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Search of human proteins with 33695097
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33695097 G protein-coupled receptor 35 [Homo sapiens]
(309 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33695097 G protein-coupled receptor 35 [Homo sapiens] 625 e-179
gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] 150 1e-36
gi|29171311 G protein-coupled receptor 109A [Homo sapiens] 142 4e-34
gi|33695107 G protein-coupled receptor 55 [Homo sapiens] 142 5e-34
gi|157738694 G protein-coupled receptor 109B [Homo sapiens] 140 1e-33
gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 134 8e-32
gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 134 8e-32
gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 134 8e-32
gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens] 133 2e-31
gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens] 133 2e-31
gi|28872720 purinergic receptor P2Y2 [Homo sapiens] 121 9e-28
gi|28872745 purinergic receptor P2Y2 [Homo sapiens] 121 9e-28
gi|28872743 purinergic receptor P2Y2 [Homo sapiens] 121 9e-28
gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens] 121 9e-28
gi|14211851 G protein-coupled receptor 81 [Homo sapiens] 120 1e-27
gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] 116 2e-26
gi|4557359 bradykinin receptor B2 [Homo sapiens] 114 8e-26
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 114 8e-26
gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 114 8e-26
gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 114 8e-26
gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 114 8e-26
gi|89257346 G protein-coupled receptor 20 [Homo sapiens] 113 2e-25
gi|4506241 platelet-activating factor receptor [Homo sapiens] 112 3e-25
gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens] 111 9e-25
gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens] 111 9e-25
gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens] 111 9e-25
gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens] 111 9e-25
gi|47271392 succinate receptor 1 [Homo sapiens] 111 9e-25
gi|4505557 purinergic receptor P2Y1 [Homo sapiens] 110 2e-24
gi|4885335 G protein-coupled receptor 4 [Homo sapiens] 108 5e-24
>gi|33695097 G protein-coupled receptor 35 [Homo sapiens]
Length = 309
Score = 625 bits (1612), Expect = e-179
Identities = 309/309 (100%), Positives = 309/309 (100%)
Query: 1 MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMT 60
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMT
Sbjct: 1 MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMT 60
Query: 61 NLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRH 120
NLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRH
Sbjct: 61 NLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRH 120
Query: 121 PLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGF 180
PLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGF
Sbjct: 121 PLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGF 180
Query: 181 YLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVR 240
YLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVR
Sbjct: 181 YLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVR 240
Query: 241 LAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKS 300
LAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKS
Sbjct: 241 LAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKS 300
Query: 301 QDSLCVTLA 309
QDSLCVTLA
Sbjct: 301 QDSLCVTLA 309
>gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens]
Length = 370
Score = 150 bits (379), Expect = 1e-36
Identities = 98/281 (34%), Positives = 156/281 (55%), Gaps = 22/281 (7%)
Query: 25 AYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPF-VLHSLR-- 81
A V+ +LGL+ NS++L+VFC RM+ +ET I++TNLAV+DL +CTLPF + ++
Sbjct: 44 AVYSVVFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRH 103
Query: 82 -DTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVL 140
DT LC++S +LTN Y S+ +T I+VDR++A+ +P R+R +R+ R +A VCA +
Sbjct: 104 WPFGDT-LCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGV 162
Query: 141 WVLVIGSLVARWLLGIQE---------GGFCFRSTRHNFNSMA--FPLLGFYLPLAVVVF 189
W+LV+ ++ L GF R + + + ++GF +PL + V
Sbjct: 163 WILVLSGGISASLFSTTNVNNATTTCFEGFSKRVWKTYLSKITIFIEVVGFIIPLILNVS 222
Query: 190 CSLKVVTALAQRPPTDVGQAEAT-RKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNAC 248
CS V+ L R P + Q +K +M+ ++ VFVVCF+P + L + V A
Sbjct: 223 CSSVVLRTL--RKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAI 280
Query: 249 --ALLETIRRALY-ITSKLSDANCCLDAICYYYMAKEFQEA 286
LE + +Y IT L+ NCC D YY+ + FQ++
Sbjct: 281 TNCFLERFAKIMYPITLCLATLNCCFDPFIYYFTLESFQKS 321
