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Search of human proteins with 31083351
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31083351 Sec6 protein [Homo sapiens]
(745 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31083351 Sec6 protein [Homo sapiens] 1459 0.0
gi|106879204 exocyst complex component 3-like [Homo sapiens] 332 8e-91
gi|117938266 hypothetical protein LOC91828 [Homo sapiens] 146 8e-35
gi|26051240 tumor necrosis factor, alpha-induced protein 2 [Homo... 145 2e-34
gi|226371708 exocyst complex component 3-like 2 [Homo sapiens] 133 5e-31
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 45 2e-04
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 45 2e-04
gi|212276078 leucine rich repeat (in FLII) interacting protein 1... 40 0.006
gi|71061468 centromere protein E [Homo sapiens] 39 0.023
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 37 0.067
gi|32454739 tripartite motif-containing 3 [Homo sapiens] 36 0.11
gi|32454737 tripartite motif-containing 3 [Homo sapiens] 36 0.11
gi|110611218 ribosome binding protein 1 [Homo sapiens] 36 0.15
gi|110611220 ribosome binding protein 1 [Homo sapiens] 36 0.15
gi|229577185 epidermal growth factor receptor pathway substrate ... 35 0.25
gi|4503593 epidermal growth factor receptor pathway substrate 15... 35 0.25
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 34 0.43
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 34 0.56
gi|18641360 collectin sub-family member 12 [Homo sapiens] 33 0.74
gi|7662230 ring finger protein 40 [Homo sapiens] 33 0.74
gi|118498362 kinectin 1 isoform b [Homo sapiens] 33 0.96
gi|169169865 PREDICTED: hypothetical protein LOC285754 [Homo sap... 33 0.96
gi|169168870 PREDICTED: hypothetical protein LOC285754 [Homo sap... 33 0.96
gi|169169319 PREDICTED: hypothetical protein LOC285754 [Homo sap... 33 0.96
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 33 0.96
gi|34577114 cytomatrix protein p110 [Homo sapiens] 33 0.96
gi|21264345 peripherin [Homo sapiens] 33 0.96
gi|21614525 glypican 4 [Homo sapiens] 33 0.96
gi|62243374 MAD1-like 1 protein [Homo sapiens] 33 1.3
gi|62243369 MAD1-like 1 protein [Homo sapiens] 33 1.3
>gi|31083351 Sec6 protein [Homo sapiens]
Length = 745
Score = 1459 bits (3778), Expect = 0.0
Identities = 745/745 (100%), Positives = 745/745 (100%)
Query: 1 MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRT 60
MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRT
Sbjct: 1 MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRT 60
Query: 61 GLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIF 120
GLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIF
Sbjct: 61 GLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIF 120
Query: 121 SVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGST 180
SVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGST
Sbjct: 121 SVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGST 180
Query: 181 QGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGR 240
QGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGR
Sbjct: 181 QGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGR 240
Query: 241 PKNWKEKMFTILERTVTTRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLIVAKNLMVQC 300
PKNWKEKMFTILERTVTTRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLIVAKNLMVQC
Sbjct: 241 PKNWKEKMFTILERTVTTRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLIVAKNLMVQC 300
Query: 301 FPPHYEIFKNLLNMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSTEMMRNVELAP 360
FPPHYEIFKNLLNMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSTEMMRNVELAP
Sbjct: 301 FPPHYEIFKNLLNMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSTEMMRNVELAP 360
Query: 361 EVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKETEPEADQDGYY 420
EVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKETEPEADQDGYY
Sbjct: 361 EVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKETEPEADQDGYY 420
Query: 421 QTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRNR 480
QTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRNR
Sbjct: 421 QTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRNR 480
Query: 481 QHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEEGVSPSQPSMDGILDAIAKEGCS 540
QHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEEGVSPSQPSMDGILDAIAKEGCS
Sbjct: 481 QHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEEGVSPSQPSMDGILDAIAKEGCS 540
Query: 541 GLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHR 600
GLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHR
Sbjct: 541 GLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHR 600
Query: 601 RVVVEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLRFLFRKLASGFGEDVDGYCDTIV 660
RVVVEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLRFLFRKLASGFGEDVDGYCDTIV
Sbjct: 601 RVVVEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLRFLFRKLASGFGEDVDGYCDTIV 660
Query: 661 AVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASRDMKQTIMETLEQGPA 720
AVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASRDMKQTIMETLEQGPA
Sbjct: 661 AVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASRDMKQTIMETLEQGPA 720
Query: 721 QASPSYVPLFKDIVVPSLNVAKLLK 745
QASPSYVPLFKDIVVPSLNVAKLLK
Sbjct: 721 QASPSYVPLFKDIVVPSLNVAKLLK 745
>gi|106879204 exocyst complex component 3-like [Homo sapiens]
Length = 746
Score = 332 bits (851), Expect = 8e-91
Identities = 217/746 (29%), Positives = 384/746 (51%), Gaps = 38/746 (5%)
Query: 2 KETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTG 61
+ ++ A A++ +G+ RP+QL ++ QYR RE ++ S+E+RLK+ +QS L+GV+TG
Sbjct: 23 ERAEQLARGAALKWASGIFYRPEQLARLGQYRSREVQRTCSLESRLKSVMQSYLEGVQTG 82
Query: 62 LSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFS 121
+ QL A+ V+ +++L+ + +++L+ +++ V QH QL A L + +
Sbjct: 83 VWQLAQAIEVVQGTREALSQARGLLQGMSQALQTLEPLRERVAQHKQLQALSHLLPRLRA 142
Query: 122 VPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGSTQ 181
VP V TQ LI+ L+A+ L +LE R+ ++ + + L+ G
Sbjct: 143 VPAAVSHTQTLIDGQQFLEAYVSLRELEQLREDTWAPLGGLELPVFQGLDLLFEALGQAV 202
Query: 182 GLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGRP 241
+ A +L R DP LLV+ VR+ E E R G VP
Sbjct: 203 EAAAGAAGKL----------AREDPALLVAAVRVAEVET-------GRTTPLGQVP---- 241
Query: 242 KNWKEKMFTILERTVTTRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLIVAKNLMVQCF 301
++W+++ L+ + G+ L LE +R + +L A+ L+ C
Sbjct: 242 RDWRQRCLRALQEGLEQAHFGSPLLPAPGA---LPGWLEALRVALPVELATAEALVAPCC 298
Query: 302 PPHYEIFKNLLNMYHQALSTRMQDL-ASEDLEANEIVSLLTWVLNTYTSTEMMRNVELAP 360
PP Y + + + H L +Q+L A +LEA + +LL W L+ Y EMM ++EL P
Sbjct: 299 PPQYNVVQLWAHTLHSGLRRSLQNLLAGPELEAADAFALLHWALHVYLGQEMMGSLELGP 358
Query: 361 EVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKETEPEADQDGYY 420
E DV LEPLL+ + +L T+++ + +++ WL+ AL+ + +W +E P D G Y
Sbjct: 359 EADVSQLEPLLTLENIEQLEATFVANIQASVSQWLQNALDGEVAEWGREHGPNTDPSGSY 418
Query: 421 QTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRNR 480
+ +PAIV Q+ E+N++VA+ +SE L+ +V + L ++ +FL + D + +H R +
Sbjct: 419 YSPMPAIVLQILEENIRVASLVSESLQQRVHGMALSELGTFLRSFSDALIRFSRDHFRGK 478
Query: 481 QHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEEGVSPSQPSMDGILDAIAKEGCS 540
YV Y++A +N+ S+ L +++ S + ++ LD + +
Sbjct: 479 SMAPHYVPYLLAALNHKSALSSSVSVL-------QLDGAPSGALAPVEAALDELQRRIYR 531
Query: 541 GLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHR 600
+LE + +L+ +L +++WL + +C + DF +++ P + + AEA R
Sbjct: 532 LVLEALQAELQPLFADLPSRQWLSSPELLQSVCERTGRFCRDFWRVRNPTVQLLLAEAER 591
Query: 601 RVVVEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLRFLFRKLASGFGEDVDGYC-DTI 659
VV++YL A+MQ R+ R +ER + AE++ +A QL+ LF L G + + +C +
Sbjct: 592 AVVLQYLSALMQGRLVCRGADERTQAAERLRHDAAQLQQLFLSL----GLEENAHCAPVL 647
Query: 660 VAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASRDMKQTIMETLEQG- 718
+A+ E++ L DP+LL LEV+ L ++PD+ +DH+ ALL +RGD SR+ + +L+
Sbjct: 648 LALRELLNLRDPALLGLEVAGLRQQFPDVSEDHVSALLGLRGDLSREQHLAALSSLQAAL 707
Query: 719 PAQASPSYVPLFKDIVVPSLNVAKLL 744
P S LF + P+L A L
Sbjct: 708 PPSPRASRRVLFSLVPAPALAPASCL 733
>gi|117938266 hypothetical protein LOC91828 [Homo sapiens]
Length = 722
Score = 146 bits (368), Expect = 8e-35
Identities = 187/765 (24%), Positives = 318/765 (41%), Gaps = 111/765 (14%)
Query: 20 LQRPDQLDK----VEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDI 75
LQ P + ++ + RR +RK+ + + DG R GL L A +
Sbjct: 13 LQSPKEAEEPQTPAQGSRRTSSRKEPNAHRK---------DGTRLGLGSLRQAFSRAS-- 61
Query: 76 QQSLADVSKD---------------WRQSIN----------TIESLKDVKDAVVQHSQLA 110
Q++L VSK+ +RQ++N T E V + V Q +
Sbjct: 62 QRALTQVSKEDTGLFRRSSCSLFRSFRQALNDGPATGHSQATPEVPSGVMNGVSQQASTG 121
Query: 111 AAVENLKNIFSVPEIV-RETQDLIEQGALLQAHRKLMDLE----CSRDGLMYEQYRMDSG 165
AA E LK PE + DLI + LL A +L+ LE + +EQ
Sbjct: 122 AASEELK-----PEAEGKSVADLITERQLLAAFEQLLRLETLLVAEKASRTFEQ------ 170
Query: 166 NTRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRR 225
D T L D LA ++ +++ +L + D L + R++ EE+
