Guide to the Human Genome
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Search of human proteins with 30911103

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30911103 pygopus homolog 1 [Homo sapiens]
         (419 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30911103 pygopus homolog 1 [Homo sapiens]                          897   0.0  
gi|23510333 pygopus homolog 2 [Homo sapiens]                          240   2e-63
gi|31543543 retinoic acid induced 17 [Homo sapiens]                    44   4e-04
gi|20162566 chromosome 7 open reading frame 11 [Homo sapiens]          43   5e-04
gi|241982780 programmed cell death 6 interacting protein isoform...    43   6e-04
gi|22027538 programmed cell death 6 interacting protein isoform ...    43   6e-04
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...    42   8e-04
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     42   0.001
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     42   0.001
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]      41   0.002
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    41   0.002
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    41   0.002
gi|38373671 SEC24-related protein C [Homo sapiens]                     41   0.002
gi|38373669 SEC24-related protein C [Homo sapiens]                     41   0.002
gi|11415052 retinoid X receptor, beta [Homo sapiens]                   40   0.003
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    40   0.003
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    40   0.003
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]                  40   0.003
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    40   0.003
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    40   0.004
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    40   0.004
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    40   0.004
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor...    40   0.004
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    40   0.004
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]       40   0.004
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       40   0.004
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       40   0.004
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        40   0.004
gi|57165375 glutamate receptor, ionotropic, N-methyl D-aspartate...    40   0.004
gi|57165373 glutamate receptor, ionotropic, N-methyl D-aspartate...    40   0.004

>gi|30911103 pygopus homolog 1 [Homo sapiens]
          Length = 419

 Score =  897 bits (2318), Expect = 0.0
 Identities = 419/419 (100%), Positives = 419/419 (100%)

Query: 1   MPAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPN 60
           MPAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPN
Sbjct: 1   MPAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPN 60

Query: 61  PNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCG 120
           PNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCG
Sbjct: 61  PNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCG 120

Query: 121 PYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNP 180
           PYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNP
Sbjct: 121 PYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNP 180

Query: 181 AENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQD 240
           AENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQD
Sbjct: 181 AENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQD 240

Query: 241 FTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPA 300
           FTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPA
Sbjct: 241 FTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPA 300

Query: 301 NGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCE 360
           NGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCE
Sbjct: 301 NGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCE 360

Query: 361 ASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA 419
           ASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA
Sbjct: 361 ASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA 419


>gi|23510333 pygopus homolog 2 [Homo sapiens]
          Length = 406

 Score =  240 bits (613), Expect = 2e-63
 Identities = 161/439 (36%), Positives = 214/439 (48%), Gaps = 58/439 (13%)

Query: 3   AENSPAPAYKVSSHGGDSGLDG-------LGGPGVQLGSPDKKKRKANTQGPSFPPLSEY 55
           A ++P P  K+   GG +            G  G+Q+ SP+KK+RK+NTQGP++  L+E+
Sbjct: 2   AASAPPPPDKLEGGGGPAPPPAPPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTEF 61

Query: 56  APPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFR-MPPHVPPRM 114
           APPP P  DHLVA+NPF+D++   + K   ++ P+LG   P FGG+     M   VPP  
Sbjct: 62  APPPTPMVDHLVASNPFEDDFG--APKVGVAAPPFLGSPVP-FGGFRVQGGMAGQVPPGY 118

Query: 115 SSPYCG-PYSLRNQPHPFPQNPLGMGFNRP-HAFNFGPHDNSSFGNPSYNNALSQNVNMP 172
           S+   G P  LR QP PFP NP+G  FN P     + P  N +F +  +N  L QN + P
Sbjct: 119 STGGGGGPQPLRRQPPPFPPNPMGPAFNMPPQGPGYPPPGNMNFPSQPFNQPLGQNFSPP 178

Query: 173 NQHFRQNPAENFSQI-------PPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIP- 224
           +      P   F  +       PP+  +++  P L+  F         SPL+     +P 
Sbjct: 179 SGQMMPGPVGGFGPMISPTMGQPPR--AELGPPSLSQRFAQPGAPFGPSPLQRPGQGLPS 236

Query: 225 -PPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVN 283
            PPNT     +P P  D         +     +PP                    + A  
Sbjct: 237 LPPNT-----SPFPGPDPGFPGPGGEDGGKPLNPP-------------------ASTAFP 272

Query: 284 QENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDP---- 339
           QE    S   A N N  +   N   +  G  DA +     K+       G S   P    
Sbjct: 273 QEPHSGSPAAAVNGNQPSFPPNSSGRGGGTPDANSLAPPGKAG------GGSGPQPPPGL 326

Query: 340 VYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADK 399
           VYPCG C +EVNDDQDAILCEASCQKWFHR CTGMTE+AYGLLT EASAVW CD C+  K
Sbjct: 327 VYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCLKTK 386

Query: 400 DVQLMRTRETFGPSAVGSD 418
           ++Q +  RE  G     +D
Sbjct: 387 EIQSVYIREGMGQLVAAND 405


>gi|31543543 retinoic acid induced 17 [Homo sapiens]
          Length = 1067

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 55/215 (25%), Positives = 81/215 (37%), Gaps = 31/215 (14%)

Query: 24  GLGGPGVQLGSPDKKKRKA-NTQGPSFPPLSEYAPPPNPNS---DHLVAANPFDDNYNTI 79
           G+ GP + +  P         T G   P   +  P P P S    ++    P + NY   
Sbjct: 359 GMSGPPMGMNQPRPPGISPFGTHGQRMP--QQTYPGPRPQSLPIQNIKRPYPGEPNYGNQ 416

Query: 80  SYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCGPYSLRNQPHP--FPQNPLG 137
            Y P  S  P     YP           P+ P  ++SP      + +QP    +P   + 
Sbjct: 417 QYGP-NSQFPTQPGQYPA----------PNPPRPLTSPNYPGQRMPSQPSSGQYPPPTVN 465

Query: 138 MG-FNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIP-PQNASQV 195
           MG + +P  FN     N++F   SY+N    NVN P    R  P  N+   P P N +  
Sbjct: 466 MGQYYKPEQFN---GQNNTFSGSSYSNYSQGNVNRPP---RPVPVANYPHSPVPGNPTPP 519

