Guide to the Human Genome
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Search of human proteins with 31377557

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31377557 hypothetical protein LOC131583 [Homo sapiens]
         (423 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31377557 hypothetical protein LOC131583 [Homo sapiens]             844   0.0  
gi|46409306 family with sequence similarity 43, member B [Homo s...   267   2e-71
gi|132626790 low density lipoprotein receptor adaptor protein 1 ...    57   3e-08
gi|154816208 phosphotyrosine interaction domain containing 1 iso...    47   3e-05
gi|40255260 phosphotyrosine interaction domain containing 1 isof...    47   3e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    44   2e-04
gi|21735492 protein phosphatase 1, regulatory (inhibitor) subuni...    44   3e-04
gi|31415880 protein phosphatase 1, regulatory (inhibitor) subuni...    44   3e-04
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        44   3e-04
gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]              43   5e-04
gi|239745085 PREDICTED: similar to Golgin subfamily A member 8-l...    39   0.007
gi|17975763 myelin transcription factor 1 [Homo sapiens]               39   0.012
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi...    38   0.020
gi|195947367 golgi autoantigen, golgin subfamily a, 8B [Homo sap...    38   0.020
gi|31083099 golgi autoantigen, golgin subfamily a, 8A [Homo sapi...    38   0.020
gi|239745083 PREDICTED: similar to Golgin subfamily A member 8-l...    38   0.020
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    38   0.020
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    38   0.020
gi|54144629 numb homolog isoform 4 [Homo sapiens]                      38   0.020
gi|20070356 numb homolog isoform 3 [Homo sapiens]                      38   0.020
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]        37   0.026
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]        37   0.026
gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-l...    37   0.026
gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]               37   0.026
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    37   0.026
gi|171460958 nucleolar protein 10 [Homo sapiens]                       37   0.026
gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom...    37   0.034
gi|113420848 PREDICTED: hypothetical protein [Homo sapiens]            37   0.034
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa...    37   0.034
gi|118600967 shroom family member 4 [Homo sapiens]                     37   0.044

>gi|31377557 hypothetical protein LOC131583 [Homo sapiens]
          Length = 423

 Score =  844 bits (2181), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 1   MLPWKKHKFELLAEAPPRQASKPKGYAVSLHYSALSSLARACPEGALSRVGSMFRSKRKK 60
           MLPWKKHKFELLAEAPPRQASKPKGYAVSLHYSALSSLARACPEGALSRVGSMFRSKRKK
Sbjct: 1   MLPWKKHKFELLAEAPPRQASKPKGYAVSLHYSALSSLARACPEGALSRVGSMFRSKRKK 60

Query: 61  LHITSEDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRM 120
           LHITSEDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRM
Sbjct: 61  LHITSEDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRM 120

Query: 121 VHAEERALRRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSKPEK 180
           VHAEERALRRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSKPEK
Sbjct: 121 VHAEERALRRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSKPEK 180

Query: 181 AQAMALLLYQTSANALAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPP 240
           AQAMALLLYQTSANALAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPP
Sbjct: 181 AQAMALLLYQTSANALAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPP 240

Query: 241 VERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQR 300
           VERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQR
Sbjct: 241 VERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQR 300

Query: 301 ALVVAMHFECGDLLDTLENGRGEALGGGGGSLGPGAGPPPLLLGSASDMKAELSQLISDL 360
           ALVVAMHFECGDLLDTLENGRGEALGGGGGSLGPGAGPPPLLLGSASDMKAELSQLISDL
Sbjct: 301 ALVVAMHFECGDLLDTLENGRGEALGGGGGSLGPGAGPPPLLLGSASDMKAELSQLISDL 360

Query: 361 GELSFGNDVRTLQADLRVTRLLSGDSTGSESSIEGGGPDATSATAGDSSRQADGASADEP 420
           GELSFGNDVRTLQADLRVTRLLSGDSTGSESSIEGGGPDATSATAGDSSRQADGASADEP
Sbjct: 361 GELSFGNDVRTLQADLRVTRLLSGDSTGSESSIEGGGPDATSATAGDSSRQADGASADEP 420

Query: 421 HSG 423
           HSG
Sbjct: 421 HSG 423


>gi|46409306 family with sequence similarity 43, member B [Homo
           sapiens]
          Length = 329

 Score =  267 bits (682), Expect = 2e-71
 Identities = 148/297 (49%), Positives = 198/297 (66%), Gaps = 26/297 (8%)

Query: 1   MLPWKKHKFELLAEAPPRQASKPKGYAVSLHY-SALSSLARACPE----GALSRVGSMFR 55
           MLPW+++KF L+ +       K K  +  L Y S LSS  R+CP+      L R+G +FR
Sbjct: 1   MLPWRRNKFVLVED---EAKCKAKSLSPGLAYTSLLSSFLRSCPDLLPDWPLERLGRVFR 57

Query: 56  SKRKKLHITSEDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSA 115
           S+R+K+ +  EDPTYTV YLGNA T+ A+GDGCTD AVGKIW++   G  GTKMKLT+  
Sbjct: 58  SRRQKVELNKEDPTYTVWYLGNAVTLHAKGDGCTDDAVGKIWARCGPGG-GTKMKLTLGP 116

