Search of human proteins with 31377644

Search of human proteins with 31377644

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31377644 ATPase family, AAA domain containing 1 [Homo
sapiens]
         (361 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens]     717   0.0  
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]               192   3e-49
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]               192   3e-49
gi|40806170 spastin isoform 2 [Homo sapiens]                          192   4e-49
gi|11875211 spastin isoform 1 [Homo sapiens]                          192   4e-49
gi|31742536 fidgetin-like 1 [Homo sapiens]                            191   7e-49
gi|112789543 fidgetin-like 1 [Homo sapiens]                           191   7e-49
gi|5901990 katanin p60 subunit A 1 [Homo sapiens]                     189   3e-48
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]         176   3e-44
gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]              171   7e-43
gi|6005942 valosin-containing protein [Homo sapiens]                  161   7e-40
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]           160   1e-39
gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]          160   2e-39
gi|157671927 spermatogenesis associated 5 [Homo sapiens]              154   2e-37
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                 147   1e-35
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                 147   1e-35
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]            146   3e-35
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]            145   7e-35
gi|64084766 fidgetin [Homo sapiens]                                   145   7e-35
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]     144   2e-34
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]   143   3e-34
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]       139   4e-33
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ...   137   1e-32
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi...   137   1e-32
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]   137   1e-32
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]            136   3e-32
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]             120   1e-27
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]            118   7e-27
gi|4505725 peroxin1 [Homo sapiens]                                    117   2e-26
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]           115   5e-26

>gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens]
          Length = 361

 Score =  717 bits (1852), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDPTRKQKVEAQKQAEKLMK 60
           MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDPTRKQKVEAQKQAEKLMK
Sbjct: 1   MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDPTRKQKVEAQKQAEKLMK 60

Query: 61  QIGVKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENS 120
           QIGVKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENS
Sbjct: 61  QIGVKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENS 120

Query: 121 RLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSL 180
           RLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSL
Sbjct: 121 RLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSL 180

Query: 181 AIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRP 240
           AIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRP
Sbjct: 181 AIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRP 240

Query: 241 QDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLK 300
           QDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLK
Sbjct: 241 QDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLK 300

Query: 301 EMCRDAALLCVREYVNSTSEESHDEDEIRPVQQQDLHRAIEKMKKSKDAAFQNVLTHVCL 360
           EMCRDAALLCVREYVNSTSEESHDEDEIRPVQQQDLHRAIEKMKKSKDAAFQNVLTHVCL
Sbjct: 301 EMCRDAALLCVREYVNSTSEESHDEDEIRPVQQQDLHRAIEKMKKSKDAAFQNVLTHVCL 360

Query: 361 D 361
           D
Sbjct: 361 D 361


>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  192 bits (489), Expect = 3e-49
 Identities = 109/276 (39%), Positives = 164/276 (59%), Gaps = 12/276 (4%)

Query: 85  NMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAK 144
           N  + W DIA L++    L++ V+LP+     F+  R  +P KGVL+ GPPG GKT++AK
Sbjct: 202 NPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIR--RPWKGVLMVGPPGTGKTMLAK 259

Query: 145 ATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSS 204
           A A E G  F N+  STLT K+ GES+KL   +F +A    P+ IFIDEIDS    R +S
Sbjct: 260 AVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTS 319

Query: 205 D-HEATAMMKAQFMSLWDGL-----DTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHIN 258
           D HEA+  +K++ +   DG+     + D S  V+V+ ATN P D+D A+ RR+  R +I 
Sbjct: 320 DEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIP 379

Query: 259 QPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST 318
            P  K R  +LK+ L+   +D  + L ++A++ +G+SG+D+  +CRDA+L+ +R  +N  
Sbjct: 380 LPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMRRRINGL 439

Query: 319 SEES----HDEDEIRPVQQQDLHRAIEKMKKSKDAA 350
           S E       E+   PV + D   A++K+ KS  AA
Sbjct: 440 SPEEIRALSKEELQMPVTKGDFELALKKIAKSVSAA 475


>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  192 bits (489), Expect = 3e-49
 Identities = 109/276 (39%), Positives = 164/276 (59%), Gaps = 12/276 (4%)

Query: 85  NMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAK 144
           N  + W DIA L++    L++ V+LP+     F+  R  +P KGVL+ GPPG GKT++AK
Sbjct: 202 NPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIR--RPWKGVLMVGPPGTGKTMLAK 259

Query: 145 ATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSS 204
           A A E G  F N+  STLT K+ GES+KL   +F +A    P+ IFIDEIDS    R +S
Sbjct: 260 AVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTS 319

Query: 205 D-HEATAMMKAQFMSLWDGL-----DTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHIN 258
           D HEA+  +K++ +   DG+     + D S  V+V+ ATN P D+D A+ RR+  R +I 
Sbjct: 320 DEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIP 379

Query: 259 QPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST 318
            P  K R  +LK+ L+   +D  + L ++A++ +G+SG+D+  +CRDA+L+ +R  +N  
Sbjct: 380 LPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMRRRINGL 439

Query: 319 SEES----HDEDEIRPVQQQDLHRAIEKMKKSKDAA 350
           S E       E+   PV + D   A++K+ KS  AA
Sbjct: 440 SPEEIRALSKEELQMPVTKGDFELALKKIAKSVSAA 475


>gi|40806170 spastin isoform 2 [Homo sapiens]
          Length = 584

 Score =  192 bits (488), Expect = 4e-49
 Identities = 106/260 (40%), Positives = 166/260 (63%), Gaps = 4/260 (1%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           V + DIAG D     L++ VILP  +  LF   R   P +G+LL+GPPG GKT++AKA A
Sbjct: 307 VKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRA--PARGLLLFGPPGNGKTMLAKAVA 364

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHE 207
            E+   F N+  ++LT K+ GE +KL  A+F++A +LQPSIIFIDE+DS L  R   +H+
Sbjct: 365 AESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHD 424

Query: 208 ATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREA 267
           A+  +K +F+  +DG+ +    +V+VMGATNRPQ+LD A++RR   R +++ P  + R  
Sbjct: 425 ASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLL 484

Query: 268 ILK-LILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDED 326
           +LK L+ K  +     +L ++A+ TDG+SGSDL  + +DAAL  +RE +     ++    
Sbjct: 485 LLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRE-LKPEQVKNMSAS 543