Query: 196 SNP--DLASNFVPGNNSN--FTSPLESNHSFIPPP 226
             P   +     P  +    F   ++ N S +PPP
Sbjct: 520 MTPGSSIPPYLSPSQDVKPPFPPDIKPNMSALPPP 554


>gi|20162566 chromosome 7 open reading frame 11 [Homo sapiens]
          Length = 179

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 10/119 (8%)

Query: 85  PSSNPYLGPGYPGFGGYSTFR-MPPHVPPRMSSPYCGPYSLRNQPHPFPQN-PLGMGFNR 142
           P + PY GPG  G+G  S+FR  P    PR  SP  G  S  + P   P++ P G   + 
Sbjct: 8   PPTPPYPGPGGGGWGSGSSFRGTPGGGGPRPPSPRDGYGSPHHTPPYGPRSRPYGSSHSP 67

Query: 143 PHAFNFGPHDNSSFGNPS---YNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNP 198
            H    G      FG+PS   Y  + S++     Q F  +P +   Q  PQ + + S P
Sbjct: 68  RHG---GSFPGGRFGSPSPGGYPGSYSRSPAGSQQQFGYSPGQ--QQTHPQGSPRTSTP 121


>gi|241982780 programmed cell death 6 interacting protein isoform 2
           [Homo sapiens]
          Length = 873

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 43/148 (29%), Positives = 53/148 (35%), Gaps = 21/148 (14%)

Query: 3   AENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPP-LSEYAPPPNP 61
           A + P PAY+ S  GG +       P      P K +  A    P  P   +  A  P+P
Sbjct: 724 APSIPTPAYQSSPAGGHAPTPPTPAPRTM--PPTKPQPPARPPPPVLPANRAPSATAPSP 781

Query: 62  NSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMP-------------P 108
                 A  P      T    P P +     P YPG+ GY    MP             P
Sbjct: 782 VGAGTAAPAPSQ----TPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMP 837

Query: 109 HVPPRMSSPYCGPYSLRNQP-HPFPQNP 135
           + P    SP   PY    QP +PFPQ P
Sbjct: 838 YPPVYHQSPGQAPYPGPQQPSYPFPQPP 865


>gi|22027538 programmed cell death 6 interacting protein isoform 1
           [Homo sapiens]
          Length = 868

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 43/148 (29%), Positives = 53/148 (35%), Gaps = 21/148 (14%)

Query: 3   AENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPP-LSEYAPPPNP 61
           A + P PAY+ S  GG +       P      P K +  A    P  P   +  A  P+P
Sbjct: 719 APSIPTPAYQSSPAGGHAPTPPTPAPRTM--PPTKPQPPARPPPPVLPANRAPSATAPSP 776

Query: 62  NSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMP-------------P 108
                 A  P      T    P P +     P YPG+ GY    MP             P
Sbjct: 777 VGAGTAAPAPSQ----TPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMP 832

Query: 109 HVPPRMSSPYCGPYSLRNQP-HPFPQNP 135
           + P    SP   PY    QP +PFPQ P
Sbjct: 833 YPPVYHQSPGQAPYPGPQQPSYPFPQPP 860


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 65/249 (26%), Positives = 93/249 (37%), Gaps = 41/249 (16%)

Query: 8    APAYKVSSHGGDSGLDGLGGPGVQLGS------PDKKKRKANTQGPSFPPLSEYAPPPNP 61
            APA  V +  G     G  GP  Q+G       P +++     Q  + PP     PPP P
Sbjct: 989  APASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPP---GVPPPGP 1045

Query: 62   NSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYS----TFRMPPHVPPRMSS- 116
            +       +PF +     S   +P + P  G G+PG  G +     F MPP  PP   S 
Sbjct: 1046 HGP-----SPFPNQQTPPSM--MPGAVP--GSGHPGVAGNAPLGLPFGMPPPPPPPAPSI 1096

Query: 117  -PYCGPYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDN--SSFGNPSYNNALSQNVNMPN 173
             P+       +   P P N  G   + P A    P  N   S  NP + N L     MP+
Sbjct: 1097 IPFGSLADSISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHPN-LPATTTMPS 1155

Query: 174  QHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPP----PNTF 229
                     +    P   ++   +P + +  V GN     SPL    + +PP    P+  
Sbjct: 1156 ---------SLPLGPGLGSAAAQSPAIVA-AVQGNLLPSASPLPDPGTPLPPDPTAPSPG 1205

Query: 230  GQAKAPPPK 238
                 PPP+
Sbjct: 1206 TVTPVPPPQ 1214


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 59/269 (21%), Positives = 94/269 (34%), Gaps = 17/269 (6%)

Query: 44  TQGPSFPPLSEYAPPPNPNSDHLVAANPFD-DNYNTISYKPLPSSNPYLGPGYPG--FGG 100
           + G    PL+   P P+   D +    P      N  S +  P S P  G GYPG  +G 
Sbjct: 366 SSGGGGQPLAR-TPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGS 424

Query: 101 YSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMG--FNRPHAFNFGPHDNSSFGN 158
            +  R P  +  R  S   G    +  P    Q P G G     P+     PH       
Sbjct: 425 QTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQ--Q 482

Query: 159 PSYNNALSQNVNMPNQHFRQNPAENFSQI---PPQNASQVSNPDLASNFVPGNNSNFTSP 215
           P Y+             ++Q P     Q+    P  + Q S P    +  P  +   T+ 
Sbjct: 483 PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTT- 541

Query: 216 LESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKN 275
               H    PP +  QA++P  +Q   Q A    +Q ++   P         Q+    + 
Sbjct: 542 --QQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS---QQTAYSQQR 596

Query: 276 VNRNNAVNQENSRSSSTEATNNNPANGTQ 304
                 ++Q++  S ++ A +   + G Q
Sbjct: 597 FPPPQELSQDSFGSQASSAPSMTSSKGGQ 625



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 60/283 (21%), Positives = 100/283 (35%), Gaps = 42/283 (14%)

Query: 38   KKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTI-SYKPLPSSNPYLGPGYP 96
            +KR + T  P + P        + N+  ++    ++ N +   S +  P S+P++  G  
Sbjct: 1200 QKRNSMTPNPGYQP--------SMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQG 1251

Query: 97   GFGG----YSTFRMPP----HVPPRMSSPYCGPYS-LRNQPHPFPQNPLGMGFNRPHAFN 147
              GG    YS    P      + PR   PY GPY  +R +P   P+  +  G  +P+   
Sbjct: 1252 PNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMP 1311

