Guide to the Human Genome
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Search of human proteins with 12408663

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12408663 T-lymphocyte maturation-associated protein isoform
c [Homo sapiens]
         (97 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12408663 T-lymphocyte maturation-associated protein isoform c...   195   7e-51
gi|4505091 T-lymphocyte maturation-associated protein isoform a ...   160   2e-40
gi|12408661 T-lymphocyte maturation-associated protein isoform b...    96   8e-21
gi|12408665 T-lymphocyte maturation-associated protein isoform d...    91   2e-19
gi|239741714 PREDICTED: hypothetical protein XP_002342305 [Homo ...    53   5e-08
gi|13162283 mal, T-cell differentiation protein-like [Homo sapiens]    53   5e-08
gi|169164947 PREDICTED: similar to mal, T-cell differentiation p...    46   6e-06
gi|169164253 PREDICTED: similar to mal, T-cell differentiation p...    46   6e-06
gi|169163277 PREDICTED: similar to mal, T-cell differentiation p...    46   6e-06
gi|16418397 MAL2 proteolipid protein [Homo sapiens]                    43   5e-05
gi|31657096 chemokine-like factor superfamily 4 isoform 2 [Homo ...    32   0.14 
gi|30520333 chemokine-like factor superfamily 4 isoform 1 [Homo ...    32   0.14 
gi|66932929 myeloid-associated differentiation marker [Homo sapi...    29   0.71 
gi|66932927 myeloid-associated differentiation marker [Homo sapi...    29   0.71 
gi|66932925 myeloid-associated differentiation marker [Homo sapi...    29   0.71 
gi|66932923 myeloid-associated differentiation marker [Homo sapi...    29   0.71 
gi|19923903 myeloid-associated differentiation marker [Homo sapi...    29   0.71 
gi|4885121 chemokine (C-C motif) receptor 8 [Homo sapiens]             29   0.71 
gi|154759277 monocyte to macrophage differentiation-associated 2...    29   0.92 
gi|154759275 monocyte to macrophage differentiation-associated 2...    29   0.92 
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i...    27   4.6  
gi|223278370 myeloid-associated differentiation marker-like 2 [H...    26   6.0  
gi|13786129 RAB33B, member RAS oncogene family [Homo sapiens]          26   7.8  

>gi|12408663 T-lymphocyte maturation-associated protein isoform c
          [Homo sapiens]
          Length = 97

 Score =  195 bits (495), Expect = 7e-51
 Identities = 97/97 (100%), Positives = 97/97 (100%)

Query: 1  MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFDAAYHCTAALFYLSASVLEALATITMQDG 60
          MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFDAAYHCTAALFYLSASVLEALATITMQDG
Sbjct: 1  MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFDAAYHCTAALFYLSASVLEALATITMQDG 60

Query: 61 FTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS 97
          FTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
Sbjct: 61 FTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS 97


>gi|4505091 T-lymphocyte maturation-associated protein isoform a
           [Homo sapiens]
          Length = 153

 Score =  160 bits (405), Expect = 2e-40
 Identities = 95/153 (62%), Positives = 95/153 (62%), Gaps = 56/153 (36%)

Query: 1   MAPAAATGGSTLPSGFSVFTTLPDLL----FIF--------------------------- 29
           MAPAAATGGSTLPSGFSVFTTLPDLL    FIF                           
Sbjct: 1   MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV 60

Query: 30  -------------------------EFDAAYHCTAALFYLSASVLEALATITMQDGFTYR 64
                                      DAAYHCTAALFYLSASVLEALATITMQDGFTYR
Sbjct: 61  FCFVATTTLIILYIIGAHGGETSWVTLDAAYHCTAALFYLSASVLEALATITMQDGFTYR 120

Query: 65  HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS 97
           HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS
Sbjct: 121 HYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS 153


>gi|12408661 T-lymphocyte maturation-associated protein isoform b
           [Homo sapiens]
          Length = 111

 Score = 95.5 bits (236), Expect = 8e-21
 Identities = 59/111 (53%), Positives = 68/111 (61%), Gaps = 14/111 (12%)

