Search of human proteins with 24497583

Search of human proteins with 24497583

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24497583 aldo-keto reductase family 1, member C3 [Homo
sapiens]
         (323 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]    660   0.0  
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]     585   e-167
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]    579   e-165
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]     579   e-165
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]    558   e-159
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]     384   e-107
gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]     315   5e-86
gi|223468663 aldo-keto reductase family 1, member B10 [Homo sapi...   298   6e-81
gi|122937516 aldo-keto reductase family 1, member B10-like [Homo...   286   2e-77
gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo ...   264   9e-71
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]    257   1e-68
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]     257   1e-68
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]         222   3e-58
gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s...    51   2e-06
gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s...    51   2e-06
gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]     46   5e-05
gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]     41   0.002
gi|27436964 potassium voltage-gated channel, shaker-related subf...    39   0.006
gi|27436962 potassium voltage-gated channel, shaker-related subf...    39   0.006
gi|27436966 potassium voltage-gated channel, shaker-related subf...    39   0.006
gi|4504825 potassium voltage-gated channel, shaker-related subfa...    34   0.20 
gi|27436969 potassium voltage-gated channel, shaker-related subf...    34   0.20 
gi|27436971 potassium voltage-gated channel, shaker-related subf...    31   1.3  
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    31   1.7  
gi|154354966 inner membrane protein, mitochondrial isoform 3 [Ho...    30   2.9  
gi|154354962 inner membrane protein, mitochondrial isoform 2 [Ho...    30   2.9  
gi|154354964 inner membrane protein, mitochondrial isoform 1 [Ho...    30   2.9  

>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
          Length = 323

 Score =  660 bits (1702), Expect = 0.0
 Identities = 323/323 (100%), Positives = 323/323 (100%)

Query: 1   MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60
           MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
Sbjct: 1   MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
           VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
           SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 301 RNLHYFNSDSFASHPNYPYSDEY 323
           RNLHYFNSDSFASHPNYPYSDEY
Sbjct: 301 RNLHYFNSDSFASHPNYPYSDEY 323


>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
          Length = 323

 Score =  585 bits (1508), Expect = e-167
 Identities = 284/323 (87%), Positives = 300/323 (92%)

Query: 1   MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60
           MDSK+QCVKLNDGHFMPVLGFGTYAP EVP+SKALE TKLAIEAGFRHIDSAHLYNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
           VGLAIRSKIADGSVKREDIFYTSKLW   HRPELVRPALE SLK  QLDYVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
           S+KPGEE+ P DENGK++FD VDLC TWEA+EKCKDAGLAKSIGVSNFNRRQLEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFN+ KLLDFCKSKDIVLVAYSALGS R++ WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT+E+MKAIDGL+
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNLHYFNSDSFASHPNYPYSDEY 323
           RN+ Y   D FA  PNYP+SDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  579 bits (1492), Expect = e-165
 Identities = 281/323 (86%), Positives = 297/323 (91%)

Query: 1   MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60
           MDSK+QCVKLNDGHFMPVLGFGTYAP EVP+SKALE  KLAIEAGF HIDSAH+YNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
           VGLAIRSKIADGSVKREDIFYTSKLWS  HRPELVRPALE SLK  QLDYVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
           S+KPGEE+ P DENGK++FD VDLC TWEAMEKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFN+ KLLDFCKSKDIVLVAYSALGS R++ WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT+E+MKAIDGL+
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNLHYFNSDSFASHPNYPYSDEY 323
           RN+ Y   D FA  PNYP+SDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  579 bits (1492), Expect = e-165
 Identities = 281/323 (86%), Positives = 297/323 (91%)

Query: 1   MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60
           MDSK+QCVKLNDGHFMPVLGFGTYAP EVP+SKALE  KLAIEAGF HIDSAH+YNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
           VGLAIRSKIADGSVKREDIFYTSKLWS  HRPELVRPALE SLK  QLDYVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
           S+KPGEE+ P DENGK++FD VDLC TWEAMEKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFN+ KLLDFCKSKDIVLVAYSALGS R++ WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT+E+MKAIDGL+
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNLHYFNSDSFASHPNYPYSDEY 323
           RN+ Y   D FA  PNYP+SDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
          Length = 323

