Guide to the Human Genome
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Search of human proteins with 37577287

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
         (287 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]                       556   e-158
gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]                       525   e-149
gi|16418379 syntaxin 1B [Homo sapiens]                                370   e-103
gi|4759182 syntaxin 1A (brain) [Homo sapiens]                         366   e-101
gi|4759184 syntaxin 3 [Homo sapiens]                                  343   1e-94
gi|20149560 syntaxin 4 [Homo sapiens]                                 236   1e-62
gi|33667038 syntaxin 11 [Homo sapiens]                                169   3e-42
gi|49258196 syntaxin 19 [Homo sapiens]                                140   1e-33
gi|170932494 syntaxin 7 [Homo sapiens]                                 99   4e-21
gi|28933465 syntaxin 12 [Homo sapiens]                                 96   5e-20
gi|47778943 syntaxin 16 isoform a [Homo sapiens]                       71   1e-12
gi|198041692 syntaxin 16 isoform d [Homo sapiens]                      71   1e-12
gi|198041688 syntaxin 16 isoform c [Homo sapiens]                      71   1e-12
gi|34447229 syntaxin 16 isoform b [Homo sapiens]                       71   1e-12
gi|223972648 t-SNARE domain containing 1 [Homo sapiens]                58   8e-09
gi|94400932 syntaxin 5 [Homo sapiens]                                  52   8e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    49   4e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    49   4e-06
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    49   4e-06
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    49   4e-06
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    49   5e-06
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    49   5e-06
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    45   6e-05
gi|237858621 polyamine modulated factor 1 binding protein 1 isof...    44   1e-04
gi|237858619 polyamine modulated factor 1 binding protein 1 isof...    44   1e-04
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         44   2e-04
gi|31542634 filamin A interacting protein 1 [Homo sapiens]             44   2e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     43   3e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    43   3e-04
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    42   8e-04

>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
          Length = 287

 Score =  556 bits (1432), Expect = e-158
 Identities = 287/287 (100%), Positives = 287/287 (100%)

Query: 1   MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60
           MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII
Sbjct: 1   MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60

Query: 61  LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120
           LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS
Sbjct: 61  LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120

Query: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180
           VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI
Sbjct: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180

Query: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240
           ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT
Sbjct: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240

Query: 241 DYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTLS 287
           DYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTLS
Sbjct: 241 DYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTLS 287


>gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
          Length = 288

 Score =  525 bits (1352), Expect = e-149
 Identities = 269/286 (94%), Positives = 276/286 (96%)

Query: 1   MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60
           MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII
Sbjct: 1   MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60

Query: 61  LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120
           LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS
Sbjct: 61  LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120

Query: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180
           VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI
Sbjct: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180

Query: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240
           ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT
Sbjct: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240

Query: 241 DYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTL 286
           DYVEHAKEETKKAIKYQSKARRK   II   +VL+ I+ +I+  ++
Sbjct: 241 DYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSV 286


>gi|16418379 syntaxin 1B [Homo sapiens]
          Length = 288

 Score =  370 bits (951), Expect = e-103
 Identities = 186/286 (65%), Positives = 234/286 (81%)

Query: 1   MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60
           M+DR  +L + + +DD + VV V++DHFMD+FF QVEEIR  I+K+++ VE+VKK HS I
Sbjct: 1   MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAI 60

Query: 61  LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120
           L+APNP+ K K+ELEDL  +IKKTANK+R+KLKAIEQS +Q+E  NR+S DLRIR+TQHS
Sbjct: 61  LAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHS 120

Query: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180
            LSRKFVE M EYN  Q+ +R+R K RIQRQLEITGRTTT++ELE+MLESGK +IFT DI
Sbjct: 121 TLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDI 180

Query: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240
             DSQ+T+QALNEIE+RH +I+KLETSIRELH+MF+DMAM VE+QGEMI+ IE NV ++ 
Sbjct: 181 KMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSV 240

Query: 241 DYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTL 286
           DYVE A  +TKKA+KYQSKARRK + IIIC +VL V+L   +  TL
Sbjct: 241 DYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTL 286


>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
          Length = 288

 Score =  366 bits (939), Expect = e-101
 Identities = 189/287 (65%), Positives = 232/287 (80%), Gaps = 5/287 (1%)

Query: 1   MRDRLPDL-TACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSI 59
           M+DR  +L TA   +DD D  V V++D FMD+FF QVEEIR  IDKI + VEEVK+ HS 
Sbjct: 1   MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA 60

Query: 60  ILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQH 119
           IL++PNP+ K KEELE+L  +IKKTANK+R+KLK+IEQS +Q+E  NR+S DLRIR+TQH
Sbjct: 61  ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH 120

Query: 120 SVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSD 179
           S LSRKFVE M+EYN  Q+ +RER KGRIQRQLEITGRTTT +ELE+MLESG P+IF S 
Sbjct: 121 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG 180

Query: 180 IISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNA 239
           II DS I++QAL+EIE+RH +I+KLE SIRELH+MFMDMAM VE+QGEMI+ IE NV +A
Sbjct: 181 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA 240

Query: 240 TDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTL 286
            DYVE A  +TKKA+KYQSKARRK + IIIC     VILGI++A+T+
Sbjct: 241 VDYVERAVSDTKKAVKYQSKARRKKIMIIIC----CVILGIVIASTV 283


>gi|4759184 syntaxin 3 [Homo sapiens]
          Length = 289

 Score =  343 bits (880), Expect = 1e-94
 Identities = 180/289 (62%), Positives = 232/289 (80%), Gaps = 6/289 (2%)

Query: 1   MRDRLPDLTACRKNDDGDTVVV---VEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNH 57
           M+DRL  L A +   D DT  V   ++   FMD+FF ++EE R +IDKI+++VEE KK +
Sbjct: 1   MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60

Query: 58  SIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRT 117
           SIILSAP PE K K++LE L  EIKK AN +R KLK++E+  ++DE   R+S DLRIR++
Sbjct: 61  SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEV--RSSADLRIRKS 118

Query: 118 QHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFT 177
           QHSVLSRKFVE M +YNEAQ  FRERSKGRIQRQLEITG+ TTD+ELEEMLESG P+IFT
Sbjct: 119 QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFT 178

Query: 178 SDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVM 237
           S II DSQI++QAL+EIE RHKDI++LE+SI+ELH+MFMD+AM VE QGEM++NIE NVM
Sbjct: 179 SGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVM 237

Query: 238 NATDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTL 286
           +  D+VE A++ETKKA+KYQS+AR+KL+ II+ V+VLL IL +I+  ++
Sbjct: 238 HTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSV 286


>gi|20149560 syntaxin 4 [Homo sapiens]
          Length = 297

 Score =  236 bits (603), Expect = 1e-62
 Identities = 123/259 (47%), Positives = 186/259 (71%), Gaps = 4/259 (1%)

Query: 30  DDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIR 89
           ++FFH+V  IR +I K+   V+E++K    IL+ P PE  +K+EL++L  EIK+   +IR
Sbjct: 39  EEFFHKVRTIRQTIVKLGNKVQELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIR 98

Query: 90  AKLKAIE-QSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRI 148
            +LKAIE Q  + DE+ N  SV+ R+R+TQH VLS++FVE + + N  Q+ +RE++  RI
Sbjct: 99  LQLKAIEPQKEEADENYN--SVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERI 156

Query: 149 QRQLEITGR-TTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETS 207
           +RQL+IT     +D+ELE+ML+SG+  +F S+I+ D+Q+TRQALNEI +RH +I +LE S
Sbjct: 157 RRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERS 216

Query: 208 IRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFI 267
           IRELH++F  +A  VE QGEMIN IE+N++++ DYVE  +E  K A++ Q KAR+K + I
Sbjct: 217 IRELHDIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLI 276

Query: 268 IICVIVLLVILGIILATTL 286
            ICV + +V+L +I+  T+
Sbjct: 277 AICVSITVVLLAVIIGVTV 295


>gi|33667038 syntaxin 11 [Homo sapiens]
          Length = 287

 Score =  169 bits (428), Expect = 3e-42
 Identities = 94/283 (33%), Positives = 159/283 (56%), Gaps = 13/283 (4%)

Query: 1   MRDRLPDLTACRKN-----DDGDTV-------VVVEKDHFMDDFFHQVEEIRNSIDKITQ 48
           M+DRL +L    K       DGD         +V E DH ++  +  + +I++    +  
Sbjct: 1   MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60

Query: 49  YVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRT 108
            V+ + K ++  L++      IK +   + K IK     I  KL+A+++  +  E+ +  
Sbjct: 61  DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120

Query: 109 -SVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEM 167
            S   RI R Q++ L+  F  AM +YN+A+   R+  K RIQRQLEI G+  + D++E+M
Sbjct: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180

Query: 168 LESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGE 227
            E GK  +F+ ++++D +  R ALNEIESRH+++++LE+ IR++HE+F+ MA+ VE Q +
Sbjct: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240

Query: 228 MINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIIC 270
            +N IE NV    DY   AK + +KA++Y+ K   + +    C
Sbjct: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCC 283


>gi|49258196 syntaxin 19 [Homo sapiens]
          Length = 294

 Score =  140 bits (353), Expect = 1e-33
 Identities = 73/240 (30%), Positives = 139/240 (57%), Gaps = 2/240 (0%)

Query: 21  VVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE 80
           V+ E++   +   H++++++ SI+ +   V++  +    ++++      +K E   + KE
Sbjct: 39  VIYEREPVAERHLHEIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRE-STITKE 97

Query: 81  IKKTANKIRAKLKAIEQSFDQDESGNR-TSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTL 139
           IK  A  I   L  + +   + E  N  +SV  RI ++QH+ + R F + M  YN+    
Sbjct: 98  IKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAA 157