Query: 327 EIRPVQQQDLHRAIEKMKKS 346
           E+R ++  D   +++K+K+S
Sbjct: 544 EMRNIRLSDFTESLKKIKRS 563


>gi|11875211 spastin isoform 1 [Homo sapiens]
          Length = 616

 Score =  192 bits (488), Expect = 4e-49
 Identities = 106/260 (40%), Positives = 166/260 (63%), Gaps = 4/260 (1%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           V + DIAG D     L++ VILP  +  LF   R   P +G+LL+GPPG GKT++AKA A
Sbjct: 339 VKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRA--PARGLLLFGPPGNGKTMLAKAVA 396

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHE 207
            E+   F N+  ++LT K+ GE +KL  A+F++A +LQPSIIFIDE+DS L  R   +H+
Sbjct: 397 AESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHD 456

Query: 208 ATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREA 267
           A+  +K +F+  +DG+ +    +V+VMGATNRPQ+LD A++RR   R +++ P  + R  
Sbjct: 457 ASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLL 516

Query: 268 ILK-LILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDED 326
           +LK L+ K  +     +L ++A+ TDG+SGSDL  + +DAAL  +RE +     ++    
Sbjct: 517 LLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRE-LKPEQVKNMSAS 575

Query: 327 EIRPVQQQDLHRAIEKMKKS 346
           E+R ++  D   +++K+K+S
Sbjct: 576 EMRNIRLSDFTESLKKIKRS 595


>gi|31742536 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score =  191 bits (486), Expect = 7e-49
 Identities = 95/260 (36%), Positives = 159/260 (61%), Gaps = 4/260 (1%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           V W DIAG++     +K+ V+ P+ +  +F   R   PPKG+LL+GPPG GKTLI K  A
Sbjct: 398 VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR--GPPKGILLFGPPGTGKTLIGKCIA 455

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHE 207
            ++G  F ++  S+LT KW GE +K+  A+F++A   QP++IFIDEIDS L  R   +HE
Sbjct: 456 SQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHE 515

Query: 208 ATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQP-ALKQRE 266
           ++  +K +F+   DG  T    +++V+GATNRPQ++D A  RR+  R +I  P A  +++
Sbjct: 516 SSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQ 575

Query: 267 AILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDED 326
            ++ L+ K +      ++ ++ Q++D FSG+D+ ++CR+A+L  +R  + +    +   D
Sbjct: 576 IVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRS-LQTADIATITPD 634

Query: 327 EIRPVQQQDLHRAIEKMKKS 346
           ++RP+   D   A   ++ S
Sbjct: 635 QVRPIAYIDFENAFRTVRPS 654


>gi|112789543 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score =  191 bits (486), Expect = 7e-49
 Identities = 95/260 (36%), Positives = 159/260 (61%), Gaps = 4/260 (1%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           V W DIAG++     +K+ V+ P+ +  +F   R   PPKG+LL+GPPG GKTLI K  A
Sbjct: 398 VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR--GPPKGILLFGPPGTGKTLIGKCIA 455

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHE 207
            ++G  F ++  S+LT KW GE +K+  A+F++A   QP++IFIDEIDS L  R   +HE
Sbjct: 456 SQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHE 515

Query: 208 ATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQP-ALKQRE 266
           ++  +K +F+   DG  T    +++V+GATNRPQ++D A  RR+  R +I  P A  +++
Sbjct: 516 SSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQ 575

Query: 267 AILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDED 326
            ++ L+ K +      ++ ++ Q++D FSG+D+ ++CR+A+L  +R  + +    +   D
Sbjct: 576 IVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRS-LQTADIATITPD 634

Query: 327 EIRPVQQQDLHRAIEKMKKS 346
           ++RP+   D   A   ++ S
Sbjct: 635 QVRPIAYIDFENAFRTVRPS 654


>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
          Length = 491

 Score =  189 bits (481), Expect = 3e-48
 Identities = 109/276 (39%), Positives = 161/276 (58%), Gaps = 12/276 (4%)

Query: 85  NMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAK 144
           N +V W DIA L +    LK+ V+LP+     F+  R  +P KGVL+ GPPG GKTL+AK
Sbjct: 203 NPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIR--RPWKGVLMVGPPGTGKTLLAK 260

Query: 145 ATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNR-SS 203
           A A E    F N+  STLT K+ GES+KL   +F +A    P+ IFIDEIDS    R +S
Sbjct: 261 AVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTS 320

Query: 204 SDHEATAMMKAQFMSLWDGL-----DTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHIN 258
            +HEA+  +KA+ +   DG+     + D S  V+V+ ATN P D+D A+ RR+  R +I 
Sbjct: 321 EEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIP 380

Query: 259 QPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST 318
            P+ K RE +L++ L+   +   VDL  +A+  +G+SG+D+  +CRDA+L+ +R  +   
Sbjct: 381 LPSAKGREELLRISLRELELADDVDLASIAENMEGYSGADITNVCRDASLMAMRRRIEGL 440

Query: 319 SEES----HDEDEIRPVQQQDLHRAIEKMKKSKDAA 350
           + E       E+   P   +D   A++K+ KS  AA
Sbjct: 441 TPEEIRNLSKEEMHMPTTMEDFEMALKKVSKSVSAA 476


>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
          Length = 444

 Score =  176 bits (446), Expect = 3e-44
 Identities = 103/234 (44%), Positives = 143/234 (61%), Gaps = 5/234 (2%)

Query: 87  HVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKAT 146
           +V WSD+AGL+     LK+ VILPIK  HLF   R   P +G+LL+GPPG GK+ +AKA 
Sbjct: 130 NVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRT--PWRGILLFGPPGTGKSYLAKAV 187

Query: 147 AKEAG-CRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSD 205
           A EA    F ++  S L  KW GES+KL   +F LA + +PSIIFIDEIDS   +RS ++
Sbjct: 188 ATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENE 247

Query: 206 HEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQR 265
            EA   +K +F+    G+  D+   ++V+GATN P  LDSAI RR   R +I  P    R
Sbjct: 248 SEAARRIKTEFLVQMQGVGVDND-GILVLGATNIPWVLDSAIRRRFEKRIYIPLPEPHAR 306

Query: 266 EAILKLIL-KNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST 318
            A+ KL L   +N     D  E+ ++TDG+SG+D+  + RDA +  VR+  ++T
Sbjct: 307 AAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQPVRKVQSAT 360


>gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]
          Length = 466

 Score =  171 bits (434), Expect = 7e-43
 Identities = 102/282 (36%), Positives = 159/282 (56%), Gaps = 22/282 (7%)

Query: 85  NMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAK 144
           N ++ W+DI GLD     +K+ V+ PI+   LF    +L P KG+LLYGPPG GKTL+AK
Sbjct: 176 NPNIKWNDIIGLDAAKQLVKEAVVYPIRYPQLFTG--ILSPWKGLLLYGPPGTGKTLLAK 233

Query: 145 ATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNR--- 201
           A A E    F N+  ST+  KW G+S+KL   +F LA    PS IF+DE++S +  R   
Sbjct: 234 AVATECKTTFFNISASTIVSKWRGDSEKLVRVLFELARYHAPSTIFLDELESVMSQRGTA 293

Query: 202 SSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPA 261
           S  +HE +  MK + +   DGL       V V+ A+N P +LD A++RR+  R  ++ P+
Sbjct: 294 SGGEHEGSLRMKTELLVQMDGLARSEDL-VFVLAASNLPWELDCAMLRRLEKRILVDLPS 352

Query: 262 LKQREAI----LKLILKNENVDRHVDL--LEVAQETDGFSGSDLKEMCRDAALLCVREYV 315
            + R+A+    L  + K+  ++ H +L    ++QET+G+SGSD+K +CR+AA+  VR+  
Sbjct: 353 REARQAMIYHWLPPVSKSRALELHTELEYSVLSQETEGYSGSDIKLVCREAAMRPVRKIF 412

Query: 316 NSTSEESHDEDEIRPVQQQDLHRAIEKMKKSKDAAFQNVLTH 357
           ++      +  ++  +Q          +     A F +VLTH
Sbjct: 413 DALENHQSESSDLPRIQ----------LDIVTTADFLDVLTH 444


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score =  161 bits (408), Expect = 7e-40
 Identities = 98/276 (35%), Positives = 151/276 (54%), Gaps = 20/276 (7%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           VTW DI GL+DV  +L++ V  P++    F    +  P KGVL YGPPGCGKTL+AKA A
Sbjct: 474 VTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMT-PSKGVLFYGPPGCGKTLLAKAIA 532

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHE 207
            E    FI+++   L   W+GES+     +F  A +  P ++F DE+DS  + R  +  +
Sbjct: 533 NECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGD 592

Query: 208 ---ATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPAL 262
              A   +  Q ++  DG+ T  +  V ++GATNRP  +D AI+R  R+    +I  P  
Sbjct: 593 GGGAADRVINQILTEMDGMSTKKN--VFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDE 650

Query: 263 KQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYV------- 315
           K R AILK  L+   V + VDL  +A+ T+GFSG+DL E+C+ A  L +RE +       
Sbjct: 651 KSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRE 710

Query: 316 -----NSTSEESHDEDEIRPVQQQDLHRAIEKMKKS 346
                N ++ E  ++D +  +++     A+   ++S
Sbjct: 711 RERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRS 746



 Score =  145 bits (365), Expect = 7e-35
 Identities = 91/241 (37%), Positives = 127/241 (52%), Gaps = 5/241 (2%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           V + DI G    +  +K+ V LP++   LF+   + +PP+G+LLYGPPG GKTLIA+A A
Sbjct: 201 VGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGV-KPPRGILLYGPPGTGKTLIARAVA 259

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHE 207
            E G  F  +    +  K  GES+      F  A K  P+IIFIDE+D+    R  +  E
Sbjct: 260 NETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGE 319

Query: 208 ATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQR 265
               + +Q ++L DGL       VIVM ATNRP  +D A+ R  R      I  P    R
Sbjct: 320 VERRIVSQLLTLMDGL--KQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGR 377

Query: 266 EAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDE 325
             IL++  KN  +   VDL +VA ET G  G+DL  +C +AAL  +R+ ++    E    
Sbjct: 378 LEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETI 437

Query: 326 D 326
           D
Sbjct: 438 D 438


>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
          Length = 403

 Score =  160 bits (406), Expect = 1e-39
 Identities = 114/329 (34%), Positives = 178/329 (54%), Gaps = 34/329 (10%)

Query: 35  KWMVDAIDPTRKQKVEAQKQAEKLMKQIGVKNVKLSEYEMSIAAHL---VDPL--NM--- 86
           K++V A +  R   V  ++Q +K   + G + V L    ++I  +L   VDPL  NM   
Sbjct: 82  KFIVKATNGPR-YVVGCRRQLDKSKLKPGTR-VALDMTTLTIMRYLPREVDPLVYNMSHE 139

Query: 87  ---HVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIA 143
              +V++S+I GL + I +L++ + LP+    LF+   ++ PPKG LLYGPPG GKTL+A
Sbjct: 140 DPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGII-PPKGCLLYGPPGTGKTLLA 198

Query: 144 KATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSS 203
           +A A +  C F+ +  S++ DK+ GES +L   +F+ A   QP IIF+DEID+    R S
Sbjct: 199 RAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFS 258

Query: 204 SDHEATAMMKAQFMSL---WDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHIN 258
               A   ++   M L    DG DT H  ++I+  ATNRP  LD A++R  R+  + HI+
Sbjct: 259 EGTSADREIQRTLMELLNQMDGFDTLHRVKMIM--ATNRPDTLDPALLRPGRLDRKIHID 316

Query: 259 QPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST 318
            P  + R  ILK+          +D   + + +DGF+G+DL+ +C +A +  +R      
Sbjct: 317 LPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIR------ 370

Query: 319 SEESHDEDEIRPVQQQDLHRAIEKMKKSK 347
               HD      V Q+D  +A+ K+  SK
Sbjct: 371 --ADHDF-----VVQEDFMKAVRKVADSK 392


>gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]
          Length = 437

 Score =  160 bits (405), Expect = 2e-39
 Identities = 93/234 (39%), Positives = 143/234 (61%), Gaps = 5/234 (2%)

Query: 87  HVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKAT 146
           ++ W+D+AGL+     LK+ VILPIK  HLF   R   P +G+LL+GPPG GK+ +AKA 
Sbjct: 123 NIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRT--PWRGILLFGPPGTGKSYLAKAV 180

Query: 147 AKEAG-CRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSD 205
           A EA    F ++  S L  KW GES+KL   +F LA + +PSIIFIDE+DS   +R+ ++
Sbjct: 181 ATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENE 240

