Guide to the Human Genome
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Search of human proteins with 36951034

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|36951034 G protein-coupled receptor 78 [Homo sapiens]
         (363 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|36951034 G protein-coupled receptor 78 [Homo sapiens]              720   0.0  
gi|23592220 G protein-coupled receptor 26 [Homo sapiens]              330   2e-90
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi...    87   3e-17
gi|149944554 somatostatin receptor 4 [Homo sapiens]                    84   2e-16
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]          81   2e-15
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]          81   2e-15
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]          81   2e-15
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]          81   2e-15
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]          81   2e-15
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]          81   2e-15
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]         80   2e-15
gi|4557857 somatostatin receptor 1 [Homo sapiens]                      80   3e-15
gi|4503391 dopamine receptor D5 [Homo sapiens]                         80   4e-15
gi|4557865 somatostatin receptor 5 [Homo sapiens]                      79   6e-15
gi|4557859 somatostatin receptor 2 [Homo sapiens]                      77   2e-14
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]            77   2e-14
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]             77   2e-14
gi|4503905 galanin receptor 2 [Homo sapiens]                           77   2e-14
gi|222080095 orexin receptor 1 [Homo sapiens]                          77   2e-14
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]                77   3e-14
gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens]             76   5e-14
gi|4503383 dopamine receptor D1 [Homo sapiens]                         74   2e-13
gi|222080109 orexin receptor 2 [Homo sapiens]                          72   6e-13
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]    72   6e-13
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]    72   6e-13
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]     72   6e-13
gi|4557861 somatostatin receptor 3 [Homo sapiens]                      69   5e-12
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                 69   9e-12
gi|223633986 trace amine associated receptor 5 [Homo sapiens]          69   9e-12
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]       68   1e-11

>gi|36951034 G protein-coupled receptor 78 [Homo sapiens]
          Length = 363

 Score =  720 bits (1858), Expect = 0.0
 Identities = 363/363 (100%), Positives = 363/363 (100%)

Query: 1   MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDM 60
           MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDM
Sbjct: 1   MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDM 60

Query: 61  PFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRP 120
           PFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRP
Sbjct: 61  PFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRP 120

Query: 121 RYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVG 180
           RYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVG
Sbjct: 121 RYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVG 180

Query: 181 FVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRAT 240
           FVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRAT
Sbjct: 181 FVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRAT 240

Query: 241 RKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRP 300
           RKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRP
Sbjct: 241 RKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRP 300

Query: 301 FRQVLAGMVHRLLKRTPRPASTHDSSLDVAGMVHQLLKRTPRPASTHNGSVDTENDSCLQ 360
           FRQVLAGMVHRLLKRTPRPASTHDSSLDVAGMVHQLLKRTPRPASTHNGSVDTENDSCLQ
Sbjct: 301 FRQVLAGMVHRLLKRTPRPASTHDSSLDVAGMVHQLLKRTPRPASTHNGSVDTENDSCLQ 360

Query: 361 QTH 363
           QTH
Sbjct: 361 QTH 363


>gi|23592220 G protein-coupled receptor 26 [Homo sapiens]
          Length = 337

 Score =  330 bits (845), Expect = 2e-90
 Identities = 170/327 (51%), Positives = 222/327 (67%), Gaps = 4/327 (1%)

Query: 1   MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDM 60
           M   +A LAGLLV  + V+LLSNALVLLC  +SA++R +A  +  +NL+ G+LL   ++M
Sbjct: 1   MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNM 60

Query: 61  PFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRP 120
           P TL GV+  R P+    C++  FLDTFLA+N+ LS+AALS D+W+AV FPL Y  ++R 
Sbjct: 61  PLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRL 120

Query: 121 RYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVG 180
           R A L++   W  +L F  AAL  SWLG+   +ASC+L      ER RFA FT   HA+ 
Sbjct: 121 RDAALMVAYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALS 180

Query: 181 FVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRAT 240
           F+L   VLC T L+V +VAR HC+R+D +TM+ L LL DLHPSVR+RCL +QKRRR RAT
Sbjct: 181 FLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRAT 240

Query: 241 RKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRP 300
           +KI   I TFL+CFAPYV+TRL EL   V + + WG+LSKCL YSKA +DPF YSLLR  
Sbjct: 241 KKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQ 300

Query: 301 FRQVLAGMVHRLLKRTPRPASTHDSSL 327
           +R+    +++RLL R     S H S L
Sbjct: 301 YRKSCKEILNRLLHR----RSIHSSGL 323


>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
           sapiens]
          Length = 440

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 77/318 (24%), Positives = 136/318 (42%), Gaps = 27/318 (8%)

Query: 4   GEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFT 63
           G   +A  L +V+A+   +N+L++        LR   S   LV+L    L++  + MP  
Sbjct: 25  GSGWVAAALCVVIALTAAANSLLIALICTQPALRN-TSNFFLVSLFTSDLMVGLVVMPPA 83

Query: 64  LLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYA 123
           +L  + GR   A G C +    D    S + L++  +S D++L +  PLRY  R+ P  A
Sbjct: 84  MLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRA 143

Query: 124 GLLLGCAWGQSLAFSGAALGCSW--LGYSSAFASCSLRLPPEPERPRFAA---FTATLHA 178
             L+  AW  +   S   L   W  LG++          PP P + R  A   F      
Sbjct: 144 LALVLGAWSLAALASFLPLLLGWHELGHAR---------PPVPGQCRLLASLPFVLVASG 194

Query: 179 VGFVLPLAVLCLTSLQVHRVARRHCQRMDTVT-------MKALALLADLHPSVR----QR 227
           + F LP   +C T  ++   AR+   ++ ++T        + L +     P V     +R
Sbjct: 195 LTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRR 254

