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Search of human proteins with 28372531
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28372531 protein phosphatase 4, regulatory subunit 2 [Homo
sapiens]
(417 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28372531 protein phosphatase 4, regulatory subunit 2 [Homo sa... 835 0.0
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 63 4e-10
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 58 1e-08
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 58 1e-08
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 56 7e-08
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 56 7e-08
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 56 7e-08
gi|210032580 SET domain containing 1B [Homo sapiens] 55 9e-08
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 55 2e-07
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 55 2e-07
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 55 2e-07
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 55 2e-07
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 55 2e-07
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 55 2e-07
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 54 2e-07
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 54 2e-07
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 54 2e-07
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 54 2e-07
gi|55741677 SET domain containing 1A [Homo sapiens] 54 3e-07
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 54 3e-07
gi|217330641 IWS1 homolog [Homo sapiens] 54 3e-07
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 53 4e-07
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 52 8e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 52 8e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 52 8e-07
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 52 8e-07
gi|55956788 nucleolin [Homo sapiens] 52 1e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens] 51 2e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 3e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 50 3e-06
>gi|28372531 protein phosphatase 4, regulatory subunit 2 [Homo
sapiens]
Length = 417
Score = 835 bits (2157), Expect = 0.0
Identities = 417/417 (100%), Positives = 417/417 (100%)
Query: 1 MDVERLQEALKDFEKRGKKEVCPVLDQFLCHVAKTGETMIQWSQFKGYFIFKLEKVMDDF 60
MDVERLQEALKDFEKRGKKEVCPVLDQFLCHVAKTGETMIQWSQFKGYFIFKLEKVMDDF
Sbjct: 1 MDVERLQEALKDFEKRGKKEVCPVLDQFLCHVAKTGETMIQWSQFKGYFIFKLEKVMDDF 60
Query: 61 RTSAPEPRGPPNPNVEYIPFDEMKERILKIVTGFNGIPFTIQRLCELLTDPRRNYTGTDK 120
RTSAPEPRGPPNPNVEYIPFDEMKERILKIVTGFNGIPFTIQRLCELLTDPRRNYTGTDK
Sbjct: 61 RTSAPEPRGPPNPNVEYIPFDEMKERILKIVTGFNGIPFTIQRLCELLTDPRRNYTGTDK 120
Query: 121 FLRGVEKNVMVVSCVYPSSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRP 180
FLRGVEKNVMVVSCVYPSSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRP
Sbjct: 121 FLRGVEKNVMVVSCVYPSSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRP 180
Query: 181 KVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEA 240
KVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEA
Sbjct: 181 KVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEA 240
Query: 241 EGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEED 300
EGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEED
Sbjct: 241 EGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEED 300
Query: 301 EEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLH 360
EEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLH
Sbjct: 301 EEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLH 360
Query: 361 SEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
SEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD
Sbjct: 361 SEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 63.2 bits (152), Expect = 4e-10
Identities = 64/293 (21%), Positives = 118/293 (40%), Gaps = 18/293 (6%)
Query: 136 YPSSE-KNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKV---------SLS 185
Y S E K+N N + +S S T S+ NG G + K S S
Sbjct: 493 YNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDS 552
Query: 186 APMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEV 245
++ +S+DS +++ + + SDSS S+S SS S + D+ ++
Sbjct: 553 DSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD 612
Query: 246 KRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDE 305
D + + +S++ S S ++ S+SS D + + + D
Sbjct: 613 SSDSSD-SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS 671
Query: 306 EEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSE 365
+ +S +S + N SD + + N S +++ +SD S + D +S S+
Sbjct: 672 SDSSDSSSSS-----DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS-SDSSNSNSSD 725
Query: 366 NEGPVSSSSSDCRETEELVGSNSSKTGEILSESS-MENDDEATEVTDEPMEQD 417
++ SS SSD + + S+ S S+SS N ++++ +D D
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778
Score = 61.6 bits (148), Expect = 1e-09
Identities = 57/281 (20%), Positives = 111/281 (39%), Gaps = 11/281 (3%)
Query: 138 SSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPEST 197
SS+ ++S+S N + NS +E SN + + S + ++N S
Sbjct: 900 SSDSDSSDSSNSSDS-SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958
Query: 198 DSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVR 257
S +N + + N SDSS S + S + + + + + +
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018
Query: 258 ETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSRE 317
+S ++ S SS +++S SS D + ++ + D + +S +S
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS-- 1076
Query: 318 MIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDC 377
+ + + SD + + N S +++ +S S D S S N SS SSD
Sbjct: 1077 ---DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN----SSDSSDS 1129
Query: 378 RETEELVGSNSSKTGEILSESSMEND-DEATEVTDEPMEQD 417
++ + S++S SESS +D ++++ +D D
Sbjct: 1130 SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170
Score = 61.2 bits (147), Expect = 2e-09
Identities = 45/218 (20%), Positives = 86/218 (39%), Gaps = 5/218 (2%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
+S+DSK + + + + SDS + S+ +S N + + + + +
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMT 314
+S ++ S SS +E+S SS D DS + + D +S +
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737
Query: 315 SREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSE-NEGPVSSS 373
S + S D + ++S+ +N + SD S + S S+ N+ SS
Sbjct: 738 SNSSDSSDSSDSSNSSD----SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793
Query: 374 SSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTD 411
SSD + + S+ S S+S N +++ +D
Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831
Score = 58.5 bits (140), Expect = 1e-08
Identities = 61/311 (19%), Positives = 115/311 (36%), Gaps = 45/311 (14%)
Query: 138 SSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLP--E 195
SS+ +NSNS + + NS ++ SN + + S + ++N +
Sbjct: 715 SSDSSNSNSSDSDSS-----NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769
Query: 196 STDSKEANLQQNE-EKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
S+DS +++ N + N S +S+ S+ S+ S N D+ ++ D +
Sbjct: 770 SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS---------DSDS 820
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMT 314
+S ++ S SS +++S SS D DS D + + S +
Sbjct: 821 SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880
Query: 315 SREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSEN-------- 366
E N SD + + + ++S+ +N + SD S + S S+N
Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940
Query: 367 --------------------EGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEA 406
+ SS SSD ++ SNSS + + S + ++
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 407 TEVTDEPMEQD 417
+ +D D
Sbjct: 1001 SNSSDSSDSSD 1011
Score = 58.2 bits (139), Expect = 1e-08
Identities = 56/289 (19%), Positives = 109/289 (37%), Gaps = 11/289 (3%)
Query: 138 SSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPEST 197
S ++S+S N N +S S S+ + + + S S+ + + +
Sbjct: 651 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710
Query: 198 DSKEANLQQNEEKNHSDSSTS--------ESEVSSVSPLKNKHPDEDAVEAEGHEVKRLR 249
DS +++ N + SDSS S S+ S S N D+ ++
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 250 FDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEE 309
D +S ++ S SS +++S+SS + ++ D +
Sbjct: 771 SDSSDS--SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN 828
Query: 310 ESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSE-NEG 368
S + + + SD + + + S+ +N + SD S + S+ S+ NE
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888
Query: 369 PVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
SS SSD + + S+SS + + S+ + E++ +D D
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937
Score = 57.4 bits (137), Expect = 2e-08
Identities = 57/275 (20%), Positives = 113/275 (41%), Gaps = 13/275 (4%)
Query: 139 SEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMT----TNGLP 194
S+ +NS+ + + NS ++ S+ + NR S S+ + ++
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Query: 195 ESTDSKEANLQQN-----EEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLR 249
+S+DS ++N N + N SDS +S+S SS S + D+ E+
Sbjct: 878 DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS--SDSSNSSDSSESSNSSDNSNS 935
Query: 250 FDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEE 309
D + S +S+ S ++ SS S D + + ++ + D +
Sbjct: 936 SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995
Query: 310 ESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSEN-EG 368
+S +S + +S ++ + + +S+ +N + SD S + S+ S++ +
Sbjct: 996 DSSDSSNSSDSSDSSDSSDSSNS-SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1054
Query: 369 PVSSSSSDCRETEELVGSNSSKTGEILSESSMEND 403
SS SSD ++ + S+ S SESS +D
Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089
Score = 57.0 bits (136), Expect = 3e-08
Identities = 59/286 (20%), Positives = 117/286 (40%), Gaps = 7/286 (2%)
Query: 138 SSEKNNSNSL-NRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPES 196
+S+ NNS+S N NG S S +S+ + + N S S+ ++ S
Sbjct: 518 TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577
Query: 197 TDS--KEANLQQNEEKNHSDSS-TSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKE 253
+DS +++ + + + SDSS +S+S SS S + D +++ + + D +
Sbjct: 578 SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSD 637
Query: 254 GEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFM 313
+ + S ++ S +S + +S+SS D ++ D + +S
Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN 697
Query: 314 TSR--EMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVS 371
+S + + +S D+ N S+ +N + SD S + D S S N S
Sbjct: 698 SSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS-SDSSDSSDSSNSSDSS 756
Query: 372 SSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
SS ++ S+SS + + + S + +++ +D D
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802
Score = 53.1 bits (126), Expect = 4e-07
Identities = 42/214 (19%), Positives = 95/214 (44%), Gaps = 4/214 (1%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
+S+DS +++ ++ + SDSS S S + + + + ++ + +
Sbjct: 1062 DSSDSSDSS-DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMT 314
+S ++ S SS +++S SS+ D ++ + D + +S +
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180
Query: 315 SREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSE-NEGPVSSS 373
S + +S D+ + + ++S+ ++ + SD S + S+ S+ NE SS
Sbjct: 1181 SDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239
Query: 374 SSDCRETEELV-GSNSSKTGEILSESSMENDDEA 406
SSD ++ S+SS + + S+S+ E+D ++
Sbjct: 1240 SSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273
Score = 51.6 bits (122), Expect = 1e-06
Identities = 45/231 (19%), Positives = 95/231 (41%), Gaps = 26/231 (11%)
Query: 194 PESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKE 253
P S+D N N E +++ SS ++ +S DE G + K E
Sbjct: 465 PNSSDESNGNDDANSESDNNSSSRGDASYNS---------DESKDNGNGSDSK----GAE 511
Query: 254 GEVRETASQTTSSEISSVMVGETEASSSSQDKDK-DSRCTRQHCTEEDEEEDEEEEEESF 312
+ ++ S T +S+ + ++ + D DK DS + ++ D + + S
Sbjct: 512 DDDSDSTSDTNNSDSNG------NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565
Query: 313 MTSREMIPERKNQE---KESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGP 369
+ + + + +SD + + + ++S+ +N + SD S + S+ S+++
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 370 VSSSSSDCRETE---ELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
S S SD +++ + SNSS + + S N +++ +D D
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676
Score = 49.3 bits (116), Expect = 6e-06
Identities = 54/282 (19%), Positives = 119/282 (42%), Gaps = 15/282 (5%)
Query: 138 SSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPEST 197
S N+S+S + + +S S + + + N S S+ + + +S+
Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS--DSS 1034
Query: 198 DSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVR 257
DS +++ ++ + SDSS S S S S + D+ ++ +
Sbjct: 1035 DSSDSS-DSSDSSDSSDSSDS-SNSSDSSDSSDSSDSSDSSDSSD--------SSDSSES 1084
Query: 258 ETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSRE 317
+S +++S SS +++S SS D + ++ + D + +S +S
Sbjct: 1085 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 1144
Query: 318 MIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSE-NEGPVSSSSSD 376
+ +S D+ + + ++S+ ++ + SD S + S+ S+ ++ SS SSD
Sbjct: 1145 SDSSESSDSSDSSDS-SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203
Query: 377 CRETEELVGSNSSKTGEILSESSMEND-DEATEVTDEPMEQD 417
++ + S+ S S+SS +D +E+++ +D D
Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSD 1245
Score = 47.8 bits (112), Expect = 2e-05
Identities = 44/226 (19%), Positives = 92/226 (40%), Gaps = 9/226 (3%)
