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Search of human proteins with 253795481
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|253795481 plexin B3 isoform 2 [Homo sapiens]
(1932 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|253795481 plexin B3 isoform 2 [Homo sapiens] 3939 0.0
gi|29336063 plexin B3 isoform 1 [Homo sapiens] 3859 0.0
gi|194272180 plexin B1 [Homo sapiens] 1264 0.0
gi|40254442 plexin B1 [Homo sapiens] 1264 0.0
gi|149363636 plexin B2 [Homo sapiens] 1210 0.0
gi|157694524 plexin D1 [Homo sapiens] 967 0.0
gi|113722116 plexin A2 [Homo sapiens] 966 0.0
gi|49355818 plexin A1 [Homo sapiens] 955 0.0
gi|157738645 plexin A4 isoform 1 [Homo sapiens] 927 0.0
gi|59710104 plexin A3 [Homo sapiens] 913 0.0
gi|5032223 plexin C1 [Homo sapiens] 384 e-106
gi|157738643 plexin A4 isoform 2 [Homo sapiens] 120 1e-26
gi|157738647 plexin A4 isoform 3 [Homo sapiens] 112 4e-24
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens] 100 1e-20
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s... 95 8e-19
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens] 91 1e-17
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 62 5e-09
gi|157388902 semaphorin 4C [Homo sapiens] 61 9e-09
gi|21361914 semaphorin B [Homo sapiens] 58 1e-07
gi|147904700 semaphorin 5A [Homo sapiens] 55 9e-07
gi|39777610 semaphorin 4B precursor [Homo sapiens] 54 1e-06
gi|39777608 semaphorin 4B precursor [Homo sapiens] 54 1e-06
gi|19718780 semaphorin 6B precursor [Homo sapiens] 52 4e-06
gi|28872814 semaphorin 4G [Homo sapiens] 52 7e-06
gi|126116589 fibrocystin L [Homo sapiens] 51 1e-05
gi|11991660 sema domain, transmembrane domain (TM), and cytoplas... 49 6e-05
gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 47 1e-04
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 47 1e-04
gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] 47 1e-04
gi|19923279 semaphorin W [Homo sapiens] 46 4e-04
>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
Length = 1932
Score = 3939 bits (10214), Expect = 0.0
Identities = 1932/1932 (100%), Positives = 1932/1932 (100%)
Query: 1 MELTPASSLTCSLLSPRLPGSFPQLRRVPPCSRPWLPKAPVMARWPPFGLCLLLLLLSPP 60
MELTPASSLTCSLLSPRLPGSFPQLRRVPPCSRPWLPKAPVMARWPPFGLCLLLLLLSPP
Sbjct: 1 MELTPASSLTCSLLSPRLPGSFPQLRRVPPCSRPWLPKAPVMARWPPFGLCLLLLLLSPP 60
Query: 61 PLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPD 120
PLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPD
Sbjct: 61 PLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPD 120
Query: 121 CVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQAED 180
CVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQAED
Sbjct: 121 CVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQAED 180
Query: 181 PGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSE 240
PGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSE
Sbjct: 181 PGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSE 240
Query: 241 GLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYV 300
GLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYV
Sbjct: 241 GLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYV 300
Query: 301 EVPLACQGQGLIQAAFLAPGTLLGVFAAGPRGTQAALCAFPMVELGASMEQARRLCYTAG 360
EVPLACQGQGLIQAAFLAPGTLLGVFAAGPRGTQAALCAFPMVELGASMEQARRLCYTAG
Sbjct: 301 EVPLACQGQGLIQAAFLAPGTLLGVFAAGPRGTQAALCAFPMVELGASMEQARRLCYTAG 360
Query: 361 GRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPV 420
GRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPV
Sbjct: 361 GRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPV 420
Query: 421 SAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSH 480
SAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSH
Sbjct: 421 SAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSH 480
Query: 481 LYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLW 540
LYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLW
Sbjct: 481 LYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLW 540
Query: 541 SYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPH 600
SYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPH
Sbjct: 541 SYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPH 600
Query: 601 VACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACV 660
VACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACV
Sbjct: 601 VACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACV 660
Query: 661 GSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGLAGPHLVPVGW 720
GSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGLAGPHLVPVGW
Sbjct: 661 GSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGLAGPHLVPVGW 720
Query: 721 ESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHCQAHQFYPSMS 780
ESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHCQAHQFYPSMS
Sbjct: 721 ESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHCQAHQFYPSMS 780
Query: 781 QRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGCLWCADGQPAC 840
QRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGCLWCADGQPAC
Sbjct: 781 QRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGCLWCADGQPAC 840
Query: 841 RYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRP 900
RYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRP
Sbjct: 841 RYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRP 900
Query: 901 CNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPPGISSQHFTYQDPVLLSLSPRWG 960
CNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPPGISSQHFTYQDPVLLSLSPRWG
Sbjct: 901 CNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPPGISSQHFTYQDPVLLSLSPRWG 960
Query: 961 PQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVF 1020
PQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVF
Sbjct: 961 PQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVF 1020
Query: 1021 GHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAE 1080
GHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAE
Sbjct: 1021 GHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAE 1080
Query: 1081 VQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAVPDRA 1140
VQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAVPDRA
Sbjct: 1081 VQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAVPDRA 1140
Query: 1141 HPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGL 1200
HPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGL
Sbjct: 1141 HPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGL 1200
Query: 1201 NLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALG 1260
NLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALG
Sbjct: 1201 NLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALG 1260
Query: 1261 PVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESL 1320
PVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESL
Sbjct: 1261 PVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESL 1320
Query: 1321 ETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGP 1380
ETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGP
Sbjct: 1321 ETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGP 1380
Query: 1381 GEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLE 1440
GEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLE
Sbjct: 1381 GEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLE 1440
Query: 1441 YLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYML 1500
YLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYML
Sbjct: 1441 YLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYML 1500
Query: 1501 FRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQR 1560
FRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQR
Sbjct: 1501 FRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQR 1560
Query: 1561 VPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVT 1620
VPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVT
Sbjct: 1561 VPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVT 1620
Query: 1621 QNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCL 1680
QNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCL
Sbjct: 1621 QNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCL 1680
Query: 1681 WHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV 1740
WHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV
Sbjct: 1681 WHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV 1740
Query: 1741 NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSD 1800
NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSD
Sbjct: 1741 NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSD 1800
Query: 1801 NVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPAS 1860
NVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPAS
Sbjct: 1801 NVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPAS 1860
Query: 1861 YQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQ 1920
YQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQ
Sbjct: 1861 YQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQ 1920
Query: 1921 VAALVENKVTDL 1932
VAALVENKVTDL
Sbjct: 1921 VAALVENKVTDL 1932
>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
Length = 1909
Score = 3859 bits (10007), Expect = 0.0
Identities = 1894/1894 (100%), Positives = 1894/1894 (100%)
Query: 39 APVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLF 98
APVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLF
Sbjct: 16 APVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLF 75
Query: 99 QLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQV 158
QLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQV
Sbjct: 76 QLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQV 135
Query: 159 RQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGK 218
RQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGK
Sbjct: 136 RQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGK 195
Query: 219 LSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARA 278
LSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARA
Sbjct: 196 LSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARA 255
Query: 279 QAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLIQAAFLAPGTLLGVFAAGPRGTQAALC 338
QAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLIQAAFLAPGTLLGVFAAGPRGTQAALC
Sbjct: 256 QAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLIQAAFLAPGTLLGVFAAGPRGTQAALC 315
Query: 339 AFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHT 398
AFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHT
Sbjct: 316 AFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHT 375
Query: 399 PSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHS 458
PSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHS
Sbjct: 376 PSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHS 435
Query: 459 QQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCV 518
QQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCV
Sbjct: 436 QQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCV 495
Query: 519 LQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILD 578
LQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILD
Sbjct: 496 LQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILD 555
Query: 579 ADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATN 638
ADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATN
Sbjct: 556 ADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATN 615
Query: 639 FSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQV 698
FSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQV
Sbjct: 616 FSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQV 675
Query: 699 RGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATL 758
RGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATL
Sbjct: 676 RGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATL 735
Query: 759 EETAGDSGLIHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDC 818
EETAGDSGLIHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDC
Sbjct: 736 EETAGDSGLIHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDC 795
Query: 819 SHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTI 878
SHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTI
Sbjct: 796 SHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTI 855
Query: 879 LGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPP 938
LGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPP
Sbjct: 856 LGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPP 915
Query: 939 GISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCP 998
GISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCP
Sbjct: 916 GISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCP 975
Query: 999 EAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRV 1058
EAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRV
Sbjct: 976 EAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRV 1035
Query: 1059 RGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCS 1118
RGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCS
Sbjct: 1036 RGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCS 1095
Query: 1119 TVCSVNSSSLLLCRSPAVPDRAHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSR 1178
TVCSVNSSSLLLCRSPAVPDRAHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSR
Sbjct: 1096 TVCSVNSSSLLLCRSPAVPDRAHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSR 1155
Query: 1179 EGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQ 1238
EGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQ
Sbjct: 1156 EGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQ 1215
Query: 1239 PANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLM 1298
PANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLM
Sbjct: 1216 PANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLM 1275
Query: 1299 YRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRT 1358
YRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRT
Sbjct: 1276 YRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRT 1335
Query: 1359 YAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPS 1418
YAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPS
Sbjct: 1336 YAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPS 1395
Query: 1419 FSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLT 1478
FSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLT
Sbjct: 1396 FSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLT 1455
Query: 1479 NWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQP 1538
NWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQP
Sbjct: 1456 NWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQP 1515
Query: 1539 LTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALD 1598
LTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALD
Sbjct: 1516 LTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALD 1575
Query: 1599 LEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLA 1658
LEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLA
Sbjct: 1576 LEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLA 1635
Query: 1659 QRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTR 1718
QRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTR
Sbjct: 1636 QRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTR 1695
Query: 1719 LLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSL 1778
LLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSL
Sbjct: 1696 LLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSL 1755
Query: 1779 LLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYARE 1838
LLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYARE
Sbjct: 1756 LLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYARE 1815
Query: 1839 IPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQ 1898
IPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQ
Sbjct: 1816 IPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQ 1875
Query: 1899 IISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1932
IISALEEDPVGQKLQLACRLQQVAALVENKVTDL
Sbjct: 1876 IISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1909
>gi|194272180 plexin B1 [Homo sapiens]
Length = 2135
Score = 1264 bits (3272), Expect = 0.0
Identities = 690/1257 (54%), Positives = 842/1257 (66%), Gaps = 40/1257 (3%)
Query: 693 EVDIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELR 752
E++ G +CP VE + G L+PV E + L RNL F+ P C +EL G
Sbjct: 902 ELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEV 961
Query: 753 GLPATLE-ETAGDSGL-IHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYD 810
+ A +E E D+ + CQ HQ Q EL V +++ + R+D+ L+V+LYD
Sbjct: 962 VVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYD 1021
Query: 811 CAMGHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPG-AVELLCPAPSIDAVEPLTGP 869
C++GH DCS CQ A GC+WC +P C C AV CPAP I +VEPLTGP
Sbjct: 1022 CSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGP 1081
Query: 870 PEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPV 929
+GG +TI GSNLG+ DV V+VA PC + Y S+ +VC+T + G
Sbjct: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141
Query: 930 RVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGG--NTSAFVGG 987
V + + G+S F YQDP + S+ P GP+AGGT+LT+ G L TG + VG
Sbjct: 1142 AVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD 1201
Query: 988 QPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSA 1047
QPC +L E + C T P+ P V V FG +R L F+YT +P + +A P+
Sbjct: 1202 QPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTK 1261
Query: 1048 SFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQAC 1107
SF GGR I VRG LDVVQ P + V V + QP RR P+
Sbjct: 1262 SFLSGGREICVRGQNLDVVQTPRIRV------TVVSRMLQPSQGLGRRR----RVVPETA 1311
Query: 1108 IQLGGGLL--QCSTVCSVNSSSLLLCRSPAVPDRAHPQ--RVFFTLDNVQVDFASASGGQ 1163
LG Q C VNSS L+ CR+PA+P RV F LDN+ DFA+ +
Sbjct: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTP 1371
Query: 1164 GFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTL 1223
F Y+ +P L PL+ E P P+R KPG V VEGE L+L +SKEEV IG G C+VKTL
Sbjct: 1372 -FSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTL 1430
Query: 1224 TRTHLYCEPPAHAPQPANGS------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1277
TR HLYCEPP P P + + LP+F VQMGN++ +LG VQY+ E P AFPV A
Sbjct: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESP-GAFPVAA 1489
Query: 1278 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1337
Q G+G+G ++L V+++ LMYR KSKQALRDY+KV +QLE+LE+ V D+C+KEFTDLMT
Sbjct: 1490 QVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMT 1549
Query: 1338 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1397
EMTDL+SDL GSGIPFLDY+ YAER FFPGH PL P + TV QGL QLS
Sbjct: 1550 EMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVP--ESRRPTVEQGLGQLS 1607
Query: 1398 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1457
NLLNSKLFL IHTLE Q +FS RDR +VASLL++ALHGKLEY TDI+RTLL DL A Y
Sbjct: 1608 NLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQY 1667
Query: 1458 VHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVT 1517
V +NPKLMLRRTET+VEKLLTNW+SICLY F+R+ GEPLYMLFR I++QVDKGPVD+VT
Sbjct: 1668 VAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVT 1727
Query: 1518 GKAKRTLNDSRLLREDVEFQPLTLMVL--VGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1575
GKAK TLND+RLLREDVE++PLTL L VGPGAG A G VP +VLD DTI+Q K
Sbjct: 1728 GKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQG------VPVKVLDCDTISQAK 1781
Query: 1576 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1635
EK+LDQ+YKG P +QRP LD+EWRSG+AGHL LSDED+TS Q W+RLNTLQHYKV
Sbjct: 1782 EKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKV 1841
Query: 1636 PDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKV 1695
PDGATV LVP L + + + P GE P LED +EGG+ WHLVK ++EPE +
Sbjct: 1842 PDGATVALVPCLTKH--VLRENQDYVP-GERTPMLEDVDEGGIRPWHLVKPSDEPEPPRP 1898
Query: 1696 RCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLL 1755
R SLR E RAKAIPEIYLTRLLSMKGTLQKFVDD FQ ILS +RP+P+AVKY FDLL
Sbjct: 1899 RRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLL 1958
Query: 1756 DELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFID 1815
DE A++HGI D T+HIWKTNSL LRFW+N +KNPQ +FDV+ SDN+DA+L VIAQTF+D
Sbjct: 1959 DEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMD 2018
Query: 1816 SCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNY 1875
+CT ++HK+GRDSP+NKLLYAR+IPRYK+MVERYYADIRQ+ PAS QEMNS LAELS NY
Sbjct: 2019 ACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNY 2078
Query: 1876 TSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1932
+ AL ELY +I++YYDQII+ALEED QK+QL RLQQ+AA VENKVTDL
Sbjct: 2079 SGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
Score = 560 bits (1442), Expect = e-159
Identities = 326/717 (45%), Positives = 417/717 (58%), Gaps = 51/717 (7%)
Query: 46 PPFGLCLLLLL-----LSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQL 100
P G LL L L+ PLP T F+ T L HLA P GTLY+GA N LFQL
Sbjct: 2 PALGPALLQALWAGWVLTLQPLPPTA---FTPNGTYLQHLARDPTSGTLYLGATNFLFQL 58
Query: 101 SPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQVRQ 160
SP LQLEA TGPV+DS DC+P P ECPQAQ T+N NQLLLVS A LV CG V Q
Sbjct: 59 SPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
Query: 161 GVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVP-LPGRDLLLVARGLAGK- 218
GVCE RRLG + ++L + E PGD Q+VAAN P V+TVGLV L G LL V RG +
Sbjct: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
Query: 219 LSAGVPPLAIRQLAGSQP---FSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRG 275
+ G+PP+ R L P FS E +L VG S+Y++ +V AFA SAYF+F RR
Sbjct: 177 VGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRD 236
Query: 276 ARAQAE-YRSYVARVCLGDTNLYSYVEVPLACQG--QGLIQAAFLAPG-------TLLGV 325
+AQ+ +R+YV+RVCL D + YSYVE+PLAC+G GLIQAA +A L
Sbjct: 237 LQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAA 296
Query: 326 F--------------AAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEAT 371
F AAG G +ALCAFP+ E+ + R CYT GR G E A
Sbjct: 297 FSSAAPPTVGRPPSAAAGASGA-SALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
Query: 372 VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKL-GQPVSAVAALQADG 430
+EY V S C LP+D+ ++YPCG +HTPSP+A R PLE P+L+ G ++AVA DG
Sbjct: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
Query: 431 HMIAFLGDTQGQLYKVFLH-GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQV 489
H IAFLGD+QGQL++V+L GS G Y +Q + GSA+S DL D + HLYV+T +
Sbjct: 416 HTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI-QQGSAVSRDLTFDGTFEHLYVMTQSTL 474
Query: 490 DRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCL 549
++PVA+C Q DCASCL +DP CGWCVL GRC+R+ +C R QWLWS++ + CL
Sbjct: 475 LKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCL 534
Query: 550 HIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQD 609
+ ++ P + R+E +V LSVP LP L E + C FG++ S A + G V C +P
Sbjct: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
Query: 610 QVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWC 669
+ P+ P G D+V+V + L F V +A T+ SFYDC AV L +A C+ACV S W C+WC
Sbjct: 595 EAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWC 654
Query: 670 PQSSHCVYGEHCPEGERTIYSAQEV---DIQVRG-----PGACPQVEGLAGPHLVPV 718
C + C G + D RG P P+ P +PV
Sbjct: 655 VWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPV 711
>gi|40254442 plexin B1 [Homo sapiens]
Length = 2135
Score = 1264 bits (3272), Expect = 0.0
Identities = 690/1257 (54%), Positives = 842/1257 (66%), Gaps = 40/1257 (3%)
Query: 693 EVDIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELR 752
E++ G +CP VE + G L+PV E + L RNL F+ P C +EL G
Sbjct: 902 ELEEATLGASSCPCVESVQGSTLMPVHVEREIRLLGRNLHLFQDGPGDNECVMELEGLEV 961
Query: 753 GLPATLE-ETAGDSGL-IHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYD 810
+ A +E E D+ + CQ HQ Q EL V +++ + R+D+ L+V+LYD
Sbjct: 962 VVEARVECEPPPDTQCHVTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYD 1021
Query: 811 CAMGHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPG-AVELLCPAPSIDAVEPLTGP 869
C++GH DCS CQ A GC+WC +P C C AV CPAP I +VEPLTGP
Sbjct: 1022 CSVGHGDCSRCQTAMPQYGCVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGP 1081
Query: 870 PEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPV 929
+GG +TI GSNLG+ DV V+VA PC + Y S+ +VC+T + G
Sbjct: 1082 VDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGAT 1141
Query: 930 RVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGG--NTSAFVGG 987
V + + G+S F YQDP + S+ P GP+AGGT+LT+ G L TG + VG
Sbjct: 1142 AVEVPGRGRGVSEHDFAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD 1201
Query: 988 QPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSA 1047
QPC +L E + C T P+ P V V FG +R L F+YT +P + +A P+
Sbjct: 1202 QPCHLLPEQQSEQLRCETSPRPTPATLPVAVWFGATERRLQRGQFKYTLDPNITSAGPTK 1261
Query: 1048 SFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQAC 1107
SF GGR I VRG LDVVQ P + V V + QP RR P+
Sbjct: 1262 SFLSGGREICVRGQNLDVVQTPRIRV------TVVSRMLQPSQGLGRRR----RVVPETA 1311
Query: 1108 IQLGGGLL--QCSTVCSVNSSSLLLCRSPAVPDRAHPQ--RVFFTLDNVQVDFASASGGQ 1163
LG Q C VNSS L+ CR+PA+P RV F LDN+ DFA+ +
Sbjct: 1312 CSLGPSCSSQQFEEPCHVNSSQLITCRTPALPGLPEDPWVRVEFILDNLVFDFATLNPTP 1371
Query: 1164 GFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTL 1223
F Y+ +P L PL+ E P P+R KPG V VEGE L+L +SKEEV IG G C+VKTL
Sbjct: 1372 -FSYEADPTLQPLNPEDPTMPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCVVKTL 1430
Query: 1224 TRTHLYCEPPAHAPQPANGS------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1277
TR HLYCEPP P P + + LP+F VQMGN++ +LG VQY+ E P AFPV A
Sbjct: 1431 TRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESP-GAFPVAA 1489
Query: 1278 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1337
Q G+G+G ++L V+++ LMYR KSKQALRDY+KV +QLE+LE+ V D+C+KEFTDLMT
Sbjct: 1490 QVGLGVGTSLLALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMT 1549
Query: 1338 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1397
EMTDL+SDL GSGIPFLDY+ YAER FFPGH PL P + TV QGL QLS
Sbjct: 1550 EMTDLTSDLLGSGIPFLDYKVYAERIFFPGHRESPLHRDLGVP--ESRRPTVEQGLGQLS 1607
Query: 1398 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1457
NLLNSKLFL IHTLE Q +FS RDR +VASLL++ALHGKLEY TDI+RTLL DL A Y
Sbjct: 1608 NLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQY 1667
Query: 1458 VHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVT 1517
V +NPKLMLRRTET+VEKLLTNW+SICLY F+R+ GEPLYMLFR I++QVDKGPVD+VT
Sbjct: 1668 VAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVT 1727
Query: 1518 GKAKRTLNDSRLLREDVEFQPLTLMVL--VGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1575
GKAK TLND+RLLREDVE++PLTL L VGPGAG A G VP +VLD DTI+Q K
Sbjct: 1728 GKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQG------VPVKVLDCDTISQAK 1781
Query: 1576 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1635
EK+LDQ+YKG P +QRP LD+EWRSG+AGHL LSDED+TS Q W+RLNTLQHYKV
Sbjct: 1782 EKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKV 1841
Query: 1636 PDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKV 1695
PDGATV LVP L + + + P GE P LED +EGG+ WHLVK ++EPE +
Sbjct: 1842 PDGATVALVPCLTKH--VLRENQDYVP-GERTPMLEDVDEGGIRPWHLVKPSDEPEPPRP 1898
Query: 1696 RCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLL 1755
R SLR E RAKAIPEIYLTRLLSMKGTLQKFVDD FQ ILS +RP+P+AVKY FDLL
Sbjct: 1899 RRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLL 1958
Query: 1756 DELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFID 1815
DE A++HGI D T+HIWKTNSL LRFW+N +KNPQ +FDV+ SDN+DA+L VIAQTF+D
Sbjct: 1959 DEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMD 2018
Query: 1816 SCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNY 1875
+CT ++HK+GRDSP+NKLLYAR+IPRYK+MVERYYADIRQ+ PAS QEMNS LAELS NY
Sbjct: 2019 ACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAELSWNY 2078
Query: 1876 TSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1932
+ AL ELY +I++YYDQII+ALEED QK+QL RLQQ+AA VENKVTDL
Sbjct: 2079 SGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL 2135
Score = 560 bits (1442), Expect = e-159
Identities = 326/717 (45%), Positives = 417/717 (58%), Gaps = 51/717 (7%)
Query: 46 PPFGLCLLLLL-----LSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQL 100
P G LL L L+ PLP T F+ T L HLA P GTLY+GA N LFQL
Sbjct: 2 PALGPALLQALWAGWVLTLQPLPPTA---FTPNGTYLQHLARDPTSGTLYLGATNFLFQL 58