 Score =  558 bits (1437), Expect = e-159
 Identities = 271/323 (83%), Positives = 295/323 (91%)

Query: 1   MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60
           MD K+Q V+LNDGHFMPVLGFGTYAPPEVPR++A+EVTKLAIEAGFRHIDSA+LYNNEEQ
Sbjct: 1   MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
           VGLAIRSKIADGSVKREDIFYTSKLW TF +P++V+PALE+SLKK QLDYVDLYL+H PM
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120

Query: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
           +LKPGE   P DENGKVIFD VDL  TWE MEKCKDAGLAKSIGVSNFN RQLEMILNKP
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPY N+SKLLDFCKSKDIVLVA+SALG+QR K WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300
           LCALAKKHK+TPALIALRYQLQRGVVVLAKSYNEQRIR+N+QVFEFQLT+EDMK +DGL+
Sbjct: 241 LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300

Query: 301 RNLHYFNSDSFASHPNYPYSDEY 323
           RN  Y   D    HP+YP+SDEY
Sbjct: 301 RNYRYVVMDFLMDHPDYPFSDEY 323


>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
          Length = 326

 Score =  384 bits (985), Expect = e-107
 Identities = 178/317 (56%), Positives = 239/317 (75%), Gaps = 1/317 (0%)

Query: 8   VKLNDGHFMPVLGFGTYAPPE-VPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
           + L+DG+ +P++G GTY+ P+  P+       K+AI+ G+RHID A++Y NE +VG AIR
Sbjct: 10  IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69

Query: 67  SKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
            KIA+G V+REDIFY  KLW+T H PE+VRP LE +L+  QLDYVDLY+I  PM+ KPG+
Sbjct: 70  EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129

Query: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
           E+ P DENGK ++   +LC TWEAME CKDAGL KS+GVSNFNRRQLE+ILNKPGLK+KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189

Query: 187 VCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAK 246
           V NQVECHPYF + KLL FC+  DIV+ AYS LG+ R+  WV+ +SP LL+D +L +L K
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 249

Query: 247 KHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYF 306
           ++ +T A I LR+ +QRGVVV+ KS+N +RI++N Q+F+F LT E+MK I+ L++N+ + 
Sbjct: 250 RYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFV 309

Query: 307 NSDSFASHPNYPYSDEY 323
               +  HP YP+ DEY
Sbjct: 310 ELLMWRDHPEYPFHDEY 326


>gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]
          Length = 316

 Score =  315 bits (806), Expect = 5e-86
 Identities = 151/314 (48%), Positives = 211/314 (67%), Gaps = 4/314 (1%)

Query: 10  LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
           LN+G  MP+LG GT+  P     +  E  K+AI+ G+RHID AH+Y NE +VG+AI+ K+
Sbjct: 7   LNNGAKMPILGLGTWKSPP---GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63

Query: 70  ADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELS 129
            +  VKRE++F  SKLW T+H   LV+ A + +L   +LDY+DLYLIH P   KPG+E  
Sbjct: 64  REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123

Query: 130 PTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 189
           P DE+G V+    ++  TW AME+  D GL K+IG+SNFN  Q+EMILNKPGLKYKP  N
Sbjct: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183

Query: 190 QVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHK 249
           Q+ECHPY  + KL+ +C+SK IV+ AYS LGS  D+ W  P  P LLEDP + A+A KH 
Sbjct: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP-DRPWAKPEDPSLLEDPRIKAIAAKHN 242

Query: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSD 309
           +T A + +R+ +QR +VV+ KS   +RI +N +VF+F+L+++DM  +   +RN       
Sbjct: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302

Query: 310 SFASHPNYPYSDEY 323
           S  SH +YP+ +E+
Sbjct: 303 SCTSHKDYPFHEEF 316


>gi|223468663 aldo-keto reductase family 1, member B10 [Homo
           sapiens]
          Length = 316

 Score =  298 bits (762), Expect = 6e-81
 Identities = 150/316 (47%), Positives = 204/316 (64%), Gaps = 4/316 (1%)

Query: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
           V+L+    MP++G GT+   + P  K  E  K+AI+AG+RHID A++Y NE +VG AI+ 
Sbjct: 5   VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61

