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Search of human proteins with 30089952
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30089952 protein tyrosine phosphatase domain containing 1
protein isoform 1 [Homo sapiens]
(806 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30089952 protein tyrosine phosphatase domain containing 1 pro... 1628 0.0
gi|30089950 protein tyrosine phosphatase domain containing 1 pro... 1479 0.0
gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens] 69 2e-11
gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens] 69 2e-11
gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens] 69 2e-11
gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens] 57 7e-08
gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens] 57 7e-08
gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens] 57 7e-08
gi|56786144 dual specificity phosphatase 23 [Homo sapiens] 52 2e-06
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 44 6e-04
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 44 6e-04
gi|18104993 protein tyrosine phosphatase, non-receptor type 6 is... 43 0.001
gi|18104989 protein tyrosine phosphatase, non-receptor type 6 is... 43 0.001
gi|18104991 protein tyrosine phosphatase, non-receptor type 6 is... 43 0.001
gi|148539860 protein tyrosine phosphatase, receptor type, T isof... 43 0.001
gi|148539858 protein tyrosine phosphatase, receptor type, T isof... 43 0.001
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 43 0.001
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 43 0.001
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 43 0.001
gi|195927025 cyclin-dependent kinase inhibitor 3 isoform 2 [Homo... 42 0.002
gi|17981704 cyclin-dependent kinase inhibitor 3 isoform 1 [Homo ... 42 0.002
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 42 0.003
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 42 0.003
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 42 0.003
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 42 0.003
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 42 0.003
gi|4506283 protein tyrosine phosphatase type IVA, member 1 [Homo... 41 0.004
gi|14589856 protein tyrosine phosphatase type IVA, member 3 isof... 41 0.004
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 41 0.005
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 41 0.005
>gi|30089952 protein tyrosine phosphatase domain containing 1
protein isoform 1 [Homo sapiens]
Length = 806
Score = 1628 bits (4217), Expect = 0.0
Identities = 806/806 (100%), Positives = 806/806 (100%)
Query: 1 MQVQDATRRPSAVRFLSSFLQGRRHSTSDPVLRLQQARRGSGLGSGSATKLLSSSSLQVM 60
MQVQDATRRPSAVRFLSSFLQGRRHSTSDPVLRLQQARRGSGLGSGSATKLLSSSSLQVM
Sbjct: 1 MQVQDATRRPSAVRFLSSFLQGRRHSTSDPVLRLQQARRGSGLGSGSATKLLSSSSLQVM 60
Query: 61 VAVSSVSHAEGNPTFPERKRNLERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENP 120
VAVSSVSHAEGNPTFPERKRNLERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENP
Sbjct: 61 VAVSSVSHAEGNPTFPERKRNLERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENP 120
Query: 121 ARWSEQEQAIKGVYSSWVTDNILAMARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHA 180
ARWSEQEQAIKGVYSSWVTDNILAMARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHA
Sbjct: 121 ARWSEQEQAIKGVYSSWVTDNILAMARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHA 180
Query: 181 SCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAI 240
SCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAI
Sbjct: 181 SCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAI 240
Query: 241 HCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLTPLR 300
HCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLTPLR
Sbjct: 241 HCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLTPLR 300
Query: 301 NIFSCCDPKAHAVTLPQYLIRQRHLLHGYEARLLKHVPKIIHLVCKLLLDLAENRPVMMK 360
NIFSCCDPKAHAVTLPQYLIRQRHLLHGYEARLLKHVPKIIHLVCKLLLDLAENRPVMMK
Sbjct: 301 NIFSCCDPKAHAVTLPQYLIRQRHLLHGYEARLLKHVPKIIHLVCKLLLDLAENRPVMMK 360
Query: 361 DVSEGPGLSAEIEKTMSEMVTMQLDKELLRHDSDVSNPPNPTAVAADFDNRGMIFSNEQQ 420
DVSEGPGLSAEIEKTMSEMVTMQLDKELLRHDSDVSNPPNPTAVAADFDNRGMIFSNEQQ
Sbjct: 361 DVSEGPGLSAEIEKTMSEMVTMQLDKELLRHDSDVSNPPNPTAVAADFDNRGMIFSNEQQ 420
Query: 421 FDPLWKRRNVECLQPLTHLKRRLSYSDSDLKRAENLLEQGETPQTVPAQILVGHKPRQQK 480
FDPLWKRRNVECLQPLTHLKRRLSYSDSDLKRAENLLEQGETPQTVPAQILVGHKPRQQK
Sbjct: 421 FDPLWKRRNVECLQPLTHLKRRLSYSDSDLKRAENLLEQGETPQTVPAQILVGHKPRQQK 480
Query: 481 LISHCYIPQSPEPDLHKEALVRSTLSFWSQSKFGGLEGLKDNGSPIFHGRIIPKEAQQSG 540
LISHCYIPQSPEPDLHKEALVRSTLSFWSQSKFGGLEGLKDNGSPIFHGRIIPKEAQQSG
Sbjct: 481 LISHCYIPQSPEPDLHKEALVRSTLSFWSQSKFGGLEGLKDNGSPIFHGRIIPKEAQQSG 540
Query: 541 AFSADVSGSHSPGEPVSPSFANVHKDPNPAHQQVSHCQCKTHGVGSPGSVRQNSRTPRSP 600
AFSADVSGSHSPGEPVSPSFANVHKDPNPAHQQVSHCQCKTHGVGSPGSVRQNSRTPRSP
Sbjct: 541 AFSADVSGSHSPGEPVSPSFANVHKDPNPAHQQVSHCQCKTHGVGSPGSVRQNSRTPRSP 600
Query: 601 LDCGSSPKAQFLVEHETQDSKDLSEAASHSALQSELSAEARRILAAKALANLNESVEKEE 660
LDCGSSPKAQFLVEHETQDSKDLSEAASHSALQSELSAEARRILAAKALANLNESVEKEE
Sbjct: 601 LDCGSSPKAQFLVEHETQDSKDLSEAASHSALQSELSAEARRILAAKALANLNESVEKEE 660
Query: 661 LKRKVEMWQKELNSRDGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRRA 720
LKRKVEMWQKELNSRDGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRRA
Sbjct: 661 LKRKVEMWQKELNSRDGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRRA 720
Query: 721 DAAEALFLLEKGQHQTILCVLHCIVNLQTIPVDVEEAFLAHAIKAFTKVNFDSENGPTVY 780
DAAEALFLLEKGQHQTILCVLHCIVNLQTIPVDVEEAFLAHAIKAFTKVNFDSENGPTVY
Sbjct: 721 DAAEALFLLEKGQHQTILCVLHCIVNLQTIPVDVEEAFLAHAIKAFTKVNFDSENGPTVY 780
Query: 781 NTLKKIFKHTLEEKRKMTKDGPKPGL 806
NTLKKIFKHTLEEKRKMTKDGPKPGL
Sbjct: 781 NTLKKIFKHTLEEKRKMTKDGPKPGL 806
>gi|30089950 protein tyrosine phosphatase domain containing 1
protein isoform 2 [Homo sapiens]
Length = 754
Score = 1479 bits (3830), Expect = 0.0
Identities = 727/728 (99%), Positives = 727/728 (99%)
Query: 79 KRNLERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENPARWSEQEQAIKGVYSSWV 138
K NLERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENPARWSEQEQAIKGVYSSWV
Sbjct: 27 KGNLERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENPARWSEQEQAIKGVYSSWV 86
Query: 139 TDNILAMARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHASCGNPLEQESGFTYLPEA 198
TDNILAMARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHASCGNPLEQESGFTYLPEA
Sbjct: 87 TDNILAMARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHASCGNPLEQESGFTYLPEA 146
Query: 199 FMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLV 258
FMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLV
Sbjct: 147 FMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLV 206
Query: 259 FATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLTPLRNIFSCCDPKAHAVTLPQY 318
FATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLTPLRNIFSCCDPKAHAVTLPQY