Query: 101 SPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLLLVSSRAQELVACGQVRQ 160
SP LQLEA TGPV+DS DC+P P ECPQAQ T+N NQLLLVS A LV CG V Q
Sbjct: 59 SPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQ 116
Query: 161 GVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVP-LPGRDLLLVARGLAGK- 218
GVCE RRLG + ++L + E PGD Q+VAAN P V+TVGLV L G LL V RG +
Sbjct: 117 GVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRG 176
Query: 219 LSAGVPPLAIRQLAGSQP---FSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRG 275
+ G+PP+ R L P FS E +L VG S+Y++ +V AFA SAYF+F RR
Sbjct: 177 VGGGIPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRD 236
Query: 276 ARAQAE-YRSYVARVCLGDTNLYSYVEVPLACQG--QGLIQAAFLAPG-------TLLGV 325
+AQ+ +R+YV+RVCL D + YSYVE+PLAC+G GLIQAA +A L
Sbjct: 237 LQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEGGRYGLIQAAAVATSREVAHGEVLFAA 296
Query: 326 F--------------AAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEAT 371
F AAG G +ALCAFP+ E+ + R CYT GR G E A
Sbjct: 297 FSSAAPPTVGRPPSAAAGASGA-SALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAY 355
Query: 372 VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKL-GQPVSAVAALQADG 430
+EY V S C LP+D+ ++YPCG +HTPSP+A R PLE P+L+ G ++AVA DG
Sbjct: 356 IEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDG 415
Query: 431 HMIAFLGDTQGQLYKVFLH-GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQV 489
H IAFLGD+QGQL++V+L GS G Y +Q + GSA+S DL D + HLYV+T +
Sbjct: 416 HTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSI-QQGSAVSRDLTFDGTFEHLYVMTQSTL 474
Query: 490 DRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCL 549
++PVA+C Q DCASCL +DP CGWCVL GRC+R+ +C R QWLWS++ + CL
Sbjct: 475 LKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCL 534
Query: 550 HIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQD 609
+ ++ P + R+E +V LSVP LP L E + C FG++ S A + G V C +P
Sbjct: 535 QVAAMSPANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPS 594
Query: 610 QVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWC 669
+ P+ P G D+V+V + L F V +A T+ SFYDC AV L +A C+ACV S W C+WC
Sbjct: 595 EAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWC 654
Query: 670 PQSSHCVYGEHCPEGERTIYSAQEV---DIQVRG-----PGACPQVEGLAGPHLVPV 718
C + C G + D RG P P+ P +PV
Sbjct: 655 VWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPV 711
>gi|149363636 plexin B2 [Homo sapiens]
Length = 1838
Score = 1210 bits (3131), Expect = 0.0
Identities = 764/1901 (40%), Positives = 1049/1901 (55%), Gaps = 141/1901 (7%)
Query: 77 LNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLT 136
LNHLA+ G +Y+GAVN L+QL +LQLE TGP +D+ C P + ++C +A++T
Sbjct: 34 LNHLAVDEASGVVYLGAVNALYQLDAKLQLEQQVATGPALDNKKCTPPIEASQCHEAEMT 93
Query: 137 DNANQLLLVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVAT 196
DN NQLLL+ + LV CG + +G+C R L +++ L+ + G+ FVA+N GVAT
Sbjct: 94 DNVNQLLLLDPPRKRLVECGSLFKGICALRALSNISLRLFYEDGSGEKSFVASNDEGVAT 153
Query: 197 VGLVVPL-PGRDLLLVARGLAGKLSAG--VPPLAIRQLAGSQPFSS-EGLGRLVVGDFSD 252
VGLV PG D +L G G V + + + F + G S
Sbjct: 154 VGLVSSTGPGGDRVLFVGKGNGPHDNGIIVSTRLLDRTDSREAFEAYTDHATYKAGYLST 213
Query: 253 YNNSYVGAFADARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQGLI 312
+V AF D +FVF ++ + A R+ +AR+C D N YSY+E+ L C+ +
Sbjct: 214 NTQQFVAAFEDGPYVFFVFNQQD-KHPARNRTLLARMCREDPNYYSYLEMDLQCRDPDIH 272
Query: 313 QAAF--------LAPGT---LLGVFAAGPR---GTQAALCAFPMVELGASMEQARRLCYT 358
AAF APG+ L VF+ R G A LC FP+ ++ A ME R CYT
Sbjct: 273 AAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPGAGLCLFPLDKVHAKMEANRNACYT 332
Query: 359 AGGRGPSGAEEAT----VEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLL 414
G EA + +C S +S+PCG EH P P+ R L +L
Sbjct: 333 -------GTREARDIFYKPFHGDIQCGGHAPGSSKSFPCGSEHLPYPLGSRDGLRGTAVL 385
Query: 415 KLGQ-PVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLL 473
+ G ++AV + H +AFLG + G++ KV+L + + + DL+
Sbjct: 386 QRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVYLTPDGTSSEYDSILVEINKRVKRDLV 445
Query: 474 LDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAG 533
L LY +T +V R+PV C +P C C +QDP CGWCV++GRCTRK +C RA
Sbjct: 446 LSGDLGSLYAMTQDKVFRLPVQECLSYPTCTQCRDSQDPYCGWCVVEGRCTRKAECPRAE 505
Query: 534 QLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDYDSL 593
+ + WLWS + C+ + S P + R+ QG+V L+V LP L ++ C FG+
Sbjct: 506 EASHWLWSRSKS--CVAVTSAQPQNMSRRAQGEVQLTVSPLPALSEEDELLCLFGESPPH 563
Query: 594 -AHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATNFS--FYDCSAVQAL 650
A VEG V C +P +P+ PPG DHV V + L+ + T++ FYDC +L
Sbjct: 564 PARVEGEAVICNSP--SSIPVTPPGQDHVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSL 621
Query: 651 EAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGL 710
E PC +CV + W C W + C E P E I A D +CPQ G
Sbjct: 622 EENLPCISCVSNRWTCQWDLRYHEC--REASPNPEDGIVRAHMED-------SCPQFLG- 671
Query: 711 AGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHC 770
P ++P+ E+ + + +NL +G +S H +L + P T++E+ +
Sbjct: 672 PSPLVIPMNHETDVNFQGKNLDTVKG--SSLHVGSDLLKFME--PVTMQESGTFAFRTPK 727
Query: 771 QAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGC 830
+H + LP+ +YV + + +D+ L+V LY+C+ G DCS C+AAN C
Sbjct: 728 LSHD-----ANETLPLHLYV-KSYGKNIDSK--LHVTLYNCSFGRSDCSLCRAANPDYRC 779
Query: 831 LWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADV 890
WC GQ C Y LC + CP P I ++P TGP GG+ +TILGSNLG D+
Sbjct: 780 AWCG-GQSRCVYEALCNTTSE---CPPPVITRIQPETGPLGGGIRITILGSNLGVQAGDI 835
Query: 891 QYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQ----PPGISSQHFT 946
Q +SVA R C+ +P Y S RIVCV A TG V V + + PP + FT
Sbjct: 836 Q-RISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVDVFGKLGRSPPNVQ---FT 891
Query: 947 YQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFV--GGQPCPILEPVCPEAIVCR 1004
+Q P LS+ P+ GPQAGGT LTI G HL TG V G PC + + + C
Sbjct: 892 FQQPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTK--FGAQLQCV 949
Query: 1005 TRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLD 1064
T PQA G+ + V +G + F Y NP L A EP SF GGR I V G G
Sbjct: 950 TGPQATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFASGGRSINVTGQGFS 1009
Query: 1065 VVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVN 1124
++QR + V E Q QP R A + P + T +
Sbjct: 1010 LIQRFAMVVIAEP----------LQSWQPPRE--AESLQPMTVV---------GTDYVFH 1048
Query: 1125 SSSLLLCRSPAVPDR--AHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPA 1182
+ + ++ SPAVP+ A+ V +D + + +G F Y P+P E
Sbjct: 1049 NDTKVVFLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGA--FEYVPDPTF-----ENFT 1101
Query: 1183 RPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANG 1242
+ + ++ G LN ++ +E +G C +KTLT T LYCEPP P P
Sbjct: 1102 GGVKKQVNKLIHARGTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRR 1161
Query: 1243 S------GLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLT 1296
LP+F+V+ G+ + LG V+Y+ +S P+ + + V++ AV +
Sbjct: 1162 QKRDTTHNLPEFIVKFGSREWVLGRVEYDTR--VSDVPLSLILPLVIVPMVVVIAVSVYC 1219
Query: 1297 LMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDY 1356
Y KS+QA R+Y+K+ QLE LE V D+C+KEFTDLM EM D ++D+ +GIP LDY
Sbjct: 1220 --YWRKSQQAEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEAGIPVLDY 1277
Query: 1357 RTYAERAFF----PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHT 1412
+TY +R FF G + K + P + V Q L Q SNLLNSK FL+ IHT
Sbjct: 1278 KTYTDRVFFLPSKDGDKDVMITGKLDIP--EPRRPVVEQALYQFSNLLNSKSFLINFIHT 1335
Query: 1413 LEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYV-HRNPKLMLRRTET 1471
LE Q FS R + + ASLL++ALHGKLEY TDIM TL +L YV +NPKLMLRR+ET
Sbjct: 1336 LENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKNPKLMLRRSET 1395
Query: 1472 MVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLR 1531
+VE++L+NW+SICLY +L++ AGEPLY LF+AI++QV+KGPVDAV KAK TLND+ LL
Sbjct: 1396 VVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAKYTLNDTGLLG 1455
Query: 1532 EDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQR 1591
+DVE+ PLT+ V+V + +P +VL+ DTI+QVKEK++DQVY+G P S
Sbjct: 1456 DDVEYAPLTVSVIVQ--------DEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCSCW 1507
Query: 1592 PSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGS 1651
P ++ LEWR G + LSD DLTS + WKR+NTL HY V DGAT+ L G
Sbjct: 1508 PRPDSVVLEWRPGSTAQI-LSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSKV---GV 1563
Query: 1652 TISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAI 1711
+ +Q+ GE LE+ +WHLV+ T+E + K + S++E+E R KAI
Sbjct: 1564 SQQPEDSQQDLPGERHALLEEENR----VWHLVRPTDEVDEGKSKRGSVKEKE--RTKAI 1617
Query: 1712 PEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPIPIAVKYLFDLLDELAEKHGIEDPGTLH 1771
EIYLTRLLS+KGTLQ+FVD+ FQ++L+ +P AVKY FD LDE AEKH I+D T+H
Sbjct: 1618 TEIYLTRLLSVKGTLQQFVDNFFQSVLAPGHAVPPAVKYFFDFLDEQAEKHNIQDEDTIH 1677
Query: 1772 IWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVN 1831
IWKTNSL LRFWVN LKNP IFDV V + VDA L+VIAQTF+D+CT +EHK+ RDSP N
Sbjct: 1678 IWKTNSLPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSN 1737
Query: 1832 KLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNH 1891
KLLYA+EI YK+MVE YY IRQ S Q+MN+ LAE+S +T + + L AL +LY +
Sbjct: 1738 KLLYAKEISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQY 1797
Query: 1892 IHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKVTDL 1932
+YYD+II+ALEEDP QK+QLA RLQQ+AA +ENKVTDL
Sbjct: 1798 TQKYYDEIINALEEDPAAQKMQLAFRLQQIAAALENKVTDL 1838
>gi|157694524 plexin D1 [Homo sapiens]
Length = 1925
Score = 967 bits (2500), Expect = 0.0
Identities = 704/2038 (34%), Positives = 1002/2038 (49%), Gaps = 242/2038 (11%)
Query: 14 LSPRLPGSFPQLRRVPPCSRPWLPKAPVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAP 73
++PR G P R S P P P L LLLLL + L RF +P
Sbjct: 1 MAPRAAGGAPLSARAAAASPPPFQTPPRC----PVPLLLLLLLGAARAGALEIQRRFPSP 56
Query: 74 NTTLNHLALAPGRGTLYVGAVNRLFQLS-PELQLEAVAVTGPVIDSPDC-VPFRDPAECP 131
T N+ AL GT+Y+ AVNRL+QLS L LEA A GPV DSP C P A C
Sbjct: 57 TPT-NNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCE 115
Query: 132 QAQ-LTDNANQLLLVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQ---AEDPGDGQFV 187
+ LTDN N++L + +V CG + QG C+ RR G+++ V + A P + V
Sbjct: 116 HPRRLTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTV 175
Query: 188 -------AANTPGVATVGLVVPLP---GRDLLLVARGLAGKLSA--------------GV 223
AAN P +TVGLV+P G LLV G S+
Sbjct: 176 FPSMLNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENT 235
Query: 224 PPLAIRQLAGSQPF----------SSEGLGRLVVGDFSDYNNSYVGAFAD-------ARS 266
P +AIR L S + + ++ G + +V AF A+S
Sbjct: 236 PEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQS 295
Query: 267 AYFVFRRRGARA---QAEYRSYVARVCL-----GDTNLY--SYVEVPLACQG-------Q 309
++ ARA +++ RS +AR+CL GD SY+++ L C G
Sbjct: 296 YAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAGRGDLY 355
Query: 310 GLIQAAFLAPGTLLGVF-----AAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGP 364
+ + F A L VF + R AALCAF ++ A++ AR C+
Sbjct: 356 SRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDV 415
Query: 365 SGAEEATVEYGVTSRC---VTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPVS 421
++ V+ G C + + L PE CG H P++ QPL+ P+ + ++
Sbjct: 416 VAVLDSVVQ-GTGPACERKLNIQLQ-PEQLDCGAAHLQHPLSILQPLKATPVFR-APGLT 472
Query: 422 AVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGS-H 480
+VA + + FLG G+L K+ L+ S V G + + D + S +
Sbjct: 473 SVAVASVNNYTAVFLGTVNGRLLKINLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGY 532
Query: 481 LYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLW 540
LY++T+HQ+ R+ VAAC C C+ A D CGWC L+ RCT + C + Q + W
Sbjct: 533 LYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTS 592
Query: 541 SYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVP-RLPILDADEYFHCAFGD-YDSLAHVEG 598
+ E S C + L RQE + L + LP L E C +G+ ++A V G
Sbjct: 593 ASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGME-MACDYGNNIRTVARVPG 651
Query: 599 PHVA-----CVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAA 653
P C P+DQ P PP DHVTV +++ + NF+ YDCS +
Sbjct: 652 PAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVRVNGRNIVKANFTIYDCSRTAQVYPH 711
Query: 654 APCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGLAGP 713
C +C+ + W C WC Q CV + S E P CP+ L P
Sbjct: 712 TACTSCLSAQWPCFWCSQQHSCVSNQ----------SRCEASPNPTSPQDCPRT--LLSP 759
Query: 714 HL-VPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHCQA 772
VP G ++ + + N F+G A+ C GL E + ++ C
Sbjct: 760 LAPVPTGGSQNILVPLANTAFFQG--AALECSF-------GLEEIFEAVWVNESVVRCDQ 810
Query: 773 HQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLG--C 830
+ + + P+ + + A+ LD+ + V++Y+CAMG PDCS C LG C
Sbjct: 811 VVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQC-LGREDLGHLC 869
Query: 831 LWCADGQPACRY-GPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFAD 889
+W +DG CR GPL P CPAP I A+EPL+GP +GG LTI G NLGR +D
Sbjct: 870 MW-SDG---CRLRGPLQPMAGT---CPAPEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSD 922
Query: 890 VQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPPGISSQHFTYQD 949
V + V + C P P Y S IVCVT PAP +G V V + G S F+Y
Sbjct: 923 VAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNASKE--GKSRDRFSYVL 980
Query: 950 PVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGG-QPCPILEPVCPEAIVCRTRPQ 1008
P++ SL P GP+AGGT++TI G L G V PC L +I C
Sbjct: 981 PLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRT-DTSIACTMPEG 1039
Query: 1009 AAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVVQR 1068
A P V V F F Y NP + A P S GGR I V G +VQ
Sbjct: 1040 ALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITVAGERFHMVQN 1099
Query: 1069 PLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVNSSSL 1128
++V ++P T+C V +S+L
Sbjct: 1100 VSMAV-----------HHIGREP---------------------------TLCKVLNSTL 1121
Query: 1129 LLCRSPAVPDRAHPQRVFFT-----LDNVQV-----DFASASGGQGFL--YQPNPRLAPL 1176
+ C SP A FF D V V D A G F Y PNP+ +
Sbjct: 1122 ITCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTA 1181
Query: 1177 SREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHA 1236
RE + + +P L + E +LG+ E RV IG+ C ++ ++ ++C +
Sbjct: 1182 KREKWIKHHPGEP-LTLVIHKEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCS--VNE 1238
Query: 1237 PQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLT 1296