Query: 68  KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
           KI + +VKRED+F  SKLW TF    LVR A E +LK  +L Y+D+YLIH P   K G++
Sbjct: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121

Query: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
           L P D+ G  I         WEAME+  D GL K++GVSNF+  Q+E +LNKPGLKYKPV
Sbjct: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181

Query: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKK 247
            NQVECHPY  + KL+ +C SK I + AYS LGS  D+ W  P  P LLEDP +  +A K
Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-DRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFN 307
           HK+T A + +R+ +QR V+V+ KS    RI +N+QVF+F+L+ E+M  I   +RN    N
Sbjct: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300

Query: 308 SDSFASHPNYPYSDEY 323
               +   +YP++ EY
Sbjct: 301 VLQSSHLEDYPFNAEY 316


>gi|122937516 aldo-keto reductase family 1, member B10-like [Homo
           sapiens]
          Length = 316

 Score =  286 bits (731), Expect = 2e-77
 Identities = 144/316 (45%), Positives = 198/316 (62%), Gaps = 4/316 (1%)

Query: 8   VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
           V+L+    MP++G GT+        K  E  K+AI+A +RHID A+ Y N+ +VG AI+ 
Sbjct: 5   VELSTKAKMPIVGLGTWRSL---LGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQE 61

Query: 68  KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE 127
           KI + +V RED+F  SK+W TF    LVR A E +LK  +L Y+D+YLIH P   K G++
Sbjct: 62  KIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDD 121

Query: 128 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
             P D+ G +I         WEAME+  D GL K++GVSNFN  Q+E +LNKPGLKYKPV
Sbjct: 122 FFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPV 181

Query: 188 CNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKK 247
            NQVECHPY  + KL+ +C SK I + AYS LGS  D+ W  P  P LLEDP +  +A K
Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSP-DRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFN 307
           HK+T A + +R+ +QR V V+ KS     I +N+QVF+F+L+ E+M  I   +RN   F+
Sbjct: 241 HKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD 300

Query: 308 SDSFASHPNYPYSDEY 323
              F+   ++P+  EY
Sbjct: 301 FKEFSHLEDFPFDAEY 316


>gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo
           sapiens]
          Length = 320

 Score =  264 bits (674), Expect = 9e-71
 Identities = 141/327 (43%), Positives = 196/327 (59%), Gaps = 29/327 (8%)

Query: 16  MPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 75
           +P +G  ++   +    K  E  K AI+AG+RH D A+ Y+NE +VG  IR KI +G+V+
Sbjct: 4   IPAVGLSSW---KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60

Query: 76  REDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGE--------E 127
           RED+F  +KLW T H+  LV  A   SLK  +L+Y+DLYLIH PM  KP          E
Sbjct: 61  REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120

Query: 128 LS-----------PTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMI 176
           LS           P DE+  VI    D   TWEAME     GL K+IGVSNFN  QLE +
Sbjct: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180

Query: 177 LNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLL 236
           LNKPGL++KP+ NQ+ECHPY  +  L+ FC+S+D+ + AY  LG   +   VD     L+
Sbjct: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE--GVD-----LI 233

Query: 237 EDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAI 296
           ++PV+  +AK+H ++PA I +R+Q+QR V+V+  S     I++N+QVF+F+LT  DM  I
Sbjct: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNI 293

Query: 297 DGLDRNLHYFNSDSFASHPNYPYSDEY 323
             L+RNL         +H +YP+  EY
Sbjct: 294 LSLNRNLRLAMFPITKNHKDYPFHIEY 320


>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  257 bits (656), Expect = 1e-68
 Identities = 135/327 (41%), Positives = 205/327 (62%), Gaps = 16/327 (4%)

Query: 7   CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
           CV L+ G  MP++G GT+   E  + KA    K A+  G+RHID A +Y NE ++G A++
Sbjct: 5   CVLLHTGQKMPLIGLGTWKS-EPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61

Query: 67  SKIADG-SVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
             +  G +V RE++F TSKLW+T H PE V PAL  +L   QL+Y+DLYL+H P + + G
Sbjct: 62  EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121

Query: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
           +   P + +G + +D      TW+A+E     GL +++G+SNFN RQ++ IL+   +  +
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179

