Guide to the Human Genome
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Search of human proteins with 28827801

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28827801 breast cancer membrane protein 11 [Homo sapiens]
         (166 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28827801 breast cancer membrane protein 11 [Homo sapiens]          334   2e-92
gi|5453541 anterior gradient 2 homolog [Homo sapiens]                 214   3e-56
gi|7705696 thioredoxin domain containing 12 [Homo sapiens]             89   1e-18
gi|31542723 spermatogenesis associated 20 [Homo sapiens]               30   0.73 
gi|215982794 myosin VA isoform 2 [Homo sapiens]                        28   3.6  
gi|215982791 myosin VA isoform 1 [Homo sapiens]                        28   3.6  
gi|154277118 spectrin repeat containing, nuclear envelope 1 isof...    28   4.7  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    28   4.7  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    28   4.7  
gi|68303635 mutS homolog 3 [Homo sapiens]                              27   6.1  
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...    27   6.1  
gi|38093643 SET and MYND domain containing 1 [Homo sapiens]            27   6.1  
gi|45827701 pad-1-like [Homo sapiens]                                  27   6.1  
gi|122891870 melanoma inhibitory activity family, member 3 [Homo...    27   8.0  
gi|24307911 acid sphingomyelinase-like phosphodiesterase 3A [Hom...    27   8.0  
gi|11641283 LIM homeobox protein 5 [Homo sapiens]                      27   8.0  

>gi|28827801 breast cancer membrane protein 11 [Homo sapiens]
          Length = 166

 Score =  334 bits (856), Expect = 2e-92
 Identities = 166/166 (100%), Positives = 166/166 (100%)

Query: 1   MMLHSALGLCLLLVTVSSNLAIAIKKEKRPPQTLSRGWGDDITWVQTYEEGLFYAQKSKK 60
           MMLHSALGLCLLLVTVSSNLAIAIKKEKRPPQTLSRGWGDDITWVQTYEEGLFYAQKSKK
Sbjct: 1   MMLHSALGLCLLLVTVSSNLAIAIKKEKRPPQTLSRGWGDDITWVQTYEEGLFYAQKSKK 60

Query: 61  PLMVIHHLEDCQYSQALKKVFAQNEEIQEMAQNKFIMLNLMHETTDKNLSPDGQYVPRIM 120
           PLMVIHHLEDCQYSQALKKVFAQNEEIQEMAQNKFIMLNLMHETTDKNLSPDGQYVPRIM
Sbjct: 61  PLMVIHHLEDCQYSQALKKVFAQNEEIQEMAQNKFIMLNLMHETTDKNLSPDGQYVPRIM 120

Query: 121 FVDPSLTVRADIAGRYSNRLYTYEPRDLPLLIENMKKALRLIQSEL 166
           FVDPSLTVRADIAGRYSNRLYTYEPRDLPLLIENMKKALRLIQSEL
Sbjct: 121 FVDPSLTVRADIAGRYSNRLYTYEPRDLPLLIENMKKALRLIQSEL 166


>gi|5453541 anterior gradient 2 homolog [Homo sapiens]
          Length = 175

 Score =  214 bits (545), Expect = 3e-56
 Identities = 108/167 (64%), Positives = 136/167 (81%), Gaps = 12/167 (7%)

Query: 11  LLLVTVSSNLA--IAIK-------KEKRP--PQTLSRGWGDDITWVQTYEEGLFYAQKSK 59
           LLLV +S  LA    +K       K+ RP  PQTLSRGWGD + W QTYEE L+ ++ S 
Sbjct: 10  LLLVALSYTLARDTTVKPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEEALYKSKTSN 69

Query: 60  KPLMVIHHLEDCQYSQALKKVFAQNEEIQEMAQNKFIMLNLMHETTDKNLSPDGQYVPRI 119
           KPLM+IHHL++C +SQALKKVFA+N+EIQ++A+ +F++LNL++ETTDK+LSPDGQYVPRI
Sbjct: 70  KPLMIIHHLDECPHSQALKKVFAENKEIQKLAE-QFVLLNLVYETTDKHLSPDGQYVPRI 128

Query: 120 MFVDPSLTVRADIAGRYSNRLYTYEPRDLPLLIENMKKALRLIQSEL 166
           MFVDPSLTVRADI GRYSNRLY YEP D  LL++NMKKAL+L+++EL
Sbjct: 129 MFVDPSLTVRADITGRYSNRLYAYEPADTALLLDNMKKALKLLKTEL 175


>gi|7705696 thioredoxin domain containing 12 [Homo sapiens]
          Length = 172

 Score = 89.4 bits (220), Expect = 1e-18
 Identities = 59/154 (38%), Positives = 83/154 (53%), Gaps = 14/154 (9%)

Query: 7   LGLCLLLVTVSSNLAIAIKKEKRPPQTLSRGWGDDITWVQTYEEGLFYAQKSKKPLMVIH 66
           LG   LL+ +SS+              L +G+GD I W +T E+G   A  S  PLMVI 
Sbjct: 13  LGFSFLLLVISSD----------GHNGLGKGFGDHIHW-RTLEDGKKEAAASGLPLMVII 61

Query: 67  HLEDCQYSQALKKVFAQNEEIQEMAQNKFIMLNLM--HETTDKNLSPDGQYVPRIMFVDP 124
           H   C   +ALK  FA++ EI E++ N F+M+NL    E  D++ SPDG Y+PRI+F+DP
Sbjct: 62  HKSWCGACKALKPKFAESTEISELSHN-FVMVNLEDEEEPKDEDFSPDGGYIPRILFLDP 120

Query: 125 SLTVRADIAGRYSNRLYTYEPRDLPLLIENMKKA 158
           S  V  +I     N  Y Y       +++ MK+A
Sbjct: 121 SGKVHPEIINENGNPSYKYFYVSAEQVVQGMKEA 154


>gi|31542723 spermatogenesis associated 20 [Homo sapiens]
          Length = 802

 Score = 30.4 bits (67), Expect = 0.73
 Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 1/76 (1%)

Query: 28  KRPPQTLSRGWGDDITWVQTYEEGLFYAQKSKKPLMVIHHLEDCQYSQALKKVFAQNEEI 87
           ++ P  L   + + + W    +E    A+K  KP+ +      C +   +++   QNEEI
Sbjct: 84  EKSPYLLQHAY-NPVDWYPWGQEAFDKARKENKPIFLSVGYSTCHWCHMMEEESFQNEEI 142

Query: 88  QEMAQNKFIMLNLMHE 103
             +    F+ + +  E
Sbjct: 143 GRLLSEDFVSVKVDRE 158


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score = 28.1 bits (61), Expect = 3.6
 Identities = 21/107 (19%), Positives = 41/107 (38%), Gaps = 5/107 (4%)

Query: 10  CLLLVTVSSNLAIAIKKEKRPPQTLSRGWGDDITWVQTYEEGLFYAQKSKKPLMVIHHLE 69
           C+ L+     +   + +E + P+     W   +      +  LF   +      +I H  
Sbjct: 495 CINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFA 554

Query: 70  D-----CQYSQALKKVFAQNEEIQEMAQNKFIMLNLMHETTDKNLSP 111
           D     C+      K     E+I+ +  +KF ML  + +  +K +SP
Sbjct: 555 DKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISP 601


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score = 28.1 bits (61), Expect = 3.6
 Identities = 21/107 (19%), Positives = 41/107 (38%), Gaps = 5/107 (4%)

Query: 10  CLLLVTVSSNLAIAIKKEKRPPQTLSRGWGDDITWVQTYEEGLFYAQKSKKPLMVIHHLE 69
           C+ L+     +   + +E + P+     W   +      +  LF   +      +I H  
Sbjct: 495 CINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFA 554

Query: 70  D-----CQYSQALKKVFAQNEEIQEMAQNKFIMLNLMHETTDKNLSP 111
           D     C+      K     E+I+ +  +KF ML  + +  +K +SP
Sbjct: 555 DKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISP 601


>gi|154277118 spectrin repeat containing, nuclear envelope 1 isoform 4
            [Homo sapiens]
          Length = 3321

 Score = 27.7 bits (60), Expect = 4.7
 Identities = 16/56 (28%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 43   TWVQTYEEGLFYAQKSKKPLMVIHHLEDCQYSQALKKVFAQNEEIQEMAQNKFIML 98
            TW +T E+ L    +      V + L+DCQ  + L K  A+ +E++++ QN   ++
Sbjct: 1560 TWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIK--AKEKEVEKIEQNGLALI 1613


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 27.7 bits (60), Expect = 4.7
 Identities = 16/56 (28%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 43   TWVQTYEEGLFYAQKSKKPLMVIHHLEDCQYSQALKKVFAQNEEIQEMAQNKFIML 98
            TW +T E+ L    +      V + L+DCQ  + L K  A+ +E++++ QN   ++
Sbjct: 6965 TWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIK--AKEKEVEKIEQNGLALI 7018


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 27.7 bits (60), Expect = 4.7
 Identities = 16/56 (28%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 43   TWVQTYEEGLFYAQKSKKPLMVIHHLEDCQYSQALKKVFAQNEEIQEMAQNKFIML 98
            TW +T E+ L    +      V + L+DCQ  + L K  A+ +E++++ QN   ++
Sbjct: 7036 TWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIK--AKEKEVEKIEQNGLALI 7089


>gi|68303635 mutS homolog 3 [Homo sapiens]
          Length = 1137

 Score = 27.3 bits (59), Expect = 6.1
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 6/57 (10%)