Query: 140 FRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHK 199
            +E+ K  I RQLE+ G+  +++++ +ML  GK  +F   ++++  IT+  L+EIE RHK
Sbjct: 158 KQEKCKTFILRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHK 217

Query: 200 DIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSK 259
           +++ LE  I++L ++F+ +++ VE QGE INNIE  V +  +YV + KE+   A+KY+ +
Sbjct: 218 ELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKR 277


>gi|170932494 syntaxin 7 [Homo sapiens]
          Length = 261

 Score = 99.0 bits (245), Expect = 4e-21
 Identities = 64/253 (25%), Positives = 124/253 (49%), Gaps = 16/253 (6%)

Query: 37  EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE 96
           + I ++I KITQ   E+++  +  L  P    +++++L+   +   + A       K  +
Sbjct: 16  QRISSNIQKITQCSVEIQRTLNQ-LGTPQDSPELRQQLQQKQQYTNQLA-------KETD 67

Query: 97  QSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSK---GRIQRQLE 153
           +   +  S   T  + R R+ Q   L  +F  ++  + + Q    ER K    R++    
Sbjct: 68  KYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSR 127

Query: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHE 213
           ++G    D   E  L S +        + D +IT   L  I  R   I +LE  I +++E
Sbjct: 128 VSGSFPEDSSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINE 187

Query: 214 MFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICVIV 273
           +F D+ M +  QG++I++IE NV NA  +V+ A ++  +A  YQ K+R+ L     C+I+
Sbjct: 188 IFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTL-----CIII 242

Query: 274 LLVILGIILATTL 286
           L++++G+ + + +
Sbjct: 243 LILVIGVAIISLI 255


>gi|28933465 syntaxin 12 [Homo sapiens]
          Length = 276

 Score = 95.5 bits (236), Expect = 5e-20
 Identities = 68/258 (26%), Positives = 126/258 (48%), Gaps = 15/258 (5%)

Query: 31  DFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLN---KEIKKTANK 87
           DF   ++    +I +I+Q   ++K N    L       K++E L+ L     ++ K  N+
Sbjct: 21  DFSSIIQTCSGNIQRISQATAQIK-NLMSQLGTKQDSSKLQENLQQLQHSTNQLAKETNE 79

Query: 88  IRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGR 147
           +  +L ++       E         R +R Q   L   F  A+  +   Q    E+ K  
Sbjct: 80  LLKELGSLPLPLSTSEQ--------RQQRLQKERLMNDFSAALNNFQAVQRRVSEKEKES 131

Query: 148 IQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQ---ITRQALNEIESRHKDIMKL 204
           I R    +  +  + + EE L S       + + S      IT Q L  I+ R   I +L
Sbjct: 132 IARARAGSRLSAEERQREEQLVSFDSHEEWNQMQSQEDEVAITEQDLELIKERETAIRQL 191

Query: 205 ETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKL 264
           E  I +++++F D+AM +  QG++I++IE NV ++  +VE A E+ ++A  YQ K+R+K+
Sbjct: 192 EADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKM 251

Query: 265 MFIIICVIVLLVILGIIL 282
             +++ + V+++ILG+I+
Sbjct: 252 CILVLVLSVIILILGLII 269


>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
          Length = 325

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 54/250 (21%), Positives = 121/250 (48%), Gaps = 15/250 (6%)

Query: 36  VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
           V+EI+  + +I Q ++E+   H   L+ P  +   +EE  +E   +EI +  ++ +  ++
Sbjct: 82  VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 141

Query: 94  AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
           A+        +   +  + R+     + L++   E    +  AQ+ + +R K R +R   
Sbjct: 142 ALPS-----RARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 196

Query: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
                   D    +++ G  +       ++ Q+     N   +E R ++I ++  SI +L
Sbjct: 197 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 250

Query: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICV 271
           +E+F D+   +  QG +++ I+ NV  +    E   ++  KA +YQ K R+ L+ +I+ V
Sbjct: 251 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFV 310

Query: 272 IVLLVILGII 281
           I++++I+ ++
Sbjct: 311 IIIVLIVVLV 320


>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
          Length = 308

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 54/250 (21%), Positives = 121/250 (48%), Gaps = 15/250 (6%)

Query: 36  VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
           V+EI+  + +I Q ++E+   H   L+ P  +   +EE  +E   +EI +  ++ +  ++
Sbjct: 65  VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 124

Query: 94  AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
           A+        +   +  + R+     + L++   E    +  AQ+ + +R K R +R   
Sbjct: 125 ALPS-----RARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 179

Query: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
                   D    +++ G  +       ++ Q+     N   +E R ++I ++  SI +L
Sbjct: 180 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 233

Query: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICV 271
           +E+F D+   +  QG +++ I+ NV  +    E   ++  KA +YQ K R+ L+ +I+ V
Sbjct: 234 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFV 293

Query: 272 IVLLVILGII 281
           I++++I+ ++
Sbjct: 294 IIIVLIVVLV 303


>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
          Length = 321

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 54/250 (21%), Positives = 121/250 (48%), Gaps = 15/250 (6%)

Query: 36  VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
           V+EI+  + +I Q ++E+   H   L+ P  +   +EE  +E   +EI +  ++ +  ++
Sbjct: 78  VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 137

Query: 94  AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
           A+        +   +  + R+     + L++   E    +  AQ+ + +R K R +R   
Sbjct: 138 ALPS-----RARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 192

Query: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
                   D    +++ G  +       ++ Q+     N   +E R ++I ++  SI +L
Sbjct: 193 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 246

Query: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICV 271
           +E+F D+   +  QG +++ I+ NV  +    E   ++  KA +YQ K R+ L+ +I+ V
Sbjct: 247 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFV 306

Query: 272 IVLLVILGII 281
           I++++I+ ++
Sbjct: 307 IIIVLIVVLV 316


>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
          Length = 304

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 54/250 (21%), Positives = 121/250 (48%), Gaps = 15/250 (6%)

Query: 36  VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
           V+EI+  + +I Q ++E+   H   L+ P  +   +EE  +E   +EI +  ++ +  ++
Sbjct: 61  VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 120

Query: 94  AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
           A+        +   +  + R+     + L++   E    +  AQ+ + +R K R +R   
Sbjct: 121 ALPS-----RARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 175

Query: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
                   D    +++ G  +       ++ Q+     N   +E R ++I ++  SI +L
Sbjct: 176 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 229

Query: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICV 271
           +E+F D+   +  QG +++ I+ NV  +    E   ++  KA +YQ K R+ L+ +I+ V
Sbjct: 230 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFV 289

Query: 272 IVLLVILGII 281
           I++++I+ ++
Sbjct: 290 IIIVLIVVLV 299


>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
          Length = 513

 Score = 58.2 bits (139), Expect = 8e-09
 Identities = 58/263 (22%), Positives = 127/263 (48%), Gaps = 26/263 (9%)

Query: 37  EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEEL----EDLNKEIKKTANKIRAKL 92
           +E+  ++ +I   V  ++++    L  P+   ++++ L    ++ NK I  +A+ ++   
Sbjct: 262 QEMSANVFRINSSVTSLERSLQS-LGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMA 320

Query: 93  KAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQL 152
           + +  S  Q+         L+  R Q   L  +  +A+  Y   Q    E+S+  +    
Sbjct: 321 ELLRSSCPQER--------LQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLP-MA 371

Query: 153 EITGRTTTDDELEEMLESGKPSIFT-SDIISDSQ-------ITRQALNEIESRHKDIMKL 204
           +   + +      E+ +  K  +F  SD +   Q       IT + L  I  R + I+++
Sbjct: 372 QRGSKQSPQAPFAELADDEK--VFNGSDNMWQGQEQALLPDITEEDLEAIRLREEAILQM 429

Query: 205 ETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARR-K 263
           E+++ +++++  D+A  V  QGE +++IE ++  A+ + E A++    A ++Q +  + K
Sbjct: 430 ESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRHKIK 489

Query: 264 LMFIIICVIVLLVILGIILATTL 286
             F+   V  LLVI+ II+AT++
Sbjct: 490 CCFLSAGVTALLVII-IIIATSV 511


>gi|94400932 syntaxin 5 [Homo sapiens]
          Length = 355

 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 55/224 (24%), Positives = 98/224 (43%), Gaps = 17/224 (7%)

Query: 70  IKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEA 129
           IK+++  LNK+I +  + +RA  K  +         N   V L+ +    S   +  +E 
Sbjct: 139 IKQDINSLNKQIAQLQDFVRA--KGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEV 196

Query: 130 MAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDEL-EEMLESGKPSIFTSDIISDSQITR 188
             E      L ++RS+     +  ++      + L    +  G  S  + D+  D   +R
Sbjct: 197 RTE-----NLKQQRSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHASKDVAIDMMDSR 251

Query: 189 -----QALNE----IESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNA 239
                Q ++E    I+SR   +  +E++I EL  +F  +A  V+ Q E I  I+ NV+ A
Sbjct: 252 TSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGA 311

Query: 240 TDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILA 283
              VE A  E  K  +  +  R  ++ I + +IV  +I  + LA
Sbjct: 312 QLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA 355


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 45/227 (19%), Positives = 99/227 (43%), Gaps = 16/227 (7%)

Query: 37   EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE------IKKTANKIRA 90
            EE++ ++ ++    +E+ + ++ +      EG I +  EDL+ E       +K    +  
Sbjct: 1090 EELQAALARLD---DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1146

Query: 91   KLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQR 150
            +L+A++   +       T  +LR +R Q   + +K ++     +EAQ   +E  +   Q 
Sbjct: 1147 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQV--QEMRQKHAQA 1204