Sbjct: 171 ---DPTAFARRAMDVCLLYDGLAAEIGAIVRETLDSDGVDAAALAELARVVSAEEEAHPS 227
Query: 226 ILDRKKQTGFVPPGRPKNWKEKMFTILERTVTTRIEGTQADTRESDK---MWLVRHLEII 282
D F+ P+ W++ + R+ R+ A + L + L +
Sbjct: 228 PPD---DGDFLRT--PRRWRQHWEEAVRRSAQERVRRPGAGWAFGEAEGASGLAQLLAEL 282
Query: 283 RKYVLDDLIVAKNLMVQCFP----PHYEIFKNLLNMYHQALSTRMQDLASEDLEANEIVS 338
V DL + + + P +E++ L +H A++ R+Q+LA + ++
Sbjct: 283 GGLVRRDLQKVRQEVQPAYAAAGFPAWEVY---LRAFHSAVAQRLQELARDARGCEQLYI 339
Query: 339 LLTWVLNTYTSTEMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKA 398
LL W N Y S + + LA + L PLL+P V + L Y S L + I +
Sbjct: 340 LLDWAANVYGSPDFLGAPGLALPAE--PLPPLLAPDVWARLESDYTSFLEAKIASCFDSI 397
Query: 399 LETDKKDWVKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQM 458
L+ ++ W PE Q G YQ L V + ++++ A IS +L+ L +C + +
Sbjct: 398 LQLEQSHWAAAEVPEVLQ-GLYQAPLSMDVHMLVAEHVKAAGAISAELEATTLRICTRAL 456
Query: 459 NSFLSRYKDEAQLYKEEHLRNRQHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEE 518
F+ R+ ++A L E PH + A IN C+ + S++S + + E+E+
Sbjct: 457 GLFVPRF-EKAFLASEAV----SEPH-----LGAYINACEELRTSLLS-RFPGTQEELEK 505
Query: 519 GVSPSQPSMDGILDAIAKEGCSGLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVED 578
+ + S LL+ + +L+ + T+ WL + + + V
Sbjct: 506 PLVTATCSFQ-----------KHLLQGLQRELQPLFRVVCTRDWLT-QDWLHPLMDKVVT 553
Query: 579 YFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLR 638
+ ++ +P + E HR VV EYL ++ R FR E R G++KM +A+ +
Sbjct: 554 FAGHLQRVARPRAQETLQEVHRFVVREYLARALRPRERFRGME-RMHGSQKMSLDAQAIS 612
Query: 639 FLFRKLASGFGEDVDGYCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLA 698
F+ G G + I VAE++ T + + TL+ YPDIR DHI A+LA
Sbjct: 613 DTFQ----GLGSEATWLDQAIQCVAEILGETYKDDIQRHLETLIRSYPDIRRDHILAILA 668
Query: 699 VRGDASRDMKQTIMET--LEQGPAQASPSYVP----LFKDIVVPS 737
+R + + + T L + A A+ + P LF++I VPS
Sbjct: 669 LRRLGRQRNQHLLQHTQDLLRAAAGAAGAEAPRGRVLFEEIKVPS 713
>gi|26051240 tumor necrosis factor, alpha-induced protein 2 [Homo
sapiens]
Length = 654
Score = 145 bits (365), Expect = 2e-34
Identities = 141/619 (22%), Positives = 270/619 (43%), Gaps = 47/619 (7%)
Query: 123 PEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGSTQG 182
P V E + +E+G L +A R L+ LE +G + L+ +
Sbjct: 76 PPTVEELKAALERGQL-EAARPLLALERELAAAAA------AGGVSEEELVRRQ-SKVEA 127
Query: 183 LSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGRPK 242
L + L Q+ VL+R L P L + ++ +E+ DR+ T + RP+
Sbjct: 128 LYELLRDQVLGVLRRPL---EAPPERLRQALAVVAEQEREDRQAAAAGPGTSGLAATRPR 184
Query: 243 NWKEKMFTILERTVTTRI---EGTQADTRESDKMWLVRHLEIIRKYVLDDLIVAKNLMVQ 299
W + + R+ A+ ES + L R ++ +DL +
Sbjct: 185 RWLQLWRRGVAEAAEERMGQRPAAGAEVPESVFLHLGRTMK-------EDLEAVVERLKP 237
Query: 300 CFPPHYEIFKNLLNMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSTEMMRNVELA 359
FP + + YHQ + + +A +L + LL WV N Y + +++ + +L
Sbjct: 238 LFPAEFGVVAAYAESYHQHFAAHLAAVAQFELCERDTYMLLLWVQNLYPN-DIINSPKLV 296
Query: 360 PEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKETEPEADQDGY 419
E+ L LL P + L T++S+ +N+ + +ALE + + W ++ P+ DG+
Sbjct: 297 GELQGMGLGSLLPPRQIRLLEATFLSSEAANVRELMDRALELEARRWAEDVPPQR-LDGH 355
Query: 420 YQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRN 479
+ L + Q+ Q A I+ DL +++ + L ++ +FL Y+ + + E R
Sbjct: 356 CHSELAIDIIQITSQAQAKAESITLDLGSQIKRVLLVELPAFLRSYQ---RAFNEFLERG 412
Query: 480 RQHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEEGVSPSQPSMD---GILDAIAK 536
+Q + Y +IA INNC +F+ S+ E+ Q ++ G L +
Sbjct: 413 KQLTN-YRANVIANINNCLSFRMSM------------EQNWQVPQDTLSLLLGPLGELKS 459
Query: 537 EGCSGLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTA 596
G LL+ + DL+ +W ++ I TV+ +F++++ +++ +
Sbjct: 460 HGFDTLLQNLHEDLKPLFKRFTHTRWAAPVETLENIIATVDTRLPEFSELQGCFREELME 519
Query: 597 EAHRRVVVEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLRFLFRKLASGFGEDVDGYC 656
H +V EY+ + + R+ ++ E++++ A ++ A+ ++ + G
Sbjct: 520 ALHLHLVKEYIIQLSKGRLVLKTAEQQQQLAGYILANADTIQHF----CTQHGSPATWLQ 575
Query: 657 DTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASRDMKQTIMETLE 716
+ +AE+I+L DPS + +EV+T + YPD H+ A+LA++G+ S + I L+
Sbjct: 576 PALPTLAEIIRLQDPSAIKIEVATYATCYPDFSKGHLSAILAIKGNLSNSEVKRIRSILD 635
Query: 717 QGPAQASPSYVPLFKDIVV 735
PS PLF I V
Sbjct: 636 VSMGAQEPSR-PLFSLIKV 653
>gi|226371708 exocyst complex component 3-like 2 [Homo sapiens]
Length = 409
Score = 133 bits (335), Expect = 5e-31
Identities = 106/380 (27%), Positives = 182/380 (47%), Gaps = 28/380 (7%)
Query: 365 GTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVK-ETEPEADQDGYYQTT 423
G L PLLSP + L D ++ + + A L + L+ D++ W E +P ++
