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Search of human proteins with 24430215
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24430215 interleukin 10 receptor, beta precursor [Homo
sapiens]
(325 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens] 692 0.0
gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens] 95 1e-19
gi|31083156 interleukin 20 receptor, alpha [Homo sapiens] 91 1e-18
gi|47419934 interferon gamma receptor 2 precursor [Homo sapiens] 90 3e-18
gi|40255073 interleukin 20 receptor beta precursor [Homo sapiens] 70 3e-12
gi|31317241 interleukin 22-binding protein isoform 2 [Homo sapiens] 61 1e-09
gi|4557880 interferon gamma receptor 1 precursor [Homo sapiens] 49 6e-06
gi|16418459 interleukin 22-binding protein isoform 1 [Homo sapiens] 48 1e-05
gi|4559408 colony stimulating factor 2 receptor, beta precursor ... 44 1e-04
gi|222136575 interleukin 10 receptor, alpha precursor [Homo sapi... 42 6e-04
gi|31317243 interleukin 22-binding protein isoform 3 [Homo sapiens] 41 0.001
gi|25014103 interleukin 28 receptor, alpha isoform 1 [Homo sapiens] 41 0.002
gi|28416909 interleukin 28 receptor, alpha isoform 2 [Homo sapiens] 39 0.005
gi|4503641 coagulation factor III precursor [Homo sapiens] 39 0.006
gi|222537743 protein tyrosine phosphatase, receptor type, Q [Hom... 39 0.006
gi|28416911 interleukin 28 receptor, alpha isoform 3 [Homo sapiens] 37 0.031
gi|21450717 sushi domain containing 3 [Homo sapiens] 35 0.12
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 34 0.20
gi|4557040 oncostatin M receptor [Homo sapiens] 32 0.59
gi|31083174 interleukin 21 receptor precursor [Homo sapiens] 32 1.0
gi|11141869 interleukin 21 receptor precursor [Homo sapiens] 32 1.0
gi|31083180 interleukin 21 receptor precursor [Homo sapiens] 32 1.0
gi|222352127 sidekick 2 [Homo sapiens] 31 1.7
gi|119395738 insulin receptor isoform Short precursor [Homo sapi... 30 2.2
gi|119395736 insulin receptor isoform Long precursor [Homo sapiens] 30 2.2
gi|31317239 interleukin 22 receptor, alpha 1 [Homo sapiens] 30 2.9
gi|19924165 proto-oncogene c-ros-1 protein precursor [Homo sapiens] 30 2.9
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 30 2.9
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 30 2.9
gi|4507103 small nuclear RNA activating complex, polypeptide 2, ... 30 2.9
>gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens]
Length = 325
Score = 692 bits (1787), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR 60
MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR
Sbjct: 1 MAWSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR 60
Query: 61 IFQDKCMNTTLTECDFSSLSKYGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQV 120
IFQDKCMNTTLTECDFSSLSKYGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQV
Sbjct: 61 IFQDKCMNTTLTECDFSSLSKYGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQV 120
Query: 121 EVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRN 180
EVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRN
Sbjct: 121 EVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRN 180
Query: 181 LEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLG 240
LEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLG
Sbjct: 181 LEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLG 240
Query: 241 CFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAE 300
CFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAE
Sbjct: 241 CFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFSFPLSDENDVFDKLSVIAE 300
Query: 301 DSESGKQNPGDSCSLGTPPGQGPQS 325
DSESGKQNPGDSCSLGTPPGQGPQS
Sbjct: 301 DSESGKQNPGDSCSLGTPPGQGPQS 325
>gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens]
Length = 557
Score = 94.7 bits (234), Expect = 1e-19
Identities = 79/322 (24%), Positives = 145/322 (45%), Gaps = 28/322 (8%)
Query: 2 AWSLGSWLG-GCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR 60
+W +G + C+ + +PPPEN+ ++ N +L+W+ + N+TF Q+L
Sbjct: 209 SWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWD---YTYANMTFQVQWLHAF 265
Query: 61 IFQDK------------CMNTTLTECDF-SSLSKYGDHTLRVRAEFADEHSDWVN-ITFC 106
+ ++ C N T+C F ++ + G + LRV+A + S W I F
Sbjct: 266 LKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFD 325
