Guide to the Human Genome
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Search of human proteins with 28872722

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28872722 B-cell translocation gene 3 isoform b [Homo
sapiens]
         (252 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28872722 B-cell translocation gene 3 isoform b [Homo sapiens]      541   e-154
gi|195963406 B-cell translocation gene 3 isoform a [Homo sapiens]     520   e-148
gi|8923958 B-cell translocation gene 4 [Homo sapiens]                 189   3e-48
gi|4502473 B-cell translocation protein 1 [Homo sapiens]               91   1e-18
gi|5802988 B-cell translocation gene 2 [Homo sapiens]                  88   6e-18
gi|5032187 transducer of ERBB2, 1 [Homo sapiens]                       87   1e-17
gi|7706739 transducer of ERBB2, 2 [Homo sapiens]                       83   3e-16
gi|120952764 mastermind-like domain containing 1 [Homo sapiens]        42   7e-04
gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo s...    35   0.062
gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo s...    35   0.062
gi|118402590 myosin XV [Homo sapiens]                                  35   0.081
gi|46370073 GRB2-associated binding protein 1 isoform b [Homo sa...    35   0.081
gi|46370071 GRB2-associated binding protein 1 isoform a [Homo sa...    35   0.081
gi|55741677 SET domain containing 1A [Homo sapiens]                    35   0.081
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         34   0.11 
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         33   0.18 
gi|134254450 patched isoform S [Homo sapiens]                          33   0.24 
gi|134254435 patched isoform S [Homo sapiens]                          33   0.24 
gi|134254468 patched isoform S [Homo sapiens]                          33   0.24 
gi|134254452 patched isoform S [Homo sapiens]                          33   0.24 
gi|134254432 patched isoform L' [Homo sapiens]                         33   0.24 
gi|134254466 patched isoform M [Homo sapiens]                          33   0.24 
gi|134254446 patched isoform L [Homo sapiens]                          33   0.24 
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    32   0.53 
gi|190194381 phospholipid scramblase 4 isoform b [Homo sapiens]        32   0.53 
gi|190341019 phospholipid scramblase 4 isoform a [Homo sapiens]        32   0.53 
gi|190194379 phospholipid scramblase 4 isoform a [Homo sapiens]        32   0.53 
gi|190194377 phospholipid scramblase 4 isoform a [Homo sapiens]        32   0.53 
gi|210032580 SET domain containing 1B [Homo sapiens]                   32   0.53 
gi|170932516 paxillin isoform 2 [Homo sapiens]                         32   0.69 

>gi|28872722 B-cell translocation gene 3 isoform b [Homo sapiens]
          Length = 252

 Score =  541 bits (1393), Expect = e-154
 Identities = 252/252 (100%), Positives = 252/252 (100%)

Query: 1   MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI 60
           MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI
Sbjct: 1   MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI 60

Query: 61  RVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCRYGEKNNAFIVASFENK 120
           RVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCRYGEKNNAFIVASFENK
Sbjct: 61  RVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCRYGEKNNAFIVASFENK 120

Query: 121 DENKDEISRKVTRALDKVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFP 180
           DENKDEISRKVTRALDKVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFP
Sbjct: 121 DENKDEISRKVTRALDKVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFP 180

Query: 181 PLPMWHPLPRKKPGMYRGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPPPGMHCDR 240
           PLPMWHPLPRKKPGMYRGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPPPGMHCDR
Sbjct: 181 PLPMWHPLPRKKPGMYRGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPPPGMHCDR 240

Query: 241 NHWINPHMLAPH 252
           NHWINPHMLAPH
Sbjct: 241 NHWINPHMLAPH 252


>gi|195963406 B-cell translocation gene 3 isoform a [Homo sapiens]
          Length = 296

 Score =  520 bits (1338), Expect = e-148
 Identities = 252/296 (85%), Positives = 252/296 (85%), Gaps = 44/296 (14%)

Query: 1   MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI 60
           MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI
Sbjct: 1   MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI 60

Query: 61  RVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCR---------------- 104
           RVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCR                
Sbjct: 61  RVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCRRDGVSPCWPDCSQTPD 120

Query: 105 ----------------------------YGEKNNAFIVASFENKDENKDEISRKVTRALD 136
                                       YGEKNNAFIVASFENKDENKDEISRKVTRALD
Sbjct: 121 LVIRPPWPPKALDYRREPLRPASSFLIMYGEKNNAFIVASFENKDENKDEISRKVTRALD 180

Query: 137 KVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMY 196
           KVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMY
Sbjct: 181 KVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMY 240

Query: 197 RGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPPPGMHCDRNHWINPHMLAPH 252
           RGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPPPGMHCDRNHWINPHMLAPH
Sbjct: 241 RGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPPPGMHCDRNHWINPHMLAPH 296


>gi|8923958 B-cell translocation gene 4 [Homo sapiens]
          Length = 223

 Score =  189 bits (479), Expect = 3e-48
 Identities = 96/192 (50%), Positives = 132/192 (68%), Gaps = 4/192 (2%)

Query: 1   MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI 60
           M++EIA  VFF TRLV+KHDKL K+ +E FAEKL  IL E Y++HW+ + PSKGQA+RCI
Sbjct: 1   MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCI 60

Query: 61  RVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCRYGEKNNAFIVASFENK 120
           R+N  Q  DP + +AC  S + +S LGLPKE+T+WVDP EVCCRYGEKN+ F VASF+ +
Sbjct: 61  RINNNQNKDPILERACVESNVDFSHLGLPKEMTIWVDPFEVCCRYGEKNHPFTVASFKGR 120

Query: 121 DENKDEISRKVTRALDKVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFP 180
            E + E+ ++++ A+ + +SD  SG+S  +E  SKE  V P    +    +YQ+ E +  
Sbjct: 121 WE-EWELYQQISYAVSRASSDVSSGTSCDEESCSKEPRVIPK--VSNPKSIYQV-ENLKQ 176

Query: 181 PLPMWHPLPRKK 192
           P   W  +PRKK
Sbjct: 177 PFQSWLQIPRKK 188


>gi|4502473 B-cell translocation protein 1 [Homo sapiens]
          Length = 171

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 47/116 (40%), Positives = 69/116 (59%), Gaps = 4/116 (3%)

Query: 1   MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI 60
           M  EIAA V F ++ +R      +  ++ F++ L  +L E YK+HW+PEKP KG  YRCI
Sbjct: 11  MIGEIAAAVSFISKFLRTKGLTSERQLQTFSQSLQELLAEHYKHHWFPEKPCKGSGYRCI 70

Query: 61  RVNKFQRVDPDVLKACENSCILYSDLG--LPKELTLWVDPCEVCCRYGEKNNAFIV 114
           R+N   ++DP + +A +   +   +L   LP ELTLWVDP EV  R GE  +  ++
Sbjct: 71  RIN--HKMDPLIGQAAQRIGLSSQELFRLLPSELTLWVDPYEVSYRIGEDGSICVL 124


>gi|5802988 B-cell translocation gene 2 [Homo sapiens]
          Length = 158

 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 48/116 (41%), Positives = 67/116 (57%), Gaps = 4/116 (3%)

Query: 1   MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI 60
           M  EIAA V F + L+R    + ++ ++ F+  L   L E YK+HW+PEKPSKG  YRCI
Sbjct: 9   MLPEIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPSKGSGYRCI 68

Query: 61  RVNKFQRVDPDVLKACENSCILYSDLG--LPKELTLWVDPCEVCCRYGEKNNAFIV 114
           R+N   ++DP + +      +    L   LP ELTLWVDP EV  R GE  +  ++
Sbjct: 69  RIN--HKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSICVL 122


>gi|5032187 transducer of ERBB2, 1 [Homo sapiens]
          Length = 345

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 49/156 (31%), Positives = 87/156 (55%), Gaps = 7/156 (4%)

