BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|29544726 docking protein 5 [Homo sapiens] (306 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|29544726 docking protein 5 [Homo sapiens] 628 e-180 gi|47575849 docking protein 6 [Homo sapiens] 456 e-128 gi|20070302 docking protein 4 [Homo sapiens] 372 e-103 gi|4503357 docking protein 1 [Homo sapiens] 72 8e-13 gi|41406050 docking protein 2 [Homo sapiens] 67 2e-11 gi|221554537 docking protein 3 isoform 1 [Homo sapiens] 57 3e-08 gi|5730059 fibroblast growth factor receptor substrate 3 [Homo s... 54 1e-07 gi|110347414 fibroblast growth factor receptor substrate 2 [Homo... 50 2e-06 gi|110347408 fibroblast growth factor receptor substrate 2 [Homo... 50 2e-06 gi|5031805 insulin receptor substrate 1 [Homo sapiens] 48 9e-06 gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens] 41 0.001 gi|4504733 insulin receptor substrate 4 [Homo sapiens] 32 0.54 gi|30410805 CUB domain-containing protein 1 isoform 1 [Homo sapi... 32 0.92 gi|38683860 insulin receptor substrate 2 [Homo sapiens] 30 2.0 gi|156938343 talin 2 [Homo sapiens] 30 2.0 gi|71979663 growth factor receptor-bound protein 14 [Homo sapiens] 30 3.5 gi|149944424 1-aminocyclopropane-1-carboxylate synthase homolog ... 29 4.6 >gi|29544726 docking protein 5 [Homo sapiens] Length = 306 Score = 628 bits (1619), Expect = e-180 Identities = 306/306 (100%), Positives = 306/306 (100%) Query: 1 MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT 60 MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT Sbjct: 1 MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT 60 Query: 61 ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS 120 ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS Sbjct: 61 ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS 120 Query: 121 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP 180 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP Sbjct: 121 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP 180 Query: 181 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQS 240 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQS Sbjct: 181 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQS 240 Query: 241 VKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFP 300 VKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFP Sbjct: 241 VKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFP 300 Query: 301 AYRSEH 306 AYRSEH Sbjct: 301 AYRSEH 306 >gi|47575849 docking protein 6 [Homo sapiens] Length = 331 Score = 456 bits (1172), Expect = e-128 Identities = 216/307 (70%), Positives = 262/307 (85%), Gaps = 3/307 (0%) Query: 1 MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT 60 MASNFNDIVKQGYV+IRSR+LGI++RCWLVFKKASSKGP+RLEKF DE+AAYFR +HKVT Sbjct: 1 MASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVT 60 Query: 61 ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS 120 EL+N+KN+ RLP+ TKKHA+ I F+D+TSKTFACES+LEA+EWCK L MEC+GTR+NDIS Sbjct: 61 ELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDIS 120 Query: 121 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP 180 LGEPDLLA GV+REQ+ERFNVYLMP+PNLD++GEC +QIT+E I LWD+ N +VKL+ WP Sbjct: 121 LGEPDLLAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLWDIHNAKVKLVMWP 180 Query: 181 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERL-LQ 239 LS+LRRYGRD+TWFTFE+GRMC+TGEGLF FQTR+GE IYQKVHSA LAIAEQHERL