>gi|29171311 G protein-coupled receptor 109A [Homo sapiens]
Length = 363
Score = 142 bits (358), Expect = 4e-34
Identities = 93/274 (33%), Positives = 140/274 (51%), Gaps = 23/274 (8%)
Query: 27 LGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDT 86
LG+ + GLL N LALW+FC ++ W +RI++ NLAVAD L+ LPF++ + D
Sbjct: 34 LGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDW 93
Query: 87 PL----CQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWV 142
C+L + NR SI +T +AVDRY V HP A S R AA + +LW
Sbjct: 94 KFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWG 153
Query: 143 LVIGSLV--ARWLLGIQEGG--FCFR-STRHNFN-SMAFPLLGFYLPLAVVVFCSLKVVT 196
+ IG V + + IQ GG C S H F A LL F+LPL +++FCS +++
Sbjct: 154 ITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIW 213
Query: 197 ALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGW-------NACA 249
+L QR + + ++A + +VFV+CFLP + VR+ + W C
Sbjct: 214 SLRQR---QMDRHAKIKRAITFIMVVAIVFVICFLP---SVVVRIRIFWLLHTSGTQNCE 267
Query: 250 LLETIRRALYITSKLSDANCCLDAICYYYMAKEF 283
+ ++ A +IT + N LD + YY+ + F
Sbjct: 268 VYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301
>gi|33695107 G protein-coupled receptor 55 [Homo sapiens]
Length = 319
Score = 142 bits (357), Expect = 5e-34
Identities = 99/267 (37%), Positives = 144/267 (53%), Gaps = 16/267 (5%)
Query: 32 VLGLLLNSLALWVFCC----RMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTP 87
VLGLLLN LA+ F R + T IYM NLAV DL L+ +LPF + + S P
Sbjct: 32 VLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFP 91
Query: 88 -LCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLV-I 145
LC L + +Y + Y S+ + I++DR++A+R+PL LRSPR+ +C +WVLV
Sbjct: 92 SLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWT 151
Query: 146 GSLVARWLLGIQEGGFCFRSTRHNFNS--MAFPL--LGFYLPLAVVVFCSLKVVTALAQR 201
GS+ G E CF + + S + FPL GF LP+ ++ FC + + L R
Sbjct: 152 GSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGR 211
Query: 202 PPTDVGQAEATRKAA-RMVWANLLVFVVCFLPLHVGLTVRLAVGWN---ACALLETIRRA 257
D Q +KA + A+L VFVV FLP+H+G ++ V + C ++I
Sbjct: 212 --RDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFF 269
Query: 258 LYITSKLSDANCCLDAICYYYMAKEFQ 284
L ++ S+ NCCLD CYY++ KEF+
Sbjct: 270 LQLSMCFSNVNCCLDVFCYYFVIKEFR 296
>gi|157738694 G protein-coupled receptor 109B [Homo sapiens]
Length = 387
Score = 140 bits (353), Expect = 1e-33
Identities = 93/274 (33%), Positives = 139/274 (50%), Gaps = 23/274 (8%)
Query: 27 LGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDT 86
LG+ + GLL N LALW+FC ++ W +RI++ NLAVAD L+ LPFV+ SD
Sbjct: 34 LGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFVMDYYVRRSDW 93
Query: 87 PL----CQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWV 142
C+L ++ NR SI +T +AVDRY V HP A S AA + +LW
Sbjct: 94 KFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAAIISCLLWG 153
Query: 143 LVIGSLV--ARWLLGIQEG--GFCFR-STRHNFN-SMAFPLLGFYLPLAVVVFCSLKVVT 196
+ +G V + L IQ G C S H F A LL F+LPL +++FCS +++
Sbjct: 154 ITVGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEAMFLLEFFLPLGIILFCSARIIW 213
Query: 197 ALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGW-------NACA 249
+L QR + + ++A + +VFV+CFLP + VR+ + W C
Sbjct: 214 SLRQR---QMDRHAKIKRAITFIMVVAIVFVICFLP---SVVVRIHIFWLLHTSGTQNCE 267
Query: 250 LLETIRRALYITSKLSDANCCLDAICYYYMAKEF 283
+ ++ A +IT + N LD + YY+ + F
Sbjct: 268 VYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF 301
>gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 134 bits (338), Expect = 8e-32
Identities = 88/299 (29%), Positives = 157/299 (52%), Gaps = 25/299 (8%)
Query: 10 SSDLTWPPAIKLGFYAYL-GVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLC 68
SS + + K Y + ++ VLGL+ N +A+++F C ++ ET YM NLA++DL
Sbjct: 6 SSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLL 65
Query: 69 LLCTLPFVLHSLRDTSDTP----LCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRA 124
+ TLPF + T + P LC++S ++ TN Y SI +T I+VDR++A+ +P ++
Sbjct: 66 FVFTLPFRIFYFT-TRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKS 124
Query: 125 RGLRSPRQAAAVCAVLWVLVIGSLVARWLL------GIQEGGFCF----RSTRHNFNS-- 172
+ LR+ R A VC +W+ VIG + G CF +T + S
Sbjct: 125 KTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRI 184
Query: 173 -MAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATR-KAARMVWANLLVFVVCF 230
+ ++GF++PL + V CS V+ L + P + +++ + K +M++ +L++F CF
Sbjct: 185 VIFIEIVGFFIPLILNVTCSSMVLKTLTK--PVTLSRSKINKTKVLKMIFVHLIIFCFCF 242
Query: 231 LPLHVGLTVRLAVGWNA---CALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEA 286
+P ++ L + V C+++ +R IT ++ +NCC D I YY+ + Q +
Sbjct: 243 VPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNS 301
>gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 134 bits (338), Expect = 8e-32