Query: 19  HDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCIRVNKFQRVDPDVLKACEN 78
           ++KL +  V  F E+L  +L++KY+ HWYPEKP KG  +RCI +   ++VDP + +A + 
Sbjct: 17  YNKLPRRRVNIFGEELERLLKKKYEGHWYPEKPYKGSGFRCIHIG--EKVDPVIEQASKE 74

Query: 79  SCILYSDL--GLPKELTLWVDPCEVCCRYGEKNNAFIVASFENKDENKDEISRKVTRALD 136
           S +   D+   LP++L++W+DP EV  + GEK    ++   +N +EN  E+ +++  + +
Sbjct: 75  SGLDIDDVRGNLPQDLSVWIDPFEVSYQIGEKGPVKVLYVDDN-NENGCELDKEIKNSFN 133

Query: 137 KVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVY 172
                +   S  +   +S      P   +AA SP +
Sbjct: 134 PEAQVFMPISDPASSVSSSPS--PPFGHSAAVSPTF 167


>gi|7706739 transducer of ERBB2, 2 [Homo sapiens]
          Length = 344

 Score = 82.8 bits (203), Expect = 3e-16
 Identities = 45/160 (28%), Positives = 83/160 (51%), Gaps = 9/160 (5%)

Query: 19  HDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCIRVNKFQRVDPDVLKACEN 78
           ++KL +   + F E+L  +L++KY+ HWYPEKP KG  +RC+ +   + VDP V  A + 
Sbjct: 17  YNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHIG--EMVDPVVELAAKR 74

Query: 79  SCILYSDL--GLPKELTLWVDPCEVCCRYGEKNNAFIVASFENKDENKDEISRKVTRALD 136
           S +   D+   +P+EL++W+DP EV  + GEK    ++   +++     E+ +++  + +
Sbjct: 75  SGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVKVLYLDDSEGCGAPELDKEIKSSFN 134

Query: 137 K-----VTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPV 171
                 V       S S+    S      P+ +  +A P+
Sbjct: 135 PDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPI 174


>gi|120952764 mastermind-like domain containing 1 [Homo sapiens]
          Length = 774

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 5/94 (5%)

Query: 144 SGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFPPLPM--WHPLPRKK--PGMYRGN 199
           +G S S   TSK++    SS+  + S V  +  +  PPLP+  WH   + K      +G+
Sbjct: 258 TGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQWHHAHQLKALAASKQGS 317

Query: 200 GHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPP 233
             +   P P   G P  G  + PYRP+P    PP
Sbjct: 318 ATKQQGPTPSWSGLPPPG-LSPPYRPVPSPHPPP 350


>gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo
           sapiens]
          Length = 634

 Score = 35.0 bits (79), Expect = 0.062
 Identities = 34/131 (25%), Positives = 50/131 (38%), Gaps = 21/131 (16%)

Query: 113 IVASFENKDENKDEISRKVTRALDKVTSDYHSGSSSS-----DEETSKEMEVKPSSVTAA 167
           +  +FEN + +   I  + TR  + V S+  +GS S      +E+   + E   +     
Sbjct: 91  VTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETP 150

Query: 168 ASPVYQISELIFPPLPMWHPLPRKKP----GMYRGNGHQNHYPPPVPFGYPNQGRKNKPY 223
           A+P    S    PP P   P P+K P    G   G  H+    PP+         K    
Sbjct: 151 AAPALPPSA---PPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPI---------KKNTK 198

Query: 224 RPIPVTWVPPP 234
            P     VPPP
Sbjct: 199 APGKQAPVPPP 209


>gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo
           sapiens]
          Length = 645

 Score = 35.0 bits (79), Expect = 0.062
 Identities = 34/131 (25%), Positives = 50/131 (38%), Gaps = 21/131 (16%)

Query: 113 IVASFENKDENKDEISRKVTRALDKVTSDYHSGSSSS-----DEETSKEMEVKPSSVTAA 167
           +  +FEN + +   I  + TR  + V S+  +GS S      +E+   + E   +     
Sbjct: 102 VTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETP 161

