Search of human proteins with 122937436

Search of human proteins with 122937436

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937436 tetratricopeptide repeat domain 39A isoform 2
[Homo sapiens]
         (578 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937436 tetratricopeptide repeat domain 39A isoform 2 [Homo...  1169   0.0  
gi|221307588 tetratricopeptide repeat domain 39A isoform 1 [Homo...  1134   0.0  
gi|22749191 tetratricopeptide repeat domain 39B [Homo sapiens]        615   e-176
gi|209862743 tetratricopeptide repeat domain 39C isoform 1 [Homo...   168   1e-41
gi|116256462 tetratricopeptide repeat domain 39C isoform 2 [Homo...   161   1e-39
gi|4557485 ceruloplasmin precursor [Homo sapiens]                      32   1.6  
gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo...    31   2.7  
gi|157502177 tetratricopeptide repeat domain 21A isoform 2 [Homo...    31   2.7  
gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]             31   3.6  
gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Ho...    31   3.6  
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    31   3.6  
gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [H...    31   3.6  
gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Ho...    31   3.6  
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    30   7.9  
gi|21735598 programmed cell death 4 isoform 2 [Homo sapiens]           30   7.9  
gi|21735596 programmed cell death 4 isoform 1 [Homo sapiens]           30   7.9  

>gi|122937436 tetratricopeptide repeat domain 39A isoform 2 [Homo
           sapiens]
          Length = 578

 Score = 1169 bits (3023), Expect = 0.0
 Identities = 578/578 (100%), Positives = 578/578 (100%)

Query: 1   MGQKGHKDSLYPCGGTPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLT 60
           MGQKGHKDSLYPCGGTPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLT
Sbjct: 1   MGQKGHKDSLYPCGGTPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLT 60

Query: 61  YATILEMQAMMTFDPQDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEE 120
           YATILEMQAMMTFDPQDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEE
Sbjct: 61  YATILEMQAMMTFDPQDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEE 120

Query: 121 EIHAEVCYAECLLQRAALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCKGEN 180
           EIHAEVCYAECLLQRAALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCKGEN
Sbjct: 121 EIHAEVCYAECLLQRAALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCKGEN 180

Query: 181 HPHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLC 240
           HPHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLC
Sbjct: 181 HPHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLC 240

Query: 241 VMLLLCYHTFLTFVLGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAI 300
           VMLLLCYHTFLTFVLGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAI
Sbjct: 241 VMLLLCYHTFLTFVLGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAI 300

Query: 301 RRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKA 360
           RRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKA
Sbjct: 301 RRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKA 360

Query: 361 AYLSMFGKEDHKPFGDDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPV 420
           AYLSMFGKEDHKPFGDDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPV
Sbjct: 361 AYLSMFGKEDHKPFGDDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPV 420

Query: 421 PALEMMYIWNGYAVIGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCL 480
           PALEMMYIWNGYAVIGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCL
Sbjct: 421 PALEMMYIWNGYAVIGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCL 480

Query: 481 KYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQN 540
           KYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQN
Sbjct: 481 KYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQN 540

Query: 541 YKNYSMESRTHFRIQAATLQAKSSLENSSRSMVSSVSL 578
           YKNYSMESRTHFRIQAATLQAKSSLENSSRSMVSSVSL
Sbjct: 541 YKNYSMESRTHFRIQAATLQAKSSLENSSRSMVSSVSL 578


>gi|221307588 tetratricopeptide repeat domain 39A isoform 1 [Homo
           sapiens]
          Length = 581

 Score = 1134 bits (2934), Expect = 0.0
 Identities = 563/563 (100%), Positives = 563/563 (100%)

Query: 16  TPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDP 75
           TPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDP
Sbjct: 19  TPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDP 78

Query: 76  QDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEEEIHAEVCYAECLLQR 135
           QDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEEEIHAEVCYAECLLQR
Sbjct: 79  QDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEEEIHAEVCYAECLLQR 138

Query: 136 AALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCKGENHPHFEGGVKLGVGAF 195
           AALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCKGENHPHFEGGVKLGVGAF
Sbjct: 139 AALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCKGENHPHFEGGVKLGVGAF 198

Query: 196 NLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHTFLTFVL 255
           NLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHTFLTFVL
Sbjct: 199 NLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHTFLTFVL 258

Query: 256 GTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAIRRFEECCEAQQHWKQ 315
           GTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAIRRFEECCEAQQHWKQ
Sbjct: 259 GTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAIRRFEECCEAQQHWKQ 318

Query: 316 FHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKAAYLSMFGKEDHKPFG 375
           FHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKAAYLSMFGKEDHKPFG
Sbjct: 319 FHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKAAYLSMFGKEDHKPFG 378

Query: 376 DDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPVPALEMMYIWNGYAVI 435
           DDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPVPALEMMYIWNGYAVI
Sbjct: 379 DDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPVPALEMMYIWNGYAVI 438

Query: 436 GKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRS 495
           GKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRS
Sbjct: 439 GKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRS 498

Query: 496 ISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQNYKNYSMESRTHFRIQ 555
           ISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQNYKNYSMESRTHFRIQ
Sbjct: 499 ISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQNYKNYSMESRTHFRIQ 558

Query: 556 AATLQAKSSLENSSRSMVSSVSL 578
           AATLQAKSSLENSSRSMVSSVSL
Sbjct: 559 AATLQAKSSLENSSRSMVSSVSL 581


>gi|22749191 tetratricopeptide repeat domain 39B [Homo sapiens]
          Length = 616

 Score =  615 bits (1586), Expect = e-176
 Identities = 297/541 (54%), Positives = 404/541 (74%), Gaps = 4/541 (0%)

Query: 21  LHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILL 80
           L   L++C  AL+LFL+N+F++AL  L+P  KESMYH+L Y+TI+ +QA++TF+ QDI  
Sbjct: 66  LKSGLEECAVALNLFLSNKFTDALELLRPWAKESMYHALGYSTIVVLQAVLTFEQQDIQN 125

Query: 81  AGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEEEIHAEVCYAECLLQRAALTF 140
             + MK+A   CQ++R+K +V +SFSSL++R +L Q +EEE+HAE+CYAECLLQ+AALTF
Sbjct: 126 GISAMKDALQTCQKYRKKYTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQKAALTF 185

Query: 141 LQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCK--GENHPHFEGGVKLGVGAFNLT 198
           +QDENM++FIKGG+K+R SYQ YKE  S++   Q  K   E    FEGGVKLG GAFNL 
Sbjct: 186 VQDENMINFIKGGLKIRTSYQIYKECLSILHEIQKNKLQQEFFYEFEGGVKLGSGAFNLM 245

Query: 199 LSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHTFLTFVLGTG 258
           LS+LP RI+RLLEF+GFSGN++ GLLQL EGASG S RS LC + +L +HT+++ +LGTG
Sbjct: 246 LSLLPARIIRLLEFIGFSGNRELGLLQLREGASGRSMRSALCCLTILAFHTYISLILGTG 305

Query: 259 NVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAIRRFEECCEAQQHWKQFHH 318
            VN+ EAE+LL P+L ++P G++ LF+  RIE++KGN++ A   F++C   Q+ WKQFHH
Sbjct: 306 EVNVAEAERLLAPFLQQFPNGSLVLFYHARIELLKGNLEEAQEVFQKCVSVQEEWKQFHH 365

Query: 319 MCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKAAYLSMFGKEDHKPFGDDE 378
           +CYWELMW   ++  W  +Y+Y+DLL KE+ WSKATY+++KAA LSM  +ED     ++ 
Sbjct: 366 LCYWELMWINVFQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEDVVATNENV 425

Query: 379 VELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSS--NPISLPVPALEMMYIWNGYAVIG 436
           V LFR V  LK +IAGKS+PTEKFA+RK+RRY +S   P+ L +PALEMMY+WNG++++ 
Sbjct: 426 VTLFRQVDSLKQRIAGKSIPTEKFAVRKARRYSASLPAPVKLILPALEMMYVWNGFSIVS 485

Query: 437 KQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRSI 496
           K+  L++ +L  + KAE  L+    N +SVDDECLVKLLKG CLK L R  +AE  +  +
Sbjct: 486 KRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGCCLKNLQRPLQAELCYNHV 545

Query: 497 SANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQNYKNYSMESRTHFRIQA 556
             +EK +KYDHYL+P  L ELA L   Q   ++AIK LE+A+ NYK+YS+ESR HFRIQA
Sbjct: 546 VESEKLLKYDHYLVPFTLFELASLYKSQGEIDKAIKFLETARNNYKDYSLESRLHFRIQA 605

Query: 557 A 557
           A
Sbjct: 606 A 606


>gi|209862743 tetratricopeptide repeat domain 39C isoform 1 [Homo
           sapiens]
          Length = 583

 Score =  168 bits (426), Expect = 1e-41
 Identities = 140/567 (24%), Positives = 258/567 (45%), Gaps = 65/567 (11%)

Query: 29  MTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEA 88
           +  +++ L N F E+    K     S   S   + +  + AMMTF+ + + LA + +K  
Sbjct: 34  LAGINMLLNNGFRESDQLFKQYRNHSPLMSFGASFVSFLNAMMTFEEEKMQLACDDLKTT 93

Query: 89  QMLCQRHRRK--SSVTDSFSSLVNRPTLGQFTEEEIHAEVCYAECLLQRAALTFLQDENM 146
           + LC+        ++ +     V+         + +  ++  A+C +  A L+F++ E +
Sbjct: 94  EKLCESEEAGVIETIKNKIKKNVDVRKSAPSMVDRLQRQIIIADCQVYLAVLSFVKQE-L 152

Query: 147 VSFIKGGIKVRNSYQTYKE--LDSLVQSSQYCK------------GENH----------- 181
            ++IKGG  +R +++ Y +  LD       Y K             +NH           
Sbjct: 153 SAYIKGGWILRKAWKIYNKCYLDINALQELYQKKLTEESLTSDAANDNHIVAEGVSEESL 212

Query: 182 PHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCV 241
              +G V  G G F+L +SM+P  +L+++  +GF G++  GL  L   +     ++ L  
Sbjct: 213 NRLKGAVSFGYGLFHLCISMVPPNLLKIINLLGFPGDRLQGLSSLMYASESKDMKAPLAT 272

Query: 242 MLLLCYHTFLT--FVL-GTGN-VNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNID 297
           + LL YHT +   F L G+ N   ++EA+++L      YP  ++F+FF GRI+ ++  I+
Sbjct: 273 LALLWYHTVVRPFFALDGSDNKAGLDEAKEILLKKEAAYPNSSLFMFFKGRIQRLECQIN 332

Query: 298 AAIRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIY 357
           +A+  F    E     ++  H+C +E+ WC   +  +K ++   + L  E+ WS+  Y Y
Sbjct: 333 SALTSFHTALELAVDQREIQHVCLYEIGWCSMIELNFKDAFDSFERLKNESRWSQCYYAY 392

Query: 358 MKAAYLSMFGKEDHKPFGDDEVE-LFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPI 416
           + A      G  D       EV+ LF+           K+   E+F+++K+ R+    P 
Sbjct: 393 LTAVCQGATGDVDGAQIVFKEVQKLFKR----------KNNQIEQFSVKKAERFRKQTPT 442

Query: 417 S--LPVPALEMMYIWNGYAVIGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLV-- 472
                + ++E++Y+W         P  +   L+ +++A           + VDD  +V  
Sbjct: 443 KALCVLASIEVLYLWKAL------PNCSFPNLQRMSQA----------CHEVDDSSVVGL 486

Query: 473 -KLLKGLCLKYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQDRN-EEA 530
             LL G   K LG  ++A + F+    +E   + + Y+ P A  EL  LL+++       
Sbjct: 487 KYLLLGAIHKCLGNSEDAVQYFQRAVKDELCRQNNLYVQPYACYELGCLLLDKPETVGRG 546

Query: 531 IKLLESAKQNYKNYSMESRTHFRIQAA 557
             LL  AK+++  Y  E+R H RI AA
Sbjct: 547 RALLLQAKEDFSGYDFENRLHVRIHAA 573


>gi|116256462 tetratricopeptide repeat domain 39C isoform 2 [Homo
           sapiens]
          Length = 522

 Score =  161 bits (408), Expect = 1e-39
 Identities = 133/529 (25%), Positives = 244/529 (46%), Gaps = 65/529 (12%)

Query: 67  MQAMMTFDPQDILLAGNMMKEAQMLCQRHRRK--SSVTDSFSSLVNRPTLGQFTEEEIHA 124
           + AMMTF+ + + LA + +K  + LC+        ++ +     V+         + +  
Sbjct: 11  LNAMMTFEEEKMQLACDDLKTTEKLCESEEAGVIETIKNKIKKNVDVRKSAPSMVDRLQR 70

Query: 125 EVCYAECLLQRAALTFLQDENMVSFIKGGIKVRNSYQTYKE--LDSLVQSSQYCK----- 177
           ++  A+C +  A L+F++ E + ++IKGG  +R +++ Y +  LD       Y K     
Sbjct: 71  QIIIADCQVYLAVLSFVKQE-LSAYIKGGWILRKAWKIYNKCYLDINALQELYQKKLTEE 129