Query: 151  QLEITGRTTTDDELEEMLESGKPSI--FTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
              E+T +       +  L+  K ++    +D+  + ++  QA  E+E + K   KLE  +
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK---KLEAQV 1261

Query: 209  RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIK 255
            +EL     D         + ++ ++  V + T  +  A+ +  K  K
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308



 Score = 37.0 bits (84), Expect = 0.020
 Identities = 52/264 (19%), Positives = 105/264 (39%), Gaps = 38/264 (14%)

Query: 29   MDDFFHQVEEIRNSIDKITQYVEEVKKN-----------HSIILSAPNPEGKIKEELEDL 77
            M DF  ++E+ R S D+I    +E +K               + +A     +   E E+L
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713

Query: 78   NKEIKKTAN----------KIRAKLKAIEQSFDQDESGNRTSVDLRIRRT--QHSVLSRK 125
             +E+  + +          ++ A++  +E+   ++E GN  ++  R+R+   Q   LS +
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE 1772

Query: 126  FV--EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISD 183
                 + A+ NE+     ER    ++ +L          E+E  ++S   S   +     
Sbjct: 1773 LATERSTAQKNESARQQLERQNKELRSKLH---------EMEGAVKSKFKSTIAALEAKI 1823

Query: 184  SQITRQALNEIESRHKDIMKLETSIRELHEMFM---DMAMFVETQGEMINNIERNVMNAT 240
            +Q+  Q   E   +      L+   ++L E+ +   D     E   E        V    
Sbjct: 1824 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1883

Query: 241  DYVEHAKEETKKAIKYQSKARRKL 264
              +E A+EE+++    + K +R+L
Sbjct: 1884 RQLEEAEEESQRINANRRKLQREL 1907



 Score = 36.6 bits (83), Expect = 0.026
 Identities = 36/241 (14%), Positives = 100/241 (41%), Gaps = 11/241 (4%)

Query: 29   MDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKI 88
            +++   Q+E+ + +   + +  + ++K ++ +       G+ K+E+E   K+++    ++
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264

Query: 89   RAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRI 148
            ++K    E++        R  ++ ++ + Q+ V S   V  M    E + +   +    +
Sbjct: 1265 QSKCSDGERA--------RAELNDKVHKLQNEVES---VTGMLNEAEGKAIKLAKDVASL 1313

Query: 149  QRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
              QL+ T     ++  +++  S K      +  S      + +   ++  + I  L   +
Sbjct: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373

Query: 209  RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFII 268
             +  +   D A  VE   E     ++ + N T   E       K  K +++ +++L  ++
Sbjct: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433

Query: 269  I 269
            +
Sbjct: 1434 V 1434



 Score = 33.5 bits (75), Expect = 0.22
 Identities = 35/222 (15%), Positives = 85/222 (38%), Gaps = 26/222 (11%)

Query: 36   VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAI 95
            +E + + + K TQ  E++    +   S        +++LE  NKE       +R+KL  +
Sbjct: 1752 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE-------LRSKLHEM 1804

Query: 96   EQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEIT 155
            E +          +++ +I + +  V      +   E   A    +++ K   +  L++ 
Sbjct: 1805 EGAVKSKFKSTIAALEAKIAQLEEQV-----EQEAREKQAATKSLKQKDKKLKEILLQVE 1859

Query: 156  GRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMF 215
                  ++ +E  E G   +            +Q   ++E   ++  ++  + R+L    
Sbjct: 1860 DERKMAEQYKEQAEKGNARV------------KQLKRQLEEAEEESQRINANRRKLQREL 1907

Query: 216  MDMAMFVETQGEMINNIERNVM--NATDYVEHAKEETKKAIK 255
             +     E  G  +N ++  +   N T +V   +   ++ I+
Sbjct: 1908 DEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIE 1949



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 39/204 (19%), Positives = 88/204 (43%), Gaps = 14/204 (6%)

Query: 51   EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSV 110
            EE + + + +        +  EEL +  ++ K+     +A L   +Q+ +++ +    + 
Sbjct: 1185 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA----KANLDKNKQTLEKENAD--LAG 1238

Query: 111  DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLES 170
            +LR+       +  K  +  A+  E Q+   +  + R +   ++       + +  ML  
Sbjct: 1239 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1298

Query: 171  --GKPSIFTSDIISDS---QITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQ 225
              GK      D+ S S   Q T++ L E E+R K  + + T +R+L E    +   ++ +
Sbjct: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQE-ETRQK--LNVSTKLRQLEEERNSLQDQLDEE 1355

Query: 226  GEMINNIERNVMNATDYVEHAKEE 249
             E   N+ER++      +  +K++
Sbjct: 1356 MEAKQNLERHISTLNIQLSDSKKK 1379



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 38/250 (15%), Positives = 102/250 (40%), Gaps = 29/250 (11%)

Query: 25   KDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKT 84
            K+    +    V ++ N    ++   ++ +K   ++    N   K  +E +    E ++ 
Sbjct: 1422 KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1481

Query: 85   ANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERS 144
              K  +  +A+E++ +  E   RT          + +L  +  + ++  ++      E  
Sbjct: 1482 ETKALSLARALEEALEAKEELERT----------NKMLKAEMEDLVSSKDDVGKNVHELE 1531

Query: 145  KGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQAL-----NEIESRHK 199
            K +   + ++    T  +ELE+ L++      T D     ++  QAL      ++++R +
Sbjct: 1532 KSKRALETQMEEMKTQLEELEDELQA------TEDAKLRLEVNMQALKGQFERDLQARDE 1585

Query: 200  DIMKLETSI-RELHEMFMDM-------AMFVETQGEMINNIERNVMNATDYVEHAKEETK 251
               +    + R+LHE   ++       A+    + ++  +++   + A   ++  +E  K
Sbjct: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645

Query: 252  KAIKYQSKAR 261
            +  K Q++ +
Sbjct: 1646 QLRKLQAQMK 1655


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 45/227 (19%), Positives = 99/227 (43%), Gaps = 16/227 (7%)

Query: 37   EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE------IKKTANKIRA 90
            EE++ ++ ++    +E+ + ++ +      EG I +  EDL+ E       +K    +  
Sbjct: 1097 EELQAALARLD---DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1153

Query: 91   KLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQR 150
            +L+A++   +       T  +LR +R Q   + +K ++     +EAQ   +E  +   Q 
Sbjct: 1154 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQV--QEMRQKHAQA 1211

Query: 151  QLEITGRTTTDDELEEMLESGKPSI--FTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
              E+T +       +  L+  K ++    +D+  + ++  QA  E+E + K   KLE  +
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK---KLEAQV 1268

Query: 209  RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIK 255
            +EL     D         + ++ ++  V + T  +  A+ +  K  K
Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1315



 Score = 37.0 bits (84), Expect = 0.020
 Identities = 52/264 (19%), Positives = 105/264 (39%), Gaps = 38/264 (14%)

Query: 29   MDDFFHQVEEIRNSIDKITQYVEEVKKN-----------HSIILSAPNPEGKIKEELEDL 77
            M DF  ++E+ R S D+I    +E +K               + +A     +   E E+L
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720

Query: 78   NKEIKKTAN----------KIRAKLKAIEQSFDQDESGNRTSVDLRIRRT--QHSVLSRK 125
             +E+  + +          ++ A++  +E+   ++E GN  ++  R+R+   Q   LS +
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE 1779

Query: 126  FV--EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISD 183
                 + A+ NE+     ER    ++ +L          E+E  ++S   S   +     
Sbjct: 1780 LATERSTAQKNESARQQLERQNKELRSKLH---------EMEGAVKSKFKSTIAALEAKI 1830

Query: 184  SQITRQALNEIESRHKDIMKLETSIRELHEMFM---DMAMFVETQGEMINNIERNVMNAT 240
            +Q+  Q   E   +      L+   ++L E+ +   D     E   E        V    
Sbjct: 1831 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1890

Query: 241  DYVEHAKEETKKAIKYQSKARRKL 264
              +E A+EE+++    + K +R+L
Sbjct: 1891 RQLEEAEEESQRINANRRKLQREL 1914



 Score = 36.6 bits (83), Expect = 0.026
 Identities = 36/241 (14%), Positives = 100/241 (41%), Gaps = 11/241 (4%)

Query: 29   MDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKI 88
            +++   Q+E+ + +   + +  + ++K ++ +       G+ K+E+E   K+++    ++
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271

Query: 89   RAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRI 148
            ++K    E++        R  ++ ++ + Q+ V S   V  M    E + +   +    +
Sbjct: 1272 QSKCSDGERA--------RAELNDKVHKLQNEVES---VTGMLNEAEGKAIKLAKDVASL 1320

Query: 149  QRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
              QL+ T     ++  +++  S K      +  S      + +   ++  + I  L   +
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380

Query: 209  RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFII 268
             +  +   D A  VE   E     ++ + N T   E       K  K +++ +++L  ++
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1440

Query: 269  I 269
            +
Sbjct: 1441 V 1441



 Score = 33.5 bits (75), Expect = 0.22
 Identities = 35/222 (15%), Positives = 85/222 (38%), Gaps = 26/222 (11%)

Query: 36   VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAI 95
            +E + + + K TQ  E++    +   S        +++LE  NKE       +R+KL  +
Sbjct: 1759 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE-------LRSKLHEM 1811

Query: 96   EQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEIT 155
            E +          +++ +I + +  V      +   E   A    +++ K   +  L++ 
Sbjct: 1812 EGAVKSKFKSTIAALEAKIAQLEEQV-----EQEAREKQAATKSLKQKDKKLKEILLQVE 1866

Query: 156  GRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMF 215
                  ++ +E  E G   +            +Q   ++E   ++  ++  + R+L    
Sbjct: 1867 DERKMAEQYKEQAEKGNARV------------KQLKRQLEEAEEESQRINANRRKLQREL 1914

