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Search of human proteins with 29469071
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29469071 Rho GTPase-activating protein isoform 2 [Homo
sapiens]
(1738 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 3527 0.0
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 3527 0.0
gi|23510413 sorting nexin 26 [Homo sapiens] 396 e-110
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 354 4e-97
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap... 346 1e-94
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 346 1e-94
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 126 2e-28
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 126 2e-28
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 121 5e-27
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 121 5e-27
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 120 2e-26
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 120 2e-26
gi|188497642 ARHGAP15 [Homo sapiens] 119 3e-26
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 117 7e-26
gi|229094128 active breakpoint cluster region-related protein i... 111 7e-24
gi|38679957 active breakpoint cluster region-related protein is... 111 7e-24
gi|38679954 active breakpoint cluster region-related protein is... 111 7e-24
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 111 7e-24
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 111 7e-24
gi|54860079 nadrin isoform 1 [Homo sapiens] 108 6e-23
gi|54860105 nadrin isoform 2 [Homo sapiens] 108 6e-23
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 103 1e-21
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 102 2e-21
gi|208022687 GTPase regulator associated with the focal adhesion... 101 6e-21
gi|7662208 GTPase regulator associated with the focal adhesion k... 101 6e-21
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 97 1e-19
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 97 1e-19
gi|156119615 myosin IXA [Homo sapiens] 97 2e-19
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 95 5e-19
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 95 7e-19
>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
Length = 2087
Score = 3527 bits (9145), Expect = 0.0
Identities = 1738/1738 (100%), Positives = 1738/1738 (100%)
Query: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS 60
MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS
Sbjct: 350 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS 409
Query: 61 GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA 120
GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA
Sbjct: 410 GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA 469
Query: 121 VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL 180
VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL
Sbjct: 470 VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL 529
Query: 181 LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL 240
LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL
Sbjct: 530 LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL 589
Query: 241 VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ 300
VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ
Sbjct: 590 VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ 649
Query: 301 NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES 360
NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES
Sbjct: 650 NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES 709
Query: 361 LTSLHAVDGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHI 420
LTSLHAVDGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHI
Sbjct: 710 LTSLHAVDGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHI 769
Query: 421 PALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPKAESECLESGASFLDSPGYSKDKP 480
PALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPKAESECLESGASFLDSPGYSKDKP
Sbjct: 770 PALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPKAESECLESGASFLDSPGYSKDKP 829
Query: 481 SANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVY 540
SANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVY
Sbjct: 830 SANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVY 889
Query: 541 AFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDAT 600
AFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDAT
Sbjct: 890 AFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDAT 949
Query: 601 NRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVELPGKEDQSVSSSQSKAVASGQTQ 660
NRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVELPGKEDQSVSSSQSKAVASGQTQ
Sbjct: 950 NRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVELPGKEDQSVSSSQSKAVASGQTQ 1009
Query: 661 TGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGTSQAGY 720
TGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGTSQAGY
Sbjct: 1010 TGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGTSQAGY 1069
Query: 721 TNYGDIAVATTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGD 780
TNYGDIAVATTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGD
Sbjct: 1070 TNYGDIAVATTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGD 1129
Query: 781 PTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGK 840
PTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGK
Sbjct: 1130 PTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGK 1189
Query: 841 NSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDKIYPPS 900
NSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDKIYPPS
Sbjct: 1190 NSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDKIYPPS 1249
Query: 901 GSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPP 960
GSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPP
Sbjct: 1250 GSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPP 1309
Query: 961 PSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPERPPEPRAMDDPASAFISDSGAAA 1020
PSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPERPPEPRAMDDPASAFISDSGAAA
Sbjct: 1310 PSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPERPPEPRAMDDPASAFISDSGAAA 1369
Query: 1021 AQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAHPCGFPAPLPPTRMMESKMIAAIHS 1080
AQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAHPCGFPAPLPPTRMMESKMIAAIHS
Sbjct: 1370 AQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAHPCGFPAPLPPTRMMESKMIAAIHS 1429
Query: 1081 SSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKTVYSSFARPDVTTEPFGPD 1140
SSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKTVYSSFARPDVTTEPFGPD
Sbjct: 1430 SSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKTVYSSFARPDVTTEPFGPD 1489
Query: 1141 NCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEPPASMGLRYNTYVAPGRNASGHHS 1200
NCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEPPASMGLRYNTYVAPGRNASGHHS
Sbjct: 1490 NCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEPPASMGLRYNTYVAPGRNASGHHS 1549
Query: 1201 KPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQSLHAPPSSMIRSVPISRTEVPPDDE 1260
KPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQSLHAPPSSMIRSVPISRTEVPPDDE
Sbjct: 1550 KPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQSLHAPPSSMIRSVPISRTEVPPDDE 1609
Query: 1261 PAYCPRPLYQYKPYQSSQARSDYHVTQLQPYFENGRVHYRYSPYSSSSSSYYSPDGALCD 1320
PAYCPRPLYQYKPYQSSQARSDYHVTQLQPYFENGRVHYRYSPYSSSSSSYYSPDGALCD
Sbjct: 1610 PAYCPRPLYQYKPYQSSQARSDYHVTQLQPYFENGRVHYRYSPYSSSSSSYYSPDGALCD 1669
Query: 1321 VDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYAGLAPRPRANVTGYFSPNDHNVVSM 1380
VDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYAGLAPRPRANVTGYFSPNDHNVVSM
Sbjct: 1670 VDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYAGLAPRPRANVTGYFSPNDHNVVSM 1729
Query: 1381 PPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKVKGPVMSQYDNMTPAVQDDLGGIYV 1440
PPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKVKGPVMSQYDNMTPAVQDDLGGIYV
Sbjct: 1730 PPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKVKGPVMSQYDNMTPAVQDDLGGIYV 1789
Query: 1441 IHLRSKSDPGKTGLLSVAEGKESRHAAKAISPEGEDRFYRRHPEAEMDRAHHHGGHGSTQ 1500
IHLRSKSDPGKTGLLSVAEGKESRHAAKAISPEGEDRFYRRHPEAEMDRAHHHGGHGSTQ
Sbjct: 1790 IHLRSKSDPGKTGLLSVAEGKESRHAAKAISPEGEDRFYRRHPEAEMDRAHHHGGHGSTQ 1849
Query: 1501 PEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASHRQFCESKNGPPYPQGAGQLDYGSK 1560
PEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASHRQFCESKNGPPYPQGAGQLDYGSK
Sbjct: 1850 PEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASHRQFCESKNGPPYPQGAGQLDYGSK 1909
Query: 1561 GIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLSKEMERPWVRQPSAPEKHSRDCYKE 1620
GIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLSKEMERPWVRQPSAPEKHSRDCYKE
Sbjct: 1910 GIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLSKEMERPWVRQPSAPEKHSRDCYKE 1969
Query: 1621 EEHLTQSIVPPPKPERSHSLKLHHTQNVERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDY 1680
EEHLTQSIVPPPKPERSHSLKLHHTQNVERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDY
Sbjct: 1970 EEHLTQSIVPPPKPERSHSLKLHHTQNVERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDY 2029
Query: 1681 HSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALGQGAFLPAELSLQHPETQIHAE 1738
HSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALGQGAFLPAELSLQHPETQIHAE
Sbjct: 2030 HSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALGQGAFLPAELSLQHPETQIHAE 2087
>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
Length = 1738
Score = 3527 bits (9145), Expect = 0.0
Identities = 1738/1738 (100%), Positives = 1738/1738 (100%)
Query: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS 60
MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS
Sbjct: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS 60
Query: 61 GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA 120
GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA
Sbjct: 61 GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA 120
Query: 121 VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL 180
VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL
Sbjct: 121 VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL 180
Query: 181 LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL 240
LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL
Sbjct: 181 LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL 240
Query: 241 VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ 300
VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ
Sbjct: 241 VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ 300
Query: 301 NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES 360
NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES
Sbjct: 301 NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES 360
Query: 361 LTSLHAVDGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHI 420
LTSLHAVDGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHI
Sbjct: 361 LTSLHAVDGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHI 420
Query: 421 PALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPKAESECLESGASFLDSPGYSKDKP 480
PALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPKAESECLESGASFLDSPGYSKDKP
Sbjct: 421 PALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPKAESECLESGASFLDSPGYSKDKP 480
Query: 481 SANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVY 540
SANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVY
Sbjct: 481 SANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVY 540
Query: 541 AFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDAT 600
AFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDAT
Sbjct: 541 AFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDAT 600
Query: 601 NRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVELPGKEDQSVSSSQSKAVASGQTQ 660
NRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVELPGKEDQSVSSSQSKAVASGQTQ
Sbjct: 601 NRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVELPGKEDQSVSSSQSKAVASGQTQ 660
Query: 661 TGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGTSQAGY 720
TGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGTSQAGY
Sbjct: 661 TGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGTSQAGY 720
Query: 721 TNYGDIAVATTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGD 780
TNYGDIAVATTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGD
Sbjct: 721 TNYGDIAVATTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGD 780
Query: 781 PTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGK 840
PTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGK
Sbjct: 781 PTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGK 840
Query: 841 NSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDKIYPPS 900
NSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDKIYPPS
Sbjct: 841 NSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDKIYPPS 900
Query: 901 GSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPP 960
GSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPP
Sbjct: 901 GSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPP 960
Query: 961 PSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPERPPEPRAMDDPASAFISDSGAAA 1020
PSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPERPPEPRAMDDPASAFISDSGAAA
Sbjct: 961 PSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPERPPEPRAMDDPASAFISDSGAAA 1020
Query: 1021 AQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAHPCGFPAPLPPTRMMESKMIAAIHS 1080
AQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAHPCGFPAPLPPTRMMESKMIAAIHS
