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Search of human proteins with 122937496
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937496 WAS/WASL interacting protein family, member 3
[Homo sapiens]
(483 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 1028 0.0
gi|18959210 WIRE protein [Homo sapiens] 222 5e-58
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 202 7e-52
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 202 7e-52
gi|47132519 Ras association and pleckstrin homology domains 1 is... 158 9e-39
gi|160707881 formin 2 [Homo sapiens] 142 9e-34
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 139 4e-33
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 138 1e-32
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 131 2e-30
gi|163965366 nascent polypeptide-associated complex alpha subuni... 128 1e-29
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 118 1e-26
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 114 2e-25
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 112 6e-25
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 112 6e-25
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 112 6e-25
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 110 3e-24
gi|116284392 mucin 2 precursor [Homo sapiens] 105 9e-23
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 105 1e-22
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 103 3e-22
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 103 3e-22
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 103 3e-22
gi|150417989 cyclin K isoform 1 [Homo sapiens] 103 3e-22
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 101 2e-21
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 100 3e-21
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 98 2e-20
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 98 2e-20
gi|40807452 peroxisome proliferator-activated receptor gamma, co... 97 2e-20
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 97 4e-20
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 97 4e-20
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 97 4e-20
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 1028 bits (2658), Expect = 0.0
Identities = 483/483 (100%), Positives = 483/483 (100%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
Query: 61 KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG 120
KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG
Sbjct: 61 KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG 120
Query: 121 KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP 180
KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP
Sbjct: 121 KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP 180
Query: 181 PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPA 240
PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPA
Sbjct: 181 PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPA 240
Query: 241 SVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYA 300
SVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYA
Sbjct: 241 SVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYA 300
Query: 301 SCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQK 360
SCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQK
Sbjct: 301 SCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQK 360
Query: 361 KRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFE 420
KRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFE
Sbjct: 361 KRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFE 420
Query: 421 SKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPGPWLQAEAVGQSSDDIKGRNSQVTQA 480
SKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPGPWLQAEAVGQSSDDIKGRNSQVTQA
Sbjct: 421 SKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPGPWLQAEAVGQSSDDIKGRNSQVTQA 480
Query: 481 SCL 483
SCL
Sbjct: 481 SCL 483
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 222 bits (566), Expect = 5e-58
Identities = 176/506 (34%), Positives = 224/506 (44%), Gaps = 123/506 (24%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
MP+PPPPPPP PPPPP+ +T+ L R + +GR ALL DI +GT+L+
Sbjct: 1 MPIPPPPPPP---------PGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLK 51
Query: 61 KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRD---- 116
KVT INDRSAP +E KG++ G + GA+ P G LF GG LRP G +D
Sbjct: 52 KVTNINDRSAPILEKPKGSS----GGYGSGGAALQPK-GGLFQGGVLKLRPVGAKDGSEN 106
Query: 117 VAGGKTGQGPGSRAPSPRLPNKTISG-------------PLIP----PASPRLG--NTSE 157
+AG Q P SRA +PR P SG P +P P+ P L NT+
Sbjct: 107 LAGKPALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTS 166
Query: 158 AHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAP 217
+ G ++ + P PPPP PP P P+ SS K P + PL P
Sbjct: 167 STGMKHSS----SAPPPPPPGRRANAPPTPLPMHSS---KAPAYNREKPL---------P 210
Query: 218 PVPCAPPPP----PPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP 273
P P P PP PPP PP P ++ + P PPP P P P
Sbjct: 211 PTPGQRLHPGREGPPAPPPVKPPPSPVNI--------RTGPSGQSLAPPPPPYRQP---P 259
Query: 274 GLKAEPASPAQDA------------QEPPAP----PPPLPPYASCSPRASLPAPPLPGVN 317
G+ P+SP ++ ++ P P PP P AS S ++ P PP
Sbjct: 260 GVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPP 319
Query: 318 SSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPP 377
S PPP PP + GA+ P PP P + HG GK PP
Sbjct: 320 SRGAAPPPPPPVI--------RNGARDAPPPPPP--------YRMHGSEPPSRGK---PP 360
Query: 378 APPARSPTTELSSKSQQATAWTPTQQPGGQLRNGS-------LHIIDDFESKFTFHSVED 430
PP+R+P P P LRNG +DDFESK++FH VED
Sbjct: 361 PPPSRTPA-------------GPPPPPPPPLRNGHRDSITTVRSFLDDFESKYSFHPVED 407
Query: 431 FPPPDEYKPCQKIYPSKIPRSRTPGP 456
FP P+EYK Q+IYPSK R+ P
Sbjct: 408 FPAPEEYKHFQRIYPSKTNRAARGAP 433
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 202 bits (513), Expect = 7e-52
Identities = 167/515 (32%), Positives = 223/515 (43%), Gaps = 103/515 (20%)
Query: 11 LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSA 70
+P PPPP PPPPP+ +T+ +L + + GR+ALL+DI +G +L+K T NDRSA
Sbjct: 1 MPVPPPPA---PPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKK-TVTNDRSA 56
Query: 71 PQIESSKGTNKEGGGSA----------------NTRGASTPPTLGDLFAGGFPVLRPAGQ 114
P ++ KG GGG + G PP LG LF G P LR
Sbjct: 57 PILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTAN 116
Query: 115 RDVAGGKTGQGPGSRAPS-PRLPNKTISGPLIPPASP-RLGNTSEAHGAARTAPPRPNVP 172
RD G GSR P P T + P PP+ P R S H R+ PP P
Sbjct: 117 RDNDSG------GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH---RSGPPEPQRN 167
Query: 173 APPPPTPP--PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP--PPPPP 228
PPP P P +PPP+PS TP P +G+ PPVP P P P P
Sbjct: 168 RMPPPRPDVGSKPDSIPPPVPS-----TPRPIQSSPHNRGS-----PPVPGGPRQPSPGP 217
Query: 229 PPPPTP--------------PPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGY-P 273
PPP P PL +S S++ P L PPP P PP G P
Sbjct: 218 TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP--PPVGNRP 275
Query: 274 GLKAE--PASPAQDAQEPPAPPPPLPPYASCSPRASLPA-----PPLPGVNSSSETPPPL 326
+ E P P Q+ +PP P P P +S +P P PPLP +S ++ P L
Sbjct: 276 SIHREAVPPPPPQN-NKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334
Query: 327 PPKSPSFQA--PPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
P ++ S + PP + ++ P PP P P + GR G PPP P +R+
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGP-----LPPPPPVSRNG 389
Query: 385 TT--------ELSSKS----------------QQATAWTPTQQPGGQLRNG--SLHIIDD 418
+T +L S+S + + P P +RNG D+
Sbjct: 390 STSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDE 449
Query: 419 FESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRT 453
+ES+F FH + D PPP+ Y K YPSK+ R+ +
Sbjct: 450 WESRFYFHPISDLPPPEPYVQTTKSYPSKLARNES 484
Score = 102 bits (255), Expect = 6e-22
Identities = 122/423 (28%), Positives = 153/423 (36%), Gaps = 106/423 (25%)
Query: 2 PVPPPPPP---PLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58
P PP P P+P P G P P PP D S + P + IQ
Sbjct: 140 PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP- 198
Query: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVA 118
++R +P + GG + G + PP FP G R A
Sbjct: 199 -------HNRGSPPVP--------GGPRQPSPGPTPPP---------FP-----GNRGTA 229
Query: 119 --GGKTGQGP-------GSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPP-- 167
GG Q P +R P P P++ + PP P +GN H A PP
Sbjct: 230 LGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKP-PPPPPPVGNRPSIHREAVPPPPPQ 288
Query: 168 --RPNVP----------APPPPTPP--PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLP 213
+P VP APPPP PP P PPPLPP SS +TP + P +L
Sbjct: 289 NNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP--SSSGNDETPRL----PQRNLSLS 342
Query: 214 VVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP 273
PP+P P PPPP+ P PP + P P+PPP PP
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSERPPPPV----------RDPPGRSGPLPPP----PPVSRN 388
Query: 274 GLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSP-- 331
G A PA P LP + S P PPLP S+ PPP PP +
Sbjct: 389 G-STSRALPA---------TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIR 438
Query: 332 -SFQAPPQKAGAQA---------LPAPPAP----PGSQPFLQKKRHGRPGAGGGKLNPPP 377
FQ P + ++ LP PP P S P + R G+ + PP
Sbjct: 439 NGFQDSPCEDEWESRFYFHPISDLP-PPEPYVQTTKSYPSKLARNESRSGSNRRERGAPP 497
Query: 378 APP 380
PP
Sbjct: 498 LPP 500
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 202 bits (513), Expect = 7e-52
Identities = 167/515 (32%), Positives = 223/515 (43%), Gaps = 103/515 (20%)
Query: 11 LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSA 70
+P PPPP PPPPP+ +T+ +L + + GR+ALL+DI +G +L+K T NDRSA
Sbjct: 1 MPVPPPPA---PPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKK-TVTNDRSA 56
Query: 71 PQIESSKGTNKEGGGSA----------------NTRGASTPPTLGDLFAGGFPVLRPAGQ 114
P ++ KG GGG + G PP LG LF G P LR
Sbjct: 57 PILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTAN 116
Query: 115 RDVAGGKTGQGPGSRAPS-PRLPNKTISGPLIPPASP-RLGNTSEAHGAARTAPPRPNVP 172
RD G GSR P P T + P PP+ P R S H R+ PP P
Sbjct: 117 RDNDSG------GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH---RSGPPEPQRN 167
Query: 173 APPPPTPP--PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP--PPPPP 228
PPP P P +PPP+PS TP P +G+ PPVP P P P P
Sbjct: 168 RMPPPRPDVGSKPDSIPPPVPS-----TPRPIQSSPHNRGS-----PPVPGGPRQPSPGP 217
Query: 229 PPPPTP--------------PPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGY-P 273
PPP P PL +S S++ P L PPP P PP G P
Sbjct: 218 TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP--PPVGNRP 275
Query: 274 GLKAE--PASPAQDAQEPPAPPPPLPPYASCSPRASLPA-----PPLPGVNSSSETPPPL 326
+ E P P Q+ +PP P P P +S +P P PPLP +S ++ P L
Sbjct: 276 SIHREAVPPPPPQN-NKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334
Query: 327 PPKSPSFQA--PPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
P ++ S + PP + ++ P PP P P + GR G PPP P +R+
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGP-----LPPPPPVSRNG 389
Query: 385 TT--------ELSSKS----------------QQATAWTPTQQPGGQLRNG--SLHIIDD 418
+T +L S+S + + P P +RNG D+
Sbjct: 390 STSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDE 449
Query: 419 FESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRT 453
+ES+F FH + D PPP+ Y K YPSK+ R+ +
Sbjct: 450 WESRFYFHPISDLPPPEPYVQTTKSYPSKLARNES 484
Score = 102 bits (255), Expect = 6e-22
Identities = 122/423 (28%), Positives = 153/423 (36%), Gaps = 106/423 (25%)
Query: 2 PVPPPPPP---PLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58
P PP P P+P P G P P PP D S + P + IQ
Sbjct: 140 PFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP- 198
Query: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVA 118
++R +P + GG + G + PP FP G R A
Sbjct: 199 -------HNRGSPPVP--------GGPRQPSPGPTPPP---------FP-----GNRGTA 229
Query: 119 --GGKTGQGP-------GSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPP-- 167
GG Q P +R P P P++ + PP P +GN H A PP
Sbjct: 230 LGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKP-PPPPPPVGNRPSIHREAVPPPPPQ 288
Query: 168 --RPNVP----------APPPPTPP--PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLP 213
+P VP APPPP PP P PPPLPP SS +TP + P +L
Sbjct: 289 NNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP--SSSGNDETPRL----PQRNLSLS 342
Query: 214 VVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP 273
PP+P P PPPP+ P PP + P P+PPP PP
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSERPPPPV----------RDPPGRSGPLPPP----PPVSRN 388
Query: 274 GLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSP-- 331
G A PA P LP + S P PPLP S+ PPP PP +
Sbjct: 389 G-STSRALPA---------TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIR 438
Query: 332 -SFQAPPQKAGAQA---------LPAPPAP----PGSQPFLQKKRHGRPGAGGGKLNPPP 377
FQ P + ++ LP PP P S P + R G+ + PP
Sbjct: 439 NGFQDSPCEDEWESRFYFHPISDLP-PPEPYVQTTKSYPSKLARNESRSGSNRRERGAPP 497
Query: 378 APP 380
PP
Sbjct: 498 LPP 500
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 158 bits (400), Expect = 9e-39
Identities = 148/498 (29%), Positives = 193/498 (38%), Gaps = 137/498 (27%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
P PP PPPP PPPPPP PPPPPP P S S A P + TRL+
Sbjct: 624 PSPPLPPPPPPPPPPP---PPPPPPPPPLPSQSAPSAGSAAP-----MFVKYSTITRLQN 675
Query: 62 VTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGK 121
+Q ++ PPT PV++
Sbjct: 676 ASQ-----------------------HSGALFKPPTP--------PVMQ----------- 693
Query: 122 TGQGPGSRAPSPRL---PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPP-- 176
S++ P++ PN + P PP P G+ A AP P APPP
Sbjct: 694 ------SQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPL 747
Query: 177 ------------PTPPPPPPPLPPPLPSSSPIKTPLVSPPGPL-TKGNLPVV---APPVP 220
P PPPPPP+P PLP +P K PLV+ P P TK PVV APP P
Sbjct: 748 KIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK-PLVTIPAPTSTKTVAPVVTQAAPPTP 806
Query: 221 CAPPPPP-----------PPPPPTPP-PLPPASVLSDKAVKPQLAPLHLPPIPPPLPLL- 267
P PP PP PPTPP P+PP ++ ++ + P L P+P + +
Sbjct: 807 TPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866
Query: 268 ----PPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETP 323
PP P ++++P P P P PP P+ + P+P S + P
Sbjct: 867 SQFPPPPTPPAMESQPLKPV-----PANVAPQSPPAVKAKPKWQPSSIPVP----SPDFP 917
Query: 324 PPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQK-----KRHGRPGAGGGKLNPPPA 378
PP PP+S S PP P PP PP + P K K+ + + GGK PPP
Sbjct: 918 PP-PPES-SLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGK-KPPPT 974
Query: 379 PPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYK 438
P S S KS ++P +D SKFT PP +
Sbjct: 975 PQRNS-----SIKSSSGAEHPEPKRPS----------VDSLVSKFT-------PPAESGS 1012
Query: 439 PCQKIYPSKIPRSRTPGP 456
P ++ P P + P P
Sbjct: 1013 PSKETLP---PPAAPPKP 1027
Score = 100 bits (250), Expect = 2e-21
Identities = 131/484 (27%), Positives = 161/484 (33%), Gaps = 123/484 (25%)
Query: 1 MPVPPPPPPP---------LPPPP-----PPLGAPPPP-------------PPSAPPVST 33
+P PPPPPPP L P P P APPPP PP+ PP
Sbjct: 709 VPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP 768
Query: 34 DTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGAS 93
+ L P+ L I T + V + ++AP
Sbjct: 769 IPAPL---PPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP-------------------TP 806
Query: 94 TPPTLGDLFAGGFPV--LRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPR 151
TPP FP + P+ P P P LP K S PP SP
Sbjct: 807 TPPVPPAKKQPAFPASYIPPSPPT----------PPVPVPPPTLP-KQQSFCAKPPPSPL 855
Query: 152 LGNTSEAHGAARTAPPRPNVPA----PPPPTPPPPPPPLPPPL-------PSSSPIKTPL 200
S A PP P PA P P P P PP + PSS P+ +P
Sbjct: 856 SPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPD 915
Query: 201 VSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPI 260
PP P + P PP P P PPPPPPPT P P S K +P P
Sbjct: 916 FPPPPPESSLVFP---PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPP 972
Query: 261 PPP-----LPLLPPCGYPGLK--------------AEPASPAQDAQEPPAPPPPLP---- 297
P P + +P K AE SP+++ PPA PP
Sbjct: 973 PTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNL 1032
Query: 298 -----PYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPP--- 349
P S AP L G S P PP F PP + LP PP
Sbjct: 1033 SGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPET---ELPLPPIEI 1089
Query: 350 --------APPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSK--SQQATAWT 399
+P + Q ++ + K PPP P R+ +T L+ S+Q T T
Sbjct: 1090 PAVFSGNTSPKVAVVNPQPQQWSKMSV---KKAPPPTRPKRNDSTRLTQAEISEQPTMAT 1146
Query: 400 PTQQ 403
Q
Sbjct: 1147 VVPQ 1150
Score = 98.6 bits (244), Expect = 1e-20
Identities = 99/380 (26%), Positives = 134/380 (35%), Gaps = 87/380 (22%)
Query: 121 KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP 180
++ G P+ + +++I + A R E+ A + RP PP +P
Sbjct: 553 QSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQ 612
Query: 181 PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPA 240
P + P +S P SPP PP P PPPPPPPPPP PPPLP
Sbjct: 613 PK---IVTPYTASQP------SPP-----------LPPPPPPPPPPPPPPPPPPPPLPSQ 652
Query: 241 S-------------------------------------VLSDKAVKPQL--APLHLPPIP 261
S V+ ++VKPQ+ P + P P
Sbjct: 653 SAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPP 712
Query: 262 PPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPY-----ASCSPRASLPAPPLPGV 316
PP P P G + +PA A + APPPPL + +P P PP+P
Sbjct: 713 PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAP 772
Query: 317 NSSSETPPPL----PPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGK 372
P PL P S AP A P PP PP + +P
Sbjct: 773 LPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK---------QPAFPASY 823
Query: 373 LNP-PPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDF 431
+ P PP PP P L QQ+ P P + + I F T
Sbjct: 824 IPPSPPTPPVPVPPPTL--PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPT------- 874
Query: 432 PPPDEYKPCQKIYPSKIPRS 451
PP E +P + + + P+S
Sbjct: 875 PPAMESQPLKPVPANVAPQS 894
Score = 88.2 bits (217), Expect = 2e-17
Identities = 147/572 (25%), Positives = 174/572 (30%), Gaps = 218/572 (38%)
Query: 3 VPPPPPPPLPPPP----------------PPLGAPPPP-------------PPSAPPVST 33
VPPPPPPP PP P P APPPP PP+ PP
Sbjct: 709 VPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP 768
Query: 34 DTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGAS 93
+ L P+ L I T + V + ++AP
Sbjct: 769 IPAPL---PPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP-------------------TP 806
Query: 94 TPPTLGDLFAGGFPV--LRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPR 151
TPP FP + P+ P P P LP K S PP SP
Sbjct: 807 TPPVPPAKKQPAFPASYIPPSPPT----------PPVPVPPPTLP-KQQSFCAKPPPSPL 855
Query: 152 LGNTSEAHGAARTAPPRPNVPA----PPPPTPPPPPPPLPPPL-------PSSSPIKTPL 200
S A PP P PA P P P P PP + PSS P+ +P
Sbjct: 856 SPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPD 915
Query: 201 VSPPGPLTKGNLPVVAP-PVPCAPPPPPPP-------------------------PPPTP 234
PP P + P P PVP PPPPPP PPPTP
Sbjct: 916 FPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTP 975
Query: 235 ----------------PPLPPASVLSDKAVKPQ---------LAPLHLPPIPPPLPL--- 266
P P L K P L P PP P L L
Sbjct: 976 QRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGV 1035
Query: 267 -LPPCGYPGLKAEPA---------------SPAQDAQEPPAPPP---PLPPY-------A 300
LP G + A SP D+ PP PP PLPP
Sbjct: 1036 NLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSG 1095
Query: 301 SCSPRASL--PAPPLPGVNSSSETPPPLPPKS------PSFQAPPQKAGAQALPAPPAPP 352
+ SP+ ++ P P S + PPP PK + Q A +P P P
Sbjct: 1096 NTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155
Query: 353 GS----QP--------FLQKK---RHG--------------------------------R 365
S QP LQ+K RHG +
Sbjct: 1156 KSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQK 1215
Query: 366 PGAGGGKLN--------PPPAPPARSPTTELS 389
G GG ++ PPPAPP R T+LS
Sbjct: 1216 AGYGGSHISGYATLRRGPPPAPPKRDQNTKLS 1247
Score = 70.5 bits (171), Expect = 3e-12
Identities = 91/362 (25%), Positives = 126/362 (34%), Gaps = 64/362 (17%)
Query: 1 MPVPPPPPPPLPP------PPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQ 54
+PVP P PP PP PPPP P PPP PP ++ T D G
Sbjct: 909 IPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPT-----PDKSG--------S 955
Query: 55 QGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQ 114
G + K + + P + K G+ + P++ L + P PA
Sbjct: 956 PGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPE--PKRPSVDSLVSKFTP---PA-- 1008
Query: 115 RDVAGGKTGQGPGSRAPSPRLPNK----TISGPLIPPASPRLGNTSEAHG-AARTAPPRP 169
++G P P P K +SG +P + +++A + R
Sbjct: 1009 ------ESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVV 1062
Query: 170 NVPAPPPPTP-PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAP-PVPCAPPPPP 227
P+PP + PPPPP PLP PI+ P V T + VV P P +
Sbjct: 1063 EFPSPPSDSDFPPPPPETELPLP---PIEIPAVFSGN--TSPKVAVVNPQPQQWSKMSVK 1117
Query: 228 PPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAE--------- 278
PPPT P ++ L+ + Q + P P P PG A+
Sbjct: 1118 KAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKS 1177
Query: 279 -----PASPAQDAQEPPAP------PPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLP 327
S EP A PPP P S +A + G + PPP P
Sbjct: 1178 ITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAP 1237
Query: 328 PK 329
PK
Sbjct: 1238 PK 1239
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 142 bits (357), Expect = 9e-34
Identities = 134/413 (32%), Positives = 151/413 (36%), Gaps = 96/413 (23%)
Query: 3 VPPPPP----PPLPPPPPPL-GAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
+P PPP LPPPPPPL GA PPPP P G L G
Sbjct: 896 IPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLP---------------GAGILPLPPLPGA 940
Query: 58 RLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117
+ + + P G G PP L G P P
Sbjct: 941 GIPPPPPLPGAAIPPPPPLPGA-----------GIPLPPPLP---GAGIPPPPPL----- 981
Query: 118 AGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPP 177
PG+ P P + G IPP P G PP P PPPP
Sbjct: 982 --------PGAGIPPP----PPLPGAGIPPPPPLPG------AGIPPPPPLPGAGIPPPP 1023
Query: 178 TPP----PPPPPLPPP-LPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP- 231
P PPPPPLP +P P+ + PP PL +P PP+P A PPPPP P
Sbjct: 1024 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPG 1082
Query: 232 ---PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLP---LLPPCGYPGLKAEPASPAQD 285
P PPPLP A + P L + +PP PPPLP + PP PG P P
Sbjct: 1083 AGIPPPPPLPGAGI----PPPPPLPGVGIPP-PPPLPGAGIPPPPPLPGAGIPPPPPLPG 1137
Query: 286 AQEPPAPP------PPLPPYASCS-------PRASL-PAPPLPGVNSSSETPPPLPPKSP 331
A PP PP PP PP P A + P PPLPGV PPP P
Sbjct: 1138 AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG----IPPPPPLPGV 1193
Query: 332 SFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
PP GA P PP P P PG G + PPP P P
Sbjct: 1194 GIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTG---IPPPPLLPVSGP 1243
Score = 137 bits (346), Expect = 2e-32
Identities = 128/382 (33%), Positives = 147/382 (38%), Gaps = 72/382 (18%)
Query: 1 MPVPP------PPPPPLP----PPPPPL---GAP-PPPPPSA---PPVSTDTSSLRRADP 43
+P+PP PPPPPLP PPPPPL G P PPP P A PP + + P
Sbjct: 932 LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPP 991
Query: 44 KGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFA 103
G + + P G G PP L
Sbjct: 992 ----------LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---G 1038
Query: 104 GGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAAR 163
G P P + G G P P + G IPP P G
Sbjct: 1039 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPP------LPGAGIPPPPPLPG------AGIP 1086
Query: 164 TAPPRPNVPAPPPPTPP----PPPPPLP-PPLPSSSPIKTPLVSPPGPLTKGNLPVVAPP 218
PP P PPPP P PPPPPLP +P P+ + PP PL +P PP
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPP 1145
Query: 219 VPCAPPPPPPPPP----PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLP---LLPPCG 271
+P PPPPP P P PPPLP A + P L + +PP PPPLP + PP
Sbjct: 1146 LPRVGIPPPPPLPGAGIPPPPPLPGAGI----PPPPPLPGVGIPP-PPPLPGVGIPPPPP 1200
Query: 272 YPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSP 331
PG P P PPAP PPLPP P +P PPL V+ PP LP
Sbjct: 1201 LPGAGIPPPPPLPGMGIPPAPAPPLPP-----PGTGIPPPPLLPVSG----PPLLPQVGS 1251
Query: 332 SFQAPPQKAGAQALPAPPAPPG 353
S PQ G LP PP P G
Sbjct: 1252 STLPTPQVCG--FLP-PPLPSG 1270
Score = 126 bits (317), Expect = 4e-29
Identities = 111/310 (35%), Positives = 124/310 (40%), Gaps = 70/310 (22%)
Query: 131 PSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPA----PPPPTP------- 179
P P LP T+ P +P S + G PP P +P PPPP P
Sbjct: 879 PPPPLPGMTV--PTLP--STAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPL 934
Query: 180 --------PPPPP------PLPPPLPSSS-PIKTPL----VSPPGPLTKGNLPVVAPPVP 220
PPPPP P PPPLP + P+ PL + PP PL +P PP+P
Sbjct: 935 PPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPP-PPPLP 993
Query: 221 CAP-PPPPP------PPP--------PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLP 265
A PPPPP PPP P PPPLP A + P L +PP PPPLP
Sbjct: 994 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI----PPPPPLPGAGIPP-PPPLP 1048
Query: 266 ---LLPPCGYPGLKAEPASPAQDAQEPPAPPPP---LPPYASCSPRASLPAPPLPGVNSS 319
+ PP PG P P A PP PP P +PP P PPLPGV
Sbjct: 1049 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG-- 1106
Query: 320 SETPPPLPPKSPSFQAPPQKAGAQALPAPPAP-PGSQPFLQKKRHGRPG----AGGGKLN 374
PPP P PP GA P PP P G P R G P G G
Sbjct: 1107 --IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPP 1164
Query: 375 PPPAPPARSP 384
PPP P A P
Sbjct: 1165 PPPLPGAGIP 1174
Score = 124 bits (311), Expect = 2e-28
Identities = 99/289 (34%), Positives = 112/289 (38%), Gaps = 66/289 (22%)
Query: 146 PPASPRLGNTSEAHGAARTAPPRPNVPA-----------------------PPPPTP--- 179
PP P ++S G PP P +P PPPP P
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917
Query: 180 --PPPPPPLP-------PPLPSSS-----PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPP 225
PPPPPLP PPLP + P+ + PP PL +P + PP+P A P
Sbjct: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIP-LPPPLPGAGIP 976
Query: 226 PPPPPP----PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLP---LLPPCGYPGLKAE 278
PPPP P P PPPLP A + P L +PP PPPLP + PP PG
Sbjct: 977 PPPPLPGAGIPPPPPLPGAGI----PPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIP 1031
Query: 279 PASPAQDAQEPPAPPPP---LPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQA 335
P P A PP PP P +PP P PPLPG PPP P
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIPP 1087
Query: 336 PPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
PP GA P PP P P P G G PPP P A P
Sbjct: 1088 PPPLPGAGIPPPPPLPGVGIP------PPPPLPGAGIPPPPPLPGAGIP 1130
Score = 119 bits (299), Expect = 5e-27
Identities = 95/274 (34%), Positives = 109/274 (39%), Gaps = 59/274 (21%)
Query: 155 TSEAHGAARTAPPRPNVPAPPP-------------PTPPPPPPPLP----PPLPSSSPIK 197
TS H + N+P+PPP PPPPPPLP P LPS++ +
Sbjct: 839 TSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQ 898
Query: 198 TP-------LVSPPGPLTKGNLP----------VVAPPVPCAPPPPPPPPP----PTPPP 236
P L PP PL +P + PP+P A PPPPP P P PPP
Sbjct: 899 PPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPP 958
Query: 237 LPPASVLSDKAVKPQLAPLHLPPIPPPLP---LLPPCGYPGLKAEPASPAQDAQEPPAPP 293
LP A + + P L +PP PPPLP + PP PG P P A PP PP
Sbjct: 959 LPGAGI----PLPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1013
Query: 294 PP---LPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPA 350
P +PP P PPLPG PPP P PP GA P PP
Sbjct: 1014 LPGAGIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069
Query: 351 PPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
P P P G G PPP P A P
Sbjct: 1070 PGAGIP------PPPPLPGAGIPPPPPLPGAGIP 1097
Score = 97.1 bits (240), Expect = 3e-20
Identities = 83/243 (34%), Positives = 93/243 (38%), Gaps = 58/243 (23%)
Query: 179 PPPPP----------PPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPP-VPCA----- 222
PPPPP P PP S+ +T K + + +PP +PC
Sbjct: 810 PPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSS 869
Query: 223 -------PPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLH----LPPIPPPLP---LLP 268
PPPPPP P T P LP ++ PQ PL LPP PPPLP + P
Sbjct: 870 MPGLGMVPPPPPPLPGMTVPTLPSTAI-------PQPPPLQGTEMLPPPPPPLPGAGIPP 922
Query: 269 PCGYPGLKAEPASPAQDAQEPPAPP------PPLPPYASCSPRASLP-APPLPGVNSSSE 321
P PG P P A PP PP PP PP P A +P PPLPG
Sbjct: 923 PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPL----PGAGIPLPPPLPGAG---- 974
Query: 322 TPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPA 381
PPP P PP GA P PP P P P G G PPP P A
Sbjct: 975 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP------PPPPLPGAGIPPPPPLPGA 1028
Query: 382 RSP 384
P
Sbjct: 1029 GIP 1031
Score = 91.3 bits (225), Expect = 2e-18
Identities = 101/317 (31%), Positives = 117/317 (36%), Gaps = 47/317 (14%)
Query: 2 PVPP------PPPPPLP----PPPPPL---GAPPPPP-PSA---PPVSTDTSSLRRADP- 43
P PP PPPPPLP PPPPPL G PPPPP P A PP + + P
Sbjct: 988 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047
Query: 44 KGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFA 103
G G + + P G G PP L +
Sbjct: 1048 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV-- 1105
Query: 104 GGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPL------IPPASPRLGNTSE 157
G P P + G G P P LP I P IPP P G
Sbjct: 1106 -GIPPPPPLPGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPRVGIPPPPPLPG---- 1159
Query: 158 AHGAARTAPPRPNVPAPPPPTPP----PPPPPLP-PPLPSSSPIKTPLVSPPGPLT-KGN 211
PP P PPPP P PPPPPLP +P P+ + PP PL G
Sbjct: 1160 --AGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGI 1217
Query: 212 LPVVAPPVPCAPP----PPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLL 267
P APP+P PP PPPP P + PPL P V S PQ+ PP+P L L
Sbjct: 1218 PPAPAPPLP--PPGTGIPPPPLLPVSGPPLLP-QVGSSTLPTPQVCGFLPPPLPSGLFGL 1274
Query: 268 PPCGYPGLKAEPASPAQ 284
G + +P P +
Sbjct: 1275 GMNQDKGSRKQPIEPCR 1291
Score = 41.2 bits (95), Expect = 0.002
Identities = 71/325 (21%), Positives = 99/325 (30%), Gaps = 51/325 (15%)
Query: 153 GNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNL 212
G EA G+ T + P P P PP P P+
Sbjct: 258 GGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSE-------------- 303
Query: 213 PVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKP------------QLAPLHLPPI 260
AP +P A P P T P P A + A P + A P
Sbjct: 304 ---APSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRG 360
Query: 261 PPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP-PPPLPPYASCSPRASLPAPPLPGVNSS 319
P P G + P ++AQ P AP LP + S R P P +
Sbjct: 361 SPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIK 420
Query: 320 SETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQK-----KRHGRPG--AGGGK 372
+ T P Q+P Q + P P GS+ L K+H G A G
Sbjct: 421 TTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLS 480
Query: 373 LNPPPAPPARSPTTELSSKSQQATAWTPTQQPGG------QLRNGSLHIIDDFESKFT-- 424
+ + T + + + GG +G+ D F++ FT
Sbjct: 481 RSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAADGFQNVFTGR 540
Query: 425 ------FHSVEDFPPPDEYKPCQKI 443
F E+ PP + K C +I
Sbjct: 541 TLLEKLFSQQENGPPEEAEKFCSRI 565
Score = 35.8 bits (81), Expect = 0.089
Identities = 35/122 (28%), Positives = 44/122 (36%), Gaps = 14/122 (11%)
Query: 243 LSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPP--------- 293
L + + QL P PP P + GL P+ A E P P
Sbjct: 217 LQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSAL 276
Query: 294 PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
LP + PR PP PG SE P LP P+ + P + A P P A PG
Sbjct: 277 SDLPESLAAEPREP-QQPPSPGGLPVSEA-PSLPAAQPAAKDSP---SSTAFPFPEAGPG 331
Query: 354 SQ 355
+
Sbjct: 332 EE 333
Score = 33.5 bits (75), Expect = 0.44
Identities = 42/160 (26%), Positives = 63/160 (39%), Gaps = 22/160 (13%)
Query: 284 QDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343
Q A+EP APP + P P A L G++ L P + +AP Q
Sbjct: 227 QGAEEPAAPPTAVSP----QPGAFL------GLDRFL-----LGPSGGAGEAPGSPDTEQ 271
Query: 344 ALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWT-PTQ 402
AL A P S ++ P GG ++ P+ PA P + S +TA+ P
Sbjct: 272 ALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPA---AKDSPSSTAFPFPEA 328
Query: 403 QPGGQLRNGSLHIIDDFESKFTFHSVEDFP---PPDEYKP 439
PG + + D + + + ED P P +E+ P
Sbjct: 329 GPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAP 368
Score = 31.6 bits (70), Expect = 1.7
Identities = 42/145 (28%), Positives = 51/145 (35%), Gaps = 17/145 (11%)
Query: 227 PPPPPPTPPPLPPASVLSDK-AVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQD 285
P PP P P A + D+ + P P P L L P S A +
Sbjct: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALS-----ALSDLPESLAAE 286
Query: 286 AQEPPAPPPP--LPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343
+EP PP P LP S SLPA +S S T P P P +A AGA