Identities = 88/299 (29%), Positives = 157/299 (52%), Gaps = 25/299 (8%)
Query: 10 SSDLTWPPAIKLGFYAYL-GVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLC 68
SS + + K Y + ++ VLGL+ N +A+++F C ++ ET YM NLA++DL
Sbjct: 6 SSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLL 65
Query: 69 LLCTLPFVLHSLRDTSDTP----LCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRA 124
+ TLPF + T + P LC++S ++ TN Y SI +T I+VDR++A+ +P ++
Sbjct: 66 FVFTLPFRIFYFT-TRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKS 124
Query: 125 RGLRSPRQAAAVCAVLWVLVIGSLVARWLL------GIQEGGFCF----RSTRHNFNS-- 172
+ LR+ R A VC +W+ VIG + G CF +T + S
Sbjct: 125 KTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRI 184
Query: 173 -MAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATR-KAARMVWANLLVFVVCF 230
+ ++GF++PL + V CS V+ L + P + +++ + K +M++ +L++F CF
Sbjct: 185 VIFIEIVGFFIPLILNVTCSSMVLKTLTK--PVTLSRSKINKTKVLKMIFVHLIIFCFCF 242
Query: 231 LPLHVGLTVRLAVGWNA---CALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEA 286
+P ++ L + V C+++ +R IT ++ +NCC D I YY+ + Q +
Sbjct: 243 VPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNS 301
>gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 134 bits (338), Expect = 8e-32
Identities = 88/299 (29%), Positives = 157/299 (52%), Gaps = 25/299 (8%)
Query: 10 SSDLTWPPAIKLGFYAYL-GVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLC 68
SS + + K Y + ++ VLGL+ N +A+++F C ++ ET YM NLA++DL
Sbjct: 6 SSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLL 65
Query: 69 LLCTLPFVLHSLRDTSDTP----LCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRA 124
+ TLPF + T + P LC++S ++ TN Y SI +T I+VDR++A+ +P ++
Sbjct: 66 FVFTLPFRIFYFT-TRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKS 124
Query: 125 RGLRSPRQAAAVCAVLWVLVIGSLVARWLL------GIQEGGFCF----RSTRHNFNS-- 172
+ LR+ R A VC +W+ VIG + G CF +T + S
Sbjct: 125 KTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRI 184
Query: 173 -MAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATR-KAARMVWANLLVFVVCF 230
+ ++GF++PL + V CS V+ L + P + +++ + K +M++ +L++F CF
Sbjct: 185 VIFIEIVGFFIPLILNVTCSSMVLKTLTK--PVTLSRSKINKTKVLKMIFVHLIIFCFCF 242
Query: 231 LPLHVGLTVRLAVGWNA---CALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEA 286
+P ++ L + V C+++ +R IT ++ +NCC D I YY+ + Q +
Sbjct: 243 VPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNS 301
>gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens]
Length = 372
Score = 133 bits (335), Expect = 2e-31
Identities = 101/292 (34%), Positives = 145/292 (49%), Gaps = 30/292 (10%)
Query: 17 PAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLP-- 74
P +L Y ++L GL LN+LALWVF ++ + +YM NLA +DL +LP
Sbjct: 20 PTHRLHLVVY-SLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVR 78
Query: 75 ---FVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPR 131
+ LH LCQ + I+ N Y S + I VDRY A+ HPLR R LR PR
Sbjct: 79 LSYYALHHW--PFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPR 136
Query: 132 QAAAVCAVLWVLVIGSLV--------ARWLLGIQEGGFCFRS-TRHNFNSMAFPL----- 177
A +C +W L++ V +R E CF S + + PL
Sbjct: 137 VARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAE 196
Query: 178 -LGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVG 236
LGF LPLA VV+ S +V LA RP D Q++ RK R++ ANL++F++CF+P +
Sbjct: 197 ALGFLLPLAAVVYSSGRVFWTLA-RP--DATQSQRRRKTVRLLLANLVIFLLCFVPYNST 253
Query: 237 LTV----RLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQ 284
L V R + + + +R L + L+ ANC LD + YY+ A+ F+
Sbjct: 254 LAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFR 305
>gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens]
Length = 372
Score = 133 bits (335), Expect = 2e-31
Identities = 101/292 (34%), Positives = 145/292 (49%), Gaps = 30/292 (10%)
Query: 17 PAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLP-- 74
P +L Y ++L GL LN+LALWVF ++ + +YM NLA +DL +LP
Sbjct: 20 PTHRLHLVVY-SLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVR 78
Query: 75 ---FVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPR 131
+ LH LCQ + I+ N Y S + I VDRY A+ HPLR R LR PR
Sbjct: 79 LSYYALHHW--PFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPR 136
Query: 132 QAAAVCAVLWVLVIGSLV--------ARWLLGIQEGGFCFRS-TRHNFNSMAFPL----- 177
A +C +W L++ V +R E CF S + + PL
Sbjct: 137 VARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAE 196
Query: 178 -LGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVG 236
LGF LPLA VV+ S +V LA RP D Q++ RK R++ ANL++F++CF+P +
Sbjct: 197 ALGFLLPLAAVVYSSGRVFWTLA-RP--DATQSQRRRKTVRLLLANLVIFLLCFVPYNST 253
Query: 237 LTV----RLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQ 284
L V R + + + +R L + L+ ANC LD + YY+ A+ F+