Sbjct: 1021 AQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAHPCGFPAPLPPTRMMESKMIAAIHS 1080
Query: 1081 SSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKTVYSSFARPDVTTEPFGPD 1140
SSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKTVYSSFARPDVTTEPFGPD
Sbjct: 1081 SSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKTVYSSFARPDVTTEPFGPD 1140
Query: 1141 NCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEPPASMGLRYNTYVAPGRNASGHHS 1200
NCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEPPASMGLRYNTYVAPGRNASGHHS
Sbjct: 1141 NCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEPPASMGLRYNTYVAPGRNASGHHS 1200
Query: 1201 KPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQSLHAPPSSMIRSVPISRTEVPPDDE 1260
KPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQSLHAPPSSMIRSVPISRTEVPPDDE
Sbjct: 1201 KPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQSLHAPPSSMIRSVPISRTEVPPDDE 1260
Query: 1261 PAYCPRPLYQYKPYQSSQARSDYHVTQLQPYFENGRVHYRYSPYSSSSSSYYSPDGALCD 1320
PAYCPRPLYQYKPYQSSQARSDYHVTQLQPYFENGRVHYRYSPYSSSSSSYYSPDGALCD
Sbjct: 1261 PAYCPRPLYQYKPYQSSQARSDYHVTQLQPYFENGRVHYRYSPYSSSSSSYYSPDGALCD 1320
Query: 1321 VDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYAGLAPRPRANVTGYFSPNDHNVVSM 1380
VDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYAGLAPRPRANVTGYFSPNDHNVVSM
Sbjct: 1321 VDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYAGLAPRPRANVTGYFSPNDHNVVSM 1380
Query: 1381 PPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKVKGPVMSQYDNMTPAVQDDLGGIYV 1440
PPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKVKGPVMSQYDNMTPAVQDDLGGIYV
Sbjct: 1381 PPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKVKGPVMSQYDNMTPAVQDDLGGIYV 1440
Query: 1441 IHLRSKSDPGKTGLLSVAEGKESRHAAKAISPEGEDRFYRRHPEAEMDRAHHHGGHGSTQ 1500
IHLRSKSDPGKTGLLSVAEGKESRHAAKAISPEGEDRFYRRHPEAEMDRAHHHGGHGSTQ
Sbjct: 1441 IHLRSKSDPGKTGLLSVAEGKESRHAAKAISPEGEDRFYRRHPEAEMDRAHHHGGHGSTQ 1500
Query: 1501 PEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASHRQFCESKNGPPYPQGAGQLDYGSK 1560
PEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASHRQFCESKNGPPYPQGAGQLDYGSK
Sbjct: 1501 PEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASHRQFCESKNGPPYPQGAGQLDYGSK 1560
Query: 1561 GIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLSKEMERPWVRQPSAPEKHSRDCYKE 1620
GIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLSKEMERPWVRQPSAPEKHSRDCYKE
Sbjct: 1561 GIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLSKEMERPWVRQPSAPEKHSRDCYKE 1620
Query: 1621 EEHLTQSIVPPPKPERSHSLKLHHTQNVERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDY 1680
EEHLTQSIVPPPKPERSHSLKLHHTQNVERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDY
Sbjct: 1621 EEHLTQSIVPPPKPERSHSLKLHHTQNVERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDY 1680
Query: 1681 HSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALGQGAFLPAELSLQHPETQIHAE 1738
HSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALGQGAFLPAELSLQHPETQIHAE
Sbjct: 1681 HSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALGQGAFLPAELSLQHPETQIHAE 1738
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 396 bits (1018), Expect = e-110
Identities = 216/372 (58%), Positives = 272/372 (73%), Gaps = 31/372 (8%)
Query: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS 60
M+SRP++Q+L+QRGIL++RVFGCDLGEHL NSG +VPQVL+ C+ FIE +G+VDGIYRLS
Sbjct: 293 MRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVDGIYRLS 352
Query: 61 GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA 120
GV+SNIQRLRHEFDSE +P+L+ ++QDIHSV SLCKLYFRELPNPLLTYQLY KFS+A
Sbjct: 353 GVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEA 412
Query: 121 VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL 180
+S +EERL+++HDVIQQLPPPHYRTLE+L+RHL+ +A + + T+MHA+NLAIVWAPNL
Sbjct: 413 MSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNL 472
Query: 181 LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQE--GAASLSRPKS 238
LRS ++ES G AAF EVR+QSVVVEF+L HVDVLFS + A + G L RPKS
Sbjct: 473 LRSMELESVGMGGAAAFREVRVQSVVVEFLLTHVDVLFSDTFTSAGLDPAGRCLLPRPKS 532
Query: 239 LLVSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKR 298
L S PST+LLTLEEAQARTQ ++ +P TE + PA+ P ER++
Sbjct: 533 LAGSCPSTRLLTLEEAQARTQGRLGTP--TEP---TTPKAPAS-----------PAERRK 576
Query: 299 PQ--NKMKKSPVGSWRSFFNLGKSSSVSKRK----LQRNESEPSEMKAMALKGGRAEG-T 351
+ K +K SW++FF LG+ SV ++K L + P G R + T
Sbjct: 577 GERGEKQRKPGGSSWKTFFALGRGPSVPRKKPLPWLGGTRAPPQP------SGSRPDTVT 630
Query: 352 LRSAKSEESLTS 363
LRSAKSEESL+S
Sbjct: 631 LRSAKSEESLSS 642
Score = 43.1 bits (100), Expect = 0.002
Identities = 19/26 (73%), Positives = 22/26 (84%)
Query: 683 PPPPPKNVARMLALALAESAQQASTQ 708
PPPPPKN AR++ALALAE AQQ + Q
Sbjct: 728 PPPPPKNPARLMALALAERAQQVAEQ 753
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 354 bits (909), Expect = 4e-97
Identities = 290/839 (34%), Positives = 419/839 (49%), Gaps = 97/839 (11%)
Query: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS 60
MK++ KQKLK++G FGCDL E+L +SG +VP VL+SC FIE +GIVDGIYRLS
Sbjct: 1 MKNKGAKQKLKRKGAAS--AFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLS 58
Query: 61 GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA 120
GV SNIQRLR EF S+ PDLT+E Y+QDIH VGSLCKLYFRELPNPLLTY+LYEKF++A
Sbjct: 59 GVTSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEA 118
Query: 121 VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL 180
VS +E +L +I +VIQ+LPP HYRTLE+L+RHL+ +A + S TNMHA+NLA+VWAPNL
Sbjct: 119 VSHCPEEGQLARIQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNL 178
Query: 181 LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRP--KS 238
LRSK+IE+ +G AAF+ VR+Q VV+EFILNHVD +F+ +++ +RP KS
Sbjct: 179 LRSKEIEATGCNGDAAFLAVRVQQVVIEFILNHVDQIFNNGAPGSLENDE---NRPIMKS 235
Query: 239 LLVSSPS--TKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLER 296
L + + S KL++LEEAQAR+ A N P E + + E + FHT++E P +
Sbjct: 236 LTLPALSLPMKLVSLEEAQARSLA-TNHPARKERRENSLPEIVPPMGTLFHTVLELPDNK 294
Query: 297 KRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAK 356
++ +K KK W+S FNLG+S S SK KL RN S + ++++ + T+R AK
Sbjct: 295 RKLSSKSKK-----WKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVE----KATIRPAK 345
Query: 357 SEESLTSLHAVDGDSKLFRPRRPRSSSDALSAS-FNGEMLGNRCNSYDNLPHDNESEEEG 415
S +SL S+ ++K R + + A+ + G+ C D + E +EG
Sbjct: 346 SMDSLCSVPVEGKETKGNFNRTVTTGGFFIPATKMHSTGTGSSC---DLTKQEGEWGQEG 402
Query: 416 GLLHIPALMSPHSAE---DVDLSPPDIGVASLDFDPMSFQCSPPKAESECLESGASFLDS 472
P AE DV + A P + P + E ++ L
Sbjct: 403 ---------MPPGAEGGFDVSSDRSHLQGAQARPPPEQLKVFRPVEDPESEQTAPKMLGM 453
Query: 473 PGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPS 532
S D PS K T SS Q S + + E + L +S +S P
Sbjct: 454 FYTSNDSPS---KSVFT-SSLFQMEPSPRNQRKALNISEPFAVSVPLRVSAVISTNSTPC 509