Sbjct: 287 PREPQQPPSPGGLP----VSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEA----AGAP 338
Query: 344 ALPAPPA-PPGSQPFLQKKRHGRPG 367
A G + + G PG
Sbjct: 339 VRGAGDTDEEGEEDAFEDAPRGSPG 363
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 139 bits (351), Expect = 4e-33
Identities = 137/451 (30%), Positives = 171/451 (37%), Gaps = 75/451 (16%)
Query: 1 MPVPPPPPPPLPPP---PPPLGAPPP----PPPSAPPVSTDTSSLRRADPKGRSALLADI 53
+P PP PP PP PP+ APP PP P T S P S+L A
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416
Query: 54 QQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAG 113
G+ + T +P+ + T+ +R ASTPP L A P+ PA
Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSP-------SRPASTPPDSPPLQA---PLSLPAS 466
Query: 114 QRDVAGGKTGQGPGS--------------RAPSPRLPNKTISGPLIPPASPRLGNTSEAH 159
P S + SP+ P ++ P + S + +
Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526
Query: 160 GAARTAPPRPNVP--APPP--------PTPPPPPPPLPPPLPSSSPIKTPLVSPP--GPL 207
A+ T PP N+P APPP TP PP P P P +P +PL +PP P
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP-PSPLTTPPPETPS 585
Query: 208 TKGNLPVVAPPVPCAP-----PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPP 262
+ P APP +P P PP P TPPP P + L PL PP PP
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL--------ALPPLQAPPSPP 637
Query: 263 PLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLP------------- 309
P L P P +A A Q P +PPP P A SP AS P
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697
Query: 310 ---APPLPGVNSSSETPPPLPPKSPSFQAPPQKAG--AQALPAPPAPPGSQPFLQKKRHG 364
APPL S +PP P +P QAPP A Q P+PPA P P
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 365 RPGAGGGKLNPPPAPPARSPTTELSSKSQQA 395
P L PP+PPA P + L+ QA
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788
Score = 138 bits (347), Expect = 1e-32
Identities = 158/513 (30%), Positives = 207/513 (40%), Gaps = 82/513 (15%)
Query: 5 PPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQ 64
P P PP PPL AP P S PP+ T S P + +Q + L +
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPAS-PPLQTSLSPA--VSPLSSPLTIHPLQALSSLASHSP 500
Query: 65 INDRSAPQIESSKGTNKEGGGSANTRGAS-TPPTLGDLFAGGFPVLRPAGQRDVAGGKTG 123
S+ + + + S T AS T P L +L P L P + + T
Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL-----PSLAPPPLQTASAPLTT 555
Query: 124 ---QGPGSRAPSP-RLPNKTISGPLIPPASPRLGNTSEAHGA-ARTAPPRPNVPAPPPP- 177
+ P AP P + P ++ P PP +P T A +PP +P+PP
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTP--PPETPSSIATPPPQAPPALASPPLQGLPSPPLSP 613
Query: 178 --TPPPPPPP---LPP----PLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPP 228
TPPP PP LPP P P +SP +PL +P P L V P +PPP PP
Sbjct: 614 LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATP-SPQAPNALAVHLLQAPFSPPPSPP 672
Query: 229 PP----PPTPPPLPPASVLSDKAVKPQLA--PLHLPPIPPPLPLLPPCGYPGLKAEPASP 282
PP PP+ P++ +A P LA PL +PP PP P + P P +A P
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQA-PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
Query: 283 AQDAQEPPAPP--PPLPPYASCSPRAS--LPAPPLPGVNSSSETPPPLPPKSPSFQAPPQ 338
A Q PP+PP PP+ P A+ PR L APPL S + P P P QAPP
Sbjct: 732 APPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA 791
Query: 339 KA--GAQALPAPPAP-PGSQPFLQKKR-----------HGRPGAGGGKLNPPPAPPARSP 384
A QALP+PPA PG PF P L PP+PPA SP
Sbjct: 792 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA-SP 850
Query: 385 TTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIY 444
T QA PT P + L + ++ PPP
Sbjct: 851 TL-------QAPRRPPTPGPDTSVSGPRLTL-----------ALAPGPPPP--------- 883
Query: 445 PSKIPRSRTPGPWLQAEAVGQSS--DDIKGRNS 475
PS+ P S GP L + +S ++++G +S
Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916
Score = 124 bits (311), Expect = 2e-28
Identities = 128/421 (30%), Positives = 156/421 (37%), Gaps = 97/421 (23%)
Query: 1 MPVPPPPPPPLPPP--PPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58
+P PP P PPP PP L PP P +PP S S L P+ +AL + Q
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ--- 662
Query: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVA 118
A +PP P + P+
Sbjct: 663 ----------------------------APFSPPPSPPVQAPFSPPASPPVSPSAT---- 690
Query: 119 GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAA---RTAPP---RPNVP 172
P S+AP P L + P PPASP + ++ A APP P+ P
Sbjct: 691 -------PPSQAP-PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP 742
Query: 173 APPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPP 232
A PP +P PPP PPL ++ P++ P SPP L P P A PPP PP
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVP-PSPPASL---------PMSPLAKPPPQAPPAL 792
Query: 233 TPPPL-----PPASVLSDKAVKPQLAPLHLPPIPPPLPLLPP-CGYPGLKAEPASPAQDA 286
PPL PPAS P A L + P+ P P PP P L+ P+ PA
Sbjct: 793 ATPPLQALPSPPASFPGQAPFSPS-ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851
Query: 287 -QEPPAPPPPLPPYASCSPRASL---PAPPLPGVNSSSET--PPPLPPKSPSFQAPPQ-- 338
Q P PP P P + PR +L P PP P S S T P L S S + P+
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 911
Query: 339 -------KAGAQALPAP--------PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARS 383
+ GA A P P PA P G PGA P P PPA
Sbjct: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA------PLPWPPATG 965
Query: 384 P 384
P
Sbjct: 966 P 966
Score = 109 bits (273), Expect = 5e-24
Identities = 140/514 (27%), Positives = 179/514 (34%), Gaps = 122/514 (23%)
Query: 6 PPPPPLPPPPPPLGAPPPPPPSAPPVST-DTSSLRRADPKGRSALLADIQQGTRLRKVTQ 64
P P P P PP P SA ST + S R P L + T
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS-SSATP 248
Query: 65 IND--RSAPQIESSKGTNKEGGGSANTRG----ASTPPTLGDLFAGGFPVLRPAGQRDVA 118
++ RS P S++GT + + + A PP + P L P +A
Sbjct: 249 LSSPARSGP---SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
Query: 119 GGKTGQGPGSRA-PSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPR----PNVPA 173
T G++A P P N P P SP L + +APP P+ PA
Sbjct: 306 ---TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362
Query: 174 PPPPTPPP----PPPPLPPPLPSSSPIKTP-------LVSPPGPLTKGNLP--------- 213
PP PP PP PP L + PI+ P L +PP PL +L
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422
Query: 214 ------------------VVAPPVPCAPPPPPPP--PPPTPPPLPPASVLSDKAVKPQLA 253
+ +P P + PP PP P + P PP AV P +
Sbjct: 423 LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS 482
Query: 254 PLHLPP-------------------IPPPLPLLPPCGYPGLKAEPASPAQDAQE--PPAP 292
PL + P I PPL P L+ PAS E P
Sbjct: 483 PLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542
Query: 293 PPPL--------------PPYASCSPRASLPAP---PLPGVNSSSETPP----------- 324
PPPL PP + P + P+P P P SS TPP
Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602
Query: 325 ----PLPPKSPSFQAPPQKAGAQALP---APPAPPGSQPF--LQKKRHGRPGAGGGKL-- 373
P PP SP PPQ ALP APP+PP S P L P A L
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 662
Query: 374 ---NPPPAPPARSPTTELSSKSQQATAWTPTQQP 404
+PPP+PP ++P + +S +A P+Q P
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696
Score = 103 bits (256), Expect = 5e-22
Identities = 143/461 (31%), Positives = 165/461 (35%), Gaps = 103/461 (22%)
Query: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVT 63
P P L P PP G+P PPPP P L A GR LA+ G +
Sbjct: 17 PAARAPGLLTPRPP-GSPRPPPPVTPAA---LRVLGAAGAVGRKP-LAERAGGIGGATIP 71
Query: 64 QINDRSAPQIESSKGTNKEGGGS---ANTRGASTPP--------------TLGDLFAG-- 104
+ R+ P S GT+ S A+ RG PP G G
Sbjct: 72 ESAPRAGP--TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 105 GFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAART 164
G LR + + VA GK + P A S T SGP SP + S A G
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDT-SGPTPGTPSPAMARRSRAAG-TEV 187
Query: 165 APPRPNVPA-PPPPTPPP-------------PPPPLPPPLPSS------------SPIKT 198
PRP A P PPT P P P PS+ S T
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 199 PLVSP--PGPLTKGNLPVVAPPVPCAPPPPPP-------PPPPTPPPLPPASVLSDKAVK 249
PL SP GP +G P P P P P PP TPP K
Sbjct: 248 PLSSPARSGPSARG-----TPRAPAHPSQPKPKGLQALRPPQVTPP---------RKDAA 293
Query: 250 PQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEP-PAPPPPLPPYASCSPRASL 308
P L PL P+ P P G KA P P +A P PA PP PP A+ P
Sbjct: 294 PALGPLSSSPLATPSP-------SGTKARPVPPPDNAATPLPATLPPSPPLATPLPL--- 343
Query: 309 PAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQ--PFLQKKRHGRP 366
APP P S +T P PP +P QAPP + P APP Q P +Q
Sbjct: 344 -APPSPSAPPSLQTLPS-PPATPPSQAPP----SMTTPPMQAPPSLQTIPPIQVPH---- 393
Query: 367 GAGGGKLNPPPAPPARS---PTTELSSKSQQATAWTPTQQP 404
L PP+P A S TT L S + QAT T P
Sbjct: 394 SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434
Score = 90.9 bits (224), Expect = 2e-18
Identities = 112/408 (27%), Positives = 145/408 (35%), Gaps = 67/408 (16%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
P PP PP P P S+P ++ T+ R P G+ L ++ K
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT---RPGPLGQKGLRISAEETVARGK 146
Query: 62 VTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGK 121
T+ RSA S G ++ G T G +P A G V P
Sbjct: 147 ATEAPKRSA----LSAGARRDTSGP--TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP 200
Query: 122 TGQGP----------GSRAPSPRLPNK-TISGPLIPPASPRLGNTSEAHGA-ARTAPPRP 169
+GP + PSP + + G L PAS L +++ + AR+ P
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 260
Query: 170 NVP-APPPPTPPPP-------PPPLPPPLPSSSPIKTPLVSPP----GPLTKGNLPVVAP 217
P AP P+ P P PP + PP ++P PL S P P PV P
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP 320
Query: 218 PVPCAPPP---PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPG 274
P P PP PP TP PL P S + P L L PP PP P P
Sbjct: 321 DNAATPLPATLPPSPPLATPLPLAPPS----PSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
Query: 275 LKAEPASPAQDAQEPP---------APPPPLPPYASCSPRASLPAPPLPGVNS------- 318
++A P+ + P APP PL +S SL +P L +S
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL-ALSSLQATTSLGSPTLQATHSFLTMSPR 435
Query: 319 -------SSETPPPLPPKSPSFQAP---PQKAGAQALPAPPAPPGSQP 356
S P PP SP QAP P Q +P P S P
Sbjct: 436 QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP 483
Score = 66.2 bits (160), Expect = 6e-11
Identities = 99/379 (26%), Positives = 128/379 (33%), Gaps = 82/379 (21%)
Query: 76 SKGTNKEGGGSANTRGASTPPTLGDLFAGGF---PVLRPAGQRDV-AGGKTGQGP-GSRA 130
+K + G +A T A P L G P + PA R + A G G+ P RA
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 131 PSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPL 190
I G IP ++PR G T A ++R RP PA PP P
Sbjct: 63 GG-------IGGATIPESAPRAGPTRSAGTSSRNPASRP--PASGRGERAPPAKNTSPG- 112
Query: 191 PSSSPIKTPLVSPPGPLTKGNLPVVAP---------------------------PVPCAP 223
P SSP + + PGPL + L + A P P P
Sbjct: 113 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172
Query: 224 PPPP-------------PPPPPTPPPLPP--------ASVLSDKAVKPQLAPLHLPPIPP 262
P P P P+ P PP +S +P A P
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
Query: 263 PL-------------PLLPPC-GYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASL 308
L PL P P + P +PA +Q P L P PR
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD- 291
Query: 309 PAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPA--PPAPPGSQPF-LQKKRHGR 365
A P G SSS P P + + PP A LPA PP+PP + P L
Sbjct: 292 -AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
Query: 366 PGAGGGKLNPPPAPPARSP 384
P + +PP PP+++P
Sbjct: 351 PPSLQTLPSPPATPPSQAP 369
Score = 58.2 bits (139), Expect = 2e-08
Identities = 96/343 (27%), Positives = 117/343 (34%), Gaps = 82/343 (23%)
Query: 1 MPVPPPPP--PPL-----PPP--PPPLGAPP----PPPPSAPPVSTDTSSLRRADPKGRS 47
+ VPP PP PP+ PPP PPPL APP P PP++PP+S + R P +
Sbjct: 704 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763
Query: 48 ALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANT--RGASTPPTLGDLFAGG 105
L +V S P +K + A + +PP F G
Sbjct: 764 PPL----------QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS---FPGQ 810
Query: 106 FPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTA 165
P P+ ++ T P +AP P L + P PPASP L A
Sbjct: 811 AP-FSPSASLPMSPLAT---PPPQAP-PVLAAPLLQVPPSPPASPTL-----------QA 854
Query: 166 PPRPNVPAPPP------------PTPPPPPPPLP------PPLP--SSSPIKTP-----L 200
P RP P P P PPPPP P P L SSS TP
Sbjct: 855 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 914
Query: 201 VSPPGPLTKGNLPVVAPPVPC-------APPPP------PPPPPPTPPPLPPASVLSDKA 247
S P + P A C P PP P P P PP P S
Sbjct: 915 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 974
Query: 248 VKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPP 290
+ P P P L P G G KA + A + P
Sbjct: 975 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 1017
Score = 53.5 bits (127), Expect = 4e-07
Identities = 63/252 (25%), Positives = 97/252 (38%), Gaps = 19/252 (7%)
Query: 156 SEAHGAARTAPPR-PNVPAPPPPTPPPPPPPLPPP----LPSSSPI-KTPLVSPPGPLTK 209
++A AART R P + P PP P PPPP+ P L ++ + + PL G +
Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 210 GNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDK---AVKPQLAPLHLPPIPPPLPL 266
+P AP P P PPAS ++ A P+ P
Sbjct: 68 ATIPESAP--RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
Query: 267 LPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYA----SCSPRASLPAPPLPGVNSSSET 322
P G GL+ + AP + P P+P + + ++ T
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
Query: 323 PPPLPPKSPSFQ-APPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPA 381
LP +PS + PP + +++ + ++P +R RP AGGG L P +
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR--RPSAGGG-LQRPASRSL 242
Query: 382 RSPTTELSSKSQ 393
S T LSS ++
Sbjct: 243 SSSATPLSSPAR 254
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 138 bits (347), Expect = 1e-32
Identities = 134/432 (31%), Positives = 179/432 (41%), Gaps = 49/432 (11%)
Query: 11 LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSA 70
LP P P A P PP P S ++S +A G R ++ SA
Sbjct: 180 LPRPAP--SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 237
Query: 71 PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG--GKTGQGPGS 128
+ S + G+ + P L A P + P ++D A G P +
Sbjct: 238 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP-RKDAAPALGPLSSSPLA 296
Query: 129 RAPSPRLPNKTISGPLI-----PPASP------RLGN-TSEAHGAARTAPPRPNVPAPPP 176
PSP P + P + PPA+P LG+ T +A + +PP + PPP
Sbjct: 297 -TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355
Query: 177 PTPPPP--PPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP---- 230
PP PP PP P +SP +PL +P P L V P +PPP PP
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATP-SPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 231 PPTPPPLPPASVLSDKAVKPQLA--PLHLPPIPPPLPLLPPCGYPGLKAEP---ASPAQD 285
PP PP+ P++ +A P LA PL +PP PP P + P P +A P A P Q
Sbjct: 415 PPASPPVSPSATPPSQA-PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473
Query: 286 AQEPPAPPPPLPPYASCSPRASLPAPP--LPGVN--SSSETPPPLPPKSPSFQAPPQKAG 341
A+ PPP PP + P +LP+PP PG S S + P P +P QAPP A
Sbjct: 474 AK----PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA- 528
Query: 342 AQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNP---------PPAPPARSPTTELSSKS 392
A L PP+PP S +R PG P PP PP+RSP++ LS
Sbjct: 529 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 588
Query: 393 QQATAWTPTQQP 404
+ + T P
Sbjct: 589 LAGHSSSATSTP 600
Score = 112 bits (281), Expect = 6e-25
Identities = 125/416 (30%), Positives = 156/416 (37%), Gaps = 84/416 (20%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
+ P P PP P PP L P PP A P S T+SL + + L L
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPP--ATPPSQATTSLGSPTLQATHSFL----PSPPLS 348
Query: 61 KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR-DVAG 119
+ ++ P + + +PP L P+ P+ Q +
Sbjct: 349 PLATPPPQAPPAL-----------ALPPLQAPPSPPASPPL----SPLATPSPQAPNALA 393
Query: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVP--APPPP 177
Q P S PSP + P PPASP + ++ PP P A PP
Sbjct: 394 VHLLQAPFSPPPSP-----PVQAPFSPPASPPVSPSA--------TPPSQAPPSLAAPPL 440
Query: 178 TPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPL 237
PP PP PP PS++P P +PP P+ APP+ A PPP PP PPL
Sbjct: 441 QVPPSPPASPPMSPSATP---PPQAPP--------PLAAPPLQLAKPPPQAPPALATPPL 489
Query: 238 -----PPASVLSDKAVKPQLAPLHLPPIPPPLPLLPP-CGYPGLKAEPASPAQDA-QEPP 290
PPAS P A L + P+ P P PP P L+ P+ PA Q P
Sbjct: 490 QALPSPPASFPGQAPFSPS-ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548
Query: 291 APPPPLPPYASCSPRASL---PAPPLPGVNSSSET--PPPLPPKSPSFQAPPQ------- 338
PP P P + PR +L P PP P S S T P L S S + P+
Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608
Query: 339 --KAGAQALPAP--------PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
+ GA A P P PA P G PGA P P PPA P
Sbjct: 609 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA------PLPWPPATGP 658
Score = 110 bits (275), Expect = 3e-24
Identities = 138/487 (28%), Positives = 170/487 (34%), Gaps = 118/487 (24%)
Query: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVT 63
P P L P PP G+P PPPP P L A GR LA+ G +
Sbjct: 17 PAARAPGLLTPRPP-GSPRPPPPVTPAA---LRVLGAAGAVGRKP-LAERAGGIGGATIP 71
Query: 64 QINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR-------- 115
+ R+ P S + G + + S P A G P GQ+
Sbjct: 72 ESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 131
Query: 116 DVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGA-------ARTAPPR 168
VA GK + P A S T SGP SP + S A G A +A PR
Sbjct: 132 TVARGKATEAPKRSALSAGARRDT-SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190
Query: 169 PNVPAP--------------PPP------------------------TPPPPP------- 183
P P P P TP P
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250
Query: 184 --PPLPPPLPSS------SPIKTPLVSPP--------GPLTKGNLPVVAPPVPCAPPPPP 227
P P PS ++ P V+PP GPL+ L A P P APP P
Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL---ATPSPSAPPSPS 307
Query: 228 PPPP----PTPPPLPPASVLSDKAVKPQLAPLH-------LPPIPPPLPLLPPC-GYPGL 275
PP P+PP PP+ + P L H L P+ P P PP P L
Sbjct: 308 APPSLQTLPSPPATPPSQATTSLG-SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366
Query: 276 KAEPASPAQDAQEPPAPPPPLPPYASC-----SPRASLPAPPLPGVNSSSETPPPLPPKS 330
+A P+ PA P A P P P A +P + P+PP+ S +PP P +
Sbjct: 367 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 426
Query: 331 PSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPP--APPARSPTTEL 388
P QAPP A A L PP+PP S P P A PPP PP +P +L
Sbjct: 427 PPSQAPPSLA-APPLQVPPSPPASPPM-------SPSA-----TPPPQAPPPLAAPPLQL 473
Query: 389 SSKSQQA 395
+ QA
Sbjct: 474 AKPPPQA 480
Score = 72.4 bits (176), Expect = 9e-13
Identities = 105/429 (24%), Positives = 135/429 (31%), Gaps = 138/429 (32%)
Query: 114 QRDVA-GGKTGQGPGSRAP---SPRLPNKTISGPLIPPASPR------------------ 151
+RD A G + P +RAP +PR P P + PA+ R
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
Query: 152 -LGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKG 210
+G + A R P R + P PP P P SSP + + PGPL +
Sbjct: 64 GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123
Query: 211 NLPVVAP---------------------------PVPCAPPPPP-------------PPP 230
L + A P P P P P P
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183
Query: 231 PPTPPPLPP--------ASVLSDKAVKPQLAPLHLPPIPPPL-------------PLLPP 269
P+ P PP +S +P A P L PL P
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 270 C-GYPGLKAEPASPAQDAQEPP------APPPPLPPYASCSP-----------RASLPAP 311
P + P +PA +Q P PP PP +P S AP
Sbjct: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP 303
Query: 312 PLPGVNSSSETPP--------------------------PLPPKSPSFQAPPQKAGAQAL 345
P P S +T P P PP SP PPQ A AL
Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 363
Query: 346 P---APPAPPGSQPF--LQKKRHGRPGAGGGKL-----NPPPAPPARSPTTELSSKSQQA 395
P APP+PP S P L P A L +PPP+PP ++P + +S
Sbjct: 364 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 423
Query: 396 TAWTPTQQP 404
+A P+Q P
Sbjct: 424 SATPPSQAP 432
Score = 62.4 bits (150), Expect = 9e-10
Identities = 105/405 (25%), Positives = 130/405 (32%), Gaps = 122/405 (30%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSA-PPVSTDTSSLRRADPKGRSALLADIQQGTRL 59
+ PP PP PP PP+ PPP A PP++ L + P+ AL
Sbjct: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL---------- 484
Query: 60 RKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG 119
+ P +++ +PP FP
Sbjct: 485 ---------ATPPLQA----------------LPSPP-------ASFP------------ 500
Query: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
GQ P S PS LP ++ P PP +P + A P VP PP +P
Sbjct: 501 ---GQAPFS--PSASLPMSPLATP--PPQAPPV-----------LAAPLLQVPPSPPASP 542
Query: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239
P PP PGP T V P + A P PPPPP P
Sbjct: 543 TLQAPRRPP--------------TPGPDTS----VSGPRLTLALAPGPPPPPSR----SP 580
Query: 240 ASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPY 299
+S LS P LA P L G + P A A PPP
Sbjct: 581 SSTLSG----PDLAGHSSSATSTPEEL------RGYDSGPEGGA------AASPPPDAEL 624
Query: 300 ASCSPRA--SLPAPPLPGVNSSSETPPPLPPKSPSFQAP------PQKAGAQALPAPPA- 350
A+C P A PAPPL + P P PP + A + A PAP A
Sbjct: 625 AACHPAAWSRGPAPPL-AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 683
Query: 351 PPGSQPFLQ-KKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQ 394
PG P K GAG +P A P L + Q
Sbjct: 684 DPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQ 728
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 131 bits (329), Expect = 2e-30
Identities = 135/461 (29%), Positives = 177/461 (38%), Gaps = 77/461 (16%)
Query: 11 LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSA 70
LP P P A P PP P S ++S +A G R ++ SA
Sbjct: 189 LPRPAP--SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
Query: 71 PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG--GKTGQGPGS 128
+ S + G+ + P L A P + P ++D A G P +
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP-RKDAAPALGPLSSSPLA 305
Query: 129 RAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPA-----PPPPTPPP-- 181
PSP ++ + P +P T + APP P+ P P PP PP
Sbjct: 306 -TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 364
Query: 182 -----------------PPPPLPP---PLPSSSPIKT--PLVSPPGPLTKGNLPVVAPPV 219
P PPL P P P + P PL +PP P L +A P
Sbjct: 365 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 424
Query: 220 PCAP-------------PPPPPP-----PPPTPPPLPPASVLSDKAVKPQLA--PLHLPP 259
P AP PPP PP PP PP+ P++ +A P LA PL +PP
Sbjct: 425 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA-PPSLAAPPLQVPP 483
Query: 260 IPPPLPLLPPCGYPGLKAEP---ASPAQDAQEPPAPPPPLPPYASCSPRASLPAPP--LP 314
PP P + P P +A P A P Q A+ PPP PP + P +LP+PP P
Sbjct: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAK----PPPQAPPALATPPLQALPSPPASFP 539
Query: 315 GVN--SSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGK 372
G S S + P P +P QAPP A A L PP+PP S +R PG
Sbjct: 540 GQAPFSPSASLPMSPLATPPPQAPPVLA-APLLQVPPSPPASPTLQAPRRPPTPGPDTSV 598
Query: 373 LNP---------PPAPPARSPTTELSSKSQQATAWTPTQQP 404
P PP PP+RSP++ LS + + T P
Sbjct: 599 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 639
Score = 111 bits (277), Expect = 2e-24
Identities = 125/416 (30%), Positives = 156/416 (37%), Gaps = 84/416 (20%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
+ P P PP P PP L P PP A P S T+SL + + L L
Sbjct: 334 LATPLPLAPPSPSAPPSLQTLPSPP--ATPPSQATTSLGSPTLQATHSFL----PSPPLS 387
Query: 61 KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR-DVAG 119
+ ++ P + + +PP L P+ P+ Q +
Sbjct: 388 PLATPPPQAPPAL-----------ALPPLQAPPSPPASPPL----SPLATPSPQAPNALA 432
Query: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVP--APPPP 177
Q P S PSP + P PPASP + ++ PP P A PP
Sbjct: 433 VHLLQAPFSPPPSP-----PVQAPFSPPASPPVSPSA--------TPPSQAPPSLAAPPL 479
Query: 178 TPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPL 237
PP PP PP PS++P P +PP P+ APP+ A PPP PP PPL
Sbjct: 480 QVPPSPPASPPMSPSATP---PPQAPP--------PLAAPPLQLAKPPPQAPPALATPPL 528
Query: 238 -----PPASVLSDKAVKPQLAPLHLPPIPPPLPLLPP-CGYPGLKAEPASPAQDA-QEPP 290
PPAS P A L + P+ P P PP P L+ P+ PA Q P
Sbjct: 529 QALPSPPASFPGQAPFSPS-ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 587
Query: 291 APPPPLPPYASCSPRASL---PAPPLPGVNSSSET--PPPLPPKSPSFQAPPQ------- 338
PP P P + PR +L P PP P S S T P L S S + P+
Sbjct: 588 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 647
Query: 339 --KAGAQALPAP--------PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
+ GA A P P PA P G PGA P P PPA P
Sbjct: 648 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA------PLPWPPATGP 697
Score = 105 bits (263), Expect = 7e-23
Identities = 141/472 (29%), Positives = 172/472 (36%), Gaps = 88/472 (18%)
Query: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVT 63
P P L P PP G+P PPPP P L A GR LA+ G +
Sbjct: 17 PAARAPGLLTPRPP-GSPRPPPPVTPAA---LRVLGAAGAVGRKP-LAERAGGIGGATIP 71
Query: 64 QINDRSAPQIESSKGTNKEGGGS---ANTRGASTPP--------------TLGDLFAG-- 104
+ R+ P S GT+ S A+ RG PP G G
Sbjct: 72 ESAPRAGP--TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 105 GFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAART 164
G LR + + VA GK + P A S T SGP SP + S A G
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDT-SGPTPGTPSPAMARRSRAAG-TEV 187
Query: 165 APPRPNVPA-PPPPTPPP-------------PPPPLPPPLPSS------------SPIKT 198
PRP A P PPT P P P PS+ S T
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 199 PLVSP--PGPLTKGNLPVVAPPVPCAPPPPPP-------PPPPTPPPLPPASVLSDKAVK 249
PL SP GP +G P P P P P PP TPP A L +
Sbjct: 248 PLSSPARSGPSARG-----TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
Query: 250 PQLAPLHLPPI----PPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPP-----PLPPYA 300
P P + PP LP P L + A+P A P+ PP P PP
Sbjct: 303 PLATPSPSAALQSQAPPTLPATPHSS--SLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
Query: 301 SCS-PRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPF-- 357
S SL +P L +S +PP P +P QAPP A L APP+PP S P
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA-LPPLQAPPSPPASPPLSP 419
Query: 358 LQKKRHGRPGAGGGKL-----NPPPAPPARSPTTELSSKSQQATAWTPTQQP 404
L P A L +PPP+PP ++P + +S +A P+Q P
Sbjct: 420 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 471
Score = 72.8 bits (177), Expect = 7e-13
Identities = 115/440 (26%), Positives = 144/440 (32%), Gaps = 135/440 (30%)
Query: 76 SKGTNKEGGGSANTRGASTPPTLGDLFAGGF---PVLRPAGQRDV-AGGKTGQGP-GSRA 130
+K + G +A T A P L G P + PA R + A G G+ P RA
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 131 PSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPL 190
I G IP ++PR G T A ++R RP PA PP P
Sbjct: 63 GG-------IGGATIPESAPRAGPTRSAGTSSRNPASRP--PASGRGERAPPAKNTSPG- 112
Query: 191 PSSSPIKTPLVSPPGPLTKGNLPVVAP---------------------------PVPCAP 223
P SSP + + PGPL + L + A P P P
Sbjct: 113 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172
Query: 224 PP-----------------PPP---PPPPTPPPLPPASVLSD------------------ 245
P P P P PPT P S S+
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
Query: 246 -------KAVKPQLAPLHLP----------PIPPPLPLLP-PCGYPGLKAEPASPAQDAQ 287
+++ PL P P P P P P G L+ +P +
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
Query: 288 EPPAPPPPLPPYASCSPRASLPA---PPLPGVNSSSE------TPPPLPPKSPSFQAPPQ 338
P P P A+ SP A+L + P LP SS TP PL P SPS APP
Sbjct: 293 APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS--APP- 349
Query: 339 KAGAQALPAPPAPPGSQ-----------------------PFLQKKRHGRPGAGGGKLNP 375
Q LP+PPA P SQ P P L
Sbjct: 350 --SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407
Query: 376 PPAPPARSPTTELSSKSQQA 395
PP+PPA P + L++ S QA
Sbjct: 408 PPSPPASPPLSPLATPSPQA 427
Score = 62.4 bits (150), Expect = 9e-10
Identities = 105/405 (25%), Positives = 130/405 (32%), Gaps = 122/405 (30%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSA-PPVSTDTSSLRRADPKGRSALLADIQQGTRL 59
+ PP PP PP PP+ PPP A PP++ L + P+ AL
Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL---------- 523
Query: 60 RKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG 119
+ P +++ +PP FP
Sbjct: 524 ---------ATPPLQA----------------LPSPP-------ASFP------------ 539
Query: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
GQ P S PS LP ++ P PP +P + A P VP PP +P
Sbjct: 540 ---GQAPFS--PSASLPMSPLATP--PPQAPPV-----------LAAPLLQVPPSPPASP 581
Query: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239
P PP PGP T V P + A P PPPPP P
Sbjct: 582 TLQAPRRPP--------------TPGPDTS----VSGPRLTLALAPGPPPPPSR----SP 619
Query: 240 ASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPY 299
+S LS P LA P L G + P A A PPP
Sbjct: 620 SSTLSG----PDLAGHSSSATSTPEEL------RGYDSGPEGGA------AASPPPDAEL 663
Query: 300 ASCSPRA--SLPAPPLPGVNSSSETPPPLPPKSPSFQAP------PQKAGAQALPAPPA- 350
A+C P A PAPPL + P P PP + A + A PAP A
Sbjct: 664 AACHPAAWSRGPAPPL-AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 722
Query: 351 PPGSQPFLQ-KKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQ 394
PG P K GAG +P A P L + Q
Sbjct: 723 DPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQ 767
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 128 bits (321), Expect = 1e-29
Identities = 143/509 (28%), Positives = 175/509 (34%), Gaps = 98/509 (19%)
Query: 6 PPPPPLPPPPPPLGAPPPP---PPS--------------APPVSTDTSSLRRADPKGRSA 48
P P +P P P GAP PP PPS PP +T S PKG A
Sbjct: 925 PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS------PKGGPA 978
Query: 49 LLADIQQGTRLRKVTQINDRSAPQIESSKGT---------NKEGGGSAN--TRGASTPPT 97
+ T T + + P S KG + +G +A +GASTPP
Sbjct: 979 TPSPKGAPTP-PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 98 LGDLFAGGFPVLRPAGQ-----------RDVAGGKTGQGPGSRAPSPRLPNKTISGPLIP 146
G P P + G T G+ P P GP P
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097
Query: 147 -----PASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLV 201
P P S G A PP P P TPP P L P P +P TP
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLA--TPPHKGAPTTPAATPPSPKGGLATPPPKGAP-TTPAA 1154
Query: 202 SPPGPLTKGNL----PVVAPPVPCAPPPPP-----PPPPPTPPPLPPASVLSDKAVKPQL 252
+PP P KG L P AP P A PP P P P P P A+ S K
Sbjct: 1155 TPPSP--KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212
Query: 253 APLHLPPIPPPLPLLPPCGY--PGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPA 310
+P P P P P G P K P +PA P P PP + +P A+ P
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP- 1271
Query: 311 PPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAP---PAPPGSQPFLQKKRHGRPG 367
P + TPP +P+ PP G A P P PP + P K G P
Sbjct: 1272 ---PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328
Query: 368 AGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHS 427
G P PPA +P + + + AT TP+ + G T S
Sbjct: 1329 PKGA-----PTPPAVTPPSPKGTPTLPAT--TPSSKGGP-----------------TTPS 1364
Query: 428 VEDFPPPDEYKPCQKIYPSKIPRSRTPGP 456
++ P P P K P+ P S GP
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGP 1393
Score = 113 bits (283), Expect = 3e-25
Identities = 121/431 (28%), Positives = 149/431 (34%), Gaps = 68/431 (15%)
Query: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRAD-PKGRSALLADIQQGTRLRKV 62
P PP P P P + P + PP T T S+ PK A A Q +
Sbjct: 856 PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ--APALSM 913
Query: 63 TQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKT 122
T + + A + KG S + +GA TPP A
Sbjct: 914 TSSSPKKARATPAPKGI----PASPSPKGAPTPP---------------------AATPP 948
Query: 123 GQGPGSRAPSPR-LPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRP-NVPAPPPPTPP 180
G PSP+ P + P P P + A PP P PA P P
Sbjct: 949 SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGA 1008
Query: 181 PPPPPLPPPLPSSSPIKTPL---------VSPPGPLTKGN-----LPVVAPPVPCAPPPP 226
P PP + PP P SP TP +PP P KG+ LP AP P A P
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP--KGSPAATPLPKGAPTTPAATLPS 1066
Query: 227 PPPPPPTP----PPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEP--A 280
P P TP P PPA+ P P+PP PP GL P
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP--AATPPSPKGGLATPPHKG 1124
Query: 281 SPAQDAQEPPAP----PPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336
+P A PP+P P P A +P A+ P+P TPPP + P
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP-----KGGLATPPPKGAPTTPAATP 1179
Query: 337 PQKAGAQALPAP---PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQ 393
P G A P+P P P + P K P G P PP SP L++ S
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP--SPKGGLATPSP 1237
Query: 394 QATAWTPTQQP 404
+ TP P
Sbjct: 1238 KGAPTTPAATP 1248
Score = 111 bits (277), Expect = 2e-24
Identities = 126/431 (29%), Positives = 156/431 (36%), Gaps = 49/431 (11%)
Query: 7 PPPPLPPPPPPLGAPPPPPPSA---PPVSTDTS---SLRRADPKGRSALLADIQQGTRLR 60
P PP PP P G P P P PP +T S L KG A +
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139
Query: 61 KVTQINDRSAPQIESSKGTNKEGG------GSANTRGASTPPTLGDLFAGGFPVLRPAGQ 114