Sbjct: 207 FATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLTPLRNIFSCCDPKAHAVTLPQY 266
Query: 319 LIRQRHLLHGYEARLLKHVPKIIHLVCKLLLDLAENRPVMMKDVSEGPGLSAEIEKTMSE 378
LIRQRHLLHGYEARLLKHVPKIIHLVCKLLLDLAENRPVMMKDVSEGPGLSAEIEKTMSE
Sbjct: 267 LIRQRHLLHGYEARLLKHVPKIIHLVCKLLLDLAENRPVMMKDVSEGPGLSAEIEKTMSE 326
Query: 379 MVTMQLDKELLRHDSDVSNPPNPTAVAADFDNRGMIFSNEQQFDPLWKRRNVECLQPLTH 438
MVTMQLDKELLRHDSDVSNPPNPTAVAADFDNRGMIFSNEQQFDPLWKRRNVECLQPLTH
Sbjct: 327 MVTMQLDKELLRHDSDVSNPPNPTAVAADFDNRGMIFSNEQQFDPLWKRRNVECLQPLTH 386
Query: 439 LKRRLSYSDSDLKRAENLLEQGETPQTVPAQILVGHKPRQQKLISHCYIPQSPEPDLHKE 498
LKRRLSYSDSDLKRAENLLEQGETPQTVPAQILVGHKPRQQKLISHCYIPQSPEPDLHKE
Sbjct: 387 LKRRLSYSDSDLKRAENLLEQGETPQTVPAQILVGHKPRQQKLISHCYIPQSPEPDLHKE 446
Query: 499 ALVRSTLSFWSQSKFGGLEGLKDNGSPIFHGRIIPKEAQQSGAFSADVSGSHSPGEPVSP 558
ALVRSTLSFWSQSKFGGLEGLKDNGSPIFHGRIIPKEAQQSGAFSADVSGSHSPGEPVSP
Sbjct: 447 ALVRSTLSFWSQSKFGGLEGLKDNGSPIFHGRIIPKEAQQSGAFSADVSGSHSPGEPVSP 506
Query: 559 SFANVHKDPNPAHQQVSHCQCKTHGVGSPGSVRQNSRTPRSPLDCGSSPKAQFLVEHETQ 618
SFANVHKDPNPAHQQVSHCQCKTHGVGSPGSVRQNSRTPRSPLDCGSSPKAQFLVEHETQ
Sbjct: 507 SFANVHKDPNPAHQQVSHCQCKTHGVGSPGSVRQNSRTPRSPLDCGSSPKAQFLVEHETQ 566
Query: 619 DSKDLSEAASHSALQSELSAEARRILAAKALANLNESVEKEELKRKVEMWQKELNSRDGA 678
DSKDLSEAASHSALQSELSAEARRILAAKALANLNESVEKEELKRKVEMWQKELNSRDGA
Sbjct: 567 DSKDLSEAASHSALQSELSAEARRILAAKALANLNESVEKEELKRKVEMWQKELNSRDGA 626
Query: 679 WERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRRADAAEALFLLEKGQHQTIL 738
WERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRRADAAEALFLLEKGQHQTIL
Sbjct: 627 WERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRRADAAEALFLLEKGQHQTIL 686
Query: 739 CVLHCIVNLQTIPVDVEEAFLAHAIKAFTKVNFDSENGPTVYNTLKKIFKHTLEEKRKMT 798
CVLHCIVNLQTIPVDVEEAFLAHAIKAFTKVNFDSENGPTVYNTLKKIFKHTLEEKRKMT
Sbjct: 687 CVLHCIVNLQTIPVDVEEAFLAHAIKAFTKVNFDSENGPTVYNTLKKIFKHTLEEKRKMT 746
Query: 799 KDGPKPGL 806
KDGPKPGL
Sbjct: 747 KDGPKPGL 754
>gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens]
Length = 461
Score = 68.6 bits (166), Expect = 2e-11
Identities = 51/170 (30%), Positives = 76/170 (44%), Gaps = 26/170 (15%)
Query: 119 NPARWSEQEQAIKGVYSSWVTDNILAMARPSSE--LLEKYH------IIDQFLSHGIKTI 170
N + E+A G + + D +A P S L YH I F +H + TI
Sbjct: 164 NLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTI 223
Query: 171 INLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMT 230
I L + Y + F +AG ++ + D + + + + +
Sbjct: 224 IRLNKR----------------MYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICE 267
Query: 231 FALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSI 280
A EG +A+HC AGLGRTG LIACY++ RMTA + I +VR RP S+
Sbjct: 268 NA--EGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSV 315
>gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens]
Length = 459
Score = 68.6 bits (166), Expect = 2e-11
Identities = 51/170 (30%), Positives = 76/170 (44%), Gaps = 26/170 (15%)
Query: 119 NPARWSEQEQAIKGVYSSWVTDNILAMARPSSE--LLEKYH------IIDQFLSHGIKTI 170
N + E+A G + + D +A P S L YH I F +H + TI
Sbjct: 201 NLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTI 260
Query: 171 INLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMT 230
I L + Y + F +AG ++ + D + + + + +
Sbjct: 261 IRLNKR----------------MYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICE 304
Query: 231 FALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSI 280
A EG +A+HC AGLGRTG LIACY++ RMTA + I +VR RP S+
Sbjct: 305 NA--EGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSV 352
>gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens]
Length = 498
Score = 68.6 bits (166), Expect = 2e-11
Identities = 51/170 (30%), Positives = 76/170 (44%), Gaps = 26/170 (15%)
Query: 119 NPARWSEQEQAIKGVYSSWVTDNILAMARPSSE--LLEKYH------IIDQFLSHGIKTI 170
N + E+A G + + D +A P S L YH I F +H + TI
Sbjct: 201 NLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTI 260
Query: 171 INLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMT 230
I L + Y + F +AG ++ + D + + + + +
Sbjct: 261 IRLNKR----------------MYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDICE 304
Query: 231 FALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSI 280
A EG +A+HC AGLGRTG LIACY++ RMTA + I +VR RP S+
Sbjct: 305 NA--EGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSV 352
>gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]
Length = 383
Score = 57.0 bits (136), Expect = 7e-08
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
Query: 194 YLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLI 253
Y + F +AG Y+ + D S + + + EG +A+HC AGLGRTG LI
Sbjct: 232 YEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENT--EGAIAVHCKAGLGRTGTLI 289
Query: 254 ACYLVFATRMTADQAIIFVRAKRPNSI 280
ACY++ R T + I ++R RP SI
Sbjct: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
>gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens]
Length = 594
Score = 57.0 bits (136), Expect = 7e-08
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
Query: 194 YLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLI 253
Y + F +AG Y+ + D S + + + EG +A+HC AGLGRTG LI
Sbjct: 232 YEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENT--EGAIAVHCKAGLGRTGTLI 289
Query: 254 ACYLVFATRMTADQAIIFVRAKRPNSI 280
ACY++ R T + I ++R RP SI
Sbjct: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
>gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]
Length = 623
Score = 57.0 bits (136), Expect = 7e-08
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
Query: 194 YLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLI 253
Y + F +AG Y+ + D S + + + EG +A+HC AGLGRTG LI
Sbjct: 232 YEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENT--EGAIAVHCKAGLGRTGTLI 289
Query: 254 ACYLVFATRMTADQAIIFVRAKRPNSI 280
ACY++ R T + I ++R RP SI
Sbjct: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
>gi|56786144 dual specificity phosphatase 23 [Homo sapiens]
Length = 150
Score = 52.0 bits (123), Expect = 2e-06
Identities = 26/57 (45%), Positives = 33/57 (57%)
Query: 238 VAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQ 294
V +HC G GRTG ++ACYLV + A AI +R RP SI+T Q V +F Q
Sbjct: 91 VGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQ 147
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 43.9 bits (102), Expect = 6e-04
Identities = 26/70 (37%), Positives = 38/70 (54%), Gaps = 8/70 (11%)
Query: 234 QEGKVAIHCHAGLGRTGVLIACYLVFATRMTAD------QAIIFVRAKRPNSIQTRGQL- 286
Q+G + +HC AG+GRTGV I +V RM + Q + +R +RP +QT Q
Sbjct: 1831 QDGPITVHCSAGVGRTGVFITLSIVL-ERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQ 1889
Query: 287 LCVREFTQFL 296
LC R ++L
Sbjct: 1890 LCYRAALEYL 1899
Score = 38.1 bits (87), Expect = 0.033
Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 17/95 (17%)
Query: 206 FYNFGWKDYGVASLTT----ILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFAT 261
F W D+GV T L VK L G + +HC AG+GRTG C++V