Query: 107 PVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEK 166
+ PP + L+DS H+ APK T +++ Y + +W+N ++ +
Sbjct: 326 TEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGN--TPVIQDY--PLIYEIIFWENTSNAE 381
Query: 167 FQITPQYDFEVLRNLEPWTTYCVQVRGFLPDR--NKAGEWSEPVCEQTTHDETVPSWMVA 224
+I + + NL+P T YCV+ R D NK+ +S+ VCE+T T W++
Sbjct: 382 RKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLIV 441
Query: 225 VILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFSFP 284
I +A +F + + L C+ + P +S+ ++ E P N LL S
Sbjct: 442 GICIA-LFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDEYFSE---QPLKNLLLSTSEE 497
Query: 285 LSDENDVFDKLSVIAEDSESGK 306
++ + + +S IA E+ +
Sbjct: 498 QIEKCFIIENISTIATVEETNQ 519
Score = 85.9 bits (211), Expect = 4e-17
Identities = 67/224 (29%), Positives = 109/224 (48%), Gaps = 19/224 (8%)
Query: 3 WSLGSWLGGCLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQY----LS 58
W L + GG L S P+ V ++ ++ IL+W + GN+TF+ Y +
Sbjct: 19 WVLSAAAGGKNLKS-------PQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMD 71
Query: 59 YRIFQDKCMNTTLTECDFSSL--SKYGDHTLRVRAEFADEHSDWVNI-TFCPVDDTIIGP 115
I C N T T+C+FSSL + Y + LR+RAE + S W + +F P IGP
Sbjct: 72 NWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAE-KENTSSWYEVDSFTPFRKAQIGP 130
Query: 116 PGMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDF 175
P + +E D + ++P ++ W + + S+TY++ WKN + + +I Y
Sbjct: 131 PEVHLEA-EDKAIVIHISPGTKDSV-MWALDGL--SFTYSLVIWKNSSGVEERIENIYSR 186
Query: 176 EVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVP 219
+ L P TTYC++V+ L K G +S C +TT + +P
Sbjct: 187 HKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELP 230
>gi|31083156 interleukin 20 receptor, alpha [Homo sapiens]
Length = 553
Score = 90.9 bits (224), Expect = 1e-18
Identities = 84/322 (26%), Positives = 142/322 (44%), Gaps = 27/322 (8%)
Query: 19 GMVPPPENVRMNSVNFKNILQWESPAFAKG-NLTFTAQYLSYR----IFQDKCMNTTLTE 73
G +P P N+ S+N KN+LQW P +G +T+T QY Y + + +C N T
Sbjct: 35 GGLPKPANITFLSINMKNVLQWTPPEGLQGVKVTYTVQYFIYGQKKWLNKSECRNINRTY 94
Query: 74 CDFSSLSKYGDHTL--RVRAEFADEHSDWVNI-TFCPVDDTIIGPPGMQVEVLADSLHMR 130
CD S+ + +H +V+A + + S W F P +T IGPP + + S+ +
Sbjct: 95 CDLSAETSDYEHQYYAKVKAIWGTKCSKWAESGRFYPFLETQIGPPEVALTTDEKSISVV 154
Query: 131 FLAP---KIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTY 187
AP K E +M+ +Y++ YNV ++ + VL LEP T Y
Sbjct: 155 LTAPEKWKRNPEDLPVSMQQIYSNLKYNVSVLNTKSNRTWSQCVTNHTLVLTWLEPNTLY 214
Query: 188 CVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLGCFALLWC 247
CV V F+P + + SE C +T D++ S A I+ V V + + + +
Sbjct: 215 CVHVESFVPGPPRRAQPSEKQCARTLKDQS--SEFKAKIIFWYVLPVSITVFLFSVMGYS 272
Query: 248 VYKKTKYAFSPRNSLPQHL---------KEFLGHPHHNTLLFFSFPLSDENDV-FDKLSV 297
+Y +Y + P +L K F + F + +SD++ + +S+
Sbjct: 273 IY---RYIHVGKEKHPANLILIYGNEFDKRFFVPAEKIVINFITLNISDDSKISHQDMSL 329
Query: 298 IAEDSE-SGKQNPGDSCSLGTP 318
+ + S+ S +P S +L P
Sbjct: 330 LGKSSDVSSLNDPQPSGNLRPP 351
>gi|47419934 interferon gamma receptor 2 precursor [Homo sapiens]
Length = 337
Score = 89.7 bits (221), Expect = 3e-18
Identities = 85/330 (25%), Positives = 141/330 (42%), Gaps = 41/330 (12%)
Query: 1 MAWSLGSWLGGCLLVSA-----LGMVPPPENVRMNSVNFKNILQWESPAFAKGNLT---- 51
+ WSL LG +A L +P P++ ++ N + +L WE A +
Sbjct: 5 LLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRPVVYQ 64
Query: 52 ----------FTAQYLSYRIFQDKCMNTTLTECDFSSLSKYGDH------TLRVRAEFAD 95
FTA +S + C T TECDF++ S TLR+RAE
Sbjct: 65 VQFKYTDSKWFTADIMSIGV---NCTQITATECDFTAASPSAGFPMDFNVTLRLRAELGA 121
Query: 96 EHSDWVNIT-FCPVDDTIIGPP-GMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWT 153
HS WV + F + +GPP ++V SL +RF +P ++ + +
Sbjct: 122 LHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSP-----FDIADTSTAF--FC 174
Query: 154 YNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFL----PDRNKAGEWSEPVC 209
Y V YW+ G ++ + + + L NL+P YC+QV+ L + + G S C
Sbjct: 175 YYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISC 234
Query: 210 EQTTHDETVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKEF 269
+T D + V +I + + ++ + CF L+ KY F S+P ++E+
Sbjct: 235 YETMADASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEY 294
Query: 270 LGHPHHNTLLFFSFPLSDENDVFDKLSVIