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Search of human proteins with 29336063
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29336063 plexin B3 isoform 1 [Homo sapiens]
(1909 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29336063 plexin B3 isoform 1 [Homo sapiens] 3892 0.0
gi|253795481 plexin B3 isoform 2 [Homo sapiens] 3859 0.0
gi|194272180 plexin B1 [Homo sapiens] 1264 0.0
gi|40254442 plexin B1 [Homo sapiens] 1264 0.0
gi|149363636 plexin B2 [Homo sapiens] 1210 0.0
gi|113722116 plexin A2 [Homo sapiens] 963 0.0
gi|157694524 plexin D1 [Homo sapiens] 962 0.0
gi|49355818 plexin A1 [Homo sapiens] 955 0.0
gi|157738645 plexin A4 isoform 1 [Homo sapiens] 927 0.0
gi|59710104 plexin A3 [Homo sapiens] 913 0.0
gi|5032223 plexin C1 [Homo sapiens] 384 e-106
gi|157738643 plexin A4 isoform 2 [Homo sapiens] 120 1e-26
gi|157738647 plexin A4 isoform 3 [Homo sapiens] 112 3e-24
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens] 100 1e-20
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s... 95 7e-19
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens] 91 1e-17
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 62 5e-09
gi|157388902 semaphorin 4C [Homo sapiens] 61 9e-09
gi|21361914 semaphorin B [Homo sapiens] 58 1e-07
gi|147904700 semaphorin 5A [Homo sapiens] 55 9e-07
gi|39777610 semaphorin 4B precursor [Homo sapiens] 54 1e-06
gi|39777608 semaphorin 4B precursor [Homo sapiens] 54 1e-06
gi|19718780 semaphorin 6B precursor [Homo sapiens] 52 4e-06
gi|28872814 semaphorin 4G [Homo sapiens] 52 7e-06
gi|126116589 fibrocystin L [Homo sapiens] 51 9e-06
gi|11991660 sema domain, transmembrane domain (TM), and cytoplas... 49 6e-05
gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 47 1e-04
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 47 1e-04
gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] 47 1e-04
gi|19923279 semaphorin W [Homo sapiens] 46 4e-04
>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
Length = 1909
Score = 3892 bits (10094), Expect = 0.0
Identities = 1909/1909 (100%), Positives = 1909/1909 (100%)
Query: 1 MCHAAQETPLLHHFMAPVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAPNTTLNHLALA 60
MCHAAQETPLLHHFMAPVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAPNTTLNHLALA
Sbjct: 1 MCHAAQETPLLHHFMAPVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAPNTTLNHLALA 60
Query: 61 PGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLL 120
PGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLL
Sbjct: 61 PGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLL 120
Query: 121 LVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPL 180
LVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPL
Sbjct: 121 LVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPL 180
Query: 181 PGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDFSDYNNSYVGAFAD 240
PGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDFSDYNNSYVGAFAD
Sbjct: 181 PGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDFSDYNNSYVGAFAD 240
Query: 241 ARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLIQAAFLAPGTLL 300
ARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLIQAAFLAPGTLL
Sbjct: 241 ARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLIQAAFLAPGTLL 300
Query: 301 GVFAAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTL 360
GVFAAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTL
Sbjct: 301 GVFAAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTL 360
Query: 361 PLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQL 420
PLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQL
Sbjct: 361 PLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQL 420
Query: 421 YKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDC 480
YKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDC
Sbjct: 421 YKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDC 480
Query: 481 ASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQE 540
ASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQE
Sbjct: 481 ASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQE 540
Query: 541 QGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTV 600
QGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTV
Sbjct: 541 QGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTV 600
Query: 601 PLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPE 660
PLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPE
Sbjct: 601 PLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPE 660
Query: 661 GERTIYSAQEVDIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHC 720
GERTIYSAQEVDIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHC
Sbjct: 661 GERTIYSAQEVDIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHC 720
Query: 721 WLELPGELRGLPATLEETAGDSGLIHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHA 780
WLELPGELRGLPATLEETAGDSGLIHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHA
Sbjct: 721 WLELPGELRGLPATLEETAGDSGLIHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHA 780
Query: 781 LYVILYDCAMGHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAV 840
LYVILYDCAMGHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAV
Sbjct: 781 LYVILYDCAMGHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAV 840
Query: 841 EPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPN 900
EPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPN
Sbjct: 841 EPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPN 900
Query: 901 GTTGPVRVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSA 960
GTTGPVRVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSA
Sbjct: 901 GTTGPVRVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSA 960
Query: 961 FVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAA 1020
FVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAA
Sbjct: 961 FVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAA 1020
Query: 1021 EPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAAD 1080
EPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAAD
Sbjct: 1021 EPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAAD 1080
Query: 1081 PQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAVPDRAHPQRVFFTLDNVQVDFASASGGQ 1140
PQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAVPDRAHPQRVFFTLDNVQVDFASASGGQ
Sbjct: 1081 PQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAVPDRAHPQRVFFTLDNVQVDFASASGGQ 1140
Query: 1141 GFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTL 1200
GFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTL
Sbjct: 1141 GFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTL 1200
Query: 1201 TRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGM 1260
TRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGM
Sbjct: 1201 TRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGM 1260
Query: 1261 GAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLS 1320
GAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLS
Sbjct: 1261 GAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLS 1320
Query: 1321 SDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSK 1380
SDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSK
Sbjct: 1321 SDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSK 1380
Query: 1381 LFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPK 1440
LFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPK
Sbjct: 1381 LFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPK 1440
Query: 1441 LMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRT 1500
LMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRT
Sbjct: 1441 LMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRT 1500
Query: 1501 LNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVY 1560
LNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVY
Sbjct: 1501 LNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVY 1560
Query: 1561 KGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGL 1620
KGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGL
Sbjct: 1561 KGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGL 1620
Query: 1621 VPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLRER 1680
VPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLRER
Sbjct: 1621 VPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLRER 1680
Query: 1681 EPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHG 1740
EPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHG
Sbjct: 1681 EPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHG 1740
Query: 1741 IEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHK 1800
IEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHK
Sbjct: 1741 IEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHK 1800
Query: 1801 VGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLE 1860
VGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLE
Sbjct: 1801 VGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLE 1860
Query: 1861 ALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1909
ALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL
Sbjct: 1861 ALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1909
>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
Length = 1932
Score = 3859 bits (10007), Expect = 0.0
Identities = 1894/1894 (100%), Positives = 1894/1894 (100%)
Query: 16 APVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLF 75
APVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLF
Sbjct: 39 APVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLF 98
Query: 76 QLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQV 135
QLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQV
Sbjct: 99 QLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQV 158
Query: 136 RQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGK 195
RQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGK
Sbjct: 159 RQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGK 218
Query: 196 LSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARA 255
LSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARA
Sbjct: 219 LSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARA 278
Query: 256 QAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLIQAAFLAPGTLLGVFAAGPRGTQAALC 315
QAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLIQAAFLAPGTLLGVFAAGPRGTQAALC
Sbjct: 279 QAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLIQAAFLAPGTLLGVFAAGPRGTQAALC 338
Query: 316 AFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHT 375
AFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHT
Sbjct: 339 AFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHT 398
Query: 376 PSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHS 435
PSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHS
Sbjct: 399 PSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHS 458
Query: 436 QQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCV 495
QQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCV
Sbjct: 459 QQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCV 518
Query: 496 LQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILD 555
LQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILD
Sbjct: 519 LQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILD 578
Query: 556 ADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATN 615
ADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATN
Sbjct: 579 ADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATN 638
Query: 616 FSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQV 675
FSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQV
Sbjct: 639 FSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQV 698
Query: 676 RGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATL 735
RGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATL
Sbjct: 699 RGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATL 758
Query: 736 EETAGDSGLIHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDC 795
EETAGDSGLIHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDC
Sbjct: 759 EETAGDSGLIHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDC 818
Query: 796 SHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTI 855
SHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTI
Sbjct: 819 SHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTI 878
Query: 856 LGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPP 915
LGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPP
Sbjct: 879 LGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPP 938
Query: 916 GISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCP 975
GISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCP
Sbjct: 939 GISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCP 998
Query: 976 EAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRV 1035
EAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRV
Sbjct: 999 EAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRV 1058
Query: 1036 RGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCS 1095
RGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCS
Sbjct: 1059 RGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCS 1118
Query: 1096 TVCSVNSSSLLLCRSPAVPDRAHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSR 1155
TVCSVNSSSLLLCRSPAVPDRAHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSR
Sbjct: 1119 TVCSVNSSSLLLCRSPAVPDRAHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSR 1178
Query: 1156 EGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQ 1215
EGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQ
Sbjct: 1179 EGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQ 1238
Query: 1216 PANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLM 1275
PANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLM
Sbjct: 1239 PANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLM 1298
Query: 1276 YRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRT 1335
YRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRT
Sbjct: 1299 YRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRT 1358
Query: 1336 YAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPS 1395
YAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPS
Sbjct: 1359 YAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPS 1418
Query: 1396 FSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLT 1455
FSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLT
Sbjct: 1419 FSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLT 1478
Query: 1456 NWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQP 1515
NWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQP
Sbjct: 1479 NWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQP 1538
Query: 1516 LTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALD 1575
LTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALD
Sbjct: 1539 LTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALD 1598
Query: 1576 LEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLA 1635
LEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLA
Sbjct: 1599 LEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLA 1658
Query: 1636 QRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTR 1695
QRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTR
Sbjct: 1659 QRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTR 1718
Query: 1696 LLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSL 1755
LLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSL
Sbjct: 1719 LLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSL 1778
Query: 1756 LLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYARE 1815
LLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYARE
Sbjct: 1779 LLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYARE 1838
Query: 1816 IPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQ 1875
IPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQ
Sbjct: 1839 IPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQ 1898
Query: 1876 IISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1909
IISALEEDPVGQKLQLACRLQQVAALVENKVTDL
Sbjct: 1899 IISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1932
>gi|194272180 plexin B1 [Homo sapiens]
Length = 2135
Score = 1264 bits (3272), Expect = 0.0
Identities = 690/1257 (54%), Positives = 842/1257 (66%), Gaps = 40/1257 (3%)
Query: 670 EVDIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELR 729
E++ G +CP VE + G L+PV E + L RNL F+ P C +EL G
Sbjct: 902 ELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEV 961
Query: 730 GLPATLE-ETAGDSGL-IHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYD 787
+ A +E E D+ + CQ HQ Q EL V +++ + R+D+ L+V+LYD
Sbjct: 962 VVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYD 1021
Query: 788 CAMGHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPG-AVELLCPAPSIDAVEPLTGP 846
C++GH DCS CQ A GC+WC +P C C AV CPAP I +VEPLTGP
Sbjct: 1022 CSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGP 1081
Query: 847 PEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPV 906
+GG +TI GSNLG+ DV V+VA PC + Y S+ +VC+T + G
Sbjct: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141
Query: 907 RVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGG--NTSAFVGG 964
V + + G+S F YQDP + S+ P GP+AGGT+LT+ G L TG + VG
Sbjct: 1142 AVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD 1201
Query: 965 QPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSA 1024
QPC +L E + C T P+ P V V FG +R L F+YT +P + +A P+
Sbjct: 1202 QPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTK 1261
Query: 1025 SFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQAC 1084
SF GGR I VRG LDVVQ P + V V + QP RR P+
Sbjct: 1262 SFLSGGREICVRGQNLDVVQTPRIRV------TVVSRMLQPSQGLGRRR----RVVPETA 1311
Query: 1085 IQLGGGLL--QCSTVCSVNSSSLLLCRSPAVPDRAHPQ--RVFFTLDNVQVDFASASGGQ 1140
LG Q C VNSS L+ CR+PA+P RV F LDN+ DFA+ +
Sbjct: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTP 1371
Query: 1141 GFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTL 1200
F Y+ +P L PL+ E P P+R KPG V VEGE L+L +SKEEV IG G C+VKTL
Sbjct: 1372 -FSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTL 1430
Query: 1201 TRTHLYCEPPAHAPQPANGS------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1254
TR HLYCEPP P P + + LP+F VQMGN++ +LG VQY+ E P AFPV A
Sbjct: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESP-GAFPVAA 1489
Query: 1255 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1314
Q G+G+G ++L V+++ LMYR KSKQALRDY+KV +QLE+LE+ V D+C+KEFTDLMT
Sbjct: 1490 QVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMT 1549
Query: 1315 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1374
EMTDL+SDL GSGIPFLDY+ YAER FFPGH PL P + TV QGL QLS
Sbjct: 1550 EMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVP--ESRRPTVEQGLGQLS 1607
Query: 1375 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1434
NLLNSKLFL IHTLE Q +FS RDR +VASLL++ALHGKLEY TDI+RTLL DL A Y
Sbjct: 1608 NLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQY 1667
Query: 1435 VHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVT 1494
V +NPKLMLRRTET+VEKLLTNW+SICLY F+R+ GEPLYMLFR I++QVDKGPVD+VT
Sbjct: 1668 VAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVT 1727
Query: 1495 GKAKRTLNDSRLLREDVEFQPLTLMVL--VGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1552
GKAK TLND+RLLREDVE++PLTL L VGPGAG A G VP +VLD DTI+Q K
Sbjct: 1728 GKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQG------VPVKVLDCDTISQAK 1781
Query: 1553 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1612
EK+LDQ+YKG P +QRP LD+EWRSG+AGHL LSDED+TS Q W+RLNTLQHYKV
Sbjct: 1782 EKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKV 1841
Query: 1613 PDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKV 1672
PDGATV LVP L + + + P GE P LED +EGG+ WHLVK ++EPE +
Sbjct: 1842 PDGATVALVPCLTKH--VLRENQDYVP-GERTPMLEDVDEGGIRPWHLVKPSDEPEPPRP 1898
Query: 1673 RCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLL 1732
R SLR E RAKAIPEIYLTRLLSMKGTLQKFVDD FQ ILS +RP+P+AVKY FDLL
Sbjct: 1899 RRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLL 1958
Query: 1733 DELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFID 1792
DE A++HGI D T+HIWKTNSL LRFW+N +KNPQ +FDV+ SDN+DA+L VIAQTF+D
Sbjct: 1959 DEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMD 2018
Query: 1793 SCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNY 1852
+CT ++HK+GRDSP+NKLLYAR+IPRYK+MVERYYADIRQ+ PAS QEMNS LAELS NY
Sbjct: 2019 ACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNY 2078
Query: 1853 TSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1909
+ AL ELY +I++YYDQII+ALEED QK+QL RLQQ+AA VENKVTDL
Sbjct: 2079 SGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
Score = 560 bits (1442), Expect = e-159
Identities = 326/717 (45%), Positives = 417/717 (58%), Gaps = 51/717 (7%)
Query: 23 PPFGLCLLLLL-----LSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQL 77
P G LL L L+ PLP T F+ T L HLA P GTLY+GA N LFQL
Sbjct: 2 PALGPALLQALWAGWVLTLQPLPPTA---FTPNGTYLQHLARDPTSGTLYLGATNFLFQL 58
Query: 78 SPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQVRQ 137
SP LQLEA TGPV+DS DC+P P ECPQAQ T+N NQLLLVS A LV CG V Q
Sbjct: 59 SPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
Query: 138 GVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVP-LPGRDLLLVARGLAGK- 195
GVCE RRLG + ++L + E PGD Q+VAAN P V+TVGLV L G LL V RG +
Sbjct: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
Query: 196 LSAGVPPLAIRQLAGSQP---FSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRG 252
+ G+PP+ R L P FS E +L VG S+Y++ +V AFA SAYF+F RR
Sbjct: 177 VGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRD 236
Query: 253 ARAQAE-YRSYVARVCLGDTNLYSYVEVPLACQG--QGLIQAAFLAPG-------TLLGV 302
+AQ+ +R+YV+RVCL D + YSYVE+PLAC+G GLIQAA +A L
Sbjct: 237 LQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAA 296
Query: 303 F--------------AAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEAT 348
F AAG G +ALCAFP+ E+ + R CYT GR G E A
Sbjct: 297 FSSAAPPTVGRPPSAAAGASGA-SALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
Query: 349 VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKL-GQPVSAVAALQADG 407
+EY V S C LP+D+ ++YPCG +HTPSP+A R PLE P+L+ G ++AVA DG
Sbjct: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
Query: 408 HMIAFLGDTQGQLYKVFLH-GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQV 466
H IAFLGD+QGQL++V+L GS G Y +Q + GSA+S DL D + HLYV+T +
Sbjct: 416 HTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI-QQGSAVSRDLTFDGTFEHLYVMTQSTL 474
Query: 467 DRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCL 526
++PVA+C Q DCASCL +DP CGWCVL GRC+R+ +C R QWLWS++ + CL
Sbjct: 475 LKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCL 534
Query: 527 HIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQD 586
+ ++ P + R+E +V LSVP LP L E + C FG++ S A + G V C +P
Sbjct: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
Query: 587 QVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWC 646
+ P+ P G D+V+V + L F V +A T+ SFYDC AV L +A C+ACV S W C+WC
Sbjct: 595 EAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWC 654
Query: 647 PQSSHCVYGEHCPEGERTIYSAQEV---DIQVRG-----PGACPQVEGLAGPHLVPV 695
C + C G + D RG P P+ P +PV
Sbjct: 655 VWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPV 711
>gi|40254442 plexin B1 [Homo sapiens]
Length = 2135
Score = 1264 bits (3272), Expect = 0.0
Identities = 690/1257 (54%), Positives = 842/1257 (66%), Gaps = 40/1257 (3%)
Query: 670 EVDIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELR 729
E++ G +CP VE + G L+PV E + L RNL F+ P C +EL G
Sbjct: 902 ELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEV 961
Query: 730 GLPATLE-ETAGDSGL-IHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYD 787
+ A +E E D+ + CQ HQ Q EL V +++ + R+D+ L+V+LYD
Sbjct: 962 VVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYD 1021
Query: 788 CAMGHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPG-AVELLCPAPSIDAVEPLTGP 846
C++GH DCS CQ A GC+WC +P C C AV CPAP I +VEPLTGP
Sbjct: 1022 CSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGP 1081
Query: 847 PEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPV 906
+GG +TI GSNLG+ DV V+VA PC + Y S+ +VC+T + G
Sbjct: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141
Query: 907 RVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGG--NTSAFVGG 964
V + + G+S F YQDP + S+ P GP+AGGT+LT+ G L TG + VG
Sbjct: 1142 AVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD 1201
Query: 965 QPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSA 1024
QPC +L E + C T P+ P V V FG +R L F+YT +P + +A P+
Sbjct: 1202 QPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTK 1261
Query: 1025 SFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQAC 1084
SF GGR I VRG LDVVQ P + V V + QP RR P+
Sbjct: 1262 SFLSGGREICVRGQNLDVVQTPRIRV------TVVSRMLQPSQGLGRRR----RVVPETA 1311
Query: 1085 IQLGGGLL--QCSTVCSVNSSSLLLCRSPAVPDRAHPQ--RVFFTLDNVQVDFASASGGQ 1140
LG Q C VNSS L+ CR+PA+P RV F LDN+ DFA+ +
Sbjct: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTP 1371
Query: 1141 GFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTL 1200
F Y+ +P L PL+ E P P+R KPG V VEGE L+L +SKEEV IG G C+VKTL
Sbjct: 1372 -FSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTL 1430
Query: 1201 TRTHLYCEPPAHAPQPANGS------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1254
TR HLYCEPP P P + + LP+F VQMGN++ +LG VQY+ E P AFPV A
Sbjct: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESP-GAFPVAA 1489
Query: 1255 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1314
Q G+G+G ++L V+++ LMYR KSKQALRDY+KV +QLE+LE+ V D+C+KEFTDLMT
Sbjct: 1490 QVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMT 1549
Query: 1315 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1374
EMTDL+SDL GSGIPFLDY+ YAER FFPGH PL P + TV QGL QLS
Sbjct: 1550 EMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVP--ESRRPTVEQGLGQLS 1607
Query: 1375 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1434
NLLNSKLFL IHTLE Q +FS RDR +VASLL++ALHGKLEY TDI+RTLL DL A Y
Sbjct: 1608 NLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQY 1667
Query: 1435 VHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVT 1494
V +NPKLMLRRTET+VEKLLTNW+SICLY F+R+ GEPLYMLFR I++QVDKGPVD+VT
Sbjct: 1668 VAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVT 1727
Query: 1495 GKAKRTLNDSRLLREDVEFQPLTLMVL--VGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1552
GKAK TLND+RLLREDVE++PLTL L VGPGAG A G VP +VLD DTI+Q K
Sbjct: 1728 GKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQG------VPVKVLDCDTISQAK 1781
Query: 1553 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1612
EK+LDQ+YKG P +QRP LD+EWRSG+AGHL LSDED+TS Q W+RLNTLQHYKV
Sbjct: 1782 EKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKV 1841
Query: 1613 PDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKV 1672
PDGATV LVP L + + + P GE P LED +EGG+ WHLVK ++EPE +
Sbjct: 1842 PDGATVALVPCLTKH--VLRENQDYVP-GERTPMLEDVDEGGIRPWHLVKPSDEPEPPRP 1898
Query: 1673 RCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLL 1732
R SLR E RAKAIPEIYLTRLLSMKGTLQKFVDD FQ ILS +RP+P+AVKY FDLL
Sbjct: 1899 RRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLL 1958
Query: 1733 DELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFID 1792
DE A++HGI D T+HIWKTNSL LRFW+N +KNPQ +FDV+ SDN+DA+L VIAQTF+D
Sbjct: 1959 DEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMD 2018
Query: 1793 SCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNY 1852
+CT ++HK+GRDSP+NKLLYAR+IPRYK+MVERYYADIRQ+ PAS QEMNS LAELS NY
Sbjct: 2019 ACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNY 2078
Query: 1853 TSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1909
+ AL ELY +I++YYDQII+ALEED QK+QL RLQQ+AA VENKVTDL
Sbjct: 2079 SGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
Score = 560 bits (1442), Expect = e-159
Identities = 326/717 (45%), Positives = 417/717 (58%), Gaps = 51/717 (7%)