Query: 228 CLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKA 287
              +  R+  +A+  +GI +  F + + P+ +  + + V        + +L+  L Y  +
Sbjct: 255 LATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLT-WLGYCNS 313

Query: 288 VADPFTYSLLRRPFRQVL 305
             +P  Y L  R F++ L
Sbjct: 314 TMNPIIYPLFMRDFKRAL 331


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 82/311 (26%), Positives = 137/311 (44%), Gaps = 37/311 (11%)

Query: 2   GPGEALLAGLLV------MVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLL 55
           GPG+A  AG++       +V  V L+ NALV+      A+++T A+ + L+NL++   L 
Sbjct: 38  GPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKT-ATNIYLLNLAVADELF 96

Query: 56  AALDMPFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYA 115
             L +PF          P     C+ +  +D      +   +  LS D+++AV  PLR A
Sbjct: 97  M-LSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAA 155

Query: 116 GRLRPRYAGLLLGCAWGQSL--AFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFT 173
              RP  A L+    W  SL      A    +         +C+L+ P       F  +T
Sbjct: 156 TYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYT 215

Query: 174 ATLHAVGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQK 233
             L   GF+LP+  + L            C  +    M+A+AL A            Q++
Sbjct: 216 FLL---GFLLPVLAIGL------------CYLLIVGKMRAVALRAGWQ---------QRR 251

Query: 234 RRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFVT-VNAQWGILSKCLTYSKAVADPF 292
           R   + TR + + +  F++C+ P+ + +L  L  FVT ++A    +S  L+Y+ + A+P 
Sbjct: 252 RSEKKITRLVLMVVVVFVLCWMPFYVVQLLNL--FVTSLDATVNHVSLILSYANSCANPI 309

Query: 293 TYSLLRRPFRQ 303
            Y  L   FR+
Sbjct: 310 LYGFLSDNFRR 320


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 67/307 (21%), Positives = 132/307 (42%), Gaps = 12/307 (3%)

Query: 5   EALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTL 64
           + +L   L  V+ +A+L N LV++   +  +LR   +   +V+L+   LL++ L MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 65  LGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGF-PLRYAGRLRPRYA 123
           + +++         C V   LD  L + +   +  +S D++ A+   PL Y  ++ P   
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 124 GLLLGCAW--GQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAA---FTATLHA 178
            L+LG  W     ++F     G + +G                    F     +  T   
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 179 VGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHR 238
           V F +P  ++ L   +++  A+ H  ++    ++     ++  P    +    + R   +
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 239 ATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQWGILSKCLTYSKAVADPFTYSL 296
           A + + I +  F +C+AP+ +T + +  PF+  TV  Q       L Y  +  +PF Y+ 
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTAFLWLGYINSGLNPFLYAF 314

Query: 297 LRRPFRQ 303
           L + FR+
Sbjct: 315 LNKSFRR 321


>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 67/307 (21%), Positives = 132/307 (42%), Gaps = 12/307 (3%)

Query: 5   EALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTL 64
           + +L   L  V+ +A+L N LV++   +  +LR   +   +V+L+   LL++ L MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 65  LGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGF-PLRYAGRLRPRYA 123
           + +++         C V   LD  L + +   +  +S D++ A+   PL Y  ++ P   
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 124 GLLLGCAW--GQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAA---FTATLHA 178
            L+LG  W     ++F     G + +G                    F     +  T   
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 179 VGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHR 238
           V F +P  ++ L   +++  A+ H  ++    ++     ++  P    +    + R   +
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 239 ATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQWGILSKCLTYSKAVADPFTYSL 296
           A + + I +  F +C+AP+ +T + +  PF+  TV  Q       L Y  +  +PF Y+ 
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTAFLWLGYINSGLNPFLYAF 314

Query: 297 LRRPFRQ 303
           L + FR+
Sbjct: 315 LNKSFRR 321


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 67/307 (21%), Positives = 132/307 (42%), Gaps = 12/307 (3%)

Query: 5   EALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTL 64
           + +L   L  V+ +A+L N LV++   +  +LR   +   +V+L+   LL++ L MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 65  LGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGF-PLRYAGRLRPRYA 123
           + +++         C V   LD  L + +   +  +S D++ A+   PL Y  ++ P   
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 124 GLLLGCAW--GQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAA---FTATLHA 178
            L+LG  W     ++F     G + +G                    F     +  T   
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 179 VGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHR 238
           V F +P  ++ L   +++  A+ H  ++    ++     ++  P    +    + R   +
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 239 ATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQWGILSKCLTYSKAVADPFTYSL 296
           A + + I +  F +C+AP+ +T + +  PF+  TV  Q       L Y  +  +PF Y+ 
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTAFLWLGYINSGLNPFLYAF 314

Query: 297 LRRPFRQ 303
           L + FR+
Sbjct: 315 LNKSFRR 321


>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
          Length = 387

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 67/307 (21%), Positives = 132/307 (42%), Gaps = 12/307 (3%)

Query: 5   EALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTL 64
           + +L   L  V+ +A+L N LV++   +  +LR   +   +V+L+   LL++ L MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 65  LGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGF-PLRYAGRLRPRYA 123
           + +++         C V   LD  L + +   +  +S D++ A+   PL Y  ++ P   
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 124 GLLLGCAW--GQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAA---FTATLHA 178
            L+LG  W     ++F     G + +G                    F     +  T   
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 179 VGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHR 238
           V F +P  ++ L   +++  A+ H  ++    ++     ++  P    +    + R   +
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 239 ATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQWGILSKCLTYSKAVADPFTYSL 296
           A + + I +  F +C+AP+ +T + +  PF+  TV  Q       L Y  +  +PF Y+ 
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTAFLWLGYINSGLNPFLYAF 314