Sbjct: 7 GELGPLLSPGTLRGLEDECVTDVKAQTRAALLRVLQEDEEHWGSLEDQP---------SS 57
Query: 424 LPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRNRQHP 483
L V ++ E++ + A +IS++ ++ CL + FL ++ + + E P
Sbjct: 58 LAQDVCELLEEHTERAPRISQEFGERMAHCCLGGLAEFLQSFQQRVERFHENPAVREMLP 117
Query: 484 HCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEEGVSPSQPSMDGILDAIAKEGCSGLL 543
Y+ IA++N C ++ + E E P++ + LD + + +
Sbjct: 118 DTYISKTIALVN-CGPPLRALAERLARVGPPESE----PAREASASALDHVTRLCHRVVA 172
Query: 544 EEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVV 603
+F +L+ H N+LM +KWL A+D I T+ +++ + + AE HRR +
Sbjct: 173 NLLFQELQPHFNKLMRRKWLSSPEALDGIVGTLGAQALALRRMQDEPYQALVAELHRRAL 232
Query: 604 VEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLRFLFRKLASGFGEDVDGYCDTIVA-V 662
VEY+R +++ R+ S R A ++ +A QL+ LFR+L E + D +V +
Sbjct: 233 VEYVRPLLRGRLRCSSARTRSRVAGRLREDAAQLQRLFRRL-----ESQASWLDAVVPHL 287
Query: 663 AEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASRDMKQTI------METLE 716
AEV++L D + +EV LV YPDIR H+ ALL +RG + +Q I +E E
Sbjct: 288 AEVMQLEDTPSIQVEVGVLVRDYPDIRQKHVAALLDIRGLRNTAARQEILAVARDLELSE 347
Query: 717 QGPAQASPSYVPLFKDIVVP 736
+G A + P F DI VP
Sbjct: 348 EG-ALSPPRDRAFFADIPVP 366
>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
sapiens]
Length = 2155
Score = 45.1 bits (105), Expect = 2e-04
Identities = 96/481 (19%), Positives = 190/481 (39%), Gaps = 60/481 (12%)
Query: 2 KETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTG 61
K T E A++ LQ+ + +K+E +A+ ++ +RL A I + ++T
Sbjct: 984 KLTGMERDLVAIEAKLSDLQK--EAEKLESEHPDQAQ---AILSRL-AEISDVWEEMKTT 1037
Query: 62 LSQLHNALNDVKDIQQSLADVS--KDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNI 119
L +L + +QQ L D+ + W T + +D+ + + + +L EN+KN
Sbjct: 1038 LKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNE 1097
Query: 120 FSVPE----IVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHG 175
E +R+ +++ QG + L + D E ++M ++ H
Sbjct: 1098 IDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHA 1157
Query: 176 YFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRI-LDRKKQTG 234
Y Q L D + ++ Q ++ PT L I+++E + + +K
Sbjct: 1158 Y---QQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINA 1214
Query: 235 FVPPGR---------PKNWKEKMFTILERTVTTRIEGTQADTRESDKMWLVRHLEIIRK- 284
V GR +EK+ +I +R R ++ R D L + L+ ++
Sbjct: 1215 VVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQEL 1274
Query: 285 --YVLDDLIVAKNLMVQCFPPHYEIFKNLLNMY--HQALSTRMQDLASEDLEANEIVSLL 340
++ + ++ A+++ Y+ +NL + + HQA M +LAS ++I
Sbjct: 1275 SLWINEKMLTAQDM-------SYDEARNLHSKWLKHQAF---MAELASNKEWLDKI---- 1320
Query: 341 TWVLNTYTSTEMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALE 400
E M+ + PE + E L H + E+L++ T + + L
Sbjct: 1321 --------EKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELF 1372
Query: 401 T----DKKDWVKETEPEADQDGYYQTTLPAIVF----QMFEQNLQVAAQISEDLKTKVLV 452
T D W+ E + D Y + + QM E ++V + E+L+++
Sbjct: 1373 TQSCADLDKWLHGLESQIQSDDYGKDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQA 1432
Query: 453 L 453
L
Sbjct: 1433 L 1433
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 45.1 bits (105), Expect = 2e-04
Identities = 96/481 (19%), Positives = 190/481 (39%), Gaps = 60/481 (12%)
Query: 2 KETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTG 61
K T E A++ LQ+ + +K+E +A+ ++ +RL A I + ++T
Sbjct: 997 KLTGMERDLVAIEAKLSDLQK--EAEKLESEHPDQAQ---AILSRL-AEISDVWEEMKTT 1050
Query: 62 LSQLHNALNDVKDIQQSLADVS--KDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNI 119
L +L + +QQ L D+ + W T + +D+ + + + +L EN+KN
Sbjct: 1051 LKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNE 1110
Query: 120 FSVPE----IVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHG 175
E +R+ +++ QG + L + D E ++M ++ H
Sbjct: 1111 IDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHA 1170
Query: 176 YFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRI-LDRKKQTG 234
Y Q L D + ++ Q ++ PT L I+++E + + +K
Sbjct: 1171 Y---QQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINA 1227
Query: 235 FVPPGR---------PKNWKEKMFTILERTVTTRIEGTQADTRESDKMWLVRHLEIIRK- 284
V GR +EK+ +I +R R ++ R D L + L+ ++
Sbjct: 1228 VVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQEL 1287
Query: 285 --YVLDDLIVAKNLMVQCFPPHYEIFKNLLNMY--HQALSTRMQDLASEDLEANEIVSLL 340
++ + ++ A+++ Y+ +NL + + HQA M +LAS ++I
Sbjct: 1288 SLWINEKMLTAQDM-------SYDEARNLHSKWLKHQAF---MAELASNKEWLDKI---- 1333
Query: 341 TWVLNTYTSTEMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALE 400
E M+ + PE + E L H + E+L++ T + + L