Query: 168 ASPVYQISELIFPPLPMWHPLPRKKP----GMYRGNGHQNHYPPPVPFGYPNQGRKNKPY 223
           A+P    S    PP P   P P+K P    G   G  H+    PP+         K    
Sbjct: 162 AAPALPPSA---PPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPI---------KKNTK 209

Query: 224 RPIPVTWVPPP 234
            P     VPPP
Sbjct: 210 APGKQAPVPPP 220


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 34.7 bits (78), Expect = 0.081
 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 7/56 (12%)

Query: 179 FPPLPMWHPLPRKKPGMYRGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPPP 234
           F P  + + +P  + G+Y G G +  YPP VP+ YP +      Y      WVPPP
Sbjct: 369 FDPYGVHYTVPYAE-GVY-GGGDEAIYPPEVPYFYPEESASAFVY-----PWVPPP 417


>gi|46370073 GRB2-associated binding protein 1 isoform b [Homo
           sapiens]
          Length = 694

 Score = 34.7 bits (78), Expect = 0.081
 Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 10/105 (9%)

Query: 137 KVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMY 196
           KV +    GS SS+E     + + P+S      P  Q S     P+   + +P   PG +
Sbjct: 428 KVKNVLTVGSVSSEELDENYVPMNPNS------PPRQHSSSFTEPIQEANYVPMT-PGTF 480

Query: 197 RGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPPPGMHCDRN 241
             +      PPP   G+     K  P RP+PV    PP +  DRN
Sbjct: 481 DFSSFGMQVPPPAHMGF-RSSPKTPPRRPVPVADCEPPPV--DRN 522


>gi|46370071 GRB2-associated binding protein 1 isoform a [Homo
           sapiens]
          Length = 724

 Score = 34.7 bits (78), Expect = 0.081
 Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 10/105 (9%)

Query: 137 KVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMY 196
           KV +    GS SS+E     + + P+S      P  Q S     P+   + +P   PG +
Sbjct: 428 KVKNVLTVGSVSSEELDENYVPMNPNS------PPRQHSSSFTEPIQEANYVPMT-PGTF 480

Query: 197 RGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPPPGMHCDRN 241
             +      PPP   G+     K  P RP+PV    PP +  DRN
Sbjct: 481 DFSSFGMQVPPPAHMGF-RSSPKTPPRRPVPVADCEPPPV--DRN 522


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 34.7 bits (78), Expect = 0.081
 Identities = 32/138 (23%), Positives = 55/138 (39%), Gaps = 23/138 (16%)

Query: 118  ENKDENKDEISRKVTRALDKVTSDYHSGSSSSDEETSK--EMEVKPSSVTAAASPVYQIS 175
            EN   +  E S   + +    +S   S SSSS E +S+  E E +P+++ +A+ P  ++ 
Sbjct: 1026 ENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVP 1085

Query: 176  ELIFPPLPMWHPLPRKKPGMYRGNGHQNHYPPPVPFGYPNQGRKNKPYRP---------- 225
              +  P P+  P+P +  G       +    P  P G   +   + P RP          
Sbjct: 1086 --VPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAP 1143

Query: 226  ---------IPVTWVPPP 234
                      P+  +PPP
Sbjct: 1144 APRPDERPSSPIPLLPPP 1161


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 18/69 (26%), Positives = 32/69 (46%)

Query: 117  FENKDENKDEISRKVTRALDKVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISE 176
            + N  E  +EIS + ++ +D++T         SD+E+S  +EV            + + E
Sbjct: 3471 YRNSIEFFEEISDEASKLVDRLTQSEREQEIVSDDESSSALEVSVIENLPPVETEHSVPE 3530

Query: 177  LIFPPLPMW 185
             IF   P+W
Sbjct: 3531 DIFDTRPIW 3539



 Score = 28.5 bits (62), Expect = 5.8
 Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 7/86 (8%)

Query: 140  SDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMYRGN 199
            ++ HS +SSS + T K   V PS+ T   SPV        PP+       ++ P    G 
Sbjct: 1863 TERHSPASSSSK-TEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDKRPPVSPSGR 1921

Query: 200  GHQNHYPPPVPFGYPNQGRKNKPYRP 225
              ++   PPV    P +  K  P  P
Sbjct: 1922 TEKH---PPVS---PGRTEKRLPVSP 1941


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 33.5 bits (75), Expect = 0.18
 Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 6/94 (6%)

Query: 144 SGSSSSDEETSKEMEVKPSSVTAAASP----VYQISELIFPPLPMWHPLPRKKPGMYRGN 199
           S   SS  +  + + V P     AA P    + +I E   PPLP  HP P +KP +    
Sbjct: 324 SPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKI-ETTHPPLPPAHPPPDRKPPLAAAL 382

Query: 200 GHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPP 233
           G +   P PV      + +   P  P PV   PP
Sbjct: 383 G-EAEPPGPVDATDLPKVQIPPPAHPAPVHQPPP 415


>gi|134254450 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 29/108 (26%)

Query: 143  HSGSSSSDEETSKEMEVKPSS--------------------VTAAASPVYQISELIFPPL 182
            HSGS SSD E S +  V   S                    V A  +PV+  S ++ P  
Sbjct: 1064 HSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPE- 1122

Query: 183  PMWHP--LPRKKPGMYRGN---GHQNHYPPPVPFGYPNQGRKNKPYRP 225
               HP   PR++P +  G+   G Q   P   P   P +G    PYRP
Sbjct: 1123 SRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDP---PREGLWPPPYRP 1167


>gi|134254435 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 29/108 (26%)

Query: 143  HSGSSSSDEETSKEMEVKPSS--------------------VTAAASPVYQISELIFPPL 182
            HSGS SSD E S +  V   S                    V A  +PV+  S ++ P  
Sbjct: 1064 HSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPE- 1122

Query: 183  PMWHP--LPRKKPGMYRGN---GHQNHYPPPVPFGYPNQGRKNKPYRP 225
               HP   PR++P +  G+   G Q   P   P   P +G    PYRP
Sbjct: 1123 SRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDP---PREGLWPPPYRP 1167


>gi|134254468 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 29/108 (26%)

Query: 143  HSGSSSSDEETSKEMEVKPSS--------------------VTAAASPVYQISELIFPPL 182
            HSGS SSD E S +  V   S                    V A  +PV+  S ++ P  
Sbjct: 1064 HSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPE- 1122

Query: 183  PMWHP--LPRKKPGMYRGN---GHQNHYPPPVPFGYPNQGRKNKPYRP 225
               HP   PR++P +  G+   G Q   P   P   P +G    PYRP
Sbjct: 1123 SRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDP---PREGLWPPPYRP 1167


>gi|134254452 patched isoform S [Homo sapiens]
          Length = 1296

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 29/108 (26%)

Query: 143  HSGSSSSDEETSKEMEVKPSS--------------------VTAAASPVYQISELIFPPL 182
            HSGS SSD E S +  V   S                    V A  +PV+  S ++ P  
Sbjct: 1064 HSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPE- 1122

Query: 183  PMWHP--LPRKKPGMYRGN---GHQNHYPPPVPFGYPNQGRKNKPYRP 225
               HP   PR++P +  G+   G Q   P   P   P +G    PYRP
Sbjct: 1123 SRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDP---PREGLWPPPYRP 1167


>gi|134254432 patched isoform L' [Homo sapiens]
          Length = 1446

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 29/108 (26%)

Query: 143  HSGSSSSDEETSKEMEVKPSS--------------------VTAAASPVYQISELIFPPL 182
            HSGS SSD E S +  V   S                    V A  +PV+  S ++ P  
Sbjct: 1214 HSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPE- 1272

Query: 183  PMWHP--LPRKKPGMYRGN---GHQNHYPPPVPFGYPNQGRKNKPYRP 225
               HP   PR++P +  G+   G Q   P   P   P +G    PYRP
Sbjct: 1273 SRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDP---PREGLWPPPYRP 1317


>gi|134254466 patched isoform M [Homo sapiens]
          Length = 1381

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 29/108 (26%)

Query: 143  HSGSSSSDEETSKEMEVKPSS--------------------VTAAASPVYQISELIFPPL 182
            HSGS SSD E S +  V   S                    V A  +PV+  S ++ P  
Sbjct: 1149 HSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPE- 1207

Query: 183  PMWHP--LPRKKPGMYRGN---GHQNHYPPPVPFGYPNQGRKNKPYRP 225
               HP   PR++P +  G+   G Q   P   P   P +G    PYRP
Sbjct: 1208 SRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDP---PREGLWPPPYRP 1252


>gi|134254446 patched isoform L [Homo sapiens]
          Length = 1447

 Score = 33.1 bits (74), Expect = 0.24
 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 29/108 (26%)

Query: 143  HSGSSSSDEETSKEMEVKPSS--------------------VTAAASPVYQISELIFPPL 182
            HSGS SSD E S +  V   S                    V A  +PV+  S ++ P  
Sbjct: 1215 HSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPE- 1273

Query: 183  PMWHP--LPRKKPGMYRGN---GHQNHYPPPVPFGYPNQGRKNKPYRP 225
               HP   PR++P +  G+   G Q   P   P   P +G    PYRP
Sbjct: 1274 SRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDP---PREGLWPPPYRP 1318


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 32.0 bits (71), Expect = 0.53
 Identities = 41/151 (27%), Positives = 60/151 (39%), Gaps = 28/151 (18%)

Query: 118  ENKDENKDEISRKVTRALDKVT----SDYHSGSSSSD-------EETSKEMEV------- 159
            E KD  +  + + V  +  K T     D     SSS+       EE S+E  V       
Sbjct: 1224 EKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPES 1283

Query: 160  KPSSVTAAASPVYQISE--LIFPPLPMWHPLPRKKPGMYRGNGHQNHYPPPVPFGYPNQG 217
            K ++  A+     Q+S+  L+ PP P     PRK+      +  +   PPP P   P Q 
Sbjct: 1284 KQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPP-PESGPEQS 1342

Query: 218  RKNK--PYRPIPVTWVP-----PPGMHCDRN 241
            ++ K  P   IPV   P     PP ++   N
Sbjct: 1343 KQKKVAPRPSIPVKQKPKEKEKPPPVNKQEN 1373


>gi|190194381 phospholipid scramblase 4 isoform b [Homo sapiens]
          Length = 239

 Score = 32.0 bits (71), Expect = 0.53
 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 20/102 (19%)

Query: 148 SSDEETSKEME--VKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMYRGNGHQNHY 205
           ++ E+ + EME   KP      A P Y    L  PP     P     P  Y G     +Y
Sbjct: 7   TAPEQPAGEMENQTKPPDPRPDAPPEYNSHFLPGPPGTAVPP-----PTGYPGGLPMGYY 61

Query: 206 PPPVPFGYP-------------NQGRKNKPYRPIPVTWVPPP 234
            P  P  +P               G+   P + +P+TW+P P
Sbjct: 62  SPQQPSTFPLYQPVGGIHPVRYQPGKYPMPNQSVPITWMPGP 103


>gi|190341019 phospholipid scramblase 4 isoform a [Homo sapiens]
          Length = 329

 Score = 32.0 bits (71), Expect = 0.53
 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 20/102 (19%)

Query: 148 SSDEETSKEME--VKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMYRGNGHQNHY 205
           ++ E+ + EME   KP      A P Y    L  PP     P     P  Y G     +Y
Sbjct: 7   TAPEQPAGEMENQTKPPDPRPDAPPEYNSHFLPGPPGTAVPP-----PTGYPGGLPMGYY 61

Query: 206 PPPVPFGYP-------------NQGRKNKPYRPIPVTWVPPP 234
            P  P  +P               G+   P + +P+TW+P P
Sbjct: 62  SPQQPSTFPLYQPVGGIHPVRYQPGKYPMPNQSVPITWMPGP 103


>gi|190194379 phospholipid scramblase 4 isoform a [Homo sapiens]
          Length = 329

 Score = 32.0 bits (71), Expect = 0.53
 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 20/102 (19%)