L+ Sbjct: 181 LSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAIAEQHERLMLE 240 Query: 240 SVKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVS-SPLKLHRTET 298 + + LQ ++E +LS + LPRSAYW HITRQ+S G++Y LQ K+ R +T Sbjct: 241 MEQKARLQTSLTE-PMTLSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMSRAQT 299 Query: 299 FPAYRSE 305 FP+Y E Sbjct: 300 FPSYAPE 306 >gi|20070302 docking protein 4 [Homo sapiens] Length = 326 Score = 372 bits (956), Expect = e-103 Identities = 179/275 (65%), Positives = 225/275 (81%), Gaps = 2/275 (0%) Query: 1 MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT 60 MA+NF+DIVKQGYV+++SR+LGIY+RCWLVF+K+SSKGP+RLEK+ DE++ R KVT Sbjct: 1 MATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVT 60 Query: 61 ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS 120 E++NVK V RLPK TK+ A+ I F DD+++TF C+S+LEA+EW K L +EC+G+R+NDIS Sbjct: 61 EISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDIS 120 Query: 121 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP 180 LGEPDLLA GV+ EQ++RFNV+L+P PNLDV+GEC LQIT+E I LWD+ NPRVKL+SWP Sbjct: 121 LGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWP 180 Query: 181 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHER-LLQ 239 L +LRRYGRD T FTFEAGRMC+ GEGL+ FQT++GE IYQ+VHSA LAIAEQH+R LL+ Sbjct: 181 LCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLE 240 Query: 240 SVKNSMLQMKMSERAASLST-MVPLPRSAYWQHIT 273 KN L K +E + T LPRSAYW HIT Sbjct: 241 MEKNVRLLNKGTEHYSYPCTPTTMLPRSAYWHHIT 275 >gi|4503357 docking protein 1 [Homo sapiens] Length = 481 Score = 71.6 bits (174), Expect = 8e-13 Identities = 70/245 (28%), Positives = 105/245 (42%), Gaps = 28/245 (11%) Query: 9 VKQGYVRIRSRRLGI--YQRCWLVFKKASSKGPKRLEKFSDE-------RAAYFRCYHKV 59 V +G + ++S+R G +++ W V AS G RLE F + R + R KV Sbjct: 5 VMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRLDCKV 64 Query: 60 TELNNVKNVARLPKSTKKHAIGIYFNDDT---SKTFACESDLEADEWCKVLQMEC----- 111 L +VA + T F DT S A ++ A W + L Sbjct: 65 IRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSA-AWVQTLCRNAFPKGS 123 Query: 112 --VGTRINDISLGEPDLLATGVEREQSERFNVYLM-----PSPNLDVHGECALQITYEYI 164 + N L ++L + E ++ + +HG L++ E + Sbjct: 124 WTLAPTDNPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSYVLRVEAERL 183 Query: 165 CLWDV--QNPRVK-LISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQ 221 L V Q+ ++ L+SWP + LRRYGRD F+FEAGR C +G G F FQT G I+Q Sbjct: 184 TLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGNDIFQ 243 Query: 222 KVHSA 226 V +A Sbjct: 244 AVETA 248 >gi|41406050 docking protein 2 [Homo sapiens] Length = 412 Score = 67.4 bits (163), Expect = 2e-11 Identities = 39/110 (35%), Positives = 54/110 (49%), Gaps = 3/110 (2%) Query: 123 EPDLLATGVEREQSERFNVYLMP---SPNLDVHGECALQITYEYICLWDVQNPRVKLISW 179 E +L ++ V + F V + P S + G L+ + LW P +L W Sbjct: 135 ENELYSSAVTVGPHKEFAVTMRPTEASERCHLRGSYTLRAGESALELWGGPEPGTQLYDW 194 Query: 180 PLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALA 229 P LRR+GRD F+FEAGR C +GEG F F+TR G I+ + A A Sbjct: 195 PYRFLRRFGRDKVTFSFEAGRRCVSGEGNFEFETRQGNEIFLALEEAISA 244 >gi|221554537 docking protein 3 isoform 1 [Homo sapiens] Length = 496 Score = 56.6 bits (135), Expect = 3e-08 Identities = 34/84 (40%), Positives = 44/84 (52%), Gaps = 3/84 (3%) Query: 176 LISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHE 235 L SWP LR++G D F+FEAGR C +GEGLF F T + + V A AIA Q E Sbjct: 256 