Query: 148  FGPHD---NSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNF 204
              P     + S   P       Q  +     F      + S  P Q  +         N+
Sbjct: 1312 SNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQ--QNY 1369

Query: 205  VPGNNSNFTSPLESNHS-FIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMD 263
                +  +  P + +       P + GQ +  P +Q       +  +Q  +A P      
Sbjct: 1370 KRPMDGTYGPPAKRHEGEMYSVPYSTGQGQ--PQQQQLPPAQPQPASQQQAAQPSP--QQ 1425

Query: 264  DTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNK 306
            D  NQ           NA       +++T AT   PA G QN+
Sbjct: 1426 DVYNQYG---------NAYP-----ATATAATERRPAGGPQNQ 1454



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 75/339 (22%), Positives = 106/339 (31%), Gaps = 50/339 (14%)

Query: 21  GLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTIS 80
           G  G  G G Q  +P   ++  + Q    PP S+  P   P++       P        S
Sbjct: 455 GQQGPSGYGQQGQTPYYNQQSPHPQQQQ-PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513

Query: 81  YKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMGF 140
            +P  S  P   P       Y + +      P+   PY  P +        PQ P     
Sbjct: 514 SQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA---- 569

Query: 141 NRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQ---IPPQNASQVSN 197
                             PS    LSQ    P    +Q+    +SQ    PPQ  SQ S 
Sbjct: 570 ------------------PS---TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608

Query: 198 PDLASN-----FVPGNNSNFTSPLESNHSFIP---------PPNTFGQAKAPPPKQDFTQ 243
              AS+        G   +    L+S  S +P         P  T G           + 
Sbjct: 609 GSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISS 668

Query: 244 GATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPANGT 303
              + +N   S   PH +              V    +V Q  S   S  A       G 
Sbjct: 669 SQGEQSNPAQSPFSPHTS-PHLPGIRGPSPSPVGSPASVAQSRSGPLSPAA-----VPGN 722

Query: 304 QNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYP 342
           Q  PR P G +D+      N+SS+  +R G+   +P  P
Sbjct: 723 QMPPRPPSGQSDSIMHPSMNQSSIAQDR-GYMQRNPQMP 760


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 59/269 (21%), Positives = 94/269 (34%), Gaps = 17/269 (6%)

Query: 44  TQGPSFPPLSEYAPPPNPNSDHLVAANPFD-DNYNTISYKPLPSSNPYLGPGYPG--FGG 100
           + G    PL+   P P+   D +    P      N  S +  P S P  G GYPG  +G 
Sbjct: 366 SSGGGGQPLAR-TPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGS 424

Query: 101 YSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMG--FNRPHAFNFGPHDNSSFGN 158
            +  R P  +  R  S   G    +  P    Q P G G     P+     PH       
Sbjct: 425 QTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQ--Q 482

Query: 159 PSYNNALSQNVNMPNQHFRQNPAENFSQI---PPQNASQVSNPDLASNFVPGNNSNFTSP 215
           P Y+             ++Q P     Q+    P  + Q S P    +  P  +   T+ 
Sbjct: 483 PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTT- 541

Query: 216 LESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKN 275
               H    PP +  QA++P  +Q   Q A    +Q ++   P         Q+    + 
Sbjct: 542 --QQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS---QQTAYSQQR 596

Query: 276 VNRNNAVNQENSRSSSTEATNNNPANGTQ 304
                 ++Q++  S ++ A +   + G Q
Sbjct: 597 FPPPQELSQDSFGSQASSAPSMTSSKGGQ 625



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 75/339 (22%), Positives = 106/339 (31%), Gaps = 50/339 (14%)

Query: 21  GLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTIS 80
           G  G  G G Q  +P   ++  + Q    PP S+  P   P++       P        S
Sbjct: 455 GQQGPSGYGQQGQTPYYNQQSPHPQQQQ-PPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513

Query: 81  YKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMGF 140
            +P  S  P   P       Y + +      P+   PY  P +        PQ P     
Sbjct: 514 SQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA---- 569

Query: 141 NRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQ---IPPQNASQVSN 197
                             PS    LSQ    P    +Q+    +SQ    PPQ  SQ S 
Sbjct: 570 ------------------PS---TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608

Query: 198 PDLASN-----FVPGNNSNFTSPLESNHSFIP---------PPNTFGQAKAPPPKQDFTQ 243
              AS+        G   +    L+S  S +P         P  T G           + 
Sbjct: 609 GSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISS 668

Query: 244 GATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPANGT 303
              + +N   S   PH +              V    +V Q  S   S  A       G 
Sbjct: 669 SQGEQSNPAQSPFSPHTS-PHLPGIRGPSPSPVGSPASVAQSRSGPLSPAA-----VPGN 722

Query: 304 QNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYP 342
           Q  PR P G +D+      N+SS+  +R G+   +P  P
Sbjct: 723 QMPPRPPSGQSDSIMHPSMNQSSIAQDR-GYMQRNPQMP 760


>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
          Length = 1544

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 13/38 (34%), Positives = 22/38 (57%)

Query: 338  DPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMT 375
            D + P   C     D+ D + C+ SC +WFH++C G++
Sbjct: 1484 DAICPAVSCLQPEGDEVDWVQCDGSCNQWFHQVCVGVS 1521


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 64/262 (24%), Positives = 91/262 (34%), Gaps = 43/262 (16%)

Query: 2    PAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKAN-------TQGPSFPPLSE 54
            P    P+P +  S+  G   L G   PG   G     + +A          GP+  P   
Sbjct: 768  PLHFPPSP-FPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPA 826

Query: 55   YAPP----PNPNSDHLVAANPFDDNYNTISYKPLPSSNP--YLGPGY-----PGFGGYST 103
            Y P     P  +  H V ++P+           LPS+ P  + GP       P      +
Sbjct: 827  YTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDS 886

Query: 104  FR--MPPHVPPRMSS-----PYCGPYSLRNQPHPFPQN-PLGMGFNRPHAFNFGPHDNSS 155
             +  +P H  PR +      P C P     QP P P   P G     P   +F     + 
Sbjct: 887  IQAPIPSHTAPRPNPTPAPPPPCFPVP-PPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAG 945