Sbjct: 1334 --------EKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELF 1385
Query: 401 T----DKKDWVKETEPEADQDGYYQTTLPAIVF----QMFEQNLQVAAQISEDLKTKVLV 452
T D W+ E + D Y + + QM E ++V + E+L+++
Sbjct: 1386 TQSCADLDKWLHGLESQIQSDDYGKDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQA 1445
Query: 453 L 453
L
Sbjct: 1446 L 1446
>gi|212276078 leucine rich repeat (in FLII) interacting protein 1
isoform 1 [Homo sapiens]
Length = 640
Score = 40.4 bits (93), Expect = 0.006
Identities = 46/215 (21%), Positives = 87/215 (40%), Gaps = 32/215 (14%)
Query: 19 MLQRPDQL-DKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQ 77
+L+ +QL + QY E K+ E + +Q Q V+ L Q L +++ +QQ
Sbjct: 327 LLELEEQLAESRRQYE--EKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEEIRQLQQ 384
Query: 78 SLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQGA 137
A ++I + D+++ + + A+E K F + E DL E+
Sbjct: 385 KQA----------SSIREISDLQETIEWKDKKIGALERQKEFFD--SVRSERDDLREEVV 432
Query: 138 LLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGSTQGLSDELAKQLWMVLQR 197
+L+ E + G++ +G T D GY G T+ +EL
Sbjct: 433 MLKE-------ELKKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEEL---------- 475
Query: 198 SLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQ 232
+ + D TL + + ++++ E + +I K Q
Sbjct: 476 NALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQ 510
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 38.5 bits (88), Expect = 0.023
Identities = 42/226 (18%), Positives = 104/226 (46%), Gaps = 15/226 (6%)
Query: 7 EAVATAVQRVAGMLQRPDQLDKVEQYRRREARK-KASVEARLKAAIQSQLDGVRTGLSQL 65
E + ++ V + Q D L ++++ + E + K+ + + I +Q QL
Sbjct: 915 EKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQ--------EQL 966
Query: 66 HNALNDVKDIQQSL----ADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENL--KNI 119
NAL +K Q+++ + +S++ ++++ E+ + KD Q ++L KN
Sbjct: 967 RNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNT 1026
Query: 120 FSVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGS 179
++ V++ + + +Q + ++ +L+ + ++ E+ ++ + ++ +
Sbjct: 1027 QTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEE 1086
Query: 180 TQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRR 225
+ L DEL KQ +V Q ++++ L + R+ E EEK+ +
Sbjct: 1087 LRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEK 1132
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 37.0 bits (84), Expect = 0.067
Identities = 46/226 (20%), Positives = 101/226 (44%), Gaps = 23/226 (10%)
Query: 1 MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKK-------ASVEARLKAAIQS 53
M++T E A +Q + L+R ++ ++ QYR R+A +K ++ L +++
Sbjct: 380 MRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQ 439
Query: 54 QLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKD-VKDAVVQHSQLAAA 112
L + +LH+ L +V++ + + D ++ RQ + +E K +++ + + +L+
Sbjct: 440 DLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLK 499
Query: 113 VENLKNIFSVPEIVRET-------------QDLIEQGALLQAHRKLMDLECSRDGLMYEQ 159
K++ + ++T Q + E+ AL++ +D E R ++
Sbjct: 500 RRGSKDLPKSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQK 559
Query: 160 YRMDSGNTRDMTLIHGYFGSTQGLSD-ELAKQLWMVLQRSLVTVRR 204
YR G+ D L G G + EL +L +V + + + R+
Sbjct: 560 YRSFYGDL-DSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRK 604
>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 36.2 bits (82), Expect = 0.11
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Query: 48 KAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHS 107
KAA+Q QL+ VR L QL A+ V I Q L + + I+ + +D++ A+ Q
Sbjct: 159 KAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISA--AFEDLEQALQQRK 216
Query: 108 QLAAAVENLKNIFSVPEIVRETQ-DLIEQG 136
Q A V +L+ I + V ++Q D + QG
Sbjct: 217 Q--ALVSDLETICGAKQKVLQSQLDTLRQG 244
>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 36.2 bits (82), Expect = 0.11
Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Query: 48 KAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHS 107
KAA+Q QL+ VR L QL A+ V I Q L + + I+ + +D++ A+ Q
Sbjct: 159 KAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISA--AFEDLEQALQQRK 216
Query: 108 QLAAAVENLKNIFSVPEIVRETQ-DLIEQG 136
Q A V +L+ I + V ++Q D + QG
Sbjct: 217 Q--ALVSDLETICGAKQKVLQSQLDTLRQG 244
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 35.8 bits (81), Expect = 0.15
Identities = 36/146 (24%), Positives = 59/146 (40%), Gaps = 19/146 (13%)
Query: 48 KAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHS 107