Query: 216  MDMAMFVETQGEMINNIERNVM--NATDYVEHAKEETKKAIK 255
             +     E  G  +N ++  +   N T +V   +   ++ I+
Sbjct: 1915 DEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIE 1956



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 39/204 (19%), Positives = 88/204 (43%), Gaps = 14/204 (6%)

Query: 51   EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSV 110
            EE + + + +        +  EEL +  ++ K+     +A L   +Q+ +++ +    + 
Sbjct: 1192 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA----KANLDKNKQTLEKENAD--LAG 1245

Query: 111  DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLES 170
            +LR+       +  K  +  A+  E Q+   +  + R +   ++       + +  ML  
Sbjct: 1246 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1305

Query: 171  --GKPSIFTSDIISDS---QITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQ 225
              GK      D+ S S   Q T++ L E E+R K  + + T +R+L E    +   ++ +
Sbjct: 1306 AEGKAIKLAKDVASLSSQLQDTQELLQE-ETRQK--LNVSTKLRQLEEERNSLQDQLDEE 1362

Query: 226  GEMINNIERNVMNATDYVEHAKEE 249
             E   N+ER++      +  +K++
Sbjct: 1363 MEAKQNLERHISTLNIQLSDSKKK 1386



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 38/250 (15%), Positives = 102/250 (40%), Gaps = 29/250 (11%)

Query: 25   KDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKT 84
            K+    +    V ++ N    ++   ++ +K   ++    N   K  +E +    E ++ 
Sbjct: 1429 KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1488

Query: 85   ANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERS 144
              K  +  +A+E++ +  E   RT          + +L  +  + ++  ++      E  
Sbjct: 1489 ETKALSLARALEEALEAKEELERT----------NKMLKAEMEDLVSSKDDVGKNVHELE 1538

Query: 145  KGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQAL-----NEIESRHK 199
            K +   + ++    T  +ELE+ L++      T D     ++  QAL      ++++R +
Sbjct: 1539 KSKRALETQMEEMKTQLEELEDELQA------TEDAKLRLEVNMQALKGQFERDLQARDE 1592

Query: 200  DIMKLETSI-RELHEMFMDM-------AMFVETQGEMINNIERNVMNATDYVEHAKEETK 251
               +    + R+LHE   ++       A+    + ++  +++   + A   ++  +E  K
Sbjct: 1593 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652

Query: 252  KAIKYQSKAR 261
            +  K Q++ +
Sbjct: 1653 QLRKLQAQMK 1662


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 45/227 (19%), Positives = 99/227 (43%), Gaps = 16/227 (7%)

Query: 37   EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE------IKKTANKIRA 90
            EE++ ++ ++    +E+ + ++ +      EG I +  EDL+ E       +K    +  
Sbjct: 1097 EELQAALARLD---DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1153

Query: 91   KLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQR 150
            +L+A++   +       T  +LR +R Q   + +K ++     +EAQ   +E  +   Q 
Sbjct: 1154 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQV--QEMRQKHAQA 1211

Query: 151  QLEITGRTTTDDELEEMLESGKPSI--FTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
              E+T +       +  L+  K ++    +D+  + ++  QA  E+E + K   KLE  +
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK---KLEAQV 1268

Query: 209  RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIK 255
            +EL     D         + ++ ++  V + T  +  A+ +  K  K
Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1315



 Score = 37.0 bits (84), Expect = 0.020
 Identities = 52/264 (19%), Positives = 105/264 (39%), Gaps = 38/264 (14%)

Query: 29   MDDFFHQVEEIRNSIDKITQYVEEVKKN-----------HSIILSAPNPEGKIKEELEDL 77
            M DF  ++E+ R S D+I    +E +K               + +A     +   E E+L
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720

Query: 78   NKEIKKTAN----------KIRAKLKAIEQSFDQDESGNRTSVDLRIRRT--QHSVLSRK 125
             +E+  + +          ++ A++  +E+   ++E GN  ++  R+R+   Q   LS +
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE 1779

Query: 126  FV--EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISD 183
                 + A+ NE+     ER    ++ +L          E+E  ++S   S   +     
Sbjct: 1780 LATERSTAQKNESARQQLERQNKELRSKLH---------EMEGAVKSKFKSTIAALEAKI 1830

Query: 184  SQITRQALNEIESRHKDIMKLETSIRELHEMFM---DMAMFVETQGEMINNIERNVMNAT 240
            +Q+  Q   E   +      L+   ++L E+ +   D     E   E        V    
Sbjct: 1831 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1890

Query: 241  DYVEHAKEETKKAIKYQSKARRKL 264
              +E A+EE+++    + K +R+L
Sbjct: 1891 RQLEEAEEESQRINANRRKLQREL 1914



 Score = 36.6 bits (83), Expect = 0.026
 Identities = 36/241 (14%), Positives = 100/241 (41%), Gaps = 11/241 (4%)

Query: 29   MDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKI 88
            +++   Q+E+ + +   + +  + ++K ++ +       G+ K+E+E   K+++    ++
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271

Query: 89   RAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRI 148
            ++K    E++        R  ++ ++ + Q+ V S   V  M    E + +   +    +
Sbjct: 1272 QSKCSDGERA--------RAELNDKVHKLQNEVES---VTGMLNEAEGKAIKLAKDVASL 1320

Query: 149  QRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
              QL+ T     ++  +++  S K      +  S      + +   ++  + I  L   +
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380

Query: 209  RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFII 268
             +  +   D A  VE   E     ++ + N T   E       K  K +++ +++L  ++
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1440

Query: 269  I 269
            +
Sbjct: 1441 V 1441



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 39/204 (19%), Positives = 88/204 (43%), Gaps = 14/204 (6%)

Query: 51   EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSV 110
            EE + + + +        +  EEL +  ++ K+     +A L   +Q+ +++ +    + 
Sbjct: 1192 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA----KANLDKNKQTLEKENAD--LAG 1245

Query: 111  DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLES 170
            +LR+       +  K  +  A+  E Q+   +  + R +   ++       + +  ML  
Sbjct: 1246 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1305

Query: 171  --GKPSIFTSDIISDS---QITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQ 225
              GK      D+ S S   Q T++ L E E+R K  + + T +R+L E    +   ++ +
Sbjct: 1306 AEGKAIKLAKDVASLSSQLQDTQELLQE-ETRQK--LNVSTKLRQLEEERNSLQDQLDEE 1362

Query: 226  GEMINNIERNVMNATDYVEHAKEE 249
             E   N+ER++      +  +K++
Sbjct: 1363 MEAKQNLERHISTLNIQLSDSKKK 1386



 Score = 30.8 bits (68), Expect = 1.4
 Identities = 31/198 (15%), Positives = 75/198 (37%), Gaps = 24/198 (12%)

Query: 36   VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAI 95
            +E + + + K TQ  E++    +   S        +++LE  NKE       +R+KL  +
Sbjct: 1759 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE-------LRSKLHEM 1811

Query: 96   EQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEIT 155
            E +          +++ +I + +  V      +   E   A    +++ K   +  L++ 
Sbjct: 1812 EGAVKSKFKSTIAALEAKIAQLEEQV-----EQEAREKQAATKSLKQKDKKLKEILLQVE 1866

Query: 156  GRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMF 215
                  ++ +E  E G   +            +Q   ++E   ++  ++  + R+L    
Sbjct: 1867 DERKMAEQYKEQAEKGNARV------------KQLKRQLEEAEEESQRINANRRKLQREL 1914

Query: 216  MDMAMFVETQGEMINNIE 233
             +     E  G  +N ++
Sbjct: 1915 DEATESNEAMGREVNALK 1932



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 38/250 (15%), Positives = 102/250 (40%), Gaps = 29/250 (11%)

Query: 25   KDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKT 84
            K+    +    V ++ N    ++   ++ +K   ++    N   K  +E +    E ++ 
Sbjct: 1429 KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1488

Query: 85   ANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERS 144
              K  +  +A+E++ +  E   RT          + +L  +  + ++  ++      E  
Sbjct: 1489 ETKALSLARALEEALEAKEELERT----------NKMLKAEMEDLVSSKDDVGKNVHELE 1538

Query: 145  KGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQAL-----NEIESRHK 199
            K +   + ++    T  +ELE+ L++      T D     ++  QAL      ++++R +
Sbjct: 1539 KSKRALETQMEEMKTQLEELEDELQA------TEDAKLRLEVNMQALKGQFERDLQARDE 1592

Query: 200  DIMKLETSI-RELHEMFMDM-------AMFVETQGEMINNIERNVMNATDYVEHAKEETK 251
               +    + R+LHE   ++       A+    + ++  +++   + A   ++  +E  K
Sbjct: 1593 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652

Query: 252  KAIKYQSKAR 261
            +  K Q++ +
Sbjct: 1653 QLRKLQAQMK 1662


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 45/227 (19%), Positives = 99/227 (43%), Gaps = 16/227 (7%)

Query: 37   EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE------IKKTANKIRA 90
            EE++ ++ ++    +E+ + ++ +      EG I +  EDL+ E       +K    +  
Sbjct: 1090 EELQAALARLD---DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1146

Query: 91   KLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQR 150
            +L+A++   +       T  +LR +R Q   + +K ++     +EAQ   +E  +   Q 
Sbjct: 1147 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQV--QEMRQKHAQA 1204

Query: 151  QLEITGRTTTDDELEEMLESGKPSI--FTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
              E+T +       +  L+  K ++    +D+  + ++  QA  E+E + K   KLE  +
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK---KLEAQV 1261

Query: 209  RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIK 255
            +EL     D         + ++ ++  V + T  +  A+ +  K  K
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308