Query: 116 QGIRMVHAEERAL-----RRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRC 170
            GIRM   E  A      RRP H YLL R+TYC AD R P+VFAWVYRH+ +HKAV+LRC
Sbjct: 117 HGIRMQPCERSAAGGSGGRRPAHAYLLPRITYCTADGRHPRVFAWVYRHQARHKAVVLRC 176

Query: 171 HAVLVSKPEKAQAMALLLYQTSANALAEFKRLKRRDDARHQQQELV----GAHTIPLVPL 226
           HAVL+++  KA+A+A LL QT+  A ++FKRL+R+ DARH +Q+ +     A ++P  PL
Sbjct: 177 HAVLLARAHKARALARLLRQTALAAFSDFKRLQRQSDARHVRQQHLRAGGAAASVPRAPL 236

Query: 227 RKLLLHGPCCYK-PPVERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEE 282
           R+ LL+  C Y+ PP ERSR AP+L SI E+      ++E +E++ EEQ  G P+ E
Sbjct: 237 RR-LLNAKCAYRPPPSERSRGAPRLSSIQEE------DEEEEEDDAEEQEGGVPQRE 286


>gi|132626790 low density lipoprotein receptor adaptor protein 1
           [Homo sapiens]
          Length = 308

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 49/174 (28%), Positives = 85/174 (48%), Gaps = 13/174 (7%)

Query: 66  EDPTYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEA-GRQGTKMKLTVSAQGIRMVHAE 124
           E   +++ YLG     Q +G+  +  A+ +I + ++A G++  K+ L VS +GI +    
Sbjct: 44  EGMLFSLKYLGMTLVEQPKGEELSAAAIKRIVATAKASGKKLQKVTLKVSPRGIILTDNL 103

Query: 125 ERALRRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSKPEKAQAM 184
              L     +Y   R++YC AD    KVFA++ + +       L CHA L +K + AQA+
Sbjct: 104 TNQLIENVSIY---RISYCTADKMHDKVFAYIAQSQHNQS---LECHAFLCTKRKMAQAV 157

Query: 185 ALLLYQTSANALAEF-----KRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHG 233
            L + Q    A  EF     +  ++RD A  +  +++GA       L+ L+  G
Sbjct: 158 TLTVAQAFKVAF-EFWQVSKEEKEKRDKASQEGGDVLGARQDCTPSLKSLVATG 210


>gi|154816208 phosphotyrosine interaction domain containing 1
           isoform 2 [Homo sapiens]
          Length = 217

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 11/154 (7%)

Query: 72  VLYLGNATTIQARG-DGCTDLAVGKIWSKSEAGRQGT---KMKLTVSAQGIRMVHAEERA 127
           V YLG  +T   +   GCT+  V ++W K    R+        L +    + + H + + 
Sbjct: 60  VTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQVWLHHLDHKG 119

Query: 128 LRRPGHL--YLLHRVTYCVADARL-PKVFAWVYRHELKHKAVMLRCHAVLVSKPEKAQAM 184
                H+  + + R+ YC AD  + P +FAWVYR      +  + CHAV      +A+ +
Sbjct: 120 -EATVHMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKL 178

Query: 185 ALLLYQTSANALAEFK---RLKRRDDARHQQQEL 215
           A  + +         K   R+     +    QEL
Sbjct: 179 AHAMMEAFRKTFHSMKSDGRIHSNSSSEEVSQEL 212


>gi|40255260 phosphotyrosine interaction domain containing 1 isoform
           1 [Homo sapiens]
          Length = 248

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 11/154 (7%)

Query: 72  VLYLGNATTIQARG-DGCTDLAVGKIWSKSEAGRQGT---KMKLTVSAQGIRMVHAEERA 127
           V YLG  +T   +   GCT+  V ++W K    R+        L +    + + H + + 
Sbjct: 91  VTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQVWLHHLDHKG 150

Query: 128 LRRPGHL--YLLHRVTYCVADARL-PKVFAWVYRHELKHKAVMLRCHAVLVSKPEKAQAM 184
                H+  + + R+ YC AD  + P +FAWVYR      +  + CHAV      +A+ +
Sbjct: 151 -EATVHMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKL 209

Query: 185 ALLLYQTSANALAEFK---RLKRRDDARHQQQEL 215
           A  + +         K   R+     +    QEL
Sbjct: 210 AHAMMEAFRKTFHSMKSDGRIHSNSSSEEVSQEL 243


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/161 (29%), Positives = 65/161 (40%), Gaps = 29/161 (18%)

Query: 208 ARHQQQELVGAH-TIPLVPLRKLLLHGPCCYKPPVERSRSAPKLG---SITEDLL----- 258
           A+ + +EL  A   +P  P     + GP    PP       P  G   ++ EDL      
Sbjct: 825 AKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININ 884

Query: 259 ------GEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRALVVAMHFECGD 312
                  E+ E+E +EEEEEE+ E   EEEE+   E +  EEE E +         E G+
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEED---EEEYFEEEEEEEEEFEEEFEEEEGE 941