Query: 195 ESTDSKEANLQQNEEKNHSDSS-TSESEVSSVSPLKNKHPD--EDAVEAEGHEVKRLRFD 251
+S+DS E++ ++ N SDSS +S+S SS S + D + + ++ +
Sbjct: 1077 DSSDSSESS-DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1135
Query: 252 KEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEES 311
+ +S ++ S SS +++S SS D + ++ + D + +S
Sbjct: 1136 SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1195
Query: 312 FMTSREMIPERKNQEKESDDALTVNE-----ETSEENNQMEESDVSQAEKDLLHSEGSEN 366
+S + +S D+ ++ ++S+ N + SD S + S+ S++
Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255
Query: 367 EGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDE 412
S+S E++ S + S+S E D +D+
Sbjct: 1256 SDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 33.1 bits (74), Expect = 0.48
Identities = 63/285 (22%), Positives = 104/285 (36%), Gaps = 32/285 (11%)
Query: 122 LRGVEKNVMVVSCVYPSSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPK 181
+ G E+N+ S +N+ + NR N GN+ T+ ++ G +
Sbjct: 124 IHGKEENITANGIQGQVSIIDNAGATNRSNT---NGNTDKNTQNGDVGDAGHNEDV--AV 178
Query: 182 VSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKN--KHPDEDAVE 239
V P G STD NE++ +S +E S ++P N ++ ++A
Sbjct: 179 VQEDGPQVA-GSNNSTD--------NEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEV 229
Query: 240 AEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEE 299
G + +G + E S G+ E + KD + Q +
Sbjct: 230 TPGTGEDAGLDNSDGSPSGNGADEDEDEGS----GDDEDEEAGNGKDSSNNSKGQEGQDH 285
Query: 300 DEEEDEEEEEESFMTSREMI-PERKNQEKESDDALTVNEETSEENNQ-MEESDVSQAEKD 357
+E+D + S+E PE K D ++ SEEN+ + E + SQ +D
Sbjct: 286 GKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSK--SEENSAGIPEDNGSQRIED 343
Query: 358 ---LLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESS 399
L H E E ++ S VG + K EI SS
Sbjct: 344 TQKLNHRESKRVENRITKESE-----THAVGKSQDKGIEIKGPSS 383
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/285 (23%), Positives = 108/285 (37%), Gaps = 45/285 (15%)
Query: 138 SSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPEST 197
+ +K + +RM PS R ++ P LS+ ++ N ST
Sbjct: 40 NEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKP------------LSSSVSNNKRIVST 87
Query: 198 DSKEANLQQNEEKNHS--------DSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLR 249
K A +NEE S D S +S P KN+ P++ V E +
Sbjct: 88 KGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQ-PEKTCVRKRDPERRAKS 146
Query: 250 FDKEGEVR---------ETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEED 300
+G R +SQ++ E++S G + SS D+ + TE +
Sbjct: 147 PTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQG-----NNTENE 201
Query: 301 EEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLH 360
EE EE+ EE E + E +++E D+ EE EE + EE + + E+D
Sbjct: 202 EEGVEEDVEED-----EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256
Query: 361 SEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDE 405
+ N+ S +SD S S G + S S + DE
Sbjct: 257 QKEEGNDYDTRSEASDSGSE-----SVSFTDGSVRSGSGTDGSDE 296
Score = 35.0 bits (79), Expect = 0.13
Identities = 55/244 (22%), Positives = 103/244 (42%), Gaps = 41/244 (16%)
Query: 196 STDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGE 255
+ DS+E +++ E N D +E L N ++D E +G + K R +
Sbjct: 2 AADSRE---EKDGELNVLDDILTEVPEQD-DELYNPESEQDKNEKKGSKRKSDRMESTDT 57
Query: 256 VRETAS----QTTSSEISSVM-----VGETEASSSSQDKDKD-SRCTRQHCTEEDE---- 301
R+ S Q S +SS + + T+ S+++ K+++ R R + D
Sbjct: 58 KRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRL 117
Query: 302 ------EEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAE 355
E + + E++ + R+ PER+ + D + + E ++ SQ+
Sbjct: 118 SSSASREPYKNQPEKTCVRKRD--PERRAKSPTPDGSERIGLEVDRRASRS-----SQSS 170
Query: 356 KDLLHSE--GSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEP 413
K+ ++SE GS++E S SS + N+++ E E +E D+E E +E
Sbjct: 171 KEEVNSEEYGSDHETGSSGSSDE--------QGNNTENEEEGVEEDVEEDEEVEEDAEED 222
Query: 414 MEQD 417
E D
Sbjct: 223 EEVD 226
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/285 (23%), Positives = 108/285 (37%), Gaps = 45/285 (15%)
Query: 138 SSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPEST 197
+ +K + +RM PS R ++ P LS+ ++ N ST
Sbjct: 40 NEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKP------------LSSSVSNNKRIVST 87
Query: 198 DSKEANLQQNEEKNHS--------DSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLR 249
K A +NEE S D S +S P KN+ P++ V E +
Sbjct: 88 KGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQ-PEKTCVRKRDPERRAKS 146
Query: 250 FDKEGEVR---------ETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEED 300
+G R +SQ++ E++S G + SS D+ + TE +
Sbjct: 147 PTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQG-----NNTENE 201
Query: 301 EEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLH 360
EE EE+ EE E + E +++E D+ EE EE + EE + + E+D
Sbjct: 202 EEGVEEDVEED-----EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256
Query: 361 SEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDE 405
+ N+ S +SD S S G + S S + DE
Sbjct: 257 QKEEGNDYDTRSEASDSGSE-----SVSFTDGSVRSGSGTDGSDE 296
Score = 35.0 bits (79), Expect = 0.13
Identities = 55/244 (22%), Positives = 103/244 (42%), Gaps = 41/244 (16%)
Query: 196 STDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGE 255
+ DS+E +++ E N D +E L N ++D E +G + K R +
Sbjct: 2 AADSRE---EKDGELNVLDDILTEVPEQD-DELYNPESEQDKNEKKGSKRKSDRMESTDT 57
Query: 256 VRETAS----QTTSSEISSVM-----VGETEASSSSQDKDKD-SRCTRQHCTEEDE---- 301
R+ S Q S +SS + + T+ S+++ K+++ R R + D
Sbjct: 58 KRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRL 117
Query: 302 ------EEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAE 355
E + + E++ + R+ PER+ + D + + E ++ SQ+
Sbjct: 118 SSSASREPYKNQPEKTCVRKRD--PERRAKSPTPDGSERIGLEVDRRASRS-----SQSS 170
Query: 356 KDLLHSE--GSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEP 413
K+ ++SE GS++E S SS + N+++ E E +E D+E E +E
Sbjct: 171 KEEVNSEEYGSDHETGSSGSSDE--------QGNNTENEEEGVEEDVEEDEEVEEDAEED 222
Query: 414 MEQD 417
E D
Sbjct: 223 EEVD 226
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 55.8 bits (133), Expect = 7e-08
Identities = 70/284 (24%), Positives = 116/284 (40%), Gaps = 31/284 (10%)
Query: 139 SEKNNSNSLNRMNGV-MFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPEST 197
SE+ NS RMN M S +E++N G + L P + + + E
Sbjct: 225 SERGNS----RMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKI---FRKSRISEED 277
Query: 198 DSKEA--NLQQNEEKNHSDSSTSESEVSSVSPLKNKHPD--EDAVEAEGHEVKRLRFDKE 253
D E N E K+ S +++ + P ++ D ED+ E E + + +
Sbjct: 278 DRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQ---NVD 334
Query: 254 GEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFM 313
G E++ + S + + E S S+ + D + E+ E+ D EE+ S
Sbjct: 335 GPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSY---VEDQEDSDSSEEDSSHT 391
Query: 314 TSREMIPERKNQ-EKESDDALTVNEETSE----ENNQMEESDVSQAEKDLLHSEGSENEG 368
S R+ Q + ES ++L +EE+ E EN+ +E S + SE S +E
Sbjct: 392 LSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEE 451
Query: 369 PVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDE 412
S S R E+ SNS++ S+SS E D + + E
Sbjct: 452 DDSDSQDSSRSKED---SNSTE-----SKSSSEEDGQLKNIEIE 487
Score = 42.7 bits (99), Expect = 6e-04
Identities = 56/253 (22%), Positives = 101/253 (39%), Gaps = 23/253 (9%)
Query: 182 VSLSAPMTTNGLPESTDSKE--ANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVE 239
+S + P+T ES DS+E +L Q S +SE S N+ P +
Sbjct: 13 LSCALPVTRYQNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQS 72
Query: 240 AEG-----HE-VKRLRF-----------DKEGEVRETASQTTSSEISSVMVGETEASSSS 282
EG H+ + RL DK+ + ++ T + S + + +S
Sbjct: 73 EEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNS 132
Query: 283 Q-DKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPE-RKNQEKESDDALTVNEETS 340
+ D+DS T Q +EE + ++ +++ SRE+ E R + + E D+ +E
Sbjct: 133 RLGSDEDSDDTIQ-ASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEE 191
Query: 341 EENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSM 400
+ + S + L EG +++ P S S G S ++GE SE +
Sbjct: 192 HWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGE-NSEQAN 250
Query: 401 ENDDEATEVTDEP 413
D +++ + P
Sbjct: 251 TQDSGGSQLLEHP 263
Score = 39.3 bits (90), Expect = 0.007
Identities = 61/265 (23%), Positives = 106/265 (40%), Gaps = 64/265 (24%)
Query: 185 SAPMTTNGLPEST-DSKEA-NLQQNEEKNHSDSSTSESE-----VSSVSPLKNKHPDEDA 237
SAP + ++T +S+E N + + K ST ESE V S ++ H D
Sbjct: 150 SAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSE 209
Query: 238 VEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCT 297
++ EG ++ D +R S+ +S ++S + E+ +S
Sbjct: 210 LDDEG-----MQSDDPESIR---SERGNSRMNSAGMKSKESGENS--------------- 246
Query: 298 EEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEE--------- 348
E+ +D + SR++ RK++ E DD + ++NN MEE
Sbjct: 247 EQANTQDSGGSQLLEHPSRKIF--RKSRISEEDDRSEL-----DDNNTMEEVKSDSTENS 299
Query: 349 ---------------SDVSQAEKDLLHSEGSEN-EGPVSSSSSDCRETEELVGSNSSKTG 392
D + K+ L E S+N +GP S SS + + + S S +
Sbjct: 300 NSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQE-- 357
Query: 393 EILSESSMENDDEATEVTDEPMEQD 417
E++SES +N D T ++ + D
Sbjct: 358 EVVSESRGDNPDPTTSYVEDQEDSD 382
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 55.8 bits (133), Expect = 7e-08
Identities = 70/284 (24%), Positives = 116/284 (40%), Gaps = 31/284 (10%)
Query: 139 SEKNNSNSLNRMNGV-MFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPEST 197
SE+ NS RMN M S +E++N G + L P + + + E
Sbjct: 209 SERGNS----RMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKI---FRKSRISEED 261
Query: 198 DSKEA--NLQQNEEKNHSDSSTSESEVSSVSPLKNKHPD--EDAVEAEGHEVKRLRFDKE 253
D E N E K+ S +++ + P ++ D ED+ E E + + +
Sbjct: 262 DRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQ---NVD 318
Query: 254 GEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFM 313
G E++ + S + + E S S+ + D + E+ E+ D EE+ S
Sbjct: 319 GPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSY---VEDQEDSDSSEEDSSHT 375
Query: 314 TSREMIPERKNQ-EKESDDALTVNEETSE----ENNQMEESDVSQAEKDLLHSEGSENEG 368
S R+ Q + ES ++L +EE+ E EN+ +E S + SE S +E
Sbjct: 376 LSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEE 435
Query: 369 PVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDE 412
S S R E+ SNS++ S+SS E D + + E
Sbjct: 436 DDSDSQDSSRSKED---SNSTE-----SKSSSEEDGQLKNIEIE 471
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/227 (21%), Positives = 89/227 (39%), Gaps = 21/227 (9%)
Query: 206 QNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEG-----HE-VKRLRF--------- 250
QN E S+ + PL N+ P + EG H+ + RL
Sbjct: 23 QNNESEDSEEWKGHLAQAPTPPLANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKG 82
Query: 251 --DKEGEVRETASQTTSSEISSVMVGETEASSSSQ-DKDKDSRCTRQHCTEEDEEEDEEE 307
DK+ + ++ T + S + + +S+ D+DS T Q +EE + ++
Sbjct: 83 GDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQ-ASEESAPQGQDS 141
Query: 308 EEESFMTSREMIPE-RKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSEN 366
+++ SRE+ E R + + E D+ +E + + S + L EG ++
Sbjct: 142 AQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQS 201
Query: 367 EGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEP 413
+ P S S G S ++GE SE + D +++ + P
Sbjct: 202 DDPESIRSERGNSRMNSAGMKSKESGE-NSEQANTQDSGGSQLLEHP 247
Score = 39.3 bits (90), Expect = 0.007
Identities = 61/265 (23%), Positives = 106/265 (40%), Gaps = 64/265 (24%)
Query: 185 SAPMTTNGLPEST-DSKEA-NLQQNEEKNHSDSSTSESE-----VSSVSPLKNKHPDEDA 237
SAP + ++T +S+E N + + K ST ESE V S ++ H D
Sbjct: 134 SAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSE 193
Query: 238 VEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCT 297
++ EG ++ D +R S+ +S ++S + E+ +S
Sbjct: 194 LDDEG-----MQSDDPESIR---SERGNSRMNSAGMKSKESGENS--------------- 230
Query: 298 EEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEE--------- 348
E+ +D + SR++ RK++ E DD + ++NN MEE
Sbjct: 231 EQANTQDSGGSQLLEHPSRKIF--RKSRISEEDDRSEL-----DDNNTMEEVKSDSTENS 283
Query: 349 ---------------SDVSQAEKDLLHSEGSEN-EGPVSSSSSDCRETEELVGSNSSKTG 392
D + K+ L E S+N +GP S SS + + + S S +
Sbjct: 284 NSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQE-- 341
Query: 393 EILSESSMENDDEATEVTDEPMEQD 417
E++SES +N D T ++ + D
Sbjct: 342 EVVSESRGDNPDPTTSYVEDQEDSD 366
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 55.8 bits (133), Expect = 7e-08
Identities = 75/300 (25%), Positives = 117/300 (39%), Gaps = 69/300 (23%)
Query: 144 SNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPESTDSKEAN 203
S SLN+ G+SP S + P P P +R D ++ +
Sbjct: 248 SQSLNQPLTSSKAGSSPCLGSSSAASSP--PPPASR-----------------LDDEDGD 288
Query: 204 LQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRE----- 258
Q E++ D T E E + + + EA+ E++ LR + E + E
Sbjct: 289 FQPQEDEEEDDEETIEVE---------EQQEGNDAEAQRREIELLRREGELPLEELLRSL 339
Query: 259 ---------TASQTTSSEISSVMVGETEASSSS-----QDKDKDSRCTRQ-----HCTEE 299
+ SQT SS S G E + + K S T++ H E+
Sbjct: 340 PPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPDED 399
Query: 300 DEE----EDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEE--SDVSQ 353
DEE E+E E+EE + + E + E E D A+ ++E E MEE +
Sbjct: 400 DEEFTANEEEAEDEEDTIAAEEQL------EGEVDHAMELSELAREGELSMEELLQQYAG 453
Query: 354 AEKDLLHSEGSENEGPVSSSSSDCR-----ETEELVGSNSSKTGEILSESSMENDDEATE 408
A S E+E V ++SSDC E EE +SS + + + S + +DE +E
Sbjct: 454 AYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHSE 513
Score = 46.2 bits (108), Expect = 5e-05
Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 24/249 (9%)
Query: 150 MNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPESTDSKEANLQQNEE 209
+ G P +PS + +GP P+V P P S A Q+N++
Sbjct: 344 LEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKP------PPS-----AVTQRNKQ 392