Sbjct: 1509 FQFMAWPDHGVPEYPTPILAFLRRVKACN-PLDAGPMVVHCSAGVGRTG----CFIVIDA 1563
Query: 262 RMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFL 296
+ R K ++ G + C+R ++
Sbjct: 1564 MLE--------RMKHEKTVDIYGHVTCMRSQRNYM 1590
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 43.9 bits (102), Expect = 6e-04
Identities = 26/70 (37%), Positives = 38/70 (54%), Gaps = 8/70 (11%)
Query: 234 QEGKVAIHCHAGLGRTGVLIACYLVFATRMTAD------QAIIFVRAKRPNSIQTRGQL- 286
Q+G + +HC AG+GRTGV I +V RM + Q + +R +RP +QT Q
Sbjct: 1822 QDGPITVHCSAGVGRTGVFITLSIVL-ERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQ 1880
Query: 287 LCVREFTQFL 296
LC R ++L
Sbjct: 1881 LCYRAALEYL 1890
Score = 38.1 bits (87), Expect = 0.033
Identities = 26/95 (27%), Positives = 39/95 (41%), Gaps = 17/95 (17%)
Query: 206 FYNFGWKDYGVASLTT----ILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFAT 261
F W D+GV T L VK L G + +HC AG+GRTG C++V
Sbjct: 1500 FQFMAWPDHGVPEYPTPILAFLRRVKACN-PLDAGPMVVHCSAGVGRTG----CFIVIDA 1554
Query: 262 RMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFL 296
+ R K ++ G + C+R ++
Sbjct: 1555 MLE--------RMKHEKTVDIYGHVTCMRSQRNYM 1581
>gi|18104993 protein tyrosine phosphatase, non-receptor type 6
isoform 3 [Homo sapiens]
Length = 624
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 14/96 (14%)
Query: 204 IYFYNF-GWKDYGVAS----LTTILDMVKVMTFALQE-GKVAIHCHAGLGRTGVLIACYL 257
I+ Y + W D+GV S + + LD + +L G + +HC AG+GRTG +I +
Sbjct: 409 IWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDM 468
Query: 258 VFATRMT--------ADQAIIFVRAKRPNSIQTRGQ 285
+ T + I VRA+R +QT Q
Sbjct: 469 LMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQ 504
>gi|18104989 protein tyrosine phosphatase, non-receptor type 6
isoform 1 [Homo sapiens]
Length = 595
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 14/96 (14%)
Query: 204 IYFYNF-GWKDYGVAS----LTTILDMVKVMTFALQE-GKVAIHCHAGLGRTGVLIACYL 257
I+ Y + W D+GV S + + LD + +L G + +HC AG+GRTG +I +
Sbjct: 409 IWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDM 468
Query: 258 VFATRMT--------ADQAIIFVRAKRPNSIQTRGQ 285
+ T + I VRA+R +QT Q
Sbjct: 469 LMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQ 504
>gi|18104991 protein tyrosine phosphatase, non-receptor type 6
isoform 2 [Homo sapiens]
Length = 597
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 14/96 (14%)
Query: 204 IYFYNF-GWKDYGVAS----LTTILDMVKVMTFALQE-GKVAIHCHAGLGRTGVLIACYL 257
I+ Y + W D+GV S + + LD + +L G + +HC AG+GRTG +I +
Sbjct: 411 IWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDM 470
Query: 258 VFATRMT--------ADQAIIFVRAKRPNSIQTRGQ 285
+ T + I VRA+R +QT Q
Sbjct: 471 LMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQ 506
>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
precursor [Homo sapiens]
Length = 1441
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 206 FYNFGWKDYGVASLTT-ILDMVKVMTFAL--QEGKVAIHCHAGLGRTGVLIACYLVFATR 262
F+ W D+GV T +L V+ + F + G + +HC AG GRTG IA +
Sbjct: 1045 FHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMA 1104
Query: 263 MTADQAIIF-----VRAKRPNSIQTRGQLLCVRE 291
IF +RA+R N +QT Q + V +
Sbjct: 1105 ENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHD 1138
>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
precursor [Homo sapiens]
Length = 1460
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 206 FYNFGWKDYGVASLTT-ILDMVKVMTFAL--QEGKVAIHCHAGLGRTGVLIACYLVFATR 262
F+ W D+GV T +L V+ + F + G + +HC AG GRTG IA +