Query: 533 SFTEKVVYAFS---------------PKIGRKL-SKSPSMSISEPISVTLPPRVSEVIGT 576
K + + S P+ + L +++ + S+ + + V E GT
Sbjct: 510 RTPPKELQSLSSLEEFSFHGSESGGWPEEEKPLGAETSAASVPKKAGLEDAKAVPEAPGT 569
Query: 577 V--SNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYE------SEVQPL 628
V S +Q + +K E +++ ++ K E V +E E S +Q
Sbjct: 570 VECSKGLSQEPGAHLEEKKTPESSLSSQHLNELEKRPNPEKVVEEGREAGEMESSTLQES 629
Query: 629 DQVAAEEVELPGKEDQSVSSS--------QSKAVASGQTQTG----AVTHDPPQDSVPVS 676
+ AE V L ++ ++++ + K + S + + A+ P Q + S
Sbjct: 630 PRARAEAVLLHEMDEDDLANALIWPEIQQELKIIESEEELSSLPPPALKTSPIQPILESS 689
Query: 677 SVSLIPPPPP--------PKNVARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAV 728
IP PP P V+ L + + A Q STQ G S A +
Sbjct: 690 LGPFIPSEPPGSLPCGSFPAPVSTPLEVWTRDPANQ-STQ-----GASTAASREKPE--- 740
Query: 729 ATTEDNLSSSYSAVA-LDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNT 786
E L +++A L+ F+ P Q ++ PGN PLP P +T
Sbjct: 741 --PEQGLHPDLASLAPLEIVPFEKASP--QATVEVGGPGNLSPPLPPAPPPPTPLEEST 795
>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
sapiens]
Length = 890
Score = 346 bits (888), Expect = 1e-94
Identities = 200/383 (52%), Positives = 256/383 (66%), Gaps = 31/383 (8%)
Query: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS 60
MKSR QK K++G KERVFGCDL EHL +SG EVPQVL+SC F+E YG+VDGIYRLS
Sbjct: 1 MKSR---QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLS 57
Query: 61 GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA 120
GV+SNIQ+LR EF+SE PDL ++ Y+QDIH V SLCK YFRELP+PLLTY+LY+KF++A
Sbjct: 58 GVSSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEA 117
Query: 121 VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL 180
V + ERL+KI +V+++LP P+YRTLEFLMRHL +A + + TNMHA+NLAIVWAPNL
Sbjct: 118 VGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNL 177
Query: 181 LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL 240
LRSK IE++ F+GTAAFMEVR+QS+VVEFIL HVD LF G A S +S
Sbjct: 178 LRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGG--------AALSGGEVESGW 229
Query: 241 VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ 300
S P T+ E + P + ++ G+GP ++ +HTIIE +++
Sbjct: 230 RSLPGTRASGSPEDLMPRPLPYHLPSI-----LQAGDGPPQMR-PYHTIIEIAEHKRKGS 283
Query: 301 NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES 360
K++K WRS FNLG+S +KRKL R +E E K+ +GTLR AKS +S
Sbjct: 284 LKVRK-----WRSIFNLGRSGHETKRKLPRG-AEDREDKS-------NKGTLRPAKSMDS 330
Query: 361 LT-SLHAVDGDSKLFRPRRPRSS 382
L+ + A D L P PR S
Sbjct: 331 LSAAAGASDEPEGLVGPSSPRPS 353
Score = 32.3 bits (72), Expect = 4.1
Identities = 28/113 (24%), Positives = 40/113 (35%), Gaps = 9/113 (7%)
Query: 920 ATAQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAAT 979
A Q ++A W+V E + R P PP P + E P
Sbjct: 644 ALGQGGEEQACWEVGEDKQAEPGGRLDI-REEAEGTPQPPQPEEMEPEGQPSPDGCLCPC 702
Query: 980 NIGLNNSH--------KVQGVVPVPERPPEPRAMDDPASAFISDSGAAAAQCP 1024
++GL +VQ V VP PP+P+ P++ A A CP
Sbjct: 703 SLGLGGVGMRLASTLVQVQQVRSVPVVPPKPQFAKMPSAMCSKIHVAPANPCP 755
>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
sapiens]
Length = 1101
Score = 346 bits (888), Expect = 1e-94
Identities = 200/383 (52%), Positives = 256/383 (66%), Gaps = 31/383 (8%)
Query: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS 60
MKSR QK K++G KERVFGCDL EHL +SG EVPQVL+SC F+E YG+VDGIYRLS
Sbjct: 1 MKSR---QKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLS 57
Query: 61 GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA 120
GV+SNIQ+LR EF+SE PDL ++ Y+QDIH V SLCK YFRELP+PLLTY+LY+KF++A
Sbjct: 58 GVSSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEA 117
Query: 121 VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL 180
V + ERL+KI +V+++LP P+YRTLEFLMRHL +A + + TNMHA+NLAIVWAPNL
Sbjct: 118 VGVQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNL 177
Query: 181 LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL 240
LRSK IE++ F+GTAAFMEVR+QS+VVEFIL HVD LF G A S +S
Sbjct: 178 LRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGG--------AALSGGEVESGW 229
Query: 241 VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ 300
S P T+ E + P + ++ G+GP ++ +HTIIE +++
Sbjct: 230 RSLPGTRASGSPEDLMPRPLPYHLPSI-----LQAGDGPPQMR-PYHTIIEIAEHKRKGS 283
Query: 301 NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES 360
K++K WRS FNLG+S +KRKL R +E E K+ +GTLR AKS +S
Sbjct: 284 LKVRK-----WRSIFNLGRSGHETKRKLPRG-AEDREDKS-------NKGTLRPAKSMDS 330
Query: 361 LT-SLHAVDGDSKLFRPRRPRSS 382
L+ + A D L P PR S
Sbjct: 331 LSAAAGASDEPEGLVGPSSPRPS 353
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 126 bits (317), Expect = 2e-28
Identities = 72/219 (32%), Positives = 120/219 (54%), Gaps = 8/219 (3%)
Query: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRL 59
++ RPT Q L+++G +K++VFGC L VP+ +Q C +E G+ +DG+YR+
Sbjct: 307 LQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRI 366
Query: 60 SGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSD 119
SG + IQ+LR++ D + DL + +D+H + KL+FRELP PL + + +F
Sbjct: 367 SGNLATIQKLRYKVDHDERLDLDDGRW-EDVHVITGALKLFFRELPEPLFPFSHFRQFIA 425
Query: 120 AVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPN 179
A+ R + D+++ LP P++ TL L +HL + ++ M +++AIV+ P
Sbjct: 426 AIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPT 485
Query: 180 LLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLF 218
LLR + E T+ M + Q+ VVE IL +F
Sbjct: 486 LLRPEVEE------TSMPMTMVFQNQVVELILQQCADIF 518
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 126 bits (317), Expect = 2e-28
Identities = 72/219 (32%), Positives = 120/219 (54%), Gaps = 8/219 (3%)
Query: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRL 59
++ RPT Q L+++G +K++VFGC L VP+ +Q C +E G+ +DG+YR+
Sbjct: 334 LQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRI 393
Query: 60 SGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSD 119
SG + IQ+LR++ D + DL + +D+H + KL+FRELP PL + + +F
Sbjct: 394 SGNLATIQKLRYKVDHDERLDLDDGRW-EDVHVITGALKLFFRELPEPLFPFSHFRQFIA 452
Query: 120 AVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPN 179
A+ R + D+++ LP P++ TL L +HL + ++ M +++AIV+ P
Sbjct: 453 AIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPT 512
Query: 180 LLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLF 218
LLR + E T+ M + Q+ VVE IL +F
Sbjct: 513 LLRPEVEE------TSMPMTMVFQNQVVELILQQCADIF 545
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 121 bits (304), Expect = 5e-27
Identities = 69/203 (33%), Positives = 117/203 (57%), Gaps = 8/203 (3%)
Query: 18 ERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFDSE 76
++V+ CDL + + P V+ C IE G+ +G+YR+SG + I+ ++ FD +
Sbjct: 263 KKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRD 322
Query: 77 -HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHD 135
D++ Y +DI+ + KLYFR+LP PL+TY Y KF ++ +E+L +H+