Query: 23 PPFGLCLLLLL-----LSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQL 77
P G LL L L+ PLP T F+ T L HLA P GTLY+GA N LFQL
Sbjct: 2 PALGPALLQALWAGWVLTLQPLPPTA---FTPNGTYLQHLARDPTSGTLYLGATNFLFQL 58
Query: 78 SPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQVRQ 137
SP LQLEA TGPV+DS DC+P P ECPQAQ T+N NQLLLVS A LV CG V Q
Sbjct: 59 SPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
Query: 138 GVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVP-LPGRDLLLVARGLAGK- 195
GVCE RRLG + ++L + E PGD Q+VAAN P V+TVGLV L G LL V RG +
Sbjct: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
Query: 196 LSAGVPPLAIRQLAGSQP---FSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRG 252
+ G+PP+ R L P FS E +L VG S+Y++ +V AFA SAYF+F RR
Sbjct: 177 VGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRD 236
Query: 253 ARAQAE-YRSYVARVCLGDTNLYSYVEVPLACQG--QGLIQAAFLAPG-------TLLGV 302
+AQ+ +R+YV+RVCL D + YSYVE+PLAC+G GLIQAA +A L
Sbjct: 237 LQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAA 296
Query: 303 F--------------AAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEAT 348
F AAG G +ALCAFP+ E+ + R CYT GR G E A
Sbjct: 297 FSSAAPPTVGRPPSAAAGASGA-SALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
Query: 349 VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKL-GQPVSAVAALQADG 407
+EY V S C LP+D+ ++YPCG +HTPSP+A R PLE P+L+ G ++AVA DG
Sbjct: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
Query: 408 HMIAFLGDTQGQLYKVFLH-GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQV 466
H IAFLGD+QGQL++V+L GS G Y +Q + GSA+S DL D + HLYV+T +
Sbjct: 416 HTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI-QQGSAVSRDLTFDGTFEHLYVMTQSTL 474
Query: 467 DRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCL 526
++PVA+C Q DCASCL +DP CGWCVL GRC+R+ +C R QWLWS++ + CL
Sbjct: 475 LKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCL 534
Query: 527 HIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQD 586
+ ++ P + R+E +V LSVP LP L E + C FG++ S A + G V C +P
Sbjct: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
Query: 587 QVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWC 646
+ P+ P G D+V+V + L F V +A T+ SFYDC AV L +A C+ACV S W C+WC
Sbjct: 595 EAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWC 654
Query: 647 PQSSHCVYGEHCPEGERTIYSAQEV---DIQVRG-----PGACPQVEGLAGPHLVPV 695
C + C G + D RG P P+ P +PV
Sbjct: 655 VWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPV 711
>gi|149363636 plexin B2 [Homo sapiens]
Length = 1838
Score = 1210 bits (3131), Expect = 0.0
Identities = 764/1901 (40%), Positives = 1049/1901 (55%), Gaps = 141/1901 (7%)
Query: 54 LNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLT 113
LNHLA+ G +Y+GAVN L+QL +LQLE TGP +D+ C P + ++C +A++T
Sbjct: 34 LNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEAEMT 93
Query: 114 DNANQLLLVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVAT 173
DN NQLLL+ + LV CG + +G+C R L +++ L+ + G+ FVA+N GVAT
Sbjct: 94 DNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEGVAT 153
Query: 174 VGLVVPL-PGRDLLLVARGLAGKLSAG--VPPLAIRQLAGSQPFSS-EGLGRLVVGDFSD 229
VGLV PG D +L G G V + + + F + G S
Sbjct: 154 VGLVSSTGPGGDRVLFVGKGNGPHDNGIIVSTRLLDRTDSREAFEAYTDHATYKAGYLST 213
Query: 230 YNNSYVGAFADARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLI 289
+V AF D +FVF ++ + A R+ +AR+C D N YSY+E+ L C+ +
Sbjct: 214 NTQQFVAAFEDGPYVFFVFNQQD-KHPARNRTLLARMCREDPNYYSYLEMDLQCRDPDIH 272
Query: 290 QAAF--------LAPGT---LLGVFAAGPR---GTQAALCAFPMVELGASMEQARRLCYT 335
AAF APG+ L VF+ R G A LC FP+ ++ A ME R CYT
Sbjct: 273 AAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPGAGLCLFPLDKVHAKMEANRNACYT 332
Query: 336 AGGRGPSGAEEAT----VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLL 391
G EA + +C S +S+PCG EH P P+ R L +L
Sbjct: 333 -------GTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVL 385
Query: 392 KLGQ-PVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLL 450
+ G ++AV + H +AFLG + G++ KV+L + + + DL+
Sbjct: 386 QRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLV 445
Query: 451 LDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAG 510
L LY +T +V R+PV C +P C C +QDP CGWCV++GRCTRK +C RA
Sbjct: 446 LSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAE 505
Query: 511 QLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSL 570
+ + WLWS + C+ + S P + R+ QG+V L+V LP L ++ C FG+
Sbjct: 506 EASHWLWSRSKS--CVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEEDELLCLFGESPPH 563
Query: 571 -AHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATNFS--FYDCSAVQAL 627
A VEG V C +P +P+ PPG DHV V + L+ + T++ FYDC +L
Sbjct: 564 PARVEGEAVICNSP--SSIPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSL 621
Query: 628 EAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGL 687
E PC +CV + W C W + C E P E I A D +CPQ G
Sbjct: 622 EENLPCISCVSNRWTCQWDLRYHEC--REASPNPEDGIVRAHMED-------SCPQFLG- 671
Query: 688 AGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHC 747
P ++P+ E+ + + +NL +G +S H +L + P T++E+ +
Sbjct: 672 PSPLVIPMNHETDVNFQGKNLDTVKG--SSLHVGSDLLKFME--PVTMQESGTFAFRTPK 727
Query: 748 QAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGC 807
+H + LP+ +YV + + +D+ L+V LY+C+ G DCS C+AAN C
Sbjct: 728 LSHD-----ANETLPLHLYV-KSYGKNIDSK--LHVTLYNCSFGRSDCSLCRAANPDYRC 779
Query: 808 LWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADV 867
WC GQ C Y LC + CP P I ++P TGP GG+ +TILGSNLG D+
Sbjct: 780 AWCG-GQSRCVYEALCNTTSE---CPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDI 835
Query: 868 QYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQ----PPGISSQHFT 923
Q +SVA R C+ +P Y S RIVCV A TG V V + + PP + FT
Sbjct: 836 Q-RISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQ---FT 891
Query: 924 YQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFV--GGQPCPILEPVCPEAIVCR 981
+Q P LS+ P+ GPQAGGT LTI G HL TG V G PC + + + C
Sbjct: 892 FQQPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTK--FGAQLQCV 949
Query: 982 TRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLD 1041
T PQA G+ + V +G + F Y NP L A EP SF GGR I V G G
Sbjct: 950 TGPQATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFS 1009
Query: 1042 VVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVN 1101
++QR + V E Q QP R A + P + T +
Sbjct: 1010 LIQRFAMVVIAEP----------LQSWQPPRE--AESLQPMTVV---------GTDYVFH 1048
Query: 1102 SSSLLLCRSPAVPDR--AHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPA 1159
+ + ++ SPAVP+ A+ V +D + + +G F Y P+P E
Sbjct: 1049 NDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGA--FEYVPDPTF-----ENFT 1101
Query: 1160 RPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANG 1219
+ + ++ G LN ++ +E +G C +KTLT T LYCEPP P P
Sbjct: 1102 GGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRR 1161
Query: 1220 S------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLT 1273
LP+F+V+ G+ + LG V+Y+ +S P+ + + V++ AV +
Sbjct: 1162 QKRDTTHNLPEFIVKFGSREWVLGRVEYDTR--VSDVPLSLILPLVIVPMVVVIAVSVYC 1219
Query: 1274 LMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDY 1333
Y KS+QA R+Y+K+ QLE LE V D+C+KEFTDLM EM D ++D+ +GIP LDY
Sbjct: 1220 --YWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDY 1277
Query: 1334 RTYAERAFF----PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHT 1389
+TY +R FF G + K + P + V Q L Q SNLLNSK FL+ IHT
Sbjct: 1278 KTYTDRVFFLPSKDGDKDVMITGKLDIP--EPRRPVVEQALYQFSNLLNSKSFLINFIHT 1335
Query: 1390 LEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYV-HRNPKLMLRRTET 1448
LE Q FS R + + ASLL++ALHGKLEY TDIM TL +L YV +NPKLMLRR+ET
Sbjct: 1336 LENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSET 1395
Query: 1449 MVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLR 1508
+VE++L+NW+SICLY +L++ AGEPLY LF+AI++QV+KGPVDAV KAK TLND+ LL
Sbjct: 1396 VVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLG 1455
Query: 1509 EDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQR 1568
+DVE+ PLT+ V+V + +P +VL+ DTI+QVKEK++DQVY+G P S
Sbjct: 1456 DDVEYAPLTVSVIVQ--------DEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCW 1507
Query: 1569 PSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGS 1628
P ++ LEWR G + LSD DLTS + WKR+NTL HY V DGAT+ L G
Sbjct: 1508 PRPDSVVLEWRPGSTAQI-LSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSKV---GV 1563
Query: 1629 TISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAI 1688
+ +Q+ GE LE+ +WHLV+ T+E + K + S++E+E R KAI
Sbjct: 1564 SQQPEDSQQDLPGERHALLEEENR----VWHLVRPTDEVDEGKSKRGSVKEKE--RTKAI 1617
Query: 1689 PEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHGIEDPGTLH 1748
EIYLTRLLS+KGTLQ+FVD+ FQ++L+ +P AVKY FD LDE AEKH I+D T+H
Sbjct: 1618 TEIYLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIH 1677
Query: 1749 IWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVN 1808
IWKTNSL LRFWVN LKNP IFDV V + VDA L+VIAQTF+D+CT +EHK+ RDSP N
Sbjct: 1678 IWKTNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSN 1737
Query: 1809 KLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNH 1868
KLLYA+EI YK+MVE YY IRQ S Q+MN+ LAE+S +T + + L AL +LY +
Sbjct: 1738 KLLYAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQY 1797
Query: 1869 IHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1909
+YYD+II+ALEEDP QK+QLA RLQQ+AA +ENKVTDL
Sbjct: 1798 TQKYYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1838
>gi|113722116 plexin A2 [Homo sapiens]
Length = 1894
Score = 963 bits (2490), Expect = 0.0
Identities = 663/1980 (33%), Positives = 990/1980 (50%), Gaps = 222/1980 (11%)
Query: 27 LCLLLLLLSPPPLPLTGAHRFSAPNT--TLNHLALAPGRGTLYVGAVNRLFQLSPELQLE 84
L ++ +LL+PP + F + N T NHL + G G +YVGA+NR+++L+ L ++
Sbjct: 21 LSVVWVLLAPPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVYVGAINRVYKLTGNLTIQ 80
Query: 85 AVAVTGPVIDSPDCVPFRDPAECPQA-QLTDNANQLLLVSSRAQELVACGQVRQGVCETR 143
TGP D+ C P C + LT+N N+LL++ L+ACG + QGVC+
Sbjct: 81 VAHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSENRLLACGSLYQGVCKLL 140
Query: 144 RLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRD-LLLVARGLAGKLSAGVPP 202
RL D+ +L + + + N G G++V G D L + + GK P
Sbjct: 141 RLDDLF-ILVEPSHKKEHYLSSVNKTGTM-YGVIVRSEGEDGKLFIGTAVDGKQDY-FPT 197
Query: 203 LAIRQLAGSQPFSSEGLGRLVVGDF---------------SDYNNSYVGAFADARSAYFV 247
L+ R+L P SS L + DF S ++ Y+ FA YF+
Sbjct: 198 LSSRKLP-RDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFL 256
Query: 248 FRRR--------GARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA 295
+ + Y S + R+C D +SYV +P C G L+QAA+LA
Sbjct: 257 TVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYLA 316
Query: 296 -PG--------------TLLGVFAAGPRG-----TQAALCAFPMVELGASMEQARRLCYT 335
PG L +F+ G + +ALCAFP+ + +++ + CY
Sbjct: 317 KPGDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIKERLQSCYQ 376
Query: 336 AGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQ 395
G E G +C P+ +++ CG + P+ G P+E L +
Sbjct: 377 GEGN-----LELNWLLGKDVQCTKAPVPIDDNF-CGLDIN-QPLGGSTPVEGLTLYTTSR 429
Query: 396 P-VSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQ--GQVYHSQQVGPPGSAISPDLLLD 452
+++VA+ +G+ + F+G G+L K+ G G Y V GS I D+
Sbjct: 430 DRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDGSPILRDMAFS 489
Query: 453 SSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQL 512
+LYV++ QV R+PV +C Q+ C CL + DP CGWC L C+R+ +C +A +
Sbjct: 490 IDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCSRRDKCQQAWEP 549
Query: 513 NQWLWSYEED-SHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSL- 570
N++ S + S +H S+ H R ++L V P L A CAFG+ +
Sbjct: 550 NRFAASISQCVSLAVHPSSISVSEHSRL----LSLVVSDAPDLSAG--IACAFGNLTEVE 603
Query: 571 AHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDV--TVAATNFSFYDCSAVQALE 628
V G V C++P VP+ P D + L L ++ +T F FY+CSA Q
Sbjct: 604 GQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIFVSTEFKFYNCSAHQL-- 661
Query: 629 AAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGLA 688
C +CV S +RCHWC + C + + T S QE I + CPQ+
Sbjct: 662 ----CLSCVNSAFRCHWCKYRNLCTH-------DPTTCSFQEGRINISED--CPQLVPTE 708
Query: 689 GPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHCQ 748
L+PVG + L+ RNL + + C L + G + +PA +S + CQ
Sbjct: 709 -EILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPAL----RFNSSSVQCQ 763
Query: 749 AHQF-YPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGC 807
+ Y M L V V +DN L V LY CA C C A+R C
Sbjct: 764 NSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCLKADRKFEC 823
Query: 808 LWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEPLTGPPEGGLALTILGSN 859
WC+ G+ C C + L C P I + ++GPPEGG +TI G N
Sbjct: 824 GWCS-GERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGVN 882
Query: 860 LGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTT-GPVRVAIKSQPPGI- 917
LG F+++ + V VA PC P P Y + +IVC A GTT GPVR+ I P
Sbjct: 883 LGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVGTTSGPVRLCIGECKPEFM 942
Query: 918 --SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCP 975
S Q +T+ +P +LSL+P GP++GGT +TI G +L G + + ++G Q C
Sbjct: 943 TKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSVAVYLGNQTCEFYGRSMS 1002
Query: 976 EAIVCRTRPQA---APGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRL 1032
E IVC + P + P +V V H L F Y +P++ EP S G
Sbjct: 1003 E-IVCVSPPSSNGLGPVPVSVSVDRAHVDSNL---QFEYIDDPRVQRIEPEWSIASGHTP 1058
Query: 1033 IRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLL 1092
+ + G LDV+Q P + V V
Sbjct: 1059 LTITGFNLDVIQEPRIRVKFNGKESVN--------------------------------- 1085
Query: 1093 QCSTVCSVNSSSLLLCRSPAVPDR--------AHPQRVFFTLDNVQVDFASASGGQGFLY 1144
VC V +++ L C +P++ P F +NVQ F+Y
Sbjct: 1086 ----VCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFNNVQS--LLIYNDTKFIY 1139
Query: 1145 QPNPRLAPLSREGPARPYRLKPGHVLDVEGEGL---NLGISKEEVRVHIGRGECLVKTLT 1201
PNP LS P KPG + ++G+ L G +K V IG C V T++
Sbjct: 1140 YPNPTFELLS---PTGVLDQKPGSPIILKGKNLCPPASGGAKLNYTVLIGETPCAV-TVS 1195
Query: 1202 RTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMG 1261
T L CEPP N +G + +V +G + + G V ++ S + A + G
Sbjct: 1196 ETQLLCEPP-------NLTGQHKVMVHVGGMVFSPGSVSVISD---SLLTLPAIVSIAAG 1245