Query: 210 KNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETA--SQTTSSE 267
H D E + + +ED + AE E D E+ E A + + E
Sbjct: 393 PWHPDEDDEEFTANE----EEAEDEEDTIAAE--EQLEGEVDHAMELSELAREGELSMEE 446
Query: 268 ISSVMVGE-TEASSSSQDKDKDS-RCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQ 325
+ G S SS+D+D+D C E E EE +E + + + +R
Sbjct: 447 LLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSED 506
Query: 326 EKE--SDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEEL 383
E++ S++ T SEE+ + EES+ +Q++ E ++ G + D ++E
Sbjct: 507 EEDEHSEEEETSGSSASEES-ESEESEDAQSQSQADEEEEDDDFGVEYLLARDEEQSEAD 565
Query: 384 VGSNSSKTG 392
GS G
Sbjct: 566 AGSGPPTPG 574
Score = 33.5 bits (75), Expect = 0.37
Identities = 38/160 (23%), Positives = 63/160 (39%), Gaps = 7/160 (4%)
Query: 263 TTSSEISSVMVGETEASSS-----SQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSRE 317
T+S SS +G + A+SS S+ D+D Q EED+EE E EE+ E
Sbjct: 256 TSSKAGSSPCLGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAE 315
Query: 318 MIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDC 377
R+ + + L + E Q+ E S ++ H + +GP + +
Sbjct: 316 -AQRREIELLRREGELPLEELLRSLPPQLLEGPSSPSQTPSSH-DSDTRDGPEEGAEEEP 373
Query: 378 RETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
+ E+ S+ T + DDE +E E +
Sbjct: 374 PQVLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDE 413
Score = 33.1 bits (74), Expect = 0.48
Identities = 39/192 (20%), Positives = 70/192 (36%), Gaps = 19/192 (9%)
Query: 189 TTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRL 248
TT + T + ++ E + S S E E +V+ + ++ AE E +
Sbjct: 2197 TTAYFKQQTIRELFDMPLEEPSSSSVPSAPEEEEETVASKQTHILEQALCRAEDEE--DI 2254
Query: 249 RFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEE 308
R + + + A +E GE E + EDEE E+
Sbjct: 2255 RAATQAKAEQVAELAEFNENDGFPAGEGEEAGRPG--------------AEDEEMSRAEQ 2300
Query: 309 EESFMTSREMIPER---KNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSE 365
E + + + ER K E ++ + +EE + D+ QA++++ E
Sbjct: 2301 EIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRLPQEE 2360
Query: 366 NEGPVSSSSSDC 377
EGP + S C
Sbjct: 2361 EEGPGAGDESSC 2372
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 55.5 bits (132), Expect = 9e-08
Identities = 50/186 (26%), Positives = 83/186 (44%), Gaps = 21/186 (11%)
Query: 237 AVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGET-----EASSSSQDKDKDSRC 291
+V+ E E +R +++ ++ +T + + V V E S ++ +K+S
Sbjct: 986 SVDEEDEESER---ERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLS 1042
Query: 292 TRQHCTEEDEE-EDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSE--ENNQMEE 348
Q TEE+EE E+EEEEE+ + E E+DD T E SE E + EE
Sbjct: 1043 EEQESTEEEEEAEEEEEEEDDDDDDSD-----DRDESENDDEDTALSEASEKDEGDSDEE 1097
Query: 349 SDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATE 408
VS ++ S+ SS SS+ + E S+S E+++ E ++E
Sbjct: 1098 ETVS-----IVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEM 1152
Query: 409 VTDEPM 414
V +E M
Sbjct: 1153 VAEESM 1158
Score = 49.3 bits (116), Expect = 6e-06
Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 16/126 (12%)
Query: 298 EEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQA-EK 356
EEDE+E EE+ES E E + +E+E DD +++ E N E++ +S+A EK
Sbjct: 1034 EEDEKESLSEEQES----TEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEK 1089
Query: 357 DLLHSEGSENEGPVSS-----SSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTD 411
D S+ E V+S SSS+ E+ E S+ S S SS E+++E +
Sbjct: 1090 DEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSES------SPSSSEDEEEVVAREE 1143
Query: 412 EPMEQD 417
E E++
Sbjct: 1144 EEEEEE 1149
Score = 45.4 bits (106), Expect = 9e-05
Identities = 51/178 (28%), Positives = 82/178 (46%), Gaps = 24/178 (13%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
EST+ +E ++ EE++ D + + + S ++ DED +E E D+E
Sbjct: 1046 ESTEEEEEAEEEEEEEDDDDDDSDDRDES-------ENDDEDTALSEASEKDEGDSDEEE 1098
Query: 255 EVRETASQ---TTSSEISSVMVGETEASSS-SQDKDKDSRCTRQHCTEEDEEEDEEE--E 308
V S+ T+SSE S E+ + SS S +D++ R EE+EEE+EEE
Sbjct: 1099 TVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAR----EEEEEEEEEEMVA 1154
Query: 309 EESFMTSREMIPERKNQEKE----SDDALTVNEETSEENNQMEESDVSQAEKDLLHSE 362
EES ++ PE Q+ E + A V+ EE +E V+ E+ + E
Sbjct: 1155 EESMASAG---PEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDE 1209
Score = 44.7 bits (104), Expect = 2e-04
Identities = 52/252 (20%), Positives = 90/252 (35%), Gaps = 23/252 (9%)
Query: 181 KVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEA 240
KV P T S D K + ++ +S + +P + D V
Sbjct: 963 KVKRKEPPDTTS---SGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGV 1019
Query: 241 EGHEVKRLRFDKEGEV--RETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQH--- 295
+ L D GE +E+ S+ S E E D D D R ++
Sbjct: 1020 RRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDE 1079
Query: 296 ------CTEEDEEEDEEEEEESFMTSR----EMIPERKNQEKESDDALTVNEETSEENNQ 345
+E+DE + +EEE S +TS+ ++ E ES + + EE
Sbjct: 1080 DTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVV 1139
Query: 346 MEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMEND-- 403
E + + E++++ E + GP D E G+ + + + E +E +
Sbjct: 1140 AREEEEEEEEEEMVAEESMASAGP-EDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAV 1198
Query: 404 --DEATEVTDEP 413
+E + DEP
Sbjct: 1199 APEERPSMLDEP 1210
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/161 (26%), Positives = 84/161 (52%), Gaps = 5/161 (3%)
Query: 238 VEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCT 297
V+ E E + L D + ++ ++ +T+S+E SS G ++++++ + +
Sbjct: 241 VKEEKMEERDLLSDLQ-DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 299
Query: 298 EEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKD 357
EE+EEE+EEEEEE+ S E ++ E+ S++ ++ +EE EN+ + + S+ ++D
Sbjct: 300 EEEEEEEEEEEEETGSNSEE--ASEQSAEEVSEEEMSEDEERENENHLLVVPE-SRFDRD 356
Query: 358 LLHSEGSENE-GPVSSSSSDCRETEELVGSNSSKTGEILSE 397
SE +E E G + SS E + + S + E+ E
Sbjct: 357 SGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 397
Score = 45.4 bits (106), Expect = 9e-05
Identities = 56/241 (23%), Positives = 85/241 (35%), Gaps = 23/241 (9%)
Query: 194 PESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDE-DAVEAEGHEVKRLRFDK 252
P+ KE + +EK E + +H +E D E KR +
Sbjct: 88 PQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR 147
Query: 253 EGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEES- 311
E RE E E Q K++ + R+ EE +E E E S
Sbjct: 148 EHSRRERDRLEQLERKR-----ERERKMREQQKEQREQKERERRAEERRKEREARREVSA 202
Query: 312 -FMTSRE------------MIPERKNQEKES--DDALTVNEETSEENNQMEE-SDVSQAE 355
T RE P R +E+ D V EE EE + + + D+S +E
Sbjct: 203 HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSE 262
Query: 356 KDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPME 415
+ +E S E S + E EE ++S+ E E E ++E ++E E
Sbjct: 263 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 322
Query: 416 Q 416
Q
Sbjct: 323 Q 323
Score = 39.7 bits (91), Expect = 0.005
Identities = 52/237 (21%), Positives = 93/237 (39%), Gaps = 43/237 (18%)
Query: 200 KEANLQQNEEKNH---SDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEV 256
KE + K H D + E E + +H + E E KR ++E ++
Sbjct: 114 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKR---ERERKM 170
Query: 257 RETASQTTSSEISSVMVGETEASSSSQDKDKDSR--CTRQHCTEEDEEEDEEE------- 307
RE + + E E + + K++++R + H T ++ D+ +
Sbjct: 171 REQQKEQREQK-------ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 223
Query: 308 ------EEESFMTSREMIPERKNQEKE-----SDDALTVNEETSEENNQMEESDVSQAEK 356
E R+ + E K +E++ D + + + +S E++ E S+ E+
Sbjct: 224 PPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEE 283
Query: 357 DLLHSEGSENEGPVSSSSSDCRETEEL----VGSNSSK----TGEILSESSMENDDE 405
+ E E EG S S + E EE GSNS + + E +SE M D+E
Sbjct: 284 E--EEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 338
Score = 36.2 bits (82), Expect = 0.057
Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 17/135 (12%)
Query: 202 ANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEG---HEVKRLRFDKEGEVRE 258
++LQ + SS S S S + + +E+ E EG E + ++E E E
Sbjct: 253 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 312
Query: 259 TASQTTSSEISSVMVGETEASSSSQDKDKDSR----CTRQHCTEEDEEEDEEEEEE---- 310
T S S E S E S+D+++++ + + D E EE EEE
Sbjct: 313 TGSN--SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 370
Query: 311 ----SFMTSREMIPE 321
S +T + +P+
Sbjct: 371 TPQSSALTEGDYVPD 385
Score = 28.9 bits (63), Expect = 9.0
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 196 STDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAV-EAEGH--EVKRLRFDK 252
S +S+E ++ EE+ + S++ E+ S + + ED E E H V RFD+
Sbjct: 296 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR 355
Query: 253 EGEVRETASQ 262
+ E A +
Sbjct: 356 DSGESEEAEE 365
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/161 (26%), Positives = 84/161 (52%), Gaps = 5/161 (3%)
Query: 238 VEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCT 297
V+ E E + L D + ++ ++ +T+S+E SS G ++++++ + +
Sbjct: 250 VKEEKMEERDLLSDLQ-DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 308
Query: 298 EEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKD 357
EE+EEE+EEEEEE+ S E ++ E+ S++ ++ +EE EN+ + + S+ ++D
Sbjct: 309 EEEEEEEEEEEEETGSNSEE--ASEQSAEEVSEEEMSEDEERENENHLLVVPE-SRFDRD 365
Query: 358 LLHSEGSENE-GPVSSSSSDCRETEELVGSNSSKTGEILSE 397
SE +E E G + SS E + + S + E+ E
Sbjct: 366 SGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 406
Score = 45.1 bits (105), Expect = 1e-04
Identities = 56/245 (22%), Positives = 87/245 (35%), Gaps = 22/245 (8%)
Query: 194 PESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDE-DAVEAEGHEVKRLRFDK 252
P+ KE + +EK E + +H +E D E KR +
Sbjct: 88 PQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR 147
Query: 253 EGEVRETASQTTSSEISSV----MVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEE 308
E RE + + E E Q K++ + R+ EE +E E
Sbjct: 148 EHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR 207
Query: 309 EES--FMTSRE------------MIPERKNQEKES--DDALTVNEETSEENNQMEE-SDV 351
E S T RE P R +E+ D V EE EE + + + D+
Sbjct: 208 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 267
Query: 352 SQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTD 411
S +E+ +E S E S + E EE ++S+ E E E ++E ++
Sbjct: 268 SDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE 327
Query: 412 EPMEQ 416
E EQ
Sbjct: 328 EASEQ 332
Score = 36.2 bits (82), Expect = 0.057
Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 17/135 (12%)
Query: 202 ANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEG---HEVKRLRFDKEGEVRE 258
++LQ + SS S S S + + +E+ E EG E + ++E E E
Sbjct: 262 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321
Query: 259 TASQTTSSEISSVMVGETEASSSSQDKDKDSR----CTRQHCTEEDEEEDEEEEEE---- 310
T S S E S E S+D+++++ + + D E EE EEE
Sbjct: 322 TGSN--SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 379
Query: 311 ----SFMTSREMIPE 321
S +T + +P+
Sbjct: 380 TPQSSALTEGDYVPD 394
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/161 (26%), Positives = 84/161 (52%), Gaps = 5/161 (3%)
Query: 238 VEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCT 297
V+ E E + L D + ++ ++ +T+S+E SS G ++++++ + +
Sbjct: 218 VKEEKMEERDLLSDLQ-DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 276
Query: 298 EEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKD 357
EE+EEE+EEEEEE+ S E ++ E+ S++ ++ +EE EN+ + + S+ ++D
Sbjct: 277 EEEEEEEEEEEEETGSNSEE--ASEQSAEEVSEEEMSEDEERENENHLLVVPE-SRFDRD 333
Query: 358 LLHSEGSENE-GPVSSSSSDCRETEELVGSNSSKTGEILSE 397
SE +E E G + SS E + + S + E+ E
Sbjct: 334 SGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 374
Score = 43.9 bits (102), Expect = 3e-04
Identities = 50/223 (22%), Positives = 89/223 (39%), Gaps = 19/223 (8%)
Query: 200 KEANLQQNEEKNH---SDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEV 256
KE + K H D + E E + +H + E E KR ++E ++
Sbjct: 91 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKR---ERERKM 147
Query: 257 RETASQTTSSEISSVMVGETEASSSSQDKDKDSR--CTRQHCTEEDEEEDEEEEEESFMT 314
RE + + E E + + K++++R + H T ++ D+ + S +
Sbjct: 148 REQQKEQREQK-------ERERRAEERRKEREARREVSAHHRTMREDYSDKVKA--SHWS 198
Query: 315 SREMIPERKNQEKESDDALTVNEETSEENNQMEE-SDVSQAEKDLLHSEGSENEGPVSSS 373
P R+ E D V EE EE + + + D+S +E+ +E S E S
Sbjct: 199 RSPPRPPRERFEL-GDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 257
Query: 374 SSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQ 416
+ E EE ++S+ E E E ++E ++E EQ
Sbjct: 258 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 300
Score = 36.2 bits (82), Expect = 0.057
Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 17/135 (12%)
Query: 202 ANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEG---HEVKRLRFDKEGEVRE 258
++LQ + SS S S S + + +E+ E EG E + ++E E E
Sbjct: 230 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 289
Query: 259 TASQTTSSEISSVMVGETEASSSSQDKDKDSR----CTRQHCTEEDEEEDEEEEEE---- 310
T S S E S E S+D+++++ + + D E EE EEE
Sbjct: 290 TGSN--SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 347
Query: 311 ----SFMTSREMIPE 321
S +T + +P+
Sbjct: 348 TPQSSALTEGDYVPD 362
Score = 28.9 bits (63), Expect = 9.0
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 196 STDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAV-EAEGH--EVKRLRFDK 252
S +S+E ++ EE+ + S++ E+ S + + ED E E H V RFD+
Sbjct: 273 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR 332
Query: 253 EGEVRETASQ 262
+ E A +
Sbjct: 333 DSGESEEAEE 342
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/161 (26%), Positives = 84/161 (52%), Gaps = 5/161 (3%)