Query: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALA 245
           P   QVECHPY  +++L+  C+++ + + AYS LGS  D+ W DP+ PVLLE+PV+ ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS-DRAWRDPDEPVLLEEPVVLALA 238

Query: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHY 305
           +K+ R+PA I LR+Q+QR V+ + KS    RI QN++VF+F  + E+MK ++ L++N  Y
Sbjct: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298

Query: 306 F---------NSDSFASHPNYPYSDEY 323
                          A HP YP++D Y
Sbjct: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325


>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  257 bits (656), Expect = 1e-68
 Identities = 135/327 (41%), Positives = 205/327 (62%), Gaps = 16/327 (4%)

Query: 7   CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
           CV L+ G  MP++G GT+   E  + KA    K A+  G+RHID A +Y NE ++G A++
Sbjct: 5   CVLLHTGQKMPLIGLGTWKS-EPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61

Query: 67  SKIADG-SVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
             +  G +V RE++F TSKLW+T H PE V PAL  +L   QL+Y+DLYL+H P + + G
Sbjct: 62  EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121

Query: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
           +   P + +G + +D      TW+A+E     GL +++G+SNFN RQ++ IL+   +  +
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179

Query: 186 PVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALA 245
           P   QVECHPY  +++L+  C+++ + + AYS LGS  D+ W DP+ PVLLE+PV+ ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSS-DRAWRDPDEPVLLEEPVVLALA 238

Query: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHY 305
           +K+ R+PA I LR+Q+QR V+ + KS    RI QN++VF+F  + E+MK ++ L++N  Y
Sbjct: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298

Query: 306 F---------NSDSFASHPNYPYSDEY 323
                          A HP YP++D Y
Sbjct: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325


>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
          Length = 139

 Score =  222 bits (566), Expect = 3e-58
 Identities = 108/123 (87%), Positives = 113/123 (91%)

Query: 1   MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60
           MDSK+QCVKLNDGHFMPVLGFGTYAP EVP+SKALE  KLAIEAGF HIDSAH+YNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
           VGLAIRSKIADGSVKREDIFYTSKLWS  HRPELVRPALE SLK  QLDYVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SLK 123
           S+K
Sbjct: 121 SVK 123


>gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo
           sapiens]
          Length = 249

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/146 (32%), Positives = 66/146 (45%), Gaps = 17/146 (11%)

Query: 28  EVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A  VT+  +E G   ID+A LY++ +      GL +R   +D  VK   I   +
Sbjct: 24  DAPTSAA--VTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78

Query: 84  KLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE----LSPTDENGKVI 138
             W     +P+ VR  LE SLK+ Q   VDL+ +H+P    P EE         + GK +
Sbjct: 79  NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138

Query: 139 FDIVDLCTTWEAMEKCKDAGLAKSIG 164
              +     WE  E C    L KS G
Sbjct: 139 ELGLSNYAAWEVAEICT---LCKSNG 161


>gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo
           sapiens]
          Length = 331

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/146 (32%), Positives = 66/146 (45%), Gaps = 17/146 (11%)

Query: 28  EVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A  VT+  +E G   ID+A LY++ +      GL +R   +D  VK   I   +
Sbjct: 24  DAPTSAA--VTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78

Query: 84  KLW-STFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE----LSPTDENGKVI 138
             W     +P+ VR  LE SLK+ Q   VDL+ +H+P    P EE         + GK +
Sbjct: 79  NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138

Query: 139 FDIVDLCTTWEAMEKCKDAGLAKSIG 164
              +     WE  E C    L KS G
Sbjct: 139 ELGLSNYAAWEVAEICT---LCKSNG 161


>gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]
          Length = 331

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 15/145 (10%)

Query: 28  EVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A  VT+  +E G   ID+A +Y+  +      GL +R   +D  VK +      
Sbjct: 24  DAPTSAA--VTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79

Query: 84  KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE----LSPTDENGKVIF 139
            L+    +P+ +R  LE SLK+ Q   VDL+ +H P    P EE         + GK + 
Sbjct: 80  PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139