Query: 297 LRRPFRQ 303
           L + FR+
Sbjct: 315 LNKSFRR 321


>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
          Length = 378

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 67/307 (21%), Positives = 132/307 (42%), Gaps = 12/307 (3%)

Query: 5   EALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTL 64
           + +L   L  V+ +A+L N LV++   +  +LR   +   +V+L+   LL++ L MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 65  LGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGF-PLRYAGRLRPRYA 123
           + +++         C V   LD  L + +   +  +S D++ A+   PL Y  ++ P   
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 124 GLLLGCAW--GQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAA---FTATLHA 178
            L+LG  W     ++F     G + +G                    F     +  T   
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 179 VGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHR 238
           V F +P  ++ L   +++  A+ H  ++    ++     ++  P    +    + R   +
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 239 ATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQWGILSKCLTYSKAVADPFTYSL 296
           A + + I +  F +C+AP+ +T + +  PF+  TV  Q       L Y  +  +PF Y+ 
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTAFLWLGYINSGLNPFLYAF 314

Query: 297 LRRPFRQ 303
           L + FR+
Sbjct: 315 LNKSFRR 321


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 67/307 (21%), Positives = 132/307 (42%), Gaps = 12/307 (3%)

Query: 5   EALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTL 64
           + +L   L  V+ +A+L N LV++   +  +LR   +   +V+L+   LL++ L MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 65  LGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGF-PLRYAGRLRPRYA 123
           + +++         C V   LD  L + +   +  +S D++ A+   PL Y  ++ P   
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 124 GLLLGCAW--GQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAA---FTATLHA 178
            L+LG  W     ++F     G + +G                    F     +  T   
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 179 VGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHR 238
           V F +P  ++ L   +++  A+ H  ++    ++     ++  P    +    + R   +
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSESRPQSADQHSTHRMRTETK 256

Query: 239 ATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQWGILSKCLTYSKAVADPFTYSL 296
           A + + I +  F +C+AP+ +T + +  PF+  TV  Q       L Y  +  +PF Y+ 
Sbjct: 257 AAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTAFLWLGYINSGLNPFLYAF 314

Query: 297 LRRPFRQ 303
           L + FR+
Sbjct: 315 LNKSFRR 321


>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
          Length = 402

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 69/321 (21%), Positives = 133/321 (41%), Gaps = 26/321 (8%)

Query: 5   EALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTL 64
           + +L   L  V+ +A+L N LV++   +  +LR   +   +V+L+   LL++ L MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 65  LGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGF-PLRYAGRLRPRYA 123
           + +++         C V   LD  L + +   +  +S D++ A+   PL Y  ++ P   
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 124 GLLLGCAWGQSLAFSGAALGCSW-------------LGYSSAFASCSLRLPPEPERPRFA 170
            L+LG  W      S   +   W              G    F +   R   +     + 
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYC 198

Query: 171 AF------TATLHAVGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSV 224
            F        T   V F +P  ++ L   +++  A+ H  ++    ++     ++  P  
Sbjct: 199 VFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQ--MLQRAGASSESRPQS 256

Query: 225 RQRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFV--TVNAQWGILSKCL 282
             +    + R   +A + + I +  F +C+AP+ +T + +  PF+  TV  Q       L
Sbjct: 257 ADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVD--PFIDYTVPGQVWTAFLWL 314

Query: 283 TYSKAVADPFTYSLLRRPFRQ 303
            Y  +  +PF Y+ L + FR+
Sbjct: 315 GYINSGLNPFLYAFLNKSFRR 335


>gi|4557857 somatostatin receptor 1 [Homo sapiens]
          Length = 391

 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 77/316 (24%), Positives = 138/316 (43%), Gaps = 43/316 (13%)

Query: 2   GPGEALLAGLLVMVLA-VALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDM 60
           G G A+L   +  V+  V L  N++V+      A+++T A+ + ++NL++   LL  L +
Sbjct: 54  GQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKT-ATNIYILNLAIADELLM-LSV 111

Query: 61  PFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRP 120
           PF +   +    P     C+++  +D      +   +  LS D+++AV  P++ A   RP
Sbjct: 112 PFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRP 171

Query: 121 RYAGLLLGCAWGQSL-------AFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFT 173
             A ++    W  SL        FS  A        S    +C++ L PEP +     F 
Sbjct: 172 TVAKVVNLGVWVLSLLVILPIVVFSRTAAN------SDGTVACNM-LMPEPAQRWLVGFV 224

Query: 174 ATLHAVGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQK 233
                +GF+LP+  +CL            C  +    M+ +AL A            Q+K
Sbjct: 225 LYTFLMGFLLPVGAICL------------CYVLIIAKMRMVALKAGWQ---------QRK 263

Query: 234 RRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFT 293
           R   + T  + + +  F+IC+ P+ + +L  +      +A    LS  L Y+ + A+P  
Sbjct: 264 RSERKITLMVMMVVMVFVICWMPFYVVQLVNVFA-EQDDATVSQLSVILGYANSCANPIL 322

Query: 294 YSLL----RRPFRQVL 305
           Y  L    +R F+++L
Sbjct: 323 YGFLSDNFKRSFQRIL 338


>gi|4503391 dopamine receptor D5 [Homo sapiens]
          Length = 477

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 69/295 (23%), Positives = 133/295 (45%), Gaps = 36/295 (12%)

Query: 1   MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDM 60
           +GP + + A LL +++   LL N LV      S  LR   + V +V+L++  L +A L M
Sbjct: 36  LGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVM 95

Query: 61  PFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRP 120
           P+  +  + G  P     C V    D   ++ + L++  +S D++ A+  P RY  ++  
Sbjct: 96  PWKAVAEVAGYWPFG-AFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQ 154