Sbjct: 323 GEKADISVNMY-EDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHE 381
Query: 136 VIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTA 195
++ LPP H TL +LM HL + + M+A+NL IV+ P L+RS ++++ A
Sbjct: 382 ALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDA-----MA 436
Query: 196 AFMEVRIQSVVVEFILNHVDVLF 218
A ++R Q +VVE ++ + D+LF
Sbjct: 437 ALNDIRYQRLVVELLIKNEDILF 459
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 121 bits (304), Expect = 5e-27
Identities = 69/203 (33%), Positives = 117/203 (57%), Gaps = 8/203 (3%)
Query: 18 ERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFDSE 76
++V+ CDL + + P V+ C IE G+ +G+YR+SG + I+ ++ FD +
Sbjct: 237 KKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRD 296
Query: 77 -HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHD 135
D++ Y +DI+ + KLYFR+LP PL+TY Y KF ++ +E+L +H+
Sbjct: 297 GEKADISVNMY-EDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHE 355
Query: 136 VIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTA 195
++ LPP H TL +LM HL + + M+A+NL IV+ P L+RS ++++ A
Sbjct: 356 ALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDA-----MA 410
Query: 196 AFMEVRIQSVVVEFILNHVDVLF 218
A ++R Q +VVE ++ + D+LF
Sbjct: 411 ALNDIRYQRLVVELLIKNEDILF 433
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 120 bits (300), Expect = 2e-26
Identities = 70/203 (34%), Positives = 112/203 (55%), Gaps = 8/203 (3%)
Query: 18 ERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIV-DGIYRLSGVASNIQRLRHEFDSE 76
++V+ CDL + + P V+ C IE G+ +G+YR+SG +I+ ++ FD +
Sbjct: 272 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 331
Query: 77 -HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHD 135
D++ Y DI+ + KLYFR+LP P++TY Y KF DA + +ERL +H+
Sbjct: 332 GEKADISANVY-PDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE 390
Query: 136 VIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTA 195
V+ LPP HY TL +LM HL + M+A+NL IV+ P L+R + S
Sbjct: 391 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE-----DSTLT 445
Query: 196 AFMEVRIQSVVVEFILNHVDVLF 218
++R Q ++V+ ++ + DVLF
Sbjct: 446 TLHDMRYQKLIVQILIENEDVLF 468
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 120 bits (300), Expect = 2e-26
Identities = 70/203 (34%), Positives = 112/203 (55%), Gaps = 8/203 (3%)
Query: 18 ERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIV-DGIYRLSGVASNIQRLRHEFDSE 76
++V+ CDL + + P V+ C IE G+ +G+YR+SG +I+ ++ FD +
Sbjct: 136 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 195
Query: 77 -HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHD 135
D++ Y DI+ + KLYFR+LP P++TY Y KF DA + +ERL +H+
Sbjct: 196 GEKADISANVY-PDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE 254
Query: 136 VIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTA 195
V+ LPP HY TL +LM HL + M+A+NL IV+ P L+R + S
Sbjct: 255 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE-----DSTLT 309
Query: 196 AFMEVRIQSVVVEFILNHVDVLF 218
++R Q ++V+ ++ + DVLF
Sbjct: 310 TLHDMRYQKLIVQILIENEDVLF 332
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 119 bits (297), Expect = 3e-26
Identities = 69/216 (31%), Positives = 120/216 (55%), Gaps = 8/216 (3%)
Query: 4 RPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGV 62
RP+ + L+++G++K+++FG L + VP ++ C +E+ G+ VDGIYR+SG
Sbjct: 262 RPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGN 321
Query: 63 ASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVS 122
+ IQ+LR + E +L + +DIH V K++FRELP PL Y +E+F +A+
Sbjct: 322 LATIQKLRFIVNQEEKLNLDDSQW-EDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIK 380
Query: 123 AATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLR 182
+ R+ + ++Q+LPPP+ T++ L HL+ + S M ++L IV+ P LLR
Sbjct: 381 KQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLR 440
Query: 183 SKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLF 218
++ +G A V Q+ + E +L+ +F
Sbjct: 441 AEN-----ETGNMAIHMV-YQNQIAELMLSEYSKIF 470
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 117 bits (294), Expect = 7e-26
Identities = 70/216 (32%), Positives = 121/216 (56%), Gaps = 9/216 (4%)
Query: 4 RPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGV 62
RPT Q ++++G +K++VFG +L VP+ ++ C +E +G+ +DGIYR+SG
Sbjct: 637 RPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGN 696
Query: 63 ASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVS 122
+ IQ+LR + + DL + +DIH + K++FRELP PL T+ + F +A+
Sbjct: 697 LAVIQKLRFAVNHDEKLDLNDSKW-EDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK 755
Query: 123 AATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLR 182
+R+ + D+I+QLP P+ T++ L RHL + + M +++AIV+ P LL+
Sbjct: 756 QEP-RQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLK 814
Query: 183 SKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLF 218
++ +G A V Q+ +VE IL + +F
Sbjct: 815 PEK-----ETGNIAVHTV-YQNQIVELILLELSSIF 844
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 111 bits (277), Expect = 7e-24
Identities = 75/223 (33%), Positives = 119/223 (53%), Gaps = 13/223 (5%)
Query: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRL 59
+K P+K KQ G VFG + +VP +++ C +E+ GI + GIYR+
Sbjct: 587 LKRTPSK---KQTG-----VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRI 638
Query: 60 SGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSD 119
SGVA++IQ L+ FD+ + D+ DI+++ KLYFRELP PLLT +LY F +
Sbjct: 639 SGVATDIQALKAVFDANN-KDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFME 697
Query: 120 AVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPN 179
++ + + + +++ LP P+ T FL+ HL +A+ I M NLA V+ P
Sbjct: 698 GIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPT 757
Query: 180 LLRSKQIESACFSGTAAFM---EVRIQSVVVEFILNHVDVLFS 219
LLR ++ES +AA + +V Q V+ + L H + F+
Sbjct: 758 LLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 800
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 111 bits (277), Expect = 7e-24
Identities = 75/223 (33%), Positives = 119/223 (53%), Gaps = 13/223 (5%)
Query: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRL 59
+K P+K KQ G VFG + +VP +++ C +E+ GI + GIYR+
Sbjct: 633 LKRTPSK---KQTG-----VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRI 684
Query: 60 SGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSD 119
SGVA++IQ L+ FD+ + D+ DI+++ KLYFRELP PLLT +LY F +
Sbjct: 685 SGVATDIQALKAVFDANN-KDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFME 743
Query: 120 AVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPN 179
++ + + + +++ LP P+ T FL+ HL +A+ I M NLA V+ P
Sbjct: 744 GIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPT 803
Query: 180 LLRSKQIESACFSGTAAFM---EVRIQSVVVEFILNHVDVLFS 219
LLR ++ES +AA + +V Q V+ + L H + F+
Sbjct: 804 LLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 846