A LP +Q+GN + +Q L + + + +L+ +V+ L
Sbjct: 1239 SLGAAVGQLP-ITIQVGNFNQTIATLQ------LGGSETAIIVSIVICSVLLLLSVVAL- 1290
Query: 1297 LMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGS-GIPFLD 1355
++ KS++A R +QK L+Q+E +E+ + ++ RK F +L T+MTDL+ +L S GIPFL+
Sbjct: 1291 FVFCTKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNRSQGIPFLE 1350
Query: 1356 YRTYAERAFFP------------------GHGGCPLQPKPEGPGE----DGHCATVRQGL 1393
Y+ + R FFP G Q GE + + +G+
Sbjct: 1351 YKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESCRPNMEEGI 1410
Query: 1394 TQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDL 1453
+ S+LLN+K FL+ +H LE+Q F+ RDRC +ASLL++ALHGKLEY T IM+ LL DL
Sbjct: 1411 SLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSIMKELLVDL 1470
Query: 1454 AAHYVHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPV 1513
+NPKLMLRRTE++VEK+LTNW+SIC+Y+ LRE GEP ++L AI+ Q++KG +
Sbjct: 1471 IDASAAKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSI 1530
Query: 1514 DAVTGKAKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQ 1573
DA+TGKA+ TLN+ LLRE++E +P L V G G M + R +DTDT+TQ
Sbjct: 1531 DAITGKARYTLNEEWLLRENIEAKPRNLNVSF-QGCG-------MDSLSVRAMDTDTLTQ 1582
Query: 1574 VKEKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHY 1633
VKEK+L+ K P+SQ P +DLEW + L D D TSV ++ K+LNTL HY
Sbjct: 1583 VKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNTLAHY 1642
Query: 1634 KVPDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGA 1693
K+P+GA++ + + +T+ + + L+ + +HLV T+E
Sbjct: 1643 KIPEGASLAMSLIDKKDNTLGR-----------VKDLDTEK-----YFHLVLPTDELAEP 1686
Query: 1694 KVRCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV--NRPIPIAVKYL 1751
K R+ R K +PEIYLTRLLS KGTLQKF+DD F+AILS+ ++P P+AVKY
Sbjct: 1687 KKS-----HRQSHRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKP-PLAVKYF 1740
Query: 1752 FDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQ 1811
FD L+E AEK GI DP TLHIWKTNSL LRFWVN LKNPQ +FD+ +D++DA L+VIAQ
Sbjct: 1741 FDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQ 1800
Query: 1812 TFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAEL 1871
FID+C+ S+ ++G+DSP NKLLYA+EIP Y+++V+RYY I+ +P S QEMN+ LAE
Sbjct: 1801 AFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEE 1860
Query: 1872 SGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKV 1929
S Y + + A+ E+Y + RY QI++ALE +P ++ QL + +QV AL+E+ +
Sbjct: 1861 SRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNI 1918
>gi|113722116 plexin A2 [Homo sapiens]
Length = 1894
Score = 966 bits (2496), Expect = 0.0
Identities = 668/1997 (33%), Positives = 997/1997 (49%), Gaps = 223/1997 (11%)
Query: 33 RPWLPKAPVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAPNT--TLNHLALAPGRGTLY 90
RPW P+A + L ++ +LL+PP + F + N T NHL + G G +Y
Sbjct: 5 RPW-PRALEVDSRSVVLLSVVWVLLAPPAAGMPQFSTFHSENRDWTFNHLTVHQGTGAVY 63
Query: 91 VGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQA-QLTDNANQLLLVSSRA 149
VGA+NR+++L+ L ++ TGP D+ C P C + LT+N N+LL++
Sbjct: 64 VGAINRVYKLTGNLTIQVAHKTGPEEDNKSCYPPLIVQPCSEVLTLTNNVNKLLIIDYSE 123
Query: 150 QELVACGQVRQGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRD-L 208
L+ACG + QGVC+ RL D+ +L + + + N G G++V G D
Sbjct: 124 NRLLACGSLYQGVCKLLRLDDLF-ILVEPSHKKEHYLSSVNKTGTM-YGVIVRSEGEDGK 181
Query: 209 LLVARGLAGKLSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDF---------------SDY 253
L + + GK P L+ R+L P SS L + DF S +
Sbjct: 182 LFIGTAVDGKQDY-FPTLSSRKLP-RDPESSAMLDYELHSDFVSSLIKIPSDTLALVSHF 239
Query: 254 NNSYVGAFADARSAYFVFRRR--------GARAQAEYRSYVARVCLGDTNLYSYVEVPLA 305
+ Y+ FA YF+ + + Y S + R+C D +SYV +P
Sbjct: 240 DIFYIYGFASGGFVYFLTVQPETPEGVAINSAGDLFYTSRIVRLCKDDPKFHSYVSLPFG 299
Query: 306 CQGQG----LIQAAFLA-PG--------------TLLGVFAAGPRG-----TQAALCAFP 341
C G L+QAA+LA PG L +F+ G + +ALCAFP
Sbjct: 300 CTRAGVEYRLLQAAYLAKPGDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFP 359
Query: 342 MVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSP 401
+ + +++ + CY G E G +C P+ +++ CG + P
Sbjct: 360 IRAINLQIKERLQSCYQGEGN-----LELNWLLGKDVQCTKAPVPIDDNF-CGLDIN-QP 412
Query: 402 IAGRQPLEVQPLLKLGQP-VSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQ--GQVYHS 458
+ G P+E L + +++VA+ +G+ + F+G G+L K+ G G Y
Sbjct: 413 LGGSTPVEGLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEM 472
Query: 459 QQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCV 518
V GS I D+ +LYV++ QV R+PV +C Q+ C CL + DP CGWC
Sbjct: 473 VSVLKDGSPILRDMAFSIDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCA 532
Query: 519 LQGRCTRKGQCGRAGQLNQWLWSYEED-SHCLHIQSLLPGHHPRQEQGQVTLSVPRLPIL 577
L C+R+ +C +A + N++ S + S +H S+ H R ++L V P L
Sbjct: 533 LHNMCSRRDKCQQAWEPNRFAASISQCVSLAVHPSSISVSEHSRL----LSLVVSDAPDL 588
Query: 578 DADEYFHCAFGDYDSL-AHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDV--TV 634
A CAFG+ + V G V C++P VP+ P D + L L ++
Sbjct: 589 SAG--IACAFGNLTEVEGQVSGSQVICISPGPKDVPVIPLDQDWFGLELQLRSKETGKIF 646
Query: 635 AATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEV 694
+T F FY+CSA Q C +CV S +RCHWC + C + + T S QE
Sbjct: 647 VSTEFKFYNCSAHQL------CLSCVNSAFRCHWCKYRNLCTH-------DPTTCSFQEG 693
Query: 695 DIQVRGPGACPQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGL 754
I + CPQ+ L+PVG + L+ RNL + + C L + G + +
Sbjct: 694 RINISED--CPQLVPTE-EILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRV 750
Query: 755 PATLEETAGDSGLIHCQAHQF-YPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAM 813
PA +S + CQ + Y M L V V +DN L V LY CA
Sbjct: 751 PAL----RFNSSSVQCQNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAA 806
Query: 814 GHPDCSHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEP 865
C C A+R C WC+ G+ C C + L C P I +
Sbjct: 807 QRESCGLCLKADRKFECGWCS-GERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILT 865
Query: 866 LTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGT 925
++GPPEGG +TI G NLG F+++ + V VA PC P P Y + +IVC A GT
Sbjct: 866 VSGPPEGGTRVTIHGVNLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVGT 925
Query: 926 T-GPVRVAIKSQPPGI---SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNT 981
T GPVR+ I P S Q +T+ +P +LSL+P GP++GGT +TI G +L G +
Sbjct: 926 TSGPVRLCIGECKPEFMTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSV 985
Query: 982 SAFVGGQPCPILEPVCPEAIVCRTRPQA---APGEAAVLVVFGHAQRTLLASPFRYTANP 1038
+ ++G Q C E IVC + P + P +V V H L F Y +P
Sbjct: 986 AVYLGNQTCEFYGRSMSE-IVCVSPPSSNGLGPVPVSVSVDRAHVDSNL---QFEYIDDP 1041
Query: 1039 QLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCG 1098
++ EP S G + + G LDV+Q P + V V
Sbjct: 1042 RVQRIEPEWSIASGHTPLTITGFNLDVIQEPRIRVKFNGKESVN---------------- 1085
Query: 1099 APAADPQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAVPDR--------AHPQRVFFTLD 1150
VC V +++ L C +P++ P F +
Sbjct: 1086 ---------------------VCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEFGFVFN 1124
Query: 1151 NVQVDFASASGGQGFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGL---NLGISKE 1207
NVQ F+Y PNP LS P KPG + ++G+ L G +K
Sbjct: 1125 NVQS--LLIYNDTKFIYYPNPTFELLS---PTGVLDQKPGSPIILKGKNLCPPASGGAKL 1179
Query: 1208 EVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAE 1267
V IG C V T++ T L CEPP N +G + +V +G + + G V ++
Sbjct: 1180 NYTVLIGETPCAV-TVSETQLLCEPP-------NLTGQHKVMVHVGGMVFSPGSVSVISD 1231
Query: 1268 PPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQ 1327
S + A + G ++L+ V+++ + Y+ KS++ +++ +Q+++LE+ V +
Sbjct: 1232 ---SLLTLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALE 1288
Query: 1328 CRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCA 1387
C++ F +L T++ +L+SDL+ SGIP+LDYRTYA R FPG P+ + E G
Sbjct: 1289 CKEAFAELQTDINELTSDLDRSGIPYLDYRTYAMRVLFPGIEDHPVLRELEVQGNGQQ-- 1346
Query: 1388 TVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMR 1447
V + L + L+N+K+FLLT I TLE Q SFS RDR +VASL+ L G+LEY TD+++
Sbjct: 1347 HVEKALKLFAQLINNKVFLLTFIRTLELQRSFSMRDRGNVASLIMTGLQGRLEYATDVLK 1406
Query: 1448 TLLGDLAAHYVHR--NPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQ 1505
LL DL + +PKL+LRRTE++ EK+LTNW + L+ FL+E AGEPL+ML+ AI+
Sbjct: 1407 QLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTNWFAFLLHKFLKECAGEPLFMLYCAIK 1466
Query: 1506 YQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARV 1565
Q++KGP+DA+TG+A+ +L++ +L+R+ +E++ L L V P + +P +V
Sbjct: 1467 QQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLILNC-VNPD------NENSPEIPVKV 1519
Query: 1566 LDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWK 1625
L+ DTITQVKEK+LD VYK P+SQRP +DLEWR G + L DED+T+ + WK
Sbjct: 1520 LNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARVVLQDEDITTKIEGDWK 1579
Query: 1626 RLNTLQHYKVPDGATVGLVPQ------LHRGSTISQSLAQRCP-----------LGENIP 1668
RLNTL HY+V D + V LVP+ + ++IS++ R L P
Sbjct: 1580 RLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISRYDSSFRYTGSPDSLRSRAP 1639
Query: 1669 TLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQ 1727
+ E GV +WHLVK + + ++E R +K + EIYLTRLL+ KGTLQ
Sbjct: 1640 MITPDLESGVKVWHLVKNHDHGD----------QKEGDRGSKMVSEIYLTRLLATKGTLQ 1689
Query: 1728 KFVDDTFQAILSV---NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWV 1784
KFVDD F+ + S +P+A+KY+FD LDE A++H I D H WK+N L LRFWV
Sbjct: 1690 KFVDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWKSNCLPLRFWV 1749
Query: 1785 NALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQ 1844
N +KNPQ +FD+ DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK
Sbjct: 1750 NVIKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKS 1809
Query: 1845 MVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALE 1904
VERYYADI + S Q+MN+ LAE S + + L AL E+Y+++ +Y +++I ALE
Sbjct: 1810 WVERYYADIAKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSKYSEELIGALE 1869
Query: 1905 EDPVGQKLQLACRLQQV 1921
+D ++ +LA +++Q+
Sbjct: 1870 QDEQARRQRLAYKVEQL 1886
>gi|49355818 plexin A1 [Homo sapiens]
Length = 1873
Score = 955 bits (2468), Expect = 0.0
Identities = 662/1958 (33%), Positives = 982/1958 (50%), Gaps = 219/1958 (11%)
Query: 70 FSAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAE 129
FSA + L HL + G +YVGAVNR+++LS L L VTGPV D+ C P
Sbjct: 21 FSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQS 80
Query: 130 CPQAQ-LTDNANQLLLVSSRAQELVACGQVRQGVCETRRLGDV---AEVLYQAEDPGDGQ 185
CP TDN N+LLL+ A L+ACG QG+C+ RL D+ E ++ E
Sbjct: 81 CPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSV 140
Query: 186 FVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQP--------F 237
A + GV G P G+ L V + GK S P L+ R+L ++ +
Sbjct: 141 QEAGSMAGVLIAG--PPGQGQAKLFVGTPIDGK-SEYFPTLSSRRLMANEEDADMFGFVY 197
Query: 238 SSEGLGRLV------VGDFSDYNNSYVGAFADARSAYFV-------FRRRGARAQAEYRS 284
E + + + F ++ YV +F + Y++ A + + S
Sbjct: 198 QDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTS 257
Query: 285 YVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA-PGTLLG--------------V 325
+ R+C+ D YSYVE P+ C+ G L+Q A+L+ PG L V
Sbjct: 258 KIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTV 317
Query: 326 FAAGPRGT-----QAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRC 380
FA G + ++ALC F + + +++ + CY G+ S E G C
Sbjct: 318 FAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGK-LSLPWLLNKELG----C 372
Query: 381 VTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPL-LKLGQPVSAVAALQADGHMIAFLGDT 439
+ PL + + CG + P+ G +E PL + ++AVAA G + F G
Sbjct: 373 INSPLQIDDDF-CGQDFN-QPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTR 430
Query: 440 QGQLYKVFLH----GSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVA 495
G++ K+ + G + + + V GS I DL+L + +LY +T QV R+PV
Sbjct: 431 SGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVTRVPVE 490
Query: 496 ACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLL 555
+C Q+ C CL ++DP CGWCVL C+R+ C RA + ++ + C +Q +
Sbjct: 491 SCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRFAADLLQ---C--VQLTV 545
Query: 556 PGHHPRQEQGQVTLSVPRLPILDADEYFHCAFGDY-DSLAHVEGPHVACVTPPQDQV-PL 613
+ QV L + + D +C+F D+ +S + +E + C +P +V P+
Sbjct: 546 QPRNVSVTMSQVPLVLQAWNVPDLSAGVNCSFEDFTESESVLEDGRIHCRSPSAREVAPI 605
Query: 614 NPPGTDHVTVPLALMFEDV--TVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQ 671
D V L L ++ A+ +F FY+CS Q+ C +CV + CHWC
Sbjct: 606 TRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCSVHQS------CLSCVNGSFPCHWCKY 659
Query: 672 SSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGLAGPHL-VPVGWESHLALRVRN 730
C + + ++ +V CPQ+ L + VPVG + L RN
Sbjct: 660 RHVCTHN---------VADCAFLEGRVNVSEDCPQI--LPSTQIYVPVGVVKPITLAARN 708
Query: 731 LQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHCQAHQF-YPSMSQRELPVPIY 789
L + + C +PG PA + +S + CQ + Y +LPV +
Sbjct: 709 LPQPQSGQRGYECLFHIPGS----PARVTALRFNSSSLQCQNSSYSYEGNDVSDLPVNLS 764
Query: 790 VTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLGCLWC-ADGQPACRYGPLCPP 848
V +DN + LY C C C A+ C WC A+ + + R+
Sbjct: 765 VVWNGNFVIDNPQNIQAHLYKCPALRESCGLCLKADPRFECGWCVAERRCSLRHHCAADT 824
Query: 849 GAVEL-------LCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPC 901
A + C P I + P TGP +GG LTI G NLG F DV+ V V C
Sbjct: 825 PASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLC 884
Query: 902 NPEPSLYRTSARIVCVTSPAPN--GTTGPVRVAIKSQPP---GISSQHFTYQDPVLLSLS 956
+P S Y ++ +IVC A + V V ++ P +S + FT+ P +S
Sbjct: 885 SPVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVTPTFYRVS 944
Query: 957 PRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAV 1016
P GP +GGT + I G HL G + + VGG+PC E I C T P +PG A +
Sbjct: 945 PSRGPLSGGTWIGIEGSHLNAGSDVAVSVGGRPCSFSWRNSRE-IRCLTPPGQSPGSAPI 1003
Query: 1017 LVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLE 1076
++ AQ T + YT +P ++ +P S GG L+ V GT L V+ P +
Sbjct: 1004 IININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRIRA--- 1060
Query: 1077 ADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAV 1136
+ GG ++ C V + + ++CR+P+V
Sbjct: 1061 --------------------------------KYGG--IERENGCLVYNDTTMVCRAPSV 1086
Query: 1137 --PDRAHPQ------RVFFTLDNVQVDFASASGGQGFLYQPNPRLAPLSREGPARPYRLK 1188
P R+ P+ + F +DNV+ S FLY P+P L PLS P LK
Sbjct: 1087 ANPVRSPPELGERPDELGFVMDNVRSLLVLNS--TSFLYYPDPVLEPLS---PTGLLELK 1141
Query: 1189 PGHVLDVEGEGL---NLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGSGL 1245
P L ++G L G S+ V IG C + T++ T L CE P N +G