Query: 1   MAPAAATGGSTLPSGFSVFTTLPDLLFIFEF---DAAYHCTAA-----------LFYLSA 46
           MAPAAATGGSTLPSGFSVFTTLPDLLFIFEF      +   A+           + ++S 
Sbjct: 1   MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFIFGGLVWILVASSLVPWPLVQGWVMFVSV 60

Query: 47  SVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS 97
               A  T+ +           +   +VFSYIATLLYVVHAVFSLIRWKSS
Sbjct: 61  FCFVATTTLIILYIIGAHGGETSWVTLVFSYIATLLYVVHAVFSLIRWKSS 111


>gi|12408665 T-lymphocyte maturation-associated protein isoform d
          [Homo sapiens]
          Length = 55

 Score = 90.9 bits (224), Expect = 2e-19
 Identities = 55/97 (56%), Positives = 55/97 (56%), Gaps = 42/97 (43%)

Query: 1  MAPAAATGGSTLPSGFSVFTTLPDLLFIFEFDAAYHCTAALFYLSASVLEALATITMQDG 60
          MAPAAATGGSTLPSGFSVFTTLPDLLFIFEF                             
Sbjct: 1  MAPAAATGGSTLPSGFSVFTTLPDLLFIFEF----------------------------- 31

Query: 61 FTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS 97
                       VFSYIATLLYVVHAVFSLIRWKSS
Sbjct: 32 -------------VFSYIATLLYVVHAVFSLIRWKSS 55


>gi|239741714 PREDICTED: hypothetical protein XP_002342305 [Homo
           sapiens]
          Length = 231

 Score = 53.1 bits (126), Expect = 5e-08
 Identities = 26/56 (46%), Positives = 37/56 (66%)

Query: 32  DAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHA 87
           D+ YH T  + Y+SA+VL+  ATI  +     R Y+ N AA  F++IATLLY++HA
Sbjct: 170 DSLYHGTTGILYMSAAVLQVHATIVSEKLLDPRIYYINSAASFFAFIATLLYILHA 225


>gi|13162283 mal, T-cell differentiation protein-like [Homo sapiens]
          Length = 153

 Score = 53.1 bits (126), Expect = 5e-08
 Identities = 26/56 (46%), Positives = 37/56 (66%)

Query: 32  DAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHA 87
           D+ YH T  + Y+SA+VL+  ATI  +     R Y+ N AA  F++IATLLY++HA
Sbjct: 92  DSLYHGTTGILYMSAAVLQVHATIVSEKLLDPRIYYINSAASFFAFIATLLYILHA 147


>gi|169164947 PREDICTED: similar to mal, T-cell differentiation
           protein-like [Homo sapiens]
          Length = 130

 Score = 46.2 bits (108), Expect = 6e-06
 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 5/66 (7%)

Query: 26  LFIFE----FDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATL 81
           LF FE     D+ YH T  + Y+SA+VL+    I M +    R+Y  N AA+ F+++  L
Sbjct: 60  LFGFESWRVLDSLYHGTTGILYMSAAVLQVHVMI-MSEAQDLRNYCINTAALFFAFVTML 118

Query: 82  LYVVHA 87
           LY++HA
Sbjct: 119 LYILHA 124


>gi|169164253 PREDICTED: similar to mal, T-cell differentiation
           protein-like [Homo sapiens]
          Length = 130

 Score = 46.2 bits (108), Expect = 6e-06
 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 5/66 (7%)

Query: 26  LFIFE----FDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATL 81
           LF FE     D+ YH T  + Y+SA+VL+    I M +    R+Y  N AA+ F+++  L
Sbjct: 60  LFGFESWRVLDSLYHGTTGILYMSAAVLQVHVMI-MSEAQDLRNYCINTAALFFAFVTML 118

Query: 82  LYVVHA 87
           LY++HA
Sbjct: 119 LYILHA 124


>gi|169163277 PREDICTED: similar to mal, T-cell differentiation
           protein-like [Homo sapiens]
          Length = 130

 Score = 46.2 bits (108), Expect = 6e-06
 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 5/66 (7%)