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 111 bits (277), Expect = 7e-24
Identities = 75/223 (33%), Positives = 119/223 (53%), Gaps = 13/223 (5%)
Query: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRL 59
+K P+K KQ G VFG + +VP +++ C +E+ GI + GIYR+
Sbjct: 596 LKRTPSK---KQTG-----VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRI 647
Query: 60 SGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSD 119
SGVA++IQ L+ FD+ + D+ DI+++ KLYFRELP PLLT +LY F +
Sbjct: 648 SGVATDIQALKAVFDANN-KDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFME 706
Query: 120 AVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPN 179
++ + + + +++ LP P+ T FL+ HL +A+ I M NLA V+ P
Sbjct: 707 GIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPT 766
Query: 180 LLRSKQIESACFSGTAAFM---EVRIQSVVVEFILNHVDVLFS 219
LLR ++ES +AA + +V Q V+ + L H + F+
Sbjct: 767 LLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 809
>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
sapiens]
Length = 731
Score = 111 bits (277), Expect = 7e-24
Identities = 69/201 (34%), Positives = 103/201 (51%), Gaps = 20/201 (9%)
Query: 4 RPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGV 62
RP Q L++RG+L+++VFGC L G VP L+ C A +++ G+ VDGIYR+SG
Sbjct: 504 RPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGN 563
Query: 63 ASNIQRLRHEFDSEHVP------------------DLTKEPYVQDIHSVGSLCKLYFREL 104
+ +Q+LR D E DL + DIH V KL+ REL
Sbjct: 564 LAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEW-DDIHVVTGALKLFLREL 622
Query: 105 PNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSI 164
P PL+ L F A++ + E+ L +I ++I +P P++ TL +L+ HL + +
Sbjct: 623 PQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDK 682
Query: 165 TNMHAKNLAIVWAPNLLRSKQ 185
M NL IV+ P L R +Q
Sbjct: 683 NRMTPHNLGIVFGPTLFRPEQ 703
>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
sapiens]
Length = 547
Score = 111 bits (277), Expect = 7e-24
Identities = 69/201 (34%), Positives = 103/201 (51%), Gaps = 20/201 (9%)
Query: 4 RPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGV 62
RP Q L++RG+L+++VFGC L G VP L+ C A +++ G+ VDGIYR+SG
Sbjct: 320 RPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGN 379
Query: 63 ASNIQRLRHEFDSEHVP------------------DLTKEPYVQDIHSVGSLCKLYFREL 104
+ +Q+LR D E DL + DIH V KL+ REL
Sbjct: 380 LAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEW-DDIHVVTGALKLFLREL 438
Query: 105 PNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSI 164
P PL+ L F A++ + E+ L +I ++I +P P++ TL +L+ HL + +
Sbjct: 439 PQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDK 498
Query: 165 TNMHAKNLAIVWAPNLLRSKQ 185
M NL IV+ P L R +Q
Sbjct: 499 NRMTPHNLGIVFGPTLFRPEQ 519
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 108 bits (269), Expect = 6e-23
Identities = 65/221 (29%), Positives = 112/221 (50%), Gaps = 11/221 (4%)
Query: 21 FGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFD--SEH 77
FG L EHL SG E+ +++C + G+ + G++R+ AS +++L+ D + H
Sbjct: 250 FGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSH 309
Query: 78 VPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVI 137
+ + +P H+V K Y RELP PL+T+ LYE+++ S +++L +
Sbjct: 310 LDEFYSDP-----HAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTC 364
Query: 138 QQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAF 197
Q+LPP ++ +L++ L+ LA + M N+AIV PNLL ++ + AA
Sbjct: 365 QKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAR--NEGTLAEMAAA 422
Query: 198 MEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKS 238
V + + V+E I+ H D F + + E L+ P S
Sbjct: 423 TSVHVVA-VIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSS 462
Score = 41.2 bits (95), Expect = 0.009
Identities = 82/331 (24%), Positives = 113/331 (34%), Gaps = 53/331 (16%)
Query: 683 PPPPPKNVARMLALALAESAQQASTQSLKRPGT--SQAGYTNYG----DIAVATTEDNLS 736
PP PP + + ++ Q + +S GT S AG G D + +D +S
Sbjct: 525 PPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVS 584
Query: 737 SSYSAVALDKAYF-----QTDRPAEQFHLQNNAPGNCDHPLPETTATG------DPTHSN 785
++ A + + Q A L P N P P T P
Sbjct: 585 AAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPG 644
Query: 786 TTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPT 845
G Q +G H LS P R S P H P G+ S P+
Sbjct: 645 NPPPGHPGGQSS-SGTSQHPPSLSPKPP-TRSPSPPTQ------HTGQPP---GQPSAPS 693
Query: 846 VSFLDQDQSPPRFYSG--------DQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDK-I 896
S PR YS + PP L H + P P LPS+ +
Sbjct: 694 ------QLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGL 747
Query: 897 YPPSGSPEENTSTATMTYMTTTPATAQMSTKEASWDVAE-QPTTADFAAATLQRTHRTNR 955
PS +P + T T +T P Q + A +A P TA A TL R R
Sbjct: 748 EQPSHTPPQ-----TPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRP----R 798
Query: 956 PLPPPPSQRSAEQPPVVGQVQAATNIGLNNS 986
P+P P ++ S PP V +A + L N+
Sbjct: 799 PVPKPRNRPSVPPPPQPPGVHSAGDSSLTNT 829
Score = 33.9 bits (76), Expect = 1.4
Identities = 57/262 (21%), Positives = 87/262 (33%), Gaps = 43/262 (16%)
Query: 761 QNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSV 820
Q +PG+ P P+ DP + G + Q+ NQP A S +
Sbjct: 567 QGPSPGDGSPPKPK-----DPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQ---- 617
Query: 821 PLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLG--ASVDKLHHP 878
P + +G S T+ + +P G+ PP + G +S HP
Sbjct: 618 -------------PHNAAGP-SPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHP 663
Query: 879 LEFADKSPT-PPNLPSDKIYPPSGSPEENTS-TATMTYMTT---------------TPAT 921
+ K PT P+ P+ P G P + +A Y ++ T AT
Sbjct: 664 PSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQAT 723
Query: 922 AQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNI 981
M TK S P Q +H + PP + +Q P + Q
Sbjct: 724 PLMHTKPNSQG-PPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGG 782
Query: 982 GLNNSHKVQGVVPVPERPPEPR 1003
+ G +P P P+PR
Sbjct: 783 NPETAQPHAGTLPRPRPVPKPR 804
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 108 bits (269), Expect = 6e-23
Identities = 65/221 (29%), Positives = 112/221 (50%), Gaps = 11/221 (4%)
Query: 21 FGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFD--SEH 77
FG L EHL SG E+ +++C + G+ + G++R+ AS +++L+ D + H
Sbjct: 250 FGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSH 309
Query: 78 VPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVI 137
+ + +P H+V K Y RELP PL+T+ LYE+++ S +++L +
Sbjct: 310 LDEFYSDP-----HAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTC 364
Query: 138 QQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAF 197
Q+LPP ++ +L++ L+ LA + M N+AIV PNLL ++ + AA
Sbjct: 365 QKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAR--NEGTLAEMAAA 422
Query: 198 MEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKS 238
V + + V+E I+ H D F + + E L+ P S
Sbjct: 423 TSVHVVA-VIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSS 462