Query: 1262 AAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSS 1321
++L+ V+++ + Y+ KS++ +++ +Q+++LE+ V +C++ F +L T++ +L+S
Sbjct: 1246 GSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALECKEAFAELQTDINELTS 1305
Query: 1322 DLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKL 1381
DL+ SGIP+LDYRTYA R FPG P+ + E G V + L + L+N+K+
Sbjct: 1306 DLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQ--HVEKALKLFAQLINNKV 1363
Query: 1382 FLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHR--NP 1439
FLLT I TLE Q SFS RDR +VASL+ L G+LEY TD+++ LL DL + +P
Sbjct: 1364 FLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLENKNHP 1423
Query: 1440 KLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKR 1499
KL+LRRTE++ EK+LTNW + L+ FL+E AGEPL+ML+ AI+ Q++KGP+DA+TG+A+
Sbjct: 1424 KLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARY 1483
Query: 1500 TLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQV 1559
+L++ +L+R+ +E++ L L V P + +P +VL+ DTITQVKEK+LD V
Sbjct: 1484 SLSEDKLIRQQIEYKTLILNC-VNPD------NENSPEIPVKVLNCDTITQVKEKILDAV 1536
Query: 1560 YKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVG 1619
YK P+SQRP +DLEWR G + L DED+T+ + WKRLNTL HY+V D + V
Sbjct: 1537 YKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWKRLNTLMHYQVSDRSVVA 1596
Query: 1620 LVPQ------LHRGSTISQSLAQRCP-----------LGENIPTLEDGEEGGVCLWHLVK 1662
LVP+ + ++IS++ R L P + E GV +WHLVK
Sbjct: 1597 LVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAPMITPDLESGVKVWHLVK 1656
Query: 1663 ATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV---N 1718
+ + ++E R +K + EIYLTRLL+ KGTLQKFVDD F+ + S
Sbjct: 1657 NHDHGD----------QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETLFSTVHRG 1706
Query: 1719 RPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDN 1778
+P+A+KY+FD LDE A++H I D H WK+N L LRFWVN +KNPQ +FD+
Sbjct: 1707 SALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKGSI 1766
Query: 1779 VDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASY 1838
DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK VERYYADI + S
Sbjct: 1767 TDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKSWVERYYADIAKLPAISD 1826
Query: 1839 QEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQV 1898
Q+MN+ LAE S + + L AL E+Y+++ +Y +++I ALE+D ++ +LA +++Q+
Sbjct: 1827 QDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALEQDEQARRQRLAYKVEQL 1886
>gi|157694524 plexin D1 [Homo sapiens]
Length = 1925
Score = 962 bits (2488), Expect = 0.0
Identities = 696/2005 (34%), Positives = 992/2005 (49%), Gaps = 238/2005 (11%)
Query: 24 PFGLCLLLLLLSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQLS-PELQ 82
P L LLLLL + L RF +P T N+ AL GT+Y+ AVNRL+QLS L
Sbjct: 30 PVPLLLLLLLGAARAGALEIQRRFPSPTPT-NNFALDGAAGTVYLAAVNRLYQLSGANLS 88
Query: 83 LEAVAVTGPVIDSPDC-VPFRDPAECPQAQ-LTDNANQLLLVSSRAQELVACGQVRQGVC 140
LEA A GPV DSP C P A C + LTDN N++L + +V CG + QG C
Sbjct: 89 LEAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVVCGSIYQGFC 148
Query: 141 ETRRLGDVAEVLYQ---AEDPGDGQFV-------AANTPGVATVGLVVPLP---GRDLLL 187
+ RR G+++ V + A P + V AAN P +TVGLV+P G LL
Sbjct: 149 QLRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLL 208
Query: 188 VARGLAGKLSA--------------GVPPLAIRQLAGSQPF----------SSEGLGRLV 223
V G S+ P +AIR L S + + ++
Sbjct: 209 VGATYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIK 268
Query: 224 VGDFSDYNNSYVGAFAD-------ARSAYFVFRRRGARA---QAEYRSYVARVCL----- 268
G + +V AF A+S ++ ARA +++ RS +AR+CL
Sbjct: 269 QGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAG 328
Query: 269 GDTNLY--SYVEVPLACQG-------QGLIQAAFLAPGTLLGVF-----AAGPRGTQAAL 314
GD SY+++ L C G + + F A L VF + R AAL
Sbjct: 329 GDAKKLTESYIQLGLQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAAL 388
Query: 315 CAFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRC---VTLPLDSPESYPCG 371
CAF ++ A++ AR C+ ++ V+ G C + + L PE CG
Sbjct: 389 CAFRFADVRAAIRAARTACFVEPAPDVVAVLDSVVQ-GTGPACERKLNIQLQ-PEQLDCG 446
Query: 372 DEHTPSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQ 431
H P++ QPL+ P+ + +++VA + + FLG G+L K+ L+ S
Sbjct: 447 AAHLQHPLSILQPLKATPVFR-APGLTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQV 505
Query: 432 VYHSQQVGPPGSAISPDLLLDSSGS-HLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPL 490
V G + + D + S +LY++T+HQ+ R+ VAAC C C+ A D
Sbjct: 506 VSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAY 565
Query: 491 CGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVP- 549
CGWC L+ RCT + C + Q + W + E S C + L RQE + L +
Sbjct: 566 CGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISG 625
Query: 550 RLPILDADEYFHCAFGD-YDSLAHVEGPHVA-----CVTPPQDQVPLNPPGTDHVTVPLA 603
LP L E C +G+ ++A V GP C P+DQ P PP DHVTV ++
Sbjct: 626 SLPSLSGME-MACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMS 684
Query: 604 LMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGER 663
+ + NF+ YDCS + C +C+ + W C WC Q CV +
Sbjct: 685 VRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQ------- 737
Query: 664 TIYSAQEVDIQVRGPGACPQVEGLAGPHL-VPVGWESHLALRVRNLQHFRGLPASFHCWL 722
S E P CP+ L P VP G ++ + + N F+G A+ C
Sbjct: 738 ---SRCEASPNPTSPQDCPRT--LLSPLAPVPTGGSQNILVPLANTAFFQG--AALECSF 790
Query: 723 ELPGELRGLPATLEETAGDSGLIHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALY 782
GL E + ++ C + + + P+ + + A+ LD+ +
Sbjct: 791 -------GLEEIFEAVWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMT 843
Query: 783 VILYDCAMGHPDCSHCQAANRSLG--CLWCADGQPACRY-GPLCPPGAVELLCPAPSIDA 839
V++Y+CAMG PDCS C LG C+W +DG CR GPL P CPAP I A
Sbjct: 844 VMVYNCAMGSPDCSQC-LGREDLGHLCMW-SDG---CRLRGPLQPMAGT---CPAPEIRA 895
Query: 840 VEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAP 899
+EPL+GP +GG LTI G NLGR +DV + V + C P P Y S IVCVT PAP
Sbjct: 896 IEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAP 955
Query: 900 NGTTGPVRVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTS 959
+G V V + G S F+Y P++ SL P GP+AGGT++TI G L G
Sbjct: 956 GPLSGVVTVNASKE--GKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQ 1013
Query: 960 AFVGG-QPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLV 1018
V PC L +I C A P V V F F Y NP +
Sbjct: 1014 VLVNDTDPCTELMRT-DTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVIT 1072
Query: 1019 AAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPA 1078
A P S GGR I V G +VQ ++V ++P
Sbjct: 1073 AISPRRSPVSGGRTITVAGERFHMVQNVSMAV-----------HHIGREP---------- 1111
Query: 1079 ADPQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAVPDRAHPQRVFFT-----LDNVQV-- 1131
T+C V +S+L+ C SP A FF D V V
Sbjct: 1112 -----------------TLCKVLNSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAE 1154
Query: 1132 ---DFASASGGQGFL--YQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEV 1186
D A G F Y PNP+ + RE + + +P L + E +LG+ E
Sbjct: 1155 ELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEP-LTLVIHKEQDSLGLQSHEY 1213
Query: 1187 RVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPP 1246
RV IG+ C ++ ++ ++C + A LP +Q+GN + +Q
Sbjct: 1214 RVKIGQVSCDIQIVSDRIIHCS--VNESLGAAVGQLP-ITIQVGNFNQTIATLQ------ 1264
Query: 1247 LSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCR 1306
L + + + +L+ +V+ L ++ KS++A R +QK L+Q+E +E+ + ++ R
Sbjct: 1265 LGGSETAIIVSIVICSVLLLLSVVAL-FVFCTKSRRAERYWQKTLLQMEEMESQIREEIR 1323
Query: 1307 KEFTDLMTEMTDLSSDLEGS-GIPFLDYRTYAERAFFP------------------GHGG 1347
K F +L T+MTDL+ +L S GIPFL+Y+ + R FFP G
Sbjct: 1324 KGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGS 1383
Query: 1348 CPLQPKPEGPGE----DGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCH 1403
Q GE + + +G++ S+LLN+K FL+ +H LE+Q F+ RDRC
Sbjct: 1384 SQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCS 1443
Query: 1404 VASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLTNWLSICLY 1463
+ASLL++ALHGKLEY T IM+ LL DL +NPKLMLRRTE++VEK+LTNW+SIC+Y
Sbjct: 1444 LASLLTIALHGKLEYYTSIMKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSICMY 1503
Query: 1464 AFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVLVG 1523
+ LRE GEP ++L AI+ Q++KG +DA+TGKA+ TLN+ LLRE++E +P L V
Sbjct: 1504 SCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNVSF- 1562
Query: 1524 PGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRSGLA 1583
G G M + R +DTDT+TQVKEK+L+ K P+SQ P +DLEW +
Sbjct: 1563 QGCG-------MDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASST 1615
Query: 1584 GHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLAQRCPLGEN 1643
L D D TSV ++ K+LNTL HYK+P+GA++ + + +T+ +
Sbjct: 1616 QSYILRDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKKDNTLGR----------- 1664
Query: 1644 IPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTRLLSMKGTL 1703
+ L+ + +HLV T+E K R+ R K +PEIYLTRLLS KGTL
Sbjct: 1665 VKDLDTEK-----YFHLVLPTDELAEPKKS-----HRQSHRKKVLPEIYLTRLLSTKGTL 1714
Query: 1704 QKFVDDTFQAILSV--NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWV 1761
QKF+DD F+AILS+ ++P P+AVKY FD L+E AEK GI DP TLHIWKTNSL LRFWV
Sbjct: 1715 QKFLDDLFKAILSIREDKP-PLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWV 1773
Query: 1762 NALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQ 1821
N LKNPQ +FD+ +D++DA L+VIAQ FID+C+ S+ ++G+DSP NKLLYA+EIP Y++
Sbjct: 1774 NILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRK 1833
Query: 1822 MVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALE 1881
+V+RYY I+ +P S QEMN+ LAE S Y + + A+ E+Y + RY QI++ALE
Sbjct: 1834 IVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALE 1893
Query: 1882 EDPVGQKLQLACRLQQVAALVENKV 1906
+P ++ QL + +QV AL+E+ +
Sbjct: 1894 ANPTARRTQLQHKFEQVVALMEDNI 1918
>gi|49355818 plexin A1 [Homo sapiens]
Length = 1873
Score = 955 bits (2468), Expect = 0.0
Identities = 662/1958 (33%), Positives = 982/1958 (50%), Gaps = 219/1958 (11%)
Query: 47 FSAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAE 106
FSA + L HL + G +YVGAVNR+++LS L L VTGPV D+ C P
Sbjct: 21 FSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQS 80
Query: 107 CPQAQ-LTDNANQLLLVSSRAQELVACGQVRQGVCETRRLGDV---AEVLYQAEDPGDGQ 162
CP TDN N+LLL+ A L+ACG QG+C+ RL D+ E ++ E
Sbjct: 81 CPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSV 140
Query: 163 FVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQP--------F 214
A + GV G P G+ L V + GK S P L+ R+L ++ +
Sbjct: 141 QEAGSMAGVLIAG--PPGQGQAKLFVGTPIDGK-SEYFPTLSSRRLMANEEDADMFGFVY 197
Query: 215 SSEGLGRLV------VGDFSDYNNSYVGAFADARSAYFV-------FRRRGARAQAEYRS 261
E + + + F ++ YV +F + Y++ A + + S
Sbjct: 198 QDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTS 257
Query: 262 YVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA-PGTLLG--------------V 302
+ R+C+ D YSYVE P+ C+ G L+Q A+L+ PG L V
Sbjct: 258 KIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTV 317
Query: 303 FAAGPRGT-----QAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRC 357
FA G + ++ALC F + + +++ + CY G+ S E G C
Sbjct: 318 FAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGK-LSLPWLLNKELG----C 372
Query: 358 VTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPL-LKLGQPVSAVAALQADGHMIAFLGDT 416
+ PL + + CG + P+ G +E PL + ++AVAA G + F G
Sbjct: 373 INSPLQIDDDF-CGQDFN-QPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTR 430
Query: 417 QGQLYKVFLH----GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVA 472
G++ K+ + G + + + V GS I DL+L + +LY +T QV R+PV
Sbjct: 431 SGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVE 490
Query: 473 ACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLL 532
+C Q+ C CL ++DP CGWCVL C+R+ C RA + ++ + C +Q +
Sbjct: 491 SCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAADLLQ---C--VQLTV 545
Query: 533 PGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDY-DSLAHVEGPHVACVTPPQDQV-PL 590
+ QV L + + D +C+F D+ +S + +E + C +P +V P+
Sbjct: 546 QPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHCRSPSAREVAPI 605
Query: 591 NPPGTDHVTVPLALMFEDV--TVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQ 648
D V L L ++ A+ +F FY+CS Q+ C +CV + CHWC
Sbjct: 606 TRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQS------CLSCVNGSFPCHWCKY 659
Query: 649 SSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGLAGPHL-VPVGWESHLALRVRN 707
C + + ++ +V CPQ+ L + VPVG + L RN
Sbjct: 660 RHVCTHN---------VADCAFLEGRVNVSEDCPQI--LPSTQIYVPVGVVKPITLAARN 708
Query: 708 LQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHCQAHQF-YPSMSQRELPVPIY 766
L + + C +PG PA + +S + CQ + Y +LPV +
Sbjct: 709 LPQPQSGQRGYECLFHIPGS----PARVTALRFNSSSLQCQNSSYSYEGNDVSDLPVNLS 764
Query: 767 VTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGCLWC-ADGQPACRYGPLCPP 825
V +DN + LY C C C A+ C WC A+ + + R+
Sbjct: 765 VVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECGWCVAERRCSLRHHCAADT 824
Query: 826 GAVEL-------LCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPC 878
A + C P I + P TGP +GG LTI G NLG F DV+ V V C
Sbjct: 825 PASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLC 884
Query: 879 NPEPSLYRTSARIVCVTSPAPN--GTTGPVRVAIKSQPP---GISSQHFTYQDPVLLSLS 933
+P S Y ++ +IVC A + V V ++ P +S + FT+ P +S
Sbjct: 885 SPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVS 944
Query: 934 PRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAV 993
P GP +GGT + I G HL G + + VGG+PC E I C T P +PG A +
Sbjct: 945 PSRGPLSGGTWIGIEGSHLNAGSDVAVSVGGRPCSFSWRNSRE-IRCLTPPGQSPGSAPI 1003
Query: 994 LVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLE 1053
++ AQ T + YT +P ++ +P S GG L+ V GT L V+ P +
Sbjct: 1004 IININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRIRA--- 1060
Query: 1054 ADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAV 1113
+ GG ++ C V + + ++CR+P+V
Sbjct: 1061 --------------------------------KYGG--IERENGCLVYNDTTMVCRAPSV 1086
Query: 1114 --PDRAHPQ------RVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPARPYRLK 1165
P R+ P+ + F +DNV+ S FLY P+P L PLS P LK
Sbjct: 1087 ANPVRSPPELGERPDELGFVMDNVRSLLVLNS--TSFLYYPDPVLEPLS---PTGLLELK 1141
Query: 1166 PGHVLDVEGEGL---NLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGSGL 1222
P L ++G L G S+ V IG C + T++ T L CE P N +G