LYSWPYHFLRKFGSDKGVFSFEAGRRCHSGEGLFAFSTPCAPDLCRAV---AGAIARQRE 312 Query: 236 RLLQSVKNSMLQMKMSERAASLST 259 RL + + + + SL T Sbjct: 313 RLPELTRPQPCPLPRATSLPSLDT 336 >gi|5730059 fibroblast growth factor receptor substrate 3 [Homo sapiens] Length = 492 Score = 54.3 bits (129), Expect = 1e-07 Identities = 22/48 (45%), Positives = 32/48 (66%) Query: 173 RVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIY 220 R + + WP LRRYG D+ F+FE+GR C+TG+G+F F+ E I+ Sbjct: 51 RREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIF 98 >gi|110347414 fibroblast growth factor receptor substrate 2 [Homo sapiens] Length = 508 Score = 50.1 bits (118), Expect = 2e-06 Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 3/68 (4%) Query: 153 GECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQ 212 G +++T + L+ + VK W LRRYG D+ F+FE+GR C+TG+G+F F+ Sbjct: 34 GSGIMELTDTELILYTRKRDSVK---WHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFK 90 Query: 213 TRDGEAIY 220 E ++ Sbjct: 91 CARAEELF 98 >gi|110347408 fibroblast growth factor receptor substrate 2 [Homo sapiens] Length = 508 Score = 50.1 bits (118), Expect = 2e-06 Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 3/68 (4%) Query: 153 GECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQ 212 G +++T + L+ + VK W LRRYG D+ F+FE+GR C+TG+G+F F+ Sbjct: 34 GSGIMELTDTELILYTRKRDSVK---WHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFK 90 Query: 213 TRDGEAIY 220 E ++ Sbjct: 91 CARAEELF 98 >gi|5031805 insulin receptor substrate 1 [Homo sapiens] Length = 1242 Score = 48.1 bits (113), Expect = 9e-06 Identities = 66/301 (21%), Positives = 117/301 (38%), Gaps = 62/301 (20%) Query: 2 ASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVTE 61 + F+D+ K GY+R + +++R +++ + + GP RLE + +E+ + HK + Sbjct: 7 SDGFSDVRKVGYLR---KPKSMHKRFFVLRAASEAGGPARLEYYENEK----KWRHKSSA 59 Query: 62 ------LNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQM------ 109 L + N+ + S KH + +Y D+ A +S+ E D W + L Sbjct: 60 PKRSIPLESCFNINKRADSKNKHLVALYTRDEHF-AIAADSEAEQDSWYQALLQLHNRAK 118 Query: 110 ----------------ECVGTRINDISLGEP--DLLATGVEREQS--ERFNVYLMP---- 145 C G+ LGE DL V + E + V L P Sbjct: 119 GHHDGAAALGAGGGGGSCSGSS----GLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLG 174 Query: 146 -SPNL-DVHGECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCE 203 + NL ++ C T ++ L N + L +RR G +F E GR Sbjct: 175 QTKNLIGIYRLCLTSKTISFVKL----NSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAV 230 Query: 204 TGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKMSERAASLSTMVPL 263 TG G F Q D + Q +H L ++++ + S+ +++ S + + Sbjct: 231 TGPGEFWMQV-DDSVVAQNMHETIL-------EAMRAMSDEFRPRSKSQSSSNCSNPISV 282 Query: 264 P 264 P Sbjct: 283 P 283 >gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens] Length = 504 Score = 41.2 bits (95), Expect = 0.001 Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Query: 138 RFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFE 197 RF+V + P L+ G L + + + L P V W LS LRRYG + F FE Sbjct: 113 RFHVTVAPGTKLE-SGPATLHLCNDVLVLARDIPPAVTG-QWKLSDLRRYGAVPSGFIFE 170 Query: 198 AGRMCETGEGLFIFQTRDGEAI 219 G C G+F + +GE I Sbjct: 171 GGTRCGYWAGVFFLSSAEGEQI 192 >gi|4504733 insulin receptor substrate 4 [Homo sapiens] Length = 1257 Score = 32.3 bits (72), Expect = 0.54 Identities = 57/257 (22%), Positives = 95/257 (36%), Gaps = 44/257 (17%) Query: 7 DIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCY---------- 