Query: 238 VEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCT 297
V+ E E + L D + ++ ++ +T+S+E SS G ++++++ + +
Sbjct: 207 VKEEKMEERDLLSDLQ-DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 265
Query: 298 EEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKD 357
EE+EEE+EEEEEE+ S E ++ E+ S++ ++ +EE EN+ + + S+ ++D
Sbjct: 266 EEEEEEEEEEEEETGSNSEE--ASEQSAEEVSEEEMSEDEERENENHLLVVPE-SRFDRD 322
Query: 358 LLHSEGSENE-GPVSSSSSDCRETEELVGSNSSKTGEILSE 397
SE +E E G + SS E + + S + E+ E
Sbjct: 323 SGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 363
Score = 45.4 bits (106), Expect = 9e-05
Identities = 56/241 (23%), Positives = 85/241 (35%), Gaps = 23/241 (9%)
Query: 194 PESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDE-DAVEAEGHEVKRLRFDK 252
P+ KE + +EK E + +H +E D E KR +
Sbjct: 54 PQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR 113
Query: 253 EGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEES- 311
E RE E E Q K++ + R+ EE +E E E S
Sbjct: 114 EHSRRERDRLEQLERKR-----ERERKMREQQKEQREQKERERRAEERRKEREARREVSA 168
Query: 312 -FMTSRE------------MIPERKNQEKES--DDALTVNEETSEENNQMEE-SDVSQAE 355
T RE P R +E+ D V EE EE + + + D+S +E
Sbjct: 169 HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSE 228
Query: 356 KDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPME 415
+ +E S E S + E EE ++S+ E E E ++E ++E E
Sbjct: 229 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 288
Query: 416 Q 416
Q
Sbjct: 289 Q 289
Score = 39.7 bits (91), Expect = 0.005
Identities = 52/237 (21%), Positives = 93/237 (39%), Gaps = 43/237 (18%)
Query: 200 KEANLQQNEEKNH---SDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEV 256
KE + K H D + E E + +H + E E KR ++E ++
Sbjct: 80 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKR---ERERKM 136
Query: 257 RETASQTTSSEISSVMVGETEASSSSQDKDKDSR--CTRQHCTEEDEEEDEEE------- 307
RE + + E E + + K++++R + H T ++ D+ +
Sbjct: 137 REQQKEQREQK-------ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 189
Query: 308 ------EEESFMTSREMIPERKNQEKE-----SDDALTVNEETSEENNQMEESDVSQAEK 356
E R+ + E K +E++ D + + + +S E++ E S+ E+
Sbjct: 190 PPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEE 249
Query: 357 DLLHSEGSENEGPVSSSSSDCRETEEL----VGSNSSK----TGEILSESSMENDDE 405
+ E E EG S S + E EE GSNS + + E +SE M D+E
Sbjct: 250 E--EEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 304
Score = 36.2 bits (82), Expect = 0.057
Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 17/135 (12%)
Query: 202 ANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEG---HEVKRLRFDKEGEVRE 258
++LQ + SS S S S + + +E+ E EG E + ++E E E
Sbjct: 219 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 278
Query: 259 TASQTTSSEISSVMVGETEASSSSQDKDKDSR----CTRQHCTEEDEEEDEEEEEE---- 310
T S S E S E S+D+++++ + + D E EE EEE
Sbjct: 279 TGSN--SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 336
Query: 311 ----SFMTSREMIPE 321
S +T + +P+
Sbjct: 337 TPQSSALTEGDYVPD 351
Score = 28.9 bits (63), Expect = 9.0
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 196 STDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAV-EAEGH--EVKRLRFDK 252
S +S+E ++ EE+ + S++ E+ S + + ED E E H V RFD+
Sbjct: 262 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR 321
Query: 253 EGEVRETASQ 262
+ E A +
Sbjct: 322 DSGESEEAEE 331
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/161 (26%), Positives = 84/161 (52%), Gaps = 5/161 (3%)
Query: 238 VEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCT 297
V+ E E + L D + ++ ++ +T+S+E SS G ++++++ + +
Sbjct: 252 VKEEKMEERDLLSDLQ-DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 310
Query: 298 EEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKD 357
EE+EEE+EEEEEE+ S E ++ E+ S++ ++ +EE EN+ + + S+ ++D
Sbjct: 311 EEEEEEEEEEEEETGSNSEE--ASEQSAEEVSEEEMSEDEERENENHLLVVPE-SRFDRD 367
Query: 358 LLHSEGSENE-GPVSSSSSDCRETEELVGSNSSKTGEILSE 397
SE +E E G + SS E + + S + E+ E
Sbjct: 368 SGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 408
Score = 43.9 bits (102), Expect = 3e-04
Identities = 50/223 (22%), Positives = 89/223 (39%), Gaps = 19/223 (8%)
Query: 200 KEANLQQNEEKNH---SDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEV 256
KE + K H D + E E + +H + E E KR ++E ++
Sbjct: 125 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKR---ERERKM 181
Query: 257 RETASQTTSSEISSVMVGETEASSSSQDKDKDSR--CTRQHCTEEDEEEDEEEEEESFMT 314
RE + + E E + + K++++R + H T ++ D+ + S +
Sbjct: 182 REQQKEQREQK-------ERERRAEERRKEREARREVSAHHRTMREDYSDKVKA--SHWS 232
Query: 315 SREMIPERKNQEKESDDALTVNEETSEENNQMEE-SDVSQAEKDLLHSEGSENEGPVSSS 373
P R+ E D V EE EE + + + D+S +E+ +E S E S
Sbjct: 233 RSPPRPPRERFEL-GDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 291
Query: 374 SSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQ 416
+ E EE ++S+ E E E ++E ++E EQ
Sbjct: 292 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 334
Score = 36.2 bits (82), Expect = 0.057
Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 17/135 (12%)
Query: 202 ANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEG---HEVKRLRFDKEGEVRE 258
++LQ + SS S S S + + +E+ E EG E + ++E E E
Sbjct: 264 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 323
Query: 259 TASQTTSSEISSVMVGETEASSSSQDKDKDSR----CTRQHCTEEDEEEDEEEEEE---- 310
T S S E S E S+D+++++ + + D E EE EEE
Sbjct: 324 TGSN--SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 381
Query: 311 ----SFMTSREMIPE 321
S +T + +P+
Sbjct: 382 TPQSSALTEGDYVPD 396
Score = 28.9 bits (63), Expect = 9.0
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 196 STDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAV-EAEGH--EVKRLRFDK 252
S +S+E ++ EE+ + S++ E+ S + + ED E E H V RFD+
Sbjct: 307 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR 366
Query: 253 EGEVRETASQ 262
+ E A +
Sbjct: 367 DSGESEEAEE 376
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/249 (22%), Positives = 97/249 (38%), Gaps = 42/249 (16%)
Query: 201 EANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETA 260
++ ++ + + SDS + + +S S D+D G + F + E +
Sbjct: 13 DSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGAS 72
Query: 261 SQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIP 320
+ S S +EAS S +D D QH E +DE+E S S
Sbjct: 73 HHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEA 132
Query: 321 E-------------RKNQEKESDDALTVNE--------------ETSEENNQMEESD--- 350
E R+++ +SDD N + S+++ +M+ +D
Sbjct: 133 EGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEE 192
Query: 351 ---VSQAEKDLLHSE---GSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMEN-D 403
+S E+ L E S++E PV+S + D E S+ + ++ E M+N D
Sbjct: 193 RPQLSDDERQQLSEEEKANSDDERPVASDNDD-----EKQNSDDEEQPQLSDEEKMQNSD 247
Query: 404 DEATEVTDE 412
DE + +DE
Sbjct: 248 DERPQASDE 256
Score = 49.3 bits (116), Expect = 6e-06
Identities = 64/296 (21%), Positives = 110/296 (37%), Gaps = 23/296 (7%)
Query: 138 SSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPEST 197
S ++S+ N +G G+ ER + P A + G +
Sbjct: 23 SGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHS-GSDNHS 81
Query: 198 DSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDA--------VEAEGHEVKRLR 249
+ + + +E +H D+ S+ + S S N DE EAEG E +
Sbjct: 82 ERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSE--KAH 139
Query: 250 FDKEGEVRETASQTTSSEISSVMVGETEASSSSQDK----DKDSRCTRQHCTEE----DE 301
D E RE S + E E A S +DK D D + E D+
Sbjct: 140 SDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDD 199
Query: 302 EEDEEEEEESFMTSREM-IPERKNQEKESDDALTVNEETSEENNQMEESDVSQA-EKDLL 359
E + EEE + E + + EK++ D + + EE Q + + QA +++
Sbjct: 200 ERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHR 259
Query: 360 HSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPME 415
HS+ E + S S+ +E++ + I S+S ++D E + M+
Sbjct: 260 HSDDEEEQDHKSESARGSDSEDEVL--RMKRKNAIASDSEADSDTEVPKDNSGTMD 313
Score = 38.5 bits (88), Expect = 0.011
Identities = 37/206 (17%), Positives = 86/206 (41%), Gaps = 14/206 (6%)
Query: 206 QNEEKNHSDSST----SESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETAS 261
+ EK HSD +S+ S ++N +E A+G + +L+ + E +
Sbjct: 133 EGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEE---RAQGSDEDKLQNSDDDEKMQNTD 189
Query: 262 QTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEE--DEEEEEESFMTSREMI 319
++S + E S+++ +S R ++ D+E+ ++EE+ +M
Sbjct: 190 DEERPQLS-----DDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQ 244
Query: 320 PERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRE 379
+ + SD+ +++ E++++ E + S +E ++L + S + SD
Sbjct: 245 NSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEV 304
Query: 380 TEELVGSNSSKTGEILSESSMENDDE 405
++ G+ G S + +D+
Sbjct: 305 PKDNSGTMDLFGGADDISSGSDGEDK 330
Score = 34.7 bits (78), Expect = 0.16
Identities = 45/176 (25%), Positives = 75/176 (42%), Gaps = 19/176 (10%)
Query: 251 DKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEE 310
D E E +++ S + S + AS S D+D+ + Q +E +D E+E
Sbjct: 13 DSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGD-SGQPSNKELFGDDSEDEGA 71
Query: 311 SFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPV 370
S + + N + SD+ +E + E+N + SDV Q ++ E+EG
Sbjct: 72 SHHSGSD------NHSERSDNRSEASERSDHEDN--DPSDVDQHSGSEAPND-DEDEGHR 122
Query: 371 SSSSSDCRETE--ELVGSNSSKTG-EILSESSME------NDDEATEVTDEPMEQD 417
S S E E E S+ K G E S+ S + +D+E + +DE Q+
Sbjct: 123 SDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQN 178
Score = 32.7 bits (73), Expect = 0.63
Identities = 30/166 (18%), Positives = 72/166 (43%), Gaps = 16/166 (9%)
Query: 258 ETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSRE 317
+ S+T I + + E + K ++ R E + E++ + +++
Sbjct: 510 DRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASY 569
Query: 318 MIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDC 377
+ P+R ++E+E ++++++ + + E E+ ++S S+ EG +
Sbjct: 570 LEPDRYDEEEEGEESISLAAIKNRYKGGIRE------ERARIYSSDSD-EGSEEDKAQRL 622
Query: 378 RETEELVGSNSSKTGEILSESSMENDDEATE------VTDEPMEQD 417
+ ++L S + GE + E+DD+A + ++DE E D
Sbjct: 623 LKAKKL---TSDEEGEPSGKRKAEDDDKANKKHKKYVISDEEEEDD 665
Score = 32.3 bits (72), Expect = 0.82
Identities = 19/98 (19%), Positives = 45/98 (45%), Gaps = 2/98 (2%)
Query: 209 EKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEI 268
E + D E S++ +KN++ + + E + D+ E + + ++
Sbjct: 571 EPDRYDEEEEGEESISLAAIKNRY--KGGIREERARIYSSDSDEGSEEDKAQRLLKAKKL 628
Query: 269 SSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEE 306
+S GE ++D DK ++ +++ ++EEED++
Sbjct: 629 TSDEEGEPSGKRKAEDDDKANKKHKKYVISDEEEEDDD 666
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 54.3 bits (129), Expect = 2e-07
Identities = 61/252 (24%), Positives = 98/252 (38%), Gaps = 34/252 (13%)
Query: 184 LSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGH 243
L+AP GL S + H S S++++ A E
Sbjct: 373 LNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGM-----AFEEPID 427
Query: 244 EVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQ----HCTEE 299
E K + + GE E AS+ + E S E EA +K+ + C ++ C+++
Sbjct: 428 EKKFEKTEDGGEFEEGASENNAKESSP----EKEAEEGCPEKESEEGCPKRGFEGSCSQK 483
Query: 300 DEEE--------DEEEEEESFMTSREMIPERKNQEKESDDALTVNEET-------SEENN 344
+ EE ++ ++ES + + E KES+D L E SEE++
Sbjct: 484 ESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDD 543
Query: 345 QMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDD 404
+ESD +EK +GSE E + D E GS +L + END
Sbjct: 544 SEKESDEDCSEKQ--SEDGSEREFEENGLEKDLDEE----GSEKELHENVLDKELEENDS 597
Query: 405 EATEVTDEPMEQ 416
E +E D+ E+
Sbjct: 598 ENSEFEDDGSEK 609
Score = 53.5 bits (127), Expect = 3e-07
Identities = 57/229 (24%), Positives = 99/229 (43%), Gaps = 27/229 (11%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
E DS++ + + EK D S E E + + K DE+ E E HE DKE
Sbjct: 540 EEDDSEKESDEDCSEKQSEDGSEREFEENGLE----KDLDEEGSEKELHENV---LDKEL 592
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEE------DEEEDEEEE 308
E ++ + + S ++ E E S D+D D + + E+ DE+EDEE
Sbjct: 593 EENDSENSEFEDDGSEKVLDE-EGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYA 651
Query: 309 EESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGS---- 364
+E + + ++K +E ++D+ L E +E+ + +V A++ L + S
Sbjct: 652 DEKGLEA----ADKKAEEGDADEKL-FEESDDKEDEDADGKEVEDADEKLFEDDDSNEKL 706
Query: 365 --ENEGPVSSSSSDCRETEELVGSNSSKTGEILSESS--MENDDEATEV 409
E E D E L G S + G + + SS + +DD+ ++
Sbjct: 707 FDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDDI 755
Score = 51.2 bits (121), Expect = 2e-06
Identities = 46/227 (20%), Positives = 89/227 (39%), Gaps = 12/227 (5%)
Query: 180 PKVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVE 239
PK N E+ +KE+ N+E T ESE K DED E
Sbjct: 499 PKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDD----SEKESDEDCSE 554
Query: 240 AEGHEVKRLRFDKEGEVRETASQTTSSEI-SSVMVGETEASSSSQDKDKDSRCTR----- 293
+ + F++ G ++ + + E+ +V+ E E + S + +D +
Sbjct: 555 KQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEE 614
Query: 294 --QHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDV 351
+ +ED +E EEEE+ + E++++E + L ++ +EE + E+
Sbjct: 615 GSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFE 674
Query: 352 SQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSES 398
+K+ ++G E E D E+L + ++ +S
Sbjct: 675 ESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDS 721
Score = 48.5 bits (114), Expect = 1e-05
Identities = 61/256 (23%), Positives = 99/256 (38%), Gaps = 40/256 (15%)
Query: 191 NGLPESTDSKEANL----QQNEE---KNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGH 243
N ES+ KEA +++EE K + S S+ E +P++ D E++
Sbjct: 447 NNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKK- 505
Query: 244 EVKRLRFDKEGEVRETASQTTSSEISSVMVGET-EASSSSQDKDKDSRCTRQHCTEEDEE 302