Sbjct: 1142 PSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTL-TVSETQLLCEAP-------NLTGQ 1193
Query: 1223 PQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQ 1282
+ V+ G + + G +Q ++ S + A G+G G +L+ ++ + + Y+ KS+
Sbjct: 1194 HKVTVRAGGFEFSPGTLQVYSD---SLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRD 1250
Query: 1283 ALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFF 1342
A R +++ +Q+++LE+ V +C++ F +L T++ +L++DL+G+GIPFLDYRTYA R F
Sbjct: 1251 ADRTLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLF 1310
Query: 1343 PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRC 1402
PG P+ + E A V + LT LL K FLLT I TLE Q SFS RDR
Sbjct: 1311 PGIEDHPVLKEMEVQ------ANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRG 1364
Query: 1403 HVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVH--RNPKLMLRRTETMVEKLLTNWLSI 1460
+VASL+ AL G++EY T +++ LL DL + +PKL+LRRTE++ EK+LTNW +
Sbjct: 1365 NVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTF 1424
Query: 1461 CLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMV 1520
LY FL+E AGEPL+ML+ AI+ Q++KGP+DA+TG+A+ +L++ +L+R+ ++++ LTL
Sbjct: 1425 LLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNC 1484
Query: 1521 LVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRS 1580
V P A VP + LD DT+TQ KEK+LD YKG P+SQRP +DLEWR
Sbjct: 1485 -VNPENENAP------EVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQ 1537
Query: 1581 GLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQ------LHRGSTISQSL 1634
G + L DED+T+ N WKRLNTL HY+V DG++V LVP+ + ST ++SL
Sbjct: 1538 GRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTKSL 1597
Query: 1635 AQR----------CPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPAR 1684
++ L P + E G LWHLVK + L +RE R
Sbjct: 1598 SRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDH----------LDQREGDR 1647
Query: 1685 -AKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV---NRPIPIAVKYLFDLLDELAEKHG 1740
+K + EIYLTRLL+ KGTLQKFVDD F+ I S +P+A+KY+FD LDE A+KH
Sbjct: 1648 GSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHQ 1707
Query: 1741 IEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHK 1800
I D H WK+N L LRFWVN +KNPQ +FD+ + DA L+V+AQTF+DSC+TSEHK
Sbjct: 1708 IHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHK 1767
Query: 1801 VGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLE 1860
+G+DSP NKLLYA++IP YK VERYYADI + S Q+M++ LAE S + S + +
Sbjct: 1768 LGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLHLSQFNSMS 1827
Query: 1861 ALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQV 1898
AL E+Y++I +Y D+I++ALE+D ++ +L +L+QV
Sbjct: 1828 ALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQV 1865
>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
Length = 1894
Score = 927 bits (2395), Expect = 0.0
Identities = 655/1991 (32%), Positives = 992/1991 (49%), Gaps = 246/1991 (12%)
Query: 33 LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 87
LL+ P PL+ R P NHL + G +Y+GAVNR+++LS +L++
Sbjct: 25 LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
Query: 88 VTGPVIDSPDCVPFRDPAECPQA-QLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 146
TGP D+P C P R C + T+N N++LL+ + L+ACG + QG+C+ RL
Sbjct: 85 ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
Query: 147 DVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRD-LLLVARGLAGKLSAGVPPLAI 205
D+ + L + + N G + G++V D L +A + GK P ++
Sbjct: 145 DLFK-LGEPYHKKEHYLSGVNESG-SVFGVIVSYSNLDDKLFIATAVDGKPEY-FPTISS 201
Query: 206 RQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYFVFR 249
R+L + ++G+ V D D++ YV F+ YF+
Sbjct: 202 RKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTL 259
Query: 250 RR-------GARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLAP-G 297
+ + Y S + R+C DT SYVEVP+ C+ G L+QAA+L+ G
Sbjct: 260 QPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAG 319
Query: 298 TLLG--------------VFAAGPRGT-----QAALCAFPMVELGASMEQARRLCYTAGG 338
+LG VF+ G + ++ALC F + ++ +++ + CY
Sbjct: 320 AVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY---- 375
Query: 339 RGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPV- 397
RG + A ++ C + L +++ CG + PL V +++ G PV
Sbjct: 376 RGEGTLDLAWLKVKDIP-CSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIPVF 425
Query: 398 -------SAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQV--YHSQQVGPPGSAISPD 448
++V A H +AF+G G+L K+ + G +G Y + QV PG + D
Sbjct: 426 TEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLR-D 484
Query: 449 LLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGR 508
+ LY+++ Q+ R+PV +C Q+ C CL + DP CGWCVL CTRK +C R
Sbjct: 485 MAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKERCER 544
Query: 509 AGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQ---EQGQVTLSVPRLPILDADEYFHCAFG 565
+ + ++ E C+ + HP Q V L + + + +C F
Sbjct: 545 SKEPRRFA---SEMKQCVRLTV-----HPNNISVSQYNVLLVLETYNVPELSAGVNCTFE 596
Query: 566 DYDSL-AHVEGPHVACVTPPQDQVP-LNPPGTDHVTVPLALMFED--VTVAATNFSFYDC 621
D + V G + C +P +VP + DH V L L ++ +T A+T+F FY+C
Sbjct: 597 DLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMTFASTSFVFYNC 656
Query: 622 SAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGAC 681
S + C +CV S +RCHWC Y C +T S QE +++ P C
Sbjct: 657 SVHNS------CLSCVESPYRCHWCK------YRHVCTHDPKTC-SFQEGRVKL--PEDC 701
Query: 682 PQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGD 741
PQ+ + LVPV + L+ +NL + + C L + G + +PA +
Sbjct: 702 PQLLRV-DKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPAL----RFN 756
Query: 742 SGLIHCQAHQF-YPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQA 800
S + CQ + Y M LPV + V +DN V LY C C C
Sbjct: 757 SSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLK 816
Query: 801 ANRSLGCLWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEPLTGPPEGGLA 852
A+ C WC G C CP + L C P I + P+TGP EGG
Sbjct: 817 ADPDFACGWC-QGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTK 875
Query: 853 LTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPA-PNGTTGPVRVAIK 911
+TI G NLG F D+ V VA C+P Y + +IVC A P+ G V + +
Sbjct: 876 VTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVA 935
Query: 912 SQPPGI---SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCP 968
P SSQ + + L L P GP +GGTQ+TI G +L G N G QPC
Sbjct: 936 VCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPC- 994
Query: 969 ILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQ--RTLLASPFRYTANPQLVAAEPSASF 1026
+ P IVC T E V V A+ + L+ F+Y +P +V EP S
Sbjct: 995 LFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAKIHQDLV---FQYVEDPTIVRIEPEWSI 1051
Query: 1027 RGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQ 1086
G I V GT LD++Q P +++A
Sbjct: 1052 VSGNTPIAVWGTHLDLIQNP----------QIRAKH------------------------ 1077
Query: 1087 LGGGLLQCSTVCSVNSSSLLLCRSPAV---PDRA-----HPQRVFFTLDNVQVDFASASG 1138
G + +C V +++ + C++PA+ PD P+ F LDNVQ
Sbjct: 1078 ---GGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQS--LLILN 1132
Query: 1139 GQGFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVH----IGRGE 1194
F Y PNP GP+ LKPG + ++G+ L ++ V+++ +G
Sbjct: 1133 KTNFTYYPNPVFEAF---GPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKP 1189
Query: 1195 CLVKTLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1254
C V T++ L CE P N G + + ++G ++ + G V + PLS + A
Sbjct: 1190 CTV-TVSDVQLLCESP-------NLIGRHKVMARVGGMEYSPGMVYIAPDSPLS---LPA 1238
Query: 1255 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1314
+ + +LI ++ + + Y+ KS+++ +++ +Q+++LE+ V +C++ F +L T
Sbjct: 1239 IVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQT 1298
Query: 1315 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1374
++ +L+SDL+G+GIPFLDYRTY R FPG P+ E PG V +GL +
Sbjct: 1299 DIHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQE--RVEKGLKLFA 1356
Query: 1375 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1434
L+N+K+FLL+ I TLE Q SFS RDR +VASL+ L KLEY TD+++ LL DL
Sbjct: 1357 QLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKN 1416
Query: 1435 VH--RNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDA 1492
+ +PKL+LRRTE++ EK+LTNW + LY FL+E AGEPL+ LF AI+ Q++KGP+DA
Sbjct: 1417 LESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDA 1476
Query: 1493 VTGKAKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1552
+TG+A+ +L++ +L+R+ ++++ L L + + ++ VP ++L+ DTITQVK
Sbjct: 1477 ITGEARYSLSEDKLIRQQIDYKTLVLSCV-------SPDNANSPEVPVKILNCDTITQVK 1529
Query: 1553 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1612
EK+LD ++K P S RP +DLEWR G + L DED+T+ +N WKRLNTL HY+V
Sbjct: 1530 EKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQV 1589
Query: 1613 PDGATVGLVPQ------LHRGSTISQSLAQRCP-----------LGENIPTLEDGEEGGV 1655
PDG+ V LV + ST+S++ A + L P + E GV
Sbjct: 1590 PDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGV 1649
Query: 1656 CLWHLVKATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQKFVDDTFQAI 1714
+WHLVK E + ++E R +K + EIYLTRLL+ KGTLQKFVDD F+ I
Sbjct: 1650 KMWHLVKNHEHGD----------QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETI 1699
Query: 1715 LSV---NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIF 1771
S +P+A+KY+FD LDE A+KHGI DP H WK+N L LRFWVN +KNPQ +F
Sbjct: 1700 FSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVF 1759
Query: 1772 DVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIR 1831
D+ + DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK VERYY+DI
Sbjct: 1760 DIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIG 1819
Query: 1832 QSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQL 1891
+ S Q+MN+ LAE S + + + + AL E+++++ +Y ++I+ L+ D K +L
Sbjct: 1820 KMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKL 1879
Query: 1892 ACRLQQVAALV 1902
A +L+QV L+
Sbjct: 1880 AYKLEQVITLM 1890
>gi|59710104 plexin A3 [Homo sapiens]
Length = 1871
Score = 913 bits (2359), Expect = 0.0
Identities = 645/1988 (32%), Positives = 976/1988 (49%), Gaps = 232/1988 (11%)
Query: 27 LCLLLLLLSPPPLPLTGA------HRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPE 80
+CLLLLL L + GA F +TTL HLA+ G ++VGAVNR+F+L+P
Sbjct: 4 VCLLLLLF----LAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPN 59
Query: 81 LQLEAVAVTGPVIDSPDCVPFRDPAECPQAQL-TDNANQLLLVSSRAQELVACGQVRQGV 139
L VTGPV D+ C P C DN N+LLL+ A+ LVACG + QG+
Sbjct: 60 LTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGI 119
Query: 140 CETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAG 199
C+ RL D+ + L + + A P +V G L V + GK S
Sbjct: 120 CQFLRLDDLFK-LGEPHHRKEHYLSGAQEPDSMAGVIVEQGQGPSKLFVGTAVDGK-SEY 177
Query: 200 VPPLAIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARS 243
P L+ R+L + S + LV D + ++ Y+ F A
Sbjct: 178 FPTLSSRKLISDE--DSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASF 235
Query: 244 AYFVFRRRGAR-------AQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAA 292
YF+ + + + + S + R+C GD+ YSYVE P+ C +G L+Q+A
Sbjct: 236 VYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSA 295
Query: 293 FLA-PGTLLG--------------VFAAGPRGT-----QAALCAFPMVELGASMEQARRL 332
LA PG LL +F+ G + Q LC F + + A + + +
Sbjct: 296 HLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQS 355
Query: 333 CYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLK 392
CY RG G C+ P+ ++ CG P+ G +E PLL
Sbjct: 356 CY----RG-EGTLALPWLLNKELPCINTPMQINGNF-CGLVLN-QPLGGLHVIEGLPLLA 408
Query: 393 LGQP-VSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLL 451
+++VAA H + F+G G L KV + G Q + GS I DLL
Sbjct: 409 DSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLF 468
Query: 452 DSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQ 511
H+Y+L+ QV ++PV C Q+ CA+CL + DP CGWCVL+ RC R+G C A
Sbjct: 469 SPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASA 528
Query: 512 LNQWLWSYEEDSHCLHIQSLLPGHHPRQEQG-QVTLSVPRLPILDADEYFHCAF---GDY 567
+ + EE S C+ ++ + P + G Q+T+++ +P L A CAF +
Sbjct: 529 PHGFA---EELSKCVQVR-VRPNNVSVTSPGVQLTVTLHNVPDLSAG--VSCAFEAAAEN 582
Query: 568 DSLAHVEGPHVACVTPPQDQVPLNPPGTDHV-TVPLALMFEDVTV--AATNFSFYDCSAV 624
+++ G + C +P ++ G TV L L+ ++ V A +F FY+CS +
Sbjct: 583 EAVLLPSG-ELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVL 641
Query: 625 QALEAAAPCRACVGSIWRCHWCPQSSHCVYGEH-CPEGERTIYSAQEVDIQVRGPGACPQ 683
Q+ C +CVGS + CHWC C H C E ++S P CP+
Sbjct: 642 QS------CMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHS----------PEGCPE 685
Query: 684 VEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSG 743
+ +G L+PVG L LR +NL + ++ C + + G + +PA +S
Sbjct: 686 ILP-SGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAV----RFNSS 740
Query: 744 LIHCQ-AHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAAN 802
+ CQ A Y + + V +D + +LY C P C C A+
Sbjct: 741 SVQCQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKAD 800
Query: 803 RSLGCLWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEPLTGPPEGGLALT 854
C WC + C+ CP + C P I + PL GP EGG +T
Sbjct: 801 PRFNCGWCIS-EHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVT 859
Query: 855 ILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVT--SPAPNGTTGPVRVAIKS 912
I+G NLG +V + VA CN P+ Y ++ RIVC S P+ GPV + +
Sbjct: 860 IVGDNLGLLSREV--GLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGD 917
Query: 913 QPPGI---SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPI 969
S Q +++ P +SP GP +GGT+LTI G L G + V C
Sbjct: 918 CSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQF 977
Query: 970 LEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGG 1029
+ + P +A + + A + + YT +P + EP+ S G
Sbjct: 978 VRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIING 1037
Query: 1030 GRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGG 1089
I V GT L VQ P + RA+ +
Sbjct: 1038 STAITVSGTHLLTVQEPRV-------------RAKYRG---------------------- 1062
Query: 1090 GLLQCSTVCSVNSSSLLLCRSPAV--------PDRAHPQRVFFTLDNVQVDFASASGGQG 1141
++ + C V + + +LC++P + HP F LD+VQ A +
Sbjct: 1063 --IETTNTCQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQT--ARSLNRSS 1118
Query: 1142 FLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGL---NLGISKEEVRVHIGRGECLVK 1198
F Y P+P PL GP+ +KPG + ++G+ L G S+ V IG C +