Query: 206 HEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQR 265
            EA   +K +F+    G+  ++    +V+GATN P  LDSAI RR   R +I  P    R
Sbjct: 241 SEAARRIKTEFLVQMQGVGNNND-GTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAAR 299

Query: 266 EAILKLILKNENVD-RHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNST 318
             + +L L +   +    ++ E+A++T+G+SG+D+  + RD+ +  VR+  ++T
Sbjct: 300 AQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSAT 353


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score =  154 bits (388), Expect = 2e-37
 Identities = 90/235 (38%), Positives = 133/235 (56%), Gaps = 7/235 (2%)

Query: 87  HVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKAT 146
           +V+WSDI GL+ +   L+  V  P+K    F    + QPPKGVLLYGPPGC KT+IAKA 
Sbjct: 623 NVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGI-QPPKGVLLYGPPGCSKTMIAKAL 681

Query: 147 AKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSS-- 204
           A E+G  F+ ++   L +K+ GES++     F  A  + PSIIF DE+D+    R SS  
Sbjct: 682 ANESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIFFDELDALAVERGSSLG 741

Query: 205 DHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPAL 262
                  + AQ ++  DG+  +    V ++ ATNRP  +D A+MR  R+    ++  P  
Sbjct: 742 AGNVADRVLAQLLTEMDGI--EQLKDVTILAATNRPDRIDKALMRPGRIDRIIYVPLPDA 799

Query: 263 KQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNS 317
             R  I KL   +  V   VDL E+  +TD +SG+++  +CR+AALL + E + +
Sbjct: 800 ATRREIFKLQFHSMPVSNEVDLDELILQTDAYSGAEIVAVCREAALLALEEDIQA 854



 Score =  144 bits (364), Expect = 9e-35
 Identities = 85/229 (37%), Positives = 132/229 (57%), Gaps = 5/229 (2%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           VT+  I GL   +  +++ + LP+K+  LF+ S  +  P+GVLLYGPPG GKT+IA+A A
Sbjct: 350 VTYDMIGGLSSQLKAIREIIELPLKQPELFK-SYGIPAPRGVLLYGPPGTGKTMIARAVA 408

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHE 207
            E G     +    +  K+YGE++     +F+ A    PSIIFIDE+D+    R  + +E
Sbjct: 409 NEVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKREGAQNE 468

Query: 208 ATAMMKAQFMSLWDGLDTDHS-CQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQ 264
               + A  ++L DG+ ++ S  QV+V+GATNRP  LD+A+ R  R      I  P  + 
Sbjct: 469 VEKRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNAQD 528

Query: 265 REAIL-KLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVR 312
           R  IL KL+ +  ++    +LL++A    G+ G+DLK +C +A L  +R
Sbjct: 529 RLDILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALR 577


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score =  147 bits (372), Expect = 1e-35
 Identities = 91/267 (34%), Positives = 150/267 (56%), Gaps = 12/267 (4%)

Query: 87  HVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKAT 146
           +VTW+DI  L+D+  +L   ++ P++    F+   L+ P  GVLL GPPGCGKTL+AKA 
Sbjct: 471 NVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPA-GVLLAGPPGCGKTLLAKAV 529

Query: 147 AKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDH 206
           A E+G  FI+++   L + + GES++    VF  A    P +IF DE+D+    RS  + 
Sbjct: 530 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 589

Query: 207 EATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQ 264
            A+  +  Q ++  DGL+     QV +M ATNRP  +D AI+R  R+     +  P    
Sbjct: 590 GASVRVVNQLLTEMDGLEARQ--QVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPAD 647

Query: 265 REAILKLILKNEN---VDRHVDLLEVAQE--TDGFSGSDLKEMCRDAALLCVREYVNSTS 319
           R AILK I KN     +D  V+L  +A +   D ++G+DL  + R+A++  +R+ + +  
Sbjct: 648 RLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEM-ARQ 706

Query: 320 EESHDEDEIRPVQQQDLHRAIEKMKKS 346
           +  +++ E++ V  +    A +K++ S
Sbjct: 707 KSGNEKGELK-VSHKHFEEAFKKVRSS 732



 Score =  124 bits (312), Expect = 1e-28
 Identities = 87/287 (30%), Positives = 138/287 (48%), Gaps = 16/287 (5%)

Query: 46  KQKVEAQKQAEKLMKQIGVKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKD 105
           K+K E  ++ +  ++ +  K  K    E  I+         +V + D+ G D     LK+
Sbjct: 123 KRKKEDLQEVDGEIEAVLQKKAKARGLEFQIS---------NVKFEDVGGND---MTLKE 170

Query: 106 TVILPIKKKHLFENSRL-LQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTD 164
              + I  +H      L + PP+GVLL+GPPGCGKTL+A A A E     + +    +  
Sbjct: 171 VCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGELDLPILKVAAPEIVS 230

Query: 165 KWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGL- 223
              GES++    +F  A+   P IIFIDEID+    R  +  +    + AQ ++  D L 
Sbjct: 231 GVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKDMERRIVAQLLTCMDDLN 290

Query: 224 DTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQREAILKLILKNENVDRH 281
           +   + +V+V+GATNRP  LD A+ R  R      +  P    RE IL+ + +   + + 
Sbjct: 291 NVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRERILQTLCRKLRLPQA 350

Query: 282 VDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEI 328
            D   +A  T GF G+DL  +CR+AA+  V   +    E+     E+
Sbjct: 351 FDFCHLAHLTPGFVGADLMALCREAAMCAVNRVLMKLQEQQKKNPEM 397


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score =  147 bits (372), Expect = 1e-35
 Identities = 91/267 (34%), Positives = 150/267 (56%), Gaps = 12/267 (4%)

Query: 87  HVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKAT 146
           +VTW+DI  L+D+  +L   ++ P++    F+   L+ P  GVLL GPPGCGKTL+AKA 
Sbjct: 577 NVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPA-GVLLAGPPGCGKTLLAKAV 635

Query: 147 AKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDH 206
           A E+G  FI+++   L + + GES++    VF  A    P +IF DE+D+    RS  + 
Sbjct: 636 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 695

Query: 207 EATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQ 264
            A+  +  Q ++  DGL+     QV +M ATNRP  +D AI+R  R+     +  P    
Sbjct: 696 GASVRVVNQLLTEMDGLEARQ--QVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPAD 753