Sbjct: 1064 FHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMA 1123
Query: 263 MTADQAIIF-----VRAKRPNSIQTRGQLLCVRE 291
IF +RA+R N +QT Q + V +
Sbjct: 1124 ENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHD 1157
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/60 (43%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 232 ALQEGK-VAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRP---NSIQTRGQLL 287
A Q GK + IHC AG+ R+ ++ YL+ TRMT A FV+ KRP ++ GQLL
Sbjct: 55 AHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLL 114
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/60 (43%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 232 ALQEGK-VAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRP---NSIQTRGQLL 287
A Q GK + IHC AG+ R+ ++ YL+ TRMT A FV+ KRP ++ GQLL
Sbjct: 55 AHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLL 114
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/60 (43%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 232 ALQEGK-VAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRP---NSIQTRGQLL 287
A Q GK + IHC AG+ R+ ++ YL+ TRMT A FV+ KRP ++ GQLL
Sbjct: 397 AHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLL 456
>gi|195927025 cyclin-dependent kinase inhibitor 3 isoform 2 [Homo
sapiens]
Length = 172
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/101 (28%), Positives = 55/101 (54%), Gaps = 3/101 (2%)
Query: 195 LPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQE-GKVAIHCHAGLGRTGVLI 253
L + + + GI ++ D G + + ++++ +T L+ K IHC+ GLGR+ ++
Sbjct: 52 LLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLVA 111
Query: 254 ACYLVF-ATRMTADQAIIFVRAKR-PNSIQTRGQLLCVREF 292
AC L++ + ++ +QAI +R R +IQT Q + EF
Sbjct: 112 ACLLLYLSDTISPEQAIDSLRDLRGSGAIQTIKQYNYLHEF 152
>gi|17981704 cyclin-dependent kinase inhibitor 3 isoform 1 [Homo
sapiens]
Length = 212
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/101 (28%), Positives = 55/101 (54%), Gaps = 3/101 (2%)
Query: 195 LPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQE-GKVAIHCHAGLGRTGVLI 253
L + + + GI ++ D G + + ++++ +T L+ K IHC+ GLGR+ ++
Sbjct: 92 LLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLVA 151
Query: 254 ACYLVF-ATRMTADQAIIFVRAKR-PNSIQTRGQLLCVREF 292
AC L++ + ++ +QAI +R R +IQT Q + EF
Sbjct: 152 ACLLLYLSDTISPEQAIDSLRDLRGSGAIQTIKQYNYLHEF 192
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
precursor [Homo sapiens]
Length = 1502
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/58 (37%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Query: 234 QEGKVAIHCHAGLGRTGVLIACYLVFATRMTAD------QAIIFVRAKRPNSIQTRGQ 285
Q+G +++HC AG+GRTGV I +V RM + Q + +R +RP +QT Q
Sbjct: 1426 QDGPISVHCSAGVGRTGVFITLSIVL-ERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQ 1482
Score = 33.5 bits (75), Expect = 0.81
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 18/94 (19%)
Query: 211 WKDYGVASLTT----ILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRM--- 263
W D+GV T L VK G + +HC AG+GRTG C++V +
Sbjct: 1109 WPDHGVPEHPTPFLAFLRRVKTCN-PPDAGPMVVHCSAGVGRTG----CFIVIDAMLERI 1163
Query: 264 ----TAD--QAIIFVRAKRPNSIQTRGQLLCVRE 291
T D + +RA+R +QT Q + + +
Sbjct: 1164 KHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHD 1197
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/58 (37%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Query: 234 QEGKVAIHCHAGLGRTGVLIACYLVFATRMTAD------QAIIFVRAKRPNSIQTRGQ 285