Query: 121 RYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPP-------------EPE-- 165
           R A +++G AW  S+  S   +  +W     A +   L LP              EP+  
Sbjct: 155 RMALVMVGLAWTLSILISFIPVQLNW-HRDQAASWGGLDLPNNLANWTPWEEDFWEPDVN 213

Query: 166 -------RPRFAAFTATLHAVGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKA----- 213
                    R  A +++L  + F +P+A++ +T  +++R+A+   +R+ ++   A     
Sbjct: 214 AENCDSSLNRTYAISSSL--ISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQS 271

Query: 214 LALLADLHPSVRQRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPF 268
               A   P    R  I   ++  +  + + + +  F+ C+ P+ +  L  +VPF
Sbjct: 272 CRSSAACAPDTSLRASI---KKETKVLKTLSVIMGVFVCCWLPFFI--LNCMVPF 321


>gi|4557865 somatostatin receptor 5 [Homo sapiens]
          Length = 364

 Score = 79.0 bits (193), Expect = 6e-15
 Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 53/316 (16%)

Query: 2   GPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMP 61
           G    L+  L ++V A  L  N LV+      A+++T  + + ++NL++  +L   L +P
Sbjct: 37  GARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKT-VTNIYILNLAVADVLYM-LGLP 94

Query: 62  FTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPR 121
           F          P  P  C+++  LD      +   +  +S D++LAV  PL  A   RPR
Sbjct: 95  FLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPR 154

Query: 122 YAGLLLGCAWGQSLAFS-----------GAALGCSWLGYSSAFASCSLRLPPEPERPRFA 170
            A L    AW  SL  S           G     SW               PEP     A
Sbjct: 155 VAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASW---------------PEPVGLWGA 199

Query: 171 AFTATLHAVGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLI 230
            F      +GF  PL V+CL            C  +  V ++A          VR  C+ 
Sbjct: 200 VFIIYTAVLGFFAPLLVICL------------CYLLIVVKVRA--------AGVRVGCV- 238

Query: 231 QQKRRRHRATRKIGIAIATFLICFAPYV---MTRLAELVPFVTVNAQWGILSKCLTYSKA 287
            ++R   + TR + + +  F  C+ P+    +  LA  +P    +A        L+Y+ +
Sbjct: 239 -RRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANS 297

Query: 288 VADPFTYSLLRRPFRQ 303
            A+P  Y  L   FRQ
Sbjct: 298 CANPVLYGFLSDNFRQ 313


>gi|4557859 somatostatin receptor 2 [Homo sapiens]
          Length = 369

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 69/307 (22%), Positives = 132/307 (42%), Gaps = 38/307 (12%)

Query: 6   ALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTLL 65
           A+L  +  +V  + L  N LV+      A+++T  + + ++NL++   L   L +PF  +
Sbjct: 44  AVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKT-ITNIYILNLAIADELFM-LGLPFLAM 101

Query: 66  GVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYAGL 125
            V     P     C+V+  +D      +   +  +S D++LAV  P++ A   RPR A +
Sbjct: 102 QVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKM 161

Query: 126 LLGCAWGQSL-----AFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVG 180
           +    WG SL         A L  +  G S    SC++  P E     +  F      +G
Sbjct: 162 ITMAVWGVSLLVILPIMIYAGLRSNQWGRS----SCTINWPGE-SGAWYTGFIIYTFILG 216

Query: 181 FVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRAT 240
           F++PL ++CL            C     + +K+  +              ++K+   + T
Sbjct: 217 FLVPLTIICL------------CYLFIIIKVKSSGIRVGSS---------KRKKSEKKVT 255

Query: 241 RKIGIAIATFLICFAPYVMTRLAE----LVPFVTVNAQWGILSKCLTYSKAVADPFTYSL 296
           R + I +A F+ C+ P+ +  ++     + P   +   +  +   LTY+ + A+P  Y+ 
Sbjct: 256 RMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFV-VVLTYANSCANPILYAF 314

Query: 297 LRRPFRQ 303
           L   F++
Sbjct: 315 LSDNFKK 321


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 65/293 (22%), Positives = 123/293 (41%), Gaps = 21/293 (7%)

Query: 11  LLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTLLGVMRG 70
           +L +++ + +  N +V L    +  LR   +   +V+L++  LLL  L +PF+ +  +  
Sbjct: 24  VLAVLILITVAGNVVVCLAVGLNRRLRN-LTNCFIVSLAITDLLLGLLVLPFSAIYQLSC 82

Query: 71  RTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYAGLLLGCA 130
           +       C +   LD  L + + L++  +S D++ AV  PLRY   + P    + L   
Sbjct: 83  KWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLI 142

Query: 131 WGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVGFVLPLAVLCL 190
           W  S+  S  ++   W   +            + +          L  V F LPL ++C+
Sbjct: 143 WVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGL--VTFYLPLLIMCI 200

Query: 191 TSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRATRKIGIAIATF 250
           T  ++ +VAR   +R++ ++    A +                 R H+AT  +   +  F
Sbjct: 201 TYYRIFKVARDQAKRINHISSWKAATI-----------------REHKATVTLAAVMGAF 243

Query: 251 LICFAPYVMTRLAE-LVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRPFR 302
           +IC+ PY    +   L     +N     +   L Y+ +  +P  Y+ L R FR
Sbjct: 244 IICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFR 296


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 65/293 (22%), Positives = 123/293 (41%), Gaps = 21/293 (7%)

Query: 11  LLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTLLGVMRG 70
           +L +++ + +  N +V L    +  LR   +   +V+L++  LLL  L +PF+ +  +  
Sbjct: 24  VLAVLILITVAGNVVVCLAVGLNRRLRN-LTNCFIVSLAITDLLLGLLVLPFSAIYQLSC 82

