Guide to the Human Genome
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Name: MITF Sequence: fasta or formatted (519aa) NCBI GI: 38156701
Description:

microphthalmia-associated transcription factor isoform 3

Referenced in:

Skin and Related Tissues
Helix-Loop-Helix Transcription Factors

Other entries for this name:
alt prot [413aa] microphthalmia-associated transcription factor isoform 5
alt prot [520aa] microphthalmia-associated transcription factor isoform 1
alt prot [504aa] microphthalmia-associated transcription factor isoform 2
alt prot [495aa] microphthalmia-associated transcription factor isoform 6
alt prot [419aa] microphthalmia-associated transcription factor isoform 4
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.6         29           2
 C cysteine            2.1         11           1
 D aspartate           4.0         21           2
 E glutamate           7.3         38           2
 F phenylalanine       1.5          8           1
 G glycine             4.0         21           1
 H histidine           2.7         14           2
 I isoleucine          4.6         24           2
 K lysine              5.0         26           2
 L leucine            11.0         57           3
 M methionine          3.9         20           1
 N asparagine          6.2         32           3
 P proline             6.7         35           3
 Q glutamine           7.3         38           3
 R arginine            6.0         31           4
 S serine              9.4         49           4
 T threonine           6.7         35           3
 V valine              4.2         22           2
 W tryptophan          0.2          1           1
 Y tyrosine            1.3          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   microphthalmia-associated transcription factor isofo... 
MITF                  0.938   microphthalmia-associated transcription factor isofo...
MITF                  0.935   microphthalmia-associated transcription factor isofo...
MITF                  0.934   microphthalmia-associated transcription factor isofo...
MITF                  0.779   microphthalmia-associated transcription factor isofo...
MITF                  0.773   microphthalmia-associated transcription factor isofor...
TFE3                  0.405   transcription factor E3 
TFEB                  0.329   transcription factor EB 
TFEC                  0.257   transcription factor EC isoform a 
TFEC                  0.238   transcription factor EC isoform b 
USF2                  0.034   upstream stimulatory factor 2 isoform 2 
USF2                  0.034   upstream stimulatory factor 2 isoform 1 
USF1                  0.031   upstream stimulatory factor 1 isoform 1 
USF1                  0.031   upstream stimulatory factor 1 isoform 2 
SREBF1                0.029   sterol regulatory element binding transcription fact...
SREBF1                0.029   sterol regulatory element binding transcription fact...
SREBF2                0.027   sterol regulatory element-binding transcription fact...
KIAA2018              0.027   hypothetical protein LOC205717 
ARNTL                 0.020   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.020   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.020   aryl hydrocarbon receptor nuclear translocator-like ...
EP400                 0.019   E1A binding protein p400 
CLOCK                 0.018   clock 
MXD4                  0.018   MAD4 
ARNTL2                0.017   aryl hydrocarbon receptor nuclear translocator-like ...
ARNT                  0.017   aryl hydrocarbon receptor nuclear translocator isofo...
ARNT                  0.017   aryl hydrocarbon receptor nuclear translocator isofor...
MYCN                  0.017   v-myc myelocytomatosis viral related oncogene, neuro...
RNASEN                0.017   ribonuclease III, nuclear isoform 1 
MED15                 0.016   mediator complex subunit 15 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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