Query: 140 DIVDLCTTWEAMEKCKDAGLAKSIG 164
             +     WE  E C    L KS G
Sbjct: 140 LGLSNYAAWEVAEICT---LCKSNG 161


>gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]
          Length = 359

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 42/146 (28%), Positives = 63/146 (43%), Gaps = 17/146 (11%)

Query: 28  EVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A    +  +E G   +D+A +Y++ +      GL +     D  VK   I   +
Sbjct: 52  DAPASAA--AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKA 106

Query: 84  KLWSTFH-RPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE----LSPTDENGKVI 138
             W     +P+ VR  LE SLK+ Q   VDL+ +H+P    P EE         + GK +
Sbjct: 107 NPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFV 166

Query: 139 FDIVDLCTTWEAMEKCKDAGLAKSIG 164
              +    +WE  E C    L KS G
Sbjct: 167 ELGLSNYASWEVAEICT---LCKSNG 189


>gi|27436964 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 3 [Homo sapiens]
          Length = 401

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 44/201 (21%)

Query: 19  LGFGTYAP--PEVPRSKALEVTKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A  +  +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 86  LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 141

Query: 74  VKREDIFYTSKLW--------STFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
            +R  +  T+KL+            R  ++   L+ SL++ QL+YVD+   + P S  P 
Sbjct: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIE-GLKGSLQRLQLEYVDVVFANRPDSNTPM 200

Query: 126 EE----LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
           EE    ++     G  ++      + W AME  +   +A          RQ  MI     
Sbjct: 201 EEIVRAMTHVINQGMAMYWGT---SRWSAMEIMEAYSVA----------RQFNMI----- 242

Query: 182 LKYKPVCNQVECHPYFNRSKL 202
               PVC Q E H  F R K+
Sbjct: 243 ---PPVCEQAEYH-LFQREKV 259


>gi|27436962 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 2 [Homo sapiens]
          Length = 408

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 44/201 (21%)

Query: 19  LGFGTYAP--PEVPRSKALEVTKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A  +  +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 93  LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 148

Query: 74  VKREDIFYTSKLW--------STFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
            +R  +  T+KL+            R  ++   L+ SL++ QL+YVD+   + P S  P 
Sbjct: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIE-GLKGSLQRLQLEYVDVVFANRPDSNTPM 207

Query: 126 EE----LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
           EE    ++     G  ++      + W AME  +   +A          RQ  MI     
Sbjct: 208 EEIVRAMTHVINQGMAMYWGT---SRWSAMEIMEAYSVA----------RQFNMI----- 249

Query: 182 LKYKPVCNQVECHPYFNRSKL 202
               PVC Q E H  F R K+
Sbjct: 250 ---PPVCEQAEYH-LFQREKV 266


>gi|27436966 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 1 [Homo sapiens]
          Length = 419

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 44/201 (21%)

Query: 19  LGFGTYAP--PEVPRSKALEVTKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A  +  +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 159

Query: 74  VKREDIFYTSKLW--------STFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
            +R  +  T+KL+            R  ++   L+ SL++ QL+YVD+   + P S  P 
Sbjct: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIE-GLKGSLQRLQLEYVDVVFANRPDSNTPM 218

Query: 126 EE----LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
           EE    ++     G  ++      + W AME  +   +A          RQ  MI     
Sbjct: 219 EEIVRAMTHVINQGMAMYWGT---SRWSAMEIMEAYSVA----------RQFNMI----- 260

Query: 182 LKYKPVCNQVECHPYFNRSKL 202
               PVC Q E H  F R K+
Sbjct: 261 ---PPVCEQAEYH-LFQREKV 277


>gi|4504825 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 1 [Homo sapiens]
          Length = 367

 Score = 33.9 bits (76), Expect = 0.20
 Identities = 48/199 (24%), Positives = 79/199 (39%), Gaps = 40/199 (20%)

Query: 19  LGFGTYAP--PEVPRSKALEVTKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A ++  LA + G    D+A +Y     E  +G  I+ K     
Sbjct: 52  LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----G 107

Query: 74  VKREDIFYTSKL-WSTFHRPEL------VRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
            +R  +  T+K+ W      E       +   L+ SL++ QL+YVD+   + P    P E
Sbjct: 108 WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPME 167