Query: 265 REAILKLILKNEN---VDRHVDLLEVAQE--TDGFSGSDLKEMCRDAALLCVREYVNSTS 319
           R AILK I KN     +D  V+L  +A +   D ++G+DL  + R+A++  +R+ + +  
Sbjct: 754 RLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEM-ARQ 812

Query: 320 EESHDEDEIRPVQQQDLHRAIEKMKKS 346
           +  +++ E++ V  +    A +K++ S
Sbjct: 813 KSGNEKGELK-VSHKHFEEAFKKVRSS 838



 Score =  124 bits (312), Expect = 1e-28
 Identities = 87/287 (30%), Positives = 138/287 (48%), Gaps = 16/287 (5%)

Query: 46  KQKVEAQKQAEKLMKQIGVKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKD 105
           K+K E  ++ +  ++ +  K  K    E  I+         +V + D+ G D     LK+
Sbjct: 229 KRKKEDLQEVDGEIEAVLQKKAKARGLEFQIS---------NVKFEDVGGND---MTLKE 276

Query: 106 TVILPIKKKHLFENSRL-LQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTD 164
              + I  +H      L + PP+GVLL+GPPGCGKTL+A A A E     + +    +  
Sbjct: 277 VCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGELDLPILKVAAPEIVS 336

Query: 165 KWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGL- 223
              GES++    +F  A+   P IIFIDEID+    R  +  +    + AQ ++  D L 
Sbjct: 337 GVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKDMERRIVAQLLTCMDDLN 396

Query: 224 DTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQREAILKLILKNENVDRH 281
           +   + +V+V+GATNRP  LD A+ R  R      +  P    RE IL+ + +   + + 
Sbjct: 397 NVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRERILQTLCRKLRLPQA 456

Query: 282 VDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEI 328
            D   +A  T GF G+DL  +CR+AA+  V   +    E+     E+
Sbjct: 457 FDFCHLAHLTPGFVGADLMALCREAAMCAVNRVLMKLQEQQKKNPEM 503


>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
          Length = 439

 Score =  146 bits (368), Expect = 3e-35
 Identities = 91/259 (35%), Positives = 140/259 (54%), Gaps = 5/259 (1%)

Query: 70  SEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGV 129
           +EY+  + A  VD       +SDI GLD  I +L + ++LP+  K  FEN  + QPPKGV
Sbjct: 166 TEYDSRVKAMEVDERPTE-QYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGI-QPPKGV 223

Query: 130 LLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSII 189
           L+YGPPG GKTL+A+A A +    F+ L    L   + G+  KL    F+LA +  PSII
Sbjct: 224 LMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSII 283

Query: 190 FIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLD-TDHSCQVIVMGATNRPQDLDSAIM 248
           FIDE+D+    R  S+      ++   + L + LD    + QV V+ ATNR   LD A++
Sbjct: 284 FIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALL 343

Query: 249 R--RMPTRFHINQPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDA 306
           R  R+  +     P  + R  I+++  +  NV   V+  E+A+ TD F+G+  K +C +A
Sbjct: 344 RSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEA 403

Query: 307 ALLCVREYVNSTSEESHDE 325
            ++ +R      + E + E
Sbjct: 404 GMIALRRGATELTHEDYME 422


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score =  145 bits (365), Expect = 7e-35
 Identities = 98/266 (36%), Positives = 150/266 (56%), Gaps = 15/266 (5%)

Query: 89  TWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAK 148
           T+  I GLD  I ++K+ + LP+K   LFE   + QP KGVLLYGPPG GKTL+A+A A 
Sbjct: 147 TYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQP-KGVLLYGPPGTGKTLLARAVAH 205

Query: 149 EAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSF----LRNRSSS 204
              C FI +  S L  K+ GE  ++   +F +A +  PSIIF+DEIDS     L   S  
Sbjct: 206 HTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGG 265

Query: 205 DHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPAL 262
           D E    M  + ++  DG +   + +VI+  ATNR   LDSA++R  R+  +     P  
Sbjct: 266 DSEVQRTM-LELLNQLDGFEATKNIKVIM--ATNRIDILDSALLRPGRIDRKIEFPPPNE 322

Query: 263 KQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVRE-YVNSTSEE 321
           + R  ILK+  +  N+ R ++L ++A+   G SG+++K +C +A +  +RE  V+ T E+
Sbjct: 323 EARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQED 382

Query: 322 SHDEDEIRPVQQQDLHR--AIEKMKK 345
              E  +  V Q+D  +  +I+K+ K
Sbjct: 383 F--EMAVAKVMQKDSEKNMSIKKLWK 406


>gi|64084766 fidgetin [Homo sapiens]
          Length = 759

 Score =  145 bits (365), Expect = 7e-35
 Identities = 91/291 (31%), Positives = 151/291 (51%), Gaps = 15/291 (5%)

Query: 66  NVKLSEYEMSIAAHLVDPLNMH-------VTWSDIAGLDDVITDLKDTVILPIKKKHLFE 118
           N  + E   +   HL+D +          V W+DIAGLD V   +K+ V+ P+ +   F 
Sbjct: 454 NHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAF- 512

Query: 119 NSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVF 178
            S L   P+ +LL+GP G GKTL+ +  A + G  F  +  S L  KW GE++K+  A F
Sbjct: 513 -SGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASF 571

Query: 179 SLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATN 238
            +A   QPS+IF+ +ID  L ++ + +H   + M+ +F+   D + T    Q++V+ AT+
Sbjct: 572 LVARCRQPSVIFVSDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATS 631

Query: 239 RPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENV---DRHVDLLEVAQETDGFS 295
           +P+++D ++ R    R  I  P    R  I+  +L   N    D+   LL   Q T+GFS
Sbjct: 632 KPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALL--VQRTEGFS 689

Query: 296 GSDLKEMCRDAALLCVREYVNSTSEESHDEDEIRPVQQQDLHRAIEKMKKS 346
           G D+  +C++A +  +   + +T   +    ++RPV  QD   A  K++ S
Sbjct: 690 GLDVAHLCQEAVVGPLHA-MPATDLSAIMPSQLRPVTYQDFENAFCKIQPS 739


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score =  144 bits (362), Expect = 2e-34
 Identities = 97/286 (33%), Positives = 156/286 (54%), Gaps = 20/286 (6%)