Sbjct: 1119 FTYYPDPSFEPL---GPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSL- 1174
Query: 1199 TLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGV 1258
T++ T L C+ P+ +G +V +G ++ LG + AE L+ + A G+
Sbjct: 1175 TVSDTQLLCDSPSQ-------TGRQPVMVLVGGLEFWLGTLHISAERALT---LPAMMGL 1224
Query: 1259 GMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTD 1318
G +L+ A+ + + Y+ K++ A R +++ +Q+++LE+ V +C++ F +L T++ +
Sbjct: 1225 AAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINE 1284
Query: 1319 LSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLN 1378
L++ ++ IPFLDYRTYA R FPG P+ + + P V + L LL+
Sbjct: 1285 LTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTP------PNVEKALRLFGQLLH 1338
Query: 1379 SKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVH-- 1436
S+ F+LT IHTLE Q SFS RDR VASL +AL +L+Y T +++ LL DL +
Sbjct: 1339 SRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESK 1398
Query: 1437 RNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGK 1496
+PKL+LRRTE++ EK+LTNW + L+ FL+E AGEPL++L+ AI+ Q++KGP+DA+TG+
Sbjct: 1399 NHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGE 1458
Query: 1497 AKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVL 1556
A+ +L++ +L+R+ ++++ LTL + G A +VP +VL+ D+ITQ K+K+L
Sbjct: 1459 ARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSA-------QVPVKVLNCDSITQAKDKLL 1511
Query: 1557 DQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGA 1616
D VYKG P+SQRP +DLEWR G + L DED+T+ + WKRLN+L HY+V DG+
Sbjct: 1512 DTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGS 1571
Query: 1617 TVGLVPQ----------------LHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHL 1660
V LVP+ L R ++ ++ + L P + +E G LWHL
Sbjct: 1572 LVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHL 1631
Query: 1661 VKATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV-- 1717
VK + + RE R +K + EIYLTRLL+ KGTLQKFVDD F+ + S
Sbjct: 1632 VKNHDHAD----------HREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAH 1681
Query: 1718 -NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVS 1776
+P+A+KY+FD LDE A++ I DP H WK+N L LRFWVN +KNPQ +FD+ +
Sbjct: 1682 RGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKN 1741
Query: 1777 DNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPA 1836
DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK VERYY DI + +
Sbjct: 1742 SITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASI 1801
Query: 1837 SYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQ 1896
S Q+M++ L E S + S L AL ELY ++ +Y +I++AL+ D +K +L +L+
Sbjct: 1802 SDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLE 1861
Query: 1897 QVAALVEN 1904
Q+ +LV +
Sbjct: 1862 QIISLVSS 1869
>gi|5032223 plexin C1 [Homo sapiens]
Length = 1568
Score = 384 bits (986), Expect = e-106
Identities = 249/724 (34%), Positives = 389/724 (53%), Gaps = 56/724 (7%)
Query: 1172 VEGEGLNLGISKEEVRVHIGRGE-----CLVKTLTR----THLYCEPPAHAPQPANGSGL 1222
++ E N ISK+++ + + GE C + +TR T + C+ +
Sbjct: 863 IQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSS 922
Query: 1223 PQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQ 1282
+ V++GN++L V+ E+ P F + +L+ + + RHKSK+
Sbjct: 923 KKVRVKLGNLELY---VEQESVPSTWYFLIVLPV-------LLVIVIFAAVGVTRHKSKE 972
Query: 1283 ALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFF 1342
R + QLE LE+ + + R F +L + D+ +PFLDY+ +A R FF
Sbjct: 973 LSRKQSQ---QLELLESELRKEIRDGFAELQMDKLDVVDSF--GTVPFLDYKHFALRTFF 1027
Query: 1343 PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRC 1402
P GG + D + + LT L L+ +K FL+T+IHTLE+Q +FS +DRC
Sbjct: 1028 PESGGFTHIFTEDMHNRDAN--DKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRC 1085
Query: 1403 HVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLTNWLSICL 1462
AS L++AL KL YLT I+ L DL + PKLMLRRTE++VEKLLTNW+S+CL
Sbjct: 1086 LFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCL 1145
Query: 1463 YAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVLV 1522
FLRE GEP Y+L + +++KGPVD +T KA TLN+ LL + EF + L V+
Sbjct: 1146 SGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVF 1205
Query: 1523 GPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYK--GTPFSQRPSVHALDLEWRS 1580
+ + + + VLD DTI Q KEK+ G+P+ + ++ + LE +
Sbjct: 1206 EKIPENES-ADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQ--LNEIGLELQM 1262
Query: 1581 GLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLAQRCPL 1640
G L + + + ++ +LNT+ HY++ +G+T+ + ++ ++ + C L
Sbjct: 1263 GTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKKIANFTSDVEYSDDHCHL 1322
Query: 1641 GENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTRLLSMK 1700
L D E A ++ +G R R + K + E+YLT+LLS K
Sbjct: 1323 -----ILPDSE-----------AFQDVQGK-------RHRGKHKFK-VKEMYLTKLLSTK 1358
Query: 1701 GTLQKFVDDTFQAILSV-NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRF 1759
+ ++ F++I S+ N P A+KY FD LD AE I DP +HIWKTNSL LRF
Sbjct: 1359 VAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRF 1418
Query: 1760 WVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRY 1819
WVN LKNPQ +FD++ + ++D L+VIAQ F+D+ + +E ++G+++P NKLLYA++IP Y
Sbjct: 1419 WVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTY 1478
Query: 1820 KQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISA 1879
K+ V+ YY IR P S EM L + S + + + AL E+Y +I +Y+D+I++
Sbjct: 1479 KEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNK 1538
Query: 1880 LEED 1883
LE +
Sbjct: 1539 LERE 1542
Score = 83.6 bits (205), Expect = 2e-15
Identities = 75/293 (25%), Positives = 117/293 (39%), Gaps = 51/293 (17%)
Query: 381 GRQPLEVQPLLK---LGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQ-----V 432
G QP VQP+ + +++V + FLG GQL KV L + +
Sbjct: 357 GDQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVI 416
Query: 433 YHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCG 492
Y ++ P + PD + ++Y+ +V RI VA C + C+ CL A DP CG
Sbjct: 417 YEIKEETPVFYKLVPDPV---KNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCG 473
Query: 493 WCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLP 552
WC RCT +G C + L WL C IQ + +E+ VT+ P
Sbjct: 474 WCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQII----RSSKEKTTVTMVGSFSP 529
Query: 553 ILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVA 612
+ C + DS + C Q P T ++P ++DV+V
Sbjct: 530 -----RHSKCMVKNVDSSREL------CQNKSQ------PNRTCTCSIPTRATYKDVSVV 572
Query: 613 -----------ATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVY 654
+ F+F +CS+++ C ACV + C WC + C++
Sbjct: 573 NVMFSFGSWNLSDRFNFTNCSSLK------ECPACVET--GCAWCKSARRCIH 617
>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
Length = 522
Score = 120 bits (301), Expect = 1e-26
Identities = 128/481 (26%), Positives = 211/481 (43%), Gaps = 88/481 (18%)
Query: 33 LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 87
LL+ P PL+ R P NHL + G +Y+GAVNR+++LS +L++
Sbjct: 25 LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
Query: 88 VTGPVIDSPDCVPFRDPAECPQ-AQLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 146
TGP D+P C P R C + T+N N++LL+ + L+ACG + QG+C+ RL
Sbjct: 85 ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
Query: 147 DVAEVLYQAEDP--GDGQFVAANTPGVATVGLVVPLPG-RDLLLVARGLAGKLSAGVPPL 203
D L++ +P +++ + G++V D L +A + GK P +
Sbjct: 145 D----LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGK-PEYFPTI 199
Query: 204 AIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYF- 246
+ R+L + ++G+ V D D++ YV F+ YF
Sbjct: 200 SSRKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFL 257
Query: 247 ------VFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA- 295
V + Y S + R+C DT SYVEVP+ C+ G L+QAA+L+
Sbjct: 258 TLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSK 317
Query: 296 PGTLLG--------------VFAAGPRG-----TQAALCAFPMVELGASMEQARRLCYTA 336
G +LG VF+ G + ++ALC F + ++ +++ + CY
Sbjct: 318 AGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY-- 375
Query: 337 GGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQP 396
RG + A ++ C + L +++ CG + PL V +++ G P
Sbjct: 376 --RGEGTLDLAWLKV-KDIPCSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIP 423
Query: 397 V--------SAVAALQADGHMIAFLGDTQGQLYKVFLHGSQG---QVYHSQQVGPPGSAI 445
V ++V A H +AF+G G+L K F G QG Q + + PPG+ I
Sbjct: 424 VFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQEWIGVEGDPPGANI 483
Query: 446 S 446
+
Sbjct: 484 A 484
>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
Length = 492
Score = 112 bits (280), Expect = 3e-24
Identities = 119/455 (26%), Positives = 199/455 (43%), Gaps = 85/455 (18%)
Query: 33 LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 87
LL+ P PL+ R P NHL + G +Y+GAVNR+++LS +L++
Sbjct: 25 LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
Query: 88 VTGPVIDSPDCVPFRDPAECPQ-AQLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 146
TGP D+P C P R C + T+N N++LL+ + L+ACG + QG+C+ RL
Sbjct: 85 ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
Query: 147 DVAEVLYQAEDP--GDGQFVAANTPGVATVGLVVPLPG-RDLLLVARGLAGKLSAGVPPL 203
D L++ +P +++ + G++V D L +A + GK P +
Sbjct: 145 D----LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGK-PEYFPTI 199
Query: 204 AIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYF- 246
+ R+L + ++G+ V D D++ YV F+ YF
Sbjct: 200 SSRKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFL 257
Query: 247 ------VFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA- 295
V + Y S + R+C DT SYVEVP+ C+ G L+QAA+L+
Sbjct: 258 TLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSK 317
Query: 296 PGTLLG--------------VFAAGPRG-----TQAALCAFPMVELGASMEQARRLCYTA 336
G +LG VF+ G + ++ALC F + ++ +++ + CY
Sbjct: 318 AGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY-- 375
Query: 337 GGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQP 396
RG + A ++ C + L +++ CG + PL V +++ G P
Sbjct: 376 --RGEGTLDLAWLKV-KDIPCSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIP 423
Query: 397 V--------SAVAALQADGHMIAFLGDTQGQLYKV 423
V ++V A H +AF+G G+L K+
Sbjct: 424 VFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKM 458
>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
Length = 1390
Score = 100 bits (249), Expect = 1e-20
Identities = 144/595 (24%), Positives = 223/595 (37%), Gaps = 93/595 (15%)
Query: 795 CSHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALT 854
CS C +A + C WC D C C G P+I V P + P EGG LT
Sbjct: 526 CSQCLSAPPFVQCGWCHD---KCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLT 582
Query: 855 ILGSNLG----RAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAI 910
I G + G F + V + + C S T + C PA N + + I
Sbjct: 583 ICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLS-ESTMNTLKCTVGPAMNKHFN-MSIII 640
Query: 911 KSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPIL 970
+ F+Y DPV+ S+SP++GP AGGT LT+ G +L +G + +GG+ C L
Sbjct: 641 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTC-TL 699
Query: 971 EPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGG 1030
+ V + C T Q E AV + A R S F Y +P + P+ SF GG
Sbjct: 700 KSVSNSILECYTPAQTISTEFAVKLKIDLANRE--TSIFSYREDPIVYEIHPTKSFISGG 757
Query: 1031 RLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGG 1090
I G L+ V P + + + A AC
Sbjct: 758 STITGVGKNLNSVSVPRMVINVHE---------------------AGRNFTVACQHRSNS 796
Query: 1091 LLQCSTVCSVNSSSLLLCRSPAVPDRAHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRL 1150
+ C T S+ +L L + FF LD + + +Y NP
Sbjct: 797 EIICCTTPSLQQLNLQL---------PLKTKAFFMLDGILSKYFD------LIYVHNPVF 841
Query: 1151 APLSREGPARPYRLKPG--HVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCE 1208
P +P + G +VL+++G ++ K EV + +G C HL+ E
Sbjct: 842 KPFE-----KPVMISMGNENVLEIKGNDIDPEAVKGEV-LKVGNKSC-----ENIHLHSE 890
Query: 1209 PPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA-QAGVGMGAAVL-- 1265
A +P ++++ N +L + Q + L V+ Q G+ A V+
Sbjct: 891 --------AVLCTVPNDLLKL-NSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSI 941
Query: 1266 -IAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLE 1324
A +LLL K ++ ++D LV+ ++ + D + +S E
Sbjct: 942 STALLLLLGFFLWLKKRKQIKDLGSELVRYDA-------RVHTPHLDRLVSARSVSPTTE 994
Query: 1325 GSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNS 1379
+DYR FP ++G C V+ LT +S +L S
Sbjct: 995 MVSNESVDYRATFPEDQFP------------NSSQNGSCRQVQYPLTDMSPILTS 1037
Score = 79.0 bits (193), Expect = 4e-14
Identities = 116/525 (22%), Positives = 205/525 (39%), Gaps = 119/525 (22%)
Query: 66 LYVGAVNRLFQLSPE-LQLEAVAVTGPVIDSPDCVPFRD---PAECPQAQLTDNANQLLL 121
+++GA N ++ L+ E LQ A TGPV++ PDC P +D A DN N L+
Sbjct: 62 IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMALV 121
Query: 122 VSS-RAQELVACGQVRQGVCET-----RRLGDVAEVLY-----QAEDPGDGQFVAANTPG 170
V + +L++CG V +G C+ D+ ++ Q E+P + G
Sbjct: 122 VDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSALG 181
Query: 171 VATVGLVVPLPGRDLLL---VARGLAGKLSAGVP--PLAIRQLAGSQP---FSSEGLGRL 222
+ V +D + V + P +++R+L ++ F ++
Sbjct: 182 AKVLSSV-----KDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYID 236
Query: 223 VVGDFSD-YNNSYVGAFADARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPL 281
V+ +F D Y YV AF YF+ +R + + + R C ++ L+SY+E+PL
Sbjct: 237 VLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPL 296
Query: 282 AC-------------QGQGLIQAAFLA-PGT--------------LLGVFAAGPRGT--- 310
C + ++QAA+++ PG L GVFA +
Sbjct: 297 ECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEP 356
Query: 311 --QAALCAFPMVELG------ASMEQARRLCYTAGG-----------RGPSGAEEATVEY 351
++A+CAFP+ + + R L + G R SG E EY
Sbjct: 357 MDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEY 416
Query: 352 GVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQ----PVSAVAALQADG 407
+D L +GQ +++++
Sbjct: 417 RTEFTTALQRVD---------------------------LFMGQFSEVLLTSISTFIKGD 449
Query: 408 HMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLD---SSGSHLYVLTAH 464
IA LG ++G+ +V + S H + +SP+++++ + + V+T
Sbjct: 450 LTIANLGTSEGRFMQVVVSRSGPSTPHVNFL-LDSHPVSPEVIVEHTLNQNGYTLVITGK 508
Query: 465 QVDRIPV--AACPQFPDCASCLQAQDPL-CGWCVLQGRCTRKGQC 506
++ +IP+ C F C+ CL A + CGWC +C R +C
Sbjct: 509 KITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWC--HDKCVRSEEC 551