Query: 313 L-----------LDTLENGRGEALGGGGGSLGPGAGPPPLL 342
           L            + LE       G  GG +  GA PPP L
Sbjct: 942 LEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTL 982



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 15/107 (14%)

Query: 213  QELVGAHTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLGSITEDLLGEQ-------LEQE 265
            +E  GA T P +    L   G       VER   +P  G   ++L+ E+       LE+E
Sbjct: 1015 EEERGADTAPTLAPEALPSQGE------VEREGESPAAGPPPQELVEEEPSAPPTLLEEE 1068

Query: 266  LQEEEEEEQP--EGCPEEEENRAAEGDPAEEEAEAQRALVVAMHFEC 310
             ++  ++ QP  E   EEE     E +  +E+ +   A ++A   +C
Sbjct: 1069 TEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDC 1115


>gi|21735492 protein phosphatase 1, regulatory (inhibitor) subunit
           1B isoform 1 [Homo sapiens]
          Length = 204

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 36/112 (32%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 234 PCCYKPP----VERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEG 289
           PC Y PP    V+R   +  L SI+   L E    E ++E  E +  G P EE+    E 
Sbjct: 71  PCAYTPPSLKAVQRIAES-HLQSISN--LNENQASEEEDELGELRELGYPREEDEEEEED 127

Query: 290 DPAEEEAEAQRALVVAMHFECGDLLDTLENGRGEALGGGGGSLGPGAGPPPL 341
           D  EEE E  +A          ++L  +    G+    G G  GP   PPPL
Sbjct: 128 DEEEEEEEDSQA----------EVLKVIRQSAGQKTTCGQGLEGPWERPPPL 169


>gi|31415880 protein phosphatase 1, regulatory (inhibitor) subunit
           1B isoform 2 [Homo sapiens]
          Length = 168

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 36/112 (32%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 234 PCCYKPP----VERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEG 289
           PC Y PP    V+R   +  L SI+   L E    E ++E  E +  G P EE+    E 
Sbjct: 35  PCAYTPPSLKAVQRIAES-HLQSISN--LNENQASEEEDELGELRELGYPREEDEEEEED 91

Query: 290 DPAEEEAEAQRALVVAMHFECGDLLDTLENGRGEALGGGGGSLGPGAGPPPL 341
           D  EEE E  +A          ++L  +    G+    G G  GP   PPPL
Sbjct: 92  DEEEEEEEDSQA----------EVLKVIRQSAGQKTTCGQGLEGPWERPPPL 133


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 43/135 (31%), Positives = 57/135 (42%), Gaps = 31/135 (22%)

Query: 259 GEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRALVVAMHFECGD------ 312
           G++ E+E +E+EEEE+ +   EEEE    E +  EEE E + A  VA+    G       
Sbjct: 731 GKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSS 790

Query: 313 ------------------LLDTLENGRGEALGGGGGSLGPGAGPPPLLLGSASDMK---- 350
                             L D  +  RG A     G L P  G   L+L S  DMK    
Sbjct: 791 EGSERSTDRSQEGAPSTLLADDQKESRGRA-SMADGDLEPEEGSKTLVLVSPGDMKKSPV 849

Query: 351 -AELSQLISDLGELS 364
            AEL+    DLG L+
Sbjct: 850 TAELAP-DPDLGTLA 863


>gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
          Length = 609

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 31/109 (28%), Positives = 52/109 (47%), Gaps = 9/109 (8%)

Query: 69  TYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRMVHAEERAL 128
           ++ V YLG+    ++RG    + AV K+      GR+  K  L VSA G+R+V  + + L
Sbjct: 79  SFPVRYLGHVEVEESRGMHVCEDAVKKL---KAMGRKSVKSVLWVSADGLRVVDDKTKDL 135

Query: 129 RRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSK 177
                   + +V++C  D  L K F+++ R     + +   CH  L  K
Sbjct: 136 LVD---QTIEKVSFCAPDRNLDKAFSYICRDGTTRRWI---CHCFLALK 178


>gi|239745085 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 3 [Homo sapiens]
          Length = 601

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 45/168 (26%), Positives = 71/168 (42%), Gaps = 16/168 (9%)

Query: 262 LEQELQEEEEEEQPEGCPEEEE--NRAAEGDPAEEEAEAQRALVVAMHFECGDLLDTLEN 319
           L  E Q+E   EQ E  PE+EE   + AE   + +E   +   V+ +  +  +L + L  
Sbjct: 338 LLNEGQKERLREQQERLPEQEERLQQLAEPQNSFKELNNENKSVLQLEQQVKELQEKLGK 397

Query: 320 GRGEALGGG----GGSLGPGAGPPPLLLGSASDMKAELSQLISDLGELSFGNDVRTLQ-- 373
                +         + GPGA  P    G +S     L +  +DL EL    ++R +Q  
Sbjct: 398 RLAHLVASAQKEPEAARGPGAPGPG---GESSSFMDHLEEK-ADLSELVKKQELRFIQYW 453