K L+ D E S+ ++ S VG T E+ +K+ D C+ + + E
Sbjct: 506 --KTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSER 563
Query: 303 EDEE-------EEEESFMTSREMIPERK-------NQEKESDDALTVNEETSEENNQMEE 348
E EE +EE S E + +++ N E E D + V +E E E+
Sbjct: 564 EFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDED 623
Query: 349 SDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESS-------ME 401
SD + E+D V SD +E EE + + +E E
Sbjct: 624 SDEKEEEEDTYEK--------VFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEE 675
Query: 402 NDDEATEVTDEPMEQD 417
+DD+ E D +D
Sbjct: 676 SDDKEDEDADGKEVED 691
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 54.3 bits (129), Expect = 2e-07
Identities = 61/252 (24%), Positives = 98/252 (38%), Gaps = 34/252 (13%)
Query: 184 LSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGH 243
L+AP GL S + H S S++++ A E
Sbjct: 373 LNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGM-----AFEEPID 427
Query: 244 EVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQ----HCTEE 299
E K + + GE E AS+ + E S E EA +K+ + C ++ C+++
Sbjct: 428 EKKFEKTEDGGEFEEGASENNAKESSP----EKEAEEGCPEKESEEGCPKRGFEGSCSQK 483
Query: 300 DEEE--------DEEEEEESFMTSREMIPERKNQEKESDDALTVNEET-------SEENN 344
+ EE ++ ++ES + + E KES+D L E SEE++
Sbjct: 484 ESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDD 543
Query: 345 QMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDD 404
+ESD +EK +GSE E + D E GS +L + END
Sbjct: 544 SEKESDEDCSEKQ--SEDGSEREFEENGLEKDLDEE----GSEKELHENVLDKELEENDS 597
Query: 405 EATEVTDEPMEQ 416
E +E D+ E+
Sbjct: 598 ENSEFEDDGSEK 609
Score = 53.5 bits (127), Expect = 3e-07
Identities = 57/229 (24%), Positives = 99/229 (43%), Gaps = 27/229 (11%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
E DS++ + + EK D S E E + + K DE+ E E HE DKE
Sbjct: 540 EEDDSEKESDEDCSEKQSEDGSEREFEENGLE----KDLDEEGSEKELHENV---LDKEL 592
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEE------DEEEDEEEE 308
E ++ + + S ++ E E S D+D D + + E+ DE+EDEE
Sbjct: 593 EENDSENSEFEDDGSEKVLDE-EGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYA 651
Query: 309 EESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGS---- 364
+E + + ++K +E ++D+ L E +E+ + +V A++ L + S
Sbjct: 652 DEKGLEA----ADKKAEEGDADEKL-FEESDDKEDEDADGKEVEDADEKLFEDDDSNEKL 706
Query: 365 --ENEGPVSSSSSDCRETEELVGSNSSKTGEILSESS--MENDDEATEV 409
E E D E L G S + G + + SS + +DD+ ++
Sbjct: 707 FDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDDI 755
Score = 51.2 bits (121), Expect = 2e-06
Identities = 46/227 (20%), Positives = 89/227 (39%), Gaps = 12/227 (5%)
Query: 180 PKVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVE 239
PK N E+ +KE+ N+E T ESE K DED E
Sbjct: 499 PKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDD----SEKESDEDCSE 554
Query: 240 AEGHEVKRLRFDKEGEVRETASQTTSSEI-SSVMVGETEASSSSQDKDKDSRCTR----- 293
+ + F++ G ++ + + E+ +V+ E E + S + +D +
Sbjct: 555 KQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEE 614
Query: 294 --QHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDV 351
+ +ED +E EEEE+ + E++++E + L ++ +EE + E+
Sbjct: 615 GSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFE 674
Query: 352 SQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSES 398
+K+ ++G E E D E+L + ++ +S
Sbjct: 675 ESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDS 721
Score = 48.5 bits (114), Expect = 1e-05
Identities = 61/256 (23%), Positives = 99/256 (38%), Gaps = 40/256 (15%)
Query: 191 NGLPESTDSKEANL----QQNEE---KNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGH 243
N ES+ KEA +++EE K + S S+ E +P++ D E++
Sbjct: 447 NNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKK- 505
Query: 244 EVKRLRFDKEGEVRETASQTTSSEISSVMVGET-EASSSSQDKDKDSRCTRQHCTEEDEE 302
K L+ D E S+ ++ S VG T E+ +K+ D C+ + + E
Sbjct: 506 --KTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSER 563
Query: 303 EDEE-------EEEESFMTSREMIPERK-------NQEKESDDALTVNEETSEENNQMEE 348
E EE +EE S E + +++ N E E D + V +E E E+
Sbjct: 564 EFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDED 623
Query: 349 SDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESS-------ME 401
SD + E+D V SD +E EE + + +E E
Sbjct: 624 SDEKEEEEDTYEK--------VFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEE 675
Query: 402 NDDEATEVTDEPMEQD 417
+DD+ E D +D
Sbjct: 676 SDDKEDEDADGKEVED 691
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 54.3 bits (129), Expect = 2e-07
Identities = 36/130 (27%), Positives = 72/130 (55%), Gaps = 4/130 (3%)
Query: 238 VEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCT 297
V+ E E + L D + ++ ++ +T+S+E SS G ++++++ + +
Sbjct: 240 VKEEKMEERDLLSDLQ-DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 298
Query: 298 EEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKD 357
EE+EEE+EEEEEE+ S E ++ E+ S++ ++ +EE EN+ + + S+ ++D
Sbjct: 299 EEEEEEEEEEEEETGSNSEE--ASEQSAEEVSEEEMSEDEERENENHLLVVPE-SRFDRD 355
Query: 358 LLHSEGSENE 367
SE +E E
Sbjct: 356 SGESEEAEEE 365
Score = 46.2 bits (108), Expect = 5e-05
Identities = 44/162 (27%), Positives = 68/162 (41%), Gaps = 16/162 (9%)
Query: 252 KEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEES 311
KE ++ E + +IS + A SSS + S +EEE+EEEEEE
Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS----------EEEEEEEEEEEE 290
Query: 312 FMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVS 371
++ E E + +E+E ++ N E + E + E S+ +E + +E P S
Sbjct: 291 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 350
Query: 372 SSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEP 413
D E+EE + GE +SS E V D P
Sbjct: 351 RFDRDSGESEEA----EEEVGEGTPQSSALT--EGDYVPDSP 386
Score = 43.5 bits (101), Expect = 4e-04
Identities = 54/240 (22%), Positives = 84/240 (35%), Gaps = 22/240 (9%)
Query: 194 PESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKE 253
P+ KE + +EK + + K ++D E KR +E
Sbjct: 88 PQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMARE 147
Query: 254 GEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEES-- 311
RE E E Q K++ + R+ EE +E E E S
Sbjct: 148 HSRRERDRLEQLERKR-----ERERKMREQQKEQREQKERERRAEERRKEREARREVSAH 202
Query: 312 FMTSRE------------MIPERKNQEKES--DDALTVNEETSEENNQMEE-SDVSQAEK 356
T RE P R +E+ D V EE EE + + + D+S +E+
Sbjct: 203 HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER 262
Query: 357 DLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQ 416
+E S E S + E EE ++S+ E E E ++E ++E EQ
Sbjct: 263 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 322
Score = 37.0 bits (84), Expect = 0.033
Identities = 45/221 (20%), Positives = 84/221 (38%), Gaps = 28/221 (12%)
Query: 202 ANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETAS 261
++LQ + SS S S S + + +E+ E EG + ++E E E
Sbjct: 252 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 311
Query: 262 QTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPE 321
++SE EAS S ++ +EE E+EE E+ + ++
Sbjct: 312 TGSNSE---------EASEQSAEE------------VSEEEMSEDEEREN--ENHLLVVP 348
Query: 322 RKNQEKESDDALTVNEETSE---ENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCR 378
+++S ++ EE E +++ + E D LL E + + CR
Sbjct: 349 ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCR 408
Query: 379 ETEELVGSNSSKTGE--ILSESSMENDDEATEVTDEPMEQD 417
EE N + G ++ + + DE + ME++
Sbjct: 409 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKE 449
Score = 28.9 bits (63), Expect = 9.0
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 196 STDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAV-EAEGH--EVKRLRFDK 252
S +S+E ++ EE+ + S++ E+ S + + ED E E H V RFD+
Sbjct: 295 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR 354
Query: 253 EGEVRETASQ 262
+ E A +
Sbjct: 355 DSGESEEAEE 364
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 54.3 bits (129), Expect = 2e-07
Identities = 36/130 (27%), Positives = 72/130 (55%), Gaps = 4/130 (3%)
Query: 238 VEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCT 297
V+ E E + L D + ++ ++ +T+S+E SS G ++++++ + +
Sbjct: 250 VKEEKMEERDLLSDLQ-DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 308
Query: 298 EEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKD 357
EE+EEE+EEEEEE+ S E ++ E+ S++ ++ +EE EN+ + + S+ ++D
Sbjct: 309 EEEEEEEEEEEEETGSNSEE--ASEQSAEEVSEEEMSEDEERENENHLLVVPE-SRFDRD 365
Query: 358 LLHSEGSENE 367
SE +E E
Sbjct: 366 SGESEEAEEE 375
Score = 46.2 bits (108), Expect = 5e-05
Identities = 44/162 (27%), Positives = 68/162 (41%), Gaps = 16/162 (9%)
Query: 252 KEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEES 311
KE ++ E + +IS + A SSS + S +EEE+EEEEEE
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGS----------EEEEEEEEEEEE 300
Query: 312 FMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVS 371
++ E E + +E+E ++ N E + E + E S+ +E + +E P S
Sbjct: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 360
Query: 372 SSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEP 413
D E+EE + GE +SS E V D P
Sbjct: 361 RFDRDSGESEEA----EEEVGEGTPQSSALT--EGDYVPDSP 396
Score = 42.4 bits (98), Expect = 8e-04
Identities = 46/215 (21%), Positives = 87/215 (40%), Gaps = 16/215 (7%)
Query: 205 QQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTT 264
++ + D + E E + +H + E E KR ++E ++RE +
Sbjct: 131 RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKR---ERERKMREQQKEQR 187
Query: 265 SSEISSVMVGETEASSSSQDKDKDSR--CTRQHCTEEDEEEDEEEEEESFMTSREMIPER 322
+ E E + + K++++R + H T ++ D+ + S + P R
Sbjct: 188 EQK-------ERERRAEERRKEREARREVSAHHRTMREDYSDKVKA--SHWSRSPPRPPR 238
Query: 323 KNQEKESDDALTVNEETSEENNQMEE-SDVSQAEKDLLHSEGSENEGPVSSSSSDCRETE 381
+ E D V EE EE + + + D+S +E+ +E S E S + E E
Sbjct: 239 ERFEL-GDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE 297
Query: 382 ELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQ 416
E ++S+ E E E ++E ++E EQ
Sbjct: 298 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 332
Score = 37.0 bits (84), Expect = 0.033
Identities = 45/221 (20%), Positives = 84/221 (38%), Gaps = 28/221 (12%)
Query: 202 ANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETAS 261
++LQ + SS S S S + + +E+ E EG + ++E E E
Sbjct: 262 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321
Query: 262 QTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPE 321
++SE EAS S ++ +EE E+EE E+ + ++
Sbjct: 322 TGSNSE---------EASEQSAEE------------VSEEEMSEDEEREN--ENHLLVVP 358
Query: 322 RKNQEKESDDALTVNEETSE---ENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCR 378
+++S ++ EE E +++ + E D LL E + + CR
Sbjct: 359 ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCR 418
Query: 379 ETEELVGSNSSKTGE--ILSESSMENDDEATEVTDEPMEQD 417
EE N + G ++ + + DE + ME++
Sbjct: 419 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKE 459
Score = 34.7 bits (78), Expect = 0.16
Identities = 46/233 (19%), Positives = 93/233 (39%), Gaps = 25/233 (10%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRL------ 248
+ DSK +L++ E ++H T + SP + ED++E G E L
Sbjct: 39 DDRDSKRDSLEEGELRDHCMEITIRN-----SPYRR----EDSMEDRGEEDDSLAIKPPQ 89
Query: 249 RFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEE 308
+ ++ +V + + E ++ K+++ ++H E+D+ E E
Sbjct: 90 QMSRKEKVHHRKDEKRKEKCRHHS-HSAEGGKHARVKEREHERRKRHREEQDKARREWER 148
Query: 309 EESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSE---GSE 365
++ REM E +E++ + L E + + ++ Q E++ E E
Sbjct: 149 QK----RREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 204
Query: 366 NEGPVSSSSSDCRE--TEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQ 416
VS+ RE ++++ S+ S++ E D V +E ME+
Sbjct: 205 ARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 257
Score = 28.9 bits (63), Expect = 9.0
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 196 STDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAV-EAEGH--EVKRLRFDK 252
S +S+E ++ EE+ + S++ E+ S + + ED E E H V RFD+
Sbjct: 305 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR 364
Query: 253 EGEVRETASQ 262
+ E A +
Sbjct: 365 DSGESEEAEE 374
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/189 (26%), Positives = 82/189 (43%), Gaps = 25/189 (13%)
Query: 220 SEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEAS 279
SE+S S K P A E E ++E E E T G+T+
Sbjct: 901 SEISEASEEKRPRPSTPAEEDEDDP------EQEKEAGEPGRPGTKPPKRDEERGKTQGK 954
Query: 280 ---SSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVN 336
S + D + + +++ +E+DEE+DEE+EE+ +++E+ D T
Sbjct: 955 HRKSFALDSEGEE-ASQESSSEKDEEDDEEDEED------------EDREEAVD---TTK 998
Query: 337 EETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILS 396
+ET + + EESD S S+G + S SSS + S+SS + S
Sbjct: 999 KETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSS 1058
Query: 397 ESSMENDDE 405
ESS E+++E
Sbjct: 1059 ESSSEDEEE 1067
Score = 43.5 bits (101), Expect = 4e-04
Identities = 45/192 (23%), Positives = 71/192 (36%), Gaps = 30/192 (15%)
Query: 193 LPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHP--DEDAVEAEGHEVKRLRF 250
+ E+++ K E++ D E E K P DE+ + +G K
Sbjct: 903 ISEASEEKRPRPSTPAEEDEDDPE-QEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFAL 961
Query: 251 DKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEE 310
D EGE ASQ +SSE + E ++D+D +E E D E+E
Sbjct: 962 DSEGE---EASQESSSE-------KDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDE-- 1009
Query: 311 SFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPV 370
E +S ++ ++ EN+ +S+ S + S S +
Sbjct: 1010 ---------------ESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSS 1054
Query: 371 SSSSSDCRETEE 382
SSSS E EE
Sbjct: 1055 SSSSESSSEDEE 1066
Score = 39.3 bits (90), Expect = 0.007
Identities = 34/155 (21%), Positives = 59/155 (38%), Gaps = 15/155 (9%)
