Search of human proteins with 31317263

Search of human proteins with 31317263

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31317263 tafazzin isoform 4 [Homo sapiens]
         (248 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31317263 tafazzin isoform 4 [Homo sapiens]                         531   e-151
gi|31317259 tafazzin isoform 2 [Homo sapiens]                         522   e-148
gi|31317261 tafazzin isoform 3 [Homo sapiens]                         516   e-147
gi|4507371 tafazzin isoform 1 [Homo sapiens]                          506   e-144
gi|116268093 taste receptor, type 2, member 41 [Homo sapiens]          30   2.5  
gi|5454102 transforming, acidic coiled-coil containing protein 3...    29   3.3  
gi|4502281 Na+/K+ -ATPase beta 3 subunit [Homo sapiens]                29   3.3  
gi|239755565 PREDICTED: hypothetical protein [Homo sapiens]            28   5.7  
gi|239750071 PREDICTED: hypothetical protein XP_002347270 [Homo ...    28   5.7  
gi|239744380 PREDICTED: hypothetical protein XP_002343131 [Homo ...    28   5.7  
gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]     28   5.7  
gi|42794273 F-box and leucine-rich repeat protein 22 [Homo sapiens]    28   5.7  
gi|223278356 glutamate receptor, ionotropic, N-methyl-D-aspartat...    28   9.7  
gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens]      28   9.7  
gi|94421471 ring finger protein 17 [Homo sapiens]                      28   9.7  

>gi|31317263 tafazzin isoform 4 [Homo sapiens]
          Length = 248

 Score =  531 bits (1369), Expect = e-151
 Identities = 248/248 (100%), Positives = 248/248 (100%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCRGDGVYQKGMDFILEKLNHGDWVHIFPEGIGRLIAECHLNPIILPLWHVGMNDVLPNS 180
           VCRGDGVYQKGMDFILEKLNHGDWVHIFPEGIGRLIAECHLNPIILPLWHVGMNDVLPNS
Sbjct: 121 VCRGDGVYQKGMDFILEKLNHGDWVHIFPEGIGRLIAECHLNPIILPLWHVGMNDVLPNS 180

Query: 181 PPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQL 240
           PPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQL
Sbjct: 181 PPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQL 240

Query: 241 HNHLQPGR 248
           HNHLQPGR
Sbjct: 241 HNHLQPGR 248


>gi|31317259 tafazzin isoform 2 [Homo sapiens]
          Length = 262

 Score =  522 bits (1344), Expect = e-148
 Identities = 248/262 (94%), Positives = 248/262 (94%), Gaps = 14/262 (5%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCRGDGVYQKGMDFILEKLNHGDWVHIFPE--------------GIGRLIAECHLNPIIL 166
           VCRGDGVYQKGMDFILEKLNHGDWVHIFPE              GIGRLIAECHLNPIIL
Sbjct: 121 VCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIIL 180

Query: 167 PLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFI 226
           PLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFI
Sbjct: 181 PLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFI 240

Query: 227 QEEFQHLKTQAEQLHNHLQPGR 248
           QEEFQHLKTQAEQLHNHLQPGR
Sbjct: 241 QEEFQHLKTQAEQLHNHLQPGR 262


>gi|31317261 tafazzin isoform 3 [Homo sapiens]
          Length = 278

 Score =  516 bits (1328), Expect = e-147
 Identities = 248/278 (89%), Positives = 248/278 (89%), Gaps = 30/278 (10%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCR------------------------------GDGVYQKGMDFILEKLNHGDWVHIFPE 150
           VCR                              GDGVYQKGMDFILEKLNHGDWVHIFPE
Sbjct: 121 VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE 180

Query: 151 GIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRA 210
           GIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRA
Sbjct: 181 GIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRA 240

Query: 211 ENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 248
           ENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR
Sbjct: 241 ENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 278


>gi|4507371 tafazzin isoform 1 [Homo sapiens]
          Length = 292

 Score =  506 bits (1303), Expect = e-144
 Identities = 248/292 (84%), Positives = 248/292 (84%), Gaps = 44/292 (15%)

Query: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60
           MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA
Sbjct: 1   MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPA 60

Query: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120
           TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP
Sbjct: 61  TPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVP 120

Query: 121 VCR------------------------------GDGVYQKGMDFILEKLNHGDWVHIFPE 150
           VCR                              GDGVYQKGMDFILEKLNHGDWVHIFPE
Sbjct: 121 VCRGAEFFQAENEGKGVLDTGRHMPGAGKRREKGDGVYQKGMDFILEKLNHGDWVHIFPE 180

Query: 151 --------------GIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 196
                         GIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG
Sbjct: 181 GKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIG 240

Query: 197 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 248
           KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR
Sbjct: 241 KPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR 292


>gi|116268093 taste receptor, type 2, member 41 [Homo sapiens]
          Length = 307

 Score = 29.6 bits (65), Expect = 2.5
 Identities = 14/36 (38%), Positives = 18/36 (50%), Gaps = 2/36 (5%)

Query: 3   LHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKY 38
           L +KW FP   P  W L  SV++  + T   FW  Y
Sbjct: 120 LWLKWRFPGWVP--WLLLGSVLISFIITLLFFWVNY 153


>gi|5454102 transforming, acidic coiled-coil containing protein 3
           [Homo sapiens]
          Length = 838

 Score = 29.3 bits (64), Expect = 3.3
 Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 11/65 (16%)

Query: 177 LPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQ 236
           +P  PP  P  G       G P S  P+++ L+   K    + KA     QEE + L+++
Sbjct: 613 VPGPPPGVPAPG-------GPPLSTGPIVDLLQYSQKDLDAVVKAT----QEENRELRSR 661