Score = 38.5 bits (88), Expect = 0.058
Identities = 55/219 (25%), Positives = 80/219 (36%), Gaps = 30/219 (13%)
Query: 771 PLPETTATGDPTH-SNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDD 829
P P P H + SG H L+ P ++ + T P +
Sbjct: 560 PAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRS----PSPPTQHTGQPPGQPSAPS 615
Query: 830 HVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLHHPLEFADKSPTPP 889
+S P S ++S + PP QPP+ L H + P P
Sbjct: 616 QLSAPRRYSS-----SLSPIQAPNHPP-----PQPPT----QATPLMHTKPNSQGPPNPM 661
Query: 890 NLPSDK-IYPPSGSPEENTSTATMTYMTTTPATAQMSTKEASWDVAE-QPTTADFAAATL 947
LPS+ + PS +P + T T +T P Q + A +A P TA A TL
Sbjct: 662 ALPSEHGLEQPSHTPPQ-----TPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTL 716
Query: 948 QRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNS 986
R RP+P P ++ S PP V +A + L N+
Sbjct: 717 PRP----RPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNT 751
Score = 33.9 bits (76), Expect = 1.4
Identities = 61/293 (20%), Positives = 96/293 (32%), Gaps = 43/293 (14%)
Query: 730 TTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTES 789
TT + S ++ D + RPA ++ + P P+ DP +
Sbjct: 458 TTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESPPKPK-----DPVSAAVPAP 512
Query: 790 GEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFL 849
G + Q+ NQP A S + P + +G S T+
Sbjct: 513 GRNNSQIASGQNQPQAAAGSHQLSMGQ-----------------PHNAAGP-SPHTLRRA 554
Query: 850 DQDQSPPRFYSGDQPPSYLG--ASVDKLHHPLEFADKSPT-PPNLPSDKIYPPSGSPEEN 906
+ +P G+ PP + G +S HP + K PT P+ P+ P G P
Sbjct: 555 VKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAP 614
Query: 907 TS-TATMTYMTT---------------TPATAQMSTKEASWDVAEQPTTADFAAATLQRT 950
+ +A Y ++ T AT M TK S P Q +
Sbjct: 615 SQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQG-PPNPMALPSEHGLEQPS 673
Query: 951 HRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPERPPEPR 1003
H + PP + +Q P + Q + G +P P P+PR
Sbjct: 674 HTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPR 726
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 103 bits (258), Expect = 1e-21
Identities = 70/207 (33%), Positives = 107/207 (51%), Gaps = 6/207 (2%)
Query: 19 RVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFDSEH 77
RV+G L HL G E+ +++C + G+ + G++RL+ AS ++RL+ S+
Sbjct: 272 RVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASD- 330
Query: 78 VPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVI 137
+ E + D H+V K Y RELP PL+T+ LY+ + A S RL + +V
Sbjct: 331 --PHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVC 388
Query: 138 QQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAF 197
+LPP + L +LM+ L+ LA+ + M N+AIV PNLL + E AA
Sbjct: 389 SRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAAS 448
Query: 198 MEVRIQSV-VVEFILNHVDVLFSGRIS 223
+ IQ V VVE ++ D LF G I+
Sbjct: 449 VS-SIQVVGVVEALIQSADTLFPGDIN 474
Score = 36.6 bits (83), Expect = 0.22
Identities = 49/207 (23%), Positives = 76/207 (36%), Gaps = 31/207 (14%)
Query: 886 PTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAA 945
PTP P+ P+ +P + A + T +++ + AS V P + AA
Sbjct: 505 PTPATTPA-----PAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPP--ETAAP 557
Query: 946 TLQRTHRTNRP------LPPPPSQRSAEQPPV---------VGQVQAATNIGLNNSHKVQ 990
RT RP +PPP S PP G QA + +S +
Sbjct: 558 VEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAP 617
Query: 991 GV-VPVPERPPEP---RAMDDPASAFISDSG-AAAAQCPMATAVQPGLPEKVRDGARVPL 1045
V P+P PP+P ++ PAS + G A+ + ++ Q L +G
Sbjct: 618 TVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEA 677
Query: 1046 LHLRAESVPAHPCGFPAPLPPTRMMES 1072
+ VP P P P P + E+
Sbjct: 678 I----SGVPTPPAIPPQPRPRSLASET 700
Score = 35.0 bits (79), Expect = 0.64
Identities = 45/173 (26%), Positives = 61/173 (35%), Gaps = 25/173 (14%)
Query: 1078 IHSSSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKT-------VYSSFARP 1130
+ + +D +S S + + P P P P P AS T V A P
Sbjct: 486 LQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASP 545
Query: 1131 DVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEPPASMGLRYNTYVA 1190
VT P P+ RP P + QV G+RS PPA +
Sbjct: 546 KVTRSP--PETAAPVEDMARRTKRPAPARP---TMPPPQVSGSRSSPPAPP-------LP 593
Query: 1191 PGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPY-PTIRRVQSLHAPPS 1242
PG + G R+ + SS+R P +PP P R QS +P S
Sbjct: 594 PGSGSPGTPQALPRRL-----VGSSLRAPTVPPPLPPTPPQPARRQSRRSPAS 641
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 102 bits (255), Expect = 2e-21
Identities = 76/272 (27%), Positives = 138/272 (50%), Gaps = 16/272 (5%)
Query: 9 KLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQ 67
K +Q +++ FG L EHL SG E+ +++C + G+ + G++R++ AS ++
Sbjct: 241 KAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLK 300
Query: 68 RLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDE 127
+L+ D V D+ + Y D H++ K Y RELP PL+T++LY+++ A + +
Sbjct: 301 KLKAALDC-CVVDV--QEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQD 357
Query: 128 ERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIE 187
++L + + ++LP ++ + +L++ LS L++Y + M N+AIV PNLL +
Sbjct: 358 KKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQ--- 414
Query: 188 SACFSGTAAFMEVRIQSV-VVEFILNHVDVLFSGRI--SMAMQEGAASLSRPKSLLVSSP 244
A + T V +Q V ++E I+ H D F G I ++ G+ + S P
Sbjct: 415 -AEGNITEMMTTVSLQIVGIIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMP 473
Query: 245 STKLLTLEEAQARTQAQVNSP--IVTENKYIE 274
S ++ A R Q P + T+N +E
Sbjct: 474 SP---DMDPADRRQPEQARRPLSVATDNMMLE 502
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 101 bits (252), Expect = 6e-21
Identities = 87/333 (26%), Positives = 144/333 (43%), Gaps = 31/333 (9%)
Query: 39 VLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRH-----EFDSEHVPDLTKEPYVQDIHS 92
+++ C +E GI + G+YR+ GV S +Q+L + SE D+ E +I +
Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAE---WEIKT 448
Query: 93 VGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLM 152
+ S K Y R LP PL+ YQ F A E R+ +IH ++ +LP + + L+ LM
Sbjct: 449 ITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLM 508
Query: 153 RHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILN 212
HL+ +A+ M NL +V+ P LLR ++ AA M+++ Q++V+E ++
Sbjct: 509 NHLANVANNHKQNLMTVANLGVVFGPTLLRPQE------ETVAAIMDIKFQNIVIEILIE 562
Query: 213 HVDVLFSGRISMAMQEGAASLSRPKSLLVSSP--STKLLTLEEAQARTQAQVNSPIVTEN 270
+ + +F+ M + LSR KS P S + LTL T+ Q + +
Sbjct: 563 NHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSIINS 622
Query: 271 KYIEVGEGP-------AALQGKFHT------IIEFPLERKRPQNKMKKSPVG-SWRSFFN 316
V P ++LQ ++ +++ P N SP+ SW F
Sbjct: 623 SLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLPPNPSPTSPLSPSWPMFSA 682
Query: 317 LGKSSSVSKRKLQRNESEPSEMKAMALKGGRAE 349
S + KA AL +AE
Sbjct: 683 PSSPMPTSSTSSDSSPVSTPFRKAKALYACKAE 715
