Search of human proteins with 26667191

Search of human proteins with 26667191

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|26667191 calcium/calmodulin-dependent protein kinase II
gamma isoform 4 [Homo sapiens]
         (495 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|26667191 calcium/calmodulin-dependent protein kinase II gamma...  1016   0.0  
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma...  1008   0.0  
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma...  1003   0.0  
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma...   995   0.0  
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma...   983   0.0  
gi|26051208 calcium/calmodulin-dependent protein kinase II beta ...   914   0.0  
gi|26051210 calcium/calmodulin-dependent protein kinase II beta ...   908   0.0  
gi|26051206 calcium/calmodulin-dependent protein kinase II beta ...   899   0.0  
gi|26051212 calcium/calmodulin-dependent protein kinase II beta ...   897   0.0  
gi|26051216 calcium/calmodulin-dependent protein kinase II beta ...   894   0.0  
gi|212549753 calcium/calmodulin-dependent protein kinase II delt...   893   0.0  
gi|212549756 calcium/calmodulin-dependent protein kinase II delt...   870   0.0  
gi|26667183 calcium/calmodulin-dependent protein kinase II delta...   870   0.0  
gi|26667186 calcium/calmodulin-dependent protein kinase II delta...   870   0.0  
gi|26667180 calcium/calmodulin-dependent protein kinase II delta...   870   0.0  
gi|26667189 calcium/calmodulin-dependent protein kinase II delta...   870   0.0  
gi|26051214 calcium/calmodulin-dependent protein kinase II beta ...   844   0.0  
gi|26051218 calcium/calmodulin-dependent protein kinase II beta ...   841   0.0  
gi|25952114 calcium/calmodulin-dependent protein kinase II alpha...   834   0.0  
gi|25952118 calcium/calmodulin-dependent protein kinase II alpha...   832   0.0  
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ...   634   0.0  
gi|186700629 calcium/calmodulin-dependent serine protein kinase ...   275   5e-74
gi|186700627 calcium/calmodulin-dependent serine protein kinase ...   275   5e-74
gi|186972120 calcium/calmodulin-dependent serine protein kinase ...   275   5e-74
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ...   241   8e-64
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor...   236   5e-62
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo...   236   5e-62
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s...   233   4e-61
gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca...   226   5e-59
gi|209364619 pregnancy upregulated non-ubiquitously expressed Ca...   226   5e-59

>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
           isoform 4 [Homo sapiens]
          Length = 495

 Score = 1016 bits (2627), Expect = 0.0
 Identities = 495/495 (100%), Positives = 495/495 (100%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360
           KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360

Query: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420
           KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL
Sbjct: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420

Query: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480
           SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL
Sbjct: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480

Query: 481 NVHYHCSGAPAAPLQ 495
           NVHYHCSGAPAAPLQ
Sbjct: 481 NVHYHCSGAPAAPLQ 495


>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
           isoform 6 [Homo sapiens]
          Length = 504

 Score = 1008 bits (2607), Expect = 0.0
 Identities = 495/504 (98%), Positives = 495/504 (98%), Gaps = 9/504 (1%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVK---------EPQTTVVHNATDGIKGSTESC 351
           KGAILTTMLVSRNFSAAKSLLNKKSDGGVK         EPQTTVVHNATDGIKGSTESC
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLEPQTTVVHNATDGIKGSTESC 360

Query: 352 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 411
           NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF
Sbjct: 361 NTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDF 420

Query: 412 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 471
           HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV
Sbjct: 421 HKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRV 480

Query: 472 WHRRDGKWLNVHYHCSGAPAAPLQ 495
           WHRRDGKWLNVHYHCSGAPAAPLQ
Sbjct: 481 WHRRDGKWLNVHYHCSGAPAAPLQ 504


>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
           isoform 3 [Homo sapiens]
          Length = 518

 Score = 1003 bits (2593), Expect = 0.0
 Identities = 495/518 (95%), Positives = 495/518 (95%), Gaps = 23/518 (4%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVK-----------------------EPQTTVV 337
           KGAILTTMLVSRNFSAAKSLLNKKSDGGVK                       EPQTTVV
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360

Query: 338 HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSF 397
           HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSF
Sbjct: 361 HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSF 420

Query: 398 EPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 457
           EPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG
Sbjct: 421 EPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 480

Query: 458 QGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 495
           QGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ
Sbjct: 481 QGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 518


>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
           isoform 2 [Homo sapiens]
          Length = 527