Sbjct: 1142 PSSPLILKGRNLLPPAPGNSRLNYTVLIGSTPCTL-TVSETQLLCEAP-------NLTGQ 1193
Query: 1246 PQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQ 1305
+ V+ G + + G +Q ++ S + A G+G G +L+ ++ + + Y+ KS+
Sbjct: 1194 HKVTVRAGGFEFSPGTLQVYSD---SLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRD 1250
Query: 1306 ALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFF 1365
A R +++ +Q+++LE+ V +C++ F +L T++ +L++DL+G+GIPFLDYRTYA R F
Sbjct: 1251 ADRTLKRLQLQMDNLESRVALECKEAFAELQTDIHELTNDLDGAGIPFLDYRTYAMRVLF 1310
Query: 1366 PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRC 1425
PG P+ + E A V + LT LL K FLLT I TLE Q SFS RDR
Sbjct: 1311 PGIEDHPVLKEMEVQ------ANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRG 1364
Query: 1426 HVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVH--RNPKLMLRRTETMVEKLLTNWLSI 1483
+VASL+ AL G++EY T +++ LL DL + +PKL+LRRTE++ EK+LTNW +
Sbjct: 1365 NVASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTF 1424
Query: 1484 CLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMV 1543
LY FL+E AGEPL+ML+ AI+ Q++KGP+DA+TG+A+ +L++ +L+R+ ++++ LTL
Sbjct: 1425 LLYKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNC 1484
Query: 1544 LVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRS 1603
V P A VP + LD DT+TQ KEK+LD YKG P+SQRP +DLEWR
Sbjct: 1485 -VNPENENAP------EVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQ 1537
Query: 1604 GLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQ------LHRGSTISQSL 1657
G + L DED+T+ N WKRLNTL HY+V DG++V LVP+ + ST ++SL
Sbjct: 1538 GRMARIILQDEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTKSL 1597
Query: 1658 AQR----------CPLGENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPAR 1707
++ L P + E G LWHLVK + L +RE R
Sbjct: 1598 SRYESMLRTASSPDSLRSRTPMITPDLESGTKLWHLVKNHDH----------LDQREGDR 1647
Query: 1708 -AKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV---NRPIPIAVKYLFDLLDELAEKHG 1763
+K + EIYLTRLL+ KGTLQKFVDD F+ I S +P+A+KY+FD LDE A+KH
Sbjct: 1648 GSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHQ 1707
Query: 1764 IEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHK 1823
I D H WK+N L LRFWVN +KNPQ +FD+ + DA L+V+AQTF+DSC+TSEHK
Sbjct: 1708 IHDADVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHK 1767
Query: 1824 VGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLE 1883
+G+DSP NKLLYA++IP YK VERYYADI + S Q+M++ LAE S + S + +
Sbjct: 1768 LGKDSPSNKLLYAKDIPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLHLSQFNSMS 1827
Query: 1884 ALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQV 1921
AL E+Y++I +Y D+I++ALE+D ++ +L +L+QV
Sbjct: 1828 ALHEIYSYITKYKDEILAALEKDEQARRQRLRSKLEQV 1865
>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
Length = 1894
Score = 927 bits (2395), Expect = 0.0
Identities = 655/1991 (32%), Positives = 992/1991 (49%), Gaps = 246/1991 (12%)
Query: 56 LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 110
LL+ P PL+ R P NHL + G +Y+GAVNR+++LS +L++
Sbjct: 25 LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
Query: 111 VTGPVIDSPDCVPFRDPAECPQA-QLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 169
TGP D+P C P R C + T+N N++LL+ + L+ACG + QG+C+ RL
Sbjct: 85 ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
Query: 170 DVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRD-LLLVARGLAGKLSAGVPPLAI 228
D+ + L + + N G + G++V D L +A + GK P ++
Sbjct: 145 DLFK-LGEPYHKKEHYLSGVNESG-SVFGVIVSYSNLDDKLFIATAVDGKPEY-FPTISS 201
Query: 229 RQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYFVFR 272
R+L + ++G+ V D D++ YV F+ YF+
Sbjct: 202 RKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLTL 259
Query: 273 RR-------GARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLAP-G 320
+ + Y S + R+C DT SYVEVP+ C+ G L+QAA+L+ G
Sbjct: 260 QPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSKAG 319
Query: 321 TLLG--------------VFAAGPRGT-----QAALCAFPMVELGASMEQARRLCYTAGG 361
+LG VF+ G + ++ALC F + ++ +++ + CY
Sbjct: 320 AVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY---- 375
Query: 362 RGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPV- 420
RG + A ++ C + L +++ CG + PL V +++ G PV
Sbjct: 376 RGEGTLDLAWLKVKDIP-CSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIPVF 425
Query: 421 -------SAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQV--YHSQQVGPPGSAISPD 471
++V A H +AF+G G+L K+ + G +G Y + QV PG + D
Sbjct: 426 TEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQVVDPGPVLR-D 484
Query: 472 LLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGR 531
+ LY+++ Q+ R+PV +C Q+ C CL + DP CGWCVL CTRK +C R
Sbjct: 485 MAFSKDHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHNTCTRKERCER 544
Query: 532 AGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQ---EQGQVTLSVPRLPILDADEYFHCAFG 588
+ + ++ E C+ + HP Q V L + + + +C F
Sbjct: 545 SKEPRRFA---SEMKQCVRLTV-----HPNNISVSQYNVLLVLETYNVPELSAGVNCTFE 596
Query: 589 DYDSL-AHVEGPHVACVTPPQDQVP-LNPPGTDHVTVPLALMFED--VTVAATNFSFYDC 644
D + V G + C +P +VP + DH V L L ++ +T A+T+F FY+C
Sbjct: 597 DLSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMTFASTSFVFYNC 656
Query: 645 SAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGAC 704
S + C +CV S +RCHWC Y C +T S QE +++ P C
Sbjct: 657 SVHNS------CLSCVESPYRCHWCK------YRHVCTHDPKTC-SFQEGRVKL--PEDC 701
Query: 705 PQVEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGD 764
PQ+ + LVPV + L+ +NL + + C L + G + +PA +
Sbjct: 702 PQLLRV-DKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPAL----RFN 756
Query: 765 SGLIHCQAHQF-YPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQA 823
S + CQ + Y M LPV + V +DN V LY C C C
Sbjct: 757 SSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCLK 816
Query: 824 ANRSLGCLWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEPLTGPPEGGLA 875
A+ C WC G C CP + L C P I + P+TGP EGG
Sbjct: 817 ADPDFACGWC-QGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTK 875
Query: 876 LTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPA-PNGTTGPVRVAIK 934
+TI G NLG F D+ V VA C+P Y + +IVC A P+ G V + +
Sbjct: 876 VTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVA 935
Query: 935 SQPPGI---SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCP 991
P SSQ + + L L P GP +GGTQ+TI G +L G N G QPC
Sbjct: 936 VCRPEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGKQPC- 994
Query: 992 ILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQ--RTLLASPFRYTANPQLVAAEPSASF 1049
+ P IVC T E V V A+ + L+ F+Y +P +V EP S
Sbjct: 995 LFHRRSPSYIVCNTTSSDEVLEMKVSVQVDRAKIHQDLV---FQYVEDPTIVRIEPEWSI 1051
Query: 1050 RGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQ 1109
G I V GT LD++Q P +++A
Sbjct: 1052 VSGNTPIAVWGTHLDLIQNP----------QIRAKH------------------------ 1077
Query: 1110 LGGGLLQCSTVCSVNSSSLLLCRSPAV---PDRA-----HPQRVFFTLDNVQVDFASASG 1161
G + +C V +++ + C++PA+ PD P+ F LDNVQ
Sbjct: 1078 ---GGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQS--LLILN 1132
Query: 1162 GQGFLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVH----IGRGE 1217
F Y PNP GP+ LKPG + ++G+ L ++ V+++ +G
Sbjct: 1133 KTNFTYYPNPVFEAF---GPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKP 1189
Query: 1218 CLVKTLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA 1277
C V T++ L CE P N G + + ++G ++ + G V + PLS + A
Sbjct: 1190 CTV-TVSDVQLLCESP-------NLIGRHKVMARVGGMEYSPGMVYIAPDSPLS---LPA 1238
Query: 1278 QAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMT 1337
+ + +LI ++ + + Y+ KS+++ +++ +Q+++LE+ V +C++ F +L T
Sbjct: 1239 IVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQT 1298
Query: 1338 EMTDLSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLS 1397
++ +L+SDL+G+GIPFLDYRTY R FPG P+ E PG V +GL +
Sbjct: 1299 DIHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQE--RVEKGLKLFA 1356
Query: 1398 NLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHY 1457
L+N+K+FLL+ I TLE Q SFS RDR +VASL+ L KLEY TD+++ LL DL
Sbjct: 1357 QLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKN 1416
Query: 1458 VH--RNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDA 1515
+ +PKL+LRRTE++ EK+LTNW + LY FL+E AGEPL+ LF AI+ Q++KGP+DA
Sbjct: 1417 LESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDA 1476
Query: 1516 VTGKAKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVK 1575
+TG+A+ +L++ +L+R+ ++++ L L + + ++ VP ++L+ DTITQVK
Sbjct: 1477 ITGEARYSLSEDKLIRQQIDYKTLVLSCV-------SPDNANSPEVPVKILNCDTITQVK 1529
Query: 1576 EKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKV 1635
EK+LD ++K P S RP +DLEWR G + L DED+T+ +N WKRLNTL HY+V
Sbjct: 1530 EKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTLAHYQV 1589
Query: 1636 PDGATVGLVPQ------LHRGSTISQSLAQRCP-----------LGENIPTLEDGEEGGV 1678
PDG+ V LV + ST+S++ A + L P + E GV
Sbjct: 1590 PDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGV 1649
Query: 1679 CLWHLVKATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQKFVDDTFQAI 1737
+WHLVK E + ++E R +K + EIYLTRLL+ KGTLQKFVDD F+ I
Sbjct: 1650 KMWHLVKNHEHGD----------QKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETI 1699
Query: 1738 LSV---NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIF 1794
S +P+A+KY+FD LDE A+KHGI DP H WK+N L LRFWVN +KNPQ +F
Sbjct: 1700 FSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVF 1759
Query: 1795 DVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIR 1854
D+ + DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK VERYY+DI
Sbjct: 1760 DIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIG 1819
Query: 1855 QSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQL 1914
+ S Q+MN+ LAE S + + + + AL E+++++ +Y ++I+ L+ D K +L
Sbjct: 1820 KMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKL 1879
Query: 1915 ACRLQQVAALV 1925
A +L+QV L+
Sbjct: 1880 AYKLEQVITLM 1890
>gi|59710104 plexin A3 [Homo sapiens]
Length = 1871
Score = 913 bits (2359), Expect = 0.0
Identities = 645/1988 (32%), Positives = 976/1988 (49%), Gaps = 232/1988 (11%)
Query: 50 LCLLLLLLSPPPLPLTGA------HRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPE 103
+CLLLLL L + GA F +TTL HLA+ G ++VGAVNR+F+L+P
Sbjct: 4 VCLLLLLF----LAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPN 59
Query: 104 LQLEAVAVTGPVIDSPDCVPFRDPAECPQAQL-TDNANQLLLVSSRAQELVACGQVRQGV 162
L VTGPV D+ C P C DN N+LLL+ A+ LVACG + QG+
Sbjct: 60 LTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGI 119
Query: 163 CETRRLGDVAEVLYQAEDPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAG 222
C+ RL D+ + L + + A P +V G L V + GK S
Sbjct: 120 CQFLRLDDLFK-LGEPHHRKEHYLSGAQEPDSMAGVIVEQGQGPSKLFVGTAVDGK-SEY 177
Query: 223 VPPLAIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARS 266
P L+ R+L + S + LV D + ++ Y+ F A
Sbjct: 178 FPTLSSRKLISDE--DSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASF 235
Query: 267 AYFVFRRRGAR-------AQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAA 315
YF+ + + + + S + R+C GD+ YSYVE P+ C +G L+Q+A
Sbjct: 236 VYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSA 295
Query: 316 FLA-PGTLLG--------------VFAAGPRGT-----QAALCAFPMVELGASMEQARRL 355
LA PG LL +F+ G + Q LC F + + A + + +
Sbjct: 296 HLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQS 355
Query: 356 CYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLK 415
CY RG G C+ P+ ++ CG P+ G +E PLL
Sbjct: 356 CY----RG-EGTLALPWLLNKELPCINTPMQINGNF-CGLVLN-QPLGGLHVIEGLPLLA 408
Query: 416 LGQP-VSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLL 474
+++VAA H + F+G G L KV + G Q + GS I DLL
Sbjct: 409 DSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLF 468
Query: 475 DSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQ 534
H+Y+L+ QV ++PV C Q+ CA+CL + DP CGWCVL+ RC R+G C A
Sbjct: 469 SPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASA 528
Query: 535 LNQWLWSYEEDSHCLHIQSLLPGHHPRQEQG-QVTLSVPRLPILDADEYFHCAF---GDY 590
+ + EE S C+ ++ + P + G Q+T+++ +P L A CAF +
Sbjct: 529 PHGFA---EELSKCVQVR-VRPNNVSVTSPGVQLTVTLHNVPDLSAG--VSCAFEAAAEN 582
Query: 591 DSLAHVEGPHVACVTPPQDQVPLNPPGTDHV-TVPLALMFEDVTV--AATNFSFYDCSAV 647
+++ G + C +P ++ G TV L L+ ++ V A +F FY+CS +
Sbjct: 583 EAVLLPSG-ELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVL 641
Query: 648 QALEAAAPCRACVGSIWRCHWCPQSSHCVYGEH-CPEGERTIYSAQEVDIQVRGPGACPQ 706
Q+ C +CVGS + CHWC C H C E ++S P CP+
Sbjct: 642 QS------CMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHS----------PEGCPE 685
Query: 707 VEGLAGPHLVPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSG 766
+ +G L+PVG L LR +NL + ++ C + + G + +PA +S
Sbjct: 686 ILP-SGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAV----RFNSS 740
Query: 767 LIHCQ-AHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAAN 825
+ CQ A Y + + V +D + +LY C P C C A+
Sbjct: 741 SVQCQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKAD 800
Query: 826 RSLGCLWCADGQPACRYGPLCPPGAVELL--------CPAPSIDAVEPLTGPPEGGLALT 877
C WC + C+ CP + C P I + PL GP EGG +T
Sbjct: 801 PRFNCGWCIS-EHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVT 859
Query: 878 ILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVT--SPAPNGTTGPVRVAIKS 935
I+G NLG +V + VA CN P+ Y ++ RIVC S P+ GPV + +
Sbjct: 860 IVGDNLGLLSREV--GLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGD 917
Query: 936 QPPGI---SSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPI 992
S Q +++ P +SP GP +GGT+LTI G L G + V C
Sbjct: 918 CSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQF 977
Query: 993 LEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGG 1052
+ + P +A + + A + + YT +P + EP+ S G
Sbjct: 978 VRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIING 1037
Query: 1053 GRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGG 1112
I V GT L VQ P + RA+ +
Sbjct: 1038 STAITVSGTHLLTVQEPRV-------------RAKYRG---------------------- 1062
Query: 1113 GLLQCSTVCSVNSSSLLLCRSPAV--------PDRAHPQRVFFTLDNVQVDFASASGGQG 1164
++ + C V + + +LC++P + HP F LD+VQ A +
Sbjct: 1063 --IETTNTCQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQT--ARSLNRSS 1118
Query: 1165 FLYQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGL---NLGISKEEVRVHIGRGECLVK 1221
F Y P+P PL GP+ +KPG + ++G+ L G S+ V IG C +
