Guide to the Human Genome
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Name: FLT3 Sequence: fasta or formatted (993aa) NCBI GI: 121114304
Description:

fms-related tyrosine kinase 3

Referenced in:

Hematopoiesis and Erythrocytes
Receptor Tyrosine Kinases
Kruppel-related Zinc Finger Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.2         52           3
 C cysteine            3.3         33           2
 D aspartate           4.2         42           2
 E glutamate           7.8         77           4
 F phenylalanine       5.8         58           1
 G glycine             5.4         54           2
 H histidine           2.1         21           1
 I isoleucine          5.2         52           2
 K lysine              5.3         53           2
 L leucine             8.8         87           2
 M methionine          2.4         24           2
 N asparagine          5.0         50           2
 P proline             4.3         43           1
 Q glutamine           4.2         42           1
 R arginine            4.2         42           2
 S serine              9.1         90           3
 T threonine           5.1         51           2
 V valine              6.6         66           2
 W tryptophan          1.5         15           1
 Y tyrosine            4.1         41           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   fms-related tyrosine kinase 3 
KIT                   0.214   v-kit Hardy-Zuckerman 4 feline sarcoma viral oncoge...
KIT                   0.213   v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene...
CSF1R                 0.208   colony stimulating factor 1 receptor precursor [Homo...
PDGFRA                0.198   platelet-derived growth factor receptor alpha precurs...
PDGFRB                0.186   platelet-derived growth factor receptor beta precurso...
FLT1                  0.156   fms-related tyrosine kinase 1 isoform 1 precursor [...
KDR                   0.152   kinase insert domain receptor precursor 
FLT4                  0.150   fms-related tyrosine kinase 4 isoform 1 precursor [...
FLT4                  0.150   fms-related tyrosine kinase 4 isoform 2 precursor [...
FGFR2                 0.130   fibroblast growth factor receptor 2 isoform 8 precu...
FGFR2                 0.129   fibroblast growth factor receptor 2 isoform 6 precu...
FGFR2                 0.129   fibroblast growth factor receptor 2 isoform 4 precu...
FGFR2                 0.129   fibroblast growth factor receptor 2 isoform 1 precu...
FGFR2                 0.128   fibroblast growth factor receptor 2 isoform 5 precu...
FGFR2                 0.128   fibroblast growth factor receptor 2 isoform 2 precu...
FGFR2                 0.127   fibroblast growth factor receptor 2 isoform 7 precu...
FGFR2                 0.126   fibroblast growth factor receptor 2 isoform 9 precu...
FGFR2                 0.126   fibroblast growth factor receptor 2 isoform 3 precu...
RET                   0.114   ret proto-oncogene isoform c 
RET                   0.114   ret proto-oncogene isoform a 
FGFR3                 0.084   fibroblast growth factor receptor 3 isoform 3 precu...
FGFR3                 0.084   fibroblast growth factor receptor 3 isoform 2 precur...
FGFR3                 0.084   fibroblast growth factor receptor 3 isoform 1 precurs...
FGFR1                 0.082   fibroblast growth factor receptor 1 isoform 4 precur...
FGFR1                 0.082   fibroblast growth factor receptor 1 isoform 3 precur...
FGFR1                 0.082   fibroblast growth factor receptor 1 isoform 2 precur...
FGFR1                 0.082   fibroblast growth factor receptor 1 isoform 1 precu...
TIE1                  0.080   tyrosine kinase with immunoglobulin-like and EGF-like...
FGFR4                 0.078   fibroblast growth factor receptor 4 isoform 2 precur...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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