Query: 374 ---ADLRVTRLLSGDSTGSESSIEGGGPDATSATAGDSSRQADGASAD 418
                 ++  LLS     ++ +  GGG     A  GD   +A GA+AD
Sbjct: 454 QERCHQKIHHLLSEPGGRAKDAALGGGHHQAGAQGGDED-EAAGAAAD 500


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 22/60 (36%), Positives = 31/60 (51%)

Query: 240 PVERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQ 299
           P     +A +  S  + +L  + E E +EEEEEE+ E   EEEE    E +  EEE E +
Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 23/58 (39%), Positives = 31/58 (53%)

Query: 242 ERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQ 299
           E S+    L    ED   E+ E+E +E+EEEE+ E   EEEE    E +  EEE E +
Sbjct: 247 ESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 19/42 (45%), Positives = 26/42 (61%)

Query: 260 EQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRA 301
           E+ E+E ++EEEEE+ E   EEEE    E +  EEE E + A
Sbjct: 266 EEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEA 307



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 20/42 (47%), Positives = 25/42 (59%)

Query: 260 EQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRA 301
           E+ E+E  EEEEEE+ E   EEEE    E +  EEE E + A
Sbjct: 267 EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 18/37 (48%), Positives = 22/37 (59%)

Query: 255 EDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDP 291
           ED   E+ E+E +EEEEEE+ E   EEEE    E  P
Sbjct: 273 EDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 16/35 (45%), Positives = 22/35 (62%)

Query: 260 EQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEE 294
           E+ E+E +EEEEEE+ E   EEEE    E + A +
Sbjct: 276 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 17/36 (47%), Positives = 22/36 (61%)

Query: 260 EQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEE 295
           E+ E+E +EEEEEE+ E   EEEE   A  D   +E
Sbjct: 280 EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQE 315



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 17/63 (26%)

Query: 254 TEDLLGEQL-----------------EQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEA 296
           ++DL  + L                 E+E +EEEEEE+ E   EEEE    E +  EEE 
Sbjct: 232 SQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291

Query: 297 EAQ 299
           E +
Sbjct: 292 EEE 294


>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
           sapiens]
          Length = 631

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 21/43 (48%), Positives = 27/43 (62%), Gaps = 1/43 (2%)

Query: 257 LLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQ 299
           L+GE+ E E +EE+EE Q EG  EEEE    E +  EEE E +
Sbjct: 105 LVGEE-ETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEE 146



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 8/74 (10%)

Query: 230 LLHGPCCYKPPVERSRSAPKL----GSITEDLLGEQLEQELQEEEEEEQPEGCPE----E 281
           L H P   +   ER     ++    G   E+   E+ E+E +EEEEEEQP   P+     
Sbjct: 100 LFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGN 159

Query: 282 EENRAAEGDPAEEE 295
            E  + E D A EE
Sbjct: 160 HEQYSLEEDQALEE 173


>gi|195947367 golgi autoantigen, golgin subfamily a, 8B [Homo
           sapiens]
          Length = 603

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 45/175 (25%), Positives = 73/175 (41%), Gaps = 20/175 (11%)

Query: 257 LLGEQLEQELQEEEE--EEQPEGCPEEEENRAAEGDPAEEEAEAQRALVVAMHFE----- 309
           LL    ++ L+E+EE  +EQ E   E E+      +P  +  E +     A+  E     
Sbjct: 326 LLNRGQKERLREQEERLQEQQERLREREKRLQQLAEPQSDLEELKHENKSALQLEQQVKE 385

Query: 310 ----CGDLLDTLENGRGE--ALGGGGGSLGPGAGPPPLLLGSASDMKAELSQLISDLGEL 363
                G +++TL +   E  A     G+ G  +G   LL     + KA+L + +  L EL
Sbjct: 386 LQEKLGQVMETLTSAEKEPEAAVPASGTGGESSGLMDLL-----EEKADLREHVEKL-EL 439

Query: 364 SFGNDVRTLQADLRVTRLLSGDSTGSESSIEGGGPDATSATAGDSSRQADGASAD 418
            F    R  +   +V RLL+     ++ +  GGG        G    +A GA+ D
Sbjct: 440 GF-IQYRRERCHQKVHRLLTEPGDSAKDASPGGGHHQAGPGQGGEEGEAAGAAGD 493


>gi|31083099 golgi autoantigen, golgin subfamily a, 8A [Homo
           sapiens]
          Length = 603

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 45/175 (25%), Positives = 73/175 (41%), Gaps = 20/175 (11%)

Query: 257 LLGEQLEQELQEEEE--EEQPEGCPEEEENRAAEGDPAEEEAEAQRALVVAMHFE----- 309
           LL    ++ L+E+EE  +EQ E   E E+      +P  +  E +     A+  E     
Sbjct: 326 LLNRGQKERLREQEERLQEQQERLREREKRLQQLAEPQSDLEELKHENKSALQLEQQVKE 385