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 101 bits (252), Expect = 6e-21
Identities = 91/351 (25%), Positives = 157/351 (44%), Gaps = 39/351 (11%)
Query: 39 VLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRH-----EFDSEHVPDLTKEPYVQDIHS 92
+++ C +E GI + G+YR+ GV S +Q+L + SE D+ E +I +
Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAE---WEIKT 448
Query: 93 VGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLM 152
+ S K Y R LP PL+ YQ F A E R+ +IH ++ +LP + + L+ LM
Sbjct: 449 ITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLM 508
Query: 153 RHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILN 212
HL+ +A+ M NL +V+ P LLR ++ AA M+++ Q++V+E ++
Sbjct: 509 NHLANVANNHKQNLMTVANLGVVFGPTLLRPQE------ETVAAIMDIKFQNIVIEILIE 562
Query: 213 HVDVLFSGRISMAMQEGAASLSRPKSLLVSSP--STKLLTLEEAQARTQAQVNSPIVTEN 270
+ + +F+ M + LSR KS P S + LTL T+ Q + +
Sbjct: 563 NHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSIINS 622
Query: 271 KYIEVGEGP-------AALQGKFHT------IIEFPLERKRPQNKMKKSPVG-SWRSFFN 316
V P ++LQ ++ +++ P N SP+ SW F
Sbjct: 623 SLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLPPNPSPTSPLSPSWPMF-- 680
Query: 317 LGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAV 367
S+ S S+ S ++++A G ++ + + +SLHAV
Sbjct: 681 ---SAPSSPMPTSSTSSDSSPVRSVA---GFVWFSVAAVVLSLARSSLHAV 725
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 97.4 bits (241), Expect = 1e-19
Identities = 57/170 (33%), Positives = 94/170 (55%), Gaps = 2/170 (1%)
Query: 20 VFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFDSEHV 78
VFG + +VP +++ C IER G+ + GIYR+SGVA++IQ L+ FD +
Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNN- 1065
Query: 79 PDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQ 138
D++ D++++ KLYFRELP PL T + Y F++ ++ + + + +++
Sbjct: 1066 KDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLL 1125
Query: 139 QLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIES 188
LP + T FL+ HL +A+ ++ M NLA V+ P LLR + ES
Sbjct: 1126 SLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKES 1175
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 97.4 bits (241), Expect = 1e-19
Identities = 57/170 (33%), Positives = 94/170 (55%), Gaps = 2/170 (1%)
Query: 20 VFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFDSEHV 78
VFG + +VP +++ C IER G+ + GIYR+SGVA++IQ L+ FD +
Sbjct: 1051 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNN- 1109
Query: 79 PDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQ 138
D++ D++++ KLYFRELP PL T + Y F++ ++ + + + +++
Sbjct: 1110 KDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLL 1169
Query: 139 QLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIES 188
LP + T FL+ HL +A+ ++ M NLA V+ P LLR + ES
Sbjct: 1170 SLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKES 1219
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 96.7 bits (239), Expect = 2e-19
Identities = 62/168 (36%), Positives = 94/168 (55%), Gaps = 5/168 (2%)
Query: 16 LKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFD 74
L R FG +L L + VP V++ +IE +G+ +GIYR SG + I+ LR D
Sbjct: 2056 LSSRQFGVELSR-LTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLD 2114
Query: 75 SEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIH 134
++ + + Y +IH + S+ K + R+LPNPL+T++LYE+F A+ +E + ++
Sbjct: 2115 TD-AESVNLDDY--NIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVY 2171
Query: 135 DVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLR 182
VI QL H TLE L+ HL +A M A LAIV+AP +LR
Sbjct: 2172 SVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILR 2219
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 95.1 bits (235), Expect = 5e-19
Identities = 67/251 (26%), Positives = 122/251 (48%), Gaps = 36/251 (14%)
Query: 39 VLQSCTAFIERYGIVD-GIYRLSGVASNIQRLR---------HEFDSEHVPDLTKEPYVQ 88
+++ C + +E GI D G+YR+ GV+S +QRL +E D E+ D
Sbjct: 398 IIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADW------- 450
Query: 89 DIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTL 148
++ ++ S K Y R LP PL+TY+L+ F + + E R+ IH ++ +LP + L
Sbjct: 451 EVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEML 510
Query: 149 EFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVE 208
+ L++HL+ ++++ M NL +V+ P L+R ++ AA M+++ Q++VVE
Sbjct: 511 DILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQE------ETVAALMDLKFQNIVVE 564
Query: 209 FILNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQ-VNSPIV 267
++ + + +F E P L S P+ Q++ Q Q P+
Sbjct: 565 ILIENHEKIFRTPPDTTFPE-------PTCLSASPPNA-----PPRQSKRQGQRTKRPVA 612
Query: 268 TENKYIEVGEG 278
N +E+ +G
Sbjct: 613 VYNLCLELEDG 623
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 94.7 bits (234), Expect = 7e-19
Identities = 94/393 (23%), Positives = 161/393 (40%), Gaps = 34/393 (8%)
Query: 37 PQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGS 95
P +++ C FI + G+ + G++RL G A+ ++ L+ FD P D+H+V S
Sbjct: 58 PMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNT---DVHTVAS 114
Query: 96 LCKLYFRELPNPLLTYQLYEKFSDAVSAATDEER--LIKIHDVIQQLPPPHYRTLEFLMR 153
L KLY RELP P++ Y YE F + EE + ++ ++ LP +Y L+++ R
Sbjct: 115 LLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICR 174
Query: 154 HLSLLADYCSITNMHAKNLAIVWAPNLLRSK-QIESACFSGTAAFMEVRIQSVVVEFILN 212
L + Y + M +NLA V+ PN+LR K + GT V +Q ++ I
Sbjct: 175 FLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGT-----VVVQQLMSVMISK 229
Query: 213 HVDVLF--SGRISMAMQEGAASLSR-PKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTE 269
H D LF + Q+G ++ + K + K + Q + +
Sbjct: 230 H-DCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCSWDKSESPQ 288
Query: 270 NKYIEVGEGPAALQGK-----FHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVS 324
+ G P AL G +++ + + R P K G SS +
Sbjct: 289 RSSMNNG-SPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSN 347
Query: 325 KRKLQRNESEPS-EMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSS 383
L++ ++ P+ ++A + GT S ++ T + L P R+ S
Sbjct: 348 AEGLEKTQTTPNGSLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMS 407
Query: 384 ----------DALSASFNGEM-LGNRCNSYDNL 405
D GE+ NR ++YDN+
Sbjct: 408 WLPNGYVTLRDNKQKEQAGELGQHNRLSTYDNV 440
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,528,274
Number of Sequences: 37866
Number of extensions: 4289242
Number of successful extensions: 19257
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 516
Number of HSP's that attempted gapping in prelim test: 15722
Number of HSP's gapped (non-prelim): 3540
length of query: 1738
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1622
effective length of database: 13,855,062
effective search space: 22472910564
effective search space used: 22472910564
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.