++ +Q++ D R+ L++ L +D+Q+S+ + + WR + E V+H
Sbjct: 688 QSTLQAECDQYRSILAETEGML---RDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKH- 743
Query: 108 QLAAAVENLKNIFSVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNT 167
L VE LK + VRE +E A L+ H EC + Y +
Sbjct: 744 -LEEIVEKLKGELESSDQVREHTSHLE--AELEKHMAAASAEC-------QNYAKEVAGL 793
Query: 168 RDMTL-----IHGYFGSTQGLSDELA 188
R + L + Q SDELA
Sbjct: 794 RQLLLESQSQLDAAKSEAQKQSDELA 819
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 35.8 bits (81), Expect = 0.15
Identities = 36/146 (24%), Positives = 59/146 (40%), Gaps = 19/146 (13%)
Query: 48 KAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHS 107
++ +Q++ D R+ L++ L +D+Q+S+ + + WR + E V+H
Sbjct: 688 QSTLQAECDQYRSILAETEGML---RDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKH- 743
Query: 108 QLAAAVENLKNIFSVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNT 167
L VE LK + VRE +E A L+ H EC + Y +
Sbjct: 744 -LEEIVEKLKGELESSDQVREHTSHLE--AELEKHMAAASAEC-------QNYAKEVAGL 793
Query: 168 RDMTL-----IHGYFGSTQGLSDELA 188
R + L + Q SDELA
Sbjct: 794 RQLLLESQSQLDAAKSEAQKQSDELA 819
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 35.0 bits (79), Expect = 0.25
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 16/135 (11%)
Query: 2 KETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARL----KAAIQSQLDG 57
+ T+ + + Q+V +L D+ + + +E RKK + EA+L KA + SQ
Sbjct: 66 ENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQ 125
Query: 58 VRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLK 117
+ T +L A ++ +QQ A++ + ++ES K + + QH Q ++ +
Sbjct: 126 ISTYEEELAKAREELSRLQQETAELEE-------SVESGKAQLEPLQQHLQ-----DSQQ 173
Query: 118 NIFSVPEIVRETQDL 132
I S+ + E +DL
Sbjct: 174 EISSMQMKLMEMKDL 188
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 35.0 bits (79), Expect = 0.25
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 16/135 (11%)
Query: 2 KETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARL----KAAIQSQLDG 57
+ T+ + + Q+V +L D+ + + +E RKK + EA+L KA + SQ
Sbjct: 380 ENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQ 439
Query: 58 VRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLK 117
+ T +L A ++ +QQ A++ + ++ES K + + QH Q ++ +
Sbjct: 440 ISTYEEELAKAREELSRLQQETAELEE-------SVESGKAQLEPLQQHLQ-----DSQQ 487
Query: 118 NIFSVPEIVRETQDL 132
I S+ + E +DL
Sbjct: 488 EISSMQMKLMEMKDL 502
Score = 30.0 bits (66), Expect = 8.1
Identities = 23/109 (21%), Positives = 55/109 (50%), Gaps = 11/109 (10%)
Query: 60 TGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIE----SLKDVKDAVVQHSQLAAAVEN 115
+ + +L N++ D+Q+ +V +D ++ +TI+ ++D++D V + + N
Sbjct: 330 SAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQREN------TN 383
Query: 116 LKNIFSVPEIVRETQD-LIEQGALLQAHRKLMDLECSRDGLMYEQYRMD 163
L+ + + + V+E D L EQ A L+ K + +C+ + + + +
Sbjct: 384 LQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAE 432
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 34.3 bits (77), Expect = 0.43
Identities = 104/546 (19%), Positives = 214/546 (39%), Gaps = 63/546 (11%)
Query: 1 MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARL---KAAIQSQLDG 57
+K+T+ E++++ + V + R +++ + + + K +EA++ K Q Q+D
Sbjct: 681 VKQTELESLSSELSEV--LKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDS 738
Query: 58 V----RTGLSQLHNALND-VKDIQQSLADVSKDWRQSINTIESLK-DVKDAVVQHSQLAA 111
+ + + AL D + ++ L + K ++ +E+L+ D+K + + Q +A
Sbjct: 739 IIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASA 798
Query: 112 AVENLKNIFSVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMT 171
++ +F + Q + L Q +KL+DLE R L + +++ T
Sbjct: 799 KLD----VFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCT 854
Query: 172 LIHGYFGSTQGLSDELAKQ----------LWMVLQRSLVTVRRDPTLLVSVVRIIEREEK 221
+ + Q L +L KQ L V + L ++ + ++E+E
Sbjct: 855 ELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI--LVEKENM 912
Query: 222 IDRRILDRKKQTGFVPPGRPKNWKEKMFTILERTVTTRIEGTQADTRESDKMWLVRHLEI 281
I + +KK+ + + + KE IL T+ + Q E K E
Sbjct: 913 ILQMREGQKKEIEILT--QKLSAKEDSIHILNEEYETKFK-NQEKKMEKVKQKAKEMQET 969
Query: 282 IRKYVLDDLIVAK----NLMVQCFPPHYEIFKNLLNMYHQALSTRMQDLASEDLEANEIV 337
++K +LD K N ++ + +L M QA S + D S LE N+
Sbjct: 970 LKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEM-AQANSAGISDAVSR-LETNQKE 1027
Query: 338 SLLTWVLNTYTSTEMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRK 397
+ + TE+ R EL + + + + E+ + + + +K
Sbjct: 1028 QI-------ESLTEVHRR-ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQK 1079