Query: 237 AEQLH 241
            E+LH
Sbjct: 662 CEELH 666


>gi|4502281 Na+/K+ -ATPase beta 3 subunit [Homo sapiens]
          Length = 279

 Score = 29.3 bits (64), Expect = 3.3
 Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 9/79 (11%)

Query: 128 YQKGMDFILEKLNHGDWVHIFPEGIGRL--IAECHLNPIILPLWHVGMNDVLPNSPPYFP 185
           Y +G   IL K+N    + + PEG+ R+  +++    P +    H GM D+      YFP
Sbjct: 164 YSQGNPCILVKMNR--IIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDL-----KYFP 216

Query: 186 RFGQKITVLIGKPFSALPV 204
            +G+K+ V   +P  A+ V
Sbjct: 217 YYGKKLHVGYLQPLVAVQV 235


>gi|239755565 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 257

 Score = 28.5 bits (62), Expect = 5.7
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 68  NHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGV 127
           ++Q+ +   +L G L LRH ++   M  T   + + + K   S  F   +    C G  V
Sbjct: 4   DNQTVISKDYLQGGLLLRHDYD-HFMNATSGISPLAWRKMKVSRGFCQAQAGAYCLGAYV 62

Query: 128 YQKGMDFIL 136
           Y +G+D +L
Sbjct: 63  YHEGIDVVL 71


>gi|239750071 PREDICTED: hypothetical protein XP_002347270 [Homo
           sapiens]
          Length = 257

 Score = 28.5 bits (62), Expect = 5.7
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 68  NHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGV 127
           ++Q+ +   +L G L LRH ++   M  T   + + + K   S  F   +    C G  V
Sbjct: 4   DNQTVISKDYLQGGLLLRHDYD-HFMNATSGISPLAWRKMKVSRGFCQAQAGAYCLGAYV 62

Query: 128 YQKGMDFIL 136
           Y +G+D +L
Sbjct: 63  YHEGIDVVL 71


>gi|239744380 PREDICTED: hypothetical protein XP_002343131 [Homo
           sapiens]
          Length = 257

 Score = 28.5 bits (62), Expect = 5.7
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 68  NHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGV 127
           ++Q+ +   +L G L LRH ++   M  T   + + + K   S  F   +    C G  V
Sbjct: 4   DNQTVISKDYLQGGLLLRHDYD-HFMNATSGISPLAWRKMKVSRGFCQAQAGAYCLGAYV 62

Query: 128 YQKGMDFIL 136
           Y +G+D +L
Sbjct: 63  YHEGIDVVL 71


>gi|13376146 zinc finger and BTB domain containing 3 [Homo
          sapiens]
          Length = 574

 Score = 28.5 bits (62), Expect = 5.7
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 10/62 (16%)

Query: 6  KWPFPAVPPLTWTLASSVVMGLVGTY------SCFWTKYMNHLTV----HNREVLYELIE 55
          KW   A P   W    S++ G VG Y        FW  + +  T+    H++++L  L E
Sbjct: 7  KWGVEASPGKAWERKRSLLRGAVGRYRGATGGDLFWAPFPSWGTMEFPEHSQQLLQSLRE 66

Query: 56 KR 57
          +R
Sbjct: 67 QR 68


>gi|42794273 F-box and leucine-rich repeat protein 22 [Homo
          sapiens]
          Length = 241

 Score = 28.5 bits (62), Expect = 5.7
 Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 3/54 (5%)

Query: 41 HLTVHNREVLYEL---IEKRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLK 91
          H+T  NRE L  L   ++K    +   T S      +DP LW +L  R +  L+
Sbjct: 2  HITQLNRECLLHLFSFLDKDSRKSLARTCSQLHDVFEDPALWSLLHFRSLTELQ 55


>gi|223278356 glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
            [Homo sapiens]
          Length = 1115

 Score = 27.7 bits (60), Expect = 9.7
 Identities = 18/67 (26%), Positives = 36/67 (53%), Gaps = 7/67 (10%)

Query: 187  FGQKITVLIGKPFSALPVLERLRAENK------SAVEMRKAL-TDFIQEEFQHLKTQAEQ 239
            FG  I   IG+      +L R++ ++K      ++  + +A+ T FI+E+ QH KT+  +
Sbjct: 942  FGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRLHRAINTSFIEEKQQHFKTKRVE 1001

Query: 240  LHNHLQP 246
              +++ P
Sbjct: 1002 KRSNVGP 1008


>gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens]
          Length = 1278

 Score = 27.7 bits (60), Expect = 9.7
 Identities = 14/37 (37%), Positives = 16/37 (43%), Gaps = 5/37 (13%)

Query: 8   PFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTV 44
           P P  PP  WT     ++GL   Y   W  YM  L V
Sbjct: 251 PQPPPPPAPWT-----ILGLDAMYVIMWITYMAFLLV 282


>gi|94421471 ring finger protein 17 [Homo sapiens]
          Length = 1623

 Score = 27.7 bits (60), Expect = 9.7
 Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 2/59 (3%)

Query: 108  LHSHFFSLGKCVPVCRGDGVYQKGMDFILEKLNHGDWVHIFPEGIGRLIAECHLNPIIL 166
            L  +F+  G+   V   D ++ +G   ++E +     V     G    I +CHL PI+L
Sbjct: 1224 LEPYFWKKGEACAVRGSDTLWYRGK--VMEVVGGAVRVQYLDHGFTEKIPQCHLYPILL 1280


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.141    0.472 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,012,348
Number of Sequences: 37866
Number of extensions: 502102
Number of successful extensions: 1567
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1558
Number of HSP's gapped (non-prelim): 18
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.