>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
sapiens]
Length = 1400
Score = 94.7 bits (234), Expect = 7e-19
Identities = 72/255 (28%), Positives = 109/255 (42%), Gaps = 29/255 (11%)
Query: 795 CSHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALT 854
C C A +GC WC + C CP + CP P + P +GP G LT
Sbjct: 533 CGRCLRAWHFMGCGWCGN---MCGQQKECPGSWQQDHCP-PKLTEFHPHSGPLRGSTRLT 588
Query: 855 ILGSNL----GRAFADVQYAVSVASRPCNPEP---SLYRTSAR------IVCVTSPAPNG 901
+ GSN + + V+V PC P P S R R C P
Sbjct: 589 LCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFECELEPLGTQ 648
Query: 902 TTGPVRVA--IKSQPPGISSQ--------HFTYQDPVLLSLSPRWGPQAGGTQLTIRGQH 951
GP V+ + + PPG + F++ +PVL+++ P +GP+AGGT LT+ GQ
Sbjct: 649 AVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAGGTCLTLEGQS 708
Query: 952 LQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRY 1011
L G + + V G C +L V ++C T P A + + G AQ + F+Y
Sbjct: 709 LSVGTSRAVLVNGTEC-LLARVSEGQLLCATPPGATVASVPLSLQVGGAQ-VPGSWTFQY 766
Query: 1012 TANPQLVAAEPSASF 1026
+P +++ P+ +
Sbjct: 767 REDPVVLSISPNCGY 781
Score = 61.2 bits (147), Expect = 9e-09
Identities = 144/656 (21%), Positives = 223/656 (33%), Gaps = 105/656 (16%)
Query: 23 PPFGLCLLLLLLSP-----------PPLPLTGAHRFSA----PNTTLNHLALAP------ 61
PP LLLLL P P P + F P+ + L A
Sbjct: 5 PPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVTYEGD 64
Query: 62 -GRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLL 120
++V NRL L P+L+ TGP D P C P D ++L
Sbjct: 65 RNESAVFVAIRNRLHVLGPDLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPGDTDTKVL 123
Query: 121 LVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQA----------EDPGDGQFVAANTPG 170
++ LV+CG QG C L ++ A P D A+ G
Sbjct: 124 VLDPALPALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDCPDCVASPLG 183
Query: 171 VATVGLVVPLPGRDLLLVARGLAGKLSAGVPP--LAIRQLAGSQPFSSEGLGRLVV--GD 226
VV VA L ++A P ++IR+L + G L V
Sbjct: 184 TRVT--VVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVALSVLPKH 241
Query: 227 FSDYNNSYVGAFADARSAYFVFRRRGARAQ--AEYRSYVARVCLGDTNLYSYVEVPLAC- 283
Y+ YV +F YF+ + + + + +AR+ + L Y E+ L C
Sbjct: 242 LVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPELGDYRELVLDCR 301
Query: 284 --------------QGQGLIQAAFLAP---------------GTLLGVFAAGPR-----G 309
Q +++ A AP L GVF G G
Sbjct: 302 FAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVFVTGKDGGPGVG 361
Query: 310 TQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYP 369
+ +CAFP+ L +++ C + G + S C P S
Sbjct: 362 PNSVVCAFPIDLLDTLIDEGVERCCESPVH--PGLRRGLDFFQSPSFCPNPPGLEALSPN 419
Query: 370 CGDEHTPSPIAGR-QPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGS 428
H P ++ +++ L V+A+ + D +A +G G++ +V L S
Sbjct: 420 TSCRHFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAHMGTMDGRILQVELVRS 479
Query: 429 QGQVYH--SQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPV--AACPQFPDCASCL 484
+ + + +G G + D + G HL + QV ++P+ C F C CL
Sbjct: 480 LNYLLYVSNFSLGDSGQPVQRD--VSRLGDHLLFASGDQVFQVPIQGPGCRHFLTCGRCL 537
Query: 485 QAQDPL-CGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQ 543
+A + CGWC GQ + S+++D H L HP G
Sbjct: 538 RAWHFMGCGWC-----------GNMCGQQKECPGSWQQD----HCPPKLTEFHP--HSGP 580
Query: 544 VTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNP-PGTDHV 598
+ S RL + ++ Y H + + V C P+D L P P D V
Sbjct: 581 LRGST-RLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFV 635
>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
Length = 1408
Score = 90.5 bits (223), Expect = 1e-17
Identities = 73/236 (30%), Positives = 102/236 (43%), Gaps = 12/236 (5%)
Query: 795 CSHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALT 854
CS C +A + C WC D C C G P+I V P + P EGG LT
Sbjct: 526 CSQCLSAPPFVQCGWCHD---KCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLT 582
Query: 855 ILGSNLG----RAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAI 910
I G + G F + V + + C S T + C PA N + + I
Sbjct: 583 ICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLS-ESTMNTLKCTVGPAMNKHFN-MSIII 640
Query: 911 KSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPIL 970
+ F+Y DPV+ S+SP++GP AGGT LT+ G +L +G + +GG+ C L
Sbjct: 641 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTC-TL 699
Query: 971 EPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASF 1026
+ V + C T Q E AV + A R S F Y +P + P+ SF
Sbjct: 700 KSVSNSILECYTPAQTISTEFAVKLKIDLANRE--TSIFSYREDPIVYEIHPTKSF 753
Score = 79.0 bits (193), Expect = 4e-14
Identities = 116/525 (22%), Positives = 205/525 (39%), Gaps = 119/525 (22%)
Query: 66 LYVGAVNRLFQLSPE-LQLEAVAVTGPVIDSPDCVPFRD---PAECPQAQLTDNANQLLL 121
+++GA N ++ L+ E LQ A TGPV++ PDC P +D A DN N L+
Sbjct: 62 IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMALV 121
Query: 122 VSS-RAQELVACGQVRQGVCET-----RRLGDVAEVLY-----QAEDPGDGQFVAANTPG 170
V + +L++CG V +G C+ D+ ++ Q E+P + G
Sbjct: 122 VDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSALG 181
Query: 171 VATVGLVVPLPGRDLLL---VARGLAGKLSAGVP--PLAIRQLAGSQP---FSSEGLGRL 222
+ V +D + V + P +++R+L ++ F ++
Sbjct: 182 AKVLSSV-----KDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYID 236
Query: 223 VVGDFSD-YNNSYVGAFADARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPL 281
V+ +F D Y YV AF YF+ +R + + + R C ++ L+SY+E+PL
Sbjct: 237 VLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPL 296
Query: 282 AC-------------QGQGLIQAAFLA-PGT--------------LLGVFAAGPRGT--- 310
C + ++QAA+++ PG L GVFA +
Sbjct: 297 ECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEP 356
Query: 311 --QAALCAFPMVELG------ASMEQARRLCYTAGG-----------RGPSGAEEATVEY 351
++A+CAFP+ + + R L + G R SG E EY
Sbjct: 357 MDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEY 416
Query: 352 GVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQ----PVSAVAALQADG 407
+D L +GQ +++++
Sbjct: 417 RTEFTTALQRVD---------------------------LFMGQFSEVLLTSISTFIKGD 449
Query: 408 HMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLD---SSGSHLYVLTAH 464
IA LG ++G+ +V + S H + +SP+++++ + + V+T
Sbjct: 450 LTIANLGTSEGRFMQVVVSRSGPSTPHVNFL-LDSHPVSPEVIVEHTLNQNGYTLVITGK 508
Query: 465 QVDRIPV--AACPQFPDCASCLQAQDPL-CGWCVLQGRCTRKGQC 506
++ +IP+ C F C+ CL A + CGWC +C R +C
Sbjct: 509 KITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWC--HDKCVRSEEC 551
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 62.0 bits (149), Expect = 5e-09
Identities = 114/508 (22%), Positives = 181/508 (35%), Gaps = 112/508 (22%)
Query: 55 NHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQA---- 110
+ LAL P L VGA N LF+LS ++ + + D Q+
Sbjct: 127 SQLALDPSGNQLIVGARNYLFRLS--------LANVSLLQATEWASSEDTRRSCQSKGKT 178
Query: 111 -QLTDNANQLLLVSSRAQELVACG-QVRQGVCETRRLGDVAEVLYQAE-------DPGDG 161
+ N ++L+V+ R ++ CG +C +R++G+++ + + DP
Sbjct: 179 EEECQNYVRVLIVAGR--KVFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHN 236
Query: 162 QFVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSEGLGR 221
++ G V+ GRD + L +G PPL Q ++S+ L
Sbjct: 237 STAVISSQGELYAATVIDFSGRDPAIYR-----SLGSG-PPLRTAQ------YNSKWLNE 284
Query: 222 LVVGDFSDYNNSYVGAFADARSAYFVFRRRGARAQAEYRSY--VARVCLGDTN------- 272
++V A+ AYF R Y VARVC D
Sbjct: 285 ----------PNFVAAYDIGLFAYFFLRENAVEHDCGRTVYSRVARVCKNDVGGRFLLED 334
Query: 273 -LYSYVEVPLACQGQGLI-------QAAFLAP--GTLLGVFAAGPRGTQA-ALCAFPMVE 321
++++ L C G + Q+AF P + GVF A A+CAF +
Sbjct: 335 TWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSA 394
Query: 322 LGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSP-ESYPCGDEHTPSP-- 378
+ + GP Y R LP+ +P ++ CG P
Sbjct: 395 ISQAFN------------GP-------FRYQENPRAAWLPIANPIPNFQCGTLPETGPNE 435
Query: 379 -IAGRQPLEVQPLLKLG---QPVSAVAALQADG----HMIAFLGDTQGQLYKVFLHGSQ- 429
+ R + Q L + QPV+ + D H++ L + LY V G++
Sbjct: 436 NLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTES 495
Query: 430 ---------------GQVYHSQQVGPPGSAIS-PDLLLDSSGSHLYVLTAHQVDRIPVAA 473
G V PPG L + S L+V V R+P+
Sbjct: 496 GTILKALSTASRSLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLER 555
Query: 474 CPQFPDCASCLQAQDPLCGWCVLQGRCT 501
C + +CL A+DP CGW Q RC+
Sbjct: 556 CAAYRSQGACLGARDPYCGWDGKQQRCS 583
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 61.2 bits (147), Expect = 9e-09
Identities = 124/503 (24%), Positives = 187/503 (37%), Gaps = 69/503 (13%)
Query: 57 LALAPGRGTLYVGAVNRLFQLSPE-LQLE-AVAVTGPVIDSPDCVPFRDPAECPQAQLTD 114
L L G LYVGA LF S E L+L+ A++ PV +C+ + + T+
Sbjct: 56 LTLTEPTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECI------QKGKNNQTE 109
Query: 115 NANQL-LLVSSRAQELVACGQVR-QGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVA 172
N + L A L CG Q C + + L E DG+ P
Sbjct: 110 CFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNM--LTFTLEHGEFE-DGKGKCPYDPAKG 166
Query: 173 TVGLVVPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSEGLGRLV-----VGDF 227
GL+V D L + L L G P+ +R + +E L + VG
Sbjct: 167 HAGLLV-----DGELYSATLNNFL--GTEPIILRNMGPHHSMKTEYLAFWLNEPHFVG-- 217
Query: 228 SDYNNSYVGAFA-DARSAYFVFRRRGARAQA---EYRSYVARVCLGDTN--------LYS 275
S Y VG+F D YF FR R + + + VARVC GD +
Sbjct: 218 SAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTT 277
Query: 276 YVEVPLAC------------QGQGLIQAAFLAPGTLLGVFAAGPRGTQ-AALCAFPMVEL 322
+++ LAC Q +Q T GVF A +A+C + + E+
Sbjct: 278 FLKARLACSAPNWQLYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEI 337
Query: 323 GASMEQARRLCYTAGGRG-------PSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHT 375
E + + + PS + + T L+ P++ +
Sbjct: 338 QRVFEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKH 397
Query: 376 PSPIAGRQPLEVQPLL-KLGQPVSAVAALQADG-----HMIAFLGDTQGQLYKVFLHGSQ 429
P P +PLL K G + + A + G + + F+G G L K G
Sbjct: 398 PLMEEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPW 457
Query: 430 GQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDP 489
+ Q+ S L+L S L+ + Q+ ++PVA C ++ CA C+ A+DP
Sbjct: 458 VHLIEELQLFDQEPMRS--LVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDP 515
Query: 490 LCGWCVLQGRCTRKGQCGRAGQL 512
C W V RC G G +G L
Sbjct: 516 YCAWSVNTSRCVAVG--GHSGSL 536
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 57.8 bits (138), Expect = 1e-07
Identities = 82/351 (23%), Positives = 140/351 (39%), Gaps = 53/351 (15%)
Query: 199 GVPPLAIRQLAGSQP-FSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARA-- 255
G P+ +R L GSQP ++ R + ++ S+V A + YF F +
Sbjct: 203 GSEPILMRTL-GSQPVLKTDNFLRWL-----HHDASFVAAIPSTQVVYFFFEETASEFDF 256
Query: 256 -QAEYRSYVARVCLGDTN--------LYSYVEVPLACQGQG-----LIQAAFLAPGT--- 298
+ + S VARVC D ++++ L C G +I+ A L P
Sbjct: 257 FERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQLPFNVIRHAVLLPADSPT 316
Query: 299 ---LLGVFAAGPR--GTQA-ALCAFPMVEL-----GASMEQARRLCYTAGGRGP-SGAEE 346
+ VF + + GT++ A+CAF ++++ G E + RGP +
Sbjct: 317 APHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRP 376
Query: 347 ATVEYGVTS-RCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPVSAVAALQA 405
+ G +S + +T D + ++ +P+ + +E L V L
Sbjct: 377 GSCSVGPSSDKALTFMKDH---FLMDEQVVGTPLLVKSGVEYTRLA-----VETAQGLDG 428
Query: 406 DGHMIAFLGDTQGQLYKVFLHG-SQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAH 464
H++ +LG T G L+K + G S + Q+ P + L + G+ ++V +
Sbjct: 429 HSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGA-VFVGFSG 487
Query: 465 QVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQW 515
V R+P A C + C C+ A+DP C W C A LN W
Sbjct: 488 GVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLS----APNLNSW 534
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 54.7 bits (130), Expect = 9e-07
Identities = 114/516 (22%), Positives = 184/516 (35%), Gaps = 112/516 (21%)
Query: 47 FSAPNTT-LNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVI-DSPDCVPFRDP 104
F A N + L PG+ L VGA N LF+L QLE +++ V + +
Sbjct: 50 FRAKNAVDFSQLTFDPGQKELVVGARNYLFRL----QLEDLSLIQAVEWECDEATKKACY 105
Query: 105 AECPQAQLTDNANQLLLVSSRAQELVACG-QVRQGVCETRRLGDVAEVLYQAE------- 156
++ + N ++LLV L CG VC R L ++ E+ Q
Sbjct: 106 SKGKSKEECQNYIRVLLVGG--DRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPY 163
Query: 157 DPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAGV-PPLAIRQLAGSQPFS 215
P G + PGRD + S G+ PPL Q ++
Sbjct: 164 SPQHNSTALLTAGGELYAATAMDFPGRDPAIYR-------SLGILPPLRTAQ------YN 210
Query: 216 SEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARAQAEYR--SYVARVCLGDTN- 272
S+ L ++V ++ YF FR S ARVC D
Sbjct: 211 SKWLNE----------PNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGG 260
Query: 273 -------LYSYVEVPLACQGQGLI-------QAAFLAP--GTLLGVFAAGPRGTQA-ALC 315
++++ L C G + Q+ F P + G+F A A+C
Sbjct: 261 RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVC 320
Query: 316 AFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPES-YPCG--D 372
F + + + GP +Y SR LP +P + CG D
Sbjct: 321 VFNLSAIAQAFS------------GP-------FKYQENSRSAWLPYPNPNPHFQCGTVD 361
Query: 373 EHTPSPIAGRQPLEVQPLL---KLGQPVSAVAALQADGHMIAFLGD--TQGQ---LYKVF 424
+ + R + Q + ++ QPV+ V + D + + QG+ ++ ++
Sbjct: 362 QGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHIIY 421
Query: 425 LHGSQGQVYHSQQVGPPGSAISPDLLLDS-------------------SGSHLYVLTAHQ 465
L G + ++V P + S LL+ S S L+V
Sbjct: 422 LATDYGTI---KKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREH 478
Query: 466 VDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCT 501
V +IP+ C + ++C+ AQDP CGW V+ +CT
Sbjct: 479 VVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCT 514
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 53.9 bits (128), Expect = 1e-06
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 410 IAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRI 469
+ FLG G+L+K G + + Q+ G + +LLLD+ LY + V ++
Sbjct: 463 VLFLGTGDGRLHKAVSVGPRVHIIEELQIFSSGQPVQ-NLLLDTHRGLLYAASHSGVVQV 521
Query: 470 PVAACPQFPDCASCLQAQDPLCGW 493
P+A C + C CL A+DP C W
Sbjct: 522 PMANCSLYRSCGDCLLARDPYCAW 545
Score = 33.9 bits (76), Expect = 1.6
Identities = 33/77 (42%), Positives = 36/77 (46%), Gaps = 17/77 (22%)
Query: 21 RWPPFGLCLLLLLLSPPP----------LPLTGAH----RFSAPNTTLNHLALAPGRG-- 64
R P L LLLLLL PPP LPL RF A + + N+ AL R
Sbjct: 22 RPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHIS-NYTALLLSRDGR 80