Sbjct: 1119 FTYYPDPSFEPL---GPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSL- 1174
Query: 1222 TLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGV 1281
T++ T L C+ P+ +G +V +G ++ LG + AE L+ + A G+
Sbjct: 1175 TVSDTQLLCDSPSQ-------TGRQPVMVLVGGLEFWLGTLHISAERALT---LPAMMGL 1224
Query: 1282 GMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTD 1341
G +L+ A+ + + Y+ K++ A R +++ +Q+++LE+ V +C++ F +L T++ +
Sbjct: 1225 AAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINE 1284
Query: 1342 LSSDLEGSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLN 1401
L++ ++ IPFLDYRTYA R FPG P+ + + P V + L LL+
Sbjct: 1285 LTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTP------PNVEKALRLFGQLLH 1338
Query: 1402 SKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVH-- 1459
S+ F+LT IHTLE Q SFS RDR VASL +AL +L+Y T +++ LL DL +
Sbjct: 1339 SRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESK 1398
Query: 1460 RNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGK 1519
+PKL+LRRTE++ EK+LTNW + L+ FL+E AGEPL++L+ AI+ Q++KGP+DA+TG+
Sbjct: 1399 NHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGE 1458
Query: 1520 AKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVL 1579
A+ +L++ +L+R+ ++++ LTL + G A +VP +VL+ D+ITQ K+K+L
Sbjct: 1459 ARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSA-------QVPVKVLNCDSITQAKDKLL 1511
Query: 1580 DQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGA 1639
D VYKG P+SQRP +DLEWR G + L DED+T+ + WKRLN+L HY+V DG+
Sbjct: 1512 DTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGS 1571
Query: 1640 TVGLVPQ----------------LHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHL 1683
V LVP+ L R ++ ++ + L P + +E G LWHL
Sbjct: 1572 LVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHL 1631
Query: 1684 VKATEEPEGAKVRCSSLREREPAR-AKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV-- 1740
VK + + RE R +K + EIYLTRLL+ KGTLQKFVDD F+ + S
Sbjct: 1632 VKNHDHAD----------HREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAH 1681
Query: 1741 -NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVS 1799
+P+A+KY+FD LDE A++ I DP H WK+N L LRFWVN +KNPQ +FD+ +
Sbjct: 1682 RGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKN 1741
Query: 1800 DNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPA 1859
DA L+V+AQTF+DSC+TSEH++G+DSP NKLLYA++IP YK VERYY DI + +
Sbjct: 1742 SITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASI 1801
Query: 1860 SYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQ 1919
S Q+M++ L E S + S L AL ELY ++ +Y +I++AL+ D +K +L +L+
Sbjct: 1802 SDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLE 1861
Query: 1920 QVAALVEN 1927
Q+ +LV +
Sbjct: 1862 QIISLVSS 1869
>gi|5032223 plexin C1 [Homo sapiens]
Length = 1568
Score = 384 bits (986), Expect = e-106
Identities = 249/724 (34%), Positives = 389/724 (53%), Gaps = 56/724 (7%)
Query: 1195 VEGEGLNLGISKEEVRVHIGRGE-----CLVKTLTR----THLYCEPPAHAPQPANGSGL 1245
++ E N ISK+++ + + GE C + +TR T + C+ +
Sbjct: 863 IQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSS 922
Query: 1246 PQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQ 1305
+ V++GN++L V+ E+ P F + +L+ + + RHKSK+
Sbjct: 923 KKVRVKLGNLELY---VEQESVPSTWYFLIVLPV-------LLVIVIFAAVGVTRHKSKE 972
Query: 1306 ALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGSGIPFLDYRTYAERAFF 1365
R + QLE LE+ + + R F +L + D+ +PFLDY+ +A R FF
Sbjct: 973 LSRKQSQ---QLELLESELRKEIRDGFAELQMDKLDVVDSF--GTVPFLDYKHFALRTFF 1027
Query: 1366 PGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRC 1425
P GG + D + + LT L L+ +K FL+T+IHTLE+Q +FS +DRC
Sbjct: 1028 PESGGFTHIFTEDMHNRDAN--DKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRC 1085
Query: 1426 HVASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLTNWLSICL 1485
AS L++AL KL YLT I+ L DL + PKLMLRRTE++VEKLLTNW+S+CL
Sbjct: 1086 LFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCL 1145
Query: 1486 YAFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVLV 1545
FLRE GEP Y+L + +++KGPVD +T KA TLN+ LL + EF + L V+
Sbjct: 1146 SGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVF 1205
Query: 1546 GPGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYK--GTPFSQRPSVHALDLEWRS 1603
+ + + + VLD DTI Q KEK+ G+P+ + ++ + LE +
Sbjct: 1206 EKIPENES-ADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQ--LNEIGLELQM 1262
Query: 1604 GLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLAQRCPL 1663
G L + + + ++ +LNT+ HY++ +G+T+ + ++ ++ + C L
Sbjct: 1263 GTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKKIANFTSDVEYSDDHCHL 1322
Query: 1664 GENIPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTRLLSMK 1723
L D E A ++ +G R R + K + E+YLT+LLS K
Sbjct: 1323 -----ILPDSE-----------AFQDVQGK-------RHRGKHKFK-VKEMYLTKLLSTK 1358
Query: 1724 GTLQKFVDDTFQAILSV-NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRF 1782
+ ++ F++I S+ N P A+KY FD LD AE I DP +HIWKTNSL LRF
Sbjct: 1359 VAIHSVLEKLFRSIWSLPNSRAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRF 1418
Query: 1783 WVNALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRY 1842
WVN LKNPQ +FD++ + ++D L+VIAQ F+D+ + +E ++G+++P NKLLYA++IP Y
Sbjct: 1419 WVNILKNPQFVFDIKKTPHIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTY 1478
Query: 1843 KQMVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISA 1902
K+ V+ YY IR P S EM L + S + + + AL E+Y +I +Y+D+I++
Sbjct: 1479 KEEVKSYYKAIRDLPPLSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNK 1538
Query: 1903 LEED 1906
LE +
Sbjct: 1539 LERE 1542
Score = 83.6 bits (205), Expect = 2e-15
Identities = 75/293 (25%), Positives = 117/293 (39%), Gaps = 51/293 (17%)
Query: 404 GRQPLEVQPLLK---LGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQ-----V 455
G QP VQP+ + +++V + FLG GQL KV L + +
Sbjct: 357 GDQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLLKVILGENLTSNCPEVI 416
Query: 456 YHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCG 515
Y ++ P + PD + ++Y+ +V RI VA C + C+ CL A DP CG
Sbjct: 417 YEIKEETPVFYKLVPDPV---KNIYIYLTAGKEVRRIRVANCNKHKSCSECLTATDPHCG 473
Query: 516 WCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVPRLP 575
WC RCT +G C + L WL C IQ + +E+ VT+ P
Sbjct: 474 WCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQII----RSSKEKTTVTMVGSFSP 529
Query: 576 ILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVA 635
+ C + DS + C Q P T ++P ++DV+V
Sbjct: 530 -----RHSKCMVKNVDSSREL------CQNKSQ------PNRTCTCSIPTRATYKDVSVV 572
Query: 636 -----------ATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVY 677
+ F+F +CS+++ C ACV + C WC + C++
Sbjct: 573 NVMFSFGSWNLSDRFNFTNCSSLK------ECPACVET--GCAWCKSARRCIH 617
>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
Length = 522
Score = 120 bits (301), Expect = 1e-26
Identities = 128/481 (26%), Positives = 211/481 (43%), Gaps = 88/481 (18%)
Query: 56 LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 110
LL+ P PL+ R P NHL + G +Y+GAVNR+++LS +L++
Sbjct: 25 LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
Query: 111 VTGPVIDSPDCVPFRDPAECPQ-AQLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 169
TGP D+P C P R C + T+N N++LL+ + L+ACG + QG+C+ RL
Sbjct: 85 ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
Query: 170 DVAEVLYQAEDP--GDGQFVAANTPGVATVGLVVPLPG-RDLLLVARGLAGKLSAGVPPL 226
D L++ +P +++ + G++V D L +A + GK P +
Sbjct: 145 D----LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGK-PEYFPTI 199
Query: 227 AIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYF- 269
+ R+L + ++G+ V D D++ YV F+ YF
Sbjct: 200 SSRKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFL 257
Query: 270 ------VFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA- 318
V + Y S + R+C DT SYVEVP+ C+ G L+QAA+L+
Sbjct: 258 TLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSK 317
Query: 319 PGTLLG--------------VFAAGPRG-----TQAALCAFPMVELGASMEQARRLCYTA 359
G +LG VF+ G + ++ALC F + ++ +++ + CY
Sbjct: 318 AGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY-- 375
Query: 360 GGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQP 419
RG + A ++ C + L +++ CG + PL V +++ G P
Sbjct: 376 --RGEGTLDLAWLKV-KDIPCSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIP 423
Query: 420 V--------SAVAALQADGHMIAFLGDTQGQLYKVFLHGSQG---QVYHSQQVGPPGSAI 468
V ++V A H +AF+G G+L K F G QG Q + + PPG+ I
Sbjct: 424 VFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKSFGTGPQGGITQEWIGVEGDPPGANI 483
Query: 469 S 469
+
Sbjct: 484 A 484
>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
Length = 492
Score = 112 bits (280), Expect = 4e-24
Identities = 119/455 (26%), Positives = 199/455 (43%), Gaps = 85/455 (18%)
Query: 56 LLSPPPLPLTGAHRF-----SAPNTTLNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVA 110
LL+ P PL+ R P NHL + G +Y+GAVNR+++LS +L++
Sbjct: 25 LLTRQPAPLSQKQRSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTH 84
Query: 111 VTGPVIDSPDCVPFRDPAECPQ-AQLTDNANQLLLVSSRAQELVACGQVRQGVCETRRLG 169
TGP D+P C P R C + T+N N++LL+ + L+ACG + QG+C+ RL
Sbjct: 85 ETGPDEDNPKCYPPRIVQTCNEPLTTTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLE 144
Query: 170 DVAEVLYQAEDP--GDGQFVAANTPGVATVGLVVPLPG-RDLLLVARGLAGKLSAGVPPL 226
D L++ +P +++ + G++V D L +A + GK P +
Sbjct: 145 D----LFKLGEPYHKKEHYLSGVNESGSVFGVIVSYSNLDDKLFIATAVDGK-PEYFPTI 199
Query: 227 AIRQLAGSQPFSSEGLGRLVVGD----------------FSDYNNSYVGAFADARSAYF- 269
+ R+L + ++G+ V D D++ YV F+ YF
Sbjct: 200 SSRKLTKNS--EADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFL 257
Query: 270 ------VFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPLACQGQG----LIQAAFLA- 318
V + Y S + R+C DT SYVEVP+ C+ G L+QAA+L+
Sbjct: 258 TLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSGVEYRLLQAAYLSK 317
Query: 319 PGTLLG--------------VFAAGPRG-----TQAALCAFPMVELGASMEQARRLCYTA 359
G +LG VF+ G + ++ALC F + ++ +++ + CY
Sbjct: 318 AGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKERLQSCY-- 375
Query: 360 GGRGPSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQP 419
RG + A ++ C + L +++ CG + PL V +++ G P
Sbjct: 376 --RGEGTLDLAWLKV-KDIPCSSALLTIDDNF-CG-------LDMNAPLGVSDMVR-GIP 423
Query: 420 V--------SAVAALQADGHMIAFLGDTQGQLYKV 446
V ++V A H +AF+G G+L K+
Sbjct: 424 VFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKM 458
>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
Length = 1390
Score = 100 bits (249), Expect = 1e-20
Identities = 144/595 (24%), Positives = 223/595 (37%), Gaps = 93/595 (15%)
Query: 818 CSHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALT 877
CS C +A + C WC D C C G P+I V P + P EGG LT
Sbjct: 526 CSQCLSAPPFVQCGWCHD---KCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLT 582
Query: 878 ILGSNLG----RAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAI 933
I G + G F + V + + C S T + C PA N + + I
Sbjct: 583 ICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLS-ESTMNTLKCTVGPAMNKHFN-MSIII 640
Query: 934 KSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPIL 993
+ F+Y DPV+ S+SP++GP AGGT LT+ G +L +G + +GG+ C L
Sbjct: 641 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTC-TL 699
Query: 994 EPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGG 1053
+ V + C T Q E AV + A R S F Y +P + P+ SF GG
Sbjct: 700 KSVSNSILECYTPAQTISTEFAVKLKIDLANRE--TSIFSYREDPIVYEIHPTKSFISGG 757
Query: 1054 RLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGG 1113
I G L+ V P + + + A AC
Sbjct: 758 STITGVGKNLNSVSVPRMVINVHE---------------------AGRNFTVACQHRSNS 796
Query: 1114 LLQCSTVCSVNSSSLLLCRSPAVPDRAHPQRVFFTLDNVQVDFASASGGQGFLYQPNPRL 1173
+ C T S+ +L L + FF LD + + +Y NP
Sbjct: 797 EIICCTTPSLQQLNLQL---------PLKTKAFFMLDGILSKYFD------LIYVHNPVF 841
Query: 1174 APLSREGPARPYRLKPG--HVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCE 1231
P +P + G +VL+++G ++ K EV + +G C HL+ E
Sbjct: 842 KPFE-----KPVMISMGNENVLEIKGNDIDPEAVKGEV-LKVGNKSC-----ENIHLHSE 890
Query: 1232 PPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEA-QAGVGMGAAVL-- 1288
A +P ++++ N +L + Q + L V+ Q G+ A V+
Sbjct: 891 --------AVLCTVPNDLLKL-NSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSI 941
Query: 1289 -IAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLE 1347
A +LLL K ++ ++D LV+ ++ + D + +S E
Sbjct: 942 STALLLLLGFFLWLKKRKQIKDLGSELVRYDA-------RVHTPHLDRLVSARSVSPTTE 994
Query: 1348 GSGIPFLDYRTYAERAFFPGHGGCPLQPKPEGPGEDGHCATVRQGLTQLSNLLNS 1402
+DYR FP ++G C V+ LT +S +L S
Sbjct: 995 MVSNESVDYRATFPEDQFP------------NSSQNGSCRQVQYPLTDMSPILTS 1037
Score = 79.0 bits (193), Expect = 4e-14
Identities = 116/525 (22%), Positives = 205/525 (39%), Gaps = 119/525 (22%)
Query: 89 LYVGAVNRLFQLSPE-LQLEAVAVTGPVIDSPDCVPFRD---PAECPQAQLTDNANQLLL 144
+++GA N ++ L+ E LQ A TGPV++ PDC P +D A DN N L+
Sbjct: 62 IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMALV 121
Query: 145 VSS-RAQELVACGQVRQGVCET-----RRLGDVAEVLY-----QAEDPGDGQFVAANTPG 193
V + +L++CG V +G C+ D+ ++ Q E+P + G
Sbjct: 122 VDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSALG 181
Query: 194 VATVGLVVPLPGRDLLL---VARGLAGKLSAGVP--PLAIRQLAGSQP---FSSEGLGRL 245
+ V +D + V + P +++R+L ++ F ++
Sbjct: 182 AKVLSSV-----KDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYID 236
Query: 246 VVGDFSD-YNNSYVGAFADARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPL 304
V+ +F D Y YV AF YF+ +R + + + R C ++ L+SY+E+PL
Sbjct: 237 VLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPL 296
Query: 305 AC-------------QGQGLIQAAFLA-PGT--------------LLGVFAAGPRGT--- 333
C + ++QAA+++ PG L GVFA +
Sbjct: 297 ECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEP 356
Query: 334 --QAALCAFPMVELG------ASMEQARRLCYTAGG-----------RGPSGAEEATVEY 374
++A+CAFP+ + + R L + G R SG E EY
Sbjct: 357 MDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEY 416
Query: 375 GVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQ----PVSAVAALQADG 430
+D L +GQ +++++
Sbjct: 417 RTEFTTALQRVD---------------------------LFMGQFSEVLLTSISTFIKGD 449
Query: 431 HMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLD---SSGSHLYVLTAH 487
IA LG ++G+ +V + S H + +SP+++++ + + V+T
Sbjct: 450 LTIANLGTSEGRFMQVVVSRSGPSTPHVNFL-LDSHPVSPEVIVEHTLNQNGYTLVITGK 508
Query: 488 QVDRIPV--AACPQFPDCASCLQAQDPL-CGWCVLQGRCTRKGQC 529
++ +IP+ C F C+ CL A + CGWC +C R +C