 Score =  995 bits (2573), Expect = 0.0
 Identities = 495/527 (93%), Positives = 495/527 (93%), Gaps = 32/527 (6%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300

Query: 301 KGAILTTMLVSRNFS---------------------AAKSLLNKKSDGGVK--------- 330
           KGAILTTMLVSRNFS                     AAKSLLNKKSDGGVK         
Sbjct: 301 KGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVH 360

Query: 331 --EPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTK 388
             EPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTK
Sbjct: 361 LMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTK 420

Query: 389 ICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAY 448
           ICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAY
Sbjct: 421 ICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAY 480

Query: 449 IRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 495
           IRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ
Sbjct: 481 IRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 527


>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
           isoform 1 [Homo sapiens]
          Length = 556

 Score =  983 bits (2541), Expect = 0.0
 Identities = 494/556 (88%), Positives = 495/556 (89%), Gaps = 61/556 (10%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
Sbjct: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVK-----------------------EPQTTVV 337
           KGAILTTMLVSRNFSAAKSLLNKKSDGGVK                       EPQTTVV
Sbjct: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNNKNSLVSPAQEPAPLQTAMEPQTTVV 360

Query: 338 HNATDGIKGSTESCNTTTEDEDLK------------------------------------ 361
           HNATDGIKGSTESCNTTTEDEDLK                                    
Sbjct: 361 HNATDGIKGSTESCNTTTEDEDLKAAPLRTGNGSSVPEGRSSRDRTAPSAGMQPQPSLCS 420

Query: 362 --VRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 419
             +RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL
Sbjct: 421 SAMRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENL 480

Query: 420 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 479
           LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW
Sbjct: 481 LSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 540

Query: 480 LNVHYHCSGAPAAPLQ 495
           LNVHYHCSGAPAAPLQ
Sbjct: 541 LNVHYHCSGAPAAPLQ 556


>gi|26051208 calcium/calmodulin-dependent protein kinase II beta
           isoform 3 [Homo sapiens]
          Length = 518

 Score =  914 bits (2362), Expect = 0.0
 Identities = 447/518 (86%), Positives = 467/518 (90%), Gaps = 23/518 (4%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK  +  EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LE+V H HQ  +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDG-----------------------GVKEPQTTVV 337
           KGAILTTML +RNFSAAKSLLNKK+DG                          EPQTTV+
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 360

Query: 338 HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSF 397
           HN  DGIK S++S NTT EDED K RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSF
Sbjct: 361 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 420

Query: 398 EPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 457
           EPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG
Sbjct: 421 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 480

Query: 458 QGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 495
           QGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 481 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 518


>gi|26051210 calcium/calmodulin-dependent protein kinase II beta
           isoform 4 [Homo sapiens]
          Length = 517

 Score =  908 bits (2346), Expect = 0.0
 Identities = 446/518 (86%), Positives = 466/518 (89%), Gaps = 24/518 (4%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK  +  EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LE+V H HQ  +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDG-----------------------GVKEPQTTVV 337
           KGAILTTML +RNFS AKSLLNKK+DG                          EPQTTV+
Sbjct: 301 KGAILTTMLATRNFS-AKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 359

Query: 338 HNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSF 397
           HN  DGIK S++S NTT EDED K RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSF
Sbjct: 360 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 419

Query: 398 EPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 457
           EPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG
Sbjct: 420 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 479

Query: 458 QGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 495
           QGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 480 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 517


>gi|26051206 calcium/calmodulin-dependent protein kinase II beta
           isoform 2 [Homo sapiens]
          Length = 542

 Score =  899 bits (2323), Expect = 0.0
 Identities = 446/542 (82%), Positives = 466/542 (85%), Gaps = 47/542 (8%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK  +  EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LE+V H HQ  +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDG--------- 327
           KGAILTTML +RNFS                         AKSLLNKK+DG         
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360

Query: 328 --------------GVKEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQ 373
                            EPQTTV+HN  DGIK S++S NTT EDED K RKQEIIK TEQ
Sbjct: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 420

Query: 374 LIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILN 433
           LIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+KNSKPIHTTILN
Sbjct: 421 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 480

Query: 434 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAP 493
           PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP AP
Sbjct: 481 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 540

Query: 494 LQ 495
           LQ
Sbjct: 541 LQ 542


>gi|26051212 calcium/calmodulin-dependent protein kinase II beta
           isoform 5 [Homo sapiens]
          Length = 503

 Score =  897 bits (2317), Expect = 0.0
 Identities = 439/503 (87%), Positives = 460/503 (91%), Gaps = 8/503 (1%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK  +  EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LE+V H HQ  +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKG--------STESCN 352
           KGAILTTML +RNFSAAKSLLNKK+DG   +  +T    A    KG        S++S N
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN 360

Query: 353 TTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFH 412
           TT EDED K RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH
Sbjct: 361 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 420

Query: 413 KFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 472
           +FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW
Sbjct: 421 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 480

Query: 473 HRRDGKWLNVHYHCSGAPAAPLQ 495
           HRRDGKW NVH+HCSGAP APLQ
Sbjct: 481 HRRDGKWQNVHFHCSGAPVAPLQ 503


>gi|26051216 calcium/calmodulin-dependent protein kinase II beta
           isoform 7 [Homo sapiens]
          Length = 479

 Score =  894 bits (2311), Expect = 0.0
 Identities = 436/495 (88%), Positives = 456/495 (92%), Gaps = 16/495 (3%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK  +  EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LE+V H HQ  +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360
           KGAILTTML +RNFSAAKSLLNKK+                DG+K S++S NTT EDED 
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKA----------------DGVKESSDSANTTIEDEDA 344

Query: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420
           K RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL
Sbjct: 345 KARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLL 404

Query: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480
           +KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 
Sbjct: 405 AKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQ 464

Query: 481 NVHYHCSGAPAAPLQ 495
           NVH+HCSGAP APLQ
Sbjct: 465 NVHFHCSGAPVAPLQ 479


>gi|212549753 calcium/calmodulin-dependent protein kinase II delta
           isoform 5 [Homo sapiens]
          Length = 492

 Score =  893 bits (2307), Expect = 0.0
 Identities = 432/495 (87%), Positives = 463/495 (93%), Gaps = 3/495 (0%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K  + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360
           KGAILTTML +RNFSAAKSLL K    GVKEPQTTV+HN  DG K STES NTT EDED+
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPD--GVKEPQTTVIHN-PDGNKESTESSNTTIEDEDV 357

Query: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420
           K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN L
Sbjct: 358 KARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENAL 417

Query: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480
           SK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW 
Sbjct: 418 SKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQ 477

Query: 481 NVHYHCSGAPAAPLQ 495
           NVH+H SG+P  P++
Sbjct: 478 NVHFHRSGSPTVPIK 492


>gi|212549756 calcium/calmodulin-dependent protein kinase II delta
           isoform 4 [Homo sapiens]
          Length = 489

 Score =  870 bits (2248), Expect = 0.0
 Identities = 423/495 (85%), Positives = 456/495 (92%), Gaps = 6/495 (1%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K  + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360
           KGAILTTML +RNFSAAKSLL KK DG  K   ++ V      +  STES NTT EDED+
Sbjct: 301 KGAILTTMLATRNFSAAKSLL-KKPDGVKKRKSSSSVQ-----MMESTESSNTTIEDEDV 354

Query: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420
           K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN L
Sbjct: 355 KARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENAL 414

Query: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480
           SK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW 
Sbjct: 415 SKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQ 474

Query: 481 NVHYHCSGAPAAPLQ 495
           NVH+H SG+P  P++
Sbjct: 475 NVHFHRSGSPTVPIK 489


>gi|26667183 calcium/calmodulin-dependent protein kinase II delta
           isoform 1 [Homo sapiens]
          Length = 478

 Score =  870 bits (2248), Expect = 0.0
 Identities = 421/495 (85%), Positives = 452/495 (91%), Gaps = 17/495 (3%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K  + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360
           KGAILTTML +RNFSAAKSLL K                  DG+K STES NTT EDED+
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK-----------------PDGVKESTESSNTTIEDEDV 343

Query: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420
           K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN L
Sbjct: 344 KARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENAL 403

Query: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480
           SK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW 
Sbjct: 404 SKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQ 463

Query: 481 NVHYHCSGAPAAPLQ 495
           NVH+H SG+P  P++
Sbjct: 464 NVHFHRSGSPTVPIK 478


>gi|26667186 calcium/calmodulin-dependent protein kinase II delta
           isoform 1 [Homo sapiens]
          Length = 478

 Score =  870 bits (2248), Expect = 0.0
 Identities = 421/495 (85%), Positives = 452/495 (91%), Gaps = 17/495 (3%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K  + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360
           KGAILTTML +RNFSAAKSLL K                  DG+K STES NTT EDED+
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK-----------------PDGVKESTESSNTTIEDEDV 343

Query: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420
           K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN L
Sbjct: 344 KARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENAL 403

Query: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480
           SK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW 
Sbjct: 404 SKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQ 463