Query: 65 TLYVGAVNRLFQLSPEL 81
TLYVGA LF LS L
Sbjct: 81 TLYVGAREALFALSSNL 97
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 53.9 bits (128), Expect = 1e-06
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 410 IAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRI 469
+ FLG G+L+K G + + Q+ G + +LLLD+ LY + V ++
Sbjct: 463 VLFLGTGDGRLHKAVSVGPRVHIIEELQIFSSGQPVQ-NLLLDTHRGLLYAASHSGVVQV 521
Query: 470 PVAACPQFPDCASCLQAQDPLCGW 493
P+A C + C CL A+DP C W
Sbjct: 522 PMANCSLYRSCGDCLLARDPYCAW 545
Score = 33.9 bits (76), Expect = 1.6
Identities = 33/77 (42%), Positives = 36/77 (46%), Gaps = 17/77 (22%)
Query: 21 RWPPFGLCLLLLLLSPPP----------LPLTGAH----RFSAPNTTLNHLALAPGRG-- 64
R P L LLLLLL PPP LPL RF A + + N+ AL R
Sbjct: 22 RPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHIS-NYTALLLSRDGR 80
Query: 65 TLYVGAVNRLFQLSPEL 81
TLYVGA LF LS L
Sbjct: 81 TLYVGAREALFALSSNL 97
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 52.4 bits (124), Expect = 4e-06
Identities = 68/288 (23%), Positives = 107/288 (37%), Gaps = 57/288 (19%)
Query: 261 SYVARVCLGDTN---------LYSYVEVPLACQGQGLIQAAFLAPGTLLGVFAAGPRGTQ 311
S VARVC D S+++ L C G F + GV + G R
Sbjct: 261 SRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPVV 320
Query: 312 -------------AALCAFPMVELGASME------QARRLCYTAGGRG------PSGAEE 346
+A+CAF + ++ A E ++ +T P
Sbjct: 321 LAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAA 380
Query: 347 ATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLK--LGQPVSAVAALQ 404
++Y +S L+ +++P DE PS G P ++ L++ L + V A
Sbjct: 381 PGMQYNASSALPDDILNFVKTHPLMDEAVPS--LGHAPWILRTLMRHQLTRVAVDVGAGP 438
Query: 405 ADGHMIAFLGDTQGQLYKVFLH------GSQG--------QVYHSQQVGPPGSAISPDLL 450
+ FLG G + K + G+ G + Y + G PG + L
Sbjct: 439 WGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGETGQRL 498
Query: 451 L----DSSGSHLYVLTAHQVDRIPVAACPQFPDCA-SCLQAQDPLCGW 493
L D++ L V R+PVA C Q+ C +C+ +QDP CGW
Sbjct: 499 LSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGW 546
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 51.6 bits (122), Expect = 7e-06
Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 394 GQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDS 453
G PV+ A D + FLG G ++K + GS + QV ++ +L++
Sbjct: 432 GTPVTTPAGPTYD---LLFLGTADGWIHKAVVLGSGMHIIEETQVFRESQSVE-NLVISL 487
Query: 454 SGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGW 493
LYV V ++P+++C ++ C C+ A+DP CGW
Sbjct: 488 LQHSLYVGAPSGVIQLPLSSCSRYRSCYDCILARDPYCGW 527
>gi|126116589 fibrocystin L [Homo sapiens]
Length = 4243
Score = 51.2 bits (121), Expect = 9e-06
Identities = 91/402 (22%), Positives = 140/402 (34%), Gaps = 51/402 (12%)
Query: 849 GGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRV 908
G + + I G LG D+ AV + ++ ++ I + +P P G V V
Sbjct: 1761 GSVKVLIEGEGLGTVLEDI--AVFIGNQQFR---AIEVNENNITALVTPLPVGHHS-VSV 1814
Query: 909 AIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCP 968
+ S+ G++ + T P + SLSP G GGT L I G GNT+ +G +PC
Sbjct: 1815 VVGSK--GLALGNLTVSSPPVASLSPTSGSIGGGTTLVITGNGFYP-GNTTVTIGDEPCQ 1871
Query: 969 ILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRG 1028
I+ + P + CRT P G V + L + P L PS G
Sbjct: 1872 IIS-INPNEVYCRT-PAGTTGMVDVKIFVNTIAYPPLLFTYALEDTPFLRGIIPSRGPPG 1929
Query: 1029 GGRLIRVRGTGLDVVQRPLL------SVWLEADAEVQ---ASRAQPQDPQPRRSCGAPAA 1079
I G ++++ ++ +V + D+ VQ A P +A
Sbjct: 1930 TEIEITGSNFGFEILEISVMINNIQCNVTMANDSVVQCIVGDHAGGTFPVMMHHKTKGSA 1989
Query: 1080 DPQACIQ--------------LGGGLLQCSTVCSVN--SSSLLLCRSPAVPDRAHPQRVF 1123
+ GGG T N +S +L+C S DR
Sbjct: 1990 MSTVVFEYPLNIQNINPSQGSFGGGQTMTVTGTGFNPQNSIILVCGSECAIDRLRSDYTT 2049
Query: 1124 FTLD--------NVQVDFASASGGQGFLYQPNP-----RLAPLSREGPARPYRLKPGHVL 1170
+ Q S G+ P L PL + G L
Sbjct: 2050 LLCEIPSNNGTGAEQACEVSVVNGKDLSQSMTPFTYAVSLTPLITAVSPKRGSTAGGTRL 2109
Query: 1171 DVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAH 1212
V G G + + E+V + I +C V+ +TH+ C AH
Sbjct: 2110 TVVGSGFSENM--EDVHITIAEAKCDVEYSNKTHIICMTDAH 2149
Score = 45.8 bits (107), Expect = 4e-04
Identities = 60/249 (24%), Positives = 99/249 (39%), Gaps = 20/249 (8%)
Query: 819 YGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPC 878
Y PL A+E P + + P GPP G + I GSN G F ++ +V + + C
Sbjct: 1903 YPPLLFTYALE---DTPFLRGIIPSRGPP--GTEIEITGSNFG--FEILEISVMINNIQC 1955
Query: 879 NPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPPGISSQHFTYQDPV-LLSLSPRWG 937
N + + + C+ GT PV + K++ +S+ F Y P+ + +++P G
Sbjct: 1956 NVTMA---NDSVVQCIVGDHAGGTF-PVMMHHKTKGSAMSTVVFEY--PLNIQNINPSQG 2009
Query: 938 PQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCP-EAIVCRTRPQAAPG--EAAVL 994
GG +T+ G N+ V G C I ++C G +A +
Sbjct: 2010 SFGGGQTMTVTGTGFNPQ-NSIILVCGSECAIDRLRSDYTTLLCEIPSNNGTGAEQACEV 2068
Query: 995 VVFGHAQRTLLASPFRYTAN--PQLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWL 1052
V + +PF Y + P + A P GG + V G+G +
Sbjct: 2069 SVVNGKDLSQSMTPFTYAVSLTPLITAVSPKRGSTAGGTRLTVVGSGFSENMEDVHITIA 2128
Query: 1053 EADAEVQAS 1061
EA +V+ S
Sbjct: 2129 EAKCDVEYS 2137
Score = 44.7 bits (104), Expect = 9e-04
Identities = 50/175 (28%), Positives = 70/175 (40%), Gaps = 20/175 (11%)
Query: 835 PSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCV 894
P + A+ P G E G LTI+GS + A VSV C+ L + C
Sbjct: 1067 PLVLAISPSQGSYEEGTILTIVGSGFSPSSA---VTVSVGPVGCS---LLSVDEKELKC- 1119
Query: 895 TSPAPNGTTGPVRVAIKSQPPGISSQ------HFTYQDPVLLSLSPRWGPQAGGTQLTIR 948
NG+ G VA+ G++ +F YQ + + P G AGGT LT+
Sbjct: 1120 --QILNGSAGHAPVAVSMADVGLAQNVGGEEFYFVYQSQI-SHIWPDSGSIAGGTLLTLS 1176
Query: 949 GQHLQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRT 1003
G N+ VG + C ++E I CRT P+ G + V Q T
Sbjct: 1177 G--FGFNENSKVLVGNETCNVIEGDL-NRITCRT-PKKTEGTVDISVTTNGFQAT 1227
Score = 43.5 bits (101), Expect = 0.002
Identities = 57/217 (26%), Positives = 89/217 (41%), Gaps = 25/217 (11%)
Query: 837 IDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTS 896
I + P +G GG LT+ G V V + CN + RI C T
Sbjct: 1157 ISHIWPDSGSIAGGTLLTLSGFGFNE-----NSKVLVGNETCNV---IEGDLNRITCRT- 1207
Query: 897 PAPNGTTGPVRVAIKSQP-PGISSQHFTY---QDPVLLSLSPRWGPQAGGTQLTIRGQHL 952
P T G V +++ + + F+Y Q P++ SP+ G LTI+G +
Sbjct: 1208 --PKKTEGTVDISVTTNGFQATARDAFSYNCLQTPIITDFSPKVRTILGEVNLTIKGYNF 1265
Query: 953 --QTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVV---FGHAQ-RTLLA 1006
+ N + +VGG+ C IL + I C P+ +PG+ + V +G A R L
Sbjct: 1266 GNELTQNMAVYVGGKTCQILHWNFTD-IRC-LLPKLSPGKHDIYVEVRNWGFASTRDKLN 1323
Query: 1007 SPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVV 1043
S +Y ++ + P GG I +RG G +
Sbjct: 1324 SSIQYVL--EVTSMFPQRGSLFGGTEITIRGFGFSTI 1358
Score = 42.7 bits (99), Expect = 0.003
Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 12/121 (9%)
Query: 835 PSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCV 894
P I AV P G GG LT++GS DV +++A C+ E Y I+C+
Sbjct: 2091 PLITAVSPKRGSTAGGTRLTVVGSGFSENMEDVH--ITIAEAKCDVE---YSNKTHIICM 2145
Query: 895 TSPAPNGTTGPVRVAIKSQPPG-ISSQHFTYQDPVLLSLSPRWG----PQAGGTQLTIRG 949
T PV V I+ + + F Y D + S WG P+ G + +G
Sbjct: 2146 TDAHTLSGWAPVCVHIRGVGMAKLDNADFLYVDAWSSNFS--WGGKSPPEEGSLVVITKG 2203
Query: 950 Q 950
Q
Sbjct: 2204 Q 2204
Score = 38.1 bits (87), Expect = 0.083
Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Query: 934 PRWGPQAGGTQLTIRGQHL-QTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQ 985
P G GGT LTI G+ QT VGG+PC IL V +I C+T P+
Sbjct: 277 PSQGSIRGGTTLTISGRFFDQTDFPVRVLVGGEPCDILN-VTENSICCKTPPK 328
Score = 33.1 bits (74), Expect = 2.7
Identities = 30/117 (25%), Positives = 48/117 (41%), Gaps = 4/117 (3%)
Query: 927 PVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQA 986
P++L++SP G GT LTI G + VG C +L V + + C+ +
Sbjct: 1067 PLVLAISPSQGSYEEGTILTIVGSGFSPSSAVTVSVGPVGCSLLS-VDEKELKCQILNGS 1125
Query: 987 APGEAAVLVVFGHA--QRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLD 1041
A G A V V + + F + Q+ P + GG L+ + G G +
Sbjct: 1126 A-GHAPVAVSMADVGLAQNVGGEEFYFVYQSQISHIWPDSGSIAGGTLLTLSGFGFN 1181
Score = 32.3 bits (72), Expect = 4.5
Identities = 44/177 (24%), Positives = 65/177 (36%), Gaps = 43/177 (24%)
Query: 835 PSIDAVEPLTGPPEGGLALTILGSNLGRAFA------------DVQYAVSVASRPCNPEP 882
P + + P G G LTI G +A VQ S S C+ E
Sbjct: 31 PKVTEIIPKYGSINGATRLTIRGEGFSQANQFNYGVDNAELGNSVQLISSFQSITCDVEK 90
Query: 883 SLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPPG--------ISSQHFTY-----QDPVL 929
S +I C T P + VRV++ P I+S T+ + P +
Sbjct: 91 DASH-STQITCYTRAMPEDSY-TVRVSVDGVPVTENNTCKGHINSWECTFNAKSFRTPTI 148
Query: 930 LSLSPRWGPQAGGTQLTIRGQ----------HLQTGGNT----SAFVGGQPCPILEP 972
S++P G GT +TI+G+ L + G ++GG PC +L P
Sbjct: 149 RSITPLSGTP--GTLITIQGRIFTDVYGSNIALSSNGKNVRILRVYIGGMPCELLIP 203
>gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic
domain, (semaphorin) 6A [Homo sapiens]
Length = 1030
Score = 48.5 bits (114), Expect = 6e-05
Identities = 40/151 (26%), Positives = 65/151 (43%), Gaps = 15/151 (9%)
Query: 366 ESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKV-- 423
+++P DE PS L +L + AA H + FLG +G + K
Sbjct: 393 KTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLA 452
Query: 424 ------FLHGS----QGQVYHSQQVGPPGSAISP--DLLLDSSGSHLYVLTAHQVDRIPV 471
FL+ S + VY+S++ G + LD + S LYV + V ++P+
Sbjct: 453 RIGNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPL 512
Query: 472 AACPQFPDCA-SCLQAQDPLCGWCVLQGRCT 501
C + C +C+ ++DP CGW G C+
Sbjct: 513 GRCERHGKCKKTCIASRDPYCGWIKEGGACS 543
>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
Length = 666
Score = 47.4 bits (111), Expect = 1e-04
Identities = 44/163 (26%), Positives = 72/163 (44%), Gaps = 26/163 (15%)
Query: 362 LDSPESYPCGDEHTPSP-----IAGRQP---LEVQPLLKLGQPVS---------AVAALQ 404
L +P C + P P +A R P V+P+ L P+ AV +Q
Sbjct: 358 LPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQ 417
Query: 405 A---DGHMIAFLGDTQGQLYKVFLHGSQGQ--VYHSQQVGP-PGSAISPDLLLDSSGSHL 458
A + + +L +G ++KV G Q ++ ++ P +A + LD+ L
Sbjct: 418 ASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKL 477
Query: 459 YVLTAHQVDRIPVAACPQFPD-CASCLQAQDPLCGWCVLQGRC 500
YV + +V ++P+ C + C CL ++DP CGW QGRC
Sbjct: 478 YVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWD--QGRC 518
>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
Length = 501
Score = 47.4 bits (111), Expect = 1e-04
Identities = 44/163 (26%), Positives = 72/163 (44%), Gaps = 26/163 (15%)
Query: 362 LDSPESYPCGDEHTPSP-----IAGRQP---LEVQPLLKLGQPVS---------AVAALQ 404
L +P C + P P +A R P V+P+ L P+ AV +Q
Sbjct: 193 LPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQ 252
Query: 405 A---DGHMIAFLGDTQGQLYKVFLHGSQGQ--VYHSQQVGP-PGSAISPDLLLDSSGSHL 458
A + + +L +G ++KV G Q ++ ++ P +A + LD+ L
Sbjct: 253 ASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKL 312
Query: 459 YVLTAHQVDRIPVAACPQFPD-CASCLQAQDPLCGWCVLQGRC 500
YV + +V ++P+ C + C CL ++DP CGW QGRC
Sbjct: 313 YVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWD--QGRC 353
>gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]
Length = 652
Score = 47.4 bits (111), Expect = 1e-04
Identities = 44/163 (26%), Positives = 72/163 (44%), Gaps = 26/163 (15%)
Query: 362 LDSPESYPCGDEHTPSP-----IAGRQP---LEVQPLLKLGQPVS---------AVAALQ 404
L +P C + P P +A R P V+P+ L P+ AV +Q
Sbjct: 344 LPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQ 403
Query: 405 A---DGHMIAFLGDTQGQLYKVFLHGSQGQ--VYHSQQVGP-PGSAISPDLLLDSSGSHL 458
A + + +L +G ++KV G Q ++ ++ P +A + LD+ L
Sbjct: 404 ASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKL 463
Query: 459 YVLTAHQVDRIPVAACPQFPD-CASCLQAQDPLCGWCVLQGRC 500
YV + +V ++P+ C + C CL ++DP CGW QGRC
Sbjct: 464 YVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWD--QGRC 504
>gi|19923279 semaphorin W [Homo sapiens]
Length = 770
Score = 45.8 bits (107), Expect = 4e-04
Identities = 124/559 (22%), Positives = 191/559 (34%), Gaps = 120/559 (21%)
Query: 24 PFGLCLLLLLLSP-----------PPLPLTGAH----RFSAPNT-TLNHLALAPGRGTLY 67
PF L LL +L P LP++ A RF+ P+T + L + P TLY
Sbjct: 19 PFPLLLLAVLSGPVSGRVPRSVPRTSLPISEADSCLTRFAVPHTYNYSVLLVDPASHTLY 78
Query: 68 VGAVNRLFQLSPELQLEA---VAVTGPVIDSPDC-VPFRDPAECPQAQLTDNANQLLLVS 123
VGA + +F LS E + P +C + EC N Q+L ++
Sbjct: 79 VGARDTIFALSLPFSGERPRRIDWMVPEAHRQNCRKKGKKEDEC------HNFVQILAIA 132
Query: 124 SRAQELVACGQV----RQGVCETRRLGDVAEVLYQAEDPGDGQ--FVAANTPGVATVGLV 177
+ A L+ CG + GV + R V + + G G+ F A G
Sbjct: 133 N-ASHLLTCGTFAFDPKCGVIDVSRFQQVERL-----ESGRGKCPFEPAQRSAAVMAG-- 184
Query: 178 VPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDFSDYNNSYVGA 237
G L A ++ G++P + +GR +D S++ A
Sbjct: 185 ----------------GVLYAAT----VKNYLGTEPIITRAVGRAEDWIRTDTLPSWLNA 224
Query: 238 FA---------------DARSAYFVFRRRGARAQAEYRSY----VARVCLGDTN------ 272
A D + F +RA Y VARVC GD
Sbjct: 225 PAFVAAVALSPAEWGDEDGDDEIYFFFTETSRAFDSYERIKVPRVARVCAGDLGGRKTLQ 284
Query: 273 --LYSYVEVPLACQGQG-------LIQAAFLAP----GTLL--GVFAAGPRG-TQAALCA 316
++++ L C G L A L P GT + G+F++ G T +A+CA
Sbjct: 285 QRWTTFLKADLLCPGPEHGRASSVLQDVAVLRPELGAGTPIFYGIFSSQWEGATISAVCA 344
Query: 317 FPMVELGASMEQARRLCYTAGGRG--------PSGAEEATVEYGVTSRCVTLPLDSPE-- 366
F ++ + R RG P + + R L P+
Sbjct: 345 FRPQDIRTVLNGPFRELKHDCNRGLPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRV 404
Query: 367 -----SYPCGDEHTPSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLY 421
+P D P G L L V +L + + +LG G L+
Sbjct: 405 LTFIRDHPLMDRPV-FPADGHPLLVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLH 463
Query: 422 KVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCA 481
+ G+Q V + P + L S L V + +V ++ C + C+
Sbjct: 464 RAVRIGAQLSVLEDLALFPEPQPVENMKLYHS---WLLVGSRTEVTQVNTTNCGRLQSCS 520
Query: 482 SCLQAQDPLCGWCVLQGRC 500
C+ AQDP+C W C
Sbjct: 521 ECILAQDPVCAWSFRLDEC 539
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,463,507
Number of Sequences: 37866
Number of extensions: 4377888
Number of successful extensions: 12037
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 11578
Number of HSP's gapped (non-prelim): 230
length of query: 1909
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1792
effective length of database: 13,817,196
effective search space: 24760415232
effective search space used: 24760415232
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.