Sbjct: 254 LAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFR 305
>gi|28872720 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 121 bits (303), Expect = 9e-28
Identities = 88/271 (32%), Positives = 135/271 (49%), Gaps = 25/271 (9%)
Query: 28 GVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTP 87
GV+ V GL LN++AL++F CR++ W + YM +LAV+D +LP +++ P
Sbjct: 41 GVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWP 100
Query: 88 ----LCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVL 143
LC+L + ++ TN Y SI +T I+V R + V PLR+ R A V +WVL
Sbjct: 101 FSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVL 160
Query: 144 VIG--SLVARWLLGIQEGGFCFRSTRHN------------FNSMAFPLLGFYLPLAVVVF 189
V+ + V ++ GG R T H+ ++S+ LL F +P AV++
Sbjct: 161 VLACQAPVLYFVTTSARGG---RVTCHDTSAPELFSRFVAYSSVMLGLL-FAVPFAVILV 216
Query: 190 CSLKVVTALAQRP-PTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGW--N 246
C + + L + T G A RK+ R + L VF +CFLP HV T+ +
Sbjct: 217 CYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDL 276
Query: 247 ACALLETIRRALYITSKLSDANCCLDAICYY 277
+C L I A +T L+ AN CLD + Y+
Sbjct: 277 SCHTLNAINMAYKVTRPLASANSCLDPVLYF 307
>gi|28872745 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 121 bits (303), Expect = 9e-28
Identities = 88/271 (32%), Positives = 135/271 (49%), Gaps = 25/271 (9%)
Query: 28 GVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTP 87
GV+ V GL LN++AL++F CR++ W + YM +LAV+D +LP +++ P
Sbjct: 41 GVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWP 100
Query: 88 ----LCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVL 143
LC+L + ++ TN Y SI +T I+V R + V PLR+ R A V +WVL
Sbjct: 101 FSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVL 160
Query: 144 VIG--SLVARWLLGIQEGGFCFRSTRHN------------FNSMAFPLLGFYLPLAVVVF 189
V+ + V ++ GG R T H+ ++S+ LL F +P AV++
Sbjct: 161 VLACQAPVLYFVTTSARGG---RVTCHDTSAPELFSRFVAYSSVMLGLL-FAVPFAVILV 216
Query: 190 CSLKVVTALAQRP-PTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGW--N 246
C + + L + T G A RK+ R + L VF +CFLP HV T+ +
Sbjct: 217 CYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDL 276
Query: 247 ACALLETIRRALYITSKLSDANCCLDAICYY 277
+C L I A +T L+ AN CLD + Y+
Sbjct: 277 SCHTLNAINMAYKVTRPLASANSCLDPVLYF 307
>gi|28872743 purinergic receptor P2Y2 [Homo sapiens]
Length = 377
Score = 121 bits (303), Expect = 9e-28
Identities = 88/271 (32%), Positives = 135/271 (49%), Gaps = 25/271 (9%)
Query: 28 GVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTP 87
GV+ V GL LN++AL++F CR++ W + YM +LAV+D +LP +++ P
Sbjct: 41 GVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWP 100
Query: 88 ----LCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVL 143
LC+L + ++ TN Y SI +T I+V R + V PLR+ R A V +WVL
Sbjct: 101 FSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVL 160
Query: 144 VIG--SLVARWLLGIQEGGFCFRSTRHN------------FNSMAFPLLGFYLPLAVVVF 189
V+ + V ++ GG R T H+ ++S+ LL F +P AV++
Sbjct: 161 VLACQAPVLYFVTTSARGG---RVTCHDTSAPELFSRFVAYSSVMLGLL-FAVPFAVILV 216
Query: 190 CSLKVVTALAQRP-PTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGW--N 246
C + + L + T G A RK+ R + L VF +CFLP HV T+ +
Sbjct: 217 CYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDL 276
Query: 247 ACALLETIRRALYITSKLSDANCCLDAICYY 277
+C L I A +T L+ AN CLD + Y+
Sbjct: 277 SCHTLNAINMAYKVTRPLASANSCLDPVLYF 307
>gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens]
Length = 346
Score = 121 bits (303), Expect = 9e-28
Identities = 82/297 (27%), Positives = 144/297 (48%), Gaps = 15/297 (5%)
Query: 2 NGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTN 61
NGT++ S + T + F ++ G+L N L+++VF ++ T ++M N
Sbjct: 20 NGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLN 79
Query: 62 LAVADLCLLCTLPFVL-HSLRDTS----DTPLCQLSQGIYLTNRYMSISLVTAIAVDRYV 116
LA++DL + TLPF + LR ++ D +S +Y+ N Y SI +T ++V R++
Sbjct: 80 LAISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYV-NMYSSIYFLTVLSVVRFL 138
Query: 117 AVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMA-- 174
A+ HP R + S R A +C ++W+L++ S + G ++ G N +A
Sbjct: 139 AMVHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSEQNGSVTSCLELNLYKIAKL 198
Query: 175 ------FPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVV 228
++G LP + C L ++ L + + G + RKA + L++F +
Sbjct: 199 QTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRVSHRKALTTIIITLIIFFL 258
Query: 229 CFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQE 285
CFLP H TV L W + + +AL IT L+ AN C + + YY+ + F++
Sbjct: 259 CFLPYHTLRTVHLTT-WKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGENFKD 314
>gi|14211851 G protein-coupled receptor 81 [Homo sapiens]
Length = 346
Score = 120 bits (302), Expect = 1e-27