Query: 156  FGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSP 215
            F  P            P  H + +P++ F   PPQ    + +P L     PG       P
Sbjct: 946  FPAPRIGP-------QPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPG-----LLP 993

Query: 216  LESNHSFIPPPNTFGQAKAPPP 237
             +S + + P P   GQ   PPP
Sbjct: 994  PQSPYPYAPQPGVLGQ---PPP 1012


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo
           sapiens]
          Length = 1758

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 63/247 (25%), Positives = 96/247 (38%), Gaps = 40/247 (16%)

Query: 39  KRKANTQGPSFP--PLSEYAPPP--NPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPG 94
           +R   TQGPS P  P+    PPP   P   H +   P           P P  +P   PG
Sbjct: 540 ERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPP---------GVPPPQFSPQFPPG 590

Query: 95  YPGFGGYSTFRMPPHVPP---RMSSPY--CGPYSLRNQPHPFPQNP------LGMGFNRP 143
            P   GYS    PP  PP    +S+P+   G  +  +   P  Q P            R 
Sbjct: 591 QPPPAGYSV--PPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRL 648

Query: 144 HAFNFGPHDNSSFGNPSYNNALSQNVNMP----NQHFRQNPAENFSQIPP---QNASQVS 196
              +  P+  SS+   SY  + S++ +      ++ F ++ + ++S+ PP   +   +  
Sbjct: 649 KEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSR 708

Query: 197 NPDLASNFVPGNNSNFTS-PLESNHSFIPPPNTF-GQAKAPPPKQDFTQGATKNT--NQN 252
           N    S     + S   S P    HS    P  F GQ+   P K++  QG T+    N+ 
Sbjct: 709 NYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQS---PNKRNVPQGETEREYFNRY 765

Query: 253 SSAHPPH 259
               PP+
Sbjct: 766 REVPPPY 772



 Score = 32.7 bits (73), Expect = 0.63
 Identities = 33/137 (24%), Positives = 57/137 (41%), Gaps = 9/137 (6%)

Query: 206  PGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHL-NMDD 264
            P    N T P     S +   N  G  K+        + + K+ +  +S++     N D 
Sbjct: 1382 PEKRKNSTQP--EKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDK 1439

Query: 265  TVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNK 324
              +    E  +  R +  N E +R   + + N + A+G +NKPR+ R      T + S K
Sbjct: 1440 KTDYDTREYSSSKRRDEKN-ELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGD-SKK 1497

Query: 325  SSLHPNR----HGHSSS 337
            S+  P+R    H H ++
Sbjct: 1498 SNSSPSRDRKPHDHKAT 1514


>gi|38373671 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 70/272 (25%), Positives = 93/272 (34%), Gaps = 27/272 (9%)

Query: 9   PAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPN----PNSD 64
           P Y  SS+GG SG      P      P    ++   QG S  P S  APP +    P   
Sbjct: 21  PGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQ 80

Query: 65  HLVAANPFDDNYN----TISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCG 120
                    D  N    T+  + LP S P+  P  P   G     + P+ PP  S+    
Sbjct: 81  AAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAP--VGNQPPVLQPYGPPPTSAQVAT 138

Query: 121 PYS---LRNQPHPFPQNPLGMGFNRPH--AFNFGPHDNSS-FGNPSYNNA--LSQNVNMP 172
             S   +     P P +  G+GF  P   A   G   NS  +G+     A  LSQ    P
Sbjct: 139 QLSGMQISGAVAPAPPSS-GLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHP 197

Query: 173 NQHF--RQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNH-----SFIPP 225
                 R  P++  S  PP +      P +    +PG +    S  + NH       +PP
Sbjct: 198 GIQTPQRSAPSQASSFTPPASGGP-RLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPP 256

Query: 226 PNTFGQAKAPPPKQDFTQGATKNTNQNSSAHP 257
                    P P     Q       QN S  P
Sbjct: 257 GTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGP 288


>gi|38373669 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 70/272 (25%), Positives = 93/272 (34%), Gaps = 27/272 (9%)

Query: 9   PAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPN----PNSD 64
           P Y  SS+GG SG      P      P    ++   QG S  P S  APP +    P   
Sbjct: 21  PGYHQSSYGGQSGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQ 80

Query: 65  HLVAANPFDDNYN----TISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCG 120
                    D  N    T+  + LP S P+  P  P   G     + P+ PP  S+    
Sbjct: 81  AAYGQFGQGDVQNGPSSTVQMQRLPGSQPFGSPLAP--VGNQPPVLQPYGPPPTSAQVAT 138

Query: 121 PYS---LRNQPHPFPQNPLGMGFNRPH--AFNFGPHDNSS-FGNPSYNNA--LSQNVNMP 172
             S   +     P P +  G+GF  P   A   G   NS  +G+     A  LSQ    P
Sbjct: 139 QLSGMQISGAVAPAPPSS-GLGFGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHP 197

Query: 173 NQHF--RQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNH-----SFIPP 225
                 R  P++  S  PP +      P +    +PG +    S  + NH       +PP
Sbjct: 198 GIQTPQRSAPSQASSFTPPASGGP-RLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPP 256

Query: 226 PNTFGQAKAPPPKQDFTQGATKNTNQNSSAHP 257
                    P P     Q       QN S  P
Sbjct: 257 GTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGP 288


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 40/155 (25%), Positives = 54/155 (34%), Gaps = 38/155 (24%)

Query: 18  GDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYN 77
           G++G DG+G  G    SPD              PL +  PPP+P                
Sbjct: 66  GEAGRDGMGDSGRDSRSPDSSSPN---------PLPQGVPPPSPPGP------------- 103

Query: 78  TISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLG 137
                PLP S        P  GG      PP  PP + SP+  P    +   P    P  
Sbjct: 104 -----PLPPSTA------PSLGGSGAPPPPPMPPPPLGSPF--PVISSSMGSPGLPPPAP 150

Query: 138 MGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMP 172
            GF+ P +    P  NS+   P   +   ++V  P
Sbjct: 151 PGFSGPVS---SPQINSTVSLPGGGSGPPEDVKPP 182


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 56/234 (23%), Positives = 88/234 (37%), Gaps = 38/234 (16%)

Query: 28  PGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSS 87
           PG + G P+ ++ +     P      +  PPP P++   + ++P +     +   P   S
Sbjct: 155 PGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPS 214