T + AP ++ + +GG A T A+TPP+ GG P G
Sbjct: 1140 LATP-PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP----KGGLATPSPKGA 1194
Query: 115 RDVAGGKTGQGPGSRA-PSPRLPNKTISGPLIPPASPRLG-NTSEAHGAARTAPPRPNVP 172
G A PSP+ T P P SP+ G T GA T P P
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTT---PAATPPSPKGGLATPSPKGAPTTPAATPPSP 1251
Query: 173 APPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKG--NLPVVAPPVPCAPPPPPPPP 230
P TPPP P PP S +K L +PP KG N VV PP P P PP
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPS-LKGGLATPPH---KGAPNPAVVTPPSPKGGPATSPPK 1307
Query: 231 -PPTPPPLPPASVLSDKAVKP----QLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQD 285
PTPP P S P P PP P P L P P K P +P+
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL-PATTPSSKGGPTTPS-- 1364
Query: 286 AQEPPAPPPPLPPYASCSPRASLPAP------PLPGVNSSSETPPPLPPKSPSFQAPPQK 339
++E P PP P + P + P+P P P + +S PL PK ++
Sbjct: 1365 SKEGPTPPAATPSHKG-GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTRE 1423
Query: 340 AGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNP----PPAPPARSPTT--ELSSKSQ 393
A PP P KK GG P P PA +P + E + Q
Sbjct: 1424 GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483
Query: 394 QATAWTPTQQP 404
AT+ +P + P
Sbjct: 1484 VATSSSPKKAP 1494
Score = 110 bits (276), Expect = 2e-24
Identities = 110/420 (26%), Positives = 156/420 (37%), Gaps = 54/420 (12%)
Query: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKV 62
V PP P P PP GAP PP + P + S PKG A V
Sbjct: 1292 VTPPSPKGGPATSPPKGAPTPPAATPP---SPKGSPGTPPPKGAPTPPA----------V 1338
Query: 63 TQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKT 122
T + + P + ++ ++K G + +++ TPP GG + P+ +R A
Sbjct: 1339 TPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398
Query: 123 GQGPGSRAPSPRLPNKTISGP-------------LIPPA-SPRLGNTSEAHGAARTAPPR 168
P S A P P K + P L PPA +P + A A + P
Sbjct: 1399 KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458
Query: 169 PNVPAPPPPTPPPPPPPLPPPLP-----SSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP 223
P+ P PP P PP P SSSP K P + P P+ LP V +P +P
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP--ATPAPMGAPTLPAV---IPSSP 1513
Query: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA 283
P P P+ P + L K LAP IPP + + P P + +PA
Sbjct: 1514 KEVPATPSSRRDPIAPTATLLSKKTPATLAPKE-ALIPPAMTVPSPKKTPAIPTPKEAPA 1572
Query: 284 QDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343
+ + + PP + P S P+P + + +P P +P PP
Sbjct: 1573 TPSSKEASSPPAVTP----STYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628
Query: 344 ALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQ 403
A PAP P S P L P PA S T ++ + QA+ P ++
Sbjct: 1629 ATPAPKGTPTSPPVTP-----------SSLKDSPTSPA-SVTCKMGATVPQASKGLPAKK 1676
Score = 109 bits (273), Expect = 5e-24
Identities = 135/502 (26%), Positives = 165/502 (32%), Gaps = 107/502 (21%)
Query: 2 PVPPPPPPPLPPPPPPLGAPP----PPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
PV P P P + AP P PS PP T + ++ D ++ LA +
Sbjct: 709 PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGT-KKVDGISHTSALAPVASSP 767
Query: 58 RLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGAST------PPT----------LGDL 101
K D A SSKGT S + G S PPT +G+L
Sbjct: 768 ---KECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNL 824
Query: 102 FAGGFPV---------LRPAGQRDVAGGKTGQGPGSR--APSPR-----------LPNKT 139
+ PV L G +D P S AP+P LP K
Sbjct: 825 SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE 884
Query: 140 ISGPLI--------------PPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPP 185
P + P +P L TS + AR P +PA P P P PP
Sbjct: 885 TPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA 944
Query: 186 LPPPLPSSSPIKT--------PLVSPPGPLTKGN----LPVVAPPVPCAPPP-------- 225
PP P P P +PP P KG P AP P A PP
Sbjct: 945 ATPPSPKGGPATPSPKWAPTPPAATPPSP--KGGPATPSPKGAPTPPAATPPSPKGGPAT 1002
Query: 226 --------PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLP-------PIPPPLPLLPPC 270
PP PP+P P A+ A P A P P+P P P
Sbjct: 1003 PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA 1062
Query: 271 GYPGLKAEPASPA-QDAQEPPAPPPPLPPYASCSPR-ASLPAPPL---PGVNSSSETPPP 325
P K PA+P+ + A PPA PP P +P P PP P TPP
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH 1122
Query: 326 LPPKSPSFQAPPQKAGAQALPAP---PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPAR 382
+ PP G A P P P P + P K P G P PP
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP-- 1180
Query: 383 SPTTELSSKSQQATAWTPTQQP 404
SP L++ S + TP P
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATP 1202
Score = 102 bits (254), Expect = 8e-22
Identities = 128/499 (25%), Positives = 162/499 (32%), Gaps = 98/499 (19%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAP--PVSTDTS---SLRRADPKGRSALLADIQQG 56
P P P PP P G PPP AP P +T S L PKG A
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Query: 57 TRLRKVTQINDRSAPQIESSKGTNKEGG-GSANTRGASTPPTLGDLFAGGFPVLRP---A 112
+ T + + AP ++ + +GG + + +GA T P G P P A
Sbjct: 1205 PKGGLATP-SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263
Query: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPN-V 171
A + +G + P PN + P P P A PP P
Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323
Query: 172 PAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP---GPLTKGNLPVVAPPV--------P 220
P PPP P PP + PP P +P P +P GP T + PP P
Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPT-LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP 1382
Query: 221 CAPPPPPPPPPPTPPP----------------LPPASVLSDKAVKPQLAPLHLPPIPP-- 262
PP P P P P P V + A P L P + P
Sbjct: 1383 AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442
Query: 263 ----PLPLLPPCG--YPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPR------ASLPA 310
P P G P K +P PA P PP P S SP+ A + A
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502
Query: 311 PPLPGVNSSSETPPPLPP----------------KSPSFQAP-----------PQKAGAQ 343
P LP V SS P P K+P+ AP P
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTP 1562
Query: 344 ALPAP---PAPPGSQ-----PFLQKKRHGRPGAGGGKLNPP----------PAPPARSPT 385
A+P P PA P S+ P + + + L PP P PPA +P
Sbjct: 1563 AIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP 1622
Query: 386 TELSSKSQQATAWTPTQQP 404
+ + A TPT P
Sbjct: 1623 SPEKGPATPAPKGTPTSPP 1641
Score = 82.8 bits (203), Expect = 6e-16
Identities = 124/485 (25%), Positives = 160/485 (32%), Gaps = 111/485 (22%)
Query: 2 PVPPPPPP-----PLPPPPPPLGAPPPPPPSAPPVSTDTSSLRR----ADPKGRSALLAD 52
P PP P P PP P P P P P S L A P R
Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP 1428
Query: 53 IQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA 112
+ VT ++ + AP + KG G + +++G T P + P PA
Sbjct: 1429 SKGDLTPPAVTPVSLKKAPATSAPKG----GPATPSSKGDPTLPAV----TPPSPKEPPA 1480
Query: 113 GQRDVAGGKTGQGPGSRAP--SPRLPNKTISGPLIPPASPR------------LGNTSEA 158
++ + P + AP +P LP S P PA+P L + A
Sbjct: 1481 PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA 1540
Query: 159 HGAARTA--PPRPNVPAPPP----PTPPPPP----------PP----------------- 185
A + A PP VP+P PTP P PP
Sbjct: 1541 TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL 1600
Query: 186 LPPPLPSSSPIKT---PLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPT--PPPLPPA 240
+PP + S SP + P V+PP P KG A P P P PP P + P PA
Sbjct: 1601 IPPAVTSPSPKEAPTPPAVTPPSP-EKG----PATPAPKGTPTSPPVTPSSLKDSPTSPA 1655
Query: 241 SVLSDKAVKPQLAPLHLPP----------IPPPLPLLPPCGYPGLKAEPASPAQDAQEPP 290
SV A LP + P P P + P + A PP
Sbjct: 1656 SVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP 1715
Query: 291 APPPPLPPYASCSPRASL-PAPPLPGVNSSSETPP----------PLPPKSPSFQAP--- 336
P P S P +++ PAP LP SS+T PL P P
Sbjct: 1716 ICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTA 1775
Query: 337 ---------PQKAGAQALPAPPA----PPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARS 383
P+ A A P+PP P P L K+ P + G L P P A +
Sbjct: 1776 AAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA 1835
Query: 384 PTTEL 388
EL
Sbjct: 1836 DEDEL 1840
Score = 75.9 bits (185), Expect = 8e-14
Identities = 118/466 (25%), Positives = 164/466 (35%), Gaps = 68/466 (14%)
Query: 1 MPVPPPPPPPLPP----------------PPPPLGAPPPPP--PSAPPVSTDTSSLRRAD 42
+P PP P PP P P+GAP P PS+P T S RR
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDP 1526
Query: 43 PKGRSALLADIQQGTRLRKVTQINDR---SAPQIESSKGTNKEGGGSANTRGASTPPTLG 99
+ LL+ T K I +P+ + T KE + +++ AS+PP +
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586
Query: 100 DLFAGGFP----VLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTIS---GPLIPPASPRL 152
G P +L P + + P PSP T + P PP +P
Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646
Query: 153 GNTSEAHGAARTAPPRPNVPAPPPPTPPPP-PPPLPPPLPSSSPIKTPLVSPP---GPLT 208
S A+ T VP P P L L + +P TP+++ P GP T
Sbjct: 1647 LKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT 1706
Query: 209 KGNLPVVAPPVPCAPPPPP-----PPPPPTPPPLPPASVLSDKAVKPQLAPLHLP--PIP 261
K + +PP+ C P P P PL P S K K + A H P P+
Sbjct: 1707 KKS-SATSPPI-CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDAS-HSPKGPLA 1763
Query: 262 PP-----LPL--------LPPCGYPGLKAEPASPAQDAQEPPAPPPPLPP---YASCSPR 305
PP PL LP + A P SP P+P P LPP + SP
Sbjct: 1764 PPESKASTPLTAAAFEKVLPKPESASVSAAP-SPPVSLPLAPSPVPTLPPKQQFLPSSPG 1822
Query: 306 ASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAP-------PAPPGSQPFL 358
L +P P + + PL P P P ++ +P P P P QP
Sbjct: 1823 LVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPV- 1881
Query: 359 QKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQP 404
K + G P + T + ++Q A A ++P
Sbjct: 1882 -TKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEP 1926
Score = 50.1 bits (118), Expect = 5e-06
Identities = 73/274 (26%), Positives = 91/274 (33%), Gaps = 65/274 (23%)
Query: 185 PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPP------PLP 238
PL P + P+ + PL V+AP +P + P P PP TPP +
Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLAT---LVLAPEIPKSVPSPSLPPAGTPPGTKKVDGIS 755
Query: 239 PASVLSDKAVKPQLAP----------------LHLPPIPPPL--PLLPPCGYPGLKAEPA 280
S L+ A P+ P +L P PL + P P K A
Sbjct: 756 HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA 815
Query: 281 SPAQDAQEPPAPPPPLPPYASCSPRASL--------------PAPPLP-GVNSSSETPP- 324
P D P P AS P SL P PP P G + S P
Sbjct: 816 GP--DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPL 873
Query: 325 -----PLPPK---SPSFQAPPQKAGAQALPAPPAPP-----GSQPFLQKKRHGRPGAGGG 371
LPPK +PS P A PAP P S P KK P G
Sbjct: 874 SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP---KKARATPAPKGI 930
Query: 372 KLNP----PPAPPARSPTTELSSKSQQATAWTPT 401
+P P PPA +P + + + W PT
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT 964
Score = 47.4 bits (111), Expect = 3e-05
Identities = 65/243 (26%), Positives = 89/243 (36%), Gaps = 63/243 (25%)
Query: 168 RPNVPAPPPPTPPPPPPPLPP-----PLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCA 222
+P PPP +P P PL P PS S I + + P P + A P+ A
Sbjct: 40 QPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSG---TALPLGTA 96
Query: 223 PPPPPPPPPPTPPPLPPASV-LSDKAVKPQL-------APLHLPPI-----------PPP 263
P P P PP+ PA++ L+ + P L APL L + PP
Sbjct: 97 PEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPN 156
Query: 264 LPLLPP------------CGYPGLKAEPAS-----PAQDAQEPPAPPPP-----LPPYAS 301
L PP P +EP + P++ P P P PY
Sbjct: 157 LLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHC 216
Query: 302 CSPRASLPAPPLPGVNSSSETPP--PLPPKSP--------SFQAPPQKAGAQALPAPPAP 351
+P AS+ + GV S +T P L SP S PQ G+ +L P +P
Sbjct: 217 VTPMASIQS----GVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSP 272
Query: 352 PGS 354
P +
Sbjct: 273 PAA 275
Score = 45.8 bits (107), Expect = 9e-05
Identities = 58/201 (28%), Positives = 69/201 (34%), Gaps = 22/201 (10%)
Query: 171 VPAPPPPTPPPPPPPLPPP------LPSSSPIK-TPLVSPPGPLTKGNLPVVAPPVPCAP 223
+P T P LP P LP SS + T + PGP P PC+P
Sbjct: 1 MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTL---------PPPCSP 51
Query: 224 PPP--PPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLP--PCGYPGLKAEP 279
P P P P S ++ ++ P PL P P P L P
Sbjct: 52 APQQCPLSAANQASPFPSPSTIASTPLEVPF-PQSSSGTALPLGTAPEAPTFLPNLIGPP 110
Query: 280 ASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQK 339
SPA A P P L S S +L A V SS PP L PS A +
Sbjct: 111 ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSV-AVAES 169
Query: 340 AGAQALPAPPAPPGSQPFLQK 360
L AP AP + L K
Sbjct: 170 GSVITLSAPIAPSEPKTNLNK 190
Score = 41.2 bits (95), Expect = 0.002
Identities = 83/363 (22%), Positives = 118/363 (32%), Gaps = 58/363 (15%)
Query: 87 ANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISG---- 142
A+ GA P L P + P Q + Q S P P T++
Sbjct: 537 ASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLG 596
Query: 143 ---PLIPPASPR---LGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPI 196
P+ PAS LG S A + P+ P + P PL S+ P
Sbjct: 597 EPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPA 656
Query: 197 KTPLVSPPG-----------------------PLTKGNLPVVAPPVPCAPPPPPPPPPPT 233
+ G P+ +G L + P VP A P P P
Sbjct: 657 GVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTL-PLVPTASENCPVAPSPQ 715
Query: 234 PPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGY-PGLKAEPASPAQDAQEPPAP 292
P A+++ + P++ P P P LPP G PG K A P A
Sbjct: 716 NTCAPLATLV----LAPEI------PKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS 765
Query: 293 PPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPK-SPSFQAPPQKAGAQALPAP--- 348
P P AS A + +++P PL SP + PP K G+ P
Sbjct: 766 SPKECPTEDSG--ASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGN 823
Query: 349 ---PAPPGSQPFLQKKR---HGRPGAGGGKLNPPPAPPARSPT-TELSSKSQQATAWTPT 401
P P FL + G + +P P P +PT + ++ S + P
Sbjct: 824 LSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPK 883
Query: 402 QQP 404
+ P
Sbjct: 884 ETP 886
Score = 38.1 bits (87), Expect = 0.018
Identities = 51/205 (24%), Positives = 69/205 (33%), Gaps = 19/205 (9%)
Query: 140 ISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTP 199
++ P+I P ++S AP + PP PP + S +
Sbjct: 118 LASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSA 177
Query: 200 LVSPPGPLTKGN-LPVVAPPVPCAPPPPPPPPPPTPPPL--PPASVLSDKAVKPQLAPLH 256
++P P T N +P P P P PP P P AS+ S A PQ P
Sbjct: 178 PIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTT 237
Query: 257 LPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGV 316
I P + + P +P + + P PP SL LP V
Sbjct: 238 TLAIASPQ--VKDTTISSVLISPQNPGSLSLKGPVSPPAA---------LSLSTQSLPVV 286
Query: 317 NSSSET-----PPPLPPKSPSFQAP 336
SS +T PP P S AP
Sbjct: 287 TSSQKTAGPNTPPDFPISLGSHLAP 311
Score = 33.9 bits (76), Expect = 0.34
Identities = 63/282 (22%), Positives = 94/282 (33%), Gaps = 38/282 (13%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
P PPP P P PL A P P + ++ L P+ S + GT
Sbjct: 43 PTLPPPCSP-APQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPL--GTAPEA 99
Query: 62 VTQINDRSAPQIESSK---GTNKEGGGSANTRGASTPPTLGDLF------AGGFPVLRPA 112
T + + P I + + T +S P L L + FP
Sbjct: 100 PTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLT 159
Query: 113 GQRDVAGGKTGQGPGSRAPSP---------RLPNKTISGPLIPPASPRLGNTSEAHGAAR 163
VA ++G AP ++P++ + P P+ P + +T H
Sbjct: 160 SPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTP 219
Query: 164 TAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPP----- 218
A + V A P T P + P + I + L+SP P + V+PP
Sbjct: 220 MASIQSGV-ASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSL 278
Query: 219 ----VPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLH 256
+P P TPP P ++ LAPLH
Sbjct: 279 STQSLPVVTSSQKTAGPNTPPDFP-------ISLGSHLAPLH 313
Score = 33.9 bits (76), Expect = 0.34
Identities = 84/353 (23%), Positives = 124/353 (35%), Gaps = 60/353 (16%)
Query: 22 PPPPPSAPPVSTD-----TSSLRRADPK-------GRSALLADIQQGT----RLRKVTQI 65
P PP+A +ST TSS + A P + LA + Q + +L T
Sbjct: 269 PVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGP 328
Query: 66 NDRSAPQIESSKGTNKEGGGSANTRGASTPPT-----LGDLFAGGFPVLRPAGQR----- 115
+ S P +++ + G S ++ + PP + FPV+ P+ +
Sbjct: 329 SALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTI 388
Query: 116 -----DVAGGKTGQGPGSRAPSPRL-----PNKTISGPLIP--PASPRLGNTSEAHGAAR 163
+G S +P+ L PN T PL+ P S + G
Sbjct: 389 SSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVS--------SVGTTP 440
Query: 164 TAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP 223
P A P T + PP+ SS PI + P L + P A
Sbjct: 441 LVVTNPCTIAAAPTTTFEVATCVSPPM-SSGPISNIEPTSPAALVMAPVAPKEPSTQVAT 499
Query: 224 PPPPPPPPPTPPPLP----PASVL----SDKAVKPQLAPLHLPPIPPPLPLL----PPCG 271
P PP P P P+SVL + K ++ A L P P L P
Sbjct: 500 TLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTV 559
Query: 272 YPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPP 324
P ++A P + +P PL P A+ + + SL P G +SS T P
Sbjct: 560 LPLVQAAPKNSPSFQSTSSSPEIPLSPEATLA-KKSLGEPLPIGKPASSMTSP 611
Score = 33.5 bits (75), Expect = 0.44
Identities = 31/117 (26%), Positives = 42/117 (35%), Gaps = 11/117 (9%)
Query: 263 PLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSET 322
P P P A + A P PPP P C A+ A P P ++ + T
Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAST 76
Query: 323 PPPLP-PKSPSFQAPPQKAGAQA------LPAPPAPPG----SQPFLQKKRHGRPGA 368
P +P P+S S A P +A L PP P + P + G P +
Sbjct: 77 PLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSS 133
Score = 31.6 bits (70), Expect = 1.7
Identities = 81/331 (24%), Positives = 108/331 (32%), Gaps = 81/331 (24%)
Query: 141 SGPL--IPPASPRLGNTSEAHGAARTAPPRPNVPAPP----PPTPPPPPPPLPPPLPSSS 194
SGP+ I P SP A A AP P+ P +PP P P LPSS
Sbjct: 469 SGPISNIEPTSPA------ALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSV 522
Query: 195 PIKTPLV------------SPPGP----LTKGNLPVVAPPVPCAPPPPPPPPPPTPP--- 235
+K P +P P LT P V P V AP P +
Sbjct: 523 LVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEI 582
Query: 236 PLPPASVLSDKAVKPQLAPLHLPPIPPPLPL---------------LPPCGYPGLKAEPA 280
PL P + L+ K++ L P+ P PL P P LK+
Sbjct: 583 PLSPEATLAKKSLGEPL-PIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLI 641
Query: 281 SPAQDA--QEPPAPPPPLPPYASCSPRASLPAPP----------------------LPGV 316
+P A E P P A + + A P LP V
Sbjct: 642 TPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLV 701
Query: 317 NSSSETPPPLPPKSPSFQAPPQKAGA------QALPAPPAPPGSQPFLQKKRHGRPGAGG 370
++SE P P SP P +++P+P PP P KK G
Sbjct: 702 PTASENCPVAP--SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSA 759
Query: 371 GKLNPPPAPPARSPTTELSSKSQQATAWTPT 401
L P + P PT + + + ++ T T
Sbjct: 760 --LAPVASSPKECPTEDSGASATASSKGTLT 788
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 118 bits (296), Expect = 1e-26
Identities = 118/406 (29%), Positives = 138/406 (33%), Gaps = 97/406 (23%)
Query: 2 PVPPPPPPPLPPPPPPLGA------PPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQ 55
P PPPPP P PPP G PPP P PP D S R+ P
Sbjct: 68 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP------------ 115
Query: 56 GTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR 115
PQ +G N+ G PP G +P G
Sbjct: 116 -------------GKPQGPPPQGGNQPQG---------PPPPPG----------KPQGPP 143
Query: 116 DVAGGKTGQGPGS----RAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV 171
G K QGP + P P+ NK+ S PP P+ G + + PP P
Sbjct: 144 PQGGNKP-QGPPPPGKPQGPPPQGDNKSRSSRS-PPGKPQ-GPPPQGGNQPQGPPPPPGK 200
Query: 172 PAPPPPT-------PPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP 224
P PPP PPPP P PP P SPPG P PP P
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPP-PQGDNKSQSARSPPGK------PQGPPPQGGNQP 253
Query: 225 PPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQ 284
PPPPP P PP KPQ P PP P PP + S ++
Sbjct: 254 QGPPPPPGKPQGPPPQG-----GNKPQGPP------PPGKPQGPP-------PQGGSKSR 295
Query: 285 DAQEPPAPPPPLPPYASCSPRASLP------APPLPGVNSSSETPPPLPPKSPSFQAPPQ 338
++ PP P PP P+ P PP G N PPP P+ P Q +
Sbjct: 296 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK 355
Query: 339 KAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
A++ P P P Q G P GG P APPA P
Sbjct: 356 SRSARSPPGKPQGPPQQE--GNNPQGPPPPAGGNPQQPQAPPAGQP 399
Score = 114 bits (286), Expect = 2e-25
Identities = 112/361 (31%), Positives = 130/361 (36%), Gaps = 53/361 (14%)
Query: 71 PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVL--RPAGQRDVAGGKT-GQGPG 127
PQ +G NK G + PP G G P +P G G K G P
Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 95
Query: 128 SRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT-------PP 180
+ P P PP P+ G + + PP P P PPP PP
Sbjct: 96 GKPQGPPPQGDKSRSPRSPPGKPQ-GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 154
Query: 181 PPPPPLPPPLPSSSPIKTPLVSPPG-----PLTKGNLPVVAPPVPCAPPPPPP------- 228
PP P PP P SPPG P GN P PP P P PPP
Sbjct: 155 PPGKPQGPP-PQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 213
Query: 229 -PPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA-QDA 286
PPPP P PP D + +P P PPP P G P +P P Q
Sbjct: 214 GPPPPGKPQGPPPQ--GDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 271
Query: 287 QEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALP 346
+P PPPP P PP G S S PP P Q PP + G Q P
Sbjct: 272 NKPQGPPPPGKPQGP---------PPQGGSKSRSSRSPPGKP-----QGPPPQGGNQ--P 315
Query: 347 APPAPPGSQPFLQKKRHGRPGAGGGK-LNPPPAPPARSPTTELSSKSQQATAWTPTQQPG 405
P PP +P G P GG K PPP + P + SKS+ A +P +P
Sbjct: 316 QGPPPPPGKP------QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR--SPPGKPQ 367
Query: 406 G 406
G
Sbjct: 368 G 368
Score = 110 bits (274), Expect = 4e-24
Identities = 100/319 (31%), Positives = 118/319 (36%), Gaps = 64/319 (20%)
Query: 117 VAGGKTGQGP-GSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPP 175
+AG G P G P GP PP P+ G + + PP P P P
Sbjct: 32 IAGNPQGAPPQGGNKPQ---------GPPSPPGKPQ-GPPPQGGNQPQGPPPPPGKPQGP 81
Query: 176 PPT-------PPPPPPPLPPPLPSSSPIKTPLVSPPG-----PLTKGNLPVVAPPVPCAP 223
PP PPPP P PP P ++P SPPG P GN P PP P P
Sbjct: 82 PPQGGNKPQGPPPPGKPQGPP-PQGDKSRSPR-SPPGKPQGPPPQGGNQPQGPPPPPGKP 139
Query: 224 PPPPP--------PPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGL 275
PPP PPPP P PP D + +P P PPP P G P
Sbjct: 140 QGPPPQGGNKPQGPPPPGKPQGPPPQ--GDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP 197
Query: 276 KAEPASPA-QDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQ 334
+P P Q +P PPPP P P P + S+ +PP P Q
Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKPQG--------PPPQGDNKSQSARSPPGKP------Q 243
Query: 335 APPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPP------APPARSPTTEL 388
PP + G Q P P PP +P G P GG K PP PP + +
Sbjct: 244 GPPPQGGNQ--PQGPPPPPGKP------QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR 295
Query: 389 SSKSQQATAWTPTQQPGGQ 407
SS+S P Q G Q
Sbjct: 296 SSRSPPGKPQGPPPQGGNQ 314
Score = 85.5 bits (210), Expect = 1e-16
Identities = 91/320 (28%), Positives = 103/320 (32%), Gaps = 56/320 (17%)
Query: 2 PVPPPPPPPLPPPPPPLGA------PPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQ 55
P PPPPP P PPP G PPP P PP D S P G+
Sbjct: 129 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGK--------- 179
Query: 56 GTRLRKVTQINDRSAPQIESSKGTNK-EGGGSANTRGASTPPTLGDLFAGGFPVLRPAG- 113
PQ +G N+ +G + PP G+ G P +P G
Sbjct: 180 ---------------PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 224
Query: 114 --QRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV 171
Q D PG P GP PP P+ G + + PP
Sbjct: 225 PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-GPPPQGGNKPQGPPPPGKP 283
Query: 172 PAPPP--------PTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP 223
PPP PP P PPP + P P PPG P PP
Sbjct: 284 QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP--PPPGK------PQGPPPQGGNK 335
Query: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEP-ASP 282
P PPPP P P S A P P P P PP G +P A P
Sbjct: 336 PQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395
Query: 283 AQDAQEPPAPP----PPLPP 298
A Q PP PP P PP
Sbjct: 396 AGQPQGPPRPPQGGRPSRPP 415
Score = 43.5 bits (101), Expect = 4e-04
Identities = 37/106 (34%), Positives = 42/106 (39%), Gaps = 17/106 (16%)
Query: 310 APPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAG 369
APP G + PP PP P Q PP + G Q PP PPG K G P G
Sbjct: 39 APPQGG---NKPQGPPSPPGKP--QGPPPQGGNQP-QGPPPPPG-------KPQGPPPQG 85
Query: 370 GGKLN--PPPAPPARSPTTELSSKSQQATAWTPTQQP--GGQLRNG 411
G K PPP P P S+S ++ P P GG G
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 131
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 114 bits (286), Expect = 2e-25
Identities = 123/456 (26%), Positives = 169/456 (37%), Gaps = 64/456 (14%)
Query: 2 PVPPPPPPPLPPP----PPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
P P PPPPLPPP PPPL PPPPP S PP+ + P A +
Sbjct: 408 PPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPS---------PPPPPAQEEQEESPP 458
Query: 58 RLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGG----FPVLRPAG 113
+ T R P + S+ +E A G S P GG P + P
Sbjct: 459 PVVPATCSRKRGRPPLTPSQRAERE-AARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKS 517
Query: 114 QRDVAGGKTGQGPGSRAPSPRL---PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPN 170
+ + P A S R+ P + + PP P++ + T+PP P
Sbjct: 518 TTFLKNIRQFIMPVVSARSSRVIKTPRRFMDED--PPKPPKVEVSPVLRPPITTSPPVPQ 575
Query: 171 VPAP---PPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPP 227
PAP PP P PP P+P P S ++ P + +P PP PP
Sbjct: 576 EPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTF---------RWTSLTRELPPPPPAPP 626
Query: 228 PPPPPTPPPLPPASVLSDKAVK-PQLAP--LHLPPIPPPLPLLPPCGYPGLKAEPASPAQ 284
PPP P+PPP P S ++ PQ P HL I + PP G P PA
Sbjct: 627 PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHL-KIYESVLTPPPLGAPEAPEPEPPPAD 685
Query: 285 DAQEPPAPP----------PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQ 334
D+ P P P P + +A + P +++ +T L Q
Sbjct: 686 DSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQL---LQPLQ 742
Query: 335 APPQKAGAQALP------APPAPPGSQPFLQKKR----HGRPGAGGGKLNPPPAPPARSP 384
A + QALP PP P P L+K R P +G + A+
Sbjct: 743 ALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQ 802
Query: 385 TTELSSKSQQATAWTPTQQPGGQLRN--GSLHIIDD 418
++ + QQ A + PGGQ+ G++ I D
Sbjct: 803 LFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISD 838
Score = 85.5 bits (210), Expect = 1e-16
Identities = 105/371 (28%), Positives = 126/371 (33%), Gaps = 87/371 (23%)
Query: 70 APQIES----SKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR-----DVAGG 120
AP+IE GT+ E RG TPP+ + G VL AG R D+
Sbjct: 2055 APRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAG--VLGAAGDRARPPEDLPSE 2112
Query: 121 ------KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAART---APPRPNV 171
K GPG PR + + PL + P G T+ RT P P V
Sbjct: 2113 IVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGV 2172
Query: 172 ------PAPPPPTPP------------------------PPP---PPLPPPLPSSSPIKT 198
PAP PP P PPP PPLPP + ++P
Sbjct: 2173 RVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSW 2232
Query: 199 PLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP--PPTPPPLPPASVLSDKAVKPQLAPLH 256
L PPGPL G LPVV P PPPPPP + P PP + K V
Sbjct: 2233 TL--PPGPLL-GVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSG--R 2287
Query: 257 LPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAP----- 311
PP PPP KA +A E P L R P
Sbjct: 2288 SPPAPPP-----------YKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLD 2336
Query: 312 -PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQP--FLQKKRHGRPGA 368
PG + E+P PL +SP P PP P P L+ + H G
Sbjct: 2337 LDRPGEPAGEESPGPLQERSPLLPLPED--------GPPQVPDGPPDLLLESQWHHYSGE 2388
Query: 369 GGGKLNPPPAP 379
PP+P
Sbjct: 2389 ASSSEEEPPSP 2399
Score = 84.0 bits (206), Expect = 3e-16
Identities = 84/295 (28%), Positives = 107/295 (36%), Gaps = 88/295 (29%)
Query: 165 APPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP 224
A + PPPP PP P P PPPLP P SPP PL PP P +PP
Sbjct: 393 AAEKEEAKLPPPPLTPPAPSP-PPPLP------PPSTSPPPPLCP------PPPPPVSPP 439
Query: 225 PPPPPPPP--------TPPPLPPASVLSDKAVKPQLAPLH--------------LPPIPP 262
P P PPPP +PPP+ PA+ S K +P L P PP P
Sbjct: 440 PLPSPPPPPAQEEQEESPPPVVPAT-CSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPT 498
Query: 263 P----------LPLLPPCGYPGLK-----AEPASPAQDA-----------QEPPAPP--- 293
P P + P LK P A+ + ++PP PP
Sbjct: 499 PSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVE 558
Query: 294 --PPLPPYASCS---PRASLPAPPLPGVNSSSETPPPLPPKSPS-FQAPPQKAGAQALPA 347
P L P + S P+ P P P + TP PLP K S + P + +
Sbjct: 559 VSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTREL 618
Query: 348 PPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQ 402
PP PP P P P+PP T+ +A +TP++
Sbjct: 619 PPPPPAPPP-----------------PPAPSPPPAPATSSRRPLLLRAPQFTPSE 656
Score = 83.6 bits (205), Expect = 4e-16
Identities = 117/454 (25%), Positives = 151/454 (33%), Gaps = 98/454 (21%)
Query: 5 PPPPPPLPPPPPPLGA-----PPPPPPSAPPVSTDTSSLRRADP-KGRSALLADIQQGTR 58
P PPPP+ P G+ P P P P +S R +GR L + +
Sbjct: 250 PEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVS 309
Query: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR-DV 117
K ++ S +ES +G G P GG P + Q+ D
Sbjct: 310 RAKKVKMGQLSLG-LESGQGQ-----GQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDD 363
Query: 118 AGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPP-RPNVPAPPP 176
+ + + ++ ++P A E A PP P P+PPP
Sbjct: 364 EEEEKKEEEEKDKEGEEKEERAVAEEMMPAA--------EKEEAKLPPPPLTPPAPSPPP 415
Query: 177 PTPPP---PPPPL-PPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPV------------P 220
P PPP PPPPL PPP P SP PL SPP P + PPV P
Sbjct: 416 PLPPPSTSPPPPLCPPPPPPVSP--PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPP 473
Query: 221 CAP------------PPPPPPPPPTP------PP---------------------LPPAS 241
P P PP PTP PP +P S
Sbjct: 474 LTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVS 533
Query: 242 VLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYAS 301
S + +K + P PP + P P + P P + A P P P PP
Sbjct: 534 ARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTP 593
Query: 302 C----SPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPF 357
R+ L P + + E PPP P P PP A + P PA +P
Sbjct: 594 VPLPEKRRSILREPTFRWTSLTRELPPPPPAPPP----PP----APSPPPAPATSSRRPL 645
Query: 358 LQKKRHGRPGAGGGK-----LNPPP--APPARSP 384
L + P K L PPP AP A P
Sbjct: 646 LLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEP 679
Score = 60.8 bits (146), Expect = 3e-09
Identities = 42/128 (32%), Positives = 54/128 (42%), Gaps = 15/128 (11%)
Query: 277 AEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336
AE PA + +E PPPPL +P A P PPLP S+S PP PP P P
Sbjct: 387 AEEMMPAAEKEEAKLPPPPL------TPPAPSPPPPLP-PPSTSPPPPLCPPPPPPVSPP 439
Query: 337 PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQAT 396
P LP+PP PP + + P K PP P++ E + + T
Sbjct: 440 P-------LPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGT 492
Query: 397 AWTPTQQP 404
+ PT P
Sbjct: 493 S-PPTPTP 499
Score = 59.3 bits (142), Expect = 8e-09
Identities = 109/446 (24%), Positives = 140/446 (31%), Gaps = 77/446 (17%)
Query: 6 PPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQI 65
P PP P PL PPP A P + LR P L
Sbjct: 1907 PAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTS----------- 1955
Query: 66 NDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDL-FAGGFPVLRPAGQRDVAGGKTGQ 124
+ + P S ++ G + + DL FA P + VA G G
Sbjct: 1956 GELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGS 2015
Query: 125 ---GPGSRA-----PSPR---LPNKTISGP-LIPPASP------RLGNTSEAHGAARTAP 166
GPG + P+ R P +S P L P A+P +L + + A
Sbjct: 2016 SHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAV 2075
Query: 167 PRPNVPAPPPPTP--------------PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNL 212
+P PP P PP LP S + L + GP G
Sbjct: 2076 QQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLP-----SEIVDFVLKNLGGPGDGG-- 2128
Query: 213 PVVAPPVPCAPPPPP------PPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIP-PPLP 265
P PP PP P T P P + P + L L P P PP P
Sbjct: 2129 --AGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKP 2186
Query: 266 LLPPCGYPGLKAEPASPAQDAQEPPAPP---PPLPPYASCSPRAS--LPAPPLPGVNSSS 320
+ EP PP PPLPP S + S LP PL GV
Sbjct: 2187 ATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVV 2246
Query: 321 ETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPP 380
P PP PP L + PA P Q K+ G +PP PP
Sbjct: 2247 GVVRPAPP-------PPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGR-----SPPAPPP 2294
Query: 381 ARSPTTELSSKSQQATAWTPTQQPGG 406
++P + ++ + T P GG
Sbjct: 2295 YKAPRLDEDGEASEDTPQVPGLGSGG 2320