Query: 481 NVHYHCSGAPAAPLQ 495
           NVH+H SG+P  P++
Sbjct: 464 NVHFHRSGSPTVPIK 478


>gi|26667180 calcium/calmodulin-dependent protein kinase II delta
           isoform 3 [Homo sapiens]
          Length = 499

 Score =  870 bits (2248), Expect = 0.0
 Identities = 421/495 (85%), Positives = 452/495 (91%), Gaps = 17/495 (3%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K  + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360
           KGAILTTML +RNFSAAKSLL K                  DG+K STES NTT EDED+
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK-----------------PDGVKESTESSNTTIEDEDV 343

Query: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420
           K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN L
Sbjct: 344 KARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENAL 403

Query: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480
           SK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW 
Sbjct: 404 SKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQ 463

Query: 481 NVHYHCSGAPAAPLQ 495
           NVH+H SG+P  P++
Sbjct: 464 NVHFHRSGSPTVPIK 478


>gi|26667189 calcium/calmodulin-dependent protein kinase II delta
           isoform 2 [Homo sapiens]
          Length = 478

 Score =  870 bits (2247), Expect = 0.0
 Identities = 421/494 (85%), Positives = 451/494 (91%), Gaps = 17/494 (3%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MA+T TCTRFTD+YQLFEELGKGAFSVVRRC+K  + QEYAAKIINTKKLSARDHQKLER
Sbjct: 1   MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LESVNH H + IVHRDLKPENLLLASK KGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAK+LIN+MLTINPAKRITA +ALKHPW+CQRSTVASMMHRQETV+CL+KFNARRKL
Sbjct: 241 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360
           KGAILTTML +RNFSAAKSLL K                  DG+K STES NTT EDED+
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKK-----------------PDGVKESTESSNTTIEDEDV 343

Query: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420
           K RKQEIIK+TEQLIEAINNGDFEAYTKICDPGLT+FEPEALGNLVEGMDFH+FYFEN L
Sbjct: 344 KARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENAL 403

Query: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480
           SK++KPIHT ILNPHVH++G+DAACIAYIRLTQY+DG G P+T QSEETRVWHRRDGKW 
Sbjct: 404 SKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQ 463

Query: 481 NVHYHCSGAPAAPL 494
           NVH+H SG+P  P+
Sbjct: 464 NVHFHRSGSPTVPI 477


>gi|26051214 calcium/calmodulin-dependent protein kinase II beta
           isoform 6 [Homo sapiens]
          Length = 492

 Score =  844 bits (2180), Expect = 0.0
 Identities = 423/519 (81%), Positives = 442/519 (85%), Gaps = 51/519 (9%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK  +  EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LE+V H HQ  +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDGGVKEPQTTV 336
           KGAILTTML +RNFS                         AKSLLNKK+D GVKEPQTTV
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKAD-GVKEPQTTV 359

Query: 337 VHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTS 396
           +HN  DGIK S++S NTT EDED K RKQEIIK TEQLIEA+NNGDFEAY          
Sbjct: 360 IHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYA--------- 410

Query: 397 FEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID 456
                            FYFENLL+KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID
Sbjct: 411 -----------------FYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYID 453

Query: 457 GQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ 495
           GQGRPRTSQSEETRVWHRRDGKW NVH+HCSGAP APLQ
Sbjct: 454 GQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 492


>gi|26051218 calcium/calmodulin-dependent protein kinase II beta
           isoform 8 [Homo sapiens]
          Length = 449

 Score =  841 bits (2173), Expect = 0.0
 Identities = 415/495 (83%), Positives = 431/495 (87%), Gaps = 46/495 (9%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK  +  EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LE+V H HQ  +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDL 360
           KGAILTTML +RNFSA                                            
Sbjct: 301 KGAILTTMLATRNFSA-------------------------------------------- 316

Query: 361 KVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLL 420
             RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL
Sbjct: 317 --RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLL 374

Query: 421 SKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWL 480
           +KNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW 
Sbjct: 375 AKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQ 434

Query: 481 NVHYHCSGAPAAPLQ 495
           NVH+HCSGAP APLQ
Sbjct: 435 NVHFHCSGAPVAPLQ 449


>gi|25952114 calcium/calmodulin-dependent protein kinase II alpha
           isoform 1 [Homo sapiens]
          Length = 489

 Score =  834 bits (2155), Expect = 0.0
 Identities = 402/488 (82%), Positives = 444/488 (90%), Gaps = 5/488 (1%)