Query: 74  MSIAAHL--VDPLNMH--VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGV 129
           M I A L  VDP+ +   V +  + GL + I  LK+ V+ P+    +FE  ++ QPP+G 
Sbjct: 405 MKIGASLADVDPMQLDSSVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKI-QPPRGC 463

Query: 130 LLYGPPGCGKTLIAKATAKEAG-----CRFINLQPSTLTDKWYGESQKLAAAVFSLAIKL 184
           L YGPPG GKTL+A+A A E         F   + +    KW GES++    +F  A ++
Sbjct: 464 LFYGPPGTGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQM 523

Query: 185 QPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLD 244
           +PSIIF DEID     RSS   +  + + +  ++L DGLD+    +++V+GATNR   +D
Sbjct: 524 RPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDS--RGEIVVIGATNRLDSID 581

Query: 245 SAIMR--RMPTRFHINQPALKQREAILKLILKNENVDRHVD--LLEVAQETDGFSGSDLK 300
            A+ R  R    F  + P  + R+ ILK+  ++ N  + +D  L E+A+   G+ G+D+K
Sbjct: 582 PALRRPGRFDREFLFSLPDKEARKEILKIHTRDWN-PKPLDTFLEELAENCVGYCGADIK 640

Query: 301 EMCRDAALLCVRE---YVNSTSEESHDEDEIRPVQQQDLHRAIEKM 343
            +C +AAL  +R     + +TSE+   +     +  +D   A++KM
Sbjct: 641 SICAEAALCALRRRYPQIYTTSEKLQLDLSSINISAKDFEVAMQKM 686


>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
          Length = 1458

 Score =  143 bits (360), Expect = 3e-34
 Identities = 96/284 (33%), Positives = 149/284 (52%), Gaps = 18/284 (6%)

Query: 81  VDPLNMH--VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCG 138
           VDP+N+   V +  I GL   I  LK+ V+ P+    +FE  ++ QPP+G L YGPPG G
Sbjct: 388 VDPMNIDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKI-QPPRGCLFYGPPGTG 446

Query: 139 KTLIAKATAKEAG-----CRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDE 193
           KTL+A+A A E         F   + +    KW GES++    +F  A  ++PSIIF DE
Sbjct: 447 KTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDE 506

Query: 194 IDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RM 251
           ID     RSS   +  + + +  ++L DGL  D+  +++V+GATNR   +D A+ R  R 
Sbjct: 507 IDGLAPVRSSRQDQIHSSIVSTLLALMDGL--DNRGEIVVIGATNRLDSIDPALRRPGRF 564

Query: 252 PTRFHINQPALKQREAILKLILKNENVDRHVDLL-EVAQETDGFSGSDLKEMCRDAALLC 310
              F  N P  K R+ IL++  ++ N       L E+A++  G+ G+D+K +C +AAL+ 
Sbjct: 565 DREFLFNLPDQKARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIA 624

Query: 311 VREYVNSTSEESH----DEDEIRPVQQQDLHRAIEKMKKSKDAA 350
           +R         SH    D   I  +  QD + A++ +  +   A
Sbjct: 625 LRRRYPQIYASSHKLQLDVSSI-VLSAQDFYHAMQNIVPASQRA 667


>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
          Length = 753

 Score =  139 bits (350), Expect = 4e-33
 Identities = 96/270 (35%), Positives = 142/270 (52%), Gaps = 26/270 (9%)

Query: 65  KNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQ 124
           KN++ S +   I    + P    V W +I GL+DV   LK ++  P+K    F    L Q
Sbjct: 442 KNIQPSSFRSVIGLMDIKP----VDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQ 497

Query: 125 PPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKL 184
           P KGVLLYGPPGC KT + +A A    C F+++  + L   + G+S+K+ + +F  A   
Sbjct: 498 P-KGVLLYGPPGCAKTTLVRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARAS 556

Query: 185 QPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWD----GLDT-----DHSCQ----- 230
            P+I+F+DEIDS L  RS+S        +   + L +    GL T       S Q     
Sbjct: 557 TPAILFLDEIDSILGARSASKTGCDVQERVLSVLLNELDGVGLKTIERRGSKSSQQEFQE 616

Query: 231 -----VIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQREAILKLILKNENVDRHVD 283
                V+++ ATNRP  LD+A++R  R+    +I  P  K R +ILK+  K   +   V 
Sbjct: 617 VFNRSVMIIAATNRPDVLDTALLRPGRLDKIIYIPPPDHKGRLSILKVCTKTMPIGPDVS 676

Query: 284 LLEVAQETDGFSGSDLKEMCRDAALLCVRE 313
           L  +A ET  FSG+DL+ +C +AALL ++E
Sbjct: 677 LENLAAETCFFSGADLRNLCTEAALLALQE 706



 Score =  130 bits (327), Expect = 2e-30
 Identities = 91/270 (33%), Positives = 144/270 (53%), Gaps = 25/270 (9%)

Query: 93  IAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGC 152
           + GL +    L++ + LP++       +  L  P+GVLL GPPG GKT + +A A+EAG 
Sbjct: 202 LGGLSEAADSLRELLRLPLRYPRAL-TALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGA 260

Query: 153 RFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQ---PSIIFIDEIDSFLRNRSSSDHEAT 209
             + +    L     GE+++    VF  A +L    PS++F+DE+D+    R S   E+ 
Sbjct: 261 ELLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQRGSRAPESR 320

Query: 210 AMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFH----INQPALKQR 265
            +  AQ ++L DG   D   +V+V+GATNRP  LD A+  R P RF     I  P LKQR
Sbjct: 321 VV--AQVLTLLDGASGDR--EVVVVGATNRPDALDPAL--RRPGRFDREVVIGTPTLKQR 374

Query: 266 EAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDE 325
           + IL++I     +  HVDL  +A+ T G+ G+DL  +CR+AA+  +       SE++ D 
Sbjct: 375 KEILQVITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAAMHALLH-----SEKNQDN 429

Query: 326 DEIRPVQQQDLHRAIEKMKKSKDAAFQNVL 355
             I  +        +E  K  + ++F++V+
Sbjct: 430 PVIDEID------FLEAFKNIQPSSFRSVI 453


>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
           [Homo sapiens]
          Length = 414