 Score = 37.0 bits (84), Expect = 0.020
 Identities = 52/264 (19%), Positives = 105/264 (39%), Gaps = 38/264 (14%)

Query: 29   MDDFFHQVEEIRNSIDKITQYVEEVKKN-----------HSIILSAPNPEGKIKEELEDL 77
            M DF  ++E+ R S D+I    +E +K               + +A     +   E E+L
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713

Query: 78   NKEIKKTAN----------KIRAKLKAIEQSFDQDESGNRTSVDLRIRRT--QHSVLSRK 125
             +E+  + +          ++ A++  +E+   ++E GN  ++  R+R+   Q   LS +
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE 1772

Query: 126  FV--EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISD 183
                 + A+ NE+     ER    ++ +L          E+E  ++S   S   +     
Sbjct: 1773 LATERSTAQKNESARQQLERQNKELRSKLH---------EMEGAVKSKFKSTIAALEAKI 1823

Query: 184  SQITRQALNEIESRHKDIMKLETSIRELHEMFM---DMAMFVETQGEMINNIERNVMNAT 240
            +Q+  Q   E   +      L+   ++L E+ +   D     E   E        V    
Sbjct: 1824 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1883

Query: 241  DYVEHAKEETKKAIKYQSKARRKL 264
              +E A+EE+++    + K +R+L
Sbjct: 1884 RQLEEAEEESQRINANRRKLQREL 1907



 Score = 36.6 bits (83), Expect = 0.026
 Identities = 36/241 (14%), Positives = 100/241 (41%), Gaps = 11/241 (4%)

Query: 29   MDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKI 88
            +++   Q+E+ + +   + +  + ++K ++ +       G+ K+E+E   K+++    ++
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264

Query: 89   RAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRI 148
            ++K    E++        R  ++ ++ + Q+ V S   V  M    E + +   +    +
Sbjct: 1265 QSKCSDGERA--------RAELNDKVHKLQNEVES---VTGMLNEAEGKAIKLAKDVASL 1313

Query: 149  QRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
              QL+ T     ++  +++  S K      +  S      + +   ++  + I  L   +
Sbjct: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373

Query: 209  RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFII 268
             +  +   D A  VE   E     ++ + N T   E       K  K +++ +++L  ++
Sbjct: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433

Query: 269  I 269
            +
Sbjct: 1434 V 1434



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 39/204 (19%), Positives = 88/204 (43%), Gaps = 14/204 (6%)

Query: 51   EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSV 110
            EE + + + +        +  EEL +  ++ K+     +A L   +Q+ +++ +    + 
Sbjct: 1185 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA----KANLDKNKQTLEKENAD--LAG 1238

Query: 111  DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLES 170
            +LR+       +  K  +  A+  E Q+   +  + R +   ++       + +  ML  
Sbjct: 1239 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1298

Query: 171  --GKPSIFTSDIISDS---QITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQ 225
              GK      D+ S S   Q T++ L E E+R K  + + T +R+L E    +   ++ +
Sbjct: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQE-ETRQK--LNVSTKLRQLEEERNSLQDQLDEE 1355

Query: 226  GEMINNIERNVMNATDYVEHAKEE 249
             E   N+ER++      +  +K++
Sbjct: 1356 MEAKQNLERHISTLNIQLSDSKKK 1379



 Score = 30.8 bits (68), Expect = 1.4
 Identities = 31/198 (15%), Positives = 75/198 (37%), Gaps = 24/198 (12%)

Query: 36   VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAI 95
            +E + + + K TQ  E++    +   S        +++LE  NKE       +R+KL  +
Sbjct: 1752 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE-------LRSKLHEM 1804

Query: 96   EQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEIT 155
            E +          +++ +I + +  V      +   E   A    +++ K   +  L++ 
Sbjct: 1805 EGAVKSKFKSTIAALEAKIAQLEEQV-----EQEAREKQAATKSLKQKDKKLKEILLQVE 1859

Query: 156  GRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMF 215
                  ++ +E  E G   +            +Q   ++E   ++  ++  + R+L    
Sbjct: 1860 DERKMAEQYKEQAEKGNARV------------KQLKRQLEEAEEESQRINANRRKLQREL 1907

Query: 216  MDMAMFVETQGEMINNIE 233
             +     E  G  +N ++
Sbjct: 1908 DEATESNEAMGREVNALK 1925



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 38/250 (15%), Positives = 102/250 (40%), Gaps = 29/250 (11%)

Query: 25   KDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKT 84
            K+    +    V ++ N    ++   ++ +K   ++    N   K  +E +    E ++ 
Sbjct: 1422 KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1481

Query: 85   ANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERS 144
              K  +  +A+E++ +  E   RT          + +L  +  + ++  ++      E  
Sbjct: 1482 ETKALSLARALEEALEAKEELERT----------NKMLKAEMEDLVSSKDDVGKNVHELE 1531

Query: 145  KGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQAL-----NEIESRHK 199
            K +   + ++    T  +ELE+ L++      T D     ++  QAL      ++++R +
Sbjct: 1532 KSKRALETQMEEMKTQLEELEDELQA------TEDAKLRLEVNMQALKGQFERDLQARDE 1585

Query: 200  DIMKLETSI-RELHEMFMDM-------AMFVETQGEMINNIERNVMNATDYVEHAKEETK 251
               +    + R+LHE   ++       A+    + ++  +++   + A   ++  +E  K
Sbjct: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645

Query: 252  KAIKYQSKAR 261
            +  K Q++ +
Sbjct: 1646 QLRKLQAQMK 1655


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 66/283 (23%), Positives = 122/283 (43%), Gaps = 48/283 (16%)

Query: 3    DRLPDLTACRKNDDGDTVVVVEKDHFMD---------------DFFHQVEEIRNSIDKIT 47
            D+L       + D  D  V++EK H M+               D   +  E++N  +K+ 
Sbjct: 1018 DKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKL- 1076

Query: 48   QYVEEVKKNHSIILSAPNPEGKIK---EELEDLNKEIKKTANKIRAKLKAIEQSFDQDES 104
              VEE  K  S IL+  N   K     E++E L K +  T   ++ +LK++++ +++++ 
Sbjct: 1077 --VEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQ 1134

Query: 105  GNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDEL 164
                   L   +   SV        +AE+ + +  F E+  G I+  L        ++E 
Sbjct: 1135 TVTKLHQLLENQKNSSV-------PLAEHLQIKEAF-EKEVGIIKASLR-----EKEEES 1181

Query: 165  EEMLESGKPSIFTSDIISDSQITRQALNEIESRH-KDIMK-------LETSIRELHEMFM 216
            +  +E        S + S+ Q T+QAL ++E+R   D+ K       LET I  L+E   
Sbjct: 1182 QNKMEE------VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLA 1235

Query: 217  DMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSK 259
            ++    E   E + + ++  ++A D  E      ++ IK Q +
Sbjct: 1236 NLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKE 1278



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 48/235 (20%), Positives = 93/235 (39%), Gaps = 38/235 (16%)

Query: 51   EEVKKNHSIILSAPNPEG-KIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQ-------- 101
            EEVK   +  L+  N E   +K++ ED+N+E  K  +K     + +E + +Q        
Sbjct: 853  EEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISL 912

Query: 102  -DESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQ----TLFRE-----RSKGRIQRQ 151
             +     +S+   +R+ Q S       E +A Y + Q    TL  E     +    IQ  
Sbjct: 913  AEHEAKMSSLSQSMRKVQDS-----NAEILANYRKGQEEIVTLHAEIKAQKKELDTIQEC 967

Query: 152  LEITGR------------TTTDDELEEML--ESGKPSIFTSDIISDSQITRQALNEIESR 197
            +++                 T+ EL++ L  ++ K S+   ++  + Q   +   EI + 
Sbjct: 968  IKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTL 1027

Query: 198  HKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKK 252
             KD+      I + HEM   ++   +   + + ++ +      +  E   EE  K
Sbjct: 1028 QKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK 1082



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 20/109 (18%)

Query: 37   EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE 96
            +++     K +   EEVKKN              K+E + L KEI      +R K   IE
Sbjct: 994  DQLSEQTQKYSVSEEEVKKN--------------KQENDKLKKEIFTLQKDLRDKTVLIE 1039

Query: 97   QSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSK 145
            +S + + + +R + +L     Q   LS+K+ E     N  + L  E +K
Sbjct: 1040 KSHEMERALSRKTDEL---NKQLKDLSQKYTEVK---NVKEKLVEENAK 1082


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 66/283 (23%), Positives = 122/283 (43%), Gaps = 48/283 (16%)

Query: 3    DRLPDLTACRKNDDGDTVVVVEKDHFMD---------------DFFHQVEEIRNSIDKIT 47
            D+L       + D  D  V++EK H M+               D   +  E++N  +K+ 
Sbjct: 1031 DKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKL- 1089

Query: 48   QYVEEVKKNHSIILSAPNPEGKIK---EELEDLNKEIKKTANKIRAKLKAIEQSFDQDES 104
              VEE  K  S IL+  N   K     E++E L K +  T   ++ +LK++++ +++++ 
Sbjct: 1090 --VEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQ 1147

Query: 105  GNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDEL 164
                   L   +   SV        +AE+ + +  F E+  G I+  L        ++E 
Sbjct: 1148 TVTKLHQLLENQKNSSV-------PLAEHLQIKEAF-EKEVGIIKASLR-----EKEEES 1194

Query: 165  EEMLESGKPSIFTSDIISDSQITRQALNEIESRH-KDIMK-------LETSIRELHEMFM 216
            +  +E        S + S+ Q T+QAL ++E+R   D+ K       LET I  L+E   
Sbjct: 1195 QNKMEE------VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLA 1248

Query: 217  DMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSK 259
            ++    E   E + + ++  ++A D  E      ++ IK Q +
Sbjct: 1249 NLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKE 1291



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 48/235 (20%), Positives = 93/235 (39%), Gaps = 38/235 (16%)

Query: 51   EEVKKNHSIILSAPNPEG-KIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQ-------- 101
            EEVK   +  L+  N E   +K++ ED+N+E  K  +K     + +E + +Q        
Sbjct: 866  EEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISL 925

Query: 102  -DESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQ----TLFRE-----RSKGRIQRQ 151
             +     +S+   +R+ Q S       E +A Y + Q    TL  E     +    IQ  
Sbjct: 926  AEHEAKMSSLSQSMRKVQDS-----NAEILANYRKGQEEIVTLHAEIKAQKKELDTIQEC 980

Query: 152  LEITGR------------TTTDDELEEML--ESGKPSIFTSDIISDSQITRQALNEIESR 197
            +++                 T+ EL++ L  ++ K S+   ++  + Q   +   EI + 
Sbjct: 981  IKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTL 1040

Query: 198  HKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKK 252
             KD+      I + HEM   ++   +   + + ++ +      +  E   EE  K
Sbjct: 1041 QKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK 1095



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 20/109 (18%)

Query: 37   EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE 96
            +++     K +   EEVKKN              K+E + L KEI      +R K   IE
Sbjct: 1007 DQLSEQTQKYSVSEEEVKKN--------------KQENDKLKKEIFTLQKDLRDKTVLIE 1052

Query: 97   QSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSK 145
            +S + + + +R + +L     Q   LS+K+ E     N  + L  E +K
Sbjct: 1053 KSHEMERALSRKTDEL---NKQLKDLSQKYTEVK---NVKEKLVEENAK 1095


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 48/270 (17%), Positives = 113/270 (41%), Gaps = 35/270 (12%)

Query: 23  VEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNK--- 79
           ++  H  D+FFH+ E++   I+++       K+    ++       K+K EL  LNK   
Sbjct: 367 MDAQHIKDEFFHEREDLEFKINELLL----AKEEQGCVIE------KLKSELAGLNKQFC 416

Query: 80  --------EIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIR--RTQHSVLSRKFVEA 129
                   E++    + + ++  + ++F  D    + ++   I+  + Q   L ++  EA
Sbjct: 417 YTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEA 476

Query: 130 MAEYNEAQTLFR------ERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISD 183
           +  Y   + +          S G+I ++ E   +    D + E+ +  + +    D + +
Sbjct: 477 ILNYESLREIMEILQTELGESAGKISQEFESMKQQQASD-VHELQQKLRTAFTEKDALLE 535

Query: 184 SQITRQALNE-IESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT-- 240
           +    Q  NE + S+ + + +LE +I+ L E      + +  +  M+  +E  + + T  
Sbjct: 536 TVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEE 595

Query: 241 --DYVEHAKEETKKAIKYQSKARRKLMFII 268
             D++   K   ++   +  K  R+   I+
Sbjct: 596 KDDFINKLKNSHEEMDNFHKKCEREERLIL 625


>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
           b [Homo sapiens]
          Length = 882

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 49/249 (19%), Positives = 113/249 (45%), Gaps = 27/249 (10%)

Query: 24  EKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKK 83
           EKD  + +   ++ +++NS+ K  + +E+ +        A   E  +KE  +D +KE + 
Sbjct: 260 EKDEMLQELEKKLTQVQNSLLKKEKELEKQQ------CMATELEMTVKEAKQDKSKEAEC 313

Query: 84  TANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRER 143
            A  ++A+++ ++ S ++ +   R +     +  + + L+   +E      +   L  ++
Sbjct: 314 KA--LQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQ 371

Query: 144 SKGRIQ---RQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKD 200
               IQ   R+L++  + ++  E E+     +    + ++        +AL ++E+  K+
Sbjct: 372 KADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLEL-------SEALRKLENSDKE 424

Query: 201 IMKLETSIRELHEMFMDMAMFVE----TQGEMINNIERNVMNATDYVEHAKEETKKAIKY 256
             +L+ ++ E      DM   ++     QG +   +E ++  AT  +E  +E+ KK    
Sbjct: 425 KRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKK---- 480

Query: 257 QSKARRKLM 265
            SK   KLM
Sbjct: 481 -SKEHEKLM 488


>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
           a [Homo sapiens]
          Length = 1007

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 49/249 (19%), Positives = 113/249 (45%), Gaps = 27/249 (10%)

Query: 24  EKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKK 83
           EKD  + +   ++ +++NS+ K  + +E+ +        A   E  +KE  +D +KE + 
Sbjct: 405 EKDEMLQELEKKLTQVQNSLLKKEKELEKQQ------CMATELEMTVKEAKQDKSKEAEC 458

Query: 84  TANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRER 143
            A  ++A+++ ++ S ++ +   R +     +  + + L+   +E      +   L  ++
Sbjct: 459 KA--LQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQ 516

Query: 144 SKGRIQ---RQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKD 200
               IQ   R+L++  + ++  E E+     +    + ++        +AL ++E+  K+
Sbjct: 517 KADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLEL-------SEALRKLENSDKE 569

Query: 201 IMKLETSIRELHEMFMDMAMFVE----TQGEMINNIERNVMNATDYVEHAKEETKKAIKY 256
             +L+ ++ E      DM   ++     QG +   +E ++  AT  +E  +E+ KK    
Sbjct: 570 KRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKK---- 625

Query: 257 QSKARRKLM 265
            SK   KLM
Sbjct: 626 -SKEHEKLM 633


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 49/255 (19%), Positives = 119/255 (46%), Gaps = 40/255 (15%)

Query: 34   HQVEEIRNSIDKITQYVEEVKKNHSIILSAPNP-EGKIKEELEDLNKE-------IKKTA 85
            ++++E+     +I +  E + +    + +   P E ++ +E E L KE        +K  
Sbjct: 1957 NRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVR 2016

Query: 86   NKIRAKLKAIEQSFDQD-----ESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLF 140
            + ++ ++KA+E   ++      E     + +L   R Q+  L ++ +E M ++ + Q + 
Sbjct: 2017 DDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQ-LEKMRKFLDEQAID 2075

Query: 141  RERSKG-------RIQRQLEITGR--TTTDDELEEMLESGKPSIFTSDIISDSQITRQAL 191
            RE  +        ++++QL++  R    ++ +  E+ +        +D  S+  ++++ L
Sbjct: 2076 REHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQL 2135

Query: 192  N-EIESRHKDIMKLETSIRELHEMFM--------------DMAMFVETQGE--MINNIER 234
              +I+ R+++I KLE  +REL +  +              ++++ V+ Q E   I+  E+
Sbjct: 2136 QRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEK 2195

Query: 235  NVMNATDYVEHAKEE 249
             + N  + +E  +EE
Sbjct: 2196 EITNLEEQLEQFREE 2210



 Score = 32.3 bits (72), Expect = 0.49
 Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 18/157 (11%)

Query: 69   KIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVD------LRIRRT----- 117
            + +EELE+ N+E+++   ++  + K       + E  N+   D      L I+ +     
Sbjct: 2206 QFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMST 2265

Query: 118  --QHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSI 175
              QH VL  KF + + E  E +         ++Q+QL+IT      +E  E++   +  I
Sbjct: 2266 QDQH-VLFGKFAQIIQE-KEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQI 2323

Query: 176  FTSDIISDSQ-ITRQALNEIESRHKDIMKLETSIREL 211
                ++SD + + R    EIE  ++ I KL+  +  +
Sbjct: 2324 --ECLMSDQECVKRNREEEIEQLNEVIEKLQQELANI 2358


>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
          Length = 1213

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 49/227 (21%), Positives = 96/227 (42%), Gaps = 38/227 (16%)

Query: 72  EELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSV----DLRIRRTQHSVLSRKFV 127
           EELE+ NK ++K   +    L+ +     + E GN + +    +LR R  +      +  
Sbjct: 343 EELEETNKNLQKAEEE----LQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEIT 398

Query: 128 EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLES---------------GK 172
           +  ++  E +   +E      + +LE+        ELE++ E+                K
Sbjct: 399 KTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEK 458

Query: 173 PSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIR-ELHEMFMDMAMFVETQGEMINN 231
               T D++++ ++ +  + E+E     + K E S++ +L ++     M V+ +  M+  
Sbjct: 459 EKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEK 518

Query: 232 I---ERNV--MNATDYVEHAK---------EETKKAIKYQSKARRKL 264
           I   ER V  +N    VE  K         EE+KK +K +S+   K+
Sbjct: 519 IKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKV 565



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 44/218 (20%), Positives = 96/218 (44%), Gaps = 13/218 (5%)

Query: 13  KNDDGDTVVVVEKDHFM----DDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEG 68
           K+DD   ++  E++        +  +Q  + + +  ++ +  +E+ K  S  L   +   
Sbjct: 196 KSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQ 255

Query: 69  KIKEELEDLNKEIKKTANKIRA---KLKAIEQSFDQDESGN-RTSVDLRIRRTQHSVLSR 124
              E+L   +++++    K+R    KLKAI     +D     +  VD   + ++ S    
Sbjct: 256 MHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHE 315

Query: 125 KFVEAMAEYNEAQTLFRERSKGRIQR--QLEITGRTT--TDDELEEMLES-GKPSIFTSD 179
           +    +A         R +  G  QR  +LE T +     ++EL+E+ +   K     S 
Sbjct: 316 EMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSS 375

Query: 180 IISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMD 217
           ++++ +  R+ + E+E + ++I K E+  REL +   +
Sbjct: 376 LMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQE 413


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 57/242 (23%), Positives = 108/242 (44%), Gaps = 29/242 (11%)