Identities = 90/269 (33%), Positives = 133/269 (49%), Gaps = 21/269 (7%)
Query: 29 VLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPF-VLHSLRDT---- 83
V VLG L N +AL FC M+ W + +Y+ NLAVAD L+ LPF + LR
Sbjct: 24 VAFVLGALGNGVALCGFCFHMKTWKPSTVYLFNLAVADFLLMICLPFRTDYYLRRRHWAF 83
Query: 84 SDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVL 143
D P C++ NR SI +T +A DRY V HP A S R AA + LW L
Sbjct: 84 GDIP-CRVGLFTLAMNRAGSIVFLTVVAADRYFKVVHPHHAVNTISTRVAAGIVCTLWAL 142
Query: 144 VIGSLVARWL---LGIQEGGFCFRS----TRHNFNSMAFPLLGFYLPLAVVVFCSLKVVT 196
VI V L L +QE S + + ++ + F L F++PL +++FCS K+V
Sbjct: 143 VILGTVYLLLENHLCVQETAVSCESFIMESANGWHDIMFQ-LEFFMPLGIILFCSFKIVW 201
Query: 197 ALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWN--ACALLETI 254
+L +R + + +KA R + +VF+ C+LP ++ RL W + A ++
Sbjct: 202 SLRRR--QQLARQARMKKATRFIMVVAIVFITCYLP---SVSARLYFLWTVPSSACDPSV 256
Query: 255 RRALYITSKLSDANCCLDAICYYYMAKEF 283
AL+IT + N LD + YY+ + F
Sbjct: 257 HGALHITLSFTYMNSMLDPLVYYFSSPSF 285
>gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens]
Length = 365
Score = 116 bits (291), Expect = 2e-26
Identities = 83/273 (30%), Positives = 135/273 (49%), Gaps = 19/273 (6%)
Query: 29 VLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTP- 87
V+ VLGL LN+ LW+F R++ W T YM +LA++D + +LP +++ + P
Sbjct: 44 VVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPF 103
Query: 88 ---LCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLV 144
+C+ + ++ N Y S+ +T I+V RY+ + HPLRA PR A +C +W++V
Sbjct: 104 GTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVV 163
Query: 145 IGSLVAR-WLLGIQEGG---FCFRSTRH-------NFNSMAFPLLGFYLPLAVVVFCSLK 193
G LV + + G C +TR +F+S LL F +P V + C
Sbjct: 164 AGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLL-FGVPCLVTLVCYGL 222
Query: 194 VVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTV-RLAVGWNA-CALL 251
+ L Q P Q+ + ++ R + L VF VCF+P H+ T+ LA A C +L
Sbjct: 223 MARRLYQ-PLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVL 281
Query: 252 ETIRRALYITSKLSDANCCLDAICYYYMAKEFQ 284
+ +T L+ AN CLD + Y +++
Sbjct: 282 NIVNVVYKVTRPLASANSCLDPVLYLLTGDKYR 314
>gi|4557359 bradykinin receptor B2 [Homo sapiens]
Length = 391
Score = 114 bits (286), Expect = 8e-26
Identities = 87/307 (28%), Positives = 142/307 (46%), Gaps = 21/307 (6%)
Query: 1 MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMT 60
+NGT+ + W + +L VL VL L N L VFC T IY+
Sbjct: 38 LNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLG 97
Query: 61 NLAVADLCLLCTLPFVLHSLRDTSD----TPLCQLSQGIYLTNRYMSISLVTAIAVDRYV 116
NLA ADL L C LPF ++ + D LC++ I N Y SI + +++DRY+
Sbjct: 98 NLAAADLILACGLPFWAITISNNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYL 157
Query: 117 AVRHPLRARGLRSPRQAAAVCAVLW--VLVIGS--LVARWLLGIQEGGF----CFRSTR- 167
A+ + +R R A V+W L++ S LV R + + G C S
Sbjct: 158 ALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPS 217
Query: 168 ---HNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLL 224
F +M ++GF LPL+V+ FC+++++ L + + R+A +V LL
Sbjct: 218 LIWEVFTNMLLNVVGFLLPLSVITFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLL 277
Query: 225 VFVVCFLPLHVGLTV----RLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMA 280
+F++C+LP + + RL + ++C I I S ++ +N CL+ + Y +
Sbjct: 278 LFIICWLPFQISTFLDTLHRLGI-LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVG 336
Query: 281 KEFQEAS 287
K F++ S
Sbjct: 337 KRFRKKS 343
>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 114 bits (286), Expect = 8e-26
Identities = 88/296 (29%), Positives = 139/296 (46%), Gaps = 20/296 (6%)
Query: 4 TYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLA 63
T CG P + F ++ + +L L+ N+LALW+F + T +++ +LA
Sbjct: 19 TAEQCGQET----PLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLA 74
Query: 64 VADLCLLCTLPFVLHSLRDTSDTPL----CQLSQGIYLTNRYMSISLVTAIAVDRYVAVR 119
VADL + LP L + P C+L+ ++ N Y SI +T I+ DR++A+
Sbjct: 75 VADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIV 134
Query: 120 HPLRARGLRSPRQAAAVCAVLWVLVIGS----LVARWLLGIQEGGFCFRSTRHNFNSMAF 175
HP+++ LR P A CA LWV+V + LV+ + C + R + A
Sbjct: 135 HPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHAL 194
Query: 176 PLL--GFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPL 233
L F P V C L ++ +L Q + KA RM+ L +F+VCF+P
Sbjct: 195 VSLAVAFTFPFITTVTCYLLIIRSLRQGLRV---EKRLKTKAVRMIAIVLAIFLVCFVPY 251
Query: 234 HVGLTV---RLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEA 286
HV +V +CA + A ITS L+ N LD I Y+++A++F+ A
Sbjct: 252 HVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHA 307
>gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 114 bits (286), Expect = 8e-26
Identities = 88/296 (29%), Positives = 139/296 (46%), Gaps = 20/296 (6%)