Query: 310 ----CGDLLDTLENGRGE--ALGGGGGSLGPGAGPPPLLLGSASDMKAELSQLISDLGEL 363
                G +++TL +   E  A     G+ G  +G   LL     + KA+L + +  L EL
Sbjct: 386 LQEKLGQVMETLTSAEKEPEAAVPASGTGGESSGLMDLL-----EEKADLREHVEKL-EL 439

Query: 364 SFGNDVRTLQADLRVTRLLSGDSTGSESSIEGGGPDATSATAGDSSRQADGASAD 418
            F    R  +   +V RLL+     ++ +  GGG        G    +A GA+ D
Sbjct: 440 GF-IQYRRERCHQKVHRLLTEPGDSAKDASPGGGHHQAGPGQGGEEGEAAGAAGD 493


>gi|239745083 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 4 [Homo sapiens]
          Length = 590

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 45/169 (26%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 262 LEQELQEEEEEEQPEGCPEEEE--NRAAEGDPAEEEAEAQRALVVAMHFECGDLLDTLEN 319
           L  E Q+E   EQ E  PE+EE   + AE   + +E   +   V+ +  +  +L + L  
Sbjct: 326 LLNEGQKERLREQQERLPEQEERLQQLAEPQNSFKELNNENKSVLQLEQQVKELQEKLGK 385

Query: 320 GRGEALGGGG-----GSLGPGAGPPPLLLGSASDMKAELSQLISDLGELSFGNDVRTLQ- 373
            +              + GPGA  P    G +S     L +  +DL EL    ++R +Q 
Sbjct: 386 VKETVTSTPSKKEPEAARGPGAPGPG---GESSSFMDHLEEK-ADLSELVKKQELRFIQY 441

Query: 374 ----ADLRVTRLLSGDSTGSESSIEGGGPDATSATAGDSSRQADGASAD 418
                  ++  LLS     ++ +  GGG     A  GD   +A GA+AD
Sbjct: 442 WQERCHQKIHHLLSEPGGRAKDAALGGGHHQAGAQGGDED-EAAGAAAD 489


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 34/119 (28%)

Query: 238 KPPVERSRSAPKLGSITEDLLGEQLEQELQE----------EEEEEQPEGCPEEEENRAA 287
           K PVE ++S  ++G       GEQ E+E +E          E++EE+P+  PE+++  + 
Sbjct: 684 KSPVEEAKSKAEVGK------GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAES- 736

Query: 288 EGDPAEEEAEAQRALV---VAMHFECGDLLDTLENGR-------GEALGGGGGSLGPGA 336
              P +EEA A+   +   V +H E     +T E G+        E  GG GGS   G+
Sbjct: 737 ---PVKEEAVAEVVTITKSVKVHLE----KETKEEGKPLQQEKEKEKAGGEGGSEEEGS 788



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 15/57 (26%)

Query: 259 GEQLEQELQEEEEEE--------------QPEGCPEEEENRAAEGDPAEEEAEAQRA 301
           GE+ E+E QEEEEEE              + EG  E+EE    EG+  E EAE + A
Sbjct: 525 GEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGE-TEAEAEGEEA 580



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 4/57 (7%)

Query: 238 KPPVERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEE 294
           +P  E    A K   + +    E  E+E ++EEEE Q E   EEEE+  A+ D AEE
Sbjct: 498 EPEAEEEEVAAKKSPV-KATAPEVKEEEGEKEEEEGQEE---EEEEDEGAKSDQAEE 550



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 4/56 (7%)

Query: 242 ERSRSAPKLGSITEDLLGEQLEQELQE-EEEEEQPEGCPEEEENRAAEGDPAEEEA 296
           E+S     L +ITE+L     E++ +  EE+EE+PE    EEE  AA+  P +  A
Sbjct: 465 EKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEA---EEEEVAAKKSPVKATA 517



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 28/128 (21%)

Query: 196 LAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLG---S 252
           +A +++L   ++ R       G+ T PL   R  +       KP VE    APKL     
Sbjct: 398 IAAYRKLLEGEETRFST--FAGSITGPLYTHRPPITISSKIQKPKVE----APKLKVQHK 451

Query: 253 ITEDLLGE-QLEQELQEEEE--------------EEQPEGCPEEEENRAAEGDPAEEEAE 297
             E+++ E ++E E  E EE              EE+ E   E+EE   AE    EEE  
Sbjct: 452 FVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAE----EEEVA 507

Query: 298 AQRALVVA 305
           A+++ V A
Sbjct: 508 AKKSPVKA 515


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 34/119 (28%)

Query: 238 KPPVERSRSAPKLGSITEDLLGEQLEQELQE----------EEEEEQPEGCPEEEENRAA 287
           K PVE ++S  ++G       GEQ E+E +E          E++EE+P+  PE+++  + 
Sbjct: 308 KSPVEEAKSKAEVGK------GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAES- 360

Query: 288 EGDPAEEEAEAQRALV---VAMHFECGDLLDTLENGR-------GEALGGGGGSLGPGA 336
              P +EEA A+   +   V +H E     +T E G+        E  GG GGS   G+
Sbjct: 361 ---PVKEEAVAEVVTITKSVKVHLE----KETKEEGKPLQQEKEKEKAGGEGGSEEEGS 412