Query: 35  QVEEIRNSIDKITQYV-EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANK----IR 89
           Q EE+R   +K  +   EE++K  S          K+K E+++  K I+KT+ +    ++
Sbjct: 397 QGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQ 456

Query: 90  AKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQ 149
            +L  ++Q        +      ++++     L+RK  E   +    +  F+E+ K  ++
Sbjct: 457 QELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALE 516

Query: 150 RQ----LEITGRTTTDDELE-EMLESGKPSIFTS------DIISDSQITRQALNEIESRH 198
           +     L+I+      + L  E LE  K +I T       D+  +++  R  + E+ES  
Sbjct: 517 KSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELES-- 574

Query: 199 KDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQS 258
                LE S++E      D+A+ +E +    +N E  VM     VE  K E  +++K+Q 
Sbjct: 575 ----SLEKSLQENKNQSKDLAVHLEAEKNK-HNKEITVM-----VEKHKTEL-ESLKHQQ 623

Query: 259 KA 260
            A
Sbjct: 624 DA 625



 Score = 35.4 bits (80), Expect = 0.058
 Identities = 40/191 (20%), Positives = 84/191 (43%), Gaps = 17/191 (8%)

Query: 24  EKDHFMDD----FFHQVEEIRN-SIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLN 78
           EK+  + D    F   +EE+   +++K+     E++   S +        K++EEL  L 
Sbjct: 652 EKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLK 711

Query: 79  KEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMA-EYNEAQ 137
            +  K   ++ AK+       D+ ++ ++  VD  I+  +H V  ++  +A+  + N+ +
Sbjct: 712 DQTDKMKQELEAKM-------DEQKNHHQQQVDSIIK--EHEVSIQRTEKALKDQINQLE 762

Query: 138 TLFRERSKGRIQRQLEITGRTTTDDELEEMLE--SGKPSIFTSDIISDSQITRQALNEIE 195
            L +ER K   + Q  +          E  L+  S K  +F S   +  + T+    ++ 
Sbjct: 763 LLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 822

Query: 196 SRHKDIMKLET 206
              + ++ LET
Sbjct: 823 QLQQKLLDLET 833



 Score = 32.7 bits (73), Expect = 0.38
 Identities = 52/301 (17%), Positives = 123/301 (40%), Gaps = 56/301 (18%)

Query: 12   RKNDDGDTVVVVEKDHFMDDFFHQVEE-----IRNSIDKITQYVEEVKK-NHSIILSAPN 65
            R+    +  ++ +K    +D  H + E      +N   K+ +  ++ K+   ++     +
Sbjct: 917  REGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLD 976

Query: 66   PEGKIKEELEDLNKEIKKTANKIRAKLKAIEQS-----------FDQDESGNRTSVDLRI 114
             E K+K+ELE+   E+ +   +  AK+  + Q+            + ++     S+    
Sbjct: 977  QEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVH 1036

Query: 115  RRTQHSVLS------RKFVEAMAEYNEAQTLFRERSKGRIQRQLEITG------------ 156
            RR  + V+S       +  E + E +E Q   +E+    +++++ + G            
Sbjct: 1037 RRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITW 1096

Query: 157  -------RTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIR 209
                   + TT +EL+E L+  + S   + +  D    +  L ++E      + L  S++
Sbjct: 1097 LKEEGVKQDTTLNELQEQLK--QKSAHVNSLAQDETKLKAHLEKLE------VDLNKSLK 1148

Query: 210  E---LHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAK---EETKKAIKYQSKARRK 263
            E   L E  +++ M  E     ++ +   +    +  +  K   E++ K+++ +S   +K
Sbjct: 1149 ENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKK 1208

Query: 264  L 264
            L
Sbjct: 1209 L 1209



 Score = 31.6 bits (70), Expect = 0.84
 Identities = 45/243 (18%), Positives = 107/243 (44%), Gaps = 21/243 (8%)

Query: 21   VVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKN-HSIILSAPNPEGK------IKEE 73
            +V EK+    +  +Q +        ITQ  +E+ +N +++ L     + K      + ++
Sbjct: 1316 LVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQ 1375

Query: 74   LEDLNKEIKK--TANKIRAKLKAIEQSFDQDESGNRTSV-DLRIRRTQHSVLSRKFVEAM 130
            L DLN +++   + ++  A + ++ + +D+++      V DL  +      LS++ + A+
Sbjct: 1376 LTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFK---VDTLSKEKISAL 1432

Query: 131  AEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQA 190
             + ++    F E  K   + Q   T    T  EL+  LE      +  D      + ++ 
Sbjct: 1433 EQVDDWSNKFSEWKK---KAQSRFTQHQNTVKELQIQLELKSKEAYEKD--EQINLLKEE 1487

Query: 191  LNEIESRHKDIMK--LETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKE 248
            L++ +++  D +K  +E    ++ +   ++   +++Q   I  +E ++   T  +E   E
Sbjct: 1488 LDQ-QNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNE 1546

Query: 249  ETK 251
              K
Sbjct: 1547 VLK 1549



 Score = 28.9 bits (63), Expect = 5.4
 Identities = 30/144 (20%), Positives = 66/144 (45%), Gaps = 2/144 (1%)

Query: 53   VKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDL 112
            VK+    IL+  N    +K ELE   KE++     +++K + ++   D+ ES +   +  
Sbjct: 1580 VKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAE 1639

Query: 113  RIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRI-QRQLEITGRTTTDDELEEMLESG 171
              R+ +  + + K  + +++  E +  +++ ++  + +   ++  R      LEE L+S 
Sbjct: 1640 LKRKAEQKIAAIK-KQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSV 1698

Query: 172  KPSIFTSDIISDSQITRQALNEIE 195
            + S   + I+  S     A  E E
Sbjct: 1699 ESSQSETLIVPRSAKNVAAYTEQE 1722


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
           (with transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 42/215 (19%), Positives = 100/215 (46%), Gaps = 22/215 (10%)

Query: 33  FHQVEEI--------RNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKT 84
           FH+ +EI           I  + Q +EE KKN     SA      + EE + L  ++K+ 
Sbjct: 700 FHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFT---ALSEERDQLLSQVKEL 756

Query: 85  A--NKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRE 142
           +   ++RA++K +E +  + E   R   +    +T H  L  + + +++   +++ +  E
Sbjct: 757 SMVTELRAQVKQLEMNLAEAERQRRLDYE---SQTAHDNLLTEQIHSLSIEAKSKDVKIE 813

Query: 143 RSKGRIQR-QLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDI 201
             +  +   QL+ + ++T    L+  L++ +     S+++  ++  R   +++E   + +
Sbjct: 814 VLQNELDDVQLQFSEQSTLIRSLQSQLQNKE-----SEVLEGAERVRHISSKVEELSQAL 868

Query: 202 MKLETSIRELHEMFMDMAMFVETQGEMINNIERNV 236
            + E  I ++ ++ ++    VET  + I   ++ V
Sbjct: 869 SQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV 903



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 66/271 (24%), Positives = 116/271 (42%), Gaps = 53/271 (19%)

Query: 18   DTVVVVEKDHF-----MDDFFHQVEEIRNSIDKITQYVEEVKKNH-SIIL-------SAP 64
            +T+  ++K++      +D F   +  ++N  D+I    +++++ H SIIL        A 
Sbjct: 2443 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAA 2502

Query: 65   NPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVD------LRIRRTQ 118
                K+KEE+  L   +    N   AKL A    + +D +   T  D      L ++  Q
Sbjct: 2503 AENNKLKEEIRGLRSHM-DDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQ 2561

Query: 119  HSVLSRKFV---EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSI 175
            +  L  K+    E + E  EA    R RS   +Q + +         +L + +ES K SI
Sbjct: 2562 NKELENKYAKLEEKLKESEEANEDLR-RSFNALQEEKQ---------DLSKEIESLKVSI 2611

Query: 176  FTSDIISDSQITRQ--ALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIE 233
                    SQ+TRQ  AL E  +      +L+    E+H +    A+F  +Q + I  +E
Sbjct: 2612 --------SQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRL---SALFSSSQ-KRIAELE 2659

Query: 234  RNVMNATDYVEHAKEETKKAIKYQSKARRKL 264
              ++         KE  KK  + + K +++L
Sbjct: 2660 EELVCV------QKEAAKKVGEIEDKLKKEL 2684



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 43/251 (17%), Positives = 106/251 (42%), Gaps = 23/251 (9%)

Query: 29   MDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKI 88
            ++++  Q+++++   ++I    EE +KN     +  N +  +  ++   + E+K    ++
Sbjct: 1835 INNYLQQIDQLK---ERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEV 1891

Query: 89   RAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYN-EAQTLFRERSKGR 147
              K+  + Q   ++ S  R +        +   L  + +  +AE N       ++ +  +
Sbjct: 1892 -TKMNLLNQQIQEELS--RVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQ 1948

Query: 148  IQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKD------I 201
            I+ +L +        +    LE  K  +       +S+I ++ L +I+   K+       
Sbjct: 1949 IKNEL-LESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHA 2007

Query: 202  MKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYV--------EHAKEETKKA 253
             +L+  ++E  +    +        E I+ +ER V  A ++V        E  KE   +A
Sbjct: 2008 KELQELLKEKQQEVKQLQKDCIRYQEKISALERTV-KALEFVQTESQKDLEITKENLAQA 2066

Query: 254  IKYQSKARRKL 264
            ++++ KA+ +L
Sbjct: 2067 VEHRKKAQAEL 2077



 Score = 30.8 bits (68), Expect = 1.4
 Identities = 48/275 (17%), Positives = 100/275 (36%), Gaps = 52/275 (18%)

Query: 31   DFFHQVEEIRNSIDKITQYV--------------------EEVKKNHSIILSAPNPEGKI 70
            D   ++E ++ SI ++T+ V                    EEV +  ++  S+     ++
Sbjct: 2599 DLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAEL 2658