Query: 4 TYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLA 63
T CG P + F ++ + +L L+ N+LALW+F + T +++ +LA
Sbjct: 19 TAEQCGQET----PLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLA 74
Query: 64 VADLCLLCTLPFVLHSLRDTSDTPL----CQLSQGIYLTNRYMSISLVTAIAVDRYVAVR 119
VADL + LP L + P C+L+ ++ N Y SI +T I+ DR++A+
Sbjct: 75 VADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIV 134
Query: 120 HPLRARGLRSPRQAAAVCAVLWVLVIGS----LVARWLLGIQEGGFCFRSTRHNFNSMAF 175
HP+++ LR P A CA LWV+V + LV+ + C + R + A
Sbjct: 135 HPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHAL 194
Query: 176 PLL--GFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPL 233
L F P V C L ++ +L Q + KA RM+ L +F+VCF+P
Sbjct: 195 VSLAVAFTFPFITTVTCYLLIIRSLRQGLRV---EKRLKTKAVRMIAIVLAIFLVCFVPY 251
Query: 234 HVGLTV---RLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEA 286
HV +V +CA + A ITS L+ N LD I Y+++A++F+ A
Sbjct: 252 HVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHA 307
>gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 114 bits (286), Expect = 8e-26
Identities = 88/296 (29%), Positives = 139/296 (46%), Gaps = 20/296 (6%)
Query: 4 TYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLA 63
T CG P + F ++ + +L L+ N+LALW+F + T +++ +LA
Sbjct: 47 TAEQCGQET----PLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLA 102
Query: 64 VADLCLLCTLPFVLHSLRDTSDTPL----CQLSQGIYLTNRYMSISLVTAIAVDRYVAVR 119
VADL + LP L + P C+L+ ++ N Y SI +T I+ DR++A+
Sbjct: 103 VADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIV 162
Query: 120 HPLRARGLRSPRQAAAVCAVLWVLVIGS----LVARWLLGIQEGGFCFRSTRHNFNSMAF 175
HP+++ LR P A CA LWV+V + LV+ + C + R + A
Sbjct: 163 HPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHAL 222
Query: 176 PLL--GFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPL 233
L F P V C L ++ +L Q + KA RM+ L +F+VCF+P
Sbjct: 223 VSLAVAFTFPFITTVTCYLLIIRSLRQGLRV---EKRLKTKAVRMIAIVLAIFLVCFVPY 279
Query: 234 HVGLTV---RLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEA 286
HV +V +CA + A ITS L+ N LD I Y+++A++F+ A
Sbjct: 280 HVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHA 335
>gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 114 bits (286), Expect = 8e-26
Identities = 88/296 (29%), Positives = 139/296 (46%), Gaps = 20/296 (6%)
Query: 4 TYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLA 63
T CG P + F ++ + +L L+ N+LALW+F + T +++ +LA
Sbjct: 47 TAEQCGQET----PLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLA 102
Query: 64 VADLCLLCTLPFVLHSLRDTSDTPL----CQLSQGIYLTNRYMSISLVTAIAVDRYVAVR 119
VADL + LP L + P C+L+ ++ N Y SI +T I+ DR++A+
Sbjct: 103 VADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIV 162
Query: 120 HPLRARGLRSPRQAAAVCAVLWVLVIGS----LVARWLLGIQEGGFCFRSTRHNFNSMAF 175
HP+++ LR P A CA LWV+V + LV+ + C + R + A
Sbjct: 163 HPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHAL 222
Query: 176 PLL--GFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPL 233
L F P V C L ++ +L Q + KA RM+ L +F+VCF+P
Sbjct: 223 VSLAVAFTFPFITTVTCYLLIIRSLRQGLRV---EKRLKTKAVRMIAIVLAIFLVCFVPY 279
Query: 234 HVGLTV---RLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEA 286
HV +V +CA + A ITS L+ N LD I Y+++A++F+ A
Sbjct: 280 HVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHA 335
>gi|89257346 G protein-coupled receptor 20 [Homo sapiens]
Length = 358
Score = 113 bits (283), Expect = 2e-25
Identities = 84/269 (31%), Positives = 125/269 (46%), Gaps = 14/269 (5%)
Query: 17 PAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFV 76
P + L A G + + GL+LN LAL+VFCCR + T + IY NL V DL + +LP
Sbjct: 50 PGLWLALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTR 109
Query: 77 LHSLRDTSDTPLCQLSQGI-YLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAA 135
C + Y N + SI +T I VDRY+A+ P +R R P A A
Sbjct: 110 FAVYYGARGCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARA 169
Query: 136 VCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVV 195
VCA +W + V +LG+ C R A +L F LPL V+ + +++
Sbjct: 170 VCAFVW--LAAGAVTLSVLGVTGSRPCCR-------VFALTVLEFLLPLLVISVFTGRIM 220
Query: 196 TALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIR 255
AL++ G+ R A +++ L++F+VCF P H ++AV T
Sbjct: 221 CALSRPGLLHQGRQRRVR-AMQLLLTVLIIFLVCFTPFHAR---QVAVALWPDMPHHTSL 276
Query: 256 RALYITSKLSDANCCLDAICYYYMAKEFQ 284
++ LS N C+D I Y ++ FQ
Sbjct: 277 VVYHVAVTLSSLNSCMDPIVYCFVTSGFQ 305
>gi|4506241 platelet-activating factor receptor [Homo sapiens]
Length = 342
Score = 112 bits (281), Expect = 3e-25
Identities = 77/281 (27%), Positives = 139/281 (49%), Gaps = 26/281 (9%)
Query: 29 VLLVLGLLLNSLALWVFC----CRMQQWTETRIYMTNLAVADLCLLCTLPF--VLHSLRD 82
++ VLG++ N LWVF C+ ++ E +I+M NL +AD+ L TLP V + +