Query: 4   TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREAR 63
           T TCTRFT++YQLFEELGKGAFSVVRRCVK  + QEYAAKIINTKKLSARDHQKLEREAR
Sbjct: 3   TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62

Query: 64  ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILES 123
           ICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCI QILE+
Sbjct: 63  ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122

Query: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183
           V H HQ  +VHRDLKPENLLLASK KGAAVKLADFGLAIEV+GEQQAWFGFAGTPGYLSP
Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182

Query: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
           EVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242

Query: 244 EAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGA 303
           EAK+LIN+MLTINP+KRITA +ALKHPW+  RSTVAS MHRQETV+CL+KFNARRKLKGA
Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302

Query: 304 ILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVR 363
           ILTTML +RNFS  KS  NKKSDG  K   ++ V      +  S+ES NTT EDED KVR
Sbjct: 303 ILTTMLATRNFSGGKSGGNKKSDGVKKRKSSSSVQ-----LMESSESTNTTIEDEDTKVR 357

Query: 364 KQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKN 423
           KQEIIK+TEQLIEAI+NGDFE+YTK+CDPG+T+FEPEALGNLVEG+DFH+FYFENL S+N
Sbjct: 358 KQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRN 417

Query: 424 SKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVH 483
           SKP+HTTILNPH+H++G+++ACIAYIR+TQY+D  G PRT+QSEETRVWHRRDGKW  VH
Sbjct: 418 SKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVH 477

Query: 484 YHCSGAPA 491
           +H SGAP+
Sbjct: 478 FHRSGAPS 485


>gi|25952118 calcium/calmodulin-dependent protein kinase II alpha
           isoform 2 [Homo sapiens]
          Length = 478

 Score =  832 bits (2148), Expect = 0.0
 Identities = 401/488 (82%), Positives = 441/488 (90%), Gaps = 16/488 (3%)

Query: 4   TATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREAR 63
           T TCTRFT++YQLFEELGKGAFSVVRRCVK  + QEYAAKIINTKKLSARDHQKLEREAR
Sbjct: 3   TITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREAR 62

Query: 64  ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILES 123
           ICRLLKHPNIVRLHDSISEEG HYL+FDLVTGGELFEDIVAREYYSEADASHCI QILE+
Sbjct: 63  ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEA 122

Query: 124 VNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 183
           V H HQ  +VHRDLKPENLLLASK KGAAVKLADFGLAIEV+GEQQAWFGFAGTPGYLSP
Sbjct: 123 VLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSP 182

Query: 184 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 243
           EVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQH+LYQQIKAGAYDFPSPEWDTVTP
Sbjct: 183 EVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTP 242

Query: 244 EAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGA 303
           EAK+LIN+MLTINP+KRITA +ALKHPW+  RSTVAS MHRQETV+CL+KFNARRKLKGA
Sbjct: 243 EAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGA 302

Query: 304 ILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVR 363
           ILTTML +RNFS  KS  NKKS                DG+K S+ES NTT EDED KVR
Sbjct: 303 ILTTMLATRNFSGGKSGGNKKS----------------DGVKESSESTNTTIEDEDTKVR 346

Query: 364 KQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKN 423
           KQEIIK+TEQLIEAI+NGDFE+YTK+CDPG+T+FEPEALGNLVEG+DFH+FYFENL S+N
Sbjct: 347 KQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRN 406

Query: 424 SKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVH 483
           SKP+HTTILNPH+H++G+++ACIAYIR+TQY+D  G PRT+QSEETRVWHRRDGKW  VH
Sbjct: 407 SKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVH 466

Query: 484 YHCSGAPA 491
           +H SGAP+
Sbjct: 467 FHRSGAPS 474


>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
           isoform 1 [Homo sapiens]
          Length = 666

 Score =  634 bits (1635), Expect = 0.0
 Identities = 321/408 (78%), Positives = 337/408 (82%), Gaps = 47/408 (11%)

Query: 1   MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 60
           MATT TCTRFTD+YQL+E++GKGAFSVVRRCVK  +  EYAAKIINTKKLSARDHQKLER
Sbjct: 1   MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 60

Query: 61  EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 120
           EARICRLLKH NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI QI
Sbjct: 61  EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 120

Query: 121 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 180
           LE+V H HQ  +VHRDLKPENLLLASKCKGAAVKLADFGLAIEVQG+QQAWFGFAGTPGY
Sbjct: 121 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 180

Query: 181 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240
           LSPEVLRK+ YGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
Sbjct: 181 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 240

Query: 241 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 300
           VTPEAKNLINQMLTINPAKRITA +ALKHPWVCQRSTVASMMHRQETVECL+KFNARRKL
Sbjct: 241 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 300

Query: 301 KGAILTTMLVSRNFSA------------------------AKSLLNKKSDG--------- 327
           KGAILTTML +RNFS                         AKSLLNKK+DG         
Sbjct: 301 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 360

Query: 328 --------------GVKEPQTTVVHNATDGIKGSTESCNTTTEDEDLK 361
                            EPQTTV+HN  DGIK S++S NTT EDED K
Sbjct: 361 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAK 408



 Score =  269 bits (688), Expect = 4e-72
 Identities = 125/133 (93%), Positives = 129/133 (96%)

Query: 363 RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSK 422
           RKQEIIK TEQLIEA+NNGDFEAY KICDPGLTSFEPEALGNLVEGMDFH+FYFENLL+K
Sbjct: 534 RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAK 593

Query: 423 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNV 482
           NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKW NV
Sbjct: 594 NSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNV 653

Query: 483 HYHCSGAPAAPLQ 495
           H+HCSGAP APLQ
Sbjct: 654 HFHCSGAPVAPLQ 666


>gi|186700629 calcium/calmodulin-dependent serine protein kinase
           isoform 3 [Homo sapiens]
          Length = 897

 Score =  275 bits (704), Expect = 5e-74
 Identities = 141/306 (46%), Positives = 205/306 (66%), Gaps = 8/306 (2%)

Query: 10  FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSAR---DHQKLEREARICR 66
           F D Y+L E +GKG FSVVRRC+ + + Q++A KI++  K ++      + L+REA IC 
Sbjct: 8   FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67

Query: 67  LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIHQILE 122
           +LKHP+IV L ++ S +G  Y+VF+ + G +L  +IV R      YSEA ASH + QILE
Sbjct: 68  MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127

Query: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
           ++ + H ++I+HRD+KP  +LLASK   A VKL  FG+AI++        G  GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187

Query: 183 PEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
           PEV++++PYGKPVD+W CGVIL+ILL G  PF+   + +L++ I  G Y     +W  ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246

Query: 243 PEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKG 302
             AK+L+ +ML ++PA+RIT  +AL HPW+ +R   A  +H  ETVE LRKFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306

Query: 303 AILTTM 308
           A+L  +
Sbjct: 307 AVLAAV 312


>gi|186700627 calcium/calmodulin-dependent serine protein kinase
           isoform 2 [Homo sapiens]
          Length = 898

 Score =  275 bits (704), Expect = 5e-74
 Identities = 141/306 (46%), Positives = 205/306 (66%), Gaps = 8/306 (2%)

Query: 10  FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSAR---DHQKLEREARICR 66
           F D Y+L E +GKG FSVVRRC+ + + Q++A KI++  K ++      + L+REA IC 
Sbjct: 8   FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67

Query: 67  LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIHQILE 122
           +LKHP+IV L ++ S +G  Y+VF+ + G +L  +IV R      YSEA ASH + QILE
Sbjct: 68  MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127

Query: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
           ++ + H ++I+HRD+KP  +LLASK   A VKL  FG+AI++        G  GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187

Query: 183 PEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
           PEV++++PYGKPVD+W CGVIL+ILL G  PF+   + +L++ I  G Y     +W  ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246

Query: 243 PEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKG 302
             AK+L+ +ML ++PA+RIT  +AL HPW+ +R   A  +H  ETVE LRKFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306

Query: 303 AILTTM 308
           A+L  +
Sbjct: 307 AVLAAV 312


>gi|186972120 calcium/calmodulin-dependent serine protein kinase
           isoform 1 [Homo sapiens]
          Length = 921

 Score =  275 bits (704), Expect = 5e-74
 Identities = 141/306 (46%), Positives = 205/306 (66%), Gaps = 8/306 (2%)

Query: 10  FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSAR---DHQKLEREARICR 66
           F D Y+L E +GKG FSVVRRC+ + + Q++A KI++  K ++      + L+REA IC 
Sbjct: 8   FEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICH 67

Query: 67  LLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVARE----YYSEADASHCIHQILE 122
           +LKHP+IV L ++ S +G  Y+VF+ + G +L  +IV R      YSEA ASH + QILE
Sbjct: 68  MLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILE 127

Query: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
           ++ + H ++I+HRD+KP  +LLASK   A VKL  FG+AI++        G  GTP +++
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187