Score = 56.2 bits (134), Expect = 6e-08
Identities = 92/368 (25%), Positives = 129/368 (35%), Gaps = 64/368 (17%)
Query: 86 SANTRGASTPPTLGDLFAGGFPV-----------LRP-AGQRDVAGGKTGQGPGSRAPS- 132
S+ G PP D+ G P LRP +G ++ G + P+
Sbjct: 1811 SSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNY 1870
Query: 133 --PRLPNKTIS-GPLIPPASPRLGNTSEAHGAART------APPRPNV-PAPPPPTPPPP 182
R P +S GPL P SP +S H APPR + P+P P PPP
Sbjct: 1871 SPSRRPLGGVSFGPLPSPGSP----SSLTHHIPTVGDPDFPAPPRRSRRPSPLAPR-PPP 1925
Query: 183 PPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASV 242
PPL +S ++ P PP + P P P P PPPP P V
Sbjct: 1926 SRWASPPLKTSPQLRVP---PPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEV 1982
Query: 243 LSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP-------PPP 295
+S + L P + G G + P ++E +P P
Sbjct: 1983 VSGLSAADLDFAASLLGTEPFQEEIVAAGAMG--SSHGGPGDSSEEESSPTSRYIHFPVT 2040
Query: 296 LPPYASCSPRASLPAP---PLPGVNSSSETPPPLPPKSPSFQAPPQ-----------KAG 341
+ +P A+ AP L GV+ +++ + PP AG
Sbjct: 2041 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG 2100
Query: 342 AQALPAPPAPPGSQPFLQKKRHGRPGAGGG---KLNPPPAPP---ARSPTTELSSKSQQA 395
+A P P F+ K G PG GG + + PPAPP P+ L++
Sbjct: 2101 DRARPPEDLPSEIVDFVLKNL-GGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADP 2159
Query: 396 T---AWTP 400
T AW P
Sbjct: 2160 TRTFAWLP 2167
Score = 52.8 bits (125), Expect = 7e-07
Identities = 66/274 (24%), Positives = 93/274 (33%), Gaps = 52/274 (18%)
Query: 182 PPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPAS 241
P P PP P+ T ++ P P P+ PP P PPP P S
Sbjct: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHS-------PIQNLDPPLRPDSGSAPPP-APRS 1859
Query: 242 VLSDKAVKPQLAPLHLP-------PIPPP------LPLLPPCGYPGLKAEPASPAQDAQE 288
+ P +P P P+P P +P G P A P + +
Sbjct: 1860 FSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPL 1919
Query: 289 PPAPPPP--LPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQK------- 339
P PPP P SP+ +P PP V + + T L P P+ PP +
Sbjct: 1920 APRPPPSRWASPPLKTSPQLRVP-PPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFE 1978
Query: 340 -------AGAQALPAPPAPPGSQPFLQK--------KRHGRPGAGGGKLNPPPAPPARSP 384
A L + G++PF ++ HG PG + + P + P
Sbjct: 1979 DMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFP 2038
Query: 385 TTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDD 418
T +S A P+ PG R L +DD
Sbjct: 2039 VTVVS-----APGLAPSATPGAP-RIEQLDGVDD 2066
Score = 48.9 bits (115), Expect = 1e-05
Identities = 60/218 (27%), Positives = 77/218 (35%), Gaps = 42/218 (19%)
Query: 2 PVPPP----PPPP-----------LPPPP-----PPLGAPPPPPPSAPPVSTDTSSLRRA 41
PVPPP P PP LPP P P +G P PP PP T S A
Sbjct: 2210 PVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPA 2269
Query: 42 DPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDL 101
P +Q R+++V+ + RS P K + G A + P + L
Sbjct: 2270 SPP---------RQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEA----SEDTPQVPGL 2316
Query: 102 FAGGF-------PVLRPAGQRDVAGGKTG-QGPGS-RAPSPRLPNKTISGPLIPPASPRL 152
+GGF P +R D G G + PG + SP LP P +P P L
Sbjct: 2317 GSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDL 2376
Query: 153 GNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPL 190
S+ H + A P P P P L
Sbjct: 2377 LLESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHL 2414
Score = 33.9 bits (76), Expect = 0.34
Identities = 39/150 (26%), Positives = 50/150 (33%), Gaps = 26/150 (17%)
Query: 73 IESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG------------- 119
+ S +G G G + PP L D+ P PA +R G
Sbjct: 141 LRSQRGRAPRGRGRKHKTTPLPPPRLADV--APTPPKTPARKRGEEGTERMVQALTELLR 198
Query: 120 -GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT 178
+ Q P SRA P P ++ P PA P +A A A P
Sbjct: 199 RAQAPQAPRSRACEPSTPRRSRGRPPGRPAGP-CRRKQQAVVVAEAAVTIPK-------- 249
Query: 179 PPPPPPPLPPPLPSSSPIKTPLVSPPGPLT 208
P PPPP+ P + K PGP T
Sbjct: 250 -PEPPPPVVPVKHQTGSWKCKEGPGPGPGT 278
Score = 32.0 bits (71), Expect = 1.3
Identities = 51/210 (24%), Positives = 75/210 (35%), Gaps = 26/210 (12%)
Query: 41 ADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGD 100
A+P +ALL + LR++ ++ + P+++ +G + G G +RG D
Sbjct: 59 AEPGEDTALLRLLGLRRGLRRLRRL--WAGPRVQRGRGRGR-GRGWGPSRGCVPEEESSD 115
Query: 101 LFAG-----GFPV---LRPAGQRDVAGGKTGQGPGSRA--------PSPRLPNKTISGPL 144
+ GF + P+ R + G+ P R P PRL + + P
Sbjct: 116 GESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPK 175
Query: 145 IPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP 204
P A R +E A T R AP P P P P + P
Sbjct: 176 TP-ARKRGEEGTERMVQALTELLR-RAQAPQAPRSRACEPSTPRRSRGRPPGR-----PA 228
Query: 205 GPLTKGNLPVVAPPVPCAPPPPPPPPPPTP 234
GP + VV P P PPPP P
Sbjct: 229 GPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
Score = 30.4 bits (67), Expect = 3.7
Identities = 40/155 (25%), Positives = 51/155 (32%), Gaps = 24/155 (15%)
Query: 223 PPPPPPPPPPTPPPLPPASVLSD--KAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPA 280
PPP PTPP P + + + L L P P C EP+
Sbjct: 162 PPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRAC-------EPS 214
Query: 281 SPAQDAQEP---PAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPP 337
+P + P PA P A A++ P E PPP+ P +
Sbjct: 215 TPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIP-------KPEPPPPVVPVKHQTGSWK 267
Query: 338 QKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGK 372
K G P P G Q R GR G G G+
Sbjct: 268 CKEGPGPGPGTPRRGG-----QSSRGGRGGRGRGR 297
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 112 bits (281), Expect = 6e-25
Identities = 74/205 (36%), Positives = 86/205 (41%), Gaps = 35/205 (17%)
Query: 186 LPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPC----APPPPPPPPPPTPPPLPPAS 241
+PP +PS +P+ PP P G+ + PP P PPPPPPPPP PPPLP
Sbjct: 563 VPPSVPSRAPV------PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 616
Query: 242 VLSDKAVKPQLAPLHLPP-------IPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPP 294
+S P + PP IPPP PL G P + P A PPP
Sbjct: 617 CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP------PPP 670
Query: 295 PLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGS 354
PLP A P P PPLPG PPPLP ++ PP G +P PP PG
Sbjct: 671 PLPGSARIPP----PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGG 726
Query: 355 QPFLQKKRHGRPGAGGGKLNPPPAP 379
G P G PPP P
Sbjct: 727 P--------GIPPPPPGMGMPPPPP 743
Score = 106 bits (265), Expect = 4e-23
Identities = 72/200 (36%), Positives = 77/200 (38%), Gaps = 34/200 (17%)
Query: 171 VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP 230
+ PP P PP PPLP S P PG T PPPPPPP
Sbjct: 561 ITVPPSVPSRAPVPP-APPLPGDSGTIIPPPPAPGDST--------------TPPPPPPP 605
Query: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPP-------IPPPLPLLPPCGYP-------GLK 276
PP PPPLP +S P + PP IPPP PL G P G
Sbjct: 606 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA 665
Query: 277 AEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336
P P + P PPPPLP A P P PPLPG PPPL P P P
Sbjct: 666 IPPPPPLPGSARIPPPPPPLPGSAGIPP----PPPPLPGEAGMPPPPPPL-PGGPGIPPP 720
Query: 337 PQKAGAQALPAPPAPPGSQP 356
P G +P PP G P
Sbjct: 721 PPFPGGPGIPPPPPGMGMPP 740
Score = 106 bits (265), Expect = 4e-23
Identities = 80/224 (35%), Positives = 91/224 (40%), Gaps = 49/224 (21%)
Query: 135 LPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSS 194
+P S +PPA P G++ G PP P PPP PPPPPP PPPLP
Sbjct: 563 VPPSVPSRAPVPPAPPLPGDS----GTIIPPPPAPGDSTTPPP--PPPPPPPPPPLPGGV 616
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPP--PLPPASVLSDKAVKPQL 252
I +P P G ++PP P + PPPPP P +P S L P
Sbjct: 617 CISSPPSLPGG-------TAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP 669
Query: 253 APL----HLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASL 308
PL +PP PPPLP G G+ P PPPPLP A P
Sbjct: 670 PPLPGSARIPPPPPPLP-----GSAGI--------------PPPPPPLPGEAGMPP---- 706
Query: 309 PAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPP 352
P PPLPG PPP P P PP G PP PP
Sbjct: 707 PPPPLPG--GPGIPPPPPFPGGPGIPPPPPGMG-----MPPPPP 743
Score = 79.3 bits (194), Expect = 7e-15
Identities = 64/195 (32%), Positives = 71/195 (36%), Gaps = 31/195 (15%)
Query: 211 NLPVVAPPVPCAPPPPPPPPPPTPPP------LPPASVLSDKAVKPQLAPLHLPPIPPPL 264
+L A VP + P P PP P P +PP D P P PP PPPL
Sbjct: 555 SLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPP--PPPPPPPL 612
Query: 265 P----LLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPA-------PPL 313
P + P PG A P PPPPLP +SLP PPL
Sbjct: 613 PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 672
Query: 314 PGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAP----PGSQPFLQKKRHGRPGAG 369
PG PPPLP + PP G +P PP P PG P P
Sbjct: 673 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPP--------PPPFP 724
Query: 370 GGKLNPPPAPPARSP 384
GG PPP P P
Sbjct: 725 GGPGIPPPPPGMGMP 739
Score = 75.9 bits (185), Expect = 8e-14
Identities = 84/266 (31%), Positives = 96/266 (36%), Gaps = 107/266 (40%)
Query: 2 PVPPPPPPP------LPPPP-------PPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSA 48
PVPP PP P +PPPP PP PPPPPP PP+ P G
Sbjct: 572 PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPP--PPL-----------PGG--- 615
Query: 49 LLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPV 108
+ S P + GG+A + PP GD P
Sbjct: 616 ----------------VCISSPPSLP---------GGTAI---SPPPPLSGDATIPPPPP 647
Query: 109 LRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPR 168
L +G G +PS LP G IPP P G+AR PP
Sbjct: 648 L-------------PEGVGIPSPS-SLP----GGTAIPPPPP-------LPGSARIPPPP 682
Query: 169 PNVPAPPPPTPPPPP-------PPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPC 221
P +P PPPPP PP PPPLP P + PP P G P
Sbjct: 683 PPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGG-----PGIPPPPPFPGG---------PG 728
Query: 222 APPPPP----PPPPPTPPPLPPASVL 243
PPPPP PPPPP +P A VL
Sbjct: 729 IPPPPPGMGMPPPPPFGFGVPAAPVL 754
Score = 70.9 bits (172), Expect = 2e-12
Identities = 64/187 (34%), Positives = 74/187 (39%), Gaps = 37/187 (19%)
Query: 95 PPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGP----GSRAPSPRLP---NKTISGPLIPP 147
PP GD P P + GG P G A SP P + TI P PP
Sbjct: 590 PPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP--PP 647
Query: 148 ASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP-----PPPPPPLP-----PPLPSSSPIK 197
+G S + TA P PPPP P PPPPPPLP PP P P +
Sbjct: 648 LPEGVGIPSPSSLPGGTAIP------PPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE 701
Query: 198 TPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP----PPTPP--------PLPPASVLSD 245
+ PP PL G PP P P PPPPP PP PP P+ P +
Sbjct: 702 AGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPK 761
Query: 246 KAVKPQL 252
K KP++
Sbjct: 762 KLYKPEV 768
Score = 42.0 bits (97), Expect = 0.001
Identities = 34/114 (29%), Positives = 42/114 (36%), Gaps = 26/114 (22%)
Query: 293 PPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPP 352
PP +P A P APPLPG + + PPP P G P PP PP
Sbjct: 564 PPSVPSRAPVPP-----APPLPGDSGTIIPPPPAP-------------GDSTTPPPPPPP 605
Query: 353 GSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGG 406
P P GG ++ PP+ P + + S AT P P G
Sbjct: 606 PPPP--------PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG 651
Score = 35.0 bits (79), Expect = 0.15
Identities = 14/27 (51%), Positives = 15/27 (55%)
Query: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAP 29
+PPPPP PPPPP G P P P
Sbjct: 729 IPPPPPGMGMPPPPPFGFGVPAAPVLP 755
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 112 bits (281), Expect = 6e-25
Identities = 74/205 (36%), Positives = 86/205 (41%), Gaps = 35/205 (17%)
Query: 186 LPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPC----APPPPPPPPPPTPPPLPPAS 241
+PP +PS +P+ PP P G+ + PP P PPPPPPPPP PPPLP
Sbjct: 572 VPPSVPSRAPV------PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 625
Query: 242 VLSDKAVKPQLAPLHLPP-------IPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPP 294
+S P + PP IPPP PL G P + P A PPP
Sbjct: 626 CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIP------PPP 679
Query: 295 PLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGS 354
PLP A P P PPLPG PPPLP ++ PP G +P PP PG
Sbjct: 680 PLPGSARIPP----PPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGG 735
Query: 355 QPFLQKKRHGRPGAGGGKLNPPPAP 379
G P G PPP P
Sbjct: 736 P--------GIPPPPPGMGMPPPPP 752
Score = 106 bits (265), Expect = 4e-23
Identities = 72/200 (36%), Positives = 77/200 (38%), Gaps = 34/200 (17%)
Query: 171 VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP 230
+ PP P PP PPLP S P PG T PPPPPPP
Sbjct: 570 ITVPPSVPSRAPVPP-APPLPGDSGTIIPPPPAPGDST--------------TPPPPPPP 614
Query: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPP-------IPPPLPLLPPCGYP-------GLK 276
PP PPPLP +S P + PP IPPP PL G P G
Sbjct: 615 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTA 674
Query: 277 AEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336
P P + P PPPPLP A P P PPLPG PPPL P P P
Sbjct: 675 IPPPPPLPGSARIPPPPPPLPGSAGIPP----PPPPLPGEAGMPPPPPPL-PGGPGIPPP 729
Query: 337 PQKAGAQALPAPPAPPGSQP 356
P G +P PP G P
Sbjct: 730 PPFPGGPGIPPPPPGMGMPP 749
Score = 106 bits (265), Expect = 4e-23
Identities = 80/224 (35%), Positives = 91/224 (40%), Gaps = 49/224 (21%)
Query: 135 LPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSS 194
+P S +PPA P G++ G PP P PPP PPPPPP PPPLP
Sbjct: 572 VPPSVPSRAPVPPAPPLPGDS----GTIIPPPPAPGDSTTPPP--PPPPPPPPPPLPGGV 625
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPP--PLPPASVLSDKAVKPQL 252
I +P P G ++PP P + PPPPP P +P S L P
Sbjct: 626 CISSPPSLPGG-------TAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP 678
Query: 253 APL----HLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASL 308
PL +PP PPPLP G G+ P PPPPLP A P
Sbjct: 679 PPLPGSARIPPPPPPLP-----GSAGI--------------PPPPPPLPGEAGMPP---- 715
Query: 309 PAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPP 352
P PPLPG PPP P P PP G PP PP
Sbjct: 716 PPPPLPG--GPGIPPPPPFPGGPGIPPPPPGMG-----MPPPPP 752
Score = 79.3 bits (194), Expect = 7e-15
Identities = 64/195 (32%), Positives = 71/195 (36%), Gaps = 31/195 (15%)
Query: 211 NLPVVAPPVPCAPPPPPPPPPPTPPP------LPPASVLSDKAVKPQLAPLHLPPIPPPL 264
+L A VP + P P PP P P +PP D P P PP PPPL
Sbjct: 564 SLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPP--PPPPPPPL 621
Query: 265 P----LLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPA-------PPL 313
P + P PG A P PPPPLP +SLP PPL
Sbjct: 622 PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 681
Query: 314 PGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAP----PGSQPFLQKKRHGRPGAG 369
PG PPPLP + PP G +P PP P PG P P
Sbjct: 682 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPP--------PPPFP 733
Query: 370 GGKLNPPPAPPARSP 384
GG PPP P P
Sbjct: 734 GGPGIPPPPPGMGMP 748
Score = 75.9 bits (185), Expect = 8e-14
Identities = 84/266 (31%), Positives = 96/266 (36%), Gaps = 107/266 (40%)
Query: 2 PVPPPPPPP------LPPPP-------PPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSA 48
PVPP PP P +PPPP PP PPPPPP PP+ P G
Sbjct: 581 PVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPP--PPL-----------PGG--- 624
Query: 49 LLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPV 108
+ S P + GG+A + PP GD P
Sbjct: 625 ----------------VCISSPPSLP---------GGTAI---SPPPPLSGDATIPPPPP 656
Query: 109 LRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPR 168
L +G G +PS LP G IPP P G+AR PP
Sbjct: 657 L-------------PEGVGIPSPS-SLP----GGTAIPPPPP-------LPGSARIPPPP 691
Query: 169 PNVPAPPPPTPPPPP-------PPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPC 221
P +P PPPPP PP PPPLP P + PP P G P
Sbjct: 692 PPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGG-----PGIPPPPPFPGG---------PG 737
Query: 222 APPPPP----PPPPPTPPPLPPASVL 243
PPPPP PPPPP +P A VL
Sbjct: 738 IPPPPPGMGMPPPPPFGFGVPAAPVL 763
Score = 70.9 bits (172), Expect = 2e-12
Identities = 64/187 (34%), Positives = 74/187 (39%), Gaps = 37/187 (19%)
Query: 95 PPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGP----GSRAPSPRLP---NKTISGPLIPP 147
PP GD P P + GG P G A SP P + TI P PP
Sbjct: 599 PPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP--PP 656
Query: 148 ASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP-----PPPPPPLP-----PPLPSSSPIK 197
+G S + TA P PPPP P PPPPPPLP PP P P +
Sbjct: 657 LPEGVGIPSPSSLPGGTAIP------PPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE 710
Query: 198 TPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP----PPTPP--------PLPPASVLSD 245
+ PP PL G PP P P PPPPP PP PP P+ P +
Sbjct: 711 AGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPK 770
Query: 246 KAVKPQL 252
K KP++
Sbjct: 771 KLYKPEV 777
Score = 42.0 bits (97), Expect = 0.001
Identities = 34/114 (29%), Positives = 42/114 (36%), Gaps = 26/114 (22%)
Query: 293 PPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPP 352
PP +P A P APPLPG + + PPP P G P PP PP
Sbjct: 573 PPSVPSRAPVPP-----APPLPGDSGTIIPPPPAP-------------GDSTTPPPPPPP 614
Query: 353 GSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGG 406
P P GG ++ PP+ P + + S AT P P G
Sbjct: 615 PPPP--------PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG 660
Score = 35.0 bits (79), Expect = 0.15
Identities = 14/27 (51%), Positives = 15/27 (55%)
Query: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAP 29
+PPPPP PPPPP G P P P
Sbjct: 738 IPPPPPGMGMPPPPPFGFGVPAAPVLP 764
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 112 bits (281), Expect = 6e-25
Identities = 103/305 (33%), Positives = 119/305 (39%), Gaps = 66/305 (21%)
Query: 128 SRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT-------PP 180
S+ SP L GP SP+ GN + PP P P PPP PP
Sbjct: 24 SQEESPSLIAGNPQGP-----SPQGGNKPQG------PPPPPGKPQGPPPQGGNKPQGPP 72
Query: 181 PPPPPLPPPLPSSSPIKTPLVSPPG-----PLTKGNLPVVAPPVPCAPPPPPP------- 228
PP P PP P ++P SPPG P GN P PP P P PPP
Sbjct: 73 PPGKPQGPP-PQGDKSRSPR-SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQ 130
Query: 229 -PPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA-QDA 286
PPPP P PP DK+ P+ +P P PPP P G P +P P Q
Sbjct: 131 GPPPPGKPQGPPPQ--GDKSRSPR-SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 187
Query: 287 QEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALP 346
++P PPPP P PP G S S PP P+ P PPQ G
Sbjct: 188 KKPQGPPPPGKPQG----------PPPQGDKSRSSQSPPGKPQGP----PPQ--GGNQPQ 231
Query: 347 APPAPPGSQPFLQKKRHGRPGAGGGKLNPPP------APPARSPTTELSSKSQQATAWTP 400
PP PPG K G P GG K PP PPA+ + S++S P
Sbjct: 232 GPPPPPG-------KPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGP 284
Query: 401 TQQPG 405
QQ G
Sbjct: 285 PQQEG 289
Score = 105 bits (262), Expect = 9e-23
Identities = 111/333 (33%), Positives = 124/333 (37%), Gaps = 65/333 (19%)
Query: 71 PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRA 130
PQ S +G NK G PP G G P P G+ G QG SR
Sbjct: 36 PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQ---GPPPQGDKSR- 88
Query: 131 PSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT-------PPPPP 183
SPR P GP P+ GN + PP P P PPP PPPP
Sbjct: 89 -SPRSPPGKPQGP-----PPQGGNQPQG------PPPPPGKPQGPPPQGGNRPQGPPPPG 136
Query: 184 PPLPPPLPSSSPIKTPLVSPPG-----PLTKGNLPVVAPPVPCAPPPPPP--------PP 230
P PP P ++P SPPG P GN P PP P P PPP PP
Sbjct: 137 KPQGPP-PQGDKSRSPR-SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP 194
Query: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA-QDAQEP 289
PP P PP DK+ Q +P P PPP P G P +P P Q +P
Sbjct: 195 PPGKPQGPPPQ--GDKSRSSQ-SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 251
Query: 290 PAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSP------SFQAPPQKAGAQ 343
PPPP P P G S S PP P+ P + Q PP AG
Sbjct: 252 QGPPPPGKPQGP---------PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGN 302
Query: 344 ALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPP 376
P APP QP + RP GG PP
Sbjct: 303 P-QQPQAPPAGQP----QGPPRPPQGGRPSRPP 330
Score = 90.5 bits (223), Expect = 3e-18
Identities = 104/361 (28%), Positives = 121/361 (33%), Gaps = 101/361 (27%)
Query: 2 PVPPPPPPPLPPPPP--------------PLGAPPPPPPSAPPVSTDTSSLRRADPKGRS 47
P P P PPPP P G PPP P PP D S R+ P
Sbjct: 39 PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP---- 94
Query: 48 ALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFP 107
PQ +G N+ G PP G G P
Sbjct: 95 ---------------------GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP 133
Query: 108 VLRPAGQRDVAGGKTGQGP---GSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAART 164
P G+ QGP G ++ SPR P GP P+ GN +
Sbjct: 134 ---PPGK--------PQGPPPQGDKSRSPRSPPGKPQGP-----PPQGGNQPQG------ 171
Query: 165 APPRPNVPAPPPPT-------PPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAP 217
PP P P PPP PPPP P PP P ++ SPPG P P
Sbjct: 172 PPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP-PQGDKSRSS-QSPPGK------PQGPP 223
Query: 218 PVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKA 277
P P PPPPP P PP KPQ P PP P PP A
Sbjct: 224 PQGGNQPQGPPPPPGKPQGPPPQG-----GNKPQ------GPPPPGKPQGPP-------A 265
Query: 278 EPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPP 337
+ S +Q A+ PP P P +P+ P PP G + PP P+ P PP
Sbjct: 266 QGGSKSQSARSPPGKPQGPPQQEGNNPQG--PPPPAGGNPQQPQAPPAGQPQGP--PRPP 321
Query: 338 Q 338
Q
Sbjct: 322 Q 322
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 110 bits (275), Expect = 3e-24
Identities = 107/353 (30%), Positives = 125/353 (35%), Gaps = 95/353 (26%)
Query: 159 HGAARTAP-PRPNVPAPPPPTPPPPPPPL------PPPLPSSSPIKTP--LVSPPGPLTK 209
H + AP P P P PPP PPPPPPP PPP P S P + + S P P
Sbjct: 743 HQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIA 802
Query: 210 GNLPVVAP--------------------PVPCAPPP-PPPPPPPTPPPLPPASVLSDKAV 248
+PV+ P P P PP P PP TPP L +V+S A+
Sbjct: 803 TQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPAL 862
Query: 249 KPQLA-----PLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPA-----PPPPLPP 298
L P + PP P PP P L P P +PP PP PP
Sbjct: 863 HNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPP 922
Query: 299 YASCSPRASL--------PAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQAL---PA 347
S + L P P LP V S+ PPPLPP PP + Q L P
Sbjct: 923 LTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPP-------PPHPSVQQQLQQQPP 975
Query: 348 PPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQAT---AWTPTQQP 404
PP PP QP Q++ PPP P P + S+ QQ P P
Sbjct: 976 PPPPPQPQPPPQQQHQ-----------PPPRPVHLQPM-QFSTHIQQPPPPQGQQPPHPP 1023
Query: 405 GGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPGPW 457
GQ PPP KP Q I PR P+
Sbjct: 1024 PGQQP----------------------PPPQPAKPQQVIQHHHSPRHHKSDPY 1054
Score = 93.6 bits (231), Expect = 4e-19
Identities = 111/383 (28%), Positives = 136/383 (35%), Gaps = 92/383 (24%)
Query: 2 PVP--PPPPPPLPPPPPP-----LGAPPPPPPSAP----------PVSTDTSSLRRADPK 44
PVP PPPPP PPPPPP PPPPPPS P P + + +P+
Sbjct: 752 PVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQ 811
Query: 45 GRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAG 104
++ I T+ I P++ E STPP L
Sbjct: 812 LPGSVFDPIGHFTQ-----PILHLPQPELPPHLPQPPE---------HSTPPHLNQHAVV 857
Query: 105 GFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPA-SPRLGNTSEAHGAAR 163
P L A + + P +RA + LP K P PPA SP L T
Sbjct: 858 SPPALHNALPQQPS------RPSNRAAA--LPPK----PARPPAVSPALTQTPLLPQPPM 905
Query: 164 TAPPRPNVPAPPPPTPP----------------PPPPPLPPPLPSSSPIKTPLVSPPGPL 207
PP+ + PP PP PP PL P + S PL PP P
Sbjct: 906 AQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPS 965
Query: 208 TKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLL 267
+ L PP PPPP P PPP PP + ++P H+ PPP
Sbjct: 966 VQQQLQQQPPP----PPPPQPQPPPQQQHQPPPRPVH---LQPMQFSTHIQQPPPPQGQQ 1018
Query: 268 PPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYA---SCSPRASLPAPPLPGVNSSSETPP 324
PP PG Q+PP P P P SPR P G E P
Sbjct: 1019 PPHPPPG------------QQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTG--HLREAPS 1064
Query: 325 PLPPKSP--------SFQAPPQK 339
PL SP + Q+PPQ+
Sbjct: 1065 PLMIHSPQMSQFQSLTHQSPPQQ 1087
Score = 76.6 bits (187), Expect = 5e-14
Identities = 105/417 (25%), Positives = 145/417 (34%), Gaps = 57/417 (13%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKG----------RSALLA 51
P PPPP P P +PPP + PV DP G + L
Sbjct: 778 PPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPP 837
Query: 52 DIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRP 111
+ Q +N + + + + R A+ PP +P
Sbjct: 838 HLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPP-------------KP 884
Query: 112 AGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAH--GAARTAPPRP 169
A V+ T Q P P P + + PPA P + + + PP P
Sbjct: 885 ARPPAVSPALT-QTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTP 943
Query: 170 NVPA------PPPPTPPPP-----------PPPLPPPLPSSSPIKTPLVSPPGPL----T 208
+P+ PPPP PPPP PPP PPP P P + PP P+
Sbjct: 944 LLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPP-QQQHQPPPRPVHLQPM 1002
Query: 209 KGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLP 268
+ + + PP P PP PPP PPP PA + ++ +P H P L
Sbjct: 1003 QFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAK--PQQVIQHHHSPRHHKSDPYSTGHLR 1060
Query: 269 PCGYPGLKAEP-ASPAQDAQEPPAPPPPLPPYASCSPRASLPAP-PLPGVNSSSETPPPL 326
P + P S Q P + P AS+ P PL V P +
Sbjct: 1061 EAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPII 1120
Query: 327 --PPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLN-PPPAPP 380
P SPS + P K +++ AP P +P ++ GRP + N PPP P
Sbjct: 1121 RSEPFSPSLRPEPPK-HPESIKAPVHLP-QRPEMKPVDVGRPVIRPPEQNAPPPGAP 1175
Score = 70.1 bits (170), Expect = 4e-12
Identities = 53/167 (31%), Positives = 71/167 (42%), Gaps = 34/167 (20%)
Query: 147 PASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGP 206
P + NT++A +T P+PN PP P P P + P L +P+ T V PP P
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPN--PPPVQATPHPFPAVTPDLIVQTPVMT--VVPPQP 246
Query: 207 LTKGNLPVVAPPVPCAPPPPPPPPPPTPPPL---PPASVLSDKAVKPQ------------ 251
L PPVP P P PPP P P P+ PP + + VK +
Sbjct: 247 LQ------TPPPVP---PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
Query: 252 --LAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQ----DAQEPPAP 292
+ P+H PP PP P G + P P + D+Q+ PAP
Sbjct: 298 TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
Score = 51.2 bits (121), Expect = 2e-06
Identities = 63/266 (23%), Positives = 91/266 (34%), Gaps = 37/266 (13%)
Query: 3 VPPPPPPPLPPPPPP------LGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQG 56
V PPPPLPPPP P PPPPPP P ++ P R L +Q
Sbjct: 950 VQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQP----QPPPQQQHQPPPRPVHLQPMQFS 1005
Query: 57 TRLRKVTQINDRSAPQ---------IESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFP 107
T +++ + P + +K + S P + G L P
Sbjct: 1006 THIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSP 1065
Query: 108 VLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPP 167
++ + Q T Q P + P+ + + ++ P + + H +P
Sbjct: 1066 LMIHSPQMSQFQSLTHQSPPQQNVQPK-KQELRAASVVQPQPLVVVKEEKIH-----SPI 1119
Query: 168 RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKG---NLPVVAPPVPCAPP 224
+ P P P PP P IK P+ P P K PV+ PP APP
Sbjct: 1120 IRSEPFSPSLRPEPPKHP--------ESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPP 1171
Query: 225 P-PPPPPPPTPPPLPPASVLSDKAVK 249
P P P P + D +K
Sbjct: 1172 PGAPDKDKQKQEPKTPVAPKKDLKIK 1197
Score = 50.1 bits (118), Expect = 5e-06
Identities = 79/348 (22%), Positives = 111/348 (31%), Gaps = 55/348 (15%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
+P P PP + P P PP + PP + D + + L +Q L+
Sbjct: 880 LPPKPARPPAVSPALTQTPLLPQPPMAQPP------QVLLEDEEPPAPPLTSMQMQLYLQ 933
Query: 61 KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG 120
++ ++ P + S K S PP P L P V
Sbjct: 934 QLQKVQP-PTPLLPSVK-------------VQSQPP----------PPLPPPPHPSVQQQ 969
Query: 121 KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP 180
Q P P P+ P + P PP L + + PP+ P PPP
Sbjct: 970 LQQQPPPPPPPQPQPPPQQQHQP--PPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQ 1027
Query: 181 PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP------------PPPP 228
PPPP P +P P + G+L P+ P PP
Sbjct: 1028 PPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQ 1087
Query: 229 PPPPTPPPLPPASVLSDK-AVKPQLAPLHLP-----PIPPPLPLLPPCGYPGLKAEPASP 282
P L ASV+ + V + +H P P P L PP +KA P
Sbjct: 1088 NVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKA----P 1143
Query: 283 AQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETP-PPLPPK 329
Q P P + P + P P P + + P P+ PK
Sbjct: 1144 VHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPK 1191
Score = 48.9 bits (115), Expect = 1e-05
Identities = 48/176 (27%), Positives = 64/176 (36%), Gaps = 35/176 (19%)
Query: 204 PGPLTKGNLPVVA-PPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQL-APLHLPPIP 261
PG T N + PP P P PPP TP P P AV P L + +
Sbjct: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFP--------AVTPDLIVQTPVMTVV 242
Query: 262 PPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSE 321
PP PL P P P +PA P P PP + +P+ P GV ++
Sbjct: 243 PPQPLQTPPPVPPQPQPPPAPA------PQPVQSHPPIIAATPQ---PVKTKKGVKRKAD 293
Query: 322 T-----------PPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRP 366
T PP LPP+ + K G + + P P + ++H P
Sbjct: 294 TTTPTTIDPIHEPPSLPPEPKT-----TKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
Score = 36.6 bits (83), Expect = 0.052
Identities = 21/55 (38%), Positives = 22/55 (40%), Gaps = 13/55 (23%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAP-------------PVSTDTSSLRRAD 42
M V PP P PPP PP PPP P P PV T R+AD
Sbjct: 239 MTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKAD 293
Score = 32.7 bits (73), Expect = 0.75
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 8/88 (9%)
Query: 1 MPVPPPPP-----PPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQ 55
MP P P P PPP + APP S+ S+D+ S + R+ LA++Q+
Sbjct: 457 MPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQE 516
Query: 56 GTRLRKV-TQINDRSAPQIESSKGTNKE 82
+L+ V Q+ S PQ K K+
Sbjct: 517 --QLKAVHEQLAALSQPQQNKPKKKEKD 542
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 105 bits (262), Expect = 9e-23
Identities = 101/382 (26%), Positives = 131/382 (34%), Gaps = 58/382 (15%)
Query: 4 PPPP------PPPLPPPPPPLGAPPPPPP---SAPPVSTDTSSLRRADPKGRSALLADIQ 54
P PP PPP P PP+ PPP +PP+ST T+ P
Sbjct: 1422 PSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTP----------- 1470
Query: 55 QGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQ 114
S P S T + T + PPT P+ PA
Sbjct: 1471 --------------SPPTTTPSPPTTTPSPPTTTT--TTPPPTTTPSPPTTTPITPPAST 1514
Query: 115 RDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAP 174
+ T P + +P P T S P P +P T+ T P P
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPP-PTTTPSPPTTTPITPPTSTTTLP--PTTTPSPPPTTTTT 1571
Query: 175 PPPTPPPPPP----PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPP- 229
PPPT P PP P PP + +++P T SPP T P P P P PP
Sbjct: 1572 PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1631
Query: 230 ----PPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPP--PLPLLPPCGYPG--LKAEPAS 281
PP T P PP + + P P PP PP P + P+
Sbjct: 1632 TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSP 1691
Query: 282 PAQDAQEP-PAPPPPLPPYASCSPRA-SLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQK 339
P P P P P + +P + + P+PP + + S T P PP + PP
Sbjct: 1692 PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTT 1751
Query: 340 AGA--QALPAPPA--PPGSQPF 357
+ P PP+ PP PF
Sbjct: 1752 TSSPLTTTPLPPSITPPTFSPF 1773
Score = 97.4 bits (241), Expect = 2e-20
Identities = 79/300 (26%), Positives = 98/300 (32%), Gaps = 24/300 (8%)
Query: 122 TGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPP 181
T P + PSP + T P P+ P T+ + P PP TP P
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456
Query: 182 P------PPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPP 235
P PPP P P ++ P +P P T P P P PP P TPP
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTT-----TTTTPPPTTTPSPPTTTPITPP 1511
Query: 236 ----PLPPASVLSDKAVKPQLAPLHLPPIPP-PLPLLPPCGYPGL--KAEPASPAQDAQE 288
LPP + S P P PP P+ PP L P+ P
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1571
Query: 289 PPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAP 348
PP P P P + P+PP + T P PP + + PP + P
Sbjct: 1572 PPPTTTPSP------PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1625
Query: 349 PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQL 408
PP S L P PP P+ TT S T PT P +
Sbjct: 1626 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPI 1685