Query: 71  RTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYAGLLLGCA 130
           +       C +   LD  L + + L++  +S D++ AV  PLRY   + P    + L   
Sbjct: 83  KWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLI 142

Query: 131 WGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVGFVLPLAVLCL 190
           W  S+  S  ++   W   +            + +          L  V F LPL ++C+
Sbjct: 143 WVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGL--VTFYLPLLIMCI 200

Query: 191 TSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRATRKIGIAIATF 250
           T  ++ +VAR   +R++ ++    A +                 R H+AT  +   +  F
Sbjct: 201 TYYRIFKVARDQAKRINHISSWKAATI-----------------REHKATVTLAAVMGAF 243

Query: 251 LICFAPYVMTRLAE-LVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRPFR 302
           +IC+ PY    +   L     +N     +   L Y+ +  +P  Y+ L R FR
Sbjct: 244 IICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFR 296


>gi|4503905 galanin receptor 2 [Homo sapiens]
          Length = 387

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 82/326 (25%), Positives = 132/326 (40%), Gaps = 39/326 (11%)

Query: 5   EALLAGLL-VMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPF- 62
           EA++  LL  ++  V  + N LVL       +     + + ++NL +  L      +PF 
Sbjct: 24  EAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQA-VSTTNLFILNLGVADLCFILCCVPFQ 82

Query: 63  ----TLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRL 118
               TL G + G        C+ + FL       ++ ++AA+S D++LA+ +PL      
Sbjct: 83  ATIYTLDGWVFGSL-----LCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELR 137

Query: 119 RPRYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHA 178
            PR A   +G  WG SL FSG  L        +    C     P    PR  A       
Sbjct: 138 TPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCH----PAWSAPRRRAMDICTFV 193

Query: 179 VGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHR 238
             ++LP+ VL LT     R  R   + +D V   + A                 +R + +
Sbjct: 194 FSYLLPVLVLGLT---YARTLRYLWRAVDPVAAGSGA-----------------RRAKRK 233

Query: 239 ATRKIGIAIATFLICFAPY---VMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYS 295
            TR I I  A F +C+ P+   ++       P         ILS  ++Y+ +  +P  Y+
Sbjct: 234 VTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYA 293

Query: 296 LLRRPFRQVLAGMVHRLLKRTPRPAS 321
           L+ + FR+    +   LL R P  AS
Sbjct: 294 LVSKHFRKGFRTICAGLLGRAPGRAS 319


>gi|222080095 orexin receptor 1 [Homo sapiens]
          Length = 425

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 91/366 (24%), Positives = 150/366 (40%), Gaps = 57/366 (15%)

Query: 5   EALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTL 64
           E +L    V V  VAL+ N LV L    +  +RT  +   +VNLSL  +L+ A+ +P +L
Sbjct: 46  EWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRT-VTNYFIVNLSLADVLVTAICLPASL 104

Query: 65  LGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYAG 124
           L  +          C+VI +L     S A L+++ ++ D+W A+  PL +    R R  G
Sbjct: 105 LVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTAR-RARG 163

Query: 125 LLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAA----------FTA 174
            +LG  W  SLA          +   +A   CS  LP    R R  +          +  
Sbjct: 164 SILG-IWAVSLAI---------MVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPK 213

Query: 175 TLHAVGFVLP-LAVLCLTSLQVHRVARRHCQRMDTVTMKALA--------LLADL----- 220
             H+  F++  LA L L ++   ++ R+   R    T  AL          L DL     
Sbjct: 214 IYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLS 273

Query: 221 -HPSVRQRCL---IQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELV--PFVTVNAQ 274
             P  R R     ++Q R R +  + + + +  F +C+ P  +  + + V   F   + +
Sbjct: 274 GEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDR 333

Query: 275 WGI-----LSKCLTYSKAVADPFTYSLLRRPFRQVL----------AGMVHRLLKRTPRP 319
             +      S  L Y+ + A+P  Y+ L   FR+             G    L   +PR 
Sbjct: 334 EAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRS 393

Query: 320 ASTHDS 325
           +++H S
Sbjct: 394 SASHKS 399


>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
          Length = 408

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 90/370 (24%), Positives = 152/370 (41%), Gaps = 59/370 (15%)

Query: 3   PGEALLAGLLVMVLAVALLS-NALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMP 61
           P EA LAG L+ +  +A +  N LV++  A++  L+T  + V + +L+   L++  L +P
Sbjct: 34  PWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTMTN-VFVTSLAAADLVMGLLVVP 92

Query: 62  FTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPR 121
                 + G  P     C++   +D    + +  ++ AL+ D++LAV  PLRY   +  R
Sbjct: 93  PAATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKR 152

Query: 122 YAGLLLGCAWGQSLAFSGAALGCSW--LGYSSAFASCSLRLPPEPERPRFAAFTATL--- 176
            A   +   W  S A S A +   W  +G  +    C          PR  AF + +   
Sbjct: 153 CARTAVVLVWVVSAAVSFAPIMSQWWRVGADAEAQRCH-------SNPRCCAFASNMPYV 205

Query: 177 ---HAVGFVLPLAVLCLTSLQVHRVARRHC------------QRMDTVTMKALA------ 215
               +V F LPL V+     +V  VA R              +       ++LA      
Sbjct: 206 LLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRGELGRFPPEESPPAPSRSLAPAPVGT 265

Query: 216 -LLADLHPSVRQRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRL------AELVP- 267
               +  P+  +R       R HRA   +G+ + TF +C+ P+ +  +        LVP 
Sbjct: 266 CAPPEGVPACGRRPARLLPLREHRALCTLGLIMGTFTLCWLPFFLANVLRALGGPSLVPG 325