Query: 171 PGTPRPLNRPKVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSES-----EVSSV 225
PGT P + + ++ +EA+ + + EK+ D E E
Sbjct: 937 PGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDT 996
Query: 226 SPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDK 285
+ + + D + E++ L D +GE T+ +SS SS + +SSSS
Sbjct: 997 TKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSS 1056
Query: 286 DKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIP 320
+S E++EEEE + + S P
Sbjct: 1057 SSES----------SSEDEEEEERPAALPSASPPP 1081
Score = 37.7 bits (86), Expect = 0.019
Identities = 37/168 (22%), Positives = 69/168 (41%), Gaps = 30/168 (17%)
Query: 276 TEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEK-------- 327
+E S +S++K R EEDE++ E+E+E P ++++E+
Sbjct: 901 SEISEASEEK----RPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHR 956
Query: 328 -----ESDDALTVNEETSEENNQMEESDVSQAEKDLL------HSEGSENEGPVSSSSSD 376
+S+ E +SE++ + +E D +++ +E S+ E S SSS
Sbjct: 957 KSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSK 1016
Query: 377 CR-------ETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
C E + S SS + S SS + ++ + E +D
Sbjct: 1017 CSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSED 1064
Score = 30.4 bits (67), Expect = 3.1
Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 5/45 (11%)
Query: 267 EISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEES 311
E V+V E E + K + + R+ EE EEE EEEEEES
Sbjct: 1337 EAPEVVVAEAE-----EPKPQQLQQQREEGEEEGEEEGEEEEEES 1376
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 53.9 bits (128), Expect = 3e-07
Identities = 38/144 (26%), Positives = 76/144 (52%), Gaps = 4/144 (2%)
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMT 314
++ ++ +T+S+E SS G ++++++ + +EE+EEE+EEEEEE+
Sbjct: 12 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 71
Query: 315 SREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENE-GPVSSS 373
S E ++ E+ S++ ++ +EE EN+ + + S+ ++D SE +E E G +
Sbjct: 72 SEE--ASEQSAEEVSEEEMSEDEERENENHLLVVPE-SRFDRDSGESEEAEEEVGEGTPQ 128
Query: 374 SSDCRETEELVGSNSSKTGEILSE 397
SS E + + S + E+ E
Sbjct: 129 SSALTEGDYVPDSPALSPIELKQE 152
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 12/131 (9%)
Query: 272 MVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDE--EEEEESFMTSREMIPERKNQEKES 329
++ + + S S+ K + + EEE+E EEEEE TS E E + +E+E
Sbjct: 6 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE 65
Query: 330 DDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSEN------EGPVSSSSSDCRETEEL 383
++ + +EE SE++ + +VS+ E +EN E S + E EE
Sbjct: 66 EETGSNSEEASEQSAE----EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 121
Query: 384 VGSNSSKTGEI 394
VG + ++ +
Sbjct: 122 VGEGTPQSSAL 132
Score = 42.4 bits (98), Expect = 8e-04
Identities = 45/218 (20%), Positives = 86/218 (39%), Gaps = 23/218 (10%)
Query: 204 LQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQT 263
L ++ + S+ TS +E SS +E+ E E ++EG E + +
Sbjct: 7 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE---------EEEGSTSEESEEE 57
Query: 264 TSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERK 323
E E E + + ++ S + + +EE+ EDEE E E+ + ++PE +
Sbjct: 58 EEEE-------EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLL---VVPESR 107
Query: 324 --NQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETE 381
ES++A E + +++ + E D L E + + CR E
Sbjct: 108 FDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVE 167
Query: 382 ELVGSNSSKTGE--ILSESSMENDDEATEVTDEPMEQD 417
E N + G ++ + + DE + ME++
Sbjct: 168 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKE 205
Score = 28.9 bits (63), Expect = 9.0
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Query: 196 STDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAV-EAEGH--EVKRLRFDK 252
S +S+E ++ EE+ + S++ E+ S + + ED E E H V RFD+
Sbjct: 51 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDR 110
Query: 253 EGEVRETASQ 262
+ E A +
Sbjct: 111 DSGESEEAEE 120
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/241 (20%), Positives = 98/241 (40%), Gaps = 19/241 (7%)
Query: 171 PGTPRPLNRPKVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKN 230
P PR + L P ++ E +A+ +NEE S SESE
Sbjct: 203 PPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESE--------- 253
Query: 231 KHPDEDAVEAEGHEVKRLRF---DKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDK 287
P A ++E E+ + R + E R AS + + E+ V ++E+ +
Sbjct: 254 DPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPAS 313
Query: 288 DSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQME 347
DS ++ E D++ + E+ EM + + + D + ++ EE ++ +
Sbjct: 314 DSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQ 373
Query: 348 ESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEAT 407
+ D + EK+ + ++ + V S S D EE S+K ++S++ + D +
Sbjct: 374 KMDSDEDEKEGEEEKVAKRKAAVLSDSED----EE---KASAKKSRVVSDADDSDSDAVS 426
Query: 408 E 408
+
Sbjct: 427 D 427
Score = 53.1 bits (126), Expect = 4e-07
Identities = 57/250 (22%), Positives = 101/250 (40%), Gaps = 34/250 (13%)
Query: 184 LSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGH 243
L P ++ E +A+ +NEE S SESE P K D + +A H
Sbjct: 268 LPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESE----GPQKGPASDSETEDASRH 323
Query: 244 EVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEE 303
+ K D RE + T M ++ S S D+ K H ++ +EEE
Sbjct: 324 KQKPESDDDSD--RENKGEDTE------MQNDSFHSDSHMDRKKF------HSSDSEEEE 369
Query: 304 DEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEG 363
++++ +S +E E+ + K + + + +EE + SD ++ D + +
Sbjct: 370 HKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKS 429
Query: 364 SENEGPVSSSSSD---------CRETEELVGSNSSKTGE-------ILSESSMENDDEAT 407
+ E ++S S + E ++L GS+S E I ES E ++E T
Sbjct: 430 GKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFT 489
Query: 408 EVTDEPMEQD 417
E +E++
Sbjct: 490 GFNQEDLEEE 499
Score = 52.4 bits (124), Expect = 8e-07
Identities = 54/223 (24%), Positives = 93/223 (41%), Gaps = 19/223 (8%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
E A+ + EE S +S SE+E LK + D ++ E H+ ++
Sbjct: 149 EDVGKHPASDSEIEELQKSPASDSETE----DALKPQISDSESEEPPRHQASDSENEEPP 204
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMT 314
+ R + S++ V E+E Q D ++ + + E ED + S
Sbjct: 205 KPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSE 264
Query: 315 SREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSS 374
+ E+ P+ + + ES+D N+ + EN ++ + VS SE+EGP +
Sbjct: 265 NEEL-PKPRISDSESEDPPR-NQASDSENEELPKPRVSD----------SESEGPQKGPA 312
Query: 375 SDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
SD ETE+ S + E +S EN E TE+ ++ D
Sbjct: 313 SDS-ETED--ASRHKQKPESDDDSDRENKGEDTEMQNDSFHSD 352
Score = 38.5 bits (88), Expect = 0.011
Identities = 31/144 (21%), Positives = 54/144 (37%), Gaps = 2/144 (1%)
Query: 274 GETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDAL 333
G E S ++ D++ + H + E ++ S S E+ ++ + + + A
Sbjct: 43 GSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAE 102
Query: 334 TVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGE 393
++ E+ SD E L SENE ++ +SD E VG + + E
Sbjct: 103 PPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASD--SENEDVGKHPASDSE 160
Query: 394 ILSESSMENDDEATEVTDEPMEQD 417
I D TE +P D
Sbjct: 161 IEELQKSPASDSETEDALKPQISD 184
Score = 37.4 bits (85), Expect = 0.025
Identities = 42/207 (20%), Positives = 88/207 (42%), Gaps = 9/207 (4%)
Query: 213 SDSSTSESEVSSVSPLKNKHPDEDAV-EAEGHEVKRLRF-DKEGEV--RETASQTTSSEI 268
SDS + E S +N+ P + + ++E E+ + + D E E R AS + + E+
Sbjct: 183 SDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEEL 242
Query: 269 SSVMVGETEASSSSQDKDKDSRCTR--QHCTEEDEEEDEEEEEESFMTSREM-IPERKNQ 325
+ ++E+ + + DS + + E ED + S + E+ P +
Sbjct: 243 PKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDS 302
Query: 326 EKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVG 385
E E ++ +E+ ++ ++ S + D ++G + E S SD +
Sbjct: 303 ESEGPQKGPASDSETEDASRHKQKPESDDDSD-RENKGEDTEMQNDSFHSDSHMDRKKFH 361
Query: 386 SNSSKTGEILSESSMENDDEATEVTDE 412
S+ S+ E + M++D++ E +E
Sbjct: 362 SSDSEEEE-HKKQKMDSDEDEKEGEEE 387
Score = 35.0 bits (79), Expect = 0.13
Identities = 47/231 (20%), Positives = 84/231 (36%), Gaps = 28/231 (12%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
+ +D A Q+E + SD +E +H D E H D+E
Sbjct: 9 DQSDDGGATPVQDERDSGSDGEDDVNE---------QHSGSDTGSVERHSENETS-DRED 58
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMT 314
+ + T S + + +++ S + KDS + E + E E+ +
Sbjct: 59 GLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGS 118
Query: 315 SREMIPERKNQEKESDDALTVNEETSEENN--------------QMEESDVSQAE-KDLL 359
E RK +S++ +N S+ N ++++S S +E +D L
Sbjct: 119 DSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDAL 178
Query: 360 HSE--GSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATE 408
+ SE+E P +SD E S E L + + +D E+ E
Sbjct: 179 KPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQV-SDSESEE 228
Score = 32.7 bits (73), Expect = 0.63
Identities = 33/143 (23%), Positives = 58/143 (40%), Gaps = 9/143 (6%)
Query: 195 ESTDSKEANLQQNEEK--NHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDK 252
+ DS E + EEK + S+SE + K DA +++ V DK
Sbjct: 373 QKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVS----DK 428
Query: 253 EGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESF 312
G+ +T + + E + + D +S ++ + E +EEEE F
Sbjct: 429 SGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEF 488
Query: 313 M-TSREMIPERK--NQEKESDDA 332
++E + E K Q KE++D+
Sbjct: 489 TGFNQEDLEEEKGETQVKEAEDS 511
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 53.1 bits (126), Expect = 4e-07
Identities = 54/219 (24%), Positives = 81/219 (36%), Gaps = 23/219 (10%)
Query: 195 ESTDSKEANLQQNE--EKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDK 252
E KE N + E E+ H + E + + + E E EG EV+ R +
Sbjct: 716 EQGHQKERNQEMEEGGEEEHGEGEEEEGDREE----EEEKEGEGKEEGEGEEVEGEREKE 771
Query: 253 EGEVRE---TASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEE 309
EGE ++ + E GE E + ++ ++ EE + E EEEEE
Sbjct: 772 EGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEE 831
Query: 310 ESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGP 369
E E + +E E ++ EE E EE + + E+ EG E EG
Sbjct: 832 EG---------EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEE-----EGEEGEGE 877
Query: 370 VSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATE 408
+ EE G + GE E E + E E
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Score = 50.4 bits (119), Expect = 3e-06
Identities = 55/223 (24%), Positives = 81/223 (36%), Gaps = 10/223 (4%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
E D E ++ E + E E V K + +E+ E EG E + ++EG
Sbjct: 789 EEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEE-EGEGEEEEGEGEEEEG 847
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMT 314
E E + E GE E + +++ EE E E EEEE E
Sbjct: 848 EGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG--EGEGEEEGEGEGEEEEGEG--- 902
Query: 315 SREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSS 374
E E + +E+E + EE EE E + + E + EG E EG
Sbjct: 903 EGEEEGEGEGEEEEGEGK---GEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEE 959
Query: 375 SDCRETEELVGSNSSKTGEILSESSM-ENDDEATEVTDEPMEQ 416
+ E G + GE E E + E E +E E+
Sbjct: 960 EEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002
Score = 47.4 bits (111), Expect = 2e-05
Identities = 54/223 (24%), Positives = 78/223 (34%), Gaps = 24/223 (10%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
E + KE +E+N E E + +E+ E EG E EG
Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKE--------EG 759
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDE-EEEEESFM 313
E E + E GE + + ++K Q EE+E E EE+EE
Sbjct: 760 EGEEVEGEREKEE------GERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813
Query: 314 TSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSS 373
+ E K + +E ++ EE E + E + + E EG E EG
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKG-EEEGEEGEGE---- 868
Query: 374 SSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQ 416
E EE G + GE E E + E E E E+
Sbjct: 869 ----EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907
Score = 46.6 bits (109), Expect = 4e-05
Identities = 48/218 (22%), Positives = 80/218 (36%), Gaps = 16/218 (7%)
Query: 199 SKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRE 258
S A Q+EE+ + E+ + P E E E + R +E E +E
Sbjct: 663 SSGAEHWQDEEREKGEKDKGRGEM--------ERPGEGEKELAEKEEWKKRDGEEQEQKE 714
Query: 259 TASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREM 318
+ G E ++++ D EE+EE++ E +EE E
Sbjct: 715 REQGHQKERNQEMEEGGEEEHGEGEEEEGDR--------EEEEEKEGEGKEEGEGEEVEG 766
Query: 319 IPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCR 378
E++ E++ ++ E+ EE +Q E + + EG E EG R
Sbjct: 767 EREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGER 826
Query: 379 ETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQ 416
E EE G + GE E ++E +E E+
Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE 864
Score = 45.8 bits (107), Expect = 7e-05
Identities = 50/214 (23%), Positives = 77/214 (35%), Gaps = 13/214 (6%)
Query: 198 DSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVR 257
+ +E ++ E+ + E E + + +E+ E EG E + EGE
Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEG-EGEGEE------EGEGEGE 913
Query: 258 ETASQTTSSEISSVMVGE---TEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMT 314
E + E GE E +D + + E+EE + E EEE
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973
Query: 315 SREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSS 374
E E + +E E + EE EE + EE + E++ E EG
Sbjct: 974 GEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE 1033