Query: 26  LFIFE----FDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATL 81
           LF FE     D+ YH T  + Y+SA+VL+    I M +    R+Y  N AA+ F+++  L
Sbjct: 60  LFGFESWRVLDSLYHGTTGILYMSAAVLQVHVMI-MSEAQDLRNYCINTAALFFAFVTML 118

Query: 82  LYVVHA 87
           LY++HA
Sbjct: 119 LYILHA 124


>gi|16418397 MAL2 proteolipid protein [Homo sapiens]
          Length = 176

 Score = 43.1 bits (100), Expect = 5e-05
 Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 10/74 (13%)

Query: 32  DAAYHCTAALFYLSASVLEALAT----------ITMQDGFTYRHYHENIAAVVFSYIATL 81
           D AYH T  +FY  A +LEA AT          IT Q   +   Y+ N+AA +F+++ T 
Sbjct: 102 DFAYHFTVFVFYFGAFLLEAAATSLHDLHCNTTITGQPLLSDNQYNINVAASIFAFMTTA 161

Query: 82  LYVVHAVFSLIRWK 95
            Y      +L RW+
Sbjct: 162 CYGCSLGLALRRWR 175


>gi|31657096 chemokine-like factor superfamily 4 isoform 2 [Homo
           sapiens]
          Length = 208

 Score = 31.6 bits (70), Expect = 0.14
 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 10/60 (16%)

Query: 38  TAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS 97
           +A LF++++ VL AL          +R   E IAAV+F ++AT  Y V+   ++ +W+ S
Sbjct: 129 SAFLFFIASIVLAAL---------NHRAGAE-IAAVIFGFLATAAYAVNTFLAVQKWRVS 178


>gi|30520333 chemokine-like factor superfamily 4 isoform 1 [Homo
           sapiens]
          Length = 234

 Score = 31.6 bits (70), Expect = 0.14
 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 10/60 (16%)

Query: 38  TAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFSLIRWKSS 97
           +A LF++++ VL AL          +R   E IAAV+F ++AT  Y V+   ++ +W+ S
Sbjct: 129 SAFLFFIASIVLAAL---------NHRAGAE-IAAVIFGFLATAAYAVNTFLAVQKWRVS 178


>gi|66932929 myeloid-associated differentiation marker [Homo
           sapiens]
          Length = 322

 Score = 29.3 bits (64), Expect = 0.71
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 31  FDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFS 90
           F   + C AALF LSAS++    T  +Q     R     IAA  FS IA + Y     ++
Sbjct: 101 FPITFACYAALFCLSASII--YPTTYVQFLSHGRSRDHAIAATFFSCIACVAYATEVAWT 158

Query: 91  LIR 93
             R
Sbjct: 159 RAR 161


>gi|66932927 myeloid-associated differentiation marker [Homo
           sapiens]
          Length = 322

 Score = 29.3 bits (64), Expect = 0.71
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 31  FDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFS 90
           F   + C AALF LSAS++    T  +Q     R     IAA  FS IA + Y     ++
Sbjct: 101 FPITFACYAALFCLSASII--YPTTYVQFLSHGRSRDHAIAATFFSCIACVAYATEVAWT 158

Query: 91  LIR 93
             R
Sbjct: 159 RAR 161


>gi|66932925 myeloid-associated differentiation marker [Homo
           sapiens]
          Length = 322

 Score = 29.3 bits (64), Expect = 0.71
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 31  FDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFS 90
           F   + C AALF LSAS++    T  +Q     R     IAA  FS IA + Y     ++
Sbjct: 101 FPITFACYAALFCLSASII--YPTTYVQFLSHGRSRDHAIAATFFSCIACVAYATEVAWT 158

Query: 91  LIR 93
             R
Sbjct: 159 RAR 161


>gi|66932923 myeloid-associated differentiation marker [Homo
           sapiens]
          Length = 322

 Score = 29.3 bits (64), Expect = 0.71
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 31  FDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFS 90
           F   + C AALF LSAS++    T  +Q     R     IAA  FS IA + Y     ++
Sbjct: 101 FPITFACYAALFCLSASII--YPTTYVQFLSHGRSRDHAIAATFFSCIACVAYATEVAWT 158