Query: 148 SSDEETSKEME--VKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMYRGNGHQNHY 205
           ++ E+ + EME   KP      A P Y    L  PP     P     P  Y G     +Y
Sbjct: 7   TAPEQPAGEMENQTKPPDPRPDAPPEYNSHFLPGPPGTAVPP-----PTGYPGGLPMGYY 61

Query: 206 PPPVPFGYP-------------NQGRKNKPYRPIPVTWVPPP 234
            P  P  +P               G+   P + +P+TW+P P
Sbjct: 62  SPQQPSTFPLYQPVGGIHPVRYQPGKYPMPNQSVPITWMPGP 103


>gi|190194377 phospholipid scramblase 4 isoform a [Homo sapiens]
          Length = 329

 Score = 32.0 bits (71), Expect = 0.53
 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 20/102 (19%)

Query: 148 SSDEETSKEME--VKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMYRGNGHQNHY 205
           ++ E+ + EME   KP      A P Y    L  PP     P     P  Y G     +Y
Sbjct: 7   TAPEQPAGEMENQTKPPDPRPDAPPEYNSHFLPGPPGTAVPP-----PTGYPGGLPMGYY 61

Query: 206 PPPVPFGYP-------------NQGRKNKPYRPIPVTWVPPP 234
            P  P  +P               G+   P + +P+TW+P P
Sbjct: 62  SPQQPSTFPLYQPVGGIHPVRYQPGKYPMPNQSVPITWMPGP 103


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 32.0 bits (71), Expect = 0.53
 Identities = 29/104 (27%), Positives = 40/104 (38%), Gaps = 10/104 (9%)

Query: 137 KVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELI-----FPPLPMWHPLPRK 191
           +++ D    +  +  +  K M V P +   AA  V   +  +     FPPLP   P P  
Sbjct: 640 EISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPP 699

Query: 192 KPGMYRGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPV-TWVPPP 234
           +PG           PPP P   P       P  P+P    VPPP
Sbjct: 700 QPGF----PMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPP 739



 Score = 28.1 bits (61), Expect = 7.6
 Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 17/68 (25%)

Query: 168  ASPVYQISELIFP-PLPMWHPLPRKKPGMYRGNGHQNHYPPPVPFGYPNQGRKNKPYRPI 226
            ASPV   + L  P PLP+  PLP   P + R    Q   P P+P           P  P 
Sbjct: 1420 ASPVLLETGLPLPLPLPL--PLPLALPAVLRA---QARAPTPLP-----------PLLPA 1463

Query: 227  PVTWVPPP 234
            P+   PPP
Sbjct: 1464 PLASCPPP 1471


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score = 31.6 bits (70), Expect = 0.69
 Identities = 33/144 (22%), Positives = 57/144 (39%), Gaps = 25/144 (17%)

Query: 102 CCRYGEKNNAFIVASFENKDENKDEISRKVTRAL-------DKVTSDYHSGSSSSDEETS 154
           C R GE+ + +   SF NK ++ +     ++ +L       D++  + ++   +     +
Sbjct: 108 CSRVGEEEHVY---SFPNKQKSAEPSPTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPA 164

Query: 155 KEMEVKPSSVTAAASPVYQISELIFPPLPMWHPLPRKKPGMYRGNG-------------- 200
            E    P  +  A SP+Y + E   P      PL ++KP    G G              
Sbjct: 165 DEANSSPP-LPGALSPLYGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDE 223

Query: 201 HQNHYPPPVPFGYPNQGRKNKPYR 224
            ++  P PVP    NQG  + P R
Sbjct: 224 LESSVPSPVPAITVNQGEMSSPQR 247


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,137,792
Number of Sequences: 37866
Number of extensions: 697343
Number of successful extensions: 2667
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 2582
Number of HSP's gapped (non-prelim): 183
length of query: 252
length of database: 18,247,518
effective HSP length: 100
effective length of query: 152
effective length of database: 14,460,918
effective search space: 2198059536
effective search space used: 2198059536
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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