Query: 375 SDCRETEELVGSNSSKTGEILSESSMENDDEATE 408
+ E EE G K GE E + N +E E
Sbjct: 1034 GEEEEGEE-EGEEREKEGE--GEENRRNREEEEE 1064
Score = 43.9 bits (102), Expect = 3e-04
Identities = 51/233 (21%), Positives = 81/233 (34%), Gaps = 18/233 (7%)
Query: 192 GLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHP--------DEDAVEAEGH 243
G E D +E ++ E K + E E + K +E+ + EG
Sbjct: 738 GEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE 797
Query: 244 EVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEE 303
E + + GE +E + E+ E + ++++ + E+EE
Sbjct: 798 EEET---EGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG 854
Query: 304 DEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEG 363
+ + EEE E E E E ++ EE E + EE + E+ EG
Sbjct: 855 EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG--EGEG 912
Query: 364 SENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSM-ENDDEATEVTDEPME 415
E EG E EE G + GE E E ++E E E E
Sbjct: 913 EEEEGEGKGE----EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961
Score = 41.2 bits (95), Expect = 0.002
Identities = 52/230 (22%), Positives = 85/230 (36%), Gaps = 29/230 (12%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAV---EAEGHEVKRLRFD 251
E +E + EE+ + E E + + +E+ E EG E + +
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Query: 252 KEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEES 311
+EGE + E GE E +++ + E +E E E EEEE
Sbjct: 935 EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG--------EGEEGEGEGEEEEG 986
Query: 312 FMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDV-SQAEKDLLHSEGSENEGPV 370
E E + E+E ++ EE E + EE +V + E + EG E EG
Sbjct: 987 -----EGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE 1041
Query: 371 SSSSSD----------CRETEELVGSNSSKTGEILSESSMENDDEATEVT 410
+ RE EE +TGE E+ ++ +E +V+
Sbjct: 1042 EGEEREKEGEGEENRRNREEEEEEEGKYQETGE--EENERQDGEEYKKVS 1089
Score = 39.3 bits (90), Expect = 0.007
Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 4/125 (3%)
Query: 235 EDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDK---DSRC 291
E+ E EG E + ++EGE E + E GE E +++++ +
Sbjct: 967 EEEGEGEGEEGEGEGEEEEGE-GEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEV 1025
Query: 292 TRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDV 351
+ E EEE+ EEE E E R+N+E+E ++ E EEN + + +
Sbjct: 1026 EGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEY 1085
Query: 352 SQAEK 356
+ K
Sbjct: 1086 KKVSK 1090
Score = 35.4 bits (80), Expect = 0.097
Identities = 42/197 (21%), Positives = 70/197 (35%), Gaps = 18/197 (9%)
Query: 198 DSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVR 257
+ +E + EE + E E +E+ E EG E +EGE
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEE-------EEGEGE 965
Query: 258 ETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSRE 317
E E E ++++ + + EE+ E + EEEEE E
Sbjct: 966 GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEG-----E 1020
Query: 318 MIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDC 377
+ E + +E E + EE EE + E + ++ ++ E E EG + +
Sbjct: 1021 VEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNRE----EEEEEEGKYQETGEE- 1075
Query: 378 RETEELVGSNSSKTGEI 394
E E G K +I
Sbjct: 1076 -ENERQDGEEYKKVSKI 1091
Score = 29.6 bits (65), Expect = 5.3
Identities = 38/209 (18%), Positives = 82/209 (39%), Gaps = 24/209 (11%)
Query: 193 LPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDK 252
L ES S++ +Q E D T E+E+ + S +++ D + + L ++
Sbjct: 455 LQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMT--HIMSLNSNE 512
Query: 253 EG----EVRETASQTTSSEISS-VMVGETEASSSSQDKD--KDSRCTRQHCTE------- 298
+ V++ Q T E++ + E + S ++ K+ + +QH ++
Sbjct: 513 KSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQP 572
Query: 299 --------EDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESD 350
++E E EE+E + + I E++ + E + + + E + +D
Sbjct: 573 ATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTD 632
Query: 351 VSQAEKDLLHSEGSENEGPVSSSSSDCRE 379
++ + S G +GP C E
Sbjct: 633 KAEVSEGKAKSVGEAEDGPEGRGDGTCEE 661
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 52.4 bits (124), Expect = 8e-07
Identities = 67/306 (21%), Positives = 130/306 (42%), Gaps = 36/306 (11%)
Query: 103 RLCELLTDPRRNYTGTDKFLRGVEKNVMVVSCVYPSSEKNNSNSLNR-MNGVMFPGNSPS 161
+LC+L T R+ + +L V+ + S +N +++ NR +NG + GN
Sbjct: 60 QLCDLETKLRKEELSEEGYLAKVKSLLNK-----DLSLENGAHAYNREVNGRLENGNQAR 114
Query: 162 YTER----SNINGPGTPRPLNRPKVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSST 217
R ++ N P P+PL++P+ + PE + S + + T
Sbjct: 115 SEARRVGMADANSP--PKPLSKPRTPRRSKSDGEAKPEPSPSPRITRKSTRQ-------T 165
Query: 218 SESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETE 277
+ + + P K K P E++ A+ E + +++ + E + TS E
Sbjct: 166 TITSHFAKGPAKRK-PQEESERAKSDESIK---EEDKDQDEKRRRVTSRE-------RVA 214
Query: 278 ASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALT-VN 336
+++ ++ TR TE++EE DE+EE+ ++E P++K +E+ +A V
Sbjct: 215 RPLPAEEPERAKSGTR---TEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQ 271
Query: 337 EETSEENNQMEESDVSQAEKDLLHSEGSENEGP--VSSSSSDCRETEELVGSNSSKTGEI 394
+ E+ ++ +E KDL E + P V+ SD ++ +E T +
Sbjct: 272 ADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKE 331
Query: 395 LSESSM 400
+E M
Sbjct: 332 PTEKKM 337
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 52.4 bits (124), Expect = 8e-07
Identities = 55/238 (23%), Positives = 100/238 (42%), Gaps = 9/238 (3%)
Query: 158 NSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSST 217
NS S ++ P L R K+++S ES + K+ ++++E +
Sbjct: 1283 NSESDSDSEESKKPRYRHRLLRHKLTVSDG-------ESGEEKKTKPKEHKEVKGRNRRK 1335
Query: 218 SESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETE 277
SE S S + E+ E+E + R R K+ E+ E + + + +
Sbjct: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED 1395
Query: 278 ASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNE 337
+SS ++ ++ ++ EE+EEE+EEEE+E+ + +K ++ DD L
Sbjct: 1396 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKL--RT 1453
Query: 338 ETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEIL 395
ET + EE AE++ + E +S + C T +LV +T E L
Sbjct: 1454 ETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPL 1511
Score = 37.7 bits (86), Expect = 0.019
Identities = 48/223 (21%), Positives = 80/223 (35%), Gaps = 19/223 (8%)
Query: 198 DSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVR 257
+ K L + D S+S++E S+ ED + +KR+ E R
Sbjct: 1052 EKKRCKLLGKSSRKRQDCSSSDTEKYSMK--------EDGCNSSDKRLKRIELR---ERR 1100
Query: 258 ETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSRE 317
+S+ + EI S SS +K K R + + +E+ S +
Sbjct: 1101 NLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQA 1160
Query: 318 MIPERKNQEKESDDALTVNEETSEEN--NQMEESDVSQAEKDLLHSEGSE---NEGPVSS 372
I + + E DD ++ E +S+E + E+ V + S G E PV+
Sbjct: 1161 DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTV 1220
Query: 373 SSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPME 415
D E + EI + S + D + DEP E
Sbjct: 1221 DDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSS---DDEPEE 1260
Score = 36.2 bits (82), Expect = 0.057
Identities = 40/220 (18%), Positives = 88/220 (40%), Gaps = 7/220 (3%)
Query: 199 SKEANLQQNEEKNHSDSSTSESEVSSVSPLK-NKHPDEDAVEAEGHEVKRLRFDKEGEVR 257
SK + +++ + +D ++ + +K N DED + E + R K+ E
Sbjct: 1213 SKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNE-E 1271
Query: 258 ETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSRE 317
+ ++++S ++E S + + R R T D E EE++ + +
Sbjct: 1272 NPGDEEAKNQVNSESDSDSEESKKPRYRH---RLLRHKLTVSDGESGEEKKTKP--KEHK 1326
Query: 318 MIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDC 377
+ R ++ S+D+ + + S + ++ ES+ Q + + E S
Sbjct: 1327 EVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKK 1386
Query: 378 RETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
R ++ +SS+ E E ++E E +E E++
Sbjct: 1387 RRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE 1426
Score = 32.7 bits (73), Expect = 0.63
Identities = 36/145 (24%), Positives = 60/145 (41%), Gaps = 41/145 (28%)
Query: 216 STSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGE 275
S+ ESE +S P + + D + G + KE T+SSE +
Sbjct: 25 SSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKE-------EGTSSSE-------K 70
Query: 276 TEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTV 335
+++S SS+ K K S T+ E D+E+ ++E TV
Sbjct: 71 SKSSGSSRSKRKPSIVTKY--VESDDEKPLDDE-------------------------TV 103
Query: 336 NEETSEENNQMEESDVSQAEKDLLH 360
NE+ S EN++ + + S ++D LH
Sbjct: 104 NEDASNENSENDITMQSLPKEDGLH 128
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 52.4 bits (124), Expect = 8e-07
Identities = 55/238 (23%), Positives = 100/238 (42%), Gaps = 9/238 (3%)
Query: 158 NSPSYTERSNINGPGTPRPLNRPKVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSST 217
NS S ++ P L R K+++S ES + K+ ++++E +
Sbjct: 1321 NSESDSDSEESKKPRYRHRLLRHKLTVSDG-------ESGEEKKTKPKEHKEVKGRNRRK 1373
Query: 218 SESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETE 277
SE S S + E+ E+E + R R K+ E+ E + + + +
Sbjct: 1374 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED 1433
Query: 278 ASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNE 337
+SS ++ ++ ++ EE+EEE+EEEE+E+ + +K ++ DD L
Sbjct: 1434 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKL--RT 1491
Query: 338 ETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEIL 395
ET + EE AE++ + E +S + C T +LV +T E L
Sbjct: 1492 ETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPL 1549
Score = 37.7 bits (86), Expect = 0.019
Identities = 48/223 (21%), Positives = 80/223 (35%), Gaps = 19/223 (8%)
Query: 198 DSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVR 257
+ K L + D S+S++E S+ ED + +KR+ E R
Sbjct: 1090 EKKRCKLLGKSSRKRQDCSSSDTEKYSMK--------EDGCNSSDKRLKRIELR---ERR 1138
Query: 258 ETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSRE 317
+S+ + EI S SS +K K R + + +E+ S +
Sbjct: 1139 NLSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQA 1198
Query: 318 MIPERKNQEKESDDALTVNEETSEEN--NQMEESDVSQAEKDLLHSEGSE---NEGPVSS 372
I + + E DD ++ E +S+E + E+ V + S G E PV+
Sbjct: 1199 DITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTV 1258
Query: 373 SSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPME 415
D E + EI + S + D + DEP E
Sbjct: 1259 DDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSS---DDEPEE 1298
Score = 36.2 bits (82), Expect = 0.057
Identities = 40/220 (18%), Positives = 88/220 (40%), Gaps = 7/220 (3%)
Query: 199 SKEANLQQNEEKNHSDSSTSESEVSSVSPLK-NKHPDEDAVEAEGHEVKRLRFDKEGEVR 257
SK + +++ + +D ++ + +K N DED + E + R K+ E
Sbjct: 1251 SKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNE-E 1309
Query: 258 ETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSRE 317
+ ++++S ++E S + + R R T D E EE++ + +
Sbjct: 1310 NPGDEEAKNQVNSESDSDSEESKKPRYRH---RLLRHKLTVSDGESGEEKKTKP--KEHK 1364
Query: 318 MIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDC 377
+ R ++ S+D+ + + S + ++ ES+ Q + + E S
Sbjct: 1365 EVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKK 1424
Query: 378 RETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
R ++ +SS+ E E ++E E +E E++
Sbjct: 1425 RRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE 1464
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 52.4 bits (124), Expect = 8e-07
Identities = 53/237 (22%), Positives = 98/237 (41%), Gaps = 25/237 (10%)
Query: 198 DSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDED----------AVEAEGHEVKR 247
D K+ +++++ E ++S S+ E K K +D + + E + K
Sbjct: 320 DDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKD 379
Query: 248 LRFD--------KEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEE 299
R D K + ++ A + T S S + E+ + KDS+ + +
Sbjct: 380 ARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKN 439
Query: 300 DEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLL 359
DEE + + E + + E+K ++ D + + + E+ +M ESD+ + +KD
Sbjct: 440 DEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEM-ESDL-ELKKDKK 497
Query: 360 HSEGSENEGPVSSSSSDCRETEELVGS---NSSKTGEILSESSMENDDEATEVTDEP 413
HS+ E +G D R+ E + SSKTG S +D E+ E +P
Sbjct: 498 HSK--EKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKP 552
Score = 42.4 bits (98), Expect = 8e-04
Identities = 59/291 (20%), Positives = 115/291 (39%), Gaps = 52/291 (17%)
Query: 163 TERSNINGPGTPRPLNRPKVSLSAPMTTNGLPESTDSKEANLQ-----QNEEKNHSDSST 217
+++S + P N VS + +S +SK+ N + N +K+ S T
Sbjct: 172 SKKSKSSSETNPESQNSKTVSKNCSQKDK--KDSKNSKKTNTEFLHTKNNPKKDLKRSKT 229
Query: 218 SESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFD-----------KEGEVRETASQTTSS 266
S +S + + + D + + + + + FD K ++ T +
Sbjct: 230 SNDPISEICSENSLNVDFLMLVGQSDD-ESINFDAWLRNYSQNNSKNYSLKYTKYTKKDT 288
Query: 267 EISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESF-MTSREMIPERKNQ 325
+ ++ + E S S+D KDS+ +++ ++D+++D +++ ES S + ERK+
Sbjct: 289 KKNAKKSSDAE-SEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDT 347
Query: 326 EK-----------------------ESDDALTVNEETSEENNQMEESDVSQAEKDLLHSE 362
+K ES DA ++ + D + K + S
Sbjct: 348 KKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFST 407
Query: 363 GSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEP 413
SE+E S D E SKT ++ S++ND+E+T+ EP
Sbjct: 408 DSESELESKESQKD-----EKKDKKDSKTD---NKKSVKNDEESTDADSEP 450
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 52.0 bits (123), Expect = 1e-06
Identities = 42/168 (25%), Positives = 66/168 (39%), Gaps = 25/168 (14%)
Query: 191 NGLPESTDSKEANLQQNEEKNHSDSSTSESEV-------SSVSPLKNKHPDEDAVEAEGH 243
N E +D +E + + +E++ D E E+ ++ +P DED + E
Sbjct: 139 NAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDD 198