Query: 398 AL--ETDKKDWVKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCL 455
L +K++ KE ++ TTL + Q+ +++ V + ++ K K + L
Sbjct: 1080 ILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKL 1139
Query: 456 Q-------QMNSFLSRYKDEAQLYKEEHLRNRQHPHCYVQYMIAIINNCQTFKESIVSLK 508
+ + N+FL E ++ EE R + + + +T E SLK
Sbjct: 1140 EVDLNKSLKENTFLQEQLVELKMLAEEDKRK----------VSELTSKLKTTDEEFQSLK 1189
Query: 509 RKYLKN 514
+ K+
Sbjct: 1190 SSHEKS 1195
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 33.9 bits (76), Expect = 0.56
Identities = 26/121 (21%), Positives = 55/121 (45%), Gaps = 15/121 (12%)
Query: 25 QLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQ----LHNALNDVKDIQQSLA 80
QL ++ + E R+K S+ +LK ++ + + R L + HN + + +A
Sbjct: 1309 QLQDTQELLQEENRQKLSLSTKLKQ-VEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVA 1367
Query: 81 DVSKDWRQSINTIESLKDVKDAV--------VQHSQLAAAVENLKNIFSVPEIVRETQDL 132
D+ K S+ +E+ ++VK + +H + AA + L+ + + +E DL
Sbjct: 1368 DMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEK--TKTRLQQELDDL 1425
Query: 133 I 133
+
Sbjct: 1426 L 1426
>gi|18641360 collectin sub-family member 12 [Homo sapiens]
Length = 742
Score = 33.5 bits (75), Expect = 0.74
Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 5/104 (4%)
Query: 29 VEQYRRREARKKASVEARLKA-AIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWR 87
+E R+ K +VE+ LK Q+ + T S+L +D+ D++Q L ++++
Sbjct: 72 METSRQTYDDKLTAVESDLKKLGDQTGKKAISTN-SELSTFRSDILDLRQQLREITEKTS 130
Query: 88 QSINTIESLKDVKDAVV-QHSQLAAAVENLKNIFSVPEIVRETQ 130
++ +T+E L+ DA+V + SQL +EN N F + + + Q
Sbjct: 131 KNKDTLEKLQASGDALVDRQSQLKETLEN--NSFLITTVNKTLQ 172
>gi|7662230 ring finger protein 40 [Homo sapiens]
Length = 1001
Score = 33.5 bits (75), Expect = 0.74
Identities = 38/162 (23%), Positives = 71/162 (43%), Gaps = 5/162 (3%)
Query: 5 DREAVATAVQRVAGMLQRPD-QLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLS 63
+RE + VA L R D + KVE+ +R+E+ + A LK A +SQ + ++ L
Sbjct: 616 EREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGLRAELKKAQESQKE-MKLLLD 674
Query: 64 QLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVP 123
+A + +D Q +A K + ++++++ + S+ A + L+ I
Sbjct: 675 MYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAE 734
Query: 124 EIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSG 165
E + Q + GA Q L+ E G +E + +G
Sbjct: 735 EQIEHLQRKL--GATKQEEEALLS-EMDVTGQAFEDMQEQNG 773
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 33.1 bits (74), Expect = 0.96
Identities = 28/112 (25%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 2 KETDREAVATAVQRVAGMLQRPD-QLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRT 60
K+ D+ + A+ V+ + ++ D ++ VE+ E K A+ E ++ +I S++ ++
Sbjct: 785 KQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQELQN 844
Query: 61 GLSQLHNALNDVKDI----QQSLADVSKDWRQSINTI-ESLKDVKDAVVQHS 107
L +N +K + ++ LA+ K W Q + ESLK V QH+
Sbjct: 845 LLKGKEEQMNTMKAVLEEKEKDLANTGK-WLQDLQEENESLKAHVQEVAQHN 895
>gi|169169865 PREDICTED: hypothetical protein LOC285754 [Homo
sapiens]
Length = 1151
Score = 33.1 bits (74), Expect = 0.96
Identities = 30/139 (21%), Positives = 53/139 (38%), Gaps = 13/139 (9%)
Query: 300 CFPPHYEIFKNLLNMYHQALSTRMQDLASED---------LEANEIVSLLTWVLNTYTST 350
C H ++ + +LN + +Q L ED L N + L + N+ ++
Sbjct: 758 CLRLHLQLVRGILNQQIERQREYVQRLWREDHLDNSNTFGLPLNIVCKQLISINNSCPAS 817
Query: 351 EMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKET 410
+ + +E P + + L P H+ E T S + + R L+ W+
Sbjct: 818 KNVYLLEFHPSLSLAALIPKALEHLFQEACHACRPTSASGLASLERHVLQLALDLWLTPA 877
Query: 411 EPEADQDGYYQTTLPAIVF 429
PEA +Y T L +F
Sbjct: 878 TPEA----WYSTQLQKDLF 892
>gi|169168870 PREDICTED: hypothetical protein LOC285754 [Homo
sapiens]
Length = 1151
Score = 33.1 bits (74), Expect = 0.96
Identities = 30/139 (21%), Positives = 53/139 (38%), Gaps = 13/139 (9%)
Query: 300 CFPPHYEIFKNLLNMYHQALSTRMQDLASED---------LEANEIVSLLTWVLNTYTST 350
C H ++ + +LN + +Q L ED L N + L + N+ ++
Sbjct: 758 CLRLHLQLVRGILNQQIERQREYVQRLWREDHLDNSNTFGLPLNIVCKQLISINNSCPAS 817
Query: 351 EMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKET 410
+ + +E P + + L P H+ E T S + + R L+ W+
Sbjct: 818 KNVYLLEFHPSLSLAALIPKALEHLFQEACHACRPTSASGLASLERHVLQLALDLWLTPA 877
Query: 411 EPEADQDGYYQTTLPAIVF 429
PEA +Y T L +F
Sbjct: 878 TPEA----WYSTQLQKDLF 892
>gi|169169319 PREDICTED: hypothetical protein LOC285754 [Homo
sapiens]
Length = 1151
Score = 33.1 bits (74), Expect = 0.96
Identities = 30/139 (21%), Positives = 53/139 (38%), Gaps = 13/139 (9%)
