
Score = 31.6 bits (70), Expect = 9.6
Identities = 40/161 (24%), Positives = 59/161 (36%), Gaps = 19/161 (11%)
Query: 1936 PAPSPEHSSPSVRLLPSAPQTLPDGPLASPARVPMFPVPLPPGPLEPGPGCVTPGPALGF 1995
PA SPSV LP+ P+ + P P P PP P P P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQP--PPPPPPPPPPPPP----------- 2418
Query: 1996 LEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQEAPVGNSLSELSEENFDGKFANLTP 2055
P P PP PP + +L + + V P+ ++++ L E +N P
Sbjct: 2419 --PPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTL--ETTAVLRSNGLP 2474
Query: 2056 SRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAK 2096
+ + PP + S P+ L + PE +P A K
Sbjct: 2475 VTRICTTAPPPVPPKPSSIPS--GLVFTHRPEPSKPPIAPK 2513
Score = 31.6 bits (70), Expect = 9.6
Identities = 33/140 (23%), Positives = 48/140 (34%), Gaps = 15/140 (10%)
Query: 2146 PEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRAR----YVDVLNPSG 2201
P PPPPP P PP P P P + + T A V L +
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTA 2466
Query: 2202 TQRSEPALAPADFVAPLAPLPIPSN--------LFVPTPDAEEPQL-PDGTGREGPAAAR 2252
RS P + AP P+P +F P+ +P + P + P +
Sbjct: 2467 VLRSNG--LPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQ 2524
Query: 2253 GLANPEPAPEPKVLSSAASL 2272
+ P P L+S+ +L
Sbjct: 2525 KPTDIHPKPTGLSLTSSMTL 2544
>gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming
sequence-like 1 [Homo sapiens]
Length = 491
Score = 57.4 bits (137), Expect = 2e-07
Identities = 72/269 (26%), Positives = 98/269 (36%), Gaps = 65/269 (24%)
Query: 1 MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQ 60
++ PP + MA PPP + F S+ R ++N T P+Q ++
Sbjct: 260 IRAPPAEL--SMAPPPPRSVSQETFRIST----RKHSNLI----TVPIQDDSN------- 302
Query: 61 ALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGL----LVPHTHARDSSQ---GPCEPLPGP 113
S ++ PP PAPA HP +V H H Q P P P P
Sbjct: 303 --------SGAREPPP----PAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPP 350
Query: 114 LTQPRAHASPFSGA---LTPSAPPGPEMNRSAEVGPSSEPEV-QTLPYLPHYIPGVDPET 169
++ P H +G + APP P + + P + Q PY+ H PG P
Sbjct: 351 ISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPG-PPPP 409
Query: 170 SHGGHP-------HGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGP 222
HGG P H N L + Q SP QPG PG W P GP
Sbjct: 410 QHGGPPVTAPPPHHYNPNSLPQFTEDQG--------TLSPPFTQPGGMSPGIW-PAPRGP 460
Query: 223 QPSGQHRSPCPEGPVPSGVPCATSVPHFP 251
P + + P + P+P PH P
Sbjct: 461 PPPPRLQGPPSQTPLPG--------PHHP 481
Score = 50.4 bits (119), Expect = 2e-05
Identities = 49/189 (25%), Positives = 64/189 (33%), Gaps = 38/189 (20%)
Query: 1936 PAPSPEHSSPSVR----------LLPSAPQTLPDGPLASPARVPMFPVP----------- 1974
PAP+P H P + ++P P P P PM P
Sbjct: 311 PAPAPAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYS 370
Query: 1975 -LPPGPLEPGPGCVTPGPA--LGFLEPSGPGLPPGVPPLQERRHLLQEARSPDPGIVPQE 2031
PP P+ P +TP P + + P PPG PP P G P
Sbjct: 371 QAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPP-------------PQHGGPPVT 417
Query: 2032 APVGNSLSELSEENFDGKFANLTPSRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRP 2091