Sbjct: 509 KITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWC--HDKCVRSEEC 551
>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
sapiens]
Length = 1400
Score = 94.7 bits (234), Expect = 8e-19
Identities = 72/255 (28%), Positives = 109/255 (42%), Gaps = 29/255 (11%)
Query: 818 CSHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALT 877
C C A +GC WC + C CP + CP P + P +GP G LT
Sbjct: 533 CGRCLRAWHFMGCGWCGN---MCGQQKECPGSWQQDHCP-PKLTEFHPHSGPLRGSTRLT 588
Query: 878 ILGSNL----GRAFADVQYAVSVASRPCNPEP---SLYRTSAR------IVCVTSPAPNG 924
+ GSN + + V+V PC P P S R R C P
Sbjct: 589 LCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFECELEPLGTQ 648
Query: 925 TTGPVRVA--IKSQPPGISSQ--------HFTYQDPVLLSLSPRWGPQAGGTQLTIRGQH 974
GP V+ + + PPG + F++ +PVL+++ P +GP+AGGT LT+ GQ
Sbjct: 649 AVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAGGTCLTLEGQS 708
Query: 975 LQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRY 1034
L G + + V G C +L V ++C T P A + + G AQ + F+Y
Sbjct: 709 LSVGTSRAVLVNGTEC-LLARVSEGQLLCATPPGATVASVPLSLQVGGAQ-VPGSWTFQY 766
Query: 1035 TANPQLVAAEPSASF 1049
+P +++ P+ +
Sbjct: 767 REDPVVLSISPNCGY 781
Score = 61.2 bits (147), Expect = 9e-09
Identities = 144/656 (21%), Positives = 223/656 (33%), Gaps = 105/656 (16%)
Query: 46 PPFGLCLLLLLLSP-----------PPLPLTGAHRFSA----PNTTLNHLALAP------ 84
PP LLLLL P P P + F P+ + L A
Sbjct: 5 PPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVTYEGD 64
Query: 85 -GRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQAQLTDNANQLL 143
++V NRL L P+L+ TGP D P C P D ++L
Sbjct: 65 RNESAVFVAIRNRLHVLGPDLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPGDTDTKVL 123
Query: 144 LVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQA----------EDPGDGQFVAANTPG 193
++ LV+CG QG C L ++ A P D A+ G
Sbjct: 124 VLDPALPALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHHNRPDDCPDCVASPLG 183
Query: 194 VATVGLVVPLPGRDLLLVARGLAGKLSAGVPP--LAIRQLAGSQPFSSEGLGRLVV--GD 249
VV VA L ++A P ++IR+L + G L V
Sbjct: 184 TRVT--VVEQGQASYFYVASSLDAAVAASFSPRSVSIRRLKADASGFAPGFVALSVLPKH 241
Query: 250 FSDYNNSYVGAFADARSAYFVFRRRGARAQ--AEYRSYVARVCLGDTNLYSYVEVPLAC- 306
Y+ YV +F YF+ + + + + +AR+ + L Y E+ L C
Sbjct: 242 LVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLSATEPELGDYRELVLDCR 301
Query: 307 --------------QGQGLIQAAFLAP---------------GTLLGVFAAGPR-----G 332
Q +++ A AP L GVF G G
Sbjct: 302 FAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLATELSIAEGQEVLFGVFVTGKDGGPGVG 361
Query: 333 TQAALCAFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPESYP 392
+ +CAFP+ L +++ C + G + S C P S
Sbjct: 362 PNSVVCAFPIDLLDTLIDEGVERCCESPVH--PGLRRGLDFFQSPSFCPNPPGLEALSPN 419
Query: 393 CGDEHTPSPIAGR-QPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGS 451
H P ++ +++ L V+A+ + D +A +G G++ +V L S
Sbjct: 420 TSCRHFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRLDNVTVAHMGTMDGRILQVELVRS 479
Query: 452 QGQVYH--SQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPV--AACPQFPDCASCL 507
+ + + +G G + D + G HL + QV ++P+ C F C CL
Sbjct: 480 LNYLLYVSNFSLGDSGQPVQRD--VSRLGDHLLFASGDQVFQVPIQGPGCRHFLTCGRCL 537
Query: 508 QAQDPL-CGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQ 566
+A + CGWC GQ + S+++D H L HP G
Sbjct: 538 RAWHFMGCGWC-----------GNMCGQQKECPGSWQQD----HCPPKLTEFHP--HSGP 580
Query: 567 VTLSVPRLPILDADEYFHCAFGDYDSLAHVEGPHVACVTPPQDQVPLNP-PGTDHV 621
+ S RL + ++ Y H + + V C P+D L P P D V
Sbjct: 581 LRGST-RLTLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFV 635
>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
Length = 1408
Score = 90.5 bits (223), Expect = 1e-17
Identities = 73/236 (30%), Positives = 102/236 (43%), Gaps = 12/236 (5%)
Query: 818 CSHCQAANRSLGCLWCADGQPACRYGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALT 877
CS C +A + C WC D C C G P+I V P + P EGG LT
Sbjct: 526 CSQCLSAPPFVQCGWCHD---KCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLT 582
Query: 878 ILGSNLG----RAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAI 933
I G + G F + V + + C S T + C PA N + + I
Sbjct: 583 ICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLS-ESTMNTLKCTVGPAMNKHFN-MSIII 640
Query: 934 KSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPIL 993
+ F+Y DPV+ S+SP++GP AGGT LT+ G +L +G + +GG+ C L
Sbjct: 641 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTC-TL 699
Query: 994 EPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASF 1049
+ V + C T Q E AV + A R S F Y +P + P+ SF
Sbjct: 700 KSVSNSILECYTPAQTISTEFAVKLKIDLANRE--TSIFSYREDPIVYEIHPTKSF 753
Score = 79.0 bits (193), Expect = 4e-14
Identities = 116/525 (22%), Positives = 205/525 (39%), Gaps = 119/525 (22%)
Query: 89 LYVGAVNRLFQLSPE-LQLEAVAVTGPVIDSPDCVPFRD---PAECPQAQLTDNANQLLL 144
+++GA N ++ L+ E LQ A TGPV++ PDC P +D A DN N L+
Sbjct: 62 IFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMALV 121
Query: 145 VSS-RAQELVACGQVRQGVCET-----RRLGDVAEVLY-----QAEDPGDGQFVAANTPG 193
V + +L++CG V +G C+ D+ ++ Q E+P + G
Sbjct: 122 VDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSALG 181
Query: 194 VATVGLVVPLPGRDLLL---VARGLAGKLSAGVP--PLAIRQLAGSQP---FSSEGLGRL 245
+ V +D + V + P +++R+L ++ F ++
Sbjct: 182 AKVLSSV-----KDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYID 236
Query: 246 VVGDFSD-YNNSYVGAFADARSAYFVFRRRGARAQAEYRSYVARVCLGDTNLYSYVEVPL 304
V+ +F D Y YV AF YF+ +R + + + R C ++ L+SY+E+PL
Sbjct: 237 VLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPL 296
Query: 305 AC-------------QGQGLIQAAFLA-PGT--------------LLGVFAAGPRGT--- 333
C + ++QAA+++ PG L GVFA +
Sbjct: 297 ECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEP 356
Query: 334 --QAALCAFPMVELG------ASMEQARRLCYTAGG-----------RGPSGAEEATVEY 374
++A+CAFP+ + + R L + G R SG E EY
Sbjct: 357 MDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEY 416
Query: 375 GVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQ----PVSAVAALQADG 430
+D L +GQ +++++
Sbjct: 417 RTEFTTALQRVD---------------------------LFMGQFSEVLLTSISTFIKGD 449
Query: 431 HMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLD---SSGSHLYVLTAH 487
IA LG ++G+ +V + S H + +SP+++++ + + V+T
Sbjct: 450 LTIANLGTSEGRFMQVVVSRSGPSTPHVNFL-LDSHPVSPEVIVEHTLNQNGYTLVITGK 508
Query: 488 QVDRIPV--AACPQFPDCASCLQAQDPL-CGWCVLQGRCTRKGQC 529
++ +IP+ C F C+ CL A + CGWC +C R +C
Sbjct: 509 KITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWC--HDKCVRSEEC 551
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 62.0 bits (149), Expect = 5e-09
Identities = 114/508 (22%), Positives = 181/508 (35%), Gaps = 112/508 (22%)
Query: 78 NHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVIDSPDCVPFRDPAECPQA---- 133
+ LAL P L VGA N LF+LS ++ + + D Q+
Sbjct: 127 SQLALDPSGNQLIVGARNYLFRLS--------LANVSLLQATEWASSEDTRRSCQSKGKT 178
Query: 134 -QLTDNANQLLLVSSRAQELVACG-QVRQGVCETRRLGDVAEVLYQAE-------DPGDG 184
+ N ++L+V+ R ++ CG +C +R++G+++ + + DP
Sbjct: 179 EEECQNYVRVLIVAGR--KVFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHN 236
Query: 185 QFVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSEGLGR 244
++ G V+ GRD + L +G PPL Q ++S+ L
Sbjct: 237 STAVISSQGELYAATVIDFSGRDPAIYR-----SLGSG-PPLRTAQ------YNSKWLNE 284
Query: 245 LVVGDFSDYNNSYVGAFADARSAYFVFRRRGARAQAEYRSY--VARVCLGDTN------- 295
++V A+ AYF R Y VARVC D
Sbjct: 285 ----------PNFVAAYDIGLFAYFFLRENAVEHDCGRTVYSRVARVCKNDVGGRFLLED 334
Query: 296 -LYSYVEVPLACQGQGLI-------QAAFLAP--GTLLGVFAAGPRGTQA-ALCAFPMVE 344
++++ L C G + Q+AF P + GVF A A+CAF +
Sbjct: 335 TWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSA 394
Query: 345 LGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSP-ESYPCGDEHTPSP-- 401
+ + GP Y R LP+ +P ++ CG P
Sbjct: 395 ISQAFN------------GP-------FRYQENPRAAWLPIANPIPNFQCGTLPETGPNE 435
Query: 402 -IAGRQPLEVQPLLKLG---QPVSAVAALQADG----HMIAFLGDTQGQLYKVFLHGSQ- 452
+ R + Q L + QPV+ + D H++ L + LY V G++
Sbjct: 436 NLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTES 495
Query: 453 ---------------GQVYHSQQVGPPGSAIS-PDLLLDSSGSHLYVLTAHQVDRIPVAA 496
G V PPG L + S L+V V R+P+
Sbjct: 496 GTILKALSTASRSLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLER 555
Query: 497 CPQFPDCASCLQAQDPLCGWCVLQGRCT 524
C + +CL A+DP CGW Q RC+
Sbjct: 556 CAAYRSQGACLGARDPYCGWDGKQQRCS 583
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 61.2 bits (147), Expect = 9e-09
Identities = 124/503 (24%), Positives = 187/503 (37%), Gaps = 69/503 (13%)
Query: 80 LALAPGRGTLYVGAVNRLFQLSPE-LQLE-AVAVTGPVIDSPDCVPFRDPAECPQAQLTD 137
L L G LYVGA LF S E L+L+ A++ PV +C+ + + T+
Sbjct: 56 LTLTEPTGLLYVGAREALFAFSMEALELQGAISWEAPVEKKTECI------QKGKNNQTE 109
Query: 138 NANQL-LLVSSRAQELVACGQVR-QGVCETRRLGDVAEVLYQAEDPGDGQFVAANTPGVA 195
N + L A L CG Q C + + L E DG+ P
Sbjct: 110 CFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNM--LTFTLEHGEFE-DGKGKCPYDPAKG 166
Query: 196 TVGLVVPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSEGLGRLV-----VGDF 250
GL+V D L + L L G P+ +R + +E L + VG
Sbjct: 167 HAGLLV-----DGELYSATLNNFL--GTEPIILRNMGPHHSMKTEYLAFWLNEPHFVG-- 217
Query: 251 SDYNNSYVGAFA-DARSAYFVFRRRGARAQA---EYRSYVARVCLGDTN--------LYS 298
S Y VG+F D YF FR R + + + VARVC GD +
Sbjct: 218 SAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQRKWTT 277
Query: 299 YVEVPLAC------------QGQGLIQAAFLAPGTLLGVFAAGPRGTQ-AALCAFPMVEL 345
+++ LAC Q +Q T GVF A +A+C + + E+
Sbjct: 278 FLKARLACSAPNWQLYFNQLQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEI 337
Query: 346 GASMEQARRLCYTAGGRG-------PSGAEEATVEYGVTSRCVTLPLDSPESYPCGDEHT 398
E + + + PS + + T L+ P++ +
Sbjct: 338 QRVFEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKH 397
Query: 399 PSPIAGRQPLEVQPLL-KLGQPVSAVAALQADG-----HMIAFLGDTQGQLYKVFLHGSQ 452
P P +PLL K G + + A + G + + F+G G L K G
Sbjct: 398 PLMEEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAVSLGPW 457
Query: 453 GQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDP 512
+ Q+ S L+L S L+ + Q+ ++PVA C ++ CA C+ A+DP
Sbjct: 458 VHLIEELQLFDQEPMRS--LVLSQSKKLLFAGSRSQLVQLPVADCMKYRSCADCVLARDP 515
Query: 513 LCGWCVLQGRCTRKGQCGRAGQL 535
C W V RC G G +G L
Sbjct: 516 YCAWSVNTSRCVAVG--GHSGSL 536
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 57.8 bits (138), Expect = 1e-07
Identities = 82/351 (23%), Positives = 140/351 (39%), Gaps = 53/351 (15%)
Query: 222 GVPPLAIRQLAGSQP-FSSEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARA-- 278
G P+ +R L GSQP ++ R + ++ S+V A + YF F +
Sbjct: 203 GSEPILMRTL-GSQPVLKTDNFLRWL-----HHDASFVAAIPSTQVVYFFFEETASEFDF 256
Query: 279 -QAEYRSYVARVCLGDTN--------LYSYVEVPLACQGQG-----LIQAAFLAPGT--- 321
+ + S VARVC D ++++ L C G +I+ A L P
Sbjct: 257 FERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQLPFNVIRHAVLLPADSPT 316
Query: 322 ---LLGVFAAGPR--GTQA-ALCAFPMVEL-----GASMEQARRLCYTAGGRGP-SGAEE 369
+ VF + + GT++ A+CAF ++++ G E + RGP +
Sbjct: 317 APHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRP 376
Query: 370 ATVEYGVTS-RCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPVSAVAALQA 428
+ G +S + +T D + ++ +P+ + +E L V L
Sbjct: 377 GSCSVGPSSDKALTFMKDH---FLMDEQVVGTPLLVKSGVEYTRLA-----VETAQGLDG 428
Query: 429 DGHMIAFLGDTQGQLYKVFLHG-SQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAH 487
H++ +LG T G L+K + G S + Q+ P + L + G+ ++V +
Sbjct: 429 HSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGA-VFVGFSG 487
Query: 488 QVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQW 538
V R+P A C + C C+ A+DP C W C A LN W
Sbjct: 488 GVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLS----APNLNSW 534
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 54.7 bits (130), Expect = 9e-07
Identities = 114/516 (22%), Positives = 184/516 (35%), Gaps = 112/516 (21%)
Query: 70 FSAPNTT-LNHLALAPGRGTLYVGAVNRLFQLSPELQLEAVAVTGPVI-DSPDCVPFRDP 127
F A N + L PG+ L VGA N LF+L QLE +++ V + +
Sbjct: 50 FRAKNAVDFSQLTFDPGQKELVVGARNYLFRL----QLEDLSLIQAVEWECDEATKKACY 105
Query: 128 AECPQAQLTDNANQLLLVSSRAQELVACG-QVRQGVCETRRLGDVAEVLYQAE------- 179
++ + N ++LLV L CG VC R L ++ E+ Q
Sbjct: 106 SKGKSKEECQNYIRVLLVGG--DRLFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPY 163
Query: 180 DPGDGQFVAANTPGVATVGLVVPLPGRDLLLVARGLAGKLSAGV-PPLAIRQLAGSQPFS 238
P G + PGRD + S G+ PPL Q ++
Sbjct: 164 SPQHNSTALLTAGGELYAATAMDFPGRDPAIYR-------SLGILPPLRTAQ------YN 210
Query: 239 SEGLGRLVVGDFSDYNNSYVGAFADARSAYFVFRRRGARAQAEYR--SYVARVCLGDTN- 295
S+ L ++V ++ YF FR S ARVC D
Sbjct: 211 SKWLNE----------PNFVSSYDIGNFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGG 260
Query: 296 -------LYSYVEVPLACQGQGLI-------QAAFLAP--GTLLGVFAAGPRGTQA-ALC 338
++++ L C G + Q+ F P + G+F A A+C
Sbjct: 261 RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPELDLIYGIFTTNVNSIAASAVC 320
Query: 339 AFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRCVTLPLDSPES-YPCG--D 395
F + + + GP +Y SR LP +P + CG D
Sbjct: 321 VFNLSAIAQAFS------------GP-------FKYQENSRSAWLPYPNPNPHFQCGTVD 361
Query: 396 EHTPSPIAGRQPLEVQPLL---KLGQPVSAVAALQADGHMIAFLGD--TQGQ---LYKVF 447
+ + R + Q + ++ QPV+ V + D + + QG+ ++ ++
Sbjct: 362 QGLYVNLTERNLQDAQKFILMHEVVQPVTTVPSFMEDNSRFSHVAVDVVQGREALVHIIY 421
Query: 448 LHGSQGQVYHSQQVGPPGSAISPDLLLDS-------------------SGSHLYVLTAHQ 488
L G + ++V P + S LL+ S S L+V
Sbjct: 422 LATDYGTI---KKVRVPLNQTSSSCLLEEIELFPERRREPIRSLQILHSQSVLFVGLREH 478
Query: 489 VDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCT 524
V +IP+ C + ++C+ AQDP CGW V+ +CT
Sbjct: 479 VVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMKKCT 514
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 53.9 bits (128), Expect = 1e-06
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 433 IAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRI 492
+ FLG G+L+K G + + Q+ G + +LLLD+ LY + V ++
Sbjct: 463 VLFLGTGDGRLHKAVSVGPRVHIIEELQIFSSGQPVQ-NLLLDTHRGLLYAASHSGVVQV 521
Query: 493 PVAACPQFPDCASCLQAQDPLCGW 516
P+A C + C CL A+DP C W
Sbjct: 522 PMANCSLYRSCGDCLLARDPYCAW 545
Score = 36.6 bits (83), Expect = 0.24
Identities = 37/90 (41%), Positives = 41/90 (45%), Gaps = 19/90 (21%)
Query: 33 RPWL--PKAPVMARWPPFGLCLLLLLLSPPP----------LPLTGAH----RFSAPNTT 76
R WL P + R P L LLLLLL PPP LPL RF A + +
Sbjct: 9 RSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHIS 68
Query: 77 LNHLALAPGRG--TLYVGAVNRLFQLSPEL 104
N+ AL R TLYVGA LF LS L