Query: 183 PEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVT 242
           PEV++++PYGKPVD+W CGVIL+ILL G  PF+   + +L++ I  G Y     +W  ++
Sbjct: 188 PEVVKREPYGKPVDVWGCGVILFILLSGCLPFYG-TKERLFEGIIKGKYKMNPRQWSHIS 246

Query: 243 PEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKG 302
             AK+L+ +ML ++PA+RIT  +AL HPW+ +R   A  +H  ETVE LRKFNARRKLKG
Sbjct: 247 ESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKG 306

Query: 303 AILTTM 308
           A+L  +
Sbjct: 307 AVLAAV 312


>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
           sapiens]
          Length = 473

 Score =  241 bits (616), Expect = 8e-64
 Identities = 142/378 (37%), Positives = 222/378 (58%), Gaps = 13/378 (3%)

Query: 11  TDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
           +D +++  ELG+GA S+V RC +K + + YA K++        D + +  E  +   L H
Sbjct: 43  SDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK----KTVDKKIVRTEIGVLLRLSH 98

Query: 71  PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130
           PNI++L +         LV +LVTGGELF+ IV + YYSE DA+  + QILE+V ++H++
Sbjct: 99  PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158

Query: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDP 190
            IVHRDLKPENLL A+    A +K+ADFGL+ ++   Q       GTPGY +PE+LR   
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLS-KIVEHQVLMKTVCGTPGYCAPEILRGCA 217

Query: 191 YGKPVDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
           YG  VD+W+ G+I YILL G+ PF+DE  DQ  ++++I    Y F SP WD V+  AK+L
Sbjct: 218 YGPEVDMWSVGIITYILLCGFEPFYDERGDQF-MFRRILNCEYYFISPWWDEVSLNAKDL 276

Query: 249 INQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTM 308
           + +++ ++P KR+T  QAL+HPWV  ++  A+ +H     + L++FNARRKLK A+   +
Sbjct: 277 VRKLIVLDPKKRLTTFQALQHPWVTGKA--ANFVHMDTAQKKLQEFNARRKLKAAVKAVV 334

Query: 309 LVSRNFSAAKSLLN-KKSDGGVKEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEI 367
             SR  SA+ S  + ++S    ++P  + + +  + +K   E      +     V+  + 
Sbjct: 335 ASSRLGSASSSHGSIQESHKASRDP--SPIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQA 392

Query: 368 IKITEQLIEAINNGDFEA 385
             +  Q +E +   D  A
Sbjct: 393 ELMKVQALEKVKGADINA 410


>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
           [Homo sapiens]
          Length = 357

 Score =  236 bits (601), Expect = 5e-62
 Identities = 123/297 (41%), Positives = 183/297 (61%), Gaps = 3/297 (1%)

Query: 14  YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
           ++  E LG GAFS V    +K + + +A K I  K L  ++   +E E  + R +KH NI
Sbjct: 23  FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81

Query: 74  VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
           V L D        YLV  LV+GGELF+ IV + +Y+E DAS  I Q+L++V ++H+  IV
Sbjct: 82  VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141

Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGK 193
           HRDLKPENLL  S+ + + + ++DFGL+ +++G+        GTPGY++PEVL + PY K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200

Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
            VD W+ GVI YILL GYPPF+DE+  KL++QI    Y+F SP WD ++  AK+ I  ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260

Query: 254 TINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLV 310
             +P KR T +QA +HPW+   + +   +H   + + +RK  A+ K + A   T +V
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQ-IRKNFAKSKWRQAFNATAVV 316


>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
           2 [Homo sapiens]
          Length = 385

 Score =  236 bits (601), Expect = 5e-62
 Identities = 123/297 (41%), Positives = 183/297 (61%), Gaps = 3/297 (1%)

Query: 14  YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
           ++  E LG GAFS V    +K + + +A K I  K L  ++   +E E  + R +KH NI
Sbjct: 23  FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKE-SSIENEIAVLRKIKHENI 81

Query: 74  VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
           V L D        YLV  LV+GGELF+ IV + +Y+E DAS  I Q+L++V ++H+  IV
Sbjct: 82  VALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIV 141

Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGK 193
           HRDLKPENLL  S+ + + + ++DFGL+ +++G+        GTPGY++PEVL + PY K
Sbjct: 142 HRDLKPENLLYYSQDEESKIMISDFGLS-KMEGKGDVMSTACGTPGYVAPEVLAQKPYSK 200

Query: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
            VD W+ GVI YILL GYPPF+DE+  KL++QI    Y+F SP WD ++  AK+ I  ++
Sbjct: 201 AVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLM 260