Score = 97.1 bits (240), Expect = 3e-20
Identities = 88/311 (28%), Positives = 109/311 (35%), Gaps = 62/311 (19%)
Query: 126 PGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPP--- 182
P + PSP + T P P SP + T T PP P+PP TP PP
Sbjct: 1433 PPTTTPSPPITTTTTPPPTTTP-SPPISTT--------TTPPPTTTPSPPTTTPSPPTTT 1483
Query: 183 --PP----PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVP-----CAPPPPPPPPP 231
PP PPP + SP T ++PP T LP P P PPP P P
Sbjct: 1484 PSPPTTTTTTPPPTTTPSPPTTTPITPPASTT--TLPPTTTPSPPTTTTTTPPPTTTPSP 1541
Query: 232 PTPPPL-PPASVLSDKAVKPQLAPLHLPPIPPPLPLLPP---CGYPGLKAEPASPAQDAQ 287
PT P+ PP S + L P P PP PP P P+ P
Sbjct: 1542 PTTTPITPPTSTTT-------LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTT 1594
Query: 288 EPP---APPPPL------PPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQ 338
PP P PP PP + SP + P P + T P PP + + PP
Sbjct: 1595 TPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1654
Query: 339 KAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP-TTELSSKSQQATA 397
+ P+PP + PPP SP TT S + T
Sbjct: 1655 TTPSPPTTTTPSPPITT----------------TTTPPPTTTPSSPITTTPSPPTTTMTT 1698
Query: 398 WTPTQQPGGQL 408
+PT P +
Sbjct: 1699 PSPTTTPSSPI 1709
Score = 79.7 bits (195), Expect = 5e-15
Identities = 86/349 (24%), Positives = 104/349 (29%), Gaps = 87/349 (24%)
Query: 2 PVPPP------PPPPLPPPPPPLGAPPPP-----PPSAPPVSTDTSSLRRADPKGRSALL 50
P+ PP PP P PP PPP PP+ P++ TS+
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST------------- 1553
Query: 51 ADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLR 110
T L T +P ++ S T +PPT+
Sbjct: 1554 ------TTLPPTT----TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTI------------ 1591
Query: 111 PAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPN 170
T P + PSP T P P+ P PP
Sbjct: 1592 ----------TTTTPPPTTTPSPPTTTTTTPPPTTTPSPPT---------TTPITPPTST 1632
Query: 171 VPAPPPPTPPPPP--PPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPP 228
PP TP PPP PPP + SP T SPP T P P P P PP
Sbjct: 1633 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPP 1692
Query: 229 PPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQE 288
T P P + S P PPP + P SP
Sbjct: 1693 TTTMTTP--SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP-----------SPTTTPSP 1739
Query: 289 PPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPP 337
P LPP + SP + P PP S TPP P S + P
Sbjct: 1740 PTTTMTTLPPTTTSSPLTTTPLPP-------SITPPTFSPFSTTTPTTP 1781
Score = 68.9 bits (167), Expect = 9e-12
Identities = 54/196 (27%), Positives = 69/196 (35%), Gaps = 28/196 (14%)
Query: 217 PPVPCAPPPPPPPPPPTPPP-----LPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCG 271
P C P PP P+PPP LPP + S P PP P P +
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPS----PPTTTTTTPPPTTTPSPPITTTT 1446
Query: 272 YPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSP 331
P P+ P PP P PP + SP + P+PP +++ TPPP SP
Sbjct: 1447 TPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPP----TTTTTTPPPTTTPSP 1502
Query: 332 SFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPP---PAPPARSPTTEL 388
P PP S L P PP P+PP +P T
Sbjct: 1503 ------------PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1550
Query: 389 SSKSQQATAWTPTQQP 404
+S + TP+ P
Sbjct: 1551 TSTTTLPPTTTPSPPP 1566
Score = 61.6 bits (148), Expect = 2e-09
Identities = 69/283 (24%), Positives = 87/283 (30%), Gaps = 41/283 (14%)
Query: 2 PVPPPPPPPLPP------PPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQ 55
P PP P PP PP +PPP + PP +T S P +
Sbjct: 1539 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPP 1598
Query: 56 GTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR 115
T T P S T +T + PPT P P
Sbjct: 1599 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST--TTLPPTTT-------PSPPPTTTT 1649
Query: 116 DVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPR--PNVPA 173
T P + PSP + T P P+SP S T P P+ P
Sbjct: 1650 TPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPI 1709
Query: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP--PPPPPPP 231
TP P PPP ++P +P +P P T PP + P P PP
Sbjct: 1710 TTTTTPSSTTTPSPPPTTMTTP--SPTTTPSPPTT---TMTTLPPTTTSSPLTTTPLPPS 1764
Query: 232 PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPG 274
TPP P S + P P +P C + G
Sbjct: 1765 ITPPTFSPFSTTT-----------------PTTPCVPLCNWTG 1790
Score = 59.7 bits (143), Expect = 6e-09
Identities = 66/286 (23%), Positives = 88/286 (30%), Gaps = 60/286 (20%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 4071 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4130
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAVK 249
PI T P P G P+ P P P PT P+ + ++
Sbjct: 4131 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT----- 4185
Query: 250 PQLAPLHLPPIPPPLPLLPPCGYP-GLKAEPASPAQDAQEPPAPPPPLPPYASCSP---R 305
P P P G P P + + PP P ++ SP
Sbjct: 4186 -----------PTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES 4234
Query: 306 ASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGR 365
+L + P + +S PP P AP +G L PP+ S
Sbjct: 4235 TTLLSTLPPAIEMTSTAPPSTP------TAPTTTSGGHTLSPPPSTTTS----------- 4277
Query: 366 PGAGGGKLNPPPAPPARSPTTELSSKSQQAT-------AWTPTQQP 404
PP P R TT SS +T AWTPT P
Sbjct: 4278 ----------PPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313
Score = 51.2 bits (121), Expect = 2e-06
Identities = 84/413 (20%), Positives = 120/413 (29%), Gaps = 51/413 (12%)
Query: 23 PPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKE 82
P PP+ P++T T+ P G T + T + P + T
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1947
Query: 83 GGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISG 142
+ T TP G P+ V T G + +P T++
Sbjct: 1948 ---TTTTTVTPTPTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTP 2001
Query: 143 PLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP-------PPPPPPLPPPLPSSSP 195
P + T T P P P TP P P P P+++P
Sbjct: 2002 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2061
Query: 196 IKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV-- 248
I T P P G P+ P P P PT P+ + ++
Sbjct: 2062 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2121
Query: 249 ---KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYAS 301
P P+ P P P G P + P P P P +
Sbjct: 2122 GTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2179
Query: 302 CSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGS 354
+ P P P +++ TP P P + + P P P P G+
Sbjct: 2180 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGT 2238
Query: 355 QPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
Q P + P P P ++PTT + T TPT P G
Sbjct: 2239 Q-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 2283
Score = 50.1 bits (118), Expect = 5e-06
Identities = 92/442 (20%), Positives = 133/442 (30%), Gaps = 57/442 (12%)
Query: 5 PPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQ 64
P PPP P P P PP + + T+S P + L I T T
Sbjct: 1721 PSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTS----SPLTTTPLPPSITPPTFSPFSTT 1776
Query: 65 INDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPV---LRPAGQRDVAGGK 121
+ + G G + + G T +GD+ G+ R DV G+
Sbjct: 1777 TPTTPCVPLCNWTGWLDSGKPNFHKPGGDTE-LIGDVCGPGWAANISCRATMYPDVPIGQ 1835
Query: 122 TGQG-----------------PGSRAPSPRLPNKTISGPL---IPPASPRLGNTSEAHGA 161
GQ PG P N I+ + + T+E
Sbjct: 1836 LGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTP 1895
Query: 162 ARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPC 221
T P P PTP P P+ +++ + TP +P G T P+
Sbjct: 1896 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVT 1954
Query: 222 APPPPPPPPPPTPPPLPPASVLSDKAV-----KPQLAPLHLPPIPPPLPLLPPCGYPGLK 276
P P PT P+ + ++ P P+ P P P G
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPT 2012
Query: 277 AEPASPAQDAQEPPAP----PPPLPPYASCSPRASLPAP-------PLPGVNSSSETPPP 325
P + P P P P + + P P P +++ TP P
Sbjct: 2013 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2072
Query: 326 LPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSP 384
P + + P P P P G+Q P + P P P ++P
Sbjct: 2073 TPTGTQTPTTTPITTTTTVTPT-PTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTP 2126
Query: 385 TTELSSKSQQATAWTPTQQPGG 406
TT + T TPT P G
Sbjct: 2127 TT---TPITTTTTVTPTPTPTG 2145
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/294 (21%), Positives = 89/294 (30%), Gaps = 34/294 (11%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 2047 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2106
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV- 248
PI T P P G P+ P P P PT P+ + ++
Sbjct: 2107 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2166
Query: 249 ----KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
P P+ P P P G P + P P P P
Sbjct: 2167 TGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224
Query: 301 SCSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
+ + P P P +++ TP P P + + P P P P G
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 2283
Query: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
+Q P + P P P ++PTT + T TPT P G
Sbjct: 2284 TQ-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 2329
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/294 (21%), Positives = 89/294 (30%), Gaps = 34/294 (11%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2290
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV- 248
PI T P P G P+ P P P PT P+ + ++
Sbjct: 2291 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2350
Query: 249 ----KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
P P+ P P P G P + P P P P
Sbjct: 2351 TGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408
Query: 301 SCSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
+ + P P P +++ TP P P + + P P P P G
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 2467
Query: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
+Q P + P P P ++PTT + T TPT P G
Sbjct: 2468 TQ-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 2513
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/294 (21%), Positives = 89/294 (30%), Gaps = 34/294 (11%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 2415 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2474
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV- 248
PI T P P G P+ P P P PT P+ + ++
Sbjct: 2475 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2534
Query: 249 ----KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
P P+ P P P G P + P P P P
Sbjct: 2535 TGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592
Query: 301 SCSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
+ + P P P +++ TP P P + + P P P P G
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 2651
Query: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
+Q P + P P P ++PTT + T TPT P G
Sbjct: 2652 TQ-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 2697
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/294 (21%), Positives = 89/294 (30%), Gaps = 34/294 (11%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2658
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV- 248
PI T P P G P+ P P P PT P+ + ++
Sbjct: 2659 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2718
Query: 249 ----KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
P P+ P P P G P + P P P P
Sbjct: 2719 TGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2776
Query: 301 SCSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
+ + P P P +++ TP P P + + P P P P G
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 2835
Query: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
+Q P + P P P ++PTT + T TPT P G
Sbjct: 2836 TQ-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 2881
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/294 (21%), Positives = 89/294 (30%), Gaps = 34/294 (11%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2842
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV- 248
PI T P P G P+ P P P PT P+ + ++
Sbjct: 2843 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2902
Query: 249 ----KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
P P+ P P P G P + P P P P
Sbjct: 2903 TGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960
Query: 301 SCSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
+ + P P P +++ TP P P + + P P P P G
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 3019
Query: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
+Q P + P P P ++PTT + T TPT P G
Sbjct: 3020 TQ-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 3065
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/294 (21%), Positives = 89/294 (30%), Gaps = 34/294 (11%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3026
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV- 248
PI T P P G P+ P P P PT P+ + ++
Sbjct: 3027 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3086
Query: 249 ----KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
P P+ P P P G P + P P P P
Sbjct: 3087 TGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144
Query: 301 SCSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
+ + P P P +++ TP P P + + P P P P G
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 3203
Query: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
+Q P + P P P ++PTT + T TPT P G
Sbjct: 3204 TQ-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 3249
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/294 (21%), Positives = 89/294 (30%), Gaps = 34/294 (11%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 3151 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3210
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV- 248
PI T P P G P+ P P P PT P+ + ++
Sbjct: 3211 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3270
Query: 249 ----KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
P P+ P P P G P + P P P P
Sbjct: 3271 TGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328
Query: 301 SCSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
+ + P P P +++ TP P P + + P P P P G
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 3387
Query: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
+Q P + P P P ++PTT + T TPT P G
Sbjct: 3388 TQ-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 3433
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/294 (21%), Positives = 89/294 (30%), Gaps = 34/294 (11%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 3335 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3394
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV- 248
PI T P P G P+ P P P PT P+ + ++
Sbjct: 3395 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3454
Query: 249 ----KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
P P+ P P P G P + P P P P
Sbjct: 3455 TGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3512
Query: 301 SCSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
+ + P P P +++ TP P P + + P P P P G
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 3571
Query: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
+Q P + P P P ++PTT + T TPT P G
Sbjct: 3572 TQ-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 3617
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/294 (21%), Positives = 89/294 (30%), Gaps = 34/294 (11%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3578
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV- 248
PI T P P G P+ P P P PT P+ + ++
Sbjct: 3579 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3638
Query: 249 ----KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
P P+ P P P G P + P P P P
Sbjct: 3639 TGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3696
Query: 301 SCSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
+ + P P P +++ TP P P + + P P P P G
Sbjct: 3697 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 3755
Query: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
+Q P + P P P ++PTT + T TPT P G
Sbjct: 3756 TQ-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 3801
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/294 (21%), Positives = 89/294 (30%), Gaps = 34/294 (11%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 3703 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3762
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV- 248
PI T P P G P+ P P P PT P+ + ++
Sbjct: 3763 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3822
Query: 249 ----KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
P P+ P P P G P + P P P P
Sbjct: 3823 TGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3880
Query: 301 SCSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
+ + P P P +++ TP P P + + P P P P G
Sbjct: 3881 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 3939
Query: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
+Q P + P P P ++PTT + T TPT P G
Sbjct: 3940 TQ-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 3985
Score = 49.7 bits (117), Expect = 6e-06
Identities = 64/294 (21%), Positives = 89/294 (30%), Gaps = 34/294 (11%)
Query: 136 PNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV-PAPPPPTPPPPPPPLPPPLPSSS 194
P T +G P +P T+ T P P T P P P P+++
Sbjct: 3887 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3946
Query: 195 PIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP-----PTPPPLPPASVLSDKAV- 248
PI T P P G P+ P P P PT P+ + ++
Sbjct: 3947 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4006
Query: 249 ----KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYA 300
P P+ P P P G P + P P P P
Sbjct: 4007 TGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4064
Query: 301 SCSPRASLPAP-------PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
+ + P P P +++ TP P P + + P P P P G
Sbjct: 4065 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTG 4123
Query: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPP-ARSPTTELSSKSQQATAWTPTQQPGG 406
+Q P + P P P ++PTT + T TPT P G
Sbjct: 4124 TQ-----TPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 4169
Score = 48.1 bits (113), Expect = 2e-05
Identities = 75/355 (21%), Positives = 107/355 (30%), Gaps = 78/355 (21%)
Query: 13 PPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQ 72
P P P G P + P++T T+ P G T + T + P
Sbjct: 4117 PTPTPTGTQTP---TTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTPT 4168
Query: 73 IESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPS 132
G + T +T T+ P P G T GP + +
Sbjct: 4169 ----------GTQTPTTTPITTTTTVT-------PTPTPTG--------TQTGPPTHTST 4203
Query: 133 PRLPNKTISGPLIPPASPRLGNTS-----EAHGAARTAPPRPNVPAPPPPTPPPPPPPLP 187
+ T S P ++P+ ++ E+ T PP + + PP+ P P
Sbjct: 4204 APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTS 4263
Query: 188 PPLPSSSPIKTPLVSPPGPLTKGNLP--VVAPPVPCAPPPPPPPPPPTPPPLPPASVLSD 245
S P T SPPG T+G AP PTP PL S++
Sbjct: 4264 GGHTLSPPPSTT-TSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRT 4322
Query: 246 KAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQ------------------ 287
++P P +L C P +
Sbjct: 4323 TGLRPY-----------PSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEF 4371
Query: 288 ---EPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQK 339
P+ P P P +P S P P P S TP PP+ P F P Q+
Sbjct: 4372 YNWSCPSTPSPTP-----TPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQE 4421
Score = 34.3 bits (77), Expect = 0.26
Identities = 64/275 (23%), Positives = 84/275 (30%), Gaps = 55/275 (20%)
Query: 2 PVPPPPPPPLPPPPPPLGAP--------PPPPPSAPPVSTDTSSLRRADPKGRSALLADI 53
P P P PP AP PPP S P S TSS + LL+ +
Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES----TTLLSTL 4241
Query: 54 QQGTRLRKVTQINDRSAPQIES---------SKGTNKEG----GGSANTRGASTPPTLGD 100
+ + +AP S S T+ G G + + A TP T+
Sbjct: 4242 PPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQT 4301
Query: 101 LFAGGF-PVLRPAGQRDVAGGKTGQGPGSR-------------APSPRLPNKTISGPLIP 146
+ P P + TG P AP + N T G
Sbjct: 4302 TTTSAWTPTPTPLSTPSIIR-TTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTY-GDTCY 4359
Query: 147 PASPRLGNTSEAHGAARTAPPRPN-VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPG 205
+ L T E + + + P P P+ PTP P P P + P + P PP
Sbjct: 4360 FVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPR 4419
Query: 206 -------------PLTKGNLPVVAPPVPCAPPPPP 227
K N V V C PPP P
Sbjct: 4420 QENETWWLCDCFMATCKYNNTVEIVKVECEPPPMP 4454
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 105 bits (261), Expect = 1e-22
Identities = 91/271 (33%), Positives = 104/271 (38%), Gaps = 63/271 (23%)
Query: 112 AGQRDVAGGKTGQGPGSRAPSP-------RLPNKTISGPLIP-PASPRLGNTSEAHGAAR 163
+GQ G G SRA P R P G P PA P G A +
Sbjct: 177 SGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGP--GGPPPPFPAGQ 234
Query: 164 TAPPRPNVPAPPPPTPPPPPPP---LPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVP 220
T PPRP + P PP PP PPPP LPPPL PP + PV+ P P
Sbjct: 235 T-PPRPPLGPPGPPGPPGPPPPGQVLPPPL----------AGPPNRGDRPPPPVLFPGQP 283
Query: 221 CAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPA 280
PP P PP PPP+P PP PPP PP P
Sbjct: 284 FGQPPLGPLPPGPPPPVPGYGP---------------PPGPPPPQQGPP--------PPP 320
Query: 281 SPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKA 340
P PP PP PL P + +P LP PP PG PPP P +P+F PP +
Sbjct: 321 GPF-----PPRPPGPLGPPLTLAPPPHLPGPP-PG------APPPAPHVNPAFFPPPTNS 368
Query: 341 GAQAL----PAPPAPPGSQPFLQKKRHGRPG 367
G P P P G P + +G PG
Sbjct: 369 GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399
Score = 81.3 bits (199), Expect = 2e-15
Identities = 78/249 (31%), Positives = 83/249 (33%), Gaps = 51/249 (20%)
Query: 141 SGPLIPPASPRLGNTSEAHGAAR---TAPPRPNVPAPPPPTPPPPPPPL--PPPLPSSSP 195
+GP P S R G R P P P P PPPP P PP P P
Sbjct: 186 AGP--PGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGP 243
Query: 196 IKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPL 255
P PPGP PP PPP PP P PP +P L PL
Sbjct: 244 PGPP--GPPGP---------PPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292
Query: 256 HLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPG 315
PP PPP P GY G P P Q PP P PP PP P P P LPG
Sbjct: 293 --PPGPPP----PVPGY-GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345
Query: 316 VNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNP 375
PPP P PPAP + F + + P
Sbjct: 346 -------PPPGAP-------------------PPAPHVNPAFFPPPTNSGMPTSDSRGPP 379
Query: 376 PPAPPARSP 384
P P R P
Sbjct: 380 PTDPYGRPP 388
Score = 70.1 bits (170), Expect = 4e-12
Identities = 70/214 (32%), Positives = 77/214 (35%), Gaps = 34/214 (15%)
Query: 203 PPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPP 262
P G +G P P P P P PP PP P + P P P PP
Sbjct: 198 PQGGRGRGRFPGAVPGGDRFPGPAGPGGPP--PPFPAGQTPPRPPLGPP-GPPGPPGPPP 254
Query: 263 PLPLLPP--CGYPGLKAEPASPAQDAQEPPAPPP--PLPPYASCSPRASLPAPPLPGVNS 318
P +LPP G P P P +P PP PLPP P PP+PG
Sbjct: 255 PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---------PPPPVPGYG- 304
Query: 319 SSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG--SQPFLQKKRHGRPGAGGGKLNPP 376
PPP PP P Q PP G P PP PPG P PG G PP
Sbjct: 305 ----PPPGPP--PPQQGPPPPPG----PFPPRPPGPLGPPLTLAPPPHLPGPPPGA--PP 352
Query: 377 PAP---PARSPTTELSSKSQQATAWTPTQQPGGQ 407
PAP PA P S + P P G+
Sbjct: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386
Score = 70.1 bits (170), Expect = 4e-12
Identities = 74/261 (28%), Positives = 81/261 (31%), Gaps = 100/261 (38%)
Query: 4 PPPPPPPLP----PPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRL 59
P PPPP P PP PPLG P PP P PP A P R
Sbjct: 223 PGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNR------------- 269
Query: 60 RKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG 119
DR P + LF G +P GQ +
Sbjct: 270 ------GDRPPPPV---------------------------LFPG-----QPFGQPPL-- 289
Query: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
GP P P +P GP PP P PP+ P PP P P
Sbjct: 290 -----GPLPPGPPPPVPG---YGP--PPGPP---------------PPQQGPPPPPGPFP 324
Query: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPP-TPPPLP 238
P PP PL PPL + P P + P P APPP P P PPP
Sbjct: 325 PRPPGPLGPPLTLAPP-----------------PHLPGPPPGAPPPAPHVNPAFFPPPTN 367
Query: 239 PASVLSDKAVKPQLAPLHLPP 259
SD P P PP
Sbjct: 368 SGMPTSDSRGPPPTDPYGRPP 388
Score = 47.4 bits (111), Expect = 3e-05
Identities = 58/212 (27%), Positives = 65/212 (30%), Gaps = 77/212 (36%)
Query: 2 PVPP--PPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSS---LRRADPKGRSALLADIQQG 56
P PP PP PP PP PPP G PPP + PP D L P G+ L
Sbjct: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPL------- 289
Query: 57 TRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRD 116
+ P + G G +G PP G FP
Sbjct: 290 ------GPLPPGPPPPV---PGYGPPPGPPPPQQGPPPPP-------GPFP--------- 324
Query: 117 VAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPP 176
PR P GPL PP T P P++P PPP
Sbjct: 325 ----------------PRPP-----GPLGPPL---------------TLAPPPHLPGPPP 348
Query: 177 PTPPPPPPP----LPPPLPSSSPIKTPLVSPP 204
PPP P PPP S P PP
Sbjct: 349 GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP 380
Score = 36.6 bits (83), Expect = 0.052
Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 16/59 (27%)
Query: 2 PVPPP----PPPPLPPPPPPLGAPP----------PPPPSAPPVSTDTSSLRRADPKGR 46
P+ PP PPP LP PPP GAPP PPP ++ ++D+ DP GR
Sbjct: 330 PLGPPLTLAPPPHLPGPPP--GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 103 bits (258), Expect = 3e-22
Identities = 127/455 (27%), Positives = 173/455 (38%), Gaps = 66/455 (14%)
Query: 1 MPVPP---PPPPPLP---PPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQ 54
+P PP PP PPL PPPPP+ AP PP P++P T R P G + +D+
Sbjct: 208 IPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP----HTVGTRLFPPGGVTKWKSDVA 263
Query: 55 QGTRLRKVTQINDRSAPQIE--SSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA 112
R + T+ + +P S+ G N E + PPT + PV
Sbjct: 264 LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT--PVRTSSIPVQEAQ 321
Query: 113 GQRDVAGGKTGQGPGSRAPSP--------------RLPNKTISGPL--IPPASPRLGNT- 155
G T + P SR P P R P G L PASPRLG +
Sbjct: 322 EAPRKEEGATKKAP-SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQ 380
Query: 156 SEAHGAARTAPPRPNVPAPPPPTPPPPP--PPLPPPLPSSSPIKTPLVSPPGPLTKGNLP 213
S+A A T PP P +P P PP PPP P PP PPLP + PP TK
Sbjct: 381 SQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQ----KAAHPPAGFTK-TPK 435
Query: 214 VVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP-------IPPPLPL 266
+P + P PP P + P+ + ++ +LA P P
Sbjct: 436 SSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPT 495
Query: 267 LPPCGYPGLKAEPASPAQDA-------QEPPAPPPPLPPYASCSPRASLPAPPLPGVNSS 319
+ P G K P P ++ PP P +S + + P+ LP V+
Sbjct: 496 VAPQSKEGKKG-PRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYI 554
Query: 320 SETPPPLPPKSPSFQAPPQKAGAQALPAPPA----PPGSQPFLQKKRHGRPGAGGGKLNP 375
+ P + + + + A A P+ PP +P L+ R GA KL+
Sbjct: 555 PQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPP--KPRLEGGRICENGADDDKLSK 612
Query: 376 PPA---PPARS---PTTELSSKSQQATAWTPTQQP 404
P A PP + PTT L K+ A P P
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATP 647
Score = 96.7 bits (239), Expect = 4e-20
Identities = 105/334 (31%), Positives = 126/334 (37%), Gaps = 102/334 (30%)
Query: 144 LIPPASPRLGNTSEAHGAART-APPRPNVPAPPPPTPPPPPPPL---PPPLPSSSPIKTP 199
LIPP P A G + + P P P PP+ PPPPPL PPP PS +P P
Sbjct: 138 LIPPPPP-----GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPP 192
Query: 200 LV---SPPGPLTKGNLPV---VAPPVP----CAPPPPPPPPPPTPPPLPPASV------- 242
++ SPP L+ ++P PP P APPPPP P P P P P +V
Sbjct: 193 VLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP 252
Query: 243 ------LSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEP----------------- 279
SD A+ + A PP P P G EP
Sbjct: 253 GGVTKWKSDVALNGRQAEA-TRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVR 311
Query: 280 --ASPAQDAQEPP---------APPP-PLPPYASCSP------------------RASLP 309
+ P Q+AQE P AP PLPP P +A+ P
Sbjct: 312 TSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP 371
Query: 310 APPLPGVNSS-----SETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHG 364
A P G + S + TPPP PP P APP PAPP PP + P ++
Sbjct: 372 ASPRLGQSQSQADERAGTPPPAPPLPP--PAPPLPP-----PAPPLPPAAPPLPCAQKAA 424
Query: 365 RPGAGGGK--------LNPPPAPPARSPTTELSS 390
P AG K L P P PP SP SS
Sbjct: 425 HPPAGFTKTPKSSSPALKPKPNPP--SPENTASS 456
Score = 75.9 bits (185), Expect = 8e-14
Identities = 111/414 (26%), Positives = 137/414 (33%), Gaps = 89/414 (21%)
Query: 3 VPPPPPPPLPPPP-----PPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
+PPPPP P P PP PP G+P P PPS P L P + +
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAP-PPPPLLLEPPPPPSMAPPPPPV---- 193
Query: 58 RLRKVTQINDRSAPQIESSKGTNKEGGGSANTR------GASTPPTLGDLFAGGFPVLRP 111
L ++ + S+P I + A A PP G + P
Sbjct: 194 -LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP 252
Query: 112 AG----QRDVA-GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAP 166
G + DVA G+ Q +RA PR P + L P P L + + P
Sbjct: 253 GGVTKWKSDVALNGR--QAEATRASPPRSPAEPKGSALGPNPEPHL----TFPRSFKVPP 306
Query: 167 PRP----NVPAPPPPTPP----------PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNL 212
P P ++P P P PLPP + P P G L
Sbjct: 307 PTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGEL 366
Query: 213 PVVAPPVP------------CAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPI 260
AP P PPP PP PP PPLPP AP LPP
Sbjct: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP------------AP-PLPPA 413
Query: 261 PPPLPLL-----PPCGY--------PGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRAS 307
PPLP PP G+ P LK +P P+ + AP P R
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNE 473
Query: 308 LPAPPLPGVN------SSSETPPPLPPKSPSFQAP--PQKAGAQALPAPPAPPG 353
L A L G S P P + P P+K +LPA PPG
Sbjct: 474 L-AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG 526
Score = 74.3 bits (181), Expect = 2e-13
Identities = 79/297 (26%), Positives = 97/297 (32%), Gaps = 92/297 (30%)
Query: 179 PPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLP 238
PPPPP P P P S PPG P+P P PPPPP P P
Sbjct: 140 PPPPPGPAPGPPQDIS-------EPPG----------GSPLPSPPSTAPPPPPLLLEPPP 182
Query: 239 PASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPP----- 293
P S+ PPP P+L P + P+ P PPAPP
Sbjct: 183 PPSMA-----------------PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLA 225
Query: 294 PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSF------QAPPQKAGAQALPA 347
PP PP + +P PAP P + PP K S QA +A PA
Sbjct: 226 PPPPPVPAPAP----PAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPA 281
Query: 348 PPAP----PGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP-----TTELSSKSQQATAW 398
P P +P L R + PPP P S E K + AT
Sbjct: 282 EPKGSALGPNPEPHLTFPRSFKV--------PPPTPVRTSSIPVQEAQEAPRKEEGATKK 333
Query: 399 TPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPG 455
P++ P PP +P ++YP + P PG
Sbjct: 334 APSRLP--------------------------LPPSFHIRPASQVYPDRAPEPDCPG 364
Score = 68.6 bits (166), Expect = 1e-11
Identities = 112/440 (25%), Positives = 144/440 (32%), Gaps = 74/440 (16%)
Query: 5 PPPPPPLPPPPPPLGAPPPP-PPSAPPVSTDTSSLR-----RADPKGRSALLADIQQGTR 58
PPP PPLPPP PPL P PP PP+APP+ + PK S L
Sbjct: 390 PPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKP------ 443
Query: 59 LRKVTQINDRSAPQIESSKGTN-KEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117
+ N S SS + ++ R G F RP G
Sbjct: 444 -----KPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRP-GPTVA 497
Query: 118 AGGKTGQGPGSRAPSPRLPNK----TISGPLIPPASPR--LGNTSEAHGAARTAPPRPNV 171
K G+ PRLP K ++ PP P LG +S A + P+V
Sbjct: 498 PQSKEGK------KGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSV 551
Query: 172 PAPPPPTPPPPPPPLPPPLP---SSSPIKTPLVS----PPGP-LTKGNLPVVAPPVPCAP 223
P +P P + L SS+ K S PP P L G +
Sbjct: 552 DYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLS 611
Query: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA 283
P PP L P + L KA+ P +PP P EPA P
Sbjct: 612 KPVAKNLPPQSTTLLPTTSLQPKAMLG--------------PAIPPKATP----EPAIPP 653
Query: 284 QDAQEPPAPP-----PPLPPYASCSPRASLPAPPLPGVNSSSETPPP-----LPPKSPSF 333
+ P PP P P A+ P L A P + S++ T P + K
Sbjct: 654 KATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGP 713
Query: 334 QAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPA-------RSPTT 386
P+K +Q + P G + R GA PP P P
Sbjct: 714 AGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHC 773
Query: 387 ELSSKSQQATAWTPTQQPGG 406
SS S++ PT GG
Sbjct: 774 HQSSLSREVAVVMPTLARGG 793