56 ++ K+GY+R + R + V K ++ P RLE + E A FR Sbjct: 78 EVCKRGYLRKQKHG----HRRYFVLKLETADAPARLEYY--ENARKFRHSVRAAAAAAAA 131 Query: 57 -------------HKVTELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEW 103 +V L +V++ + +H I ++ D+ A E++ E + W Sbjct: 132 AASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVA-ENESEQESW 190 Query: 104 CKVLQ---MECVGTRINDISL---GEPDLLATGVEREQ---SERFNVYLMP---SPNLDV 151 +L +E R + GEP LA E + + V + P ++ Sbjct: 191 YLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVKPRGLGHRKEL 250 Query: 152 HGECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIF 211 G L +T E + + N V + L ++RR G +F E GR G G Sbjct: 251 SGVFRLCLTDEEVVFVRL-NTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIGPGELWM 309 Query: 212 QTRDGEAIYQKVHSAAL 228 Q D + Q +H L Sbjct: 310 QV-DDCVVAQNMHELFL 325 >gi|30410805 CUB domain-containing protein 1 isoform 1 [Homo sapiens] Length = 836 Score = 31.6 bits (70), Expect = 0.92 Identities = 15/46 (32%), Positives = 22/46 (47%) Query: 167 WDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQ 212 WD P + +SW +S R T+F +G +C+TG I Q Sbjct: 564 WDRGLPSLTSVSWNISVPRDQVACLTFFKERSGVVCQTGRAFMIIQ 609 >gi|38683860 insulin receptor substrate 2 [Homo sapiens] Length = 1338 Score = 30.4 bits (67), Expect = 2.0 Identities = 21/82 (25%), Positives = 32/82 (39%), Gaps = 1/82 (1%) Query: 177 ISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHER 236 ++ L +RR G ++F E GR TG G Q D + Q +H L + + Sbjct: 238 VTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQA-DDSVVAQNIHETILEAMKALKE 296 Query: 237 LLQSVKNSMLQMKMSERAASLS 258 L + S Q S +S Sbjct: 297 LFEFRPRSKSQSSGSSATHPIS 318 >gi|156938343 talin 2 [Homo sapiens] Length = 2542 Score = 30.4 bits (67), Expect = 2.0 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Query: 157 LQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDG 216 L IT + + D + V L WPL+ ++R+ FT + G E E + QT +G Sbjct: 333 LGITKDSVMRVDEKTKEV-LQEWPLTTVKRWAASPKSFTLDFG---EYQESYYSVQTTEG 388 Query: 217 EAIYQKV 223 E I Q + Sbjct: 389 EQISQLI 395 >gi|71979663 growth factor receptor-bound protein 14 [Homo sapiens] Length = 540 Score = 29.6 bits (65), Expect = 3.5 Identities = 13/34 (38%), Positives = 20/34 (58%) Query: 74 STKKHAIGIYFNDDTSKTFACESDLEADEWCKVL 107 S KK I +Y D+TS+ SD+ A + C++L Sbjct: 104 SRKKQVIKVYSEDETSRALDVPSDITARDVCQLL 137 >gi|149944424 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like [Homo sapiens] Length = 568 Score = 29.3 bits (64), Expect = 4.6 Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 3/52 (5%) Query: 213 TRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKMSERAASLSTMVPLP 264 +R G ++ ++ H+ A+ +HE LL + M+ + S A+ L VPLP Sbjct: 49 SRQGLSLEERRHTEAIC---EHEALLSRLICRMINLLQSGAASGLELQVPLP 97 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.133 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,954,688 Number of Sequences: 37866 Number of extensions: 447847 Number of successful extensions: 921 Number of sequences better than 10.0: 17 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 906 Number of HSP's gapped (non-prelim): 18 length of query: 306 length of database: 18,247,518 effective HSP length: 102 effective length of query: 204 effective length of database: 14,385,186 effective search space: 2934577944 effective search space used: 2934577944 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.