Query: 254 TINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLV 310
             +P KR T +QA +HPW+   + +   +H   + + +RK  A+ K + A   T +V
Sbjct: 261 EKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQ-IRKNFAKSKWRQAFNATAVV 316


>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
           sapiens]
          Length = 370

 Score =  233 bits (593), Expect = 4e-61
 Identities = 125/299 (41%), Positives = 179/299 (59%), Gaps = 3/299 (1%)

Query: 12  DDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHP 71
           D Y   + LG GAFS V     K + +  A K I  + L  ++   +E E  +   +KHP
Sbjct: 18  DIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGS-MENEIAVLHKIKHP 76

Query: 72  NIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHD 131
           NIV L D     G  YL+  LV+GGELF+ IV + +Y+E DAS  I Q+L++V ++H   
Sbjct: 77  NIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLG 136

Query: 132 IVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPY 191
           IVHRDLKPENLL  S  + + + ++DFGL+ +++          GTPGY++PEVL + PY
Sbjct: 137 IVHRDLKPENLLYYSLDEDSKIMISDFGLS-KMEDPGSVLSTACGTPGYVAPEVLAQKPY 195

Query: 192 GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQ 251
            K VD W+ GVI YILL GYPPF+DE+  KL++QI    Y+F SP WD ++  AK+ I  
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRH 255

Query: 252 MLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLV 310
           ++  +P KR T +QAL+HPW+   + +   +H Q   E ++K  A+ K K A   T +V
Sbjct: 256 LMEKDPEKRFTCEQALQHPWIAGDTALDKNIH-QSVSEQIKKNFAKSKWKQAFNATAVV 313


>gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM
           kinase isoform b [Homo sapiens]
          Length = 360

 Score =  226 bits (575), Expect = 5e-59
 Identities = 119/260 (45%), Positives = 162/260 (62%), Gaps = 5/260 (1%)

Query: 14  YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
           Y++ E LG GAFS V    ++ S    A K I  K L  ++   +E E  + R + HPNI
Sbjct: 32  YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKE-ALVENEIAVLRRISHPNI 90

Query: 74  VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
           V L D        YL  +LVTGGELF+ I+ R  Y+E DASH + Q+L +V+++H   IV
Sbjct: 91  VALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIV 150

Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GTPGYLSPEVLRKDPYG 192
           HRDLKPENLL A+  + + + ++DFGL+    G      G A GTPGY++PE+L + PYG
Sbjct: 151 HRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNM---LGTACGTPGYVAPELLEQKPYG 207

Query: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
           K VD+WA GVI YILL GYPPF+DE   +L+ QI   +Y+F SP WD ++  AK+ I  +
Sbjct: 208 KAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHL 267

Query: 253 LTINPAKRITADQALKHPWV 272
           L  +P KR T  QAL+H W+
Sbjct: 268 LERDPQKRFTCQQALRHLWI 287


>gi|209364619 pregnancy upregulated non-ubiquitously expressed CaM
           kinase isoform a [Homo sapiens]
          Length = 426

 Score =  226 bits (575), Expect = 5e-59
 Identities = 119/260 (45%), Positives = 162/260 (62%), Gaps = 5/260 (1%)

Query: 14  YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI 73
           Y++ E LG GAFS V    ++ S    A K I  K L  ++   +E E  + R + HPNI
Sbjct: 98  YEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKE-ALVENEIAVLRRISHPNI 156

Query: 74  VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV 133
           V L D        YL  +LVTGGELF+ I+ R  Y+E DASH + Q+L +V+++H   IV
Sbjct: 157 VALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIV 216

Query: 134 HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GTPGYLSPEVLRKDPYG 192
           HRDLKPENLL A+  + + + ++DFGL+    G      G A GTPGY++PE+L + PYG
Sbjct: 217 HRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNM---LGTACGTPGYVAPELLEQKPYG 273

Query: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
           K VD+WA GVI YILL GYPPF+DE   +L+ QI   +Y+F SP WD ++  AK+ I  +
Sbjct: 274 KAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHL 333

Query: 253 LTINPAKRITADQALKHPWV 272
           L  +P KR T  QAL+H W+
Sbjct: 334 LERDPQKRFTCQQALRHLWI 353


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,414,249
Number of Sequences: 37866
Number of extensions: 881908
Number of successful extensions: 4688
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 596
Number of HSP's successfully gapped in prelim test: 207
Number of HSP's that attempted gapping in prelim test: 2303
Number of HSP's gapped (non-prelim): 1006
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.