Score = 59.7 bits (143), Expect = 6e-09
Identities = 122/507 (24%), Positives = 158/507 (31%), Gaps = 119/507 (23%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSA--------------------------PPVSTDT 35
P PPP PPLPPP PPL PP P A PP +T
Sbjct: 394 PPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT 453
Query: 36 SSLRRADPKGRSAL------LADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANT 89
+S D + S + LA G+R R+ ++ R P + K+G
Sbjct: 454 ASSAPVDWRDPSQMEKLRNELAAYLCGSR-REDRFLSHRPGPTVAPQSKEGKKGPRLPEK 512
Query: 90 R------GASTPPTLGDLFAGGF-------------------------PVLRP------A 112
TPP + + GG P +R A
Sbjct: 513 ETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEA 572
Query: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTI----------SGPL---IPPASPRLGNTSEAH 159
A + GS P PRL I S P+ +PP S L T+
Sbjct: 573 RLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQ 632
Query: 160 GAARTAPPRPNVPAPPPPTPP--------PPPPPLPP--PLPSSSPIKTPLVSPPGPL-- 207
A P P P P PP PP L P PL ++S TPL + GP
Sbjct: 633 PKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIA 692
Query: 208 -TKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPL 266
T LP + P P P S + P A P
Sbjct: 693 STATTLPTTTSQLMAEKDSGPAGQPEKPA--------SQEVSTPSQA--RGEGSPSEATR 742
Query: 267 LPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPL-------PGVNSS 319
LP G A P + E P P +S S ++ P L PG
Sbjct: 743 LPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVE 802
Query: 320 SETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFL-----QKKRHGRP-GAGGGKL 373
+ PP LP K P+ P + + GS L Q+ + GR GA G+
Sbjct: 803 VKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRS 862
Query: 374 NPPPAPPARSPTTELSSKSQQATAWTP 400
+ P + S E SS S + TP
Sbjct: 863 SLPGSLRDHSHQAEASSDSIFHSQGTP 889
Score = 43.1 bits (100), Expect = 6e-04
Identities = 68/270 (25%), Positives = 90/270 (33%), Gaps = 39/270 (14%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
PV PP LP PP A P PV+ + + R P + LLA Q+ + R
Sbjct: 800 PVEVKEPPGLPAKPPA-SAQPTDELLRHPVTGEV--VERGSPM--ALLLAARQRAQKGRS 854
Query: 62 VTQINDRSA-PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG 120
V RS+ P E + TP + + P L ++D
Sbjct: 855 VGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV-----PKLPKEAEKD---- 905
Query: 121 KTGQGPGSRAP-SPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
+P + +PNK PRLG +E +R R N P P P
Sbjct: 906 ---------SPLTTEIPNKW---------GPRLGRDAEGTELSR----RHNWTKPEPQAP 943
Query: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239
P LP P+ SPP P K PPPP P PP P
Sbjct: 944 VAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDP-EPPAPA 1002
Query: 240 ASVLSDKAVKPQLAPLHLPPIPPPLPLLPP 269
L ++ P+ L +P P PP
Sbjct: 1003 LQYLGRQSSPPRNNYSDLRQLPNAGPGAPP 1032
Score = 29.6 bits (65), Expect = 6.4
Identities = 32/115 (27%), Positives = 41/115 (35%), Gaps = 17/115 (14%)
Query: 276 KAEPASPAQDAQEPPAPPP---PLPPYASCSPRASLPA------------PPLPGVNSSS 320
K EP +P + P+ P PLP S P S PP P ++
Sbjct: 937 KPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDP 996
Query: 321 ETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRH--GRPGAGGGKL 373
E P P +PP+ + P A PG+ P L R G AG G L
Sbjct: 997 EPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGL 1051
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 103 bits (258), Expect = 3e-22
Identities = 127/455 (27%), Positives = 173/455 (38%), Gaps = 66/455 (14%)
Query: 1 MPVPP---PPPPPLP---PPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQ 54
+P PP PP PPL PPPPP+ AP PP P++P T R P G + +D+
Sbjct: 208 IPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP----HTVGTRLFPPGGVTKWKSDVA 263
Query: 55 QGTRLRKVTQINDRSAPQIE--SSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA 112
R + T+ + +P S+ G N E + PPT + PV
Sbjct: 264 LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT--PVRTSSIPVQEAQ 321
Query: 113 GQRDVAGGKTGQGPGSRAPSP--------------RLPNKTISGPL--IPPASPRLGNT- 155
G T + P SR P P R P G L PASPRLG +
Sbjct: 322 EAPRKEEGATKKAP-SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQ 380
Query: 156 SEAHGAARTAPPRPNVPAPPPPTPPPPP--PPLPPPLPSSSPIKTPLVSPPGPLTKGNLP 213
S+A A T PP P +P P PP PPP P PP PPLP + PP TK
Sbjct: 381 SQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQ----KAAHPPAGFTK-TPK 435
Query: 214 VVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP-------IPPPLPL 266
+P + P PP P + P+ + ++ +LA P P
Sbjct: 436 SSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPT 495
Query: 267 LPPCGYPGLKAEPASPAQDA-------QEPPAPPPPLPPYASCSPRASLPAPPLPGVNSS 319
+ P G K P P ++ PP P +S + + P+ LP V+
Sbjct: 496 VAPQSKEGKKG-PRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYI 554
Query: 320 SETPPPLPPKSPSFQAPPQKAGAQALPAPPA----PPGSQPFLQKKRHGRPGAGGGKLNP 375
+ P + + + + A A P+ PP +P L+ R GA KL+
Sbjct: 555 PQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPP--KPRLEGGRICENGADDDKLSK 612
Query: 376 PPA---PPARS---PTTELSSKSQQATAWTPTQQP 404
P A PP + PTT L K+ A P P
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATP 647
Score = 96.7 bits (239), Expect = 4e-20
Identities = 105/334 (31%), Positives = 126/334 (37%), Gaps = 102/334 (30%)
Query: 144 LIPPASPRLGNTSEAHGAART-APPRPNVPAPPPPTPPPPPPPL---PPPLPSSSPIKTP 199
LIPP P A G + + P P P PP+ PPPPPL PPP PS +P P
Sbjct: 138 LIPPPPP-----GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPP 192
Query: 200 LV---SPPGPLTKGNLPV---VAPPVP----CAPPPPPPPPPPTPPPLPPASV------- 242
++ SPP L+ ++P PP P APPPPP P P P P P +V
Sbjct: 193 VLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP 252
Query: 243 ------LSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEP----------------- 279
SD A+ + A PP P P G EP
Sbjct: 253 GGVTKWKSDVALNGRQAEA-TRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVR 311
Query: 280 --ASPAQDAQEPP---------APPP-PLPPYASCSP------------------RASLP 309
+ P Q+AQE P AP PLPP P +A+ P
Sbjct: 312 TSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP 371
Query: 310 APPLPGVNSS-----SETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHG 364
A P G + S + TPPP PP P APP PAPP PP + P ++
Sbjct: 372 ASPRLGQSQSQADERAGTPPPAPPLPP--PAPPLPP-----PAPPLPPAAPPLPCAQKAA 424
Query: 365 RPGAGGGK--------LNPPPAPPARSPTTELSS 390
P AG K L P P PP SP SS
Sbjct: 425 HPPAGFTKTPKSSSPALKPKPNPP--SPENTASS 456
Score = 75.9 bits (185), Expect = 8e-14
Identities = 111/414 (26%), Positives = 137/414 (33%), Gaps = 89/414 (21%)
Query: 3 VPPPPPPPLPPPP-----PPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
+PPPPP P P PP PP G+P P PPS P L P + +
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAP-PPPPLLLEPPPPPSMAPPPPPV---- 193
Query: 58 RLRKVTQINDRSAPQIESSKGTNKEGGGSANTR------GASTPPTLGDLFAGGFPVLRP 111
L ++ + S+P I + A A PP G + P
Sbjct: 194 -LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP 252
Query: 112 AG----QRDVA-GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAP 166
G + DVA G+ Q +RA PR P + L P P L + + P
Sbjct: 253 GGVTKWKSDVALNGR--QAEATRASPPRSPAEPKGSALGPNPEPHL----TFPRSFKVPP 306
Query: 167 PRP----NVPAPPPPTPP----------PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNL 212
P P ++P P P PLPP + P P G L
Sbjct: 307 PTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGEL 366
Query: 213 PVVAPPVP------------CAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPI 260
AP P PPP PP PP PPLPP AP LPP
Sbjct: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP------------AP-PLPPA 413
Query: 261 PPPLPLL-----PPCGY--------PGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRAS 307
PPLP PP G+ P LK +P P+ + AP P R
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNE 473
Query: 308 LPAPPLPGVN------SSSETPPPLPPKSPSFQAP--PQKAGAQALPAPPAPPG 353
L A L G S P P + P P+K +LPA PPG
Sbjct: 474 L-AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG 526
Score = 74.3 bits (181), Expect = 2e-13
Identities = 79/297 (26%), Positives = 97/297 (32%), Gaps = 92/297 (30%)
Query: 179 PPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLP 238
PPPPP P P P S PPG P+P P PPPPP P P
Sbjct: 140 PPPPPGPAPGPPQDIS-------EPPG----------GSPLPSPPSTAPPPPPLLLEPPP 182
Query: 239 PASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPP----- 293
P S+ PPP P+L P + P+ P PPAPP
Sbjct: 183 PPSMA-----------------PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLA 225
Query: 294 PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSF------QAPPQKAGAQALPA 347
PP PP + +P PAP P + PP K S QA +A PA
Sbjct: 226 PPPPPVPAPAP----PAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPA 281
Query: 348 PPAP----PGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP-----TTELSSKSQQATAW 398
P P +P L R + PPP P S E K + AT
Sbjct: 282 EPKGSALGPNPEPHLTFPRSFKV--------PPPTPVRTSSIPVQEAQEAPRKEEGATKK 333
Query: 399 TPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPG 455
P++ P PP +P ++YP + P PG
Sbjct: 334 APSRLP--------------------------LPPSFHIRPASQVYPDRAPEPDCPG 364
Score = 68.6 bits (166), Expect = 1e-11
Identities = 112/440 (25%), Positives = 144/440 (32%), Gaps = 74/440 (16%)
Query: 5 PPPPPPLPPPPPPLGAPPPP-PPSAPPVSTDTSSLR-----RADPKGRSALLADIQQGTR 58
PPP PPLPPP PPL P PP PP+APP+ + PK S L
Sbjct: 390 PPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKP------ 443
Query: 59 LRKVTQINDRSAPQIESSKGTN-KEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117
+ N S SS + ++ R G F RP G
Sbjct: 444 -----KPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRP-GPTVA 497
Query: 118 AGGKTGQGPGSRAPSPRLPNK----TISGPLIPPASPR--LGNTSEAHGAARTAPPRPNV 171
K G+ PRLP K ++ PP P LG +S A + P+V
Sbjct: 498 PQSKEGK------KGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSV 551
Query: 172 PAPPPPTPPPPPPPLPPPLP---SSSPIKTPLVS----PPGP-LTKGNLPVVAPPVPCAP 223
P +P P + L SS+ K S PP P L G +
Sbjct: 552 DYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLS 611
Query: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA 283
P PP L P + L KA+ P +PP P EPA P
Sbjct: 612 KPVAKNLPPQSTTLLPTTSLQPKAMLG--------------PAIPPKATP----EPAIPP 653
Query: 284 QDAQEPPAPP-----PPLPPYASCSPRASLPAPPLPGVNSSSETPPP-----LPPKSPSF 333
+ P PP P P A+ P L A P + S++ T P + K
Sbjct: 654 KATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGP 713
Query: 334 QAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPA-------RSPTT 386
P+K +Q + P G + R GA PP P P
Sbjct: 714 AGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHC 773
Query: 387 ELSSKSQQATAWTPTQQPGG 406
SS S++ PT GG
Sbjct: 774 HQSSLSREVAVVMPTLARGG 793
Score = 59.7 bits (143), Expect = 6e-09
Identities = 122/507 (24%), Positives = 158/507 (31%), Gaps = 119/507 (23%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSA--------------------------PPVSTDT 35
P PPP PPLPPP PPL PP P A PP +T
Sbjct: 394 PPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT 453
Query: 36 SSLRRADPKGRSAL------LADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANT 89
+S D + S + LA G+R R+ ++ R P + K+G
Sbjct: 454 ASSAPVDWRDPSQMEKLRNELAAYLCGSR-REDRFLSHRPGPTVAPQSKEGKKGPRLPEK 512
Query: 90 R------GASTPPTLGDLFAGGF-------------------------PVLRP------A 112
TPP + + GG P +R A
Sbjct: 513 ETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEA 572
Query: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTI----------SGPL---IPPASPRLGNTSEAH 159
A + GS P PRL I S P+ +PP S L T+
Sbjct: 573 RLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQ 632
Query: 160 GAARTAPPRPNVPAPPPPTPP--------PPPPPLPP--PLPSSSPIKTPLVSPPGPL-- 207
A P P P P PP PP L P PL ++S TPL + GP
Sbjct: 633 PKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIA 692
Query: 208 -TKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPL 266
T LP + P P P S + P A P
Sbjct: 693 STATTLPTTTSQLMAEKDSGPAGQPEKPA--------SQEVSTPSQA--RGEGSPSEATR 742
Query: 267 LPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPL-------PGVNSS 319
LP G A P + E P P +S S ++ P L PG
Sbjct: 743 LPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVE 802
Query: 320 SETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFL-----QKKRHGRP-GAGGGKL 373
+ PP LP K P+ P + + GS L Q+ + GR GA G+
Sbjct: 803 VKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRS 862
Query: 374 NPPPAPPARSPTTELSSKSQQATAWTP 400
+ P + S E SS S + TP
Sbjct: 863 SLPGSLRDHSHQAEASSDSIFHSQGTP 889
Score = 43.1 bits (100), Expect = 6e-04
Identities = 68/270 (25%), Positives = 90/270 (33%), Gaps = 39/270 (14%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
PV PP LP PP A P PV+ + + R P + LLA Q+ + R
Sbjct: 800 PVEVKEPPGLPAKPPA-SAQPTDELLRHPVTGEV--VERGSPM--ALLLAARQRAQKGRS 854
Query: 62 VTQINDRSA-PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG 120
V RS+ P E + TP + + P L ++D
Sbjct: 855 VGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV-----PKLPKEAEKD---- 905
Query: 121 KTGQGPGSRAP-SPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
+P + +PNK PRLG +E +R R N P P P
Sbjct: 906 ---------SPLTTEIPNKW---------GPRLGRDAEGTELSR----RHNWTKPEPQAP 943
Query: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239
P LP P+ SPP P K PPPP P PP P
Sbjct: 944 VAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDP-EPPAPA 1002
Query: 240 ASVLSDKAVKPQLAPLHLPPIPPPLPLLPP 269
L ++ P+ L +P P PP
Sbjct: 1003 LQYLGRQSSPPRNNYSDLRQLPNAGPGAPP 1032
Score = 29.6 bits (65), Expect = 6.4
Identities = 32/115 (27%), Positives = 41/115 (35%), Gaps = 17/115 (14%)
Query: 276 KAEPASPAQDAQEPPAPPP---PLPPYASCSPRASLPA------------PPLPGVNSSS 320
K EP +P + P+ P PLP S P S PP P ++
Sbjct: 937 KPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDP 996
Query: 321 ETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRH--GRPGAGGGKL 373
E P P +PP+ + P A PG+ P L R G AG G L
Sbjct: 997 EPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGL 1051
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 103 bits (258), Expect = 3e-22
Identities = 127/455 (27%), Positives = 173/455 (38%), Gaps = 66/455 (14%)
Query: 1 MPVPP---PPPPPLP---PPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQ 54
+P PP PP PPL PPPPP+ AP PP P++P T R P G + +D+
Sbjct: 208 IPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP----HTVGTRLFPPGGVTKWKSDVA 263
Query: 55 QGTRLRKVTQINDRSAPQIE--SSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA 112
R + T+ + +P S+ G N E + PPT + PV
Sbjct: 264 LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT--PVRTSSIPVQEAQ 321
Query: 113 GQRDVAGGKTGQGPGSRAPSP--------------RLPNKTISGPL--IPPASPRLGNT- 155
G T + P SR P P R P G L PASPRLG +
Sbjct: 322 EAPRKEEGATKKAP-SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQ 380
Query: 156 SEAHGAARTAPPRPNVPAPPPPTPPPPP--PPLPPPLPSSSPIKTPLVSPPGPLTKGNLP 213
S+A A T PP P +P P PP PPP P PP PPLP + PP TK
Sbjct: 381 SQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQ----KAAHPPAGFTK-TPK 435
Query: 214 VVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP-------IPPPLPL 266
+P + P PP P + P+ + ++ +LA P P
Sbjct: 436 SSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPT 495
Query: 267 LPPCGYPGLKAEPASPAQDA-------QEPPAPPPPLPPYASCSPRASLPAPPLPGVNSS 319
+ P G K P P ++ PP P +S + + P+ LP V+
Sbjct: 496 VAPQSKEGKKG-PRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYI 554
Query: 320 SETPPPLPPKSPSFQAPPQKAGAQALPAPPA----PPGSQPFLQKKRHGRPGAGGGKLNP 375
+ P + + + + A A P+ PP +P L+ R GA KL+
Sbjct: 555 PQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPP--KPRLEGGRICENGADDDKLSK 612
Query: 376 PPA---PPARS---PTTELSSKSQQATAWTPTQQP 404
P A PP + PTT L K+ A P P
Sbjct: 613 PVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATP 647
Score = 96.7 bits (239), Expect = 4e-20
Identities = 105/334 (31%), Positives = 126/334 (37%), Gaps = 102/334 (30%)
Query: 144 LIPPASPRLGNTSEAHGAART-APPRPNVPAPPPPTPPPPPPPL---PPPLPSSSPIKTP 199
LIPP P A G + + P P P PP+ PPPPPL PPP PS +P P
Sbjct: 138 LIPPPPP-----GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPP 192
Query: 200 LV---SPPGPLTKGNLPV---VAPPVP----CAPPPPPPPPPPTPPPLPPASV------- 242
++ SPP L+ ++P PP P APPPPP P P P P P +V
Sbjct: 193 VLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP 252
Query: 243 ------LSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEP----------------- 279
SD A+ + A PP P P G EP
Sbjct: 253 GGVTKWKSDVALNGRQAEA-TRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVR 311
Query: 280 --ASPAQDAQEPP---------APPP-PLPPYASCSP------------------RASLP 309
+ P Q+AQE P AP PLPP P +A+ P
Sbjct: 312 TSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP 371
Query: 310 APPLPGVNSS-----SETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHG 364
A P G + S + TPPP PP P APP PAPP PP + P ++
Sbjct: 372 ASPRLGQSQSQADERAGTPPPAPPLPP--PAPPLPP-----PAPPLPPAAPPLPCAQKAA 424
Query: 365 RPGAGGGK--------LNPPPAPPARSPTTELSS 390
P AG K L P P PP SP SS
Sbjct: 425 HPPAGFTKTPKSSSPALKPKPNPP--SPENTASS 456
Score = 75.9 bits (185), Expect = 8e-14
Identities = 111/414 (26%), Positives = 137/414 (33%), Gaps = 89/414 (21%)
Query: 3 VPPPPPPPLPPPP-----PPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
+PPPPP P P PP PP G+P P PPS P L P + +
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAP-PPPPLLLEPPPPPSMAPPPPPV---- 193
Query: 58 RLRKVTQINDRSAPQIESSKGTNKEGGGSANTR------GASTPPTLGDLFAGGFPVLRP 111
L ++ + S+P I + A A PP G + P
Sbjct: 194 -LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPP 252
Query: 112 AG----QRDVA-GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAP 166
G + DVA G+ Q +RA PR P + L P P L + + P
Sbjct: 253 GGVTKWKSDVALNGR--QAEATRASPPRSPAEPKGSALGPNPEPHL----TFPRSFKVPP 306
Query: 167 PRP----NVPAPPPPTPP----------PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNL 212
P P ++P P P PLPP + P P G L
Sbjct: 307 PTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGEL 366
Query: 213 PVVAPPVP------------CAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPI 260
AP P PPP PP PP PPLPP AP LPP
Sbjct: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP------------AP-PLPPA 413
Query: 261 PPPLPLL-----PPCGY--------PGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRAS 307
PPLP PP G+ P LK +P P+ + AP P R
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNE 473
Query: 308 LPAPPLPGVN------SSSETPPPLPPKSPSFQAP--PQKAGAQALPAPPAPPG 353
L A L G S P P + P P+K +LPA PPG
Sbjct: 474 L-AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG 526
Score = 74.3 bits (181), Expect = 2e-13
Identities = 79/297 (26%), Positives = 97/297 (32%), Gaps = 92/297 (30%)
Query: 179 PPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLP 238
PPPPP P P P S PPG P+P P PPPPP P P
Sbjct: 140 PPPPPGPAPGPPQDIS-------EPPG----------GSPLPSPPSTAPPPPPLLLEPPP 182
Query: 239 PASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPP----- 293
P S+ PPP P+L P + P+ P PPAPP
Sbjct: 183 PPSMA-----------------PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLA 225
Query: 294 PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSF------QAPPQKAGAQALPA 347
PP PP + +P PAP P + PP K S QA +A PA
Sbjct: 226 PPPPPVPAPAP----PAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPA 281
Query: 348 PPAP----PGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP-----TTELSSKSQQATAW 398
P P +P L R + PPP P S E K + AT
Sbjct: 282 EPKGSALGPNPEPHLTFPRSFKV--------PPPTPVRTSSIPVQEAQEAPRKEEGATKK 333
Query: 399 TPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPG 455
P++ P PP +P ++YP + P PG
Sbjct: 334 APSRLP--------------------------LPPSFHIRPASQVYPDRAPEPDCPG 364
Score = 68.6 bits (166), Expect = 1e-11
Identities = 112/440 (25%), Positives = 144/440 (32%), Gaps = 74/440 (16%)
Query: 5 PPPPPPLPPPPPPLGAPPPP-PPSAPPVSTDTSSLR-----RADPKGRSALLADIQQGTR 58
PPP PPLPPP PPL P PP PP+APP+ + PK S L
Sbjct: 390 PPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKP------ 443
Query: 59 LRKVTQINDRSAPQIESSKGTN-KEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117
+ N S SS + ++ R G F RP G
Sbjct: 444 -----KPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRP-GPTVA 497
Query: 118 AGGKTGQGPGSRAPSPRLPNK----TISGPLIPPASPR--LGNTSEAHGAARTAPPRPNV 171
K G+ PRLP K ++ PP P LG +S A + P+V
Sbjct: 498 PQSKEGK------KGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSV 551
Query: 172 PAPPPPTPPPPPPPLPPPLP---SSSPIKTPLVS----PPGP-LTKGNLPVVAPPVPCAP 223
P +P P + L SS+ K S PP P L G +
Sbjct: 552 DYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLS 611
Query: 224 PPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA 283
P PP L P + L KA+ P +PP P EPA P
Sbjct: 612 KPVAKNLPPQSTTLLPTTSLQPKAMLG--------------PAIPPKATP----EPAIPP 653
Query: 284 QDAQEPPAPP-----PPLPPYASCSPRASLPAPPLPGVNSSSETPPP-----LPPKSPSF 333
+ P PP P P A+ P L A P + S++ T P + K
Sbjct: 654 KATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGP 713
Query: 334 QAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPA-------RSPTT 386
P+K +Q + P G + R GA PP P P
Sbjct: 714 AGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHC 773
Query: 387 ELSSKSQQATAWTPTQQPGG 406
SS S++ PT GG
Sbjct: 774 HQSSLSREVAVVMPTLARGG 793
Score = 59.7 bits (143), Expect = 6e-09
Identities = 122/507 (24%), Positives = 158/507 (31%), Gaps = 119/507 (23%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSA--------------------------PPVSTDT 35
P PPP PPLPPP PPL PP P A PP +T
Sbjct: 394 PPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT 453
Query: 36 SSLRRADPKGRSAL------LADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANT 89
+S D + S + LA G+R R+ ++ R P + K+G
Sbjct: 454 ASSAPVDWRDPSQMEKLRNELAAYLCGSR-REDRFLSHRPGPTVAPQSKEGKKGPRLPEK 512
Query: 90 R------GASTPPTLGDLFAGGF-------------------------PVLRP------A 112
TPP + + GG P +R A
Sbjct: 513 ETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEA 572
Query: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTI----------SGPL---IPPASPRLGNTSEAH 159
A + GS P PRL I S P+ +PP S L T+
Sbjct: 573 RLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQ 632
Query: 160 GAARTAPPRPNVPAPPPPTPP--------PPPPPLPP--PLPSSSPIKTPLVSPPGPL-- 207
A P P P P PP PP L P PL ++S TPL + GP
Sbjct: 633 PKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIA 692
Query: 208 -TKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPL 266
T LP + P P P S + P A P
Sbjct: 693 STATTLPTTTSQLMAEKDSGPAGQPEKPA--------SQEVSTPSQA--RGEGSPSEATR 742
Query: 267 LPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPL-------PGVNSS 319
LP G A P + E P P +S S ++ P L PG
Sbjct: 743 LPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVE 802
Query: 320 SETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFL-----QKKRHGRP-GAGGGKL 373
+ PP LP K P+ P + + GS L Q+ + GR GA G+
Sbjct: 803 VKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRS 862
Query: 374 NPPPAPPARSPTTELSSKSQQATAWTP 400
+ P + S E SS S + TP
Sbjct: 863 SLPGSLRDHSHQAEASSDSIFHSQGTP 889
Score = 43.1 bits (100), Expect = 6e-04
Identities = 68/270 (25%), Positives = 90/270 (33%), Gaps = 39/270 (14%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
PV PP LP PP A P PV+ + + R P + LLA Q+ + R
Sbjct: 800 PVEVKEPPGLPAKPPA-SAQPTDELLRHPVTGEV--VERGSPM--ALLLAARQRAQKGRS 854
Query: 62 VTQINDRSA-PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG 120
V RS+ P E + TP + + P L ++D
Sbjct: 855 VGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV-----PKLPKEAEKD---- 905
Query: 121 KTGQGPGSRAP-SPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
+P + +PNK PRLG +E +R R N P P P
Sbjct: 906 ---------SPLTTEIPNKW---------GPRLGRDAEGTELSR----RHNWTKPEPQAP 943
Query: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239
P LP P+ SPP P K PPPP P PP P
Sbjct: 944 VAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDP-EPPAPA 1002
Query: 240 ASVLSDKAVKPQLAPLHLPPIPPPLPLLPP 269
L ++ P+ L +P P PP
Sbjct: 1003 LQYLGRQSSPPRNNYSDLRQLPNAGPGAPP 1032
Score = 29.6 bits (65), Expect = 6.4
Identities = 32/115 (27%), Positives = 41/115 (35%), Gaps = 17/115 (14%)
Query: 276 KAEPASPAQDAQEPPAPPP---PLPPYASCSPRASLPA------------PPLPGVNSSS 320
K EP +P + P+ P PLP S P S PP P ++
Sbjct: 937 KPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDP 996
Query: 321 ETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRH--GRPGAGGGKL 373
E P P +PP+ + P A PG+ P L R G AG G L
Sbjct: 997 EPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGL 1051
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 103 bits (257), Expect = 3e-22
Identities = 90/300 (30%), Positives = 113/300 (37%), Gaps = 65/300 (21%)
Query: 110 RPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPR- 168
+PA Q+ A Q P +P P P + ++ P E + AA PP+
Sbjct: 309 QPAQQQQPA-----QQPKKPSPQPSSPRQVKRAVVVSP--------KEENKAAEPPPPKI 355
Query: 169 PNVPAPPPPTPPP-PPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPP-- 225
P + PP PP PPP PPL ++ PPGP+ +LP V P P P P
Sbjct: 356 PKIETTHPPLPPAHPPPDRKPPLAAA----LGEAEPPGPVDATDLPKVQIPPPAHPAPVH 411
Query: 226 PPPPPPPTPPPLPPASVLSDKAVKPQL----------------APLH--LPPI---PPPL 264
PPP P PPP PP+S ++ + P + LPP P L
Sbjct: 412 QPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHL 471
Query: 265 PLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPP 324
P P P P P + PPA PPP P Y P + PP P + P
Sbjct: 472 PYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVP 531
Query: 325 PLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
P PP P PP + P P PPG QP + PPP PP P
Sbjct: 532 PHPP--PGLGLPP-----ASYPPPAVPPGGQPPV----------------PPPIPPPGMP 568
Score = 95.5 bits (236), Expect = 9e-20
Identities = 97/353 (27%), Positives = 121/353 (34%), Gaps = 103/353 (29%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
MP P PP P P S P S++ S ++ DP QQ + +
Sbjct: 265 MPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDP----------QQPAQQQ 314
Query: 61 KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG 120
+ Q + +PQ S + +R V
Sbjct: 315 QPAQQPKKPSPQPSSPRQV----------------------------------KRAVVVS 340
Query: 121 KTGQGPGSRAPSPRLPNKTISGPLIPPASP----------RLGNTSEAHGAARTAPPRPN 170
+ + P P++P + P +PPA P LG T P+
Sbjct: 341 PKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQ 400
Query: 171 VPAPPPPTPPPPPPPL----PPPLPSS---------------------SPIKT------- 198
+P P P P PPPL PPP PSS S +KT
Sbjct: 401 IPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGA 460
Query: 199 --PLVSPPGPLTKGNLPVVAPPVPCAPPPPPPP--------PPPTP--PPLPPASVLSDK 246
P PP L P V PP P PP PPPP PPPTP PP PP +
Sbjct: 461 LPPAYGPPAHLPYH--PHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFP 518
Query: 247 AVKPQLAPLH-LPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPP 298
P+L P H +PP PPP LPP YP P Q PP PPP +PP
Sbjct: 519 PPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPG--GQPPVPPPIPPPGMPP 569
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/161 (27%), Positives = 57/161 (35%), Gaps = 27/161 (16%)
Query: 255 LHLPPIPPPLPLLPPC--GYPGLKAEPASPAQ-DAQEP-----PAPPPPLPPYASCSPRA 306
L PP P P +P P +EP+ P Q D Q+P PA P P SPR
Sbjct: 273 LQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQ 332
Query: 307 SLPAPPLPGVNSSSETPPPLPPKSPSFQA--PPQKAGAQALPAPPAPPGSQPFLQKKRHG 364
A + + PP PPK P + PP LP PP +P L
Sbjct: 333 VKRAVVVSPKEENKAAEPP-PPKIPKIETTHPP-------LPPAHPPPDRKPPL------ 378
Query: 365 RPGAGGGKLNPP-PAPPARSPTTELSSKSQQATAWTPTQQP 404
A G+ PP P P ++ + A P P
Sbjct: 379 --AAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLP 417
Score = 39.3 bits (90), Expect = 0.008
Identities = 24/47 (51%), Positives = 24/47 (51%), Gaps = 8/47 (17%)
Query: 3 VPPPPPPP--LPP---PP---PPLGAPPPPPPSAPPVSTDTSSLRRA 41
VPP PPP LPP PP PP G PP PPP PP L RA
Sbjct: 530 VPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRA 576
Score = 32.3 bits (72), Expect = 0.99
Identities = 32/127 (25%), Positives = 44/127 (34%), Gaps = 18/127 (14%)
Query: 294 PPLPPYASCSPRASLPAPPLPGVNSS--SETPPPLPPKSPSFQAPPQKAGAQALPAPPAP 351
P P+ P + P P +P V S S++ P P+ Q P Q+ P P+P
Sbjct: 266 PHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSP 325
Query: 352 PGSQP-------FLQKKRHGR------PGAGGGKLNPPPAPPARSPTTELSSKSQQATAW 398
S P + K + P + PP PPA P K A A
Sbjct: 326 QPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPP---DRKPPLAAAL 382
Query: 399 TPTQQPG 405
+ PG
Sbjct: 383 GEAEPPG 389
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 101 bits (251), Expect = 2e-21
Identities = 135/475 (28%), Positives = 165/475 (34%), Gaps = 112/475 (23%)
Query: 5 PPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQ 64
P PP P P PP P SA +++D++ D QG+ T
Sbjct: 584 PGPPEPEEPEADQHLLPPTLPTSATSLASDST--------------FDSGQGS-----TV 624
Query: 65 INDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG-KTG 123
+D + Q G+ + S S P + G + P L Q A G G
Sbjct: 625 YSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVG 684
Query: 124 QGPGSRAP---SPRLPNKTIS-GPLIPPASPRLGNTSEAHGAARTAP------------P 167
P P P+ +S P++PP S T G + AP P
Sbjct: 685 SVPAPACPPSLQQHFPDPAMSFAPVLPPPS-----TPMPTGPGQPAPPGQQPPPLAQPTP 739
Query: 168 RPNVPAPPPPTP-PPPPPPLPPPLPSSSPIKT-----PLVSPPGPLTK-GNLPVVAPPVP 220
P V AP P P P PP LPP L +S + PL P PL +P PP+P
Sbjct: 740 LPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIP 799
Query: 221 CAPP----------PP--PPPPPPTPPPLPPASVLSDKAVKPQL-APL-----HLP---- 258
PP PP P P T PP+PP S + P L APL LP
Sbjct: 800 VVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAV 859
Query: 259 --PIPPPLPLLPPC----------------GYPGLKA------------EPASPAQDAQE 288
P PP PL PC PG+ A +P PA Q
Sbjct: 860 KLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQM 919
Query: 289 PPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAP 348
P PP P + + RA+ P P LP T PP P P PPQ P P
Sbjct: 920 APTDVPPSPHHTVQNMRATPPQPALP----PQPTLPPQPVLPPQPTLPPQPV---LPPQP 972
Query: 349 PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQ 403
PP QP L + P L P PA P R + Q A A TP Q
Sbjct: 973 TRPP--QPVLPPQPMLPPQP---VLPPQPALPVRPEPLQPHLPEQAAPAATPGSQ 1022
Score = 97.1 bits (240), Expect = 3e-20
Identities = 116/401 (28%), Positives = 144/401 (35%), Gaps = 73/401 (18%)
Query: 2 PVPP---PPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58
P PP PPP P P P + AP P P P L A G A L +Q
Sbjct: 724 PAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQA 783
Query: 59 -LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117
L+ + Q+ + P T G PP L DL P + P
Sbjct: 784 PLQPLAQVPPQMPPIPVVPPITPLAGIDGL-------PPALPDLPTATVPPVPP------ 830
Query: 118 AGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLG----NTSEAHGAARTAPPR---PN 170
P +P+ LP+ ++ PL PPASP L GA P R PN
Sbjct: 831 --------PQYFSPAVILPS--LAAPL-PPASPALPLQAVKLPHPPGAPLAMPCRTIVPN 879
Query: 171 VPAPPPPTPPPPPP-------------PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAP 217
PA P PP P P P++ P P PP P P
Sbjct: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATP 939
Query: 218 PVPCAPPPPPPPPPPTPPP---LPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPG 274
P P PP P PP P PP LPP VL + +P L P+ PP P+LPP
Sbjct: 940 PQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALP 999
Query: 275 LKAEPASPAQDAQEPPAPPP--------PLPPYASCS--------PRASLPAPPLPGV-- 316
++ EP P Q PA P P P + P A++ +PPLP V
Sbjct: 1000 VRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLL 1059
Query: 317 NSSSETPPPLPPK----SPSFQAPPQKAGAQALPAPPAPPG 353
++ E P P S S Q+ P + PA P PG
Sbjct: 1060 PAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPG 1100
Score = 63.5 bits (153), Expect = 4e-10
Identities = 124/493 (25%), Positives = 167/493 (33%), Gaps = 92/493 (18%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
PV P P P PPL P S PP ++ S+ + +L
Sbjct: 1317 PVAEHPAPEAPESSPPL-----PLSSLPPEASQDSAPYK----------------DQLSS 1355
Query: 62 VTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVL----RPA-GQRD 116
Q + ++ Q+ S G + G S+PP G P PA G
Sbjct: 1356 KEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTAS 1415
Query: 117 VAGGK-TGQGPGSRAPSPRLPNKTISGPL-IPPASPRLGNTSEAHGAARTAPPRPNVPAP 174
AGG T QG S + + +T PL + P L + A AA T + AP
Sbjct: 1416 QAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTR----DASAP 1471
Query: 175 PPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPP-PPPPPPPT 233
P PPP P P P S P + P PL LP V A P PP PT
Sbjct: 1472 REPLPPPAPEPSP-----HSGTPQPALGQPAPL----LPAAVGAVSLATSQLPSPPLGPT 1522
Query: 234 PPPLPPASVLSD---------------KAVKPQLAPL----HLPPIPPPLPLLPPCGYPG 274
PP PP+++ SD K++ +L L H+P G
Sbjct: 1523 VPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRD 1582
Query: 275 LKAEPASPAQDAQEPPAPPPPLPPY--ASCSPRASLPAP--------PLPGV-----NSS 319
EP Q E LPP + S R LP P P G SS
Sbjct: 1583 FTLEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSS 1642
Query: 320 SETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKR---HGRPG--AGGGKLN 374
S T P + ++ + + P P F++ R R G AG