Query: 65  IHHLE--DCQYSQALKKVFAQNEEIQEMAQN--KFIMLNLMHETTDKNLSPDGQYVP 117
           +HHL   DC +S  L KV  Q +  +   Q   K ++ N  H   D  L    QYVP
Sbjct: 825 VHHLATVDCIFS--LAKVAKQGDYCRPTVQEERKIVIKNGRHPVIDVLLGEQDQYVP 879


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score = 27.3 bits (59), Expect = 6.1
 Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 52  LFYAQKSKKPLMVIHHLEDCQYSQALKKVFAQ-NEEIQEMAQNKFIML 98
           LF  +KSK P +V    +D   S A  K F + NEE  E A +  +++
Sbjct: 375 LFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVI 422


>gi|38093643 SET and MYND domain containing 1 [Homo sapiens]
          Length = 490

 Score = 27.3 bits (59), Expect = 6.1
 Identities = 11/43 (25%), Positives = 23/43 (53%)

Query: 42  ITWVQTYEEGLFYAQKSKKPLMVIHHLEDCQYSQALKKVFAQN 84
           ++++Q +EE  FYA++     M ++H  + Q   A+ +    N
Sbjct: 361 LSYLQAFEEASFYARRMVDGYMKLYHPNNAQLGMAVMRAGLTN 403


>gi|45827701 pad-1-like [Homo sapiens]
          Length = 2298

 Score = 27.3 bits (59), Expect = 6.1
 Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 29/117 (24%)

Query: 9    LCLLLVTVSSNLAIAIKKE--KRPPQTLSRGWGDDITWVQTYEEGLFYAQKSKKPLMVIH 66
            L   L T+ ++  + + KE  KRPPQ      GD+                 K PL+ I 
Sbjct: 1722 LVCALSTLQTDTLLHLVKEVVKRPPQVKG---GDE-----------------KSPLVDIP 1761

Query: 67   HLEDCQYSQALKKVFAQNEEIQEMAQNKFIMLNLMHETTDKNLSPDGQYVPRIMFVD 123
             L+ C         F Q   +  + +N   +L ++ E+   NL+P G ++   M  D
Sbjct: 1762 VLQFCY-------AFLQRLPVPALQENFSSLLGVLKESVQLNLAPPGYFLLLSMLND 1811


>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
            sapiens]
          Length = 1907

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 22/93 (23%), Positives = 40/93 (43%), Gaps = 8/93 (8%)

Query: 16   VSSNLAIAIKKEKRPPQTLSRGWGDDITWVQTYEEGLFYAQKSKKPLMVIHHLEDCQYSQ 75
            +S  L   +K+     Q LS        + Q  +E   + Q+++K  M++   E  +Y  
Sbjct: 1216 ISEKLKTIMKENTELVQKLSN-------YEQKIKESKKHVQETRKQNMILSD-EAIKYKD 1267

Query: 76   ALKKVFAQNEEIQEMAQNKFIMLNLMHETTDKN 108
             +K +    E + + A+N  +ML    E   KN
Sbjct: 1268 KIKTLEKNQEILDDTAKNLRVMLESEREQNVKN 1300


>gi|24307911 acid sphingomyelinase-like phosphodiesterase 3A [Homo
           sapiens]
          Length = 453

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 33/150 (22%), Positives = 66/150 (44%), Gaps = 17/150 (11%)

Query: 31  PQTLSRGWGDDITWVQTYEEGLFYAQKSKKPLMVIHH-----LEDCQYSQALKKVFAQNE 85
           P  ++    D     +  E  L  +Q++K+ + +I H     L   Q   A+++ +  NE
Sbjct: 216 PNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYY--NE 273

Query: 86  EIQEMAQNKFIML-----NLMHETTDKNLSPDGQYVPRIMFVDPSLTVRADIAGRYSN-- 138
           ++ ++ Q    ++        H  +   LS         +FV P++T    +  + +N  
Sbjct: 274 KLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNP 333

Query: 139 --RLYTYEPRDLPLLIENMKKALRLIQSEL 166
             RL+ Y+PRD  LL + ++  L L ++ L
Sbjct: 334 GIRLFQYDPRDYKLL-DMLQYYLNLTEANL 362


>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
          Length = 402

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 15/79 (18%)

Query: 50  EGLFYAQKSKKPLMVIHHLEDCQYSQALKKVFAQNEEIQEMAQNKFIM------------ 97
           +G+  +   +K    + HL +C       K  +  EE+  + +NKF+             
Sbjct: 69  QGISPSDLVRKARSKVFHL-NCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSSSSLKE 127

Query: 98  --LNLMHETTDKNLSPDGQ 114
             LN +   TD++LSPD Q
Sbjct: 128 GSLNSVSSCTDRSLSPDLQ 146


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,925,552
Number of Sequences: 37866
Number of extensions: 228706
Number of successful extensions: 579
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 569
Number of HSP's gapped (non-prelim): 19
length of query: 166
length of database: 18,247,518
effective HSP length: 95
effective length of query: 71
effective length of database: 14,650,248
effective search space: 1040167608
effective search space used: 1040167608
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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