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 15/57 (26%)

Query: 259 GEQLEQELQEEEEEE--------------QPEGCPEEEENRAAEGDPAEEEAEAQRA 301
           GE+ E+E QEEEEEE              + EG  E+EE    EG+  E EAE + A
Sbjct: 149 GEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGE-TEAEAEGEEA 204



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 4/57 (7%)

Query: 238 KPPVERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEE 294
           +P  E    A K   + +    E  E+E ++EEEE Q E   EEEE+  A+ D AEE
Sbjct: 122 EPEAEEEEVAAKKSPV-KATAPEVKEEEGEKEEEEGQEE---EEEEDEGAKSDQAEE 174



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 4/56 (7%)

Query: 242 ERSRSAPKLGSITEDLLGEQLEQELQE-EEEEEQPEGCPEEEENRAAEGDPAEEEA 296
           E+S     L +ITE+L     E++ +  EE+EE+PE    EEE  AA+  P +  A
Sbjct: 89  EKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEA---EEEEVAAKKSPVKATA 141



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 28/128 (21%)

Query: 196 LAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLG---S 252
           +A +++L   ++ R       G+ T PL   R  +       KP VE    APKL     
Sbjct: 22  IAAYRKLLEGEETRFST--FAGSITGPLYTHRPPITISSKIQKPKVE----APKLKVQHK 75

Query: 253 ITEDLLGE-QLEQELQEEEE--------------EEQPEGCPEEEENRAAEGDPAEEEAE 297
             E+++ E ++E E  E EE              EE+ E   E+EE   AE    EEE  
Sbjct: 76  FVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAE----EEEVA 131

Query: 298 AQRALVVA 305
           A+++ V A
Sbjct: 132 AKKSPVKA 139


>gi|54144629 numb homolog isoform 4 [Homo sapiens]
          Length = 592

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 26/109 (23%), Positives = 51/109 (46%), Gaps = 9/109 (8%)

Query: 69  TYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRMVHAEERAL 128
           ++ V YLG+    ++RG    + AV ++      G++  K  L VSA G+R+V  + + L
Sbjct: 38  SFPVKYLGHVEVDESRGMHICEDAVKRL---KATGKKAVKAVLWVSADGLRVVDEKTKDL 94

Query: 129 RRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSK 177
                   + +V++C  D    + F+++ R     + +   CH  +  K
Sbjct: 95  IVD---QTIEKVSFCAPDRNFDRAFSYICRDGTTRRWI---CHCFMAVK 137


>gi|20070356 numb homolog isoform 3 [Homo sapiens]
          Length = 640

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 26/109 (23%), Positives = 51/109 (46%), Gaps = 9/109 (8%)

Query: 69  TYTVLYLGNATTIQARGDGCTDLAVGKIWSKSEAGRQGTKMKLTVSAQGIRMVHAEERAL 128
           ++ V YLG+    ++RG    + AV ++      G++  K  L VSA G+R+V  + + L
Sbjct: 38  SFPVKYLGHVEVDESRGMHICEDAVKRL---KATGKKAVKAVLWVSADGLRVVDEKTKDL 94

Query: 129 RRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSK 177
                   + +V++C  D    + F+++ R     + +   CH  +  K
Sbjct: 95  IVD---QTIEKVSFCAPDRNFDRAFSYICRDGTTRRWI---CHCFMAVK 137


>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
          Length = 285

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 19/40 (47%), Positives = 24/40 (60%)

Query: 262 LEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRA 301
           +E+ ++E EEEEQ E   EE+E  A E   AE E E  RA
Sbjct: 4   IEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRA 43



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 18/40 (45%), Positives = 21/40 (52%)

Query: 260 EQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQ 299
           E+   E QEE  EE  E   E EE RA E +  EE  EA+
Sbjct: 17  EEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAE 56



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 263 EQELQEEEEEEQPEGCPEEEENRAAEGD--PAEEEAEAQRALVVAMHF 308
           +Q ++ E E+E+     EE   R  E +   AE+EA  ++AL   MHF
Sbjct: 137 QQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHF 184



 Score = 28.9 bits (63), Expect = 9.2
 Identities = 15/41 (36%), Positives = 21/41 (51%)

Query: 263 EQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRALV 303
           + E + E EE + E   EEEE + AE  P EE     R+ +
Sbjct: 31  DAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFM 71


>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
          Length = 288

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 19/40 (47%), Positives = 24/40 (60%)

Query: 262 LEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRA 301
           +E+ ++E EEEEQ E   EE+E  A E   AE E E  RA
Sbjct: 4   IEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRA 43



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 18/40 (45%), Positives = 21/40 (52%)

Query: 260 EQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQ 299
           E+   E QEE  EE  E   E EE RA E +  EE  EA+
Sbjct: 17  EEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAE 56



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 263 EQELQEEEEEEQPEGCPEEEENRAAEGD--PAEEEAEAQRALVVAMHF 308
           +Q ++ E E+E+     EE   R  E +   AE+EA  ++AL   MHF
Sbjct: 137 QQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHF 184