Query: 88  NPYLGPGYPG-----FGGYSTFRMP----------PHVPPRMSSPYCGPYSLRNQPHPFP 132
                P +PG      GG S  + P          P +PP  S       +L ++P P P
Sbjct: 215 PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR------ALDDKPPP-P 267

Query: 133 QNPLGMGFNRP----HAFNFGPHDNSSFGNPS--YNNALSQNVNMPNQHFRQNPAENFSQ 186
             P+G   NRP     A    P  N+    PS    +A SQ    P    R  P      
Sbjct: 268 PPPVG---NRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP----PP 320

Query: 187 IPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQD 240
           +PP ++     P L    +  ++S    P       +PPP +    + PPP +D
Sbjct: 321 LPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPS---ERPPPPVRD 371



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 47/202 (23%), Positives = 65/202 (32%), Gaps = 25/202 (12%)

Query: 2   PAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPP-- 59
           P  + P P     S  G+     L    + L S           GP  PP SE  PPP  
Sbjct: 311 PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR 370

Query: 60  NPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYC 119
           +P         P   + N  + + LP++     P  P   G  + R  P  P     P  
Sbjct: 371 DPPGRSGPLPPPPPVSRNGSTSRALPAT-----PQLPSRSGVDSPRSGPRPPLPPDRPSA 425

Query: 120 GPYSLRNQPHPFPQNPLGMGFNR-------PHAFNFGPHDNSSFGNP------SYNNALS 166
           G       P P P   +  GF            F F P  +     P      SY + L+
Sbjct: 426 GA-----PPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLA 480

Query: 167 QNVNMPNQHFRQNPAENFSQIP 188
           +N +    + R+  A     IP
Sbjct: 481 RNESRSGSNRRERGAPPLPPIP 502


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 56/234 (23%), Positives = 88/234 (37%), Gaps = 38/234 (16%)

Query: 28  PGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSS 87
           PG + G P+ ++ +     P      +  PPP P++   + ++P +     +   P   S
Sbjct: 155 PGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPS 214

Query: 88  NPYLGPGYPG-----FGGYSTFRMP----------PHVPPRMSSPYCGPYSLRNQPHPFP 132
                P +PG      GG S  + P          P +PP  S       +L ++P P P
Sbjct: 215 PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR------ALDDKPPP-P 267

Query: 133 QNPLGMGFNRP----HAFNFGPHDNSSFGNPS--YNNALSQNVNMPNQHFRQNPAENFSQ 186
             P+G   NRP     A    P  N+    PS    +A SQ    P    R  P      
Sbjct: 268 PPPVG---NRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP----PP 320

Query: 187 IPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQD 240
           +PP ++     P L    +  ++S    P       +PPP +    + PPP +D
Sbjct: 321 LPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPS---ERPPPPVRD 371



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 47/202 (23%), Positives = 65/202 (32%), Gaps = 25/202 (12%)

Query: 2   PAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPP-- 59
           P  + P P     S  G+     L    + L S           GP  PP SE  PPP  
Sbjct: 311 PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR 370

Query: 60  NPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYC 119
           +P         P   + N  + + LP++     P  P   G  + R  P  P     P  
Sbjct: 371 DPPGRSGPLPPPPPVSRNGSTSRALPAT-----PQLPSRSGVDSPRSGPRPPLPPDRPSA 425

Query: 120 GPYSLRNQPHPFPQNPLGMGFNR-------PHAFNFGPHDNSSFGNP------SYNNALS 166
           G       P P P   +  GF            F F P  +     P      SY + L+
Sbjct: 426 GA-----PPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLA 480

Query: 167 QNVNMPNQHFRQNPAENFSQIP 188
           +N +    + R+  A     IP
Sbjct: 481 RNESRSGSNRRERGAPPLPPIP 502


>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
          Length = 1499

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 67/267 (25%), Positives = 102/267 (38%), Gaps = 45/267 (16%)

Query: 111  PPRMSSPYC--GPYSLRNQPHPFPQNPLGMGFNRPH-AFNFGPHDNS----SFGNPSYNN 163
            P + S P    G   L + P P   NP G   + P+      P D +      G+P   +
Sbjct: 872  PDQSSMPMSNVGTTRLSHMPLPPASNPPGTVHSAPNRGLGRRPSDLTISINQMGSPGMGH 931

Query: 164  ALSQNVNMPNQHFRQNPAENFSQIPPQNASQV-----SNPD--LASNFVPGNNSNFTSP- 215
              S  ++  +     +P+ N     PQ  SQ+     +NP   L S  V G++ +  SP 
Sbjct: 932  LKSPTLSQVHSPLVTSPSANLKS--PQTPSQMVPLPSANPPGPLKSPQVLGSSLSVRSPT 989

Query: 216  -----LESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSN 270
                 L+S    +P P      K   P    + G ++N         P LNM+ +   SN
Sbjct: 990  GSPSRLKSPSMAVPSPGWVASPKTAMP----SPGVSQNKQ-------PPLNMNSSTTLSN 1038

Query: 271  IELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSL--- 327
            +E         +     RSSS+ A   NP +G  N       + D   T   N  SL   
Sbjct: 1039 ME------QGTLPPSGPRSSSS-APPANPPSGLMNPSLPFTSSPD--PTPSQNPLSLMMT 1089

Query: 328  HPNRHGHSSSDPVYPCGICTNEVNDDQ 354
              +++   SS P+Y   I T   +DD+
Sbjct: 1090 QMSKYAMPSSTPLYHNAIKTIATSDDE 1116



 Score = 32.3 bits (72), Expect = 0.82
 Identities = 52/225 (23%), Positives = 76/225 (33%), Gaps = 33/225 (14%)

Query: 44   TQGPSFPPLSEYAPPPNPNS-------------DHLVAANPFDDNYNTISYKPLPSSNPY 90
            T  PS P  S  APP NP S             D   + NP       +S   +PSS P 
Sbjct: 1043 TLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSSTPL 1102

Query: 91   LGPGYPGFGGYSTFRMP--PHVPPRMSSPYCGPYSLRNQPHPF------PQNPLGMGFNR 142
                           +P  P +PP       GP    +QP          Q+P+GM    
Sbjct: 1103 YHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNSQPSQMHLNSAAAQSPMGMNLPG 1162