 Score =  137 bits (346), Expect = 1e-32
 Identities = 80/232 (34%), Positives = 128/232 (55%), Gaps = 10/232 (4%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           V ++DI G+D    ++++ V LP+    L++   +  PP+GVL+YGPPGCGKT++AKA A
Sbjct: 158 VMYADIGGMDIQKQEVREAVELPLTHFELYKQIGI-DPPRGVLMYGPPGCGKTMLAKAVA 216

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNR----SS 203
                 FI +  S    K+ GE  ++   VF LA +  P+IIFIDEID+    R    + 
Sbjct: 217 HHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG 276

Query: 204 SDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPA 261
           +D E   ++  + ++  DG D + + +VI+  ATNR   LD A++R  R+  +     P 
Sbjct: 277 ADREVQRIL-LELLNQMDGFDQNVNVKVIM--ATNRADTLDPALLRPGRLDRKIEFPLPD 333

Query: 262 LKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVRE 313
            +Q+  I   I    N+   VDL +     D  SG+D+  +C+++ +L VRE
Sbjct: 334 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRE 385


>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
           sapiens]
          Length = 387

 Score =  137 bits (346), Expect = 1e-32
 Identities = 80/232 (34%), Positives = 128/232 (55%), Gaps = 10/232 (4%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           V ++DI G+D    ++++ V LP+    L++   +  PP+GVL+YGPPGCGKT++AKA A
Sbjct: 131 VMYADIGGMDIQKQEVREAVELPLTHFELYKQIGI-DPPRGVLMYGPPGCGKTMLAKAVA 189

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNR----SS 203
                 FI +  S    K+ GE  ++   VF LA +  P+IIFIDEID+    R    + 
Sbjct: 190 HHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG 249

Query: 204 SDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPA 261
           +D E   ++  + ++  DG D + + +VI+  ATNR   LD A++R  R+  +     P 
Sbjct: 250 ADREVQRIL-LELLNQMDGFDQNVNVKVIM--ATNRADTLDPALLRPGRLDRKIEFPLPD 306

Query: 262 LKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVRE 313
            +Q+  I   I    N+   VDL +     D  SG+D+  +C+++ +L VRE
Sbjct: 307 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRE 358


>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
          Length = 418

 Score =  137 bits (346), Expect = 1e-32
 Identities = 80/232 (34%), Positives = 128/232 (55%), Gaps = 10/232 (4%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           V ++DI G+D    ++++ V LP+    L++   +  PP+GVL+YGPPGCGKT++AKA A
Sbjct: 162 VMYADIGGMDIQKQEVREAVELPLTHFELYKQIGI-DPPRGVLMYGPPGCGKTMLAKAVA 220

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNR----SS 203
                 FI +  S    K+ GE  ++   VF LA +  P+IIFIDEID+    R    + 
Sbjct: 221 HHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG 280

Query: 204 SDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPA 261
           +D E   ++  + ++  DG D + + +VI+  ATNR   LD A++R  R+  +     P 
Sbjct: 281 ADREVQRIL-LELLNQMDGFDQNVNVKVIM--ATNRADTLDPALLRPGRLDRKIEFPLPD 337

Query: 262 LKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVRE 313
            +Q+  I   I    N+   VDL +     D  SG+D+  +C+++ +L VRE
Sbjct: 338 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRE 389


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score =  136 bits (342), Expect = 3e-32
 Identities = 81/228 (35%), Positives = 128/228 (56%), Gaps = 4/228 (1%)

Query: 89  TWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAK 148
           T++DI GLD+ I ++K++V LP+     +E   + +PPKGV+LYGPPG GKTL+AKA A 
Sbjct: 183 TYADIGGLDNQIQEIKESVELPLTHPEYYEEMGI-KPPKGVILYGPPGTGKTLLAKAVAN 241

Query: 149 EAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEA 208
           +    F+ +  S L  K+ G+  KL   +F +A +  PSI+FIDEID+    R  S+   
Sbjct: 242 QTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGG 301

Query: 209 TAMMKAQFMSLWDGLD-TDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPALKQR 265
              ++   + L + LD  D    V V+ ATNR + LD A++R  R+  +     P  K +
Sbjct: 302 EREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTK 361

Query: 266 EAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVRE 313
           + I ++      +   V L ++    D  SG+D+K +C +A L+ +RE
Sbjct: 362 KRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRE 409


>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score =  120 bits (302), Expect = 1e-27
 Identities = 74/231 (32%), Positives = 125/231 (54%), Gaps = 10/231 (4%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           VT+SD+ G  + I  L++ V  P+     F N  + +PPKGVLL+GPPG GKTL A+A A
Sbjct: 172 VTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGI-EPPKGVLLFGPPGTGKTLCARAVA 230

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSF----LRNRSS 203
                 FI +  S L  K+ GE  ++   +F +A   +  +IF DEID+       + + 
Sbjct: 231 NRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAG 290

Query: 204 SDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHINQPA 261
            D+E    M  + ++  DG D   + +V++  ATNRP  LD A+MR  R+  +   + P 
Sbjct: 291 GDNEVQRTM-LELINQLDGFDPRGNIKVLM--ATNRPDTLDPALMRPGRLDRKIEFSLPD 347

Query: 262 LKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVR 312
           L+ R  I K+  ++ +V+R +    +A+     +G++++ +C +A +  +R
Sbjct: 348 LEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIR 398


>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
          Length = 797

 Score =  118 bits (296), Expect = 7e-27
 Identities = 85/257 (33%), Positives = 137/257 (53%), Gaps = 22/257 (8%)

Query: 88  VTWSDIAGLDDVITDLKDTV-ILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKAT 146
           V + D+AG ++   ++ + V  L   K++    +++   PKG +L GPPG GKTL+AKAT
Sbjct: 305 VKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKI---PKGAILTGPPGTGKTLLAKAT 361

Query: 147 AKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNR----- 201
           A EA   FI +  S   + + G        +F+LA K  P I+FIDEID+  R R     
Sbjct: 362 AGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNF 421

Query: 202 -SSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHIN 258
              S+ E T     Q +   DG +T  +  V+++  TNRP  LD A++R  R   +  I 
Sbjct: 422 GGQSEQENTL---NQLLVEMDGFNT--TTNVVILAGTNRPDILDPALLRPGRFDRQIFIG 476

Query: 259 QPALKQREAILKLILKNENVDRHVDLLEVAQE----TDGFSGSDLKEMCRDAALLCVREY 314
            P +K R +I K+ L+   +D  ++  ++A++    T GFSG+D+  +C +AAL+  R +
Sbjct: 477 PPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAAR-H 535