Sbjct: 1643 SMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAE 1702
Query: 375 PPPAP------PARSPTTELSSKSQQATAWTPTQQ----PGGQLRNGSLHIIDDFESKFT 424
PPP+ A P T L +++ + P QQ P + S+ D + +
Sbjct: 1703 PPPSDMGTVGGQASHPQT-LGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQDEWTLAS 1761
Query: 425 FHSVEDFPPPDEY 437
HS+ PPD Y
Sbjct: 1762 PHSLRYSAPPDVY 1774
Score = 48.9 bits (115), Expect = 1e-05
Identities = 88/341 (25%), Positives = 111/341 (32%), Gaps = 79/341 (23%)
Query: 3 VPPPPPP--------------PLPPPPPPL---GAPPPPPPSAP---------PVSTDTS 36
VPP PPP PLPP P L P PP AP P + T
Sbjct: 825 VPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATI 884
Query: 37 SLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPP 96
L P G +AL I + + PQ+ + N R P
Sbjct: 885 PLLAVAPPGVAAL--SIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQP 942
Query: 97 TLGDL-FAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTI--SGPLIPP--ASPR 151
L PVL P Q + +R P P LP + + P++PP A P
Sbjct: 943 ALPPQPTLPPQPVLPP--QPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPV 1000
Query: 152 LGNTSEAHGAARTAP------------PRP---NVPAPPPPTPPPPPPPLPPPLPSSSPI 196
+ H + AP P P +V A P P PP L PPLP
Sbjct: 1001 RPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLP 1060
Query: 197 KTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLH 256
P + P P +L V+ V P T LPPA+
Sbjct: 1061 AAPELLPQFP---SSLATVSASVQSV-------PTQTATLLPPAN--------------- 1095
Query: 257 LPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLP 297
PP+P + PC L EP Q +Q+ PP LP
Sbjct: 1096 -PPLPGGPGIASPCPTVQLTVEPVQEEQASQD---KPPGLP 1132
Score = 32.3 bits (72), Expect = 0.99
Identities = 40/176 (22%), Positives = 60/176 (34%), Gaps = 38/176 (21%)
Query: 262 PPLPLLPPCGYPGLKAEPASPAQDAQEPPAP----PPPLPPYASC--------------- 302
PP+PL Y +P P + +EP A PP LP A+
Sbjct: 567 PPVPLQVQVTYHAQAGQPGPP--EPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTV 624
Query: 303 --SPRASLPAPPLPGVNSSSETP------------PPLPPKSPSFQAPPQKAGAQALPAP 348
++S + L + ++ +P P LP PS A Q A LP
Sbjct: 625 YSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVG 684
Query: 349 PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQP 404
P + P ++ P + PPP+ P + + + QQ P QP
Sbjct: 685 SVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQP---PPLAQP 737
Score = 30.4 bits (67), Expect = 3.7
Identities = 30/121 (24%), Positives = 37/121 (30%), Gaps = 15/121 (12%)
Query: 282 PAQDAQEPPAPPPPLP----PYASCSPRASL-------PAPPLPGVNSSSETPPPLP--- 327
P +A E P P PP P C R + PA P P + P P
Sbjct: 55 PGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADA 114
Query: 328 -PKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTT 386
P+ Q P A A+ PAP G + G + P P R
Sbjct: 115 GPEPVGTQEPGPDPIAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEPE 174
Query: 387 E 387
E
Sbjct: 175 E 175
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 100 bits (249), Expect = 3e-21
Identities = 122/435 (28%), Positives = 160/435 (36%), Gaps = 93/435 (21%)
Query: 6 PPPPP----------LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQ 55
PPPPP L P PLG PP P P + ++ G +A
Sbjct: 497 PPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAG-AAPCPPNPA 555
Query: 56 GTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR 115
+ + ++ R P+ S + T G ++ G T P G AG P P
Sbjct: 556 NSWVPGLSPGGSRRPPR--SPERTLSPSSGYSSQSGTPTLPPKG--LAG--PPASP---- 605
Query: 116 DVAGGKTGQGPGSRAPSPRLPNKTISGPLI--------PPASPRLG-NTSEAHGAARTAP 166
GK R S R P ++S L P S R G G P
Sbjct: 606 ----GKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIP 661
Query: 167 PRPNVPAP--PPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP 224
P P VPAP PPP+ P P P P L + + + PGP++ + A P
Sbjct: 662 PHPKVPAPFSPPPSKPRSPNPAAPALAAPAVV-------PGPVSTTD----------ASP 704
Query: 225 PPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPL--PLLPPCGYPGLKAEPASP 282
PP P T PL + V+S K P PP PPP P PP P + E S
Sbjct: 705 QSPPTPQTTLTPLQESPVIS-KDQSP-------PPSPPPSYHPPPPPTKKPEVVVEAPSA 756
Query: 283 AQDAQEP------PAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336
++ A+EP P PPPP P S A P PP S + P P SP +
Sbjct: 757 SETAEEPLQDPNWPPPPPPAPEEQDLS-MADFP-PPEEAFFSVASPEPAGPSGSPELVSS 814
Query: 337 PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQAT 396
P + + A PPGS +PPPAPPA +P +S +
Sbjct: 815 PAASSSSATALQIQPPGSP------------------DPPPAPPAPAP----ASSAPGHV 852
Query: 397 AWTPTQQPGGQLRNG 411
A P ++P G + G
Sbjct: 853 AKLPQKEPVGCSKGG 867
Score = 79.0 bits (193), Expect = 9e-15
Identities = 116/450 (25%), Positives = 146/450 (32%), Gaps = 94/450 (20%)
Query: 10 PLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRS 69
P PP G P P + PP +SLR S+L + + +DRS
Sbjct: 591 PTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD----PAPSDRS 646
Query: 70 APQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSR 129
PQI L P G R V P +
Sbjct: 647 GPQI-----------------------------------LTPLGDRFVI------PPHPK 665
Query: 130 APSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPP 189
P+P P PP+ PR N + AA P P P PP P P
Sbjct: 666 VPAPFSP---------PPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTP 716
Query: 190 LPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPP--LPPASVLSDKA 247
L S I PP P PP PPPPPT P + A S+ A
Sbjct: 717 LQESPVISKDQSPPPSP----------------PPSYHPPPPPTKKPEVVVEAPSASETA 760
Query: 248 VKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRAS 307
+P P + PP PPP P + A PA P P S +S
Sbjct: 761 EEPLQDP-NWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASS 819
Query: 308 LPAPPLPGVNSSSETPPPLPP-KSPSFQAP------PQK--AGAQALPAPP-----APPG 353
A L S PPP PP +P+ AP PQK G PP AP
Sbjct: 820 SSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLV 879
Query: 354 SQPFLQKKRHGRPGAGGGKLNPP--PAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNG 411
+ LQ R GA GG P P+ P + LS ++ A + +L+
Sbjct: 880 TPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKAC 939
Query: 412 SLHIIDDFESKFTFHSVEDFPPPDEYKPCQ 441
SL + S + + PP E +P Q
Sbjct: 940 SLAASEGLSS-----AQPNGPPEAEPRPPQ 964
Score = 70.5 bits (171), Expect = 3e-12
Identities = 104/391 (26%), Positives = 135/391 (34%), Gaps = 95/391 (24%)
Query: 117 VAGGKTGQGPGSRAPSPRLPNKTISGPLIPP-------ASPRLGNTSEAHG--AARTAPP 167
V+ G T G P + T S ++PP SP G+T+EA + R++
Sbjct: 426 VSDGSTLSSKGGSEGQPE--SSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQ 483
Query: 168 RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPP 227
PPPPP + S + L P GPL PP P P
Sbjct: 484 LSGRSVSLRKLKRPPPPPRR----THSLHQRGLAVPDGPLG-------LPPKPERKQQPQ 532
Query: 228 PPPPPTP--------PPLPPASVLSDKAVKPQLAP--LHLPPIPPPLPLLPPCGYPGLKA 277
P PPT P PP S P L+P PP P L P GY
Sbjct: 533 LPRPPTTGGSEGAGAAPCPPNPANS---WVPGLSPGGSRRPPRSPERTLSPSSGYSSQSG 589
Query: 278 EPASPAQDAQEPPAPP----PPLPPYASC--SPRASLPAPPLPGVNSSSE---------- 321
P P + PPA P PP P + SP AS+ + +SSS+
Sbjct: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQ 649
Query: 322 ---------------------TPPPLPPKSPSFQAPPQKAGA---------QALP-APPA 350
+PPP P+SP+ AP A A A P +PP
Sbjct: 650 ILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPT 709
Query: 351 PPGSQPFLQK-----KRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPG 405
P + LQ+ K P + +PPP PP + P + + S TA P Q P
Sbjct: 710 PQTTLTPLQESPVISKDQSPPPSPPPSYHPPP-PPTKKPEVVVEAPSASETAEEPLQDPN 768
Query: 406 GQLRNGSLHIIDDFESKFTFHSVEDFPPPDE 436
D S+ DFPPP+E
Sbjct: 769 WPPPPPPAPEEQDL-------SMADFPPPEE 792
Score = 62.0 bits (149), Expect = 1e-09
Identities = 98/411 (23%), Positives = 130/411 (31%), Gaps = 61/411 (14%)
Query: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAP----------PVSTDTSSLRRADPKGRSALLAD 52
+PP P P P PPP P P P+AP PVST +S + P L
Sbjct: 660 IPPHPKVPAPFSPPP-SKPRSPNPAAPALAAPAVVPGPVSTTDASPQ--SPPTPQTTLTP 716
Query: 53 IQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA 112
+Q+ + K P K+ AS P PA
Sbjct: 717 LQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPA 776
Query: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVP 172
+ P S P P P SP L ++ A ++ TA +
Sbjct: 777 PEEQDLSMADFPPPEEAFFSVASPE-----PAGPSGSPELVSSPAASSSSATA-----LQ 826
Query: 173 APPPPTPPPPPPPLPPPLPSSSP---IKTPLVSPPGPLTKGNLPVVAPPVPCAPPP---- 225
PP +P PPP P P SS+P K P P G G P P P
Sbjct: 827 IQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQM 886
Query: 226 ------------PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP 273
P P P+ P P LS +A P AP L
Sbjct: 887 VRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRA-SPVPAPSSGLHAAVRLKACSLAASE 945
Query: 274 GLK-AEPASPAQDAQEPPAPPPPLPPY--ASCSPRASLPAPPLPGVNS------------ 318
GL A+P P + PP P + + S + L P P +
Sbjct: 946 GLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRS 1005
Query: 319 -SSETPPPLPPKSPSFQAPPQKAGAQALPAPPAP--PGSQPFLQKKRHGRP 366
S + PP P KSP P + + +P P +P P ++P +G P
Sbjct: 1006 ISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLP 1056
Score = 48.5 bits (114), Expect = 1e-05
Identities = 54/224 (24%), Positives = 74/224 (33%), Gaps = 22/224 (9%)
Query: 2 PVPPPPPPPLPPPPPPLGAPP---PPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58
P P PPP PP P P + P P PV + G + + Q R
Sbjct: 829 PPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVR 888
Query: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTP-PTLGDLFAGGFPVLRPAGQRDV 117
LR V P + S K + + R + P P+ G A A +
Sbjct: 889 LRSVGAPGGAPTPALGPS-APQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGL 947
Query: 118 AGGKTGQGPGSRAPSPRLPNKTISG---------PLIPPASP------RLGNTSEAHGAA 162
+ + P + P+ P T S L P SP + +E +
Sbjct: 948 SSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSIS 1007
Query: 163 RTAPPR--PNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP 204
PP+ P PPP P +PPP S P PL +PP
Sbjct: 1008 EQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPP 1051
Score = 39.7 bits (91), Expect = 0.006
Identities = 51/193 (26%), Positives = 64/193 (33%), Gaps = 34/193 (17%)
Query: 290 PAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALP--- 346
P P LPP + LP PP G S P PP + P G P
Sbjct: 515 PDGPLGLPPKPERKQQPQLPRPPTTG-GSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRS 573
Query: 347 -----APPAPPGSQ---PFLQKKRHGRPGAGGGKLNPPP-------APPARSPTTELSSK 391
+P + SQ P L K P A GK PP P S ++ L+S
Sbjct: 574 PERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSL 633
Query: 392 SQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRS 451
++ P+ + G Q I+ +F PP P P PRS
Sbjct: 634 CSSSSDPAPSDRSGPQ-------ILTPLGDRFVI-------PPHPKVPAPFSPPPSKPRS 679
Query: 452 RTP-GPWLQAEAV 463
P P L A AV
Sbjct: 680 PNPAAPALAAPAV 692
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 97.8 bits (242), Expect = 2e-20
Identities = 130/480 (27%), Positives = 174/480 (36%), Gaps = 60/480 (12%)
Query: 3 VPPPPPPPLPPPPPPLGAPPP-------PPPSAPPVSTDTSSLRRADPKGRSALLADIQQ 55
+PPP PL PPP PP PPP P S +L + P S L ++
Sbjct: 441 LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE 500
Query: 56 GTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR 115
+ +P ES +E S +PP L P +
Sbjct: 501 SP--LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS-------PLSPPFEE 551
Query: 116 DVAGGKTGQGPGSRAP-SPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAP 174
+ P S P + RL P+ PP P S A+R PP P
Sbjct: 552 SPLSPPPEELPTSPPPEASRLSPPPEESPMSPP--PEESPMSPPPEASRLFPPFEESPLS 609
Query: 175 PPP-----TPPPPPPPLPPPLPSSSPI-----KTPLVSPPGPLTKGNLPVV---APPVPC 221
PPP +PPP L PP P SP+ ++P+ PP LPVV +PP
Sbjct: 610 PPPEESPLSPPPEASRLSPP-PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668
Query: 222 APPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPAS 281
+P PPP PT PP P AS LS P+ +P PP P P L E +
Sbjct: 669 SPLSPPPEESPTSPP-PEASRLSP---PPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724
Query: 282 PAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLP-PKSPSFQAPPQKA 340
+EP P P+ S P P P ++ E P P + P P++
Sbjct: 725 LLPLPEEPQLCPRSEGPHLS-------PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEP 777
Query: 341 GAQALPAPP--APPGSQPFLQ---KKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQA 395
A+P P +P P L ++ H P L+P P P SP E S S Q
Sbjct: 778 CLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQ- 836
Query: 396 TAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPG 455
+++P R H+ + E S PP+E P Q P ++P PG
Sbjct: 837 -----SEEPCLSPRPEESHLSPELEKPPL--SPRPEKPPEE--PGQCPAPEELPLFPPPG 887
Score = 93.6 bits (231), Expect = 4e-19
Identities = 92/289 (31%), Positives = 116/289 (40%), Gaps = 48/289 (16%)
Query: 133 PRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPP--------------T 178
P LP S PL PP P TS A+R +PP +PA P P +
Sbjct: 439 PLLPPPEES-PLSPP--PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLS 495
Query: 179 PPPPPPPLPPPLPSS-------SPIKTPLVSPPGPLTKGNL------PVVAPPVPCAPPP 225
PPP PL PP SS SP+ P SPP P + L ++PP +P
Sbjct: 496 PPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLS 555
Query: 226 PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCG--YPGLKAEPASPA 283
PPP PT PP P AS LS P+ +P+ PP P+ P +P + P SP
Sbjct: 556 PPPEELPTSPP-PEASRLSP---PPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSP- 610
Query: 284 QDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343
+E P PPP S P S +PP E P PP S + P ++
Sbjct: 611 -PPEESPLSPPPEASRLSPPPEDSPMSPP-------PEESPMSPPPEVS-RLSPLPVVSR 661
Query: 344 ALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKS 392
P P P S P ++ P +L+PPP SP E S S
Sbjct: 662 LSPPPEESPLSPP--PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708
Score = 92.4 bits (228), Expect = 8e-19
Identities = 115/436 (26%), Positives = 149/436 (34%), Gaps = 73/436 (16%)
Query: 5 PPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQ 64
P PP PP P L P PPP A P+S P + + +RL +
Sbjct: 519 PLSPPEESPPSPALETPLSPPPEASPLSPPFEE-SPLSPPPEELPTSPPPEASRLSPPPE 577
Query: 65 INDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQ 124
+ S P ES S PP LF P + +
Sbjct: 578 ESPMSPPPEESP---------------MSPPPEASRLF--------PPFEESPLSPPPEE 614
Query: 125 GPGSRAP-SPRLPNKTISGPLIPPAS-------PRLGNTSEAHGAARTAPPRPNVPAPPP 176
P S P + RL P+ PP P + S +R +PP P PP
Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
Query: 177 P--TPPPPPP------PLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPP-- 226
P +P PPP P P P+S P + SPP + +LP+ P+ P P
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734
Query: 227 ----------PPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP----IPPPLPLLPPCGY 272
P P P P P LS +A +P L+P P +P L P
Sbjct: 735 CPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794
Query: 273 PGLKAEPAS--PAQDAQEPPAPPPPLPPYASCSPRASLPAPP-----LPGVNSSSETPPP 325
P L +P + +EP P P P S P S +P L S P
Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854
Query: 326 L--PPKSPSFQAPPQKAGAQALP------APPAPPGSQPFLQKKRHGRPGAGGGKLNPPP 377
L PP SP + PP++ G P PP P P L + PG L+P P
Sbjct: 855 LEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE--PPLSPLP 912
Query: 378 APPARSPTTELSSKSQ 393
SP+ E S Q
Sbjct: 913 EELPLSPSGEPSLSPQ 928
Score = 85.1 bits (209), Expect = 1e-16
Identities = 114/424 (26%), Positives = 143/424 (33%), Gaps = 83/424 (19%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSAL--------LAD 52
+P PPP PPP P PPP P+S + R P S L L+
Sbjct: 561 LPTSPPPEASRLSPPPEES-PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP 619
Query: 53 IQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA 112
+ +RL + + S P ES S PP + L PV+
Sbjct: 620 PPEASRLSPPPEDSPMSPPPEESP---------------MSPPPEVSRL--SPLPVV--- 659
Query: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVP 172
RL PL PP P TS A+R +PP + P
Sbjct: 660 --------------------SRLSPPPEESPLSPP--PEESPTSPPPEASRLSPPPEDSP 697
Query: 173 APPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPG-----PLTKGNLPVVAPPVPCAPPPPP 227
PPP P PP L S ++PL+ P P ++G P P P P
Sbjct: 698 TSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPE 757
Query: 228 PP--------PPPTPPPLPP--ASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKA 277
P P +P P P +V + + PQ HL P P L L P P L
Sbjct: 758 EPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP 817
Query: 278 EPASPAQDAQ--EPPAPPPPLPPYASCSPRASLPAPPL--PGVNSSSETPP------PLP 327
P P Q E P P S P S +P L P ++ E PP P P
Sbjct: 818 VPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAP 877
Query: 328 PKSPSFQAPPQKA-----GAQALPAPPAPPGS--QPFLQKKRHGRPGAGGGKLNPPPAPP 380
+ P F P + + G AL P PP S L G P + P P PP
Sbjct: 878 EELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPP 937
Query: 381 ARSP 384
SP
Sbjct: 938 PLSP 941
Score = 84.3 bits (207), Expect = 2e-16
Identities = 90/280 (32%), Positives = 110/280 (39%), Gaps = 38/280 (13%)
Query: 123 GQGPGSRAPS--PRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP 180
GQ G S P+ P GPL A P LG AP +P PPP
Sbjct: 394 GQPKGGHVTSMQPKEP-----GPLQCEAKP-LGKAGVQLEPQLEAPLNEEMPLLPPPEES 447
Query: 181 PPPPPLPPPLPSSSPIKTPLVS-PPGPLTKGNLPV---VAPPVPCAPPPPPPPPPPTPPP 236
P PP P P+S P + +S PP L LP ++ P+ +P PPP P PP
Sbjct: 448 PLSPP-PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506
Query: 237 LPPASVLSDKAVKPQLAPLHLPPIPP-PLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPP 295
P +S S P P PP P PL PP +A P SP +E P PPP
Sbjct: 507 -PESSPFSPLEESPLSPPEESPPSPALETPLSPP-----PEASPLSP--PFEESPLSPPP 558
Query: 296 LPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALP---APPAPP 352
S P AS +PP E P PP S +PP +A P +P +PP
Sbjct: 559 EELPTSPPPEASRLSPP-------PEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611
Query: 353 GSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKS 392
+ L P +L+PPP SP E S S
Sbjct: 612 PEESPLS------PPPEASRLSPPPEDSPMSPPPEESPMS 645
Score = 77.0 bits (188), Expect = 3e-14
Identities = 118/413 (28%), Positives = 144/413 (34%), Gaps = 91/413 (22%)
Query: 2 PVPPPPP--PPLPPP------PPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALL--- 50
P+ PPP P PPP PPP +P PPP P S + P S LL
Sbjct: 670 PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
Query: 51 -----ADIQQGTRLRKVTQINDRS--------APQIESSK-----------GTNKEGGGS 86
+G L + S +PQ E +E S
Sbjct: 730 EEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLS 789
Query: 87 ANTRGASTPPTLGDLFAGGF---PVLRPAGQRDVAGGKTGQG---PGSRAP--SPRLPNK 138
G P +L P L P + + + P S P SPR
Sbjct: 790 PQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEES 849
Query: 139 TISGPLI-PPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPL--PPPLPSSSP 195
+S L PP SPR P +P P P P P PL PP PS SP
Sbjct: 850 HLSPELEKPPLSPR--------------PEKP--PEEPGQCPAPEELPLFPPPGEPSLSP 893
Query: 196 IK-TPLVSPPGPLTKGNLPVVAPPVPCAPPPPPP---PPPPTPPPLPPASVLSDKAVKPQ 251
+ P +S PG LP P P P P PP P PPPL P + A P
Sbjct: 894 LLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP---IITAAAPPA 950
Query: 252 LAPLHLPPIPPPLPLLPPCGYPGLKAEPASP-AQDAQEPPAPPPPLPPYASCSPRASLPA 310
L+PL L P G G ++P SP A E P PPP P +
Sbjct: 951 LSPLG--------ELEYPFGAKG-DSDPESPLAAPILETPISPPPEANCTDPEPVPPMIL 1001
Query: 311 PPLPGVNSSSETP---PPLPPK-SPSFQ-------APPQKAGAQALP-APPAP 351
PP PG +P PLPP+ SP Q +PP + ALP + P+P
Sbjct: 1002 PPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSP 1054
Score = 72.8 bits (177), Expect = 7e-13
Identities = 139/505 (27%), Positives = 164/505 (32%), Gaps = 130/505 (25%)
Query: 5 PPPPPPLPPPPPPLGAPPPPP---PSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
P PP PP P P GAP PP S+ P + P G +
Sbjct: 2190 PTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPP-GTPRHQPSTPDPFLKPR 2248
Query: 62 VTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGK 121
+++ + P+ S G GGG A+ S PP G+ G + G
Sbjct: 2249 CPSLDNLAVPE---SPGV---GGGKASEPLLSPPP-FGESRKALEVKKEELGASSPSYGP 2301
Query: 122 TGQG----PGSRAPSPRLPNKT---ISGPLIP------PASPRLG-NTSEAHGAARTAPP 167
G P S L KT PL P P SP LG E A AP
Sbjct: 2302 PNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPS 2361
Query: 168 RPNVP------------APPPPTPPPPPPP------LPPPLPSSSPIKTPLVSPPG---- 205
P+ P A PP TP P PPP LPP S P SP
Sbjct: 2362 PPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSS 2421
Query: 206 --PLTKGNLPVVA-PPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPP 262
PLT L A P P P P P PP P + + APLH PP P
Sbjct: 2422 QSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS--------RDPFAPLHKPPRPQ 2473
Query: 263 PLPL-----------LPPCGYPGLKAEPASPAQD--AQEPPAPPP--------------P 295
P + L G+P A PA PA + A+ P PP P
Sbjct: 2474 PPEVAFKAGSLAHTSLGAGGFPA--ALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTP 2531
Query: 296 LP-----PYASCSP--RASLPAPPLP---GVNSSSETPPPL------------------- 326
P P A P + +P P LP G+NS P L
Sbjct: 2532 SPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSG 2591
Query: 327 PPKSPSFQAPPQKAGAQALP-----APPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPA 381
P PS + + G L PPAP GS P+L R G P
Sbjct: 2592 SPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGI------TSPVEKR 2645
Query: 382 RSPTTELSSKSQQATAWTP-TQQPG 405
P T + S ATA P TQ PG
Sbjct: 2646 EDPGTGMG--SSLATAELPGTQDPG 2668
Score = 72.4 bits (176), Expect = 9e-13
Identities = 70/244 (28%), Positives = 88/244 (36%), Gaps = 50/244 (20%)
Query: 176 PPTPPPPPPPLPPPL-------PSSSPIKTPLVSPPGPLT-----KGNLPVVAPP----- 218
PP P P P L P + + PGPL G V P
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433
Query: 219 ----VPCAPPP------PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLP 268
+P PPP PPP PT PP P AS LS P L P+P L L
Sbjct: 434 LNEEMPLLPPPEESPLSPPPEESPTSPP-PEASRLS-----PPPEELPASPLPEALHLSR 487
Query: 269 PCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLP---APPLPGVNSSSETPPP 325
P L+ P SP + + P +PPP P++ P +PP P + + PP
Sbjct: 488 P-----LEESPLSPPPE-ESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPE 541
Query: 326 LPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPT 385
P SP F+ P + LP P P S+ P ++PPP SP
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRL--------SPPPEESPMSPPPEESPMSPP 593
Query: 386 TELS 389
E S
Sbjct: 594 PEAS 597
Score = 68.6 bits (166), Expect = 1e-11
Identities = 122/453 (26%), Positives = 158/453 (34%), Gaps = 90/453 (19%)
Query: 11 LPPPPPPLGAPPPPPPSAP---------PVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
+PP P LG+ PPP +AP P TS+ P S D L+
Sbjct: 2106 IPPQPGALGS--PPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKL 2163
Query: 62 VTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTL----GDLFAGGFPVLRPAGQRDV 117
Q+ Q+ S R + PPT A P + A R
Sbjct: 2164 PPQV----PAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPG 2219
Query: 118 AGGKTGQ----GPGSRAPSPRLPNKTISGPLIPPASPRLGNTS--EAHGAARTAPPRPNV 171
A G+ G+ PG+ P P+ P + P P L N + E+ G P +
Sbjct: 2220 A-GQPGEFHTTPPGTPRHQPSTPD-----PFLKPRCPSLDNLAVPESPGVGGGKASEPLL 2273
Query: 172 PAPP----------------PPTPPPPPPPLP-PPLPSSS------PIKTPLVSPPGPLT 208
PP +P PP L PSS +KTP V PLT
Sbjct: 2274 SPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVF-KAPLT 2332
Query: 209 --KGNLPVVAPPVPCAPPPPPP-----PPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIP 261
+ +P + P PPP P PP+ P + +D +P L P PP P
Sbjct: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPP 2392
Query: 262 PPLPLLPPCGYPG--LKAEPASP-AQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNS 318
LPP P PASP +Q + + P P PL A C P+P P S
Sbjct: 2393 ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFC------PSPVTPRFQS 2446
Query: 319 SSE-TPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPP 377
+ PP P+S AP K P P PP H GAGG P
Sbjct: 2447 PDPYSRPPSRPQSRDPFAPLHK------PPRPQPPEVAFKAGSLAHTSLGAGGF----PA 2496
Query: 378 APPARSPTTELSSKSQQATAWTPTQQPGGQLRN 410
A PA P EL +K P+ QP +R+
Sbjct: 2497 ALPA-GPAGELHAK-------VPSGQPPNFVRS 2521
Score = 60.5 bits (145), Expect = 3e-09
Identities = 74/268 (27%), Positives = 97/268 (36%), Gaps = 32/268 (11%)
Query: 161 AARTAPPRPNVPAPPPPTP-PPPPPPLPPPLPSSSP-------------IKTPLVSPPGP 206
A +T P ++ PP P PPP P + SP +K P S PGP
Sbjct: 2094 ARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGP 2153
Query: 207 LTKGNLPVVAPP-VPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPL- 264
+ G L + PP VP P P PL P + P +P P PP L
Sbjct: 2154 DSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLG 2213
Query: 265 -PLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETP 323
P G PG + P +P P P L P C +L P PGV +
Sbjct: 2214 ASSRPGAGQPG-EFHTTPPGTPRHQPSTPDPFLKP--RCPSLDNLAVPESPGVGGGKASE 2270
Query: 324 PPL--PPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPA 381
P L PP S +A K +P P + F+ G GG +L P
Sbjct: 2271 PLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSG-THLGGLELKTPDV--F 2327
Query: 382 RSPTTELSSKSQQATAWTPTQQPGGQLR 409
++P T +S+ + Q PG LR
Sbjct: 2328 KAPLTPRASQVE-------PQSPGLGLR 2348
Score = 54.3 bits (129), Expect = 2e-07
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 222 APPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLL--PPCGYPGLKAEP 279
APPP P PPP+P PAS ++ V+ PL PP+P PLPL P P +A P
Sbjct: 4908 APPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967
Query: 280 ASPAQDAQEP 289
+D++ P
Sbjct: 4968 PEEGEDSRPP 4977
Score = 53.1 bits (126), Expect = 5e-07
Identities = 91/382 (23%), Positives = 127/382 (33%), Gaps = 43/382 (11%)
Query: 5 PPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQ 64
PP P P PL PP P P P V+ SL G A + G +
Sbjct: 2453 PPSRPQSRDPFAPLHKPPRPQP--PEVAFKAGSLAHTS-LGAGGFPAALPAGPAGELHAK 2509
Query: 65 INDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA----GQRDVAGG 120
+ P S GT G + R + P +G+ P L+P G G
Sbjct: 2510 VPSGQPPNFVRSPGTGAFVGTPSPMR-FTFPQAVGE------PSLKPPVPQPGLPPPHGI 2562
Query: 121 KTGQGPGSRAPSPRLPNKTISG----PLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPP 176
+ GPG P+ N T++ P P P G+T E++G + PP PP
Sbjct: 2563 NSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPS----VLPP 2618
Query: 177 PTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTP-P 235
P P P L S I +P+ P T + +P P T
Sbjct: 2619 PAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELE 2678
Query: 236 PLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPC-GYPGL-KAEPASPAQDAQEPPAPP 293
L + ++ Q+ L G PG AEP+SPA + P
Sbjct: 2679 KQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTP 2738
Query: 294 PPLPPYASCSPRASLPAPP-------------LPGVNSSSETPPPLPPKSPSFQAPPQKA 340
+A ++SL P P + S PPP P S +
Sbjct: 2739 -----FAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVG 2793
Query: 341 GAQALPAPPAPPGSQPFLQKKR 362
G+QA PGS P Q+++
Sbjct: 2794 GSQAFYQRAPYPGSLPLQQQQQ 2815
Score = 52.4 bits (124), Expect = 9e-07
Identities = 103/418 (24%), Positives = 125/418 (29%), Gaps = 100/418 (23%)
Query: 4 PPPPPPPLPPPP------PPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
P P PL PPP P LG P P PP+S L + P G +L +
Sbjct: 875 PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS-PSGEPSLSPQLMPPD 933
Query: 58 RLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLF-AGGFPVLRPAGQRD 116
L PP L + A P L P G+ +
Sbjct: 934 PL-----------------------------------PPPLSPIITAAAPPALSPLGELE 958
Query: 117 VAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPP 176
G G P L + P+ PP P T PP P P P
Sbjct: 959 YPFGAKGDSD----PESPLAAPILETPISPP--PEANCTDPEPVPPMILPPSPGSPVGPA 1012
Query: 177 ------PTPP---------------------PPPPPLPPPLPSSSPIKTPLVSPPGPLTK 209
P PP PP PL P P S K VS L +
Sbjct: 1013 SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHE 1072
Query: 210 GNLPVVAPPVPCAPPPPPPPPPPTP------PPLPPASVLSD-KAVKPQLAPLHLPPIPP 262
V+ P A P P P+P P PA L D + APL P
Sbjct: 1073 METEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPG 1132
Query: 263 PLPLLPPCGYPGLKAE--PASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSS 320
P P PG A SP E AP P+ Y C A +P
Sbjct: 1133 SQP--EPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSP----CEEQE 1186
Query: 321 ETPPPLPPKSPSF---QAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPG-AGGGKLN 374
E P+ P P+ + + A + PGS+P L G P GGG L+
Sbjct: 1187 EPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLL-----GSPDPEGGGSLS 1239
Score = 51.6 bits (122), Expect = 2e-06
Identities = 83/323 (25%), Positives = 107/323 (33%), Gaps = 51/323 (15%)
Query: 107 PVLRPAGQRD--------VAGGKTGQ-GPGSRAPSPRLPNKTISGPLIPPASPRLGNTSE 157
P LR GQ+ GG GQ G GS + + +P+ L+ S LG+
Sbjct: 4093 PPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPH------LLAQPSVSLGDQPG 4146
Query: 158 AHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAP 217
+ P +P + P P PP P L S + + P + L V
Sbjct: 4147 SMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLA 4206
Query: 218 PVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPP-PLPLLPPC-----G 271
P P L + +AV+ Q P P PL L C G
Sbjct: 4207 KNPQLRHLSPQQQQQLQALLMQRQLQQSQAVR-QTPPYQEPGTQTSPLQGLLGCQPQLGG 4265
Query: 272 YPGLKAEPASPAQDAQEPPAPPP-PLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKS 330
+PG + P P PP P PP A + P P P +S E P S
Sbjct: 4266 FPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS 4325
Query: 331 PSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPP---APPARSPTTE 387
PS Q P + PP PG+ P G L PPP +P A
Sbjct: 4326 PSSQLPTE------AQLPPTHPGT-----------PKPQGPTLEPPPGRVSPAAAQLADT 4368
Query: 388 LSSKSQQATAWTP------TQQP 404
L SK W P TQ+P
Sbjct: 4369 LFSKG--LGPWDPPDNLAETQKP 4389
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
Query: 227 PPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDA 286
P P PPT +S+ V+ AP P PPP PL P P + P +
Sbjct: 4884 PAPEPPTQHSY--TYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPL 4941
Query: 287 QEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPP 325
EPP P P P AS SP ++ P P ++ PP
Sbjct: 4942 AEPPVPSP--LPLAS-SPESARPKPRARPPEEGEDSRPP 4977
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/62 (37%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 175 PPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTP 234
PPP P PPP P P+S P + + P PL + P V P+P A P P P
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE---PPVPSPLPLASSPESARPKPRA 4965
Query: 235 PP 236
P
Sbjct: 4966 RP 4967
Score = 38.5 bits (88), Expect = 0.014
Identities = 55/242 (22%), Positives = 85/242 (35%), Gaps = 32/242 (13%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPP-----------PPSAPPVSTDTSSLRRADPKGRSAL 49
M +PP P P+ P P L P PP P ++PP +L + P S +
Sbjct: 999 MILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPI 1058
Query: 50 --LADIQQGTRLRKV--TQINDRSAPQIE-SSKGTNKEGGGSANTRGASTPPTLGDLFAG 104
+ + L ++ ++++ P +E S+ G + S P L D F+G
Sbjct: 1059 GKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDD-FSG 1117
Query: 105 GFPVLRPAGQRDVAGG--KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAA 162
P D G + GQ PGS A + + + P +P + E A
Sbjct: 1118 LGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTP-MEVYPECKQTA 1176
Query: 163 RTAPPRPNVPAPPPPTPPPPPPPLPPPL------------PSSSPIKTPLVSPPGPLTKG 210
P P P P PP + + +S P PL+ P P G
Sbjct: 1177 GQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGG 1236
Query: 211 NL 212
+L
Sbjct: 1237 SL 1238
Score = 37.7 bits (86), Expect = 0.023
Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 9/88 (10%)
Query: 154 NTSEAHGAARTAPP--RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGN 211
N S +APP P+ PP+P P P PP P PL PP P
Sbjct: 4897 NVSNLDVRQLSAPPPEEPSP----PPSPLAPSPASPPTEPLVELPTEPLAEPPVP---SP 4949
Query: 212 LPVVAPPVPCAPPPPPPPPPPTPPPLPP 239
LP+ + P P P PP PP
Sbjct: 4950 LPLASSPESARPKPRARPPEEGEDSRPP 4977
Score = 36.6 bits (83), Expect = 0.052
Identities = 91/393 (23%), Positives = 124/393 (31%), Gaps = 54/393 (13%)
Query: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVT 63
PP PP LPP PPP P A + L D + L +
Sbjct: 4619 PPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLA 4678
Query: 64 QINDRSAPQIESSKGTNKEGGGSANTR-GASTPPTLGDLFAGGFPVLRPAGQRDVAGGKT 122
+ Q E + + E S ++ AS+P ++ A FP L G+
Sbjct: 4679 ALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHL--------GSGRW 4730
Query: 123 GQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPP 182
Q RA SP +P LIP AS + ++ +GA VP P T
Sbjct: 4731 EQE--DRALSPVIP-------LIPRASIPVFPDTKPYGALGL-----EVPGKLPVTT--- 4773
Query: 183 PPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP-------PPPPPPPPTPP 235
S + + + G + VA + P P P T P
Sbjct: 4774 ---WEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEP 4830
Query: 236 PLPPASVLSDK-----AVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPP 290
A K P P L LP GY LK++ + QE P
Sbjct: 4831 KKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLP-----GYT-LKSQLDILSLLKQESP 4884
Query: 291 APPPPLPPYASCSP------RASLPAPPLPGVNSSSETPPPL-PPKSPSFQAPPQKAGAQ 343
AP PP + + + S P P P S P P PP P + P +