Query: 143  PHAFNFGPHDNSSFGNPSYNNALSQNVNM-PNQHFRQNPAENFSQIPPQNASQVSNPDLA 201
                +  P   +   +P+    L  N+ + PN      P +N   + P     ++ P   
Sbjct: 1163 QQPLSHEP-PPAMLPSPT---PLGSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAP--- 1215

Query: 202  SNFVPGNNSNFTSP--LESNHSFIPPPNTFGQAKAPPPKQDFTQG 244
               VP ++     P  L+  H  + P  T G    P  +Q +  G
Sbjct: 1216 CGPVPSSSQMMPFPPRLQQPHGAMAP--TGGGGGGPGLQQHYPSG 1258


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 44/167 (26%), Positives = 64/167 (38%), Gaps = 24/167 (14%)

Query: 50   PPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNP--YLGPGYPGF-------GG 100
            PP   Y+ PP P+S   +  +P    +N  S  PLP+S+P  + GP  P           
Sbjct: 928  PPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSL 987

Query: 101  YSTFRMPP--HVPPRMSSPYCGP----YSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNS 154
            Y +  +PP  H PP     +  P    +   + PHP      G   + P     GP   S
Sbjct: 988  YHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQP-S 1046

Query: 155  SFGNPSYNNALSQNVNMPNQH--------FRQNPAENFSQIPPQNAS 193
              G      + +     P+ H          Q PA  + Q+PP+ AS
Sbjct: 1047 LRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAAS 1093


>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/135 (27%), Positives = 55/135 (40%), Gaps = 15/135 (11%)

Query: 273 LKNVNR-----NNAVNQENSRSSSTEATNNNPANGTQNKPRQ-PRGAADACTTEKSNKSS 326
           LK  NR     ++A+    S S S   T N  ++   ++P + P  +AD   TE S  S 
Sbjct: 597 LKKRNRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSK 656

Query: 327 LHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAE- 385
              +  G ++    Y C +C    +     +LCE  C   FH  C G++    G  T   
Sbjct: 657 --KSERGVTAKKE-YVCQLCEKPGS----LLLCEGPCCGAFHLACLGLSRRPEGRFTCSE 709

Query: 386 -ASAVWGCDTCMADK 399
            AS +  C  C   K
Sbjct: 710 CASGIHSCFVCKESK 724


>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/135 (27%), Positives = 55/135 (40%), Gaps = 15/135 (11%)

Query: 273 LKNVNR-----NNAVNQENSRSSSTEATNNNPANGTQNKPRQ-PRGAADACTTEKSNKSS 326
           LK  NR     ++A+    S S S   T N  ++   ++P + P  +AD   TE S  S 
Sbjct: 597 LKKRNRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSK 656

Query: 327 LHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAE- 385
              +  G ++    Y C +C    +     +LCE  C   FH  C G++    G  T   
Sbjct: 657 --KSERGVTAKKE-YVCQLCEKPGS----LLLCEGPCCGAFHLACLGLSRRPEGRFTCSE 709

Query: 386 -ASAVWGCDTCMADK 399
            AS +  C  C   K
Sbjct: 710 CASGIHSCFVCKESK 724


>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/135 (27%), Positives = 55/135 (40%), Gaps = 15/135 (11%)

Query: 273 LKNVNR-----NNAVNQENSRSSSTEATNNNPANGTQNKPRQ-PRGAADACTTEKSNKSS 326
           LK  NR     ++A+    S S S   T N  ++   ++P + P  +AD   TE S  S 
Sbjct: 597 LKKRNRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSK 656

Query: 327 LHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAE- 385
              +  G ++    Y C +C    +     +LCE  C   FH  C G++    G  T   
Sbjct: 657 --KSERGVTAKKE-YVCQLCEKPGS----LLLCEGPCCGAFHLACLGLSRRPEGRFTCSE 709

Query: 386 -ASAVWGCDTCMADK 399
            AS +  C  C   K
Sbjct: 710 CASGIHSCFVCKESK 724


>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/135 (27%), Positives = 55/135 (40%), Gaps = 15/135 (11%)

Query: 273 LKNVNR-----NNAVNQENSRSSSTEATNNNPANGTQNKPRQ-PRGAADACTTEKSNKSS 326
           LK  NR     ++A+    S S S   T N  ++   ++P + P  +AD   TE S  S 
Sbjct: 597 LKKRNRASTAASSALGFSKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSK 656

Query: 327 LHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAE- 385
              +  G ++    Y C +C    +     +LCE  C   FH  C G++    G  T   
Sbjct: 657 --KSERGVTAKKE-YVCQLCEKPGS----LLLCEGPCCGAFHLACLGLSRRPEGRFTCSE 709

Query: 386 -ASAVWGCDTCMADK 399
            AS +  C  C   K
Sbjct: 710 CASGIHSCFVCKESK 724


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 35/188 (18%), Positives = 82/188 (43%), Gaps = 12/188 (6%)

Query: 152  DNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSN 211
            D+S   N S ++  S + +  N     N +++       N+S  SN   +SN    ++SN
Sbjct: 913  DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972

Query: 212  FTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNI 271
             +   +S++S                  D +  +  + + NSS      +  D+ N S+ 
Sbjct: 973  SSDSSDSSNS-----------SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021

Query: 272  ELKNVNRNNAVNQENSRSS-STEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPN 330
               + + N++ + ++S SS S+++++++ ++ + N       +  + +++ S+ S    +
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081

Query: 331  RHGHSSSD 338
                 SSD
Sbjct: 1082 SESSDSSD 1089



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 34/175 (19%), Positives = 77/175 (44%), Gaps = 5/175 (2%)

Query: 153 NSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNF 212
           +SS  + S N++ S + +  +     + + + S     N S  SN   +S+    +NS+ 
Sbjct: 819 DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878

Query: 213 TSPL-ESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNI 271
           +S   +SN S     ++     +     D +  +  + + NSS      N  D  N S+ 
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD- 937

Query: 272 ELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSS 326
              + N +++ +  +S +SS  + +++ +N + +       ++D+  +  S+ SS
Sbjct: 938 ---SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 30/190 (15%), Positives = 86/190 (45%), Gaps = 9/190 (4%)

Query: 152 DNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSN 211
           D+S   + S ++  + + N  +     N +++ +     ++S  S+ D +++    N+S+
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831

Query: 212 FTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNI 271
            +    S+ S     ++ G       + D +  +  + + +SS      N  D+ + S+ 
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS------NSSDSSDSSDS 885