Query: 71   KEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAM 130
            +EEL  + KE  K   +I  KLK   +    D    R   +    R   + L+R  VE  
Sbjct: 2659 EEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERV--AELARDLVEM- 2715

Query: 131  AEYNEAQTLFRERSKGRIQRQLEITGRTTTD-----------------------DELEEM 167
                E + L   +    +  Q++  GR+ +                         EL ++
Sbjct: 2716 ----EQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQL 2771

Query: 168  LESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGE 227
             E G  +     ++S++  +  +  E    H  + KL   +    E  + ++  +E    
Sbjct: 2772 KEQGLLNRERDALLSETAFSMNSTEENSLSH--LEKLNQQLLSKDEQLLHLSSQLEDSYN 2829

Query: 228  MINNIERNVMNATDYVEHAKEETKKAIKYQSKARR 262
             + +  + + +  +  +H   E +K  K +   +R
Sbjct: 2830 QVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQR 2864


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 56/261 (21%), Positives = 114/261 (43%), Gaps = 32/261 (12%)

Query: 29   MDDFFHQVEEIRNSIDKI-TQYVEEVKKNHSI----------ILSAPNPEGKIKEELEDL 77
            M D+  ++EE R S D+I  Q  E  KK  S+          + S+       ++E ++L
Sbjct: 1654 MKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDEL 1713

Query: 78   NKEIKKTAN----------KIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFV 127
              EI  +A+          ++ A++  +E+  ++++S N   ++ R R+T   V +    
Sbjct: 1714 ADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQS-NMELLNDRFRKTTLQVDTLN-A 1771

Query: 128  EAMAEYNEAQTLFRERSKGRIQRQ-LEITGRTTTDDELEEMLESGKPSIFTSDIISDSQI 186
            E  AE + AQ    + ++ +++RQ  E+  +     ELE  ++S   +  ++      Q+
Sbjct: 1772 ELAAERSAAQK--SDNARQQLERQNKELKAKL---QELEGAVKSKFKATISALEAKIGQL 1826

Query: 187  TRQALNEIESR---HKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYV 243
              Q   E + R   +K + + E  ++E+     D     +   E +      +      +
Sbjct: 1827 EEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQL 1886

Query: 244  EHAKEETKKAIKYQSKARRKL 264
            E A+EE  +A   + K +R+L
Sbjct: 1887 EEAEEEATRANASRRKLQREL 1907



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 56/278 (20%), Positives = 116/278 (41%), Gaps = 43/278 (15%)

Query: 7    DLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYV---------EEVKKNH 57
            +L   ++  DG+T  + ++   + +   Q++E++  + K  + +         E + KN+
Sbjct: 1052 ELEKAKRKLDGETTDLQDQ---IAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNN 1108

Query: 58   SIILSAPNPEGKIKEELEDLNKEIKKTANK-------IRAKLKAIEQSFDQDESGNRTSV 110
            ++ +     + +I E  ED   E K + NK       +  +L+A++   +          
Sbjct: 1109 ALKV-VRELQAQIAELQEDFESE-KASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166

Query: 111  DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEM--- 167
            +LR +R Q     +K +E   + +EAQ         +  RQ   T      ++LE+    
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQI--------QDMRQRHATALEELSEQLEQAKRF 1218

Query: 168  ---LESGKPSIFT--SDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFV 222
               LE  K  + T   ++  + ++ +Q   E E + K   KL+  ++ELH    +     
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRK---KLDAQVQELHAKVSEGDRLR 1275

Query: 223  ETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKA 260
                E  + ++  + N +  +E A+   KK IK+   A
Sbjct: 1276 VELAEKASKLQNELDNVSTLLEEAE---KKGIKFAKDA 1310



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 54/234 (23%), Positives = 108/234 (46%), Gaps = 22/234 (9%)

Query: 43   IDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQD 102
            + ++ + +EE  KNH   +   +   +    LE+L++++++ A + +A L+  +Q  + D
Sbjct: 1176 VAELKKALEEETKNHEAQIQ--DMRQRHATALEELSEQLEQ-AKRFKANLEKNKQGLETD 1232

Query: 103  ESGNRTSVDLRIRRTQHSVLSRKFVEAM-----AEYNEAQTLFRERSKGRIQRQLEITGR 157
                   V +  +    S   RK ++A      A+ +E   L  E ++   + Q E+   
Sbjct: 1233 NKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNV 1292

Query: 158  TTTDDELEEMLESGKPSIFTSDIIS-DSQI--TRQALNEIESRHKDIMKLETSIRELHEM 214
            +T  +E E+     K   F  D  S +SQ+  T++ L E E+R K  + L + IR+L E 
Sbjct: 1293 STLLEEAEK-----KGIKFAKDAASLESQLQDTQELLQE-ETRQK--LNLSSRIRQLEEE 1344

Query: 215  FMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKK---AIKYQSKARRKLM 265
               +    E + E   N+E+ V+     +   K++       I+   +A++KL+
Sbjct: 1345 KNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLL 1398



 Score = 37.4 bits (85), Expect = 0.015
 Identities = 55/246 (22%), Positives = 107/246 (43%), Gaps = 33/246 (13%)

Query: 35   QVEEIRNSIDKITQYVEEVKKN---HSIILSAPNPEGKIK--------EELEDLNKEIKK 83
            Q+EE +NS+ +  +  EE +KN     + L +   + K K        E LE+  K++ K
Sbjct: 1340 QLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLK 1399

Query: 84   TANKIRAKLKAIEQSFDQ-DESGNR-------TSVDLRIRRTQHSVL---SRKFVEAMAE 132
             A  +  +L+    ++D+ +++ NR        +VDL  +R   S L    +KF + +AE
Sbjct: 1400 DAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAE 1459

Query: 133  YNEAQTLF-RERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQAL 191
                   +  ER +   + + + T   +    LEE LE+        +    ++  R  +
Sbjct: 1460 EKSISARYAEERDRAEAEAREKETKALSLARALEEALEA------KEEFERQNKQLRADM 1513

Query: 192  NEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETK 251
             ++ S   D+ K   ++ EL +    +   VE     +  +E + + AT+  +   E   
Sbjct: 1514 EDLMSSKDDVGK---NVHELEKSKRALEQQVEEMRTQLEELE-DELQATEDAKLRLEVNM 1569

Query: 252  KAIKYQ 257
            +A+K Q
Sbjct: 1570 QAMKAQ 1575



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 44/228 (19%), Positives = 98/228 (42%), Gaps = 21/228 (9%)

Query: 45   KITQYVEEVKKNHSIILSAPNPEGKIKEELEDL---NKEIKKTANKIRAKLKAIEQSFDQ 101
            ++T+  EE++     +L     + K++ ELE++   ++++ +  N +  +L+A  + F +
Sbjct: 846  QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905

Query: 102  DES--GNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQ---RQLEITG 156
             E       +    +    H + SR  VE   E N+     +++ +  IQ    QL+   
Sbjct: 906  AEEMRARLAAKKQELEEILHDLESR--VEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE 963

Query: 157  RTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFM 216
                  +LE++    K      +I+       + + E +     I +  + + E  E   
Sbjct: 964  GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAK 1023

Query: 217  DMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKL 264
            ++A     Q  MI+++E  +          +E+T++ ++   KA+RKL
Sbjct: 1024 NLAKIRNKQEVMISDLEERLKK--------EEKTRQELE---KAKRKL 1060



 Score = 32.0 bits (71), Expect = 0.64
 Identities = 31/152 (20%), Positives = 64/152 (42%), Gaps = 22/152 (14%)

Query: 22   VVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEI 81
            + + +  +++    +E + +   K T  V+ +    +   SA       +++LE  NKE+
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKEL 1797

Query: 82   ---------------KKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKF 126
                           K T + + AK+  +E+  +Q E+  R + +  +RRT+   L   F
Sbjct: 1798 KAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ-EAKERAAANKLVRRTEKK-LKEIF 1855

Query: 127  VEAMAEYNEAQTLFRERSKG-----RIQRQLE 153
            ++   E   A     +  K      +++RQLE
Sbjct: 1856 MQVEDERRHADQYKEQMEKANARMKQLKRQLE 1887



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 35/191 (18%), Positives = 85/191 (44%), Gaps = 21/191 (10%)

Query: 36   VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAI 95
            +EE   + ++  +  ++++ +   ++S+ +  GK   ELE   + +++   ++R +L+ +
Sbjct: 1492 LEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEEL 1551

Query: 96   EQSFDQDESGN-RTSVDLRIRRTQHSVLSRKFVEAMAEYNE---------AQTLFRERSK 145
            E      E    R  V+++  + Q      + ++   E NE          + L  E   
Sbjct: 1552 EDELQATEDAKLRLEVNMQAMKAQF----ERDLQTRDEQNEEKKRLLIKQVRELEAELED 1607

Query: 146  GRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMK-L 204
             R QR L +  +   + +L+++    +  I  ++   D  I  + L +++++ KD  + L
Sbjct: 1608 ERKQRALAVASKKKMEIDLKDL----EAQIEAANKARDEVI--KQLRKLQAQMKDYQREL 1661

Query: 205  ETSIRELHEMF 215
            E +     E+F
Sbjct: 1662 EEARASRDEIF 1672


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,908,935
Number of Sequences: 37866
Number of extensions: 352388
Number of successful extensions: 2939
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 318
Number of HSP's that attempted gapping in prelim test: 2343
Number of HSP's gapped (non-prelim): 845
length of query: 287
length of database: 18,247,518
effective HSP length: 101
effective length of query: 186
effective length of database: 14,423,052
effective search space: 2682687672
effective search space used: 2682687672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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