Sbjct: 4885 APEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP 4944
Query: 344 ALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPP 376
+P+P S + K RP G PP
Sbjct: 4945 PVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
Score = 36.6 bits (83), Expect = 0.052
Identities = 27/78 (34%), Positives = 34/78 (43%), Gaps = 7/78 (8%)
Query: 6 PPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSAL-LADIQQGT----RLR 60
PPP PPP PL P PP+ P V T L A+P S L LA + R R
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPL--AEPPVPSPLPLASSPESARPKPRAR 4966
Query: 61 KVTQINDRSAPQIESSKG 78
+ D P+++ KG
Sbjct: 4967 PPEEGEDSRPPRLKKWKG 4984
Score = 33.9 bits (76), Expect = 0.34
Identities = 35/145 (24%), Positives = 53/145 (36%), Gaps = 10/145 (6%)
Query: 218 PVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQL-------APLHLPPIPPPLPLLPPC 270
P P P PPP P ASVL + VKP++ +P P + P
Sbjct: 3091 PGPLGPEERPPPAADASEPRL-ASVLPE--VKPKVEEGGRHPSPCQFTIATPKVEPAPAA 3147
Query: 271 GYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKS 330
GL +P +++ P + +AS A P + + +P P S
Sbjct: 3148 NSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGS 3207
Query: 331 PSFQAPPQKAGAQALPAPPAPPGSQ 355
+ ++GA LP PA G +
Sbjct: 3208 SLLEKFELESGALTLPGGPAASGDE 3232
Score = 32.7 bits (73), Expect = 0.75
Identities = 66/243 (27%), Positives = 79/243 (32%), Gaps = 35/243 (14%)
Query: 7 PPPPLPPPPPPLGAPPP------PPPSAPPVSTDTSS----------LRRADPKGRSALL 50
PP L P G+ P PPP A P S D +S +RA G L
Sbjct: 2752 PPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQ 2811
Query: 51 ADIQQ---------GTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTR-GASTPPTLGD 100
QQ T +R S P E + +TR P G
Sbjct: 2812 QQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGP 2871
Query: 101 LFAGGFPVLRPAGQRDVAGGKT---GQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSE 157
F LR Q+ + G T GQGP R PR + + P R S
Sbjct: 2872 AGPAQFIELRHNVQKGLGPGGTPFPGQGPPQR---PRFYPVSEDPHRLAPEGLRGLAVSG 2928
Query: 158 AHGAARTAPPRPNVPAPPPPTPPPPPPPLPP--PLPSSSPIKTPLVSP-PGPLTKGNLPV 214
+APP P + PTP P LP L + P T L P P L G LP
Sbjct: 2929 LPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPC 2988
Query: 215 VAP 217
P
Sbjct: 2989 EDP 2991
Score = 32.3 bits (72), Expect = 0.99
Identities = 21/52 (40%), Positives = 24/52 (46%), Gaps = 6/52 (11%)
Query: 2 PVPPPPP---PPLPPPPPPLGAPPPPPPSAPPVSTD---TSSLRRADPKGRS 47
P PPP P P PP PL P P + PPV + SS A PK R+
Sbjct: 4914 PSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965
Score = 31.2 bits (69), Expect = 2.2
Identities = 49/193 (25%), Positives = 65/193 (33%), Gaps = 41/193 (21%)
Query: 197 KTPLVSPPGPLTKGNLPVVAP-PVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPL 255
K+ LV P G P++ P P PPPP TP + V S + V A
Sbjct: 2745 KSSLVGLPPSKLSG--PILGPGSFPSDDRLSRPPPPATPSSM---DVNSRQLVGGSQAFY 2799
Query: 256 HLPPIPPPLPLLPPCGYPGLKAEPASP-----AQDAQEPPAPPPPLPPYASCSPRASLPA 310
P P LPL + + + A A+ P P P L A SP A +
Sbjct: 2800 QRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGI-- 2857
Query: 311 PPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAG- 369
S+ P P P P P G F++ + + + G G
Sbjct: 2858 --------STRLPGPGEPV-------------------PGPAGPAQFIELRHNVQKGLGP 2890
Query: 370 GGKLNPPPAPPAR 382
GG P PP R
Sbjct: 2891 GGTPFPGQGPPQR 2903
Score = 30.0 bits (66), Expect = 4.9
Identities = 18/40 (45%), Positives = 18/40 (45%), Gaps = 14/40 (35%)
Query: 203 PPGP------LTKGNLPVVAPPVPCAPPPPPPPPPPTPPP 236
P GP LTK NL PP PP PPTPPP
Sbjct: 4601 PTGPDYYSQLLTKNNLS--------NPPTPPSSLPPTPPP 4632
Score = 29.3 bits (64), Expect = 8.3
Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 8/65 (12%)
Query: 1 MPVPPPPPPPLPPPPP----PLGAPPPPPPSAPPVSTDTSSLRRADPKG----RSALLAD 52
+P P PP+P P P P A P P P D+ R KG R LL
Sbjct: 4936 LPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLT 4995
Query: 53 IQQGT 57
IQ+G+
Sbjct: 4996 IQKGS 5000
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 97.8 bits (242), Expect = 2e-20
Identities = 88/268 (32%), Positives = 103/268 (38%), Gaps = 50/268 (18%)
Query: 126 PGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPP 185
PG + P P L N +PP P + PP P P PP PP P P
Sbjct: 228 PGVKRPPPPLMNG------LPPRPP----------LPESLPPPPPGGLPLPPMPPTGPAP 271
Query: 186 LPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSD 245
PP P P P V PP P+ V PP P PP P PP P PP S +
Sbjct: 272 SGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHP 331
Query: 246 KA--VKPQLAPLHLPPIP---PPLP-LLPPCGYPGLKAEPAS----------PAQDAQEP 289
A V P +H PP P PP P + PP PG+ P++ PA A P
Sbjct: 332 PAPGVHPPAPGVH-PPAPGVHPPAPGVHPPA--PGVHPPPSAGVHPQAPGVHPAAPAVHP 388
Query: 290 PAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPP 349
AP PP P+A P PGV+ S+ P PP P G P P
Sbjct: 389 QAPGVH-PPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPP-----GVHPSNPGVH--PPTP 440
Query: 350 APPGSQPFLQKKRHGRPGAGGGKLNPPP 377
PP +P L P G G + PPP
Sbjct: 441 MPPMLRPPL-------PSEGPGNIPPPP 461
Score = 94.4 bits (233), Expect = 2e-19
Identities = 79/237 (33%), Positives = 90/237 (37%), Gaps = 26/237 (10%)
Query: 159 HGAARTAPPRPNVPAPPPPTPPPPPP-----PLPPPLPSSSPIKTPLVSPPGPLTKGNLP 213
H P P++PA PP PPPP P PPLP S P PPG L +P
Sbjct: 211 HFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLP-----PPPPGGLPLPPMP 265
Query: 214 VVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKA--VKPQLAPLHLPPIPPPLPLLPPCG 271
P P PP PP PPP P PPA V+ A V P +H PP P P P
Sbjct: 266 PTGP-APSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVH-PPAPGVHPPAPGVH 323
Query: 272 YPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPP---LPP 328
P P +P PPAP PP P A PP PGV+ PPP + P
Sbjct: 324 PPTSGVHPPAPGV---HPPAPGVH-PPAPGVHPPAPGVHPPAPGVH-----PPPSAGVHP 374
Query: 329 KSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPT 385
++P QA P PG P PG P PP P+
Sbjct: 375 QAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPS 431
Score = 74.7 bits (182), Expect = 2e-13
Identities = 87/309 (28%), Positives = 98/309 (31%), Gaps = 82/309 (26%)
Query: 5 PPPPPPLPPPPPPLGAPPPP-----------PPSAPPVSTDTSSLRRADPKGRSALLADI 53
PP PP LP PP + PPPP P S PP L P G
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTG-------- 268
Query: 54 QQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAG---GFPVLR 110
AP G PP L G PV+
Sbjct: 269 ---------------PAPS------------------GPPGPPQLPPPAPGVHPPAPVVH 295
Query: 111 PAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAH-GAARTAPPRP 169
P A G PG P+P + PPA TS H A PP P
Sbjct: 296 PP-----ASGVHPPAPGVHPPAPGVH---------PPAPGVHPPTSGVHPPAPGVHPPAP 341
Query: 170 NVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPP 229
V PP P PP P + PP P P + V P P P V P P PP P
Sbjct: 342 GV-HPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGM 400
Query: 230 PPPTP--PPLPPASVLSDKAVKPQLAPLH--LPPIPPPLPLLPPCGYPGLKAEPASPAQD 285
P P P PP S V PQ +H P + PP P+ P P P++
Sbjct: 401 HPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPP-------MLRPPLPSEG 453
Query: 286 AQEPPAPPP 294
P PPP
Sbjct: 454 PGNIPPPPP 462
Score = 66.6 bits (161), Expect = 5e-11
Identities = 73/253 (28%), Positives = 91/253 (35%), Gaps = 34/253 (13%)
Query: 2 PVPP-----PPPPPLP---PPPPPLGAP-PPPPPSAPPVSTDTSSLRRADPKGRSALLAD 52
P PP PP PPLP PPPPP G P PP PP+ P S + P A
Sbjct: 233 PPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAP 292
Query: 53 IQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA 112
+ ++ ++ + G + G PPT G V PA
Sbjct: 293 V-----------VHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSG--------VHPPA 333
Query: 113 -GQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV 171
G A G PG P+P + + G PP++ H AA P+
Sbjct: 334 PGVHPPAPGVHPPAPGVHPPAPGV-HPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPG 392
Query: 172 PAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP---PPPPP 228
PP P P P + P P P P V P P + P V PP P P PP P
Sbjct: 393 VHPPAPGMHPQAPGVHPQPPGVHP-SAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPS 451
Query: 229 PPPPTPPPLPPAS 241
P PP PP +
Sbjct: 452 EGPGNIPPPPPTN 464
Score = 64.7 bits (156), Expect = 2e-10
Identities = 69/242 (28%), Positives = 92/242 (38%), Gaps = 28/242 (11%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
+P PP P LPPPPP PP PP+ P S + P A +
Sbjct: 241 LPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPV------- 293
Query: 61 KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA-GQRDVAG 119
++ ++ + G + G PPT G + V PA G A
Sbjct: 294 ----VHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSG-VHPPAPGVHPPAPGVHPPAP 348
Query: 120 GKTGQGPGSRAPSPRLPNKTISG-----PLIPPASPRLGNTSEAHGAARTAP-PRPNVPA 173
G PG P+P + +G P + PA+P + +A G AP P P
Sbjct: 349 GVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAV--HPQAPGVHPPAPGMHPQAPG 406
Query: 174 --PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP 231
P PP P P + P P P P V PP P+ P++ PP+P P PPPP
Sbjct: 407 VHPQPPGVHPSAPGVHPQPPGVHP-SNPGVHPPTPMP----PMLRPPLPSEGPGNIPPPP 461
Query: 232 PT 233
PT
Sbjct: 462 PT 463
Score = 57.0 bits (136), Expect = 4e-08
Identities = 47/134 (35%), Positives = 51/134 (38%), Gaps = 28/134 (20%)
Query: 258 PPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPP--LPPYASCSPRASLPAPPLPG 315
PP PP LP G PG+K P P PP PP P LPP P LP PP+P
Sbjct: 217 PPAPPSLP----AGPPGVKRPP--PPLMNGLPPRPPLPESLPP----PPPGGLPLPPMPP 266
Query: 316 VN---SSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGK 372
S PP LPP +P P A P PG P PG
Sbjct: 267 TGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHP-------PAPGV---- 315
Query: 373 LNPPPAPPARSPTT 386
PPAP PT+
Sbjct: 316 --HPPAPGVHPPTS 327
>gi|40807452 peroxisome proliferator-activated receptor gamma,
coactivator-related 1 [Homo sapiens]
Length = 1664
Score = 97.4 bits (241), Expect = 2e-20
Identities = 125/445 (28%), Positives = 164/445 (36%), Gaps = 76/445 (17%)
Query: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKV 62
+PP P P P L P P PV R DP R ++ G+ + +
Sbjct: 653 LPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDP--RRGAVSSALGGSAPQLL 710
Query: 63 TQINDRSAPQI------ESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRD 116
+ P+ E E G SA T A P L + R Q +
Sbjct: 711 VESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRP----LSLSEYRRRRQQRQAE 766
Query: 117 VAGGKTGQGPGSRAPS-PRLPNKTISGP--LIPPASPRLGNTSEAHGAARTAPPRPN--- 170
++ Q P + PS P P P +IPPA + A + +P P
Sbjct: 767 TEE-RSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAK-------KTALQRSPETPLEIC 818
Query: 171 -VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPV--VAPPVPCAP---- 223
VP P P P P PP+ P+ SS + P P L + + PV V+P VP P
Sbjct: 819 LVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMP-LLARPSPPVQSVSPAVPTPPSMSA 877
Query: 224 -----------PPPPPPPPPTPPPLPPAS--VLSDKAVK----------PQLAPLHLPPI 260
PP PPPP PP LP + VL D P ++P P +
Sbjct: 878 ALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCL 937
Query: 261 PPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPP-PLPPYASCSPRASLPAPPLP--GVN 317
PPP + G PG A P + P APPP P+ PY+S L P P
Sbjct: 938 PPPPTVPLVSGTPGAYAVPPT----CSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPF 993
Query: 318 SSSETPPPLPPKSPSFQAPPQKAGAQALPAPP---------APPGSQPFLQKKRHGRPGA 368
S+ PPPLPP S P K ++ PA P APP S L HG P
Sbjct: 994 WSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLS---LGLPGHGAPQT 1050
Query: 369 GGGKLNPPPAPPARSPTTELSSKSQ 393
K+ P P + P ++S+ Q
Sbjct: 1051 EPTKVEVKPVPASPHPKHKVSALVQ 1075
Score = 45.8 bits (107), Expect = 9e-05
Identities = 103/438 (23%), Positives = 144/438 (32%), Gaps = 71/438 (16%)
Query: 1 MPVPPPPPPPLPPPPPPLGAPP--PPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58
+P PP LP P LG PP PPPP PP + DP A L
Sbjct: 869 VPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPS------ 922
Query: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGA-STPPTLGDLFAGGFPVLRPAGQRDV 117
++ P + G T GA + PPT +A + P
Sbjct: 923 WPCYPHVSPSGYPCLPPPPTVPLVSG----TPGAYAVPPTCSVPWAPPPAPVSPYSS-TC 977
Query: 118 AGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPP 177
G G GPG P T+ P +PPAS +G A P+P + + P
Sbjct: 978 TYGPLGWGPG---PQHAPFWSTVPPPPLPPAS--IGR----------AVPQPKMESRGTP 1022
Query: 178 TPPPP---PPPLPPPL---------PSSSPIKT---PLVSPPGPLTKGNLPVVAP---PV 219
PP P + PPL P + P K P+ + P P K + V +P +
Sbjct: 1023 AGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKAL 1082
Query: 220 PCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIP-----PPLPLLPPCGYPG 274
C P L P + + KP L P P P LP + P
Sbjct: 1083 ACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRK 1142
Query: 275 LKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQ 334
L P Q +++ + + S + L SE PP +P+
Sbjct: 1143 LSFLPTPRTQGSED------VVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADS 1196
Query: 335 APPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPAR--SPTTELS--- 389
+G +P P + A L PP PP + P +S
Sbjct: 1197 LAVGNSGGVDIPQEKRP-------LDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLA 1249
Query: 390 -SKSQQATAWTPTQQPGG 406
+KS ++TA T +P G
Sbjct: 1250 KAKSPKSTAQEGTLKPEG 1267
Score = 32.7 bits (73), Expect = 0.75
Identities = 42/173 (24%), Positives = 62/173 (35%), Gaps = 32/173 (18%)
Query: 233 TPPPLPPASVL------------SDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPA 280
TPP PA V+ D +KP L+ L P PP PPC EP
Sbjct: 1304 TPPKKMPALVIPEVGSRWNVKRHQDITIKPVLS---LGPAAPP----PPC--IAASREPL 1354
Query: 281 SPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKA 340
+++ P L P + SP AS P N + PP P +KA
Sbjct: 1355 DHRTSSEQADPSAPCLAPSSLLSPEAS------PCRNDMNTRTPPEPSAKQRSMRCYRKA 1408
Query: 341 GAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQ 393
A P+ G ++ R+ R + G + + S ++ S+S+
Sbjct: 1409 CRSASPSSQGWQG-----RRGRNSRSVSSGSNRTSEASSSSSSSSSSSRSRSR 1456
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 96.7 bits (239), Expect = 4e-20
Identities = 136/509 (26%), Positives = 176/509 (34%), Gaps = 101/509 (19%)
Query: 27 SAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR-KVTQINDRSAPQIESSKGTNKEGGG 85
SA V + SS +++ + R + +D ++ R K T+ + S P S
Sbjct: 78 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSR 137
Query: 86 SANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPL- 144
S N G+S P + P + + + Q +A P L T P
Sbjct: 138 SVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP 197
Query: 145 --IPPASPRL---GNTSEAHGA-------ARTAPPRPNVPAPPPPT----------PPPP 182
PP +P+L G T A A AP +P P P P P P
Sbjct: 198 SSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRP 257
Query: 183 PPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPP-----------PPP 231
P P PPP PS P PL G + + P A P PP P P P
Sbjct: 258 PSPHPPPHPSPHPPLQPLTGSAG---QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 314
Query: 232 PTPPPLPPASVLSDKAV--KPQLAPLHL---------------PPIPPPLPLLPPCGYPG 274
P P LPP + + P A H PP PLP P P
Sbjct: 315 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP-LAMPH 373
Query: 275 LKAEPASPAQDAQEPPAP--PPPLPPYASCSPRASLPAPPLPGVNSSSET-------PPP 325
+K P +P P A PP L + S A+LP PP SS T PPP
Sbjct: 374 IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 433
Query: 326 L---PPKSPSFQAPPQKAG---AQALPAPPA--PP-------GSQPFLQKKRHGRPGAGG 370
L P P +P Q G +Q LP PPA PP PF Q P G
Sbjct: 434 LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ-----HPFVPG 488
Query: 371 GKLNPPPAPPARSPTTELSSKSQQATAWTP---TQQPGGQLRNGSLHIIDDFESKFTFHS 427
G PPP P P+T +A P GG + GS + + K +
Sbjct: 489 G---PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK--EEA 543
Query: 428 VEDFPPPDEYKPCQKIYPSKIPRSRTPGP 456
++D P+ P PRS +P P
Sbjct: 544 LDDAEEPES--------PPPPPRSPSPEP 564
Score = 87.0 bits (214), Expect = 3e-17
Identities = 121/450 (26%), Positives = 165/450 (36%), Gaps = 100/450 (22%)
Query: 21 PPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTN 80
P P P++ D S R P S D + T + ++ + ++ ++S+K
Sbjct: 38 PASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQR 97
Query: 81 KEGGGSANT--RGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNK 138
++ R +S ++ P G+ + + ++ GS P +
Sbjct: 98 EKVASDTEEADRTSSKKTKTQEISRPNSP---SEGEGESSDSRSVNDEGSSDPKDIDQDN 154
Query: 139 TISGPLIPPASPRLGNTSEAHGAAR-----TAPPRPNVPA---PPPPTPPPPPPPLPPPL 190
+ P IP SP+ N S++ +A+ PP P P P + PP P LP P
Sbjct: 155 RSTSPSIP--SPQ-DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG 211
Query: 191 PSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPP-------------------PPPPPP 231
P+ S P P G T P P P AP P PPP P
Sbjct: 212 PTPSATAVP---PQGSPTASQAPN-QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 267
Query: 232 PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPA 291
P PP P L+ A +P AP H PPL P G L+A P + P
Sbjct: 268 PHPPLQP----LTGSAGQPS-APSH---AQPPLHGQGPPGPHSLQAGP------LLQHPG 313
Query: 292 PPPP--LPPYAS-------CSPRASLP--APPLPGVNSS--SETPP---PLPP------- 328
PP P LPP AS SP A+ P + LP S+ S+ PP PLPP
Sbjct: 314 PPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 373
Query: 329 -KSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPA--------- 378
K P PQ QA PP G PF + L PPPA
Sbjct: 374 IKPPPTTPIPQLPAPQAHKHPPHLSGPSPF----------SMNANLPPPPALKPLSSLST 423
Query: 379 ---PPARSPTTELSSKSQQATAWTPTQQPG 405
P A P +L +SQ + +P Q PG
Sbjct: 424 HHPPSAHPPPLQLMPQSQPLPS-SPAQPPG 452
Score = 85.9 bits (211), Expect = 8e-17
Identities = 115/411 (27%), Positives = 143/411 (34%), Gaps = 67/411 (16%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALL--ADIQQGTRL 59
P P PP P P P P P + PP + T+S P+ +A + IQQ L
Sbjct: 195 PAPSSAPPGTPQLPTP--GPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 252
Query: 60 RKVTQINDRSAPQIESSKGTNKEGG--GSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117
+ P G G + + PP G P G +
Sbjct: 253 HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ---------GPPGPHSL 303
Query: 118 AGGKTGQGPGSRAPSPRLPNKTISG--PLIPPASPRLGNTSEAHGAARTA-----PPRPN 170
G Q PG P LP + G PL + +TS A+++A PPR
Sbjct: 304 QAGPLLQHPGPPQPF-GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 362
Query: 171 VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP 230
P PP P P PPP TP+ P P + P ++ P P + PP
Sbjct: 363 ---PLPPAPLAMPHIKPPP-------TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP- 411
Query: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPPI--PPPLPLLPPCGYPGLKAEPASPAQDAQE 288
PP L P S LS H PP PPPL L+P L + PA P Q
Sbjct: 412 ---PPALKPLSSLS----------THHPPSAHPPPLQLMPQS--QPLPSSPAQPPGLTQS 456
Query: 289 PPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPL-PPKSPSFQAPPQKAGAQALP- 346
PPPP + P PP PPP+ PP PS PP G A P
Sbjct: 457 QNLPPPP-ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP 515
Query: 347 --APPAPPGS--------QPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTE 387
A GS P +Q K A + P PP RSP+ E
Sbjct: 516 CSGAAASGGSIAGGSSCPLPTVQIKEEALDDA---EEPESPPPPPRSPSPE 563
Score = 48.1 bits (113), Expect = 2e-05
Identities = 75/299 (25%), Positives = 101/299 (33%), Gaps = 74/299 (24%)
Query: 5 PPPPPPL--------PPPPPPLGAPPPPPPSAPPVSTDTSSLRRAD----PKGRSALLAD 52
PP P L P PP P G PP P+ T ++ P +SAL +
Sbjct: 297 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQS- 355
Query: 53 IQQGTRLRKV---------------TQINDRSAPQIESSKGTNKEGGGSANTRGASTPPT 97
QQ R + + T I APQ + K G S + A+ PP
Sbjct: 356 -QQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ--AHKHPPHLSGPSPFSMNANLPPP 412
Query: 98 LGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSE 157
P L+P ++ T P + P +L ++ P P P L +
Sbjct: 413 ---------PALKP-----LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 458
Query: 158 AHGAARTAPP--------------RPNVPAPPPPTPPP--PPPPLPPPLPSSS--PIKTP 199
+ PP P VP PPP PP P PP P +S P +
Sbjct: 459 LPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 518
Query: 200 LVSPPGPLTKGN---LPVVA--------PPVPCAPPPPPPPPPPTPPPLPPASVLSDKA 247
+ G + G+ LP V P +PPPPP P P P + S S A
Sbjct: 519 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSA 577
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 96.7 bits (239), Expect = 4e-20
Identities = 136/509 (26%), Positives = 176/509 (34%), Gaps = 101/509 (19%)
Query: 27 SAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR-KVTQINDRSAPQIESSKGTNKEGGG 85
SA V + SS +++ + R + +D ++ R K T+ + S P S
Sbjct: 632 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSR 691
Query: 86 SANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPL- 144
S N G+S P + P + + + Q +A P L T P
Sbjct: 692 SVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP 751
Query: 145 --IPPASPRL---GNTSEAHGA-------ARTAPPRPNVPAPPPPT----------PPPP 182
PP +P+L G T A A AP +P P P P P P
Sbjct: 752 SSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRP 811
Query: 183 PPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPP-----------PPP 231
P P PPP PS P PL G + + P A P PP P P P
Sbjct: 812 PSPHPPPHPSPHPPLQPLTGSAG---QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 868
Query: 232 PTPPPLPPASVLSDKAV--KPQLAPLHL---------------PPIPPPLPLLPPCGYPG 274
P P LPP + + P A H PP PLP P P
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP-LAMPH 927
Query: 275 LKAEPASPAQDAQEPPAP--PPPLPPYASCSPRASLPAPPLPGVNSSSET-------PPP 325
+K P +P P A PP L + S A+LP PP SS T PPP
Sbjct: 928 IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 987
Query: 326 L---PPKSPSFQAPPQKAG---AQALPAPPA--PP-------GSQPFLQKKRHGRPGAGG 370
L P P +P Q G +Q LP PPA PP PF Q P G
Sbjct: 988 LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ-----HPFVPG 1042
Query: 371 GKLNPPPAPPARSPTTELSSKSQQATAWTP---TQQPGGQLRNGSLHIIDDFESKFTFHS 427
G PPP P P+T +A P GG + GS + + K +
Sbjct: 1043 G---PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK--EEA 1097
Query: 428 VEDFPPPDEYKPCQKIYPSKIPRSRTPGP 456
++D P+ P PRS +P P
Sbjct: 1098 LDDAEEPES--------PPPPPRSPSPEP 1118
Score = 87.0 bits (214), Expect = 3e-17
Identities = 121/450 (26%), Positives = 165/450 (36%), Gaps = 100/450 (22%)
Query: 21 PPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTN 80
P P P++ D S R P S D + T + ++ + ++ ++S+K
Sbjct: 592 PASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQR 651
Query: 81 KEGGGSANT--RGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNK 138
++ R +S ++ P G+ + + ++ GS P +
Sbjct: 652 EKVASDTEEADRTSSKKTKTQEISRPNSP---SEGEGESSDSRSVNDEGSSDPKDIDQDN 708
Query: 139 TISGPLIPPASPRLGNTSEAHGAAR-----TAPPRPNVPA---PPPPTPPPPPPPLPPPL 190
+ P IP SP+ N S++ +A+ PP P P P + PP P LP P
Sbjct: 709 RSTSPSIP--SPQ-DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG 765
Query: 191 PSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPP-------------------PPPPPP 231
P+ S P P G T P P P AP P PPP P
Sbjct: 766 PTPSATAVP---PQGSPTASQAPN-QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 821
Query: 232 PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPA 291
P PP P L+ A +P AP H PPL P G L+A P + P
Sbjct: 822 PHPPLQP----LTGSAGQPS-APSH---AQPPLHGQGPPGPHSLQAGP------LLQHPG 867
Query: 292 PPPP--LPPYAS-------CSPRASLP--APPLPGVNSS--SETPP---PLPP------- 328
PP P LPP AS SP A+ P + LP S+ S+ PP PLPP
Sbjct: 868 PPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 927
Query: 329 -KSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPA--------- 378
K P PQ QA PP G PF + L PPPA
Sbjct: 928 IKPPPTTPIPQLPAPQAHKHPPHLSGPSPF----------SMNANLPPPPALKPLSSLST 977
Query: 379 ---PPARSPTTELSSKSQQATAWTPTQQPG 405
P A P +L +SQ + +P Q PG
Sbjct: 978 HHPPSAHPPPLQLMPQSQPLPS-SPAQPPG 1006
Score = 85.9 bits (211), Expect = 8e-17
Identities = 115/411 (27%), Positives = 143/411 (34%), Gaps = 67/411 (16%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALL--ADIQQGTRL 59
P P PP P P P P P + PP + T+S P+ +A + IQQ L
Sbjct: 749 PAPSSAPPGTPQLPTP--GPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 806
Query: 60 RKVTQINDRSAPQIESSKGTNKEGG--GSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117
+ P G G + + PP G P G +
Sbjct: 807 HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ---------GPPGPHSL 857
Query: 118 AGGKTGQGPGSRAPSPRLPNKTISG--PLIPPASPRLGNTSEAHGAARTA-----PPRPN 170
G Q PG P LP + G PL + +TS A+++A PPR
Sbjct: 858 QAGPLLQHPGPPQPF-GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 916
Query: 171 VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP 230
P PP P P PPP TP+ P P + P ++ P P + PP
Sbjct: 917 ---PLPPAPLAMPHIKPPP-------TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP- 965
Query: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPPI--PPPLPLLPPCGYPGLKAEPASPAQDAQE 288
PP L P S LS H PP PPPL L+P L + PA P Q
Sbjct: 966 ---PPALKPLSSLS----------THHPPSAHPPPLQLMPQS--QPLPSSPAQPPGLTQS 1010
Query: 289 PPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPL-PPKSPSFQAPPQKAGAQALP- 346
PPPP + P PP PPP+ PP PS PP G A P
Sbjct: 1011 QNLPPPP-ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP 1069
Query: 347 --APPAPPGS--------QPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTE 387
A GS P +Q K A + P PP RSP+ E
Sbjct: 1070 CSGAAASGGSIAGGSSCPLPTVQIKEEALDDA---EEPESPPPPPRSPSPE 1117
Score = 48.1 bits (113), Expect = 2e-05
Identities = 75/299 (25%), Positives = 101/299 (33%), Gaps = 74/299 (24%)
Query: 5 PPPPPPL--------PPPPPPLGAPPPPPPSAPPVSTDTSSLRRAD----PKGRSALLAD 52
PP P L P PP P G PP P+ T ++ P +SAL +
Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQS- 909
Query: 53 IQQGTRLRKV---------------TQINDRSAPQIESSKGTNKEGGGSANTRGASTPPT 97
QQ R + + T I APQ + K G S + A+ PP
Sbjct: 910 -QQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ--AHKHPPHLSGPSPFSMNANLPPP 966
Query: 98 LGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSE 157
P L+P ++ T P + P +L ++ P P P L +
Sbjct: 967 ---------PALKP-----LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 1012
Query: 158 AHGAARTAPP--------------RPNVPAPPPPTPPP--PPPPLPPPLPSSS--PIKTP 199
+ PP P VP PPP PP P PP P +S P +
Sbjct: 1013 LPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 1072
Query: 200 LVSPPGPLTKGN---LPVVA--------PPVPCAPPPPPPPPPPTPPPLPPASVLSDKA 247
+ G + G+ LP V P +PPPPP P P P + S S A
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSA 1131
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 96.7 bits (239), Expect = 4e-20
Identities = 136/509 (26%), Positives = 176/509 (34%), Gaps = 101/509 (19%)
Query: 27 SAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR-KVTQINDRSAPQIESSKGTNKEGGG 85
SA V + SS +++ + R + +D ++ R K T+ + S P S
Sbjct: 632 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSR 691
Query: 86 SANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPL- 144
S N G+S P + P + + + Q +A P L T P
Sbjct: 692 SVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP 751
Query: 145 --IPPASPRL---GNTSEAHGA-------ARTAPPRPNVPAPPPPT----------PPPP 182
PP +P+L G T A A AP +P P P P P P
Sbjct: 752 SSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRP 811
Query: 183 PPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPP-----------PPP 231
P P PPP PS P PL G + + P A P PP P P P
Sbjct: 812 PSPHPPPHPSPHPPLQPLTGSAG---QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 868
Query: 232 PTPPPLPPASVLSDKAV--KPQLAPLHL---------------PPIPPPLPLLPPCGYPG 274
P P LPP + + P A H PP PLP P P
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP-LAMPH 927
Query: 275 LKAEPASPAQDAQEPPAP--PPPLPPYASCSPRASLPAPPLPGVNSSSET-------PPP 325
+K P +P P A PP L + S A+LP PP SS T PPP
Sbjct: 928 IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 987
Query: 326 L---PPKSPSFQAPPQKAG---AQALPAPPA--PP-------GSQPFLQKKRHGRPGAGG 370
L P P +P Q G +Q LP PPA PP PF Q P G
Sbjct: 988 LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ-----HPFVPG 1042
Query: 371 GKLNPPPAPPARSPTTELSSKSQQATAWTP---TQQPGGQLRNGSLHIIDDFESKFTFHS 427
G PPP P P+T +A P GG + GS + + K +
Sbjct: 1043 G---PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIK--EEA 1097
Query: 428 VEDFPPPDEYKPCQKIYPSKIPRSRTPGP 456
++D P+ P PRS +P P
Sbjct: 1098 LDDAEEPES--------PPPPPRSPSPEP 1118
Score = 87.0 bits (214), Expect = 3e-17
Identities = 121/450 (26%), Positives = 165/450 (36%), Gaps = 100/450 (22%)
Query: 21 PPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQIESSKGTN 80
P P P++ D S R P S D + T + ++ + ++ ++S+K
Sbjct: 592 PASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQR 651
Query: 81 KEGGGSANT--RGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNK 138
++ R +S ++ P G+ + + ++ GS P +
Sbjct: 652 EKVASDTEEADRTSSKKTKTQEISRPNSP---SEGEGESSDSRSVNDEGSSDPKDIDQDN 708
Query: 139 TISGPLIPPASPRLGNTSEAHGAAR-----TAPPRPNVPA---PPPPTPPPPPPPLPPPL 190
+ P IP SP+ N S++ +A+ PP P P P + PP P LP P
Sbjct: 709 RSTSPSIP--SPQ-DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG 765
Query: 191 PSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPP-------------------PPPPPP 231
P+ S P P G T P P P AP P PPP P
Sbjct: 766 PTPSATAVP---PQGSPTASQAPN-QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS 821
Query: 232 PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPA 291
P PP P L+ A +P AP H PPL P G L+A P + P
Sbjct: 822 PHPPLQP----LTGSAGQPS-APSH---AQPPLHGQGPPGPHSLQAGP------LLQHPG 867
Query: 292 PPPP--LPPYAS-------CSPRASLP--APPLPGVNSS--SETPP---PLPP------- 328
PP P LPP AS SP A+ P + LP S+ S+ PP PLPP
Sbjct: 868 PPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 927
Query: 329 -KSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPA--------- 378
K P PQ QA PP G PF + L PPPA
Sbjct: 928 IKPPPTTPIPQLPAPQAHKHPPHLSGPSPF----------SMNANLPPPPALKPLSSLST 977
Query: 379 ---PPARSPTTELSSKSQQATAWTPTQQPG 405
P A P +L +SQ + +P Q PG
Sbjct: 978 HHPPSAHPPPLQLMPQSQPLPS-SPAQPPG 1006
Score = 85.9 bits (211), Expect = 8e-17
Identities = 115/411 (27%), Positives = 143/411 (34%), Gaps = 67/411 (16%)
Query: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALL--ADIQQGTRL 59
P P PP P P P P P + PP + T+S P+ +A + IQQ L
Sbjct: 749 PAPSSAPPGTPQLPTP--GPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 806
Query: 60 RKVTQINDRSAPQIESSKGTNKEGG--GSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117
+ P G G + + PP G P G +
Sbjct: 807 HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ---------GPPGPHSL 857
Query: 118 AGGKTGQGPGSRAPSPRLPNKTISG--PLIPPASPRLGNTSEAHGAARTA-----PPRPN 170
G Q PG P LP + G PL + +TS A+++A PPR
Sbjct: 858 QAGPLLQHPGPPQPF-GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 916
Query: 171 VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP 230
P PP P P PPP TP+ P P + P ++ P P + PP
Sbjct: 917 ---PLPPAPLAMPHIKPPP-------TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPP- 965
Query: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPPI--PPPLPLLPPCGYPGLKAEPASPAQDAQE 288
PP L P S LS H PP PPPL L+P L + PA P Q
Sbjct: 966 ---PPALKPLSSLS----------THHPPSAHPPPLQLMPQS--QPLPSSPAQPPGLTQS 1010
Query: 289 PPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPL-PPKSPSFQAPPQKAGAQALP- 346
PPPP + P PP PPP+ PP PS PP G A P
Sbjct: 1011 QNLPPPP-ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP 1069
Query: 347 --APPAPPGS--------QPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTE 387
A GS P +Q K A + P PP RSP+ E
Sbjct: 1070 CSGAAASGGSIAGGSSCPLPTVQIKEEALDDA---EEPESPPPPPRSPSPE 1117
Score = 48.1 bits (113), Expect = 2e-05
Identities = 75/299 (25%), Positives = 101/299 (33%), Gaps = 74/299 (24%)
Query: 5 PPPPPPL--------PPPPPPLGAPPPPPPSAPPVSTDTSSLRRAD----PKGRSALLAD 52
PP P L P PP P G PP P+ T ++ P +SAL +
Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQS- 909
Query: 53 IQQGTRLRKV---------------TQINDRSAPQIESSKGTNKEGGGSANTRGASTPPT 97
QQ R + + T I APQ + K G S + A+ PP
Sbjct: 910 -QQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ--AHKHPPHLSGPSPFSMNANLPPP 966
Query: 98 LGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSE 157
P L+P ++ T P + P +L ++ P P P L +
Sbjct: 967 ---------PALKP-----LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 1012
Query: 158 AHGAARTAPP--------------RPNVPAPPPPTPPP--PPPPLPPPLPSSS--PIKTP 199
+ PP P VP PPP PP P PP P +S P +
Sbjct: 1013 LPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 1072
Query: 200 LVSPPGPLTKGN---LPVVA--------PPVPCAPPPPPPPPPPTPPPLPPASVLSDKA 247
+ G + G+ LP V P +PPPPP P P P + S S A
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSA 1131
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.135 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,956,612
Number of Sequences: 37866
Number of extensions: 3858882
Number of successful extensions: 206844
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2009
Number of HSP's successfully gapped in prelim test: 2249
Number of HSP's that attempted gapping in prelim test: 25804
Number of HSP's gapped (non-prelim): 62203
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.