Query: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK- 185
           E                   T  AM    + G+A   G S ++  ++ M       ++  
Sbjct: 168 E-------------------TVRAMTHVINQGMAMYWGTSRWSSMEI-MEAYSVARQFNL 207

Query: 186 --PVCNQVECHPYFNRSKL 202
             P+C Q E H  F R K+
Sbjct: 208 TPPICEQAEYH-MFQREKV 225


>gi|27436969 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 2 [Homo sapiens]
          Length = 353

 Score = 33.9 bits (76), Expect = 0.20
 Identities = 48/199 (24%), Positives = 79/199 (39%), Gaps = 40/199 (20%)

Query: 19  LGFGTYAP--PEVPRSKALEVTKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A ++  LA + G    D+A +Y     E  +G  I+ K     
Sbjct: 38  LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----G 93

Query: 74  VKREDIFYTSKL-WSTFHRPEL------VRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
            +R  +  T+K+ W      E       +   L+ SL++ QL+YVD+   + P    P E
Sbjct: 94  WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPME 153

Query: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK- 185
           E                   T  AM    + G+A   G S ++  ++ M       ++  
Sbjct: 154 E-------------------TVRAMTHVINQGMAMYWGTSRWSSMEI-MEAYSVARQFNL 193

Query: 186 --PVCNQVECHPYFNRSKL 202
             P+C Q E H  F R K+
Sbjct: 194 TPPICEQAEYH-MFQREKV 211


>gi|27436971 potassium voltage-gated channel, shaker-related
           subfamily, beta member 3 [Homo sapiens]
          Length = 404

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 48/198 (24%), Positives = 74/198 (37%), Gaps = 38/198 (19%)

Query: 19  LGFGTYAP--PEVPRSKALEVTKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A +V  +A E G    D+A +Y     E  +G  ++SK     
Sbjct: 93  LGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK----G 148

Query: 74  VKREDIFYTSKL-WSTFHRPEL------VRPALENSLKKAQLDYVDLYLIHSPMSLKPGE 126
            +R     T+K+ W      E       +   L  SL++ QL YVD+   +      P E
Sbjct: 149 WRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPME 208

Query: 127 ELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL--EMILNKPGLKY 184
           E+                     AM    + GLA   G S +   ++     + +     
Sbjct: 209 EIV-------------------RAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLI 249

Query: 185 KPVCNQVECHPYFNRSKL 202
            PVC Q E H  F R K+
Sbjct: 250 PPVCEQAE-HHLFQREKV 266


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 1/96 (1%)

Query: 66  RSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125
           R+ +   SV+ ED F+  +++S     EL+ P  E   +   +  +DL L+ + +  KP 
Sbjct: 673 RTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLL-TRIPGKPY 731

Query: 126 EELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAK 161
           +E  P     K + +        +A EK  + G  K
Sbjct: 732 KETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRK 767


>gi|154354966 inner membrane protein, mitochondrial isoform 3 [Homo
           sapiens]
          Length = 747

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 16/45 (35%), Positives = 20/45 (44%)

Query: 101 NSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLC 145
           NSL +  L Y+   L+  P  LKP  EL P D N   +      C
Sbjct: 642 NSLYQYFLSYLQSLLLFPPQQLKPPPELCPEDINTFKLLSYASYC 686


>gi|154354962 inner membrane protein, mitochondrial isoform 2 [Homo
           sapiens]
          Length = 757

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 16/45 (35%), Positives = 20/45 (44%)

Query: 101 NSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLC 145
           NSL +  L Y+   L+  P  LKP  EL P D N   +      C
Sbjct: 652 NSLYQYFLSYLQSLLLFPPQQLKPPPELCPEDINTFKLLSYASYC 696


>gi|154354964 inner membrane protein, mitochondrial isoform 1 [Homo
           sapiens]
          Length = 758

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 16/45 (35%), Positives = 20/45 (44%)

Query: 101 NSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLC 145
           NSL +  L Y+   L+  P  LKP  EL P D N   +      C
Sbjct: 653 NSLYQYFLSYLQSLLLFPPQQLKPPPELCPEDINTFKLLSYASYC 697


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,626,003
Number of Sequences: 37866
Number of extensions: 535844
Number of successful extensions: 1067
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1021
Number of HSP's gapped (non-prelim): 27
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.