Query: 272 ELKNVNRNNAVNQENSRSSSTEATNNNPANGTQN---KPRQPRGAADACTTEKSNKSSLH 328
              + + +++ +  +S S S++++N++ ++ + N          + ++ +++ SN S   
Sbjct: 886 NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 945

Query: 329 PNRHGHSSSD 338
            +    +SSD
Sbjct: 946 DSSDSSNSSD 955



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 26/194 (13%), Positives = 89/194 (45%), Gaps = 2/194 (1%)

Query: 147 NFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVP 206
           N     +SS  + S +++ S +    +     + +++ S+    +++   + D + +   
Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659

Query: 207 GNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTV 266
            N+SN +   +S+ S     ++     +       +  ++++++ + S+     +  D+ 
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719

Query: 267 NQSNIELKNVNRNNAVNQENSRSSS--TEATNNNPANGTQNKPRQPRGAADACTTEKSNK 324
           N ++ +  + N +++ +  NS  SS  ++++N++ ++ + +       +  + +++ S+ 
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779

Query: 325 SSLHPNRHGHSSSD 338
           S+   +    +SSD
Sbjct: 780 SNSSDSNDSSNSSD 793



 Score = 32.7 bits (73), Expect = 0.63
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 10/98 (10%)

Query: 236 PPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEAT 295
           P   D + G   N + NS +     +  D    S+    N N +++   E+  S ST  T
Sbjct: 465 PNSSDESNG---NDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDT 521

Query: 296 NNNPANGTQN-------KPRQPRGAADACTTEKSNKSS 326
           NN+ +NG  N       K    +G +D+  ++ S+ S+
Sbjct: 522 NNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSN 559



 Score = 32.3 bits (72), Expect = 0.82
 Identities = 29/187 (15%), Positives = 81/187 (43%), Gaps = 1/187 (0%)

Query: 153 NSSFGNPSYNNA-LSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSN 211
           NSS  + S N++  S + +  N     + +++ +     ++S  S+   +SN    N+S+
Sbjct: 730 NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789

Query: 212 FTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNI 271
            +S    + +     N+   + +       +  ++ ++N + S+   + +     + S+ 
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849

Query: 272 ELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNR 331
              + + N + +  +S SS +  ++N+  +   +   +   ++D+  +  S+ S    + 
Sbjct: 850 GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909

Query: 332 HGHSSSD 338
           +   SSD
Sbjct: 910 NSSDSSD 916



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 30/187 (16%), Positives = 82/187 (43%), Gaps = 8/187 (4%)

Query: 152 DNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSN 211
           D++S  N S +N    N N  N   + +  +  S     ++S  SN   +S+    ++S+
Sbjct: 516 DSTSDTNNSDSNGNGNNGNDDND--KSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSD 573

Query: 212 FTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNI 271
             S  +S+ S     ++     +       +  ++ +++ + S+       D + ++S+ 
Sbjct: 574 SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD- 632

Query: 272 ELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNR 331
                + ++    ++S S+S+++++N+ ++ + N       +  + +++ S+ S    + 
Sbjct: 633 -----SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687

Query: 332 HGHSSSD 338
               SSD
Sbjct: 688 DSSDSSD 694



 Score = 30.4 bits (67), Expect = 3.1
 Identities = 29/153 (18%), Positives = 66/153 (43%), Gaps = 8/153 (5%)

Query: 191 NASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTN 250
           N+S  SN +  +N    NNS+       N            +K     +D    +T +TN
Sbjct: 466 NSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGA---EDDDSDSTSDTN 522

Query: 251 QNSSAHPPHLNMDDTVNQSNIELK-----NVNRNNAVNQENSRSSSTEATNNNPANGTQN 305
            + S    +   DD     + + K     + + +++ + ++S SS ++++++N ++ + +
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDS 582

Query: 306 KPRQPRGAADACTTEKSNKSSLHPNRHGHSSSD 338
                  ++D+ +++ SN S    +     SSD
Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSD 615



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 29/186 (15%), Positives = 81/186 (43%), Gaps = 3/186 (1%)

Query: 153 NSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNF 212
           +S   N S ++  S + +  +     N +++       N+S  S+   +S+    +NS+ 
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784

Query: 213 TSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIE 272
           ++   ++       N+   + +           + ++N + S++    +  D+ N S+  
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS--DSSDSSNSSDSS 842

Query: 273 LKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRH 332
             + + + + +  ++RS S+ +++++ ++ + N       ++D+  +  S+ SS   N  
Sbjct: 843 DSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS-SDSSDSSDSNESSNSSDSSDSSNSS 901

Query: 333 GHSSSD 338
              SSD
Sbjct: 902 DSDSSD 907



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 32/193 (16%), Positives = 86/193 (44%), Gaps = 9/193 (4%)

Query: 147  NFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVP 206
            N     +SS  N S N++ S + +  +     + + +       N+S  S    +SN   
Sbjct: 875  NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE---SSNSSD 931

Query: 207  GNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTV 266
             +NS+     +S++S     ++     +       +  ++ +++ NSS      N  D+ 
Sbjct: 932  NSNSS-----DSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS 986

Query: 267  NQSNIELKNVNRNNAVNQENSRSS-STEATNNNPANGTQNKPRQPRGAADACTTEKSNKS 325
            + S+    + + +++ + ++S SS S++++N++ ++ + +       +  + +++ S+ S
Sbjct: 987  DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS 1046

Query: 326  SLHPNRHGHSSSD 338
                +    +SSD
Sbjct: 1047 DSSDSSDSSNSSD 1059



 Score = 28.9 bits (63), Expect = 9.1
 Identities = 28/185 (15%), Positives = 76/185 (41%), Gaps = 2/185 (1%)

Query: 153 NSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNF 212
           N+S  N + NN    N    +   + + +++ S     ++    + D  S+    N+S+ 
Sbjct: 522 NNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSD--SDSSDSNSSSD 579

Query: 213 TSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIE 272
           +   +S+ S     ++   + +           + +++ +S +       +   + S+ +
Sbjct: 580 SDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSK 639

Query: 273 LKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRH 332
             + + N++ + +NS SS +  ++N+  +   +       ++D+  +  S+ SS   N  
Sbjct: 640 SDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSS 699

Query: 333 GHSSS 337
             S S
Sbjct: 700 ESSDS 704


>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
          Length = 1083

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 20/76 (26%)