Query: 315 VNSTSEESHDEDEIRPV 331
           ++ +  + H E  I  V
Sbjct: 536 LSDSINQKHFEQAIERV 552


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score =  117 bits (293), Expect = 2e-26
 Identities = 79/231 (34%), Positives = 120/231 (51%), Gaps = 9/231 (3%)

Query: 84   LNMH----VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGK 139
            +N+H    + W  I GL +V   L DT+ LP K   LF N  + Q   G+LLYGPPG GK
Sbjct: 829  VNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRT-GILLYGPPGTGK 887

Query: 140  TLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLR 199
            TL+A   A+E+   FI+++   L  K+ G S++    +F  A   +P I+F DE +S   
Sbjct: 888  TLLAGVIARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAP 947

Query: 200  NRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMR--RMPTRFHI 257
             R   +   T  +  Q ++  DG++      V V+ AT+RP  +D A++R  R+    + 
Sbjct: 948  RRGHDNTGVTDRVVNQLLTQLDGVEGLQG--VYVLAATSRPDLIDPALLRPGRLDKCVYC 1005

Query: 258  NQPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAAL 308
              P    R  IL ++  +  +   VDL  VA  TD F+G+DLK +  +A L
Sbjct: 1006 PPPDQVSRLEILNVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQL 1056



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 62/233 (26%), Positives = 95/233 (40%), Gaps = 30/233 (12%)

Query: 129 VLLYGPPGCGKTLIAKATAKEA----GCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKL 184
           +LL G  G GK+ +AKA  KEA          +    L  K     QK     FS A+ +
Sbjct: 595 LLLTGGKGSGKSTLAKAICKEAFDKLDAHVERVDCKALRGKRLENIQKTLEVAFSEAVWM 654

Query: 185 QPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGA-------T 237
           QPS++ +D++D      +  +HE +     Q   L   L+ D   + I MG+       +
Sbjct: 655 QPSVVLLDDLDLIAGLPAVPEHEHSPDA-VQSQRLAHALN-DMIKEFISMGSLVALIATS 712

Query: 238 NRPQDLDSAIMRRMPTRF-----HINQPALKQREAILKLILKNE-----NVDRHVDLLEV 287
              Q L   ++            HI  P  +QR  IL  ++KN+     N    +DL  V
Sbjct: 713 QSQQSLHPLLVSAQGVHIFQCVQHIQPPNQEQRCEILCNVIKNKLDCDINKFTDLDLQHV 772

Query: 288 AQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEIRPVQQQDLHRAI 340
           A+ET GF       + RD  +L  R   +  S +S    E   +   D  +A+
Sbjct: 773 AKETGGF-------VARDFTVLVDRAIHSRLSRQSISTREKLVLTTLDFQKAL 818


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score =  115 bits (289), Expect = 5e-26
 Identities = 86/269 (31%), Positives = 135/269 (50%), Gaps = 19/269 (7%)

Query: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147
           V+W D+ GL +V  ++ +T+ LP++   L     L     G+LL+GPPG GKTL+AKA A
Sbjct: 702 VSWHDVGGLQEVKKEILETIQLPLEHPELLS---LGLRRSGLLLHGPPGTGKTLLAKAVA 758

Query: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHE 207
            E    F++++   L + + G+S++    VF+ A    P IIF DE+DS   +R  S   
Sbjct: 759 TECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDS 818

Query: 208 ATAM--MKAQFMSLWDGLDTDHSCQ-VIVMGATNRPQDLDSAIMRRMPTRFH------IN 258
              M  + +Q ++  DGL   HS Q V V+GATNRP  LD A++R  P RF        N
Sbjct: 819 GGVMDRVVSQLLAELDGL---HSTQDVFVIGATNRPDLLDPALLR--PGRFDKLVFVGAN 873

Query: 259 QPALKQREAILKLILKNENVDRHVDLLEVAQ-ETDGFSGSDLKEMCRDAALLCVREYVNS 317
           +    Q   +L  I +   ++  V L+ V        +G+DL  +C DA    ++  V+ 
Sbjct: 874 EDRASQLR-VLSAITRKFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDAMTAALKRRVHD 932

Query: 318 TSEESHDEDEIRPVQQQDLHRAIEKMKKS 346
             E          +  +DL +A  +++ S
Sbjct: 933 LEEGLEPGSSALMLTMEDLLQAAARLQPS 961



 Score = 85.1 bits (209), Expect = 9e-17
 Identities = 70/280 (25%), Positives = 129/280 (46%), Gaps = 21/280 (7%)

Query: 83  PLNMHVTWSDIA--GLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKT 140
           P      WS ++  GL+ ++++L       + K  L     LL     VLL GPPGCGKT
Sbjct: 423 PSEESTLWSSLSPPGLEALVSEL-----CAVLKPRLQPGGALLTGTSSVLLRGPPGCGKT 477

Query: 141 LIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRN 200
            +  A     G   + +  S+L  +  G  +    A+FS A + +P+++ +  +D   R+
Sbjct: 478 TVVAAACSHLGLHLLKVPCSSLCAESSGAVETKLQAIFSRARRCRPAVLLLTAVDLLGRD 537

Query: 201 RSSSDHEATAMMKAQFMSLWDGLDTDHSC-QVIVMGATNRPQDLDSAIMRRMPTRFHINQ 259
           R     +A  M   + + L +  D  +SC  ++V+  T+R QDL + +    P    +  
Sbjct: 538 RDGLGEDARVMAVLRHLLLNE--DPLNSCPPLMVVATTSRAQDLPADVQTAFPHELEVPA 595

Query: 260 PALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNS-- 317
            +  QR +IL+ +  +  + + V+L ++A+   GF   DL  +   ++        NS  
Sbjct: 596 LSEGQRLSILRALTAHLPLGQEVNLAQLARRCAGFVVGDLYALLTHSSRAACTRIKNSGL 655

Query: 318 ---TSEESHDEDEI----RPVQQQDLHRAIEKMKKSKDAA 350
               +EE  DE E+     P+  +D  +A+E+++ +   A
Sbjct: 656 AGGLTEE--DEGELCAAGFPLLAEDFGQALEQLQTAHSQA 693


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,903,005
Number of Sequences: 37866
Number of extensions: 538571
Number of successful extensions: 1805
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1567
Number of HSP's gapped (non-prelim): 150
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.