 Score = 28.9 bits (63), Expect = 9.2
 Identities = 15/41 (36%), Positives = 21/41 (51%)

Query: 263 EQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRALV 303
           + E + E EE + E   EEEE + AE  P EE     R+ +
Sbjct: 31  DAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFM 71


>gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 [Homo sapiens]
          Length = 602

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 17/174 (9%)

Query: 257 LLGEQLEQELQEEEE--EEQPEGCPEEEENRAAEGDP----AEEEAEAQRAL-----VVA 305
           LL ++ E+ +QE+EE   +Q E   E+ ++      P     E   E + AL     V  
Sbjct: 333 LLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVKE 392

Query: 306 MHFECGDLLDTLENGRGE-ALGGGGGSLGPGAGPPPLLLGSASDMKAELSQLISDLGELS 364
           +  + G++ +T  + + E     G G+ GPG      +     + KA+LS+L+    EL 
Sbjct: 393 LQEKLGEVKETETSAQKEPEAARGPGAPGPGGESSSFM--DHLEEKADLSELVKK-KELC 449

Query: 365 FGNDVRTLQADLRVTRLLSGDSTGSESSIEGGGPDATSATAGDSSRQADGASAD 418
           F +  R  +   +   LLS     ++ +  GGG     A  GD   +A GA+AD
Sbjct: 450 FIHHWRD-RCHQKTHHLLSEPGGRAKDAALGGGHHQAGAQGGDEG-EAAGAAAD 501


>gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]
          Length = 110

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 2/60 (3%)

Query: 242 ERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRA 301
           E  R AP  G+  E+   ++ + E+ EEEEE   E   EEEE    E +  +E+ EA+ A
Sbjct: 28  ENGRDAPANGNANEENGEQEADNEVDEEEEEGGEE--EEEEEEGDGEEEDGDEDEEAESA 85


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 32/97 (32%), Positives = 41/97 (42%), Gaps = 2/97 (2%)

Query: 242 ERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGD-PAEEEAEAQR 300
           E+       G   E+  GE+ E+E + E EEE+ EG  EE E    EG+   EEE E   
Sbjct: 807 EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE 866

Query: 301 ALVVAMHFECGDLLDTLENGRGEALGGGGGSLGPGAG 337
                   E G+  +    G GE  G G G    G G
Sbjct: 867 GEEEGEEGE-GEGEEEEGEGEGEEEGEGEGEEEEGEG 902



 Score = 35.8 bits (81), Expect = 0.075
 Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 9/79 (11%)

Query: 259 GEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRALVVAMHFECGDLLDTLE 318
           GE+ E E + EEE E+ EG  EEEE    EG+  E E E +         E         
Sbjct: 912 GEEEEGEGKGEEEGEEGEGEGEEEEGE-GEGEDGEGEGEEEEGEWEGEEEE--------G 962

Query: 319 NGRGEALGGGGGSLGPGAG 337
            G GE  G G G  G G G
Sbjct: 963 EGEGEEEGEGEGEEGEGEG 981



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 42/140 (30%), Positives = 56/140 (40%), Gaps = 29/140 (20%)

Query: 196 LAEFKRLKRRDDARHQQQELVGAHTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLGSITE 255
           LAE +  K+RD    +Q+E    H                      ER++   + G   E
Sbjct: 696 LAEKEEWKKRDGEEQEQKEREQGHQ--------------------KERNQEMEEGG---E 732

Query: 256 DLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAE---AQRALVVAMHFECGD 312
           +  GE  E+E   EEEEE+     EE E    EG+  +EE E    +RA       E GD
Sbjct: 733 EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGD 792

Query: 313 LLDTLE---NGRGEALGGGG 329
             +  E    GRGE    GG
Sbjct: 793 QGEGEEEETEGRGEEKEEGG 812



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 31/79 (39%), Positives = 38/79 (48%), Gaps = 10/79 (12%)

Query: 255  EDLLGEQLEQELQEEEEEEQPEGCPEEE---ENRAAEGDPAEEEAEAQRALVVAMHFECG 311
            ED  GE  E+E + E EEE+ EG  EEE   E    EG+  EEE E +         E G
Sbjct: 942  EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEG------EEEEG 995

Query: 312  DLLDTLENGRGEALGGGGG 330
            +  +  E G GE  G G G
Sbjct: 996  E-EEGEEEGEGEEEGEGEG 1013



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 5/76 (6%)

Query: 251  GSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRALVVAMHFEC 310
            G   E+  GE  E E + EEEE + EG  EE E    E    EEE E +         E 
Sbjct: 964  GEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGE-----GEEEEE 1018

Query: 311  GDLLDTLENGRGEALG 326
            G++   +E   GE  G
Sbjct: 1019 GEVEGEVEGEEGEGEG 1034



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 3/52 (5%)

Query: 251  GSITEDLLGEQLEQELQEEEEEEQPEGCPEE---EENRAAEGDPAEEEAEAQ 299
            G +  ++ GE+ E E +EEE EE+ E   +E   EENR    +  EEE + Q
Sbjct: 1019 GEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQ 1070