Query: 268 --FVTVNAQWGILSKCLTYSKAVADPFTYSL---LRRPFRQVLAGMVHRLLKRTPRPAST 322
             F+ +N  W      L Y+ +  +P  Y      R  FR++L     RL    P P + 
Sbjct: 326 PAFLALN--W------LGYANSAFNPLIYCRSPDFRSAFRRLLCRCGRRL---PPEPCAA 374

Query: 323 HDSSLDVAGM 332
              +L  +G+
Sbjct: 375 ARPALFPSGV 384


>gi|13236497 5-hydroxytryptamine receptor 5A [Homo sapiens]
          Length = 357

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 70/325 (21%), Positives = 135/325 (41%), Gaps = 31/325 (9%)

Query: 7   LLAGLLVMVLAVALLSNALVLLCCAYSAELRT--RASGVLLVNLSLGHLLLAALDMPFTL 64
           L+  LL  ++A     N LVL   A    +RT  R    L+ ++++  +L+AAL MP +L
Sbjct: 42  LILTLLGFLVAATFAWNLLVL---ATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSL 98

Query: 65  LGVMRGRT-PSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYA 123
           +  + GR        CQ+    D    + +  +V A++ D++ ++   + Y  R R   +
Sbjct: 99  VHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVS 158

Query: 124 GLLLGCAWGQSLAFSGAALGCSW-LGYSSAFASCSLRLPPEPERPRFAAFTATLHAVGFV 182
            +++   W  S   S A L   W   YS     C +        P +A F+       F 
Sbjct: 159 NVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVS-----REPSYAVFSTV---GAFY 210

Query: 183 LPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLI------------ 230
           LPL V+     ++++ A+       T ++  ++   ++  S +Q  ++            
Sbjct: 211 LPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQP 270

Query: 231 ----QQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSK 286
                ++++  RA   +GI I  F++C+ P+ +T L   +    + A W  +   L YS 
Sbjct: 271 EGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSN 330

Query: 287 AVADPFTYSLLRRPFRQVLAGMVHR 311
           +  +P  Y+   + +         R
Sbjct: 331 SFFNPLIYTAFNKNYNSAFKNFFSR 355


>gi|4503383 dopamine receptor D1 [Homo sapiens]
          Length = 446

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 55/276 (19%), Positives = 121/276 (43%), Gaps = 17/276 (6%)

Query: 7   LLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTLLG 66
           L A  L +++   LL N LV         LR++ +   +++L++  LL+A L MP+  + 
Sbjct: 25  LTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVA 84

Query: 67  VMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYAGLL 126
            + G  P     C +    D   ++ + L++  +S D++ A+  P RY  ++ P+ A +L
Sbjct: 85  EIAGFWPFG-SFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFIL 143

Query: 127 LGCAWGQSLAFSGAALGCSW-----LGYSSAFASCSLRLPPEPERPRFAAFTATLHAVGF 181
           +  AW  S+  S   +  SW        S   A+         +      +  +   + F
Sbjct: 144 ISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISF 203

Query: 182 VLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALL---------ADLHPSVRQRCLIQQ 232
            +P+A++ +T  +++R+A++  +R+  +   A+              +  S  +      
Sbjct: 204 YIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMS 263

Query: 233 KRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPF 268
            +R  +  + + + +  F+ C+ P+ +  L  ++PF
Sbjct: 264 FKRETKVLKTLSVIMGVFVCCWLPFFI--LNCILPF 297


>gi|222080109 orexin receptor 2 [Homo sapiens]
          Length = 444

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 75/326 (23%), Positives = 137/326 (42%), Gaps = 38/326 (11%)

Query: 7   LLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTLLG 66
           L+AG ++ V  VAL+ N LV +    +  +RT  +   +VNLSL  +L+    +P TL+ 
Sbjct: 57  LIAGYII-VFVVALIGNVLVCVAVWKNHHMRT-VTNYFIVNLSLADVLVTITCLPATLVV 114

Query: 67  VMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRL-RPRYAGL 125
            +          C+VI +L T   S + L+++ ++ D+W A+  PL +     R R + +
Sbjct: 115 DITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIV 174

Query: 126 LLGCAWGQSLAFSGAALGCSWL-----GYSSAFASCSLRLPPE--PERPRFAAFTATLHA 178
           ++       +      + CS +       ++ F  C  R   E  P+      F  T   
Sbjct: 175 IIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVT--- 231

Query: 179 VGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQR----------- 227
             ++ PL ++ L  LQ+ R  +  C+++   +         L P  + R           
Sbjct: 232 --YMAPLCLMVLAYLQIFR--KLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMS 287

Query: 228 ---CLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQ-------WGI 277
                I+Q R R +  R + I +  F IC+ P  +  + + V  +  + +       W  
Sbjct: 288 AVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFT 347

Query: 278 LSKCLTYSKAVADPFTYSLLRRPFRQ 303
            S  L Y+ + A+P  Y+ L   FR+
Sbjct: 348 FSHWLVYANSAANPIIYNFLSGKFRE 373


>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
          Length = 432

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 77/370 (20%), Positives = 152/370 (41%), Gaps = 56/370 (15%)

Query: 5   EALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPF-T 63
           + ++  +L ++  + +  N LV++   +  +LR + S  L+V+L+L  L +A   MPF +
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFVKKLR-QPSNYLIVSLALADLSVAVAVMPFVS 139

Query: 64  LLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYA 123
           +  ++ G+       C V   +D    + + +++  +S D++L +  PL Y  R   +  
Sbjct: 140 VTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCM 199

Query: 124 GLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVGFVL 183
             ++   W  S + +   L   W    +    C +         +   +T    AV F +
Sbjct: 200 AKMILSVWLLSASITLPPL-FGWAQNVNDDKVCLIS--------QDFGYTIYSTAVAFYI 250