Q+G +++HC AG+GRTGV I +V RM + Q + +R +RP +QT Q
Sbjct: 1836 QDGPISVHCSAGVGRTGVFITLSIVL-ERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQ 1892
Score = 33.5 bits (75), Expect = 0.81
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 18/94 (19%)
Query: 211 WKDYGVASLTT----ILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRM--- 263
W D+GV T L VK G + +HC AG+GRTG C++V +
Sbjct: 1519 WPDHGVPEHPTPFLAFLRRVKTCN-PPDAGPMVVHCSAGVGRTG----CFIVIDAMLERI 1573
Query: 264 ----TAD--QAIIFVRAKRPNSIQTRGQLLCVRE 291
T D + +RA+R +QT Q + + +
Sbjct: 1574 KHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHD 1607
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
precursor [Homo sapiens]
Length = 1899
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/58 (37%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Query: 234 QEGKVAIHCHAGLGRTGVLIACYLVFATRMTAD------QAIIFVRAKRPNSIQTRGQ 285
Q+G +++HC AG+GRTGV I +V RM + Q + +R +RP +QT Q
Sbjct: 1823 QDGPISVHCSAGVGRTGVFITLSIVL-ERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQ 1879
Score = 33.5 bits (75), Expect = 0.81
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 18/94 (19%)
Query: 211 WKDYGVASLTT----ILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRM--- 263
W D+GV T L VK G + +HC AG+GRTG C++V +
Sbjct: 1506 WPDHGVPEHPTPFLAFLRRVKTCN-PPDAGPMVVHCSAGVGRTG----CFIVIDAMLERI 1560
Query: 264 ----TAD--QAIIFVRAKRPNSIQTRGQLLCVRE 291
T D + +RA+R +QT Q + + +
Sbjct: 1561 KHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHD 1594
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/58 (37%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Query: 234 QEGKVAIHCHAGLGRTGVLIACYLVFATRMTAD------QAIIFVRAKRPNSIQTRGQ 285
Q+G +++HC AG+GRTGV I +V RM + Q + +R +RP +QT Q
Sbjct: 1827 QDGPISVHCSAGVGRTGVFITLSIVL-ERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQ 1883
Score = 33.5 bits (75), Expect = 0.81
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 18/94 (19%)
Query: 211 WKDYGVASLTT----ILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRM--- 263
W D+GV T L VK G + +HC AG+GRTG C++V +
Sbjct: 1510 WPDHGVPEHPTPFLAFLRRVKTCN-PPDAGPMVVHCSAGVGRTG----CFIVIDAMLERI 1564
Query: 264 ----TAD--QAIIFVRAKRPNSIQTRGQLLCVRE 291
T D + +RA+R +QT Q + + +
Sbjct: 1565 KHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHD 1598
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform 4
precursor [Homo sapiens]
Length = 1501
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/58 (37%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Query: 234 QEGKVAIHCHAGLGRTGVLIACYLVFATRMTAD------QAIIFVRAKRPNSIQTRGQ 285
Q+G +++HC AG+GRTGV I +V RM + Q + +R +RP +QT Q
Sbjct: 1425 QDGPISVHCSAGVGRTGVFITLSIVL-ERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQ 1481
Score = 33.5 bits (75), Expect = 0.81
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 18/94 (19%)
Query: 211 WKDYGVASLTT----ILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRM--- 263
W D+GV T L VK G + +HC AG+GRTG C++V +
Sbjct: 1108 WPDHGVPEHPTPFLAFLRRVKTCN-PPDAGPMVVHCSAGVGRTG----CFIVIDAMLERI 1162
Query: 264 ----TAD--QAIIFVRAKRPNSIQTRGQLLCVRE 291
T D + +RA+R +QT Q + + +
Sbjct: 1163 KHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHD 1196
>gi|4506283 protein tyrosine phosphatase type IVA, member 1 [Homo
sapiens]
Length = 173
Score = 41.2 bits (95), Expect = 0.004
Identities = 36/148 (24%), Positives = 68/148 (45%), Gaps = 23/148 (15%)
Query: 148 PSSELLEKYHIIDQFLSHGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFY 207
P++ L K+ I++ +G+ TI+ + TY + GI+
Sbjct: 25 PTNATLNKF--IEELKKYGVTTIVRVCEA----------------TYDTTLVEKEGIHVL 66
Query: 208 NFGWKDYGVASLTTILDMVKVMTFALQEGK---VAIHCHAGLGRTGVLIACYLVFATRMT 264
++ + D S + D + ++ +E +A+HC AGLGR VL+A L+ M
Sbjct: 67 DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI-EGGMK 125
Query: 265 ADQAIIFVRAKRPNSIQTRGQLLCVREF 292
+ A+ F+R KR + ++ QLL + ++
Sbjct: 126 YEDAVQFIRQKRRGAFNSK-QLLYLEKY 152
>gi|14589856 protein tyrosine phosphatase type IVA, member 3 isoform
1 [Homo sapiens]
Length = 173
Score = 41.2 bits (95), Expect = 0.004
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 7/89 (7%)
Query: 223 LDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQT 282
L +VK VA+HC AGLGR VL+A L+ + M + AI F+R KR +I +
Sbjct: 85 LSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI-ESGMKYEDAIQFIRQKRRGAINS 143
Query: 283 RGQLLCVREF-----TQFLTPLRNIFSCC 306
+ QL + ++ +F P + CC
Sbjct: 144 K-QLTYLEKYRPKQRLRFKDPHTHKTRCC 171
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 40.8 bits (94), Expect = 0.005
Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 8/70 (11%)
Query: 234 QEGKVAIHCHAGLGRTGVLIACYLVFATRMTAD------QAIIFVRAKRPNSIQTRGQL- 286
Q+G +++HC AG+GRTGV I +V RM + Q + +R +RP +QT +
Sbjct: 1429 QDGPISVHCSAGVGRTGVFITLSIVL-ERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQ 1487
Query: 287 LCVREFTQFL 296
C + ++L
Sbjct: 1488 FCYQAALEYL 1497
Score = 33.5 bits (75), Expect = 0.81
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 18/94 (19%)
Query: 211 WKDYGVASLTT----ILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRM--- 263
W D+GV T L VK G + +HC AG+GRTG C++V +
Sbjct: 1112 WPDHGVPEYPTPFLAFLRRVKTCN-PPDAGPIVVHCSAGVGRTG----CFIVIDAMLERI 1166
Query: 264 ----TAD--QAIIFVRAKRPNSIQTRGQLLCVRE 291
T D + +R++R +QT Q + E
Sbjct: 1167 KPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHE 1200
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 40.8 bits (94), Expect = 0.005
Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 8/70 (11%)
Query: 234 QEGKVAIHCHAGLGRTGVLIACYLVFATRMTAD------QAIIFVRAKRPNSIQTRGQL- 286
Q+G +++HC AG+GRTGV I +V RM + Q + +R +RP +QT +
Sbjct: 1834 QDGPISVHCSAGVGRTGVFITLSIVL-ERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQ 1892
Query: 287 LCVREFTQFL 296
C + ++L
Sbjct: 1893 FCYQAALEYL 1902
Score = 33.5 bits (75), Expect = 0.81
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 18/94 (19%)
Query: 211 WKDYGVASLTT----ILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRM--- 263
W D+GV T L VK G + +HC AG+GRTG C++V +
Sbjct: 1517 WPDHGVPEYPTPFLAFLRRVKTCN-PPDAGPIVVHCSAGVGRTG----CFIVIDAMLERI 1571
Query: 264 ----TAD--QAIIFVRAKRPNSIQTRGQLLCVRE 291
T D + +R++R +QT Q + E
Sbjct: 1572 KPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHE 1605
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,511,737
Number of Sequences: 37866
Number of extensions: 1623259
Number of successful extensions: 4703
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 102
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 4553
Number of HSP's gapped (non-prelim): 221
length of query: 806
length of database: 18,247,518
effective HSP length: 110
effective length of query: 696
effective length of database: 14,082,258
effective search space: 9801251568
effective search space used: 9801251568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.