Query: 300 CFPPHYEIFKNLLNMYHQALSTRMQDLASED---------LEANEIVSLLTWVLNTYTST 350
C H ++ + +LN + +Q L ED L N + L + N+ ++
Sbjct: 758 CLRLHLQLVRGILNQQIERQREYVQRLWREDHLDNSNTFGLPLNIVCKQLISINNSCPAS 817
Query: 351 EMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKET 410
+ + +E P + + L P H+ E T S + + R L+ W+
Sbjct: 818 KNVYLLEFHPSLSLAALIPKALEHLFQEACHACRPTSASGLASLERHVLQLALDLWLTPA 877
Query: 411 EPEADQDGYYQTTLPAIVF 429
PEA +Y T L +F
Sbjct: 878 TPEA----WYSTQLQKDLF 892
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 33.1 bits (74), Expect = 0.96
Identities = 35/209 (16%), Positives = 96/209 (45%), Gaps = 23/209 (11%)
Query: 25 QLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSK 84
+L + E+ K AS+E + K +Q +++ + L + H A + Q++ V
Sbjct: 1400 RLQEAEENTETANSKCASLE-KTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLA 1458
Query: 85 DWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQGALLQAHRK 144
+W+Q ++ ES +++ A + L+ + ++N + +++++Q L+ K
Sbjct: 1459 EWKQKLD--ESQAELEAAQKESRSLSTELFKMRNAY---------EEVVDQLETLRRENK 1507
Query: 145 LMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRR 204
+ E S + EQ N ++ T+ L ++ L + L+ ++
Sbjct: 1508 NLQEEISD---LTEQIAETGKNLQEAE-------KTKKLVEQEKSDLQVALEEVEGSLEH 1557
Query: 205 DPTLLVSV-VRIIEREEKIDRRILDRKKQ 232
+ + ++ V + + + + ++DR+++++ ++
Sbjct: 1558 EESKILRVQLELSQVKSELDRKVIEKDEE 1586
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 33.1 bits (74), Expect = 0.96
Identities = 26/135 (19%), Positives = 58/135 (42%), Gaps = 5/135 (3%)
Query: 35 REARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIE 94
R+ + V+ R +Q +++ ++ L L ++KD +SL S + ++ T+E
Sbjct: 528 RDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLE 587
Query: 95 SLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIE-----QGALLQAHRKLMDLE 149
K+ +++ + ++ + + + +E +DL E Q L + L+DL+
Sbjct: 588 EALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLK 647
Query: 150 CSRDGLMYEQYRMDS 164
L + DS
Sbjct: 648 EHASSLASAGLKRDS 662
>gi|21264345 peripherin [Homo sapiens]
Length = 470
Score = 33.1 bits (74), Expect = 0.96
Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 9/96 (9%)
Query: 21 QRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLA 80
Q P + D++ Q RE R++ + R + +Q + DG+ L+ L L +
Sbjct: 135 QEPARADQLCQQELRELRRELELLGRERDRVQVERDGLAEDLAALKQRLEE--------- 185
Query: 81 DVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENL 116
+ K N + KDV DA + +L +E+L
Sbjct: 186 ETRKREDAEHNLVLFRKDVDDATLSRLELERKIESL 221
>gi|21614525 glypican 4 [Homo sapiens]
Length = 556
Score = 33.1 bits (74), Expect = 0.96
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 433 EQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKE--EHLRNRQHPHCYVQYM 490
E + + Q +D K+ V C F SRYK + +KE E+ + Y
Sbjct: 70 EMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYG 129
Query: 491 IAIINNCQTFKESIVSLKRKYLKNEV 516
+ N + FK+ V LKR Y+ V
Sbjct: 130 HLYMQNSELFKDLFVELKRYYVVGNV 155
>gi|62243374 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 32.7 bits (73), Expect = 1.3
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 11/98 (11%)
Query: 48 KAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHS 107
K +Q QLD + + + +++ Q++ AD + +KD++ +
Sbjct: 187 KQELQEQLDLQHKKCQEANQKIQELQASQEARADHE----------QQIKDLEQKLSLQE 236
Query: 108 QLAAAVENLKN-IFSVPEIVRETQDLIEQGALLQAHRK 144
Q AA V+N+K+ + +P + RE + L E+ A L+ R+
Sbjct: 237 QDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRE 274
>gi|62243369 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 32.7 bits (73), Expect = 1.3
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 11/98 (11%)
Query: 48 KAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHS 107
K +Q QLD + + + +++ Q++ AD + +KD++ +
Sbjct: 187 KQELQEQLDLQHKKCQEANQKIQELQASQEARADHE----------QQIKDLEQKLSLQE 236
Query: 108 QLAAAVENLKN-IFSVPEIVRETQDLIEQGALLQAHRK 144
Q AA V+N+K+ + +P + RE + L E+ A L+ R+
Sbjct: 237 QDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRE 274
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,012,157
Number of Sequences: 37866
Number of extensions: 1015985
Number of successful extensions: 3559
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 3467
Number of HSP's gapped (non-prelim): 149
length of query: 745
length of database: 18,247,518
effective HSP length: 110
effective length of query: 635
effective length of database: 14,082,258
effective search space: 8942233830
effective search space used: 8942233830
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.