Query: 51  PLSEYAPPPNPNSDHLVAANP--FDDNYNTISYKPLPSSNPY-------------LGPGY 95
           P   Y P P+P S H VA +P  + + ++  SY P PS   Y             + PG 
Sbjct: 894 PQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGA 953

Query: 96  PGFGGYSTFRMPPHVP 111
           P  GGY+     PH P
Sbjct: 954 PSPGGYN-----PHTP 964


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 20/76 (26%)

Query: 51  PLSEYAPPPNPNSDHLVAANP--FDDNYNTISYKPLPSSNPY-------------LGPGY 95
           P   Y P P+P S H VA +P  + + ++  SY P PS   Y             + PG 
Sbjct: 898 PQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGA 957

Query: 96  PGFGGYSTFRMPPHVP 111
           P  GGY+     PH P
Sbjct: 958 PSPGGYN-----PHTP 968


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 20/76 (26%)

Query: 51  PLSEYAPPPNPNSDHLVAANP--FDDNYNTISYKPLPSSNPY-------------LGPGY 95
           P   Y P P+P S H VA +P  + + ++  SY P PS   Y             + PG 
Sbjct: 898 PQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGA 957

Query: 96  PGFGGYSTFRMPPHVP 111
           P  GGY+     PH P
Sbjct: 958 PSPGGYN-----PHTP 968


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 20/76 (26%)

Query: 51  PLSEYAPPPNPNSDHLVAANP--FDDNYNTISYKPLPSSNPY-------------LGPGY 95
           P   Y P P+P S H VA +P  + + ++  SY P PS   Y             + PG 
Sbjct: 898 PQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGA 957

Query: 96  PGFGGYSTFRMPPHVP 111
           P  GGY+     PH P
Sbjct: 958 PSPGGYN-----PHTP 968


>gi|57165375 glutamate receptor, ionotropic, N-methyl
           D-aspartate-associated protein 1 [Homo sapiens]
          Length = 371

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 41/125 (32%), Positives = 51/125 (40%), Gaps = 16/125 (12%)

Query: 46  GPSFPPLSEYAPPPNPNSDHLVAANPFDDN-YNTISYKPLPSSNPYLGPGYPGFGGYSTF 104
           GP  PP+  YA PP P + +     PF  + Y    Y   PS  PY   GYP  G Y   
Sbjct: 24  GPQ-PPMPPYAQPPYPGAPY--PQPPFQPSPYGQPGYPHGPS--PYPQGGYPQ-GPYPQG 77

Query: 105 RMPPHVPPRMSSPYCGPYSLRNQPH-PFPQNPLGMG-FNRPHAFNFGPHDNSSFGN---- 158
             P    P+   P  GPY     P  P+PQ+P     + +P  F     D+   GN    
Sbjct: 78  GYPQGPYPQEGYPQ-GPYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDPDSPQHGNYQEE 136

Query: 159 --PSY 161
             PSY
Sbjct: 137 GPPSY 141



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 47/193 (24%), Positives = 59/193 (30%), Gaps = 45/193 (23%)

Query: 48  SFPPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMP 107
           SF    +  PPPNP                     P P   PY  P YPG         P
Sbjct: 6   SFLVSGDNYPPPNPGYPG----------------GPQPPMPPYAQPPYPG--------AP 41

Query: 108 PHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQ 167
              PP   SPY  P    + P P+PQ     G      +  GP+    +    Y      
Sbjct: 42  YPQPPFQPSPYGQP-GYPHGPSPYPQGGYPQGPYPQGGYPQGPYPQEGYPQGPY------ 94

Query: 168 NVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPN 227
               P   + Q P    S  PP       NP       PG + +  SP   N+    PP+
Sbjct: 95  ----PQGGYPQGPYPQ-SPFPP-------NPYGQPQVFPGQDPD--SPQHGNYQEEGPPS 140

Query: 228 TFGQAKAPPPKQD 240
            +     P    D
Sbjct: 141 YYDNQDFPATNWD 153


>gi|57165373 glutamate receptor, ionotropic, N-methyl
           D-aspartate-associated protein 1 [Homo sapiens]
          Length = 371

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 41/125 (32%), Positives = 51/125 (40%), Gaps = 16/125 (12%)

Query: 46  GPSFPPLSEYAPPPNPNSDHLVAANPFDDN-YNTISYKPLPSSNPYLGPGYPGFGGYSTF 104
           GP  PP+  YA PP P + +     PF  + Y    Y   PS  PY   GYP  G Y   
Sbjct: 24  GPQ-PPMPPYAQPPYPGAPY--PQPPFQPSPYGQPGYPHGPS--PYPQGGYPQ-GPYPQG 77

Query: 105 RMPPHVPPRMSSPYCGPYSLRNQPH-PFPQNPLGMG-FNRPHAFNFGPHDNSSFGN---- 158
             P    P+   P  GPY     P  P+PQ+P     + +P  F     D+   GN    
Sbjct: 78  GYPQGPYPQEGYPQ-GPYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDPDSPQHGNYQEE 136

Query: 159 --PSY 161
             PSY
Sbjct: 137 GPPSY 141



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 47/193 (24%), Positives = 59/193 (30%), Gaps = 45/193 (23%)

Query: 48  SFPPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMP 107
           SF    +  PPPNP                     P P   PY  P YPG         P
Sbjct: 6   SFLVSGDNYPPPNPGYPG----------------GPQPPMPPYAQPPYPG--------AP 41

Query: 108 PHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQ 167
              PP   SPY  P    + P P+PQ     G      +  GP+    +    Y      
Sbjct: 42  YPQPPFQPSPYGQP-GYPHGPSPYPQGGYPQGPYPQGGYPQGPYPQEGYPQGPY------ 94

Query: 168 NVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPN 227
               P   + Q P    S  PP       NP       PG + +  SP   N+    PP+
Sbjct: 95  ----PQGGYPQGPYPQ-SPFPP-------NPYGQPQVFPGQDPD--SPQHGNYQEEGPPS 140

Query: 228 TFGQAKAPPPKQD 240
            +     P    D
Sbjct: 141 YYDNQDFPATNWD 153


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.129    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,721,283
Number of Sequences: 37866
Number of extensions: 1286534
Number of successful extensions: 5032
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 311
Number of HSP's that attempted gapping in prelim test: 4414
Number of HSP's gapped (non-prelim): 829
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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