Query: 178 -------GENH-----------PHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNK 219
                   +NH              +G V  G G F+L +SM+P  +L+++  +GF G++
Sbjct: 130 SLTSDAANDNHIVAEGVSEESLNRLKGAVSFGYGLFHLCISMVPPNLLKIINLLGFPGDR 189

Query: 220 DYGLLQLEEGASGHSFRSVLCVMLLLCYHTFLT--FVL-GTGN-VNIEEAEKLLKPYLNR 275
             GL  L   +     ++ L  + LL YHT +   F L G+ N   ++EA+++L      
Sbjct: 190 LQGLSSLMYASESKDMKAPLATLALLWYHTVVRPFFALDGSDNKAGLDEAKEILLKKEAA 249

Query: 276 YPKGAIFLFFAGRIEVIKGNIDAAIRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWK 335
           YP  ++F+FF GRI+ ++  I++A+  F    E     ++  H+C +E+ WC   +  +K
Sbjct: 250 YPNSSLFMFFKGRIQRLECQINSALTSFHTALELAVDQREIQHVCLYEIGWCSMIELNFK 309

Query: 336 MSYFYADLLSKENCWSKATYIYMKAAYLSMFGKEDHKPFGDDEVE-LFRAVPGLKLKIAG 394
            ++   + L  E+ WS+  Y Y+ A      G  D       EV+ LF+           
Sbjct: 310 DAFDSFERLKNESRWSQCYYAYLTAVCQGATGDVDGAQIVFKEVQKLFKR---------- 359

Query: 395 KSLPTEKFAIRKSRRYFSSNPIS--LPVPALEMMYIWNGYAVIGKQPKLTDGILEIITKA 452
           K+   E+F+++K+ R+    P      + ++E++Y+W         P  +   L+ +++A
Sbjct: 360 KNNQIEQFSVKKAERFRKQTPTKALCVLASIEVLYLWKAL------PNCSFPNLQRMSQA 413

Query: 453 EEMLEKGPENEYSVDDECLV---KLLKGLCLKYLGRVQEAEENFRSISANEKKIKYDHYL 509
                      + VDD  +V    LL G   K LG  ++A + F+    +E   + + Y+
Sbjct: 414 ----------CHEVDDSSVVGLKYLLLGAIHKCLGNSEDAVQYFQRAVKDELCRQNNLYV 463

Query: 510 IPNALLELALLLMEQDRN-EEAIKLLESAKQNYKNYSMESRTHFRIQAA 557
            P A  EL  LL+++         LL  AK+++  Y  E+R H RI AA
Sbjct: 464 QPYACYELGCLLLDKPETVGRGRALLLQAKEDFSGYDFENRLHVRIHAA 512


>gi|4557485 ceruloplasmin precursor [Homo sapiens]
          Length = 1065

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 27/126 (21%), Positives = 57/126 (45%), Gaps = 20/126 (15%)

Query: 310 QQHW-KQFHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATY---IYMKAA--YL 363
           Q+ W K+ HH+    +   F  KG++ +   Y  ++ ++  ++ +T+   +  KA   +L
Sbjct: 748 QREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYRQ--YTDSTFRVPVERKAEEEHL 805

Query: 364 SMFGKEDHKPFGDDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPVPAL 423
            + G + H   GD            K+KI  K++ T  ++I        S+ ++  +P  
Sbjct: 806 GILGPQLHADVGD------------KVKIIFKNMATRPYSIHAHGVQTESSTVTPTLPGE 853

Query: 424 EMMYIW 429
            + Y+W
Sbjct: 854 TLTYVW 859


>gi|157502179 tetratricopeptide repeat domain 21A isoform 1 [Homo
            sapiens]
          Length = 1321

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 16/65 (24%), Positives = 33/65 (50%), Gaps = 1/65 (1%)

Query: 481  KYLGRVQEAEENFRSISANEKKI-KYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQ 539
            +Y+G + E E++++    N K   KY H+  P    +LA   ++  +  EAI++     +
Sbjct: 1240 EYMGFIMEKEQSYKDAVTNYKLAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLR 1299

Query: 540  NYKNY 544
             + +Y
Sbjct: 1300 EHPDY 1304


>gi|157502177 tetratricopeptide repeat domain 21A isoform 2 [Homo
            sapiens]
          Length = 1320