Sbjct: 24 IIFVLGVIANGYVLWVFARLYPCK--KFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQG 81
Query: 83 TSDTP--LCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVL 140
P LC ++ ++ N Y S++ + I +R+ AV P++ + ++ ++ V+
Sbjct: 82 NWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSLVI 141
Query: 141 WVLVIGSLVARWLLG----IQEGGFCFRSTR--HNFNSMAFPLL--------GFYLPLAV 186
WV ++G+ +L + + TR ++ + P+L F+L +
Sbjct: 142 WVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIFIVFSFFLVFLI 201
Query: 187 VVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLH-VGLTVRLA-VG 244
++FC+L ++ L +P AE R+A MV L VF++CF+P H V L LA +G
Sbjct: 202 ILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELG 261
Query: 245 WNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQE 285
+ + I A +T L NC LD + Y ++ K+F++
Sbjct: 262 FQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRK 302
>gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 111 bits (277), Expect = 9e-25
Identities = 83/274 (30%), Positives = 124/274 (45%), Gaps = 19/274 (6%)
Query: 30 LLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPL- 88
+L GL LN + C + T T +Y NLA+ADL C+LP ++++ P
Sbjct: 36 VLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFG 95
Query: 89 ---CQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAA-AVCAVLWVLV 144
C+L + ++ N + SI +T I+ RY+ + HPL R R+AA VC +W+ V
Sbjct: 96 DFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAV 155
Query: 145 IGSLVARWLL---GIQEG-GFCF------RSTRHNFNSMAFPLLGFYLPLAVVVFCSLKV 194
+ + GIQ C+ +T + MA ++GF LP A ++ C +
Sbjct: 156 TTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLL 215
Query: 195 VTALA-QRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWN---ACAL 250
L Q P + E KAARM F + FLP H+ T LAV C +
Sbjct: 216 ACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTV 275
Query: 251 LETIRRALYITSKLSDANCCLDAICYYYMAKEFQ 284
LE A T + AN LD I +Y+ K+F+
Sbjct: 276 LEAFAAAYKGTRPFASANSVLDPILFYFTQKKFR 309
>gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 111 bits (277), Expect = 9e-25
Identities = 83/274 (30%), Positives = 124/274 (45%), Gaps = 19/274 (6%)
Query: 30 LLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPL- 88
+L GL LN + C + T T +Y NLA+ADL C+LP ++++ P
Sbjct: 36 VLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFG 95
Query: 89 ---CQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAA-AVCAVLWVLV 144
C+L + ++ N + SI +T I+ RY+ + HPL R R+AA VC +W+ V
Sbjct: 96 DFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAV 155
Query: 145 IGSLVARWLL---GIQEG-GFCF------RSTRHNFNSMAFPLLGFYLPLAVVVFCSLKV 194
+ + GIQ C+ +T + MA ++GF LP A ++ C +
Sbjct: 156 TTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLL 215
Query: 195 VTALA-QRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWN---ACAL 250
L Q P + E KAARM F + FLP H+ T LAV C +
Sbjct: 216 ACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTV 275
Query: 251 LETIRRALYITSKLSDANCCLDAICYYYMAKEFQ 284
LE A T + AN LD I +Y+ K+F+
Sbjct: 276 LEAFAAAYKGTRPFASANSVLDPILFYFTQKKFR 309
>gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 111 bits (277), Expect = 9e-25
Identities = 83/274 (30%), Positives = 124/274 (45%), Gaps = 19/274 (6%)
Query: 30 LLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPL- 88
+L GL LN + C + T T +Y NLA+ADL C+LP ++++ P
Sbjct: 36 VLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFG 95
Query: 89 ---CQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAA-AVCAVLWVLV 144
C+L + ++ N + SI +T I+ RY+ + HPL R R+AA VC +W+ V
Sbjct: 96 DFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAV 155
Query: 145 IGSLVARWLL---GIQEG-GFCF------RSTRHNFNSMAFPLLGFYLPLAVVVFCSLKV 194
+ + GIQ C+ +T + MA ++GF LP A ++ C +
Sbjct: 156 TTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLL 215
Query: 195 VTALA-QRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWN---ACAL 250
L Q P + E KAARM F + FLP H+ T LAV C +
Sbjct: 216 ACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTV 275
Query: 251 LETIRRALYITSKLSDANCCLDAICYYYMAKEFQ 284
LE A T + AN LD I +Y+ K+F+
Sbjct: 276 LEAFAAAYKGTRPFASANSVLDPILFYFTQKKFR 309
>gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 111 bits (277), Expect = 9e-25
Identities = 83/274 (30%), Positives = 124/274 (45%), Gaps = 19/274 (6%)
Query: 30 LLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPL- 88
+L GL LN + C + T T +Y NLA+ADL C+LP ++++ P
Sbjct: 36 VLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFG 95
Query: 89 ---CQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAA-AVCAVLWVLV 144
C+L + ++ N + SI +T I+ RY+ + HPL R R+AA VC +W+ V
Sbjct: 96 DFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAV 155
Query: 145 IGSLVARWLL---GIQEG-GFCF------RSTRHNFNSMAFPLLGFYLPLAVVVFCSLKV 194