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 13/94 (13%)

Query: 259 GEQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRALVVAMHFECGDLLDTLE 318
           GE+  +E + E EEE+ EG  EEE     EG+  EEE E +         E G+     E
Sbjct: 867 GEEEGEEGEGEGEEEEGEGEGEEE----GEGEGEEEEGEGEGE-------EEGE--GEGE 913

Query: 319 NGRGEALGGGGGSLGPGAGPPPLLLGSASDMKAE 352
              GE  G   G  G G G      G   D + E
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 1/40 (2%)

Query: 260  EQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQ 299
            E+ E E++ E E E+ EG  EEEE    EG+  E+E E +
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEGEE-EGEEREKEGEGE 1053


>gi|171460958 nucleolar protein 10 [Homo sapiens]
          Length = 688

 Score = 37.4 bits (85), Expect = 0.026
 Identities = 19/43 (44%), Positives = 27/43 (62%), Gaps = 2/43 (4%)

Query: 263 EQELQEEEEEEQPEGCPEEEENRAAEGDPAE--EEAEAQRALV 303
           +QEL+E+EEEE+PEG P + E+  +  D     EE   QR L+
Sbjct: 526 QQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLL 568


>gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo
           sapiens]
          Length = 304

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 33/148 (22%), Positives = 65/148 (43%), Gaps = 14/148 (9%)

Query: 70  YTVLYLGNATTIQARGDGCTDLAVGKI----WSKSEAGRQGTKMKLTVSAQGIRMVHAEE 125
           Y   +LG+    Q +G      AV K+      K   G++  K++L +S  G++++  + 
Sbjct: 27  YNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKT 86

Query: 126 RALRRPGHLYLLHRVTYCVADARLPKVFAWVYRHELKHKAVMLRCHAVLVSKPEK-AQAM 184
           + ++   H   LHR+++C  D    ++F ++ +    +K      H   V   EK A+ +
Sbjct: 87  KEVQ---HNCQLHRISFCADDKTDKRIFTFICKDSESNK------HLCYVFDSEKCAEEI 137

Query: 185 ALLLYQTSANALAEFKRLKRRDDARHQQ 212
            L + Q    A  +F     +D    +Q
Sbjct: 138 TLTIGQAFDLAYRKFLESGGKDVETRKQ 165


>gi|113420848 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 109

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 7/60 (11%)

Query: 242 ERSRSAPKLGSITEDLLGEQLEQELQEEEEEEQPEGCPEEEENRAAEG---DPAEEEAEA 298
           E  R AP  G+  E    E  EQE  +E +EE  E   EEEE +  +G   D  EEEAE+
Sbjct: 28  ENGRDAPANGNANE----ENGEQEADKEVDEEGEESGEEEEEEKEGDGEEEDGDEEEAES 83


>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
            sapiens]
          Length = 1925

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 28/87 (32%), Positives = 43/87 (49%), Gaps = 5/87 (5%)

Query: 219  HTIPLVPLRKLLLHGPCCYKPPVERSRSAPKLGSITE--DLLGEQLEQELQEEEEEEQPE 276
            + +P++P+           +P  +R    P LG   E  +  GE+ E+EL+EEEEEE+  
Sbjct: 1726 YLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEE- 1784

Query: 277  GCPEEEENRAAEGDPAEEEAEAQRALV 303
               EEEE    E +  EEE + +   V
Sbjct: 1785 --TEEEELGKEEIEEKEEERDEKEEKV 1809


>gi|118600967 shroom family member 4 [Homo sapiens]
          Length = 1493

 Score = 36.6 bits (83), Expect = 0.044
 Identities = 18/40 (45%), Positives = 24/40 (60%)

Query: 260  EQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQ 299
            +Q +Q+ Q+EEEEE+ E   EEEE    E +  EEE   Q
Sbjct: 1123 QQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQ 1162



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 16/38 (42%), Positives = 25/38 (65%)

Query: 260  EQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAE 297
            +Q +Q+ Q++++EE+ E   EEEE    E + AEEE E
Sbjct: 1120 QQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEE 1157



 Score = 32.7 bits (73), Expect = 0.64
 Identities = 15/46 (32%), Positives = 27/46 (58%)

Query: 263  EQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAEAQRALVVAMHF 308
            +Q+ Q++++++Q E   EEEE    E +  EEEAE +   +   +F
Sbjct: 1119 QQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYF 1164



 Score = 32.3 bits (72), Expect = 0.83
 Identities = 15/38 (39%), Positives = 24/38 (63%)

Query: 260  EQLEQELQEEEEEEQPEGCPEEEENRAAEGDPAEEEAE 297
            ++ +Q+ Q+++EEE+ E   EEEE    E +  EEE E
Sbjct: 1121 QKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEE 1158


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,797,152
Number of Sequences: 37866
Number of extensions: 892326
Number of successful extensions: 13635
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 214
Number of HSP's successfully gapped in prelim test: 234
Number of HSP's that attempted gapping in prelim test: 8703
Number of HSP's gapped (non-prelim): 2931
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press