Query: 91  LIR 93
             R
Sbjct: 159 RAR 161


>gi|19923903 myeloid-associated differentiation marker [Homo
           sapiens]
          Length = 322

 Score = 29.3 bits (64), Expect = 0.71
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 2/63 (3%)

Query: 31  FDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVFS 90
           F   + C AALF LSAS++    T  +Q     R     IAA  FS IA + Y     ++
Sbjct: 101 FPITFACYAALFCLSASII--YPTTYVQFLSHGRSRDHAIAATFFSCIACVAYATEVAWT 158

Query: 91  LIR 93
             R
Sbjct: 159 RAR 161


>gi|4885121 chemokine (C-C motif) receptor 8 [Homo sapiens]
          Length = 355

 Score = 29.3 bits (64), Expect = 0.71
 Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 22  LPDLLFIFEFDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATL 81
           L DLLF+F F          +YL    +       +  GF Y  ++ ++  +    +   
Sbjct: 79  LSDLLFVFSFPFQ------TYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRY 132

Query: 82  LYVVHAVFSL 91
           L VVHAV++L
Sbjct: 133 LAVVHAVYAL 142


>gi|154759277 monocyte to macrophage differentiation-associated 2
          isoform 1 [Homo sapiens]
          Length = 270

 Score = 28.9 bits (63), Expect = 0.92
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 30 EFDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVF 89
          E++ A +C    F++  S+L +     + D        E I+A ++      L+VV  VF
Sbjct: 32 EYEHAANCATHAFWIIPSILGSSNLYFLSDDDW-----ETISAWIYGLGLCGLFVVSTVF 86

Query: 90 SLIRWKSS 97
            I WK S
Sbjct: 87 HTISWKKS 94


>gi|154759275 monocyte to macrophage differentiation-associated 2
          isoform 2 [Homo sapiens]
          Length = 246

 Score = 28.9 bits (63), Expect = 0.92
 Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 30 EFDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIATLLYVVHAVF 89
          E++ A +C    F++  S+L +     + D        E I+A ++      L+VV  VF
Sbjct: 32 EYEHAANCATHAFWIIPSILGSSNLYFLSDDDW-----ETISAWIYGLGLCGLFVVSTVF 86

Query: 90 SLIRWKSS 97
            I WK S
Sbjct: 87 HTISWKKS 94


>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
           isoform a [Homo sapiens]
          Length = 214

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 14/54 (25%), Positives = 23/54 (42%)

Query: 27  FIFEFDAAYHCTAALFYLSASVLEALATITMQDGFTYRHYHENIAAVVFSYIAT 80
           F F F   Y    A+F+ S+  L  +A I     +    +  NIA+   + + T
Sbjct: 83  FFFTFYTGYPIWGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGT 136


>gi|223278370 myeloid-associated differentiation marker-like 2 [Homo
           sapiens]
          Length = 307

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 9/65 (13%)

Query: 35  YHCTAALFYLSASVLEALATITMQDGFTYRH---------YHENIAAVVFSYIATLLYVV 85
           Y   A L YLSA+V+  +     + G   R          +   +   +F+Y+  LLYVV
Sbjct: 234 YTFLAVLLYLSAAVIWPVFCFDPKYGEPKRPPNCARGSCPWDSQLVVAIFTYVNLLLYVV 293

Query: 86  HAVFS 90
              +S
Sbjct: 294 DLAYS 298


>gi|13786129 RAB33B, member RAS oncogene family [Homo sapiens]
          Length = 229

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 12/29 (41%), Positives = 18/29 (62%)

Query: 64  RHYHENIAAVVFSYIATLLYVVHAVFSLI 92
           +HY+ N+ AVVF Y  T +   H++ S I
Sbjct: 101 QHYYRNVHAVVFVYDMTNMASFHSLPSWI 129


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.136    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,168,569
Number of Sequences: 37866
Number of extensions: 97472
Number of successful extensions: 318
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 295
Number of HSP's gapped (non-prelim): 28
length of query: 97
length of database: 18,247,518
effective HSP length: 68
effective length of query: 29
effective length of database: 15,672,630
effective search space: 454506270
effective search space used: 454506270
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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