+ + GIQ C+ +T + MA ++GF LP A ++ C +
Sbjct: 156 TTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLL 215
Query: 195 VTALA-QRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWN---ACAL 250
L Q P + E KAARM F + FLP H+ T LAV C +
Sbjct: 216 ACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTV 275
Query: 251 LETIRRALYITSKLSDANCCLDAICYYYMAKEFQ 284
LE A T + AN LD I +Y+ K+F+
Sbjct: 276 LEAFAAAYKGTRPFASANSVLDPILFYFTQKKFR 309
>gi|47271392 succinate receptor 1 [Homo sapiens]
Length = 334
Score = 111 bits (277), Expect = 9e-25
Identities = 81/277 (29%), Positives = 135/277 (48%), Gaps = 18/277 (6%)
Query: 26 YLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTS- 84
+ G+ V+G+L N++ ++ + ++ W + IY+ NL+V+DL LCTLP ++ S + +
Sbjct: 29 FYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYANGNW 88
Query: 85 --DTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWV 142
LC ++ + N Y SI +T I++DRY+ +++P R L+ A + +WV
Sbjct: 89 IYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWV 148
Query: 143 LVIGSLVARWLL----GIQEGGFC--FRSTRH-NFN---SMAFPLLGFYLPLAVVVFCSL 192
LV L+ L G C F S+ N+N SM LLGF +PL V+ F
Sbjct: 149 LVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYY 208
Query: 193 KVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAV---GWNACA 249
K+ L QR V A K +V +++F V F P HV VR+A W
Sbjct: 209 KIALFLKQR-NRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQ 267
Query: 250 LLETIRRALYI-TSKLSDANCCLDAICYYYMAKEFQE 285
+ + + YI T L+ N ++ + Y+ + F++
Sbjct: 268 CTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRD 304
>gi|4505557 purinergic receptor P2Y1 [Homo sapiens]
Length = 373
Score = 110 bits (274), Expect = 2e-24
Identities = 75/288 (26%), Positives = 140/288 (48%), Gaps = 23/288 (7%)
Query: 29 VLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSD--- 85
++ ++G L NS+A+W+F M+ W+ +YM NLA+AD + TLP ++ + +D
Sbjct: 60 LVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIF 119
Query: 86 -TPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLV 144
+C+L + I+ N Y SI +T I+ RY V +PL++ G + A + ++W++V
Sbjct: 120 GDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIV 179
Query: 145 ---IGSLVARWLLGIQEGG--FCFRSTRHNF------NSMAFPLLGFYLPLAVVVFCSLK 193
I ++ G+++ C+ +T + SM + F +PL +++ C
Sbjct: 180 VVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGL 239
Query: 194 VVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWN-----AC 248
+V AL + D+ + RK+ +V L VF V ++P HV T+ L + C
Sbjct: 240 IVRALIYK---DLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMC 296
Query: 249 ALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAK 296
A + + +T L+ N C+D I Y+ F+ + A +++
Sbjct: 297 AFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASR 344
>gi|4885335 G protein-coupled receptor 4 [Homo sapiens]
Length = 362
Score = 108 bits (271), Expect = 5e-24
Identities = 91/300 (30%), Positives = 138/300 (46%), Gaps = 41/300 (13%)
Query: 2 NGTYNTC---GSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIY 58
N T+ C D +PP++ Y+ V+ V GL N LALW ++QQ E +Y
Sbjct: 3 NHTWEGCHVDSRVDHLFPPSL------YIFVIGV-GLPTNCLALWAAYRQVQQRNELGVY 55
Query: 59 MTNLAVADLCLLCTLP----FVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDR 114
+ NL++ADL +CTLP + LH C+L I+ TN Y+SI+ + I+VDR
Sbjct: 56 LMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDR 115
Query: 115 YVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRST-RHNFNSM 173
Y+AV HPLR LR + A AV +V+W +G+ A FR H F
Sbjct: 116 YLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLF-----HDELFRDRYNHTFCFE 170
Query: 174 AFPL-------------LGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVW 220
FP+ +GF P A+++ ++ A+ T + + K R+
Sbjct: 171 KFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVST---ERQEKAKIKRLAL 227
Query: 221 ANLLVFVVCFLPLHVGLTVRLAV----GWNACALLETIRRALYITSKLSDANCCLDAICY 276
+ + + +VCF P HV L R A+ W+ C E + A + + + NC D I Y
Sbjct: 228 SLIAIVLVCFAPYHVLLLSRSAIYLGRPWD-CGFEERVFSAYHSSLAFTSLNCVADPILY 286
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.138 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,900,101
Number of Sequences: 37866
Number of extensions: 409490
Number of successful extensions: 2545
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 357
Number of HSP's successfully gapped in prelim test: 232
Number of HSP's that attempted gapping in prelim test: 1493
Number of HSP's gapped (non-prelim): 667
length of query: 309
length of database: 18,247,518
effective HSP length: 102
effective length of query: 207
effective length of database: 14,385,186
effective search space: 2977733502
effective search space used: 2977733502
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.