Query: 184 PLAVLCLTSLQVHRVARRHCQ--------RMDTVTMKALALLADLHPSVRQ-----RCLI 230
           P++V+     Q+++ AR+           R++  ++ AL  +  L   V +     R L 
Sbjct: 251 PMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLK 310

Query: 231 QQKR------RRHRATRKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKC--- 281
            +++      R  +A   +GI +  F +C+ P+ +   A   PF+      G    C   
Sbjct: 311 HERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTAR--PFIC-----GTSCSCIPL 363

Query: 282 --------LTYSKAVADPFTYSLLRRPFRQVLAGMVHRLLKRTPRPASTHDSSLDVAGMV 333
                   L Y+ ++ +PF Y+   R  R     ++    +   R        L  AGM 
Sbjct: 364 WVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR-------KLSAAGM- 415

Query: 334 HQLLKRTPRP 343
           H+ LK   RP
Sbjct: 416 HEALKLAERP 425


>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
          Length = 479

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 77/370 (20%), Positives = 152/370 (41%), Gaps = 56/370 (15%)

Query: 5   EALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPF-T 63
           + ++  +L ++  + +  N LV++   +  +LR + S  L+V+L+L  L +A   MPF +
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFVKKLR-QPSNYLIVSLALADLSVAVAVMPFVS 139

Query: 64  LLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYA 123
           +  ++ G+       C V   +D    + + +++  +S D++L +  PL Y  R   +  
Sbjct: 140 VTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCM 199

Query: 124 GLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVGFVL 183
             ++   W  S + +   L   W    +    C +         +   +T    AV F +
Sbjct: 200 AKMILSVWLLSASITLPPL-FGWAQNVNDDKVCLIS--------QDFGYTIYSTAVAFYI 250

Query: 184 PLAVLCLTSLQVHRVARRHCQ--------RMDTVTMKALALLADLHPSVRQ-----RCLI 230
           P++V+     Q+++ AR+           R++  ++ AL  +  L   V +     R L 
Sbjct: 251 PMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLK 310

Query: 231 QQKR------RRHRATRKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKC--- 281
            +++      R  +A   +GI +  F +C+ P+ +   A   PF+      G    C   
Sbjct: 311 HERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTAR--PFIC-----GTSCSCIPL 363

Query: 282 --------LTYSKAVADPFTYSLLRRPFRQVLAGMVHRLLKRTPRPASTHDSSLDVAGMV 333
                   L Y+ ++ +PF Y+   R  R     ++    +   R        L  AGM 
Sbjct: 364 WVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR-------KLSAAGM- 415

Query: 334 HQLLKRTPRP 343
           H+ LK   RP
Sbjct: 416 HEALKLAERP 425


>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
          Length = 445

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 77/370 (20%), Positives = 152/370 (41%), Gaps = 56/370 (15%)

Query: 5   EALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPF-T 63
           + ++  +L ++  + +  N LV++   +  +LR + S  L+V+L+L  L +A   MPF +
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFVKKLR-QPSNYLIVSLALADLSVAVAVMPFVS 139

Query: 64  LLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYA 123
           +  ++ G+       C V   +D    + + +++  +S D++L +  PL Y  R   +  
Sbjct: 140 VTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCM 199

Query: 124 GLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVGFVL 183
             ++   W  S + +   L   W    +    C +         +   +T    AV F +
Sbjct: 200 AKMILSVWLLSASITLPPL-FGWAQNVNDDKVCLIS--------QDFGYTIYSTAVAFYI 250

Query: 184 PLAVLCLTSLQVHRVARRHCQ--------RMDTVTMKALALLADLHPSVRQ-----RCLI 230
           P++V+     Q+++ AR+           R++  ++ AL  +  L   V +     R L 
Sbjct: 251 PMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLK 310

Query: 231 QQKR------RRHRATRKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKC--- 281
            +++      R  +A   +GI +  F +C+ P+ +   A   PF+      G    C   
Sbjct: 311 HERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTAR--PFIC-----GTSCSCIPL 363

Query: 282 --------LTYSKAVADPFTYSLLRRPFRQVLAGMVHRLLKRTPRPASTHDSSLDVAGMV 333
                   L Y+ ++ +PF Y+   R  R     ++    +   R        L  AGM 
Sbjct: 364 WVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINR-------KLSAAGM- 415

Query: 334 HQLLKRTPRP 343
           H+ LK   RP
Sbjct: 416 HEALKLAERP 425


>gi|4557861 somatostatin receptor 3 [Homo sapiens]
          Length = 418

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 90/341 (26%), Positives = 140/341 (41%), Gaps = 59/341 (17%)

Query: 2   GPGEALLA--GLLV-----MVLAVALLSNALVLLCCAYSAELRTRAS----GVLLVNLSL 50
           GP  A LA  G+L+     +V  V LL N+LV+        LR  AS     V ++NL+L
Sbjct: 34  GPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVV-----LRHTASPSVTNVYILNLAL 88

Query: 51  GHLLLAALDMPFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGF 110
              L   L +PF          P     C+++  +D      +   +  +S D++LAV  
Sbjct: 89  ADELFM-LGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVH 147

Query: 111 PLRYAGRLRPRYAGLLLGCAWGQS-------LAFSGAALGCSWLGYSSAFASCSLRLPPE 163
           P R A       A  +    W  S       + FSG   G S         +C ++ P E
Sbjct: 148 PTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMS---------TCHMQWP-E 197

Query: 164 PERPRFAAFTATLHAVGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPS 223
           P     A F     A+GF  PL V+CL  L +    R   +R+               PS
Sbjct: 198 PAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV-------------WAPS 244