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 16/65 (24%), Positives = 33/65 (50%), Gaps = 1/65 (1%)

Query: 481  KYLGRVQEAEENFRSISANEKKI-KYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQ 539
            +Y+G + E E++++    N K   KY H+  P    +LA   ++  +  EAI++     +
Sbjct: 1239 EYMGFIMEKEQSYKDAVTNYKLAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLR 1298

Query: 540  NYKNY 544
             + +Y
Sbjct: 1299 EHPDY 1303


>gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]
          Length = 1133

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 13/92 (14%)

Query: 446 LEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRSISANEKKIKY 505
           LE+I  A     K  E  Y   +E L +  + L  +YL + QEAE+    ++A  ++   
Sbjct: 621 LELIESAHRSRIKVLETSYQQREERLRRENEELSARYLSQCQEAEQARAELTAQHQR--- 677

Query: 506 DHYLIPNALLELALLLMEQDRNEEAIKLLESA 537
                      LA +  E+D+  E ++ L+ A
Sbjct: 678 ----------RLAAIAQEKDQEMERLRELQRA 699


>gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Homo
           sapiens]
          Length = 864

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 17/44 (38%), Positives = 27/44 (61%)

Query: 453 EEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRSI 496
           +E LE     E  + D+ LV+ +KG  L  LGR++EA E F+++
Sbjct: 207 QESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNL 250


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 6/92 (6%)

Query: 481  KYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQN 540
            K   R+QEAEE+  +++A    ++     + N   E+  L+++ +R+  A   L+  ++N
Sbjct: 1395 KLAQRLQEAEEHVEAVNAKCASLEKTKQRLQN---EVEDLMLDVERSNAACAALDKKQRN 1451

Query: 541  YKNYSMESRTHFRIQAATLQAKSSLENSSRSM 572
            +     E +  +    A L+A    +  SRS+
Sbjct: 1452 FDKVLSEWKQKYEETQAELEAS---QKESRSL 1480


>gi|160707985 NMDA receptor regulated 1-like protein isoform 3 [Homo
           sapiens]
          Length = 429

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 17/44 (38%), Positives = 27/44 (61%)

Query: 453 EEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRSI 496
           +E LE     E  + D+ LV+ +KG  L  LGR++EA E F+++
Sbjct: 207 QESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNL 250


>gi|33356130 NMDA receptor regulated 1-like protein isoform 2 [Homo
           sapiens]
          Length = 311

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 17/44 (38%), Positives = 27/44 (61%)

Query: 453 EEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRSI 496
           +E LE     E  + D+ LV+ +KG  L  LGR++EA E F+++
Sbjct: 207 QESLEHIEMYEKQICDKLLVEEIKGEILLKLGRLKEASEVFKNL 250


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 20/90 (22%), Positives = 45/90 (50%), Gaps = 9/90 (10%)

Query: 481  KYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQN 540
            K   R+QEAEE   +++A    ++   + + N   E+  L+++ +R+  A   L+  ++N
Sbjct: 1392 KLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN---EIEDLMVDVERSNAAAAALDKKQRN 1448

Query: 541  YKNYSMESRTHFRIQAATLQAKSSLENSSR 570
            +     E +  +       +++S LE+S +
Sbjct: 1449 FDKILAEWKQKYE------ESQSELESSQK 1472


>gi|21735598 programmed cell death 4 isoform 2 [Homo sapiens]
          Length = 458

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 18/59 (30%), Positives = 26/59 (44%)

Query: 7   KDSLYPCGGTPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATIL 65
           KDS++  GG  +S  H   +  M   +  L+   SEA   LK       +H L Y  I+
Sbjct: 300 KDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAII 358


>gi|21735596 programmed cell death 4 isoform 1 [Homo sapiens]
          Length = 469

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 18/59 (30%), Positives = 26/59 (44%)

Query: 7   KDSLYPCGGTPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATIL 65
           KDS++  GG  +S  H   +  M   +  L+   SEA   LK       +H L Y  I+
Sbjct: 311 KDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFHHELVYEAII 369


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,700,639
Number of Sequences: 37866
Number of extensions: 888728
Number of successful extensions: 2132
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2110
Number of HSP's gapped (non-prelim): 20
length of query: 578
length of database: 18,247,518
effective HSP length: 108
effective length of query: 470
effective length of database: 14,157,990
effective search space: 6654255300
effective search space used: 6654255300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.