Query: 244 EVKRLRFDKEGEVRET-------ASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHC 296
+ D E E ET A++ + +V E E + D D
Sbjct: 199 DDDE-EDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDD 257
Query: 297 TEEDEEEDEEEEEESF----------MTSREMIPERKNQEKESDDALT 334
E+DEEE+EEEEEE M ++ PE K Q+ E + T
Sbjct: 258 DEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTT 305
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/140 (22%), Positives = 62/140 (44%), Gaps = 8/140 (5%)
Query: 278 ASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNE 337
A D+++D +EDE+EDE+E E + M + P ++++ E D
Sbjct: 140 AKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDD------- 192
Query: 338 ETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSE 397
E E+++ EE D + + ++G + V + + E E+ + + + E
Sbjct: 193 EDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD-DE 251
Query: 398 SSMENDDEATEVTDEPMEQD 417
++DDE E +E E++
Sbjct: 252 DDEDDDDEDDEEEEEEEEEE 271
Score = 42.7 bits (99), Expect = 6e-04
Identities = 32/140 (22%), Positives = 60/140 (42%), Gaps = 23/140 (16%)
Query: 278 ASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNE 337
A + K +DS +EEDEE+DE+E+E+ E + ++ A +E
Sbjct: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDE--------DEIEPAAMKAAAAAPASE 185
Query: 338 ETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSE 397
+ +E+++ +E D E D S + ET G ++K + ++
Sbjct: 186 DEDDEDDEDDEDDDDDEEDD---------------SEEEAMETTPAKGKKAAKVVPVKAK 230
Query: 398 SSMENDDEATEVTDEPMEQD 417
+ E++DE + DE + D
Sbjct: 231 NVAEDEDEEEDDEDEDDDDD 250
Score = 35.8 bits (81), Expect = 0.074
Identities = 31/143 (21%), Positives = 61/143 (42%), Gaps = 13/143 (9%)
Query: 235 EDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKD-KDSRCTR 293
ED+ E E + + D E E + EI + A+ +S+D+D +D
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDED------EDEIEPAAMKAAAAAPASEDEDDEDDEDDE 196
Query: 294 QHCTEEDEEEDEEEEEESFMTSR---EMIPERKNQEKESDDALTVNEETSEENNQMEESD 350
+E+++ +EE E + + +++P + E +D E+ +E++ +E D
Sbjct: 197 DDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDE---EEDDEDEDDDDDEDD 253
Query: 351 VSQAEKDLLHSEGSENEGPVSSS 373
++D E E E PV +
Sbjct: 254 EDDDDEDDEEEEEEEEEEPVKEA 276
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 51.2 bits (121), Expect = 2e-06
Identities = 48/192 (25%), Positives = 77/192 (40%), Gaps = 29/192 (15%)
Query: 235 EDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQ 294
E A A E ++ F + + E TT +A+S K K +
Sbjct: 200 EAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEE 259
Query: 295 HCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQA 354
EE+EEE+EEEE+E + +E+E ++ EE EE + EE + +A
Sbjct: 260 EDEEEEEEEEEEEEDE------------EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEA 307
Query: 355 EKDLLHSEGSENEGPVSSSSSDCRETEELVGSNS-------SKTGEILSESSMENDDEA- 406
D++ E +S + ++ EL G S S E+ S+ + D +
Sbjct: 308 APDVIFQE--------DTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSR 359
Query: 407 -TEVTDEPMEQD 417
+ VTDE QD
Sbjct: 360 KSTVTDESEMQD 371
Score = 33.9 bits (76), Expect = 0.28
Identities = 26/135 (19%), Positives = 52/135 (38%), Gaps = 17/135 (12%)
Query: 187 PMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVK 246
P + SK+ + +EE++ + E E + + +E+ E E E +
Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296
Query: 247 RLRFDKEGE-------VRETASQTTSSEISSVMVGETEASS----------SSQDKDKDS 289
++E E +E S T++ + + E+ + S DKD+D+
Sbjct: 297 EEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDT 356
Query: 290 RCTRQHCTEEDEEED 304
+ T+E E +D
Sbjct: 357 HSRKSTVTDESEMQD 371
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 50.4 bits (119), Expect = 3e-06
Identities = 47/228 (20%), Positives = 88/228 (38%), Gaps = 15/228 (6%)
Query: 195 ESTDSKEANLQQNEEK-NHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKE 253
E +EA + + EEK + E E + H E E E + + + +E
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 468
Query: 254 GEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFM 313
++RE E + + + ++ + RQ D+EE E+EE
Sbjct: 469 EKIREQEEIWRQKE---------KMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMW 519
Query: 314 TSREMIPERKNQEKESDDALTVNEE-TSEENNQMEESDVSQAEKDLLHSEGS---ENEGP 369
E I E++ + +E ++ + EE E+ +M E + E++ + + E E
Sbjct: 520 RQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK 579
Query: 370 VSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
+ RE EE + K E E E +++ E ++ EQ+
Sbjct: 580 IREQKEKIREQEEKIWEQEEKIRE-QEEMMQEQEEKMWEQEEKMCEQE 626
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/219 (18%), Positives = 82/219 (37%), Gaps = 9/219 (4%)
Query: 200 KEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKR----LRFDKEGE 255
+E +Q+ EEK + + + K ++ + E E R + ++KE +
Sbjct: 305 QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
Query: 256 VRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTS 315
+R E + E E Q+K ++ RQ + E+E +E+E
Sbjct: 365 MRRLEEMMWEKEEK---IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 421
Query: 316 REMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSS 375
E I E++ + +E + + EE E ++ E + Q ++++ E E
Sbjct: 422 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 481
Query: 376 DCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPM 414
+ +E + K E M + +E +E M
Sbjct: 482 EKMHEQEKIRKQEEKVWR--QEEKMHDQEEKIREQEEKM 518
Score = 35.4 bits (80), Expect = 0.097
Identities = 34/173 (19%), Positives = 68/173 (39%), Gaps = 19/173 (10%)
Query: 200 KEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRF---DKEGEV 256
++ + + +EK H + E + H E+ + + ++ R ++E ++
Sbjct: 473 EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI 532
Query: 257 RETASQTTSSEI----SSVMVGETEASSSSQDK---------DKDSRCTRQHCTEEDEEE 303
RE + E +GE E Q+K +++ + Q ++EE
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
Query: 304 DEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEK 356
E+EE EM+ E++ + E ++ + EE +E EE Q EK
Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE---QEEKMRRQEEK 642
Score = 35.0 bits (79), Expect = 0.13
Identities = 34/172 (19%), Positives = 67/172 (38%), Gaps = 12/172 (6%)
Query: 200 KEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRET 259
+E + EEK + + + K +++ E E+ + + +K GE E
Sbjct: 500 QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 559
Query: 260 ASQTTSSEISSVMVGETEASSSSQD---KDKDSRCTRQHCTEEDEEEDEEEEEESFMTSR 316
+ + E E Q ++++ + Q ++EE +E+EE
Sbjct: 560 MQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619
Query: 317 EMIPERKNQEKESDDALTVNEETSEENNQMEESDV---SQAEKDLLHSEGSE 365
E + E++ + +E ++ + EE +M E +V Q EK H E E
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEE------KMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 30.8 bits (68), Expect = 2.4
Identities = 26/159 (16%), Positives = 65/159 (40%), Gaps = 15/159 (9%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
E +E +++ EEK + + + + K +++ + + +++ ++E
Sbjct: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIR----EQEE 578
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEE--DEEEDEEEEEESF 312
++RE + E E ++K ++ Q E+ ++EE E+EE
Sbjct: 579 KIREQKEKIREQE---------EKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 629
Query: 313 MTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDV 351
E + ++ + E + L EE +E+ + E+ +
Sbjct: 630 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 29.6 bits (65), Expect = 5.3
Identities = 37/230 (16%), Positives = 91/230 (39%), Gaps = 30/230 (13%)
Query: 205 QQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRF--DKEGEVRETASQ 262
Q+ + + + T E + S+ +N DE+ E ++L+ ++ E++ +
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
Query: 263 TTSS-EISSVMVGETEASSSSQDKDKDSRCTR---QHCTEEDE---------EEDEEEEE 309
E + +++ + + + + K+ + Q EE+E EE +E
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 306
Query: 310 ESFMTSREMIPERKNQEKESDDALTVNEETSEENNQM--EESDVSQAEKDLLHSEGSENE 367
E E I E++ + +E ++ + EE +M E+ + + +++++ +
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK----- 361
Query: 368 GPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD 417
R EE++ K E+ E M ++ E ++ E++
Sbjct: 362 ------EEKMRRLEEMMWEKEEKIREL--EEKMHEQEKIREQEEKRQEEE 403
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 50.4 bits (119), Expect = 3e-06
Identities = 45/217 (20%), Positives = 85/217 (39%), Gaps = 13/217 (5%)
Query: 205 QQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTT 264
QQ EEK + + + K ++ E + + + ++KE ++R
Sbjct: 284 QQQEEKMWRQEEKIQEREEKIQEQEEKIREQ---EEKMRRQEEMMWEKEEKMRRQEEMMW 340
Query: 265 SSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKN 324
E + E E Q+K ++ RQ + E+E +E+E E I E++
Sbjct: 341 EKEEK---IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 325 QEKESDDALTVNEE---TSEENNQMEESDVSQAEKDLLHSEGS--ENEGPVSSSSSDCRE 379
+ +E ++ + EE EE +E ++ + E+ + E E E + RE
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 380 TEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQ 416
EE++ K GE E M + + +E M +
Sbjct: 458 QEEMMQEQEEKMGE--QEGKMCEQEAKMQEQEEKMRR 492
Score = 42.7 bits (99), Expect = 6e-04
Identities = 53/262 (20%), Positives = 105/262 (40%), Gaps = 33/262 (12%)
Query: 177 LNRPKVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDED 236
L + + +LS + N + + + KE N + E+ +S SE +++ V LK K
Sbjct: 186 LTKERDALSLELYRNTITDE-ELKEKNAKLQEKLQLVESEKSEIQLN-VKELKRK----- 238
Query: 237 AVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHC 296
+E + + + E + Q+ S+++ + V E E + + ++ ++
Sbjct: 239 -LERAKLLLPQQQLQAEADHLGKELQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEEK 296
Query: 297 TEEDEEEDEE------EEEESFMTSREMIPERKNQEKESDDALTVNEE------------ 338
+E EE+ +E E+EE EM+ E++ + + ++ + EE
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 356
Query: 339 ----TSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCRETEELVGSNSSKTGEI 394
EE Q EE Q ++ ++ E + RE EE++ K GE
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGE- 415
Query: 395 LSESSMENDDEATEVTDEPMEQ 416
E M +E + +E M +
Sbjct: 416 -QEEKMWEQEEEMQEQEEKMRR 436
Score = 41.6 bits (96), Expect = 0.001
Identities = 45/233 (19%), Positives = 94/233 (40%), Gaps = 18/233 (7%)
Query: 195 ESTDSKEANLQQNEEK--NHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRL--RF 250
E +E +Q+ EEK + + E+ K + +E E E +++ L +
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKIRELEEKM 353
Query: 251 DKEGEVRETASQTTSSEISSVMVGETEASSSSQDK--DKDSRCTRQHCTEEDEEEDEEEE 308
++ ++RE + E + E E + K ++ + Q ++EE +E+
Sbjct: 354 HEQEKIREQEEKRQEEE----KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQ 409
Query: 309 EESFMTSREMIPERKNQEKESDDALTVNEETSEENNQM---EESDVSQAEKDLLHSEG-- 363
EE E + E++ + +E ++ + EE E + +E + + E+ + E
Sbjct: 410 EEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469
Query: 364 SENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQ 416
E EG + + +E EE + K E E + +E +E M++
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIRE--QEKKIREQEEKIREQEEMMQE 520
Score = 40.8 bits (94), Expect = 0.002
Identities = 40/181 (22%), Positives = 75/181 (41%), Gaps = 16/181 (8%)
Query: 195 ESTDSKEANLQQNEEK--NHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDK 252
E +E +Q+ EEK + + E K + +E E E K++R ++
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE----KKIR-EQ 451
Query: 253 EGEVRETASQTTSSEISSVMVGETEASSSSQD---KDKDSRCTRQHCTEEDEEEDEEEEE 309
E ++RE E +GE E Q+ ++++ + RQ ++E+ E+E
Sbjct: 452 EEKIREQEEMMQEQEEK---MGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE 508
Query: 310 ESFMTSREMIPERKNQEKESDDALTVNEE---TSEENNQMEESDVSQAEKDLLHSEGSEN 366
E EM+ E++ + E ++ + EE EE + +E + + E L E
Sbjct: 509 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Query: 367 E 367
E
Sbjct: 569 E 569
Score = 35.8 bits (81), Expect = 0.074
Identities = 33/165 (20%), Positives = 65/165 (39%), Gaps = 15/165 (9%)
Query: 200 KEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDK----EGE 255
+E +++ EEK + + + + K +++ E E R + +K E +
Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK 447
Query: 256 VRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMTS 315
+RE + E M+ E E Q+ + Q +++EE +EE
Sbjct: 448 IREQEEKIREQE---EMMQEQEEKMGEQE----GKMCEQEAKMQEQEEKMRRQEEKIREQ 500
Query: 316 REMIPERKNQEKESDDALTVNEETSEENNQ----MEESDVSQAEK 356
+ I E++ + +E ++ + EE E + EE Q EK
Sbjct: 501 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
Score = 28.9 bits (63), Expect = 9.0
Identities = 26/149 (17%), Positives = 57/149 (38%), Gaps = 17/149 (11%)
Query: 195 ESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEAEGHEVKRLRFDKEG 254
E +E +++ EEK + + + + K +++A E E R + +K
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK-- 496
Query: 255 EVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEEDEEEDEEEEEESFMT 314
+RE + E + ++++ Q ++EE E+EE
Sbjct: 497 -IREQEKKIREQE--------------EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
Query: 315 SREMIPERKNQEKESDDALTVNEETSEEN 343
E + ++ + +E + L EE +E+
Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.123 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,366,885
Number of Sequences: 37866
Number of extensions: 913945
Number of successful extensions: 18094
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 437
Number of HSP's successfully gapped in prelim test: 982
Number of HSP's that attempted gapping in prelim test: 6842
Number of HSP's gapped (non-prelim): 5229
length of query: 417
length of database: 18,247,518
effective HSP length: 105
effective length of query: 312
effective length of database: 14,271,588
effective search space: 4452735456
effective search space used: 4452735456
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.