AP + + S F L+P T P +P W A GP PP P +T P
Sbjct: 418 APPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWP-APRGPPPPPRLQGPPSQTPLP 476
Query: 2092 GQAAKKETK 2100
G +T+
Sbjct: 477 GPHHPDQTR 485
Score = 35.4 bits (80), Expect = 0.67
Identities = 51/209 (24%), Positives = 62/209 (29%), Gaps = 47/209 (22%)
Query: 81 PAPAGFSQHPGLLVPHTHAR--------DSSQGPCEPLPGPLTQPRAHASPFSGALTPSA 132
P P SQ + H+ DS+ G EP P P P H + G S
Sbjct: 272 PPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREP-PPPAPAPAHHHPEYQGQPVVSH 330
Query: 133 PPG--PEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRPLSRQN 190
P P A P P +P+ P G PH L
Sbjct: 331 PHHIMPPQQHYAPPPPPPPPISHPMPHPPQA----------AGTPH---------LVYSQ 371
Query: 191 PHDGVVTPAASPSLPQPG---LQMPGQWGPVQGGPQPSGQHRSPCPEGPVPSGVPCATSV 247
+T A P P PG QMP P H P P P G P
Sbjct: 372 APPPPMTSAPPPITPPPGHIIAQMP-----------PYMNHPPPGPPPPQHGGPPVTAPP 420
Query: 248 PHFPTPSILHQGPGHEQHSPLVAPPAALP 276
PH P+ L P + ++PP P
Sbjct: 421 PHHYNPNSL---PQFTEDQGTLSPPFTQP 446
Score = 32.0 bits (71), Expect = 7.4
Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 27/173 (15%)
Query: 1020 QQSVASHPRQSGPGAPNLDRFYQQVTKDAQGQPGLERAQQELVPPQQQASPPQLPKAMFS 1079
Q S R+ P AP + + QGQP + + P Q A PP P
Sbjct: 298 QDDSNSGAREPPPPAPAPAHHHPEY----QGQPVVSHPHHIMPPQQHYAPPPPPP----P 349
Query: 1080 ELSNPESLPAQGQAQNSAQSPASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQ--AAVP-- 1135
+S+P P Q A LV A P PP +S+ ++ G A +P
Sbjct: 350 PISHPMPHPPQ------AAGTPHLVYSQA-----PPPPMTSAPPPITPPPGHIIAQMPPY 398
Query: 1136 SEQPWPQPVPALAPGPPPQDLAAYYY---YRPLYDAYQPQYSLPYPPEPGAAS 1185
P P P P GPP ++Y P + Q S P+ +PG S
Sbjct: 399 MNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPF-TQPGGMS 450
Score = 31.6 bits (70), Expect = 9.6
Identities = 44/176 (25%), Positives = 60/176 (34%), Gaps = 50/176 (28%)
Query: 2146 PEEEKKAPPPPPTSMPKTVQAAPPALPGPPGAPVNMYSRRAAGTRARYVDVLNPSGTQRS 2205
P ++ APPPPP P + P P G P +YS+ P T
Sbjct: 336 PPQQHYAPPPPP---PPPISHPMPHPPQAAGTPHLVYSQAPP-----------PPMTSAP 381
Query: 2206 EPALAPADFVAPLAPLPIPSNLFVPTPDAEEPQLPDGTGREGPAAARGLANPEPAPEPKV 2265
P P + +A +P N P P PQ GP P AP P
Sbjct: 382 PPITPPPGHI--IAQMPPYMN--HPPPGPPPPQ------HGGP--------PVTAPPPHH 423
Query: 2266 LSSAASLPGSELPSSRPEGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPP 2321
+ P+S P+ ++ +LS +Q +PG PA GPP
Sbjct: 424 YN----------PNSLPQFTE--------DQGTLSPPFTQPGGMSPGIWPAPRGPP 461
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 125,222,083
Number of Sequences: 37866
Number of extensions: 8307347
Number of successful extensions: 55502
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 143
Number of HSP's successfully gapped in prelim test: 1787
Number of HSP's that attempted gapping in prelim test: 31717
Number of HSP's gapped (non-prelim): 20388
length of query: 2357
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2238
effective length of database: 13,741,464
effective search space: 30753396432
effective search space used: 30753396432
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.