Query: 224 VRQRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELV-PFVTVNAQWGI--LSK 280
            ++R     +R   R TR +   +A F++C+ P+ +  +  +V P     A +G+  L  
Sbjct: 245 CQRR-----RRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVV 299

Query: 281 CLTYSKAVADPFTYSLL----RRPFRQVLAGMVHRLLKRTP 317
            L Y+ + A+P  Y  L    ++ FR+VL     R+  + P
Sbjct: 300 ALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEP 340


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 67/279 (24%), Positives = 124/279 (44%), Gaps = 40/279 (14%)

Query: 6   ALLAGLLV-MVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTL 64
           A+  GL++   +  A++ N LV+L  A +  LRT  +   +VNL++  LLL+   +PF+ 
Sbjct: 45  AISVGLVLGAFILFAIVGNILVILSVACNRHLRT-PTNYFIVNLAMADLLLSFTVLPFSA 103

Query: 65  LGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYAG 124
              + G        C +   +D    + + LS+ A+S D+++ V + L+Y   +  R A 
Sbjct: 104 ALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAI 163

Query: 125 LLLGCAWGQSLAFSGAALGCSWLGYSSAFAS----CSLRLPPEPERPRFAAFTATLHAVG 180
           L L   W  S   S   L    LG+     +    C +      E P +A F++      
Sbjct: 164 LALLSVWVLSTVISIGPL----LGWKEPAPNDDKECGV-----TEEPFYALFSS---LGS 211

Query: 181 FVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQR-----CLIQQKRR 235
           F +PLAV+ +   +V+ VA+R  + ++   MK ++   +L   +  +      L   K +
Sbjct: 212 FYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAK 271

Query: 236 RH-----------------RATRKIGIAIATFLICFAPY 257
            H                 +A + +GI +  F++C+ P+
Sbjct: 272 GHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPF 310


>gi|223633986 trace amine associated receptor 5 [Homo sapiens]
          Length = 337

 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 71/309 (22%), Positives = 126/309 (40%), Gaps = 41/309 (13%)

Query: 6   ALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTLL 65
           A  AG+L++VL      N  V    +Y   L T  +  LL++L+L  + L  L +P + +
Sbjct: 40  ACAAGMLIIVLG-----NVFVAFAVSYFKALHT-PTNFLLLSLALADMFLGLLVLPLSTI 93

Query: 66  GVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYAGL 125
             +          C++  +LDT     +   +  +S D+  A+  PL Y  +   R A  
Sbjct: 94  RSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALR 153

Query: 126 LLGCAWGQSLAFSGAALG--------CSWLGYSSAFASCSLRLPPEPERPRFAAFTATLH 177
            +   WG   A++   L           WL       SC L L           F   L+
Sbjct: 154 YILAGWGVPAAYTSLFLYTDVVETRLSQWLEEMPCVGSCQLLL---------NKFWGWLN 204

Query: 178 AVGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRH 237
              F +P  ++    +++  VA R  Q++ T++ K+LA  A               +   
Sbjct: 205 FPLFFVPCLIMISLYVKIFVVATRQAQQITTLS-KSLAGAA---------------KHER 248

Query: 238 RATRKIGIAIATFLICFAPYVM-TRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSL 296
           +A + +GIA+  +L+C+ P+ + T +  L+ F+T    + I      Y  +  +P  Y  
Sbjct: 249 KAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFI-WFAYFNSACNPIIYVF 307

Query: 297 LRRPFRQVL 305
             + FR+ L
Sbjct: 308 SYQWFRKAL 316


>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
          Length = 446

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 71/355 (20%), Positives = 141/355 (39%), Gaps = 40/355 (11%)

Query: 8   LAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTLLGV 67
           +  L  +V  V L  N LV+       +++T A+ + + NL+L   L A   +PF  +  
Sbjct: 73  IMALYSIVCVVGLFGNFLVMYVIVRYTKMKT-ATNIYIFNLALADAL-ATSTLPFQSVNY 130

Query: 68  MRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYAGLLL 127
           + G  P     C+++  +D +    +  ++  +S D+++AV  P++      PR A ++ 
Sbjct: 131 LMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIIN 190

Query: 128 GCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVGFVLPLAV 187
            C W  S A     +  +   Y      C+L     P           +    F++P+ +
Sbjct: 191 VCNWILSSAIGLPVMFMATTKYRQGSIDCTLTF-SHPTWYWENLLKICVFIFAFIMPVLI 249

Query: 188 LCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRATRKIGIAI 247
           + +            C  +  + +K++ +L+            ++ R   R TR + + +
Sbjct: 250 ITV------------CYGLMILRLKSVRMLSGSK---------EKDRNLRRITRMVLVVV 288

Query: 248 ATFLICFAP---YVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRPFRQV 304
           A F++C+ P   YV+ +    +P  T           L Y+ +  +P  Y+ L   F+  
Sbjct: 289 AVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFK-- 346

Query: 305 LAGMVHRLLKRTPRPASTHDSSLDVAGMVHQLLKRTPRPASTHNGSVDTENDSCL 359
                 R  +    P S++    + +  + Q  +  P  A+T    VD  N  CL
Sbjct: 347 ------RCFREFCIPTSSNIEQQN-STRIRQNTRDHPSTANT----VDRTNHQCL 390


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.137    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,446,412
Number of Sequences: 37866
Number of extensions: 559965
Number of successful extensions: 2589
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 253
Number of HSP's successfully gapped in prelim test: 237
Number of HSP's that attempted gapping in prelim test: 2072
Number of HSP's gapped (non-prelim): 580
length of query: 363
length of database: 18,247,518
effective HSP length: 104
effective length of query: 259
effective length of database: 14,309,454
effective search space: 3706148586
effective search space used: 3706148586
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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