Sbjct: 69 -NYTALLLSRDGRTLYVGAREALFALSSNL 97
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 53.9 bits (128), Expect = 1e-06
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 433 IAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRI 492
+ FLG G+L+K G + + Q+ G + +LLLD+ LY + V ++
Sbjct: 463 VLFLGTGDGRLHKAVSVGPRVHIIEELQIFSSGQPVQ-NLLLDTHRGLLYAASHSGVVQV 521
Query: 493 PVAACPQFPDCASCLQAQDPLCGW 516
P+A C + C CL A+DP C W
Sbjct: 522 PMANCSLYRSCGDCLLARDPYCAW 545
Score = 36.6 bits (83), Expect = 0.24
Identities = 37/90 (41%), Positives = 41/90 (45%), Gaps = 19/90 (21%)
Query: 33 RPWL--PKAPVMARWPPFGLCLLLLLLSPPP----------LPLTGAH----RFSAPNTT 76
R WL P + R P L LLLLLL PPP LPL RF A + +
Sbjct: 9 RSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTWALSPRISLPLGSEERPFLRFEAEHIS 68
Query: 77 LNHLALAPGRG--TLYVGAVNRLFQLSPEL 104
N+ AL R TLYVGA LF LS L
Sbjct: 69 -NYTALLLSRDGRTLYVGAREALFALSSNL 97
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 52.4 bits (124), Expect = 4e-06
Identities = 68/288 (23%), Positives = 107/288 (37%), Gaps = 57/288 (19%)
Query: 284 SYVARVCLGDTN---------LYSYVEVPLACQGQGLIQAAFLAPGTLLGVFAAGPRGTQ 334
S VARVC D S+++ L C G F + GV + G R
Sbjct: 261 SRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPVV 320
Query: 335 -------------AALCAFPMVELGASME------QARRLCYTAGGRG------PSGAEE 369
+A+CAF + ++ A E ++ +T P
Sbjct: 321 LAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAA 380
Query: 370 ATVEYGVTSRCVTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLK--LGQPVSAVAALQ 427
++Y +S L+ +++P DE PS G P ++ L++ L + V A
Sbjct: 381 PGMQYNASSALPDDILNFVKTHPLMDEAVPS--LGHAPWILRTLMRHQLTRVAVDVGAGP 438
Query: 428 ADGHMIAFLGDTQGQLYKVFLH------GSQG--------QVYHSQQVGPPGSAISPDLL 473
+ FLG G + K + G+ G + Y + G PG + L
Sbjct: 439 WGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGETGQRL 498
Query: 474 L----DSSGSHLYVLTAHQVDRIPVAACPQFPDCA-SCLQAQDPLCGW 516
L D++ L V R+PVA C Q+ C +C+ +QDP CGW
Sbjct: 499 LSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGW 546
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 51.6 bits (122), Expect = 7e-06
Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 417 GQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDS 476
G PV+ A D + FLG G ++K + GS + QV ++ +L++
Sbjct: 432 GTPVTTPAGPTYD---LLFLGTADGWIHKAVVLGSGMHIIEETQVFRESQSVE-NLVISL 487
Query: 477 SGSHLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGW 516
LYV V ++P+++C ++ C C+ A+DP CGW
Sbjct: 488 LQHSLYVGAPSGVIQLPLSSCSRYRSCYDCILARDPYCGW 527
>gi|126116589 fibrocystin L [Homo sapiens]
Length = 4243
Score = 51.2 bits (121), Expect = 1e-05
Identities = 91/402 (22%), Positives = 140/402 (34%), Gaps = 51/402 (12%)
Query: 872 GGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRV 931
G + + I G LG D+ AV + ++ ++ I + +P P G V V
Sbjct: 1761 GSVKVLIEGEGLGTVLEDI--AVFIGNQQFR---AIEVNENNITALVTPLPVGHHS-VSV 1814
Query: 932 AIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCP 991
+ S+ G++ + T P + SLSP G GGT L I G GNT+ +G +PC
Sbjct: 1815 VVGSK--GLALGNLTVSSPPVASLSPTSGSIGGGTTLVITGNGFYP-GNTTVTIGDEPCQ 1871
Query: 992 ILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRG 1051
I+ + P + CRT P G V + L + P L PS G
Sbjct: 1872 IIS-INPNEVYCRT-PAGTTGMVDVKIFVNTIAYPPLLFTYALEDTPFLRGIIPSRGPPG 1929
Query: 1052 GGRLIRVRGTGLDVVQRPLL------SVWLEADAEVQ---ASRAQPQDPQPRRSCGAPAA 1102
I G ++++ ++ +V + D+ VQ A P +A
Sbjct: 1930 TEIEITGSNFGFEILEISVMINNIQCNVTMANDSVVQCIVGDHAGGTFPVMMHHKTKGSA 1989
Query: 1103 DPQACIQ--------------LGGGLLQCSTVCSVN--SSSLLLCRSPAVPDRAHPQRVF 1146
+ GGG T N +S +L+C S DR
Sbjct: 1990 MSTVVFEYPLNIQNINPSQGSFGGGQTMTVTGTGFNPQNSIILVCGSECAIDRLRSDYTT 2049
Query: 1147 FTLD--------NVQVDFASASGGQGFLYQPNP-----RLAPLSREGPARPYRLKPGHVL 1193
+ Q S G+ P L PL + G L
Sbjct: 2050 LLCEIPSNNGTGAEQACEVSVVNGKDLSQSMTPFTYAVSLTPLITAVSPKRGSTAGGTRL 2109
Query: 1194 DVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAH 1235
V G G + + E+V + I +C V+ +TH+ C AH
Sbjct: 2110 TVVGSGFSENM--EDVHITIAEAKCDVEYSNKTHIICMTDAH 2149
Score = 45.8 bits (107), Expect = 4e-04
Identities = 60/249 (24%), Positives = 99/249 (39%), Gaps = 20/249 (8%)
Query: 842 YGPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPC 901
Y PL A+E P + + P GPP G + I GSN G F ++ +V + + C
Sbjct: 1903 YPPLLFTYALE---DTPFLRGIIPSRGPP--GTEIEITGSNFG--FEILEISVMINNIQC 1955
Query: 902 NPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPPGISSQHFTYQDPV-LLSLSPRWG 960
N + + + C+ GT PV + K++ +S+ F Y P+ + +++P G
Sbjct: 1956 NVTMA---NDSVVQCIVGDHAGGTF-PVMMHHKTKGSAMSTVVFEY--PLNIQNINPSQG 2009
Query: 961 PQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCP-EAIVCRTRPQAAPG--EAAVL 1017
GG +T+ G N+ V G C I ++C G +A +
Sbjct: 2010 SFGGGQTMTVTGTGFNPQ-NSIILVCGSECAIDRLRSDYTTLLCEIPSNNGTGAEQACEV 2068
Query: 1018 VVFGHAQRTLLASPFRYTAN--PQLVAAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWL 1075
V + +PF Y + P + A P GG + V G+G +
Sbjct: 2069 SVVNGKDLSQSMTPFTYAVSLTPLITAVSPKRGSTAGGTRLTVVGSGFSENMEDVHITIA 2128
Query: 1076 EADAEVQAS 1084
EA +V+ S
Sbjct: 2129 EAKCDVEYS 2137
Score = 44.7 bits (104), Expect = 9e-04
Identities = 50/175 (28%), Positives = 70/175 (40%), Gaps = 20/175 (11%)
Query: 858 PSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCV 917
P + A+ P G E G LTI+GS + A VSV C+ L + C
Sbjct: 1067 PLVLAISPSQGSYEEGTILTIVGSGFSPSSA---VTVSVGPVGCS---LLSVDEKELKC- 1119
Query: 918 TSPAPNGTTGPVRVAIKSQPPGISSQ------HFTYQDPVLLSLSPRWGPQAGGTQLTIR 971
NG+ G VA+ G++ +F YQ + + P G AGGT LT+
Sbjct: 1120 --QILNGSAGHAPVAVSMADVGLAQNVGGEEFYFVYQSQI-SHIWPDSGSIAGGTLLTLS 1176
Query: 972 GQHLQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRT 1026
G N+ VG + C ++E I CRT P+ G + V Q T
Sbjct: 1177 G--FGFNENSKVLVGNETCNVIEGDL-NRITCRT-PKKTEGTVDISVTTNGFQAT 1227
Score = 43.5 bits (101), Expect = 0.002
Identities = 57/217 (26%), Positives = 89/217 (41%), Gaps = 25/217 (11%)
Query: 860 IDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTS 919
I + P +G GG LT+ G V V + CN + RI C T
Sbjct: 1157 ISHIWPDSGSIAGGTLLTLSGFGFNE-----NSKVLVGNETCNV---IEGDLNRITCRT- 1207
Query: 920 PAPNGTTGPVRVAIKSQP-PGISSQHFTY---QDPVLLSLSPRWGPQAGGTQLTIRGQHL 975
P T G V +++ + + F+Y Q P++ SP+ G LTI+G +
Sbjct: 1208 --PKKTEGTVDISVTTNGFQATARDAFSYNCLQTPIITDFSPKVRTILGEVNLTIKGYNF 1265
Query: 976 --QTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQAAPGEAAVLVV---FGHAQ-RTLLA 1029
+ N + +VGG+ C IL + I C P+ +PG+ + V +G A R L
Sbjct: 1266 GNELTQNMAVYVGGKTCQILHWNFTD-IRC-LLPKLSPGKHDIYVEVRNWGFASTRDKLN 1323
Query: 1030 SPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVV 1066
S +Y ++ + P GG I +RG G +
Sbjct: 1324 SSIQYVL--EVTSMFPQRGSLFGGTEITIRGFGFSTI 1358
Score = 42.7 bits (99), Expect = 0.003
Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 12/121 (9%)
Query: 858 PSIDAVEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCV 917
P I AV P G GG LT++GS DV +++A C+ E Y I+C+
Sbjct: 2091 PLITAVSPKRGSTAGGTRLTVVGSGFSENMEDVH--ITIAEAKCDVE---YSNKTHIICM 2145
Query: 918 TSPAPNGTTGPVRVAIKSQPPG-ISSQHFTYQDPVLLSLSPRWG----PQAGGTQLTIRG 972
T PV V I+ + + F Y D + S WG P+ G + +G
Sbjct: 2146 TDAHTLSGWAPVCVHIRGVGMAKLDNADFLYVDAWSSNFS--WGGKSPPEEGSLVVITKG 2203
Query: 973 Q 973
Q
Sbjct: 2204 Q 2204
Score = 38.1 bits (87), Expect = 0.084
Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Query: 957 PRWGPQAGGTQLTIRGQHL-QTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQ 1008
P G GGT LTI G+ QT VGG+PC IL V +I C+T P+
Sbjct: 277 PSQGSIRGGTTLTISGRFFDQTDFPVRVLVGGEPCDILN-VTENSICCKTPPK 328
Score = 33.1 bits (74), Expect = 2.7
Identities = 30/117 (25%), Positives = 48/117 (41%), Gaps = 4/117 (3%)
Query: 950 PVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGGQPCPILEPVCPEAIVCRTRPQA 1009
P++L++SP G GT LTI G + VG C +L V + + C+ +
Sbjct: 1067 PLVLAISPSQGSYEEGTILTIVGSGFSPSSAVTVSVGPVGCSLLS-VDEKELKCQILNGS 1125
Query: 1010 APGEAAVLVVFGHA--QRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLD 1064
A G A V V + + F + Q+ P + GG L+ + G G +
Sbjct: 1126 A-GHAPVAVSMADVGLAQNVGGEEFYFVYQSQISHIWPDSGSIAGGTLLTLSGFGFN 1181
Score = 32.3 bits (72), Expect = 4.6
Identities = 44/177 (24%), Positives = 65/177 (36%), Gaps = 43/177 (24%)
Query: 858 PSIDAVEPLTGPPEGGLALTILGSNLGRAFA------------DVQYAVSVASRPCNPEP 905
P + + P G G LTI G +A VQ S S C+ E
Sbjct: 31 PKVTEIIPKYGSINGATRLTIRGEGFSQANQFNYGVDNAELGNSVQLISSFQSITCDVEK 90
Query: 906 SLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPPG--------ISSQHFTY-----QDPVL 952
S +I C T P + VRV++ P I+S T+ + P +
Sbjct: 91 DASH-STQITCYTRAMPEDSY-TVRVSVDGVPVTENNTCKGHINSWECTFNAKSFRTPTI 148
Query: 953 LSLSPRWGPQAGGTQLTIRGQ----------HLQTGGNT----SAFVGGQPCPILEP 995
S++P G GT +TI+G+ L + G ++GG PC +L P
Sbjct: 149 RSITPLSGTP--GTLITIQGRIFTDVYGSNIALSSNGKNVRILRVYIGGMPCELLIP 203
>gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic
domain, (semaphorin) 6A [Homo sapiens]
Length = 1030
Score = 48.5 bits (114), Expect = 6e-05
Identities = 40/151 (26%), Positives = 65/151 (43%), Gaps = 15/151 (9%)
Query: 389 ESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKV-- 446
+++P DE PS L +L + AA H + FLG +G + K
Sbjct: 393 KTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLA 452
Query: 447 ------FLHGS----QGQVYHSQQVGPPGSAISP--DLLLDSSGSHLYVLTAHQVDRIPV 494
FL+ S + VY+S++ G + LD + S LYV + V ++P+
Sbjct: 453 RIGNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPL 512
Query: 495 AACPQFPDCA-SCLQAQDPLCGWCVLQGRCT 524
C + C +C+ ++DP CGW G C+
Sbjct: 513 GRCERHGKCKKTCIASRDPYCGWIKEGGACS 543
>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
Length = 666
Score = 47.4 bits (111), Expect = 1e-04
Identities = 44/163 (26%), Positives = 72/163 (44%), Gaps = 26/163 (15%)
Query: 385 LDSPESYPCGDEHTPSP-----IAGRQP---LEVQPLLKLGQPVS---------AVAALQ 427
L +P C + P P +A R P V+P+ L P+ AV +Q
Sbjct: 358 LPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQ 417
Query: 428 A---DGHMIAFLGDTQGQLYKVFLHGSQGQ--VYHSQQVGP-PGSAISPDLLLDSSGSHL 481
A + + +L +G ++KV G Q ++ ++ P +A + LD+ L
Sbjct: 418 ASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKL 477
Query: 482 YVLTAHQVDRIPVAACPQFPD-CASCLQAQDPLCGWCVLQGRC 523
YV + +V ++P+ C + C CL ++DP CGW QGRC
Sbjct: 478 YVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWD--QGRC 518
>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
Length = 501
Score = 47.4 bits (111), Expect = 1e-04
Identities = 44/163 (26%), Positives = 72/163 (44%), Gaps = 26/163 (15%)
Query: 385 LDSPESYPCGDEHTPSP-----IAGRQP---LEVQPLLKLGQPVS---------AVAALQ 427
L +P C + P P +A R P V+P+ L P+ AV +Q
Sbjct: 193 LPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQ 252
Query: 428 A---DGHMIAFLGDTQGQLYKVFLHGSQGQ--VYHSQQVGP-PGSAISPDLLLDSSGSHL 481
A + + +L +G ++KV G Q ++ ++ P +A + LD+ L
Sbjct: 253 ASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKL 312
Query: 482 YVLTAHQVDRIPVAACPQFPD-CASCLQAQDPLCGWCVLQGRC 523
YV + +V ++P+ C + C CL ++DP CGW QGRC
Sbjct: 313 YVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWD--QGRC 353
>gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]
Length = 652
Score = 47.4 bits (111), Expect = 1e-04
Identities = 44/163 (26%), Positives = 72/163 (44%), Gaps = 26/163 (15%)
Query: 385 LDSPESYPCGDEHTPSP-----IAGRQP---LEVQPLLKLGQPVS---------AVAALQ 427
L +P C + P P +A R P V+P+ L P+ AV +Q
Sbjct: 344 LPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQ 403
Query: 428 A---DGHMIAFLGDTQGQLYKVFLHGSQGQ--VYHSQQVGP-PGSAISPDLLLDSSGSHL 481
A + + +L +G ++KV G Q ++ ++ P +A + LD+ L
Sbjct: 404 ASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKL 463
Query: 482 YVLTAHQVDRIPVAACPQFPD-CASCLQAQDPLCGWCVLQGRC 523
YV + +V ++P+ C + C CL ++DP CGW QGRC
Sbjct: 464 YVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWD--QGRC 504
>gi|19923279 semaphorin W [Homo sapiens]
Length = 770
Score = 45.8 bits (107), Expect = 4e-04
Identities = 124/559 (22%), Positives = 191/559 (34%), Gaps = 120/559 (21%)
Query: 47 PFGLCLLLLLLSP-----------PPLPLTGAH----RFSAPNT-TLNHLALAPGRGTLY 90
PF L LL +L P LP++ A RF+ P+T + L + P TLY
Sbjct: 19 PFPLLLLAVLSGPVSGRVPRSVPRTSLPISEADSCLTRFAVPHTYNYSVLLVDPASHTLY 78
Query: 91 VGAVNRLFQLSPELQLEA---VAVTGPVIDSPDC-VPFRDPAECPQAQLTDNANQLLLVS 146
VGA + +F LS E + P +C + EC N Q+L ++
Sbjct: 79 VGARDTIFALSLPFSGERPRRIDWMVPEAHRQNCRKKGKKEDEC------HNFVQILAIA 132
Query: 147 SRAQELVACGQV----RQGVCETRRLGDVAEVLYQAEDPGDGQ--FVAANTPGVATVGLV 200
+ A L+ CG + GV + R V + + G G+ F A G
Sbjct: 133 N-ASHLLTCGTFAFDPKCGVIDVSRFQQVERL-----ESGRGKCPFEPAQRSAAVMAG-- 184
Query: 201 VPLPGRDLLLVARGLAGKLSAGVPPLAIRQLAGSQPFSSEGLGRLVVGDFSDYNNSYVGA 260
G L A ++ G++P + +GR +D S++ A
Sbjct: 185 ----------------GVLYAAT----VKNYLGTEPIITRAVGRAEDWIRTDTLPSWLNA 224
Query: 261 FA---------------DARSAYFVFRRRGARAQAEYRSY----VARVCLGDTN------ 295
A D + F +RA Y VARVC GD
Sbjct: 225 PAFVAAVALSPAEWGDEDGDDEIYFFFTETSRAFDSYERIKVPRVARVCAGDLGGRKTLQ 284
Query: 296 --LYSYVEVPLACQGQG-------LIQAAFLAP----GTLL--GVFAAGPRG-TQAALCA 339
++++ L C G L A L P GT + G+F++ G T +A+CA
Sbjct: 285 QRWTTFLKADLLCPGPEHGRASSVLQDVAVLRPELGAGTPIFYGIFSSQWEGATISAVCA 344
Query: 340 FPMVELGASMEQARRLCYTAGGRG--------PSGAEEATVEYGVTSRCVTLPLDSPE-- 389
F ++ + R RG P + + R L P+
Sbjct: 345 FRPQDIRTVLNGPFRELKHDCNRGLPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRV 404
Query: 390 -----SYPCGDEHTPSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLY 444
+P D P G L L V +L + + +LG G L+
Sbjct: 405 LTFIRDHPLMDRPV-FPADGHPLLVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLH 463
Query: 445 KVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGSHLYVLTAHQVDRIPVAACPQFPDCA 504
+ G+Q V + P + L S L V + +V ++ C + C+
Sbjct: 464 RAVRIGAQLSVLEDLALFPEPQPVENMKLYHS---WLLVGSRTEVTQVNTTNCGRLQSCS 520
Query: 505 SCLQAQDPLCGWCVLQGRC 523
C+ AQDP+C W C
Sbjct: 521 ECILAQDPVCAWSFRLDEC 539
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,038,305
Number of Sequences: 37866
Number of extensions: 4488797
Number of successful extensions: 12536
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 12058
Number of HSP's gapped (non-prelim): 254
length of query: 1932
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1815
effective length of database: 13,817,196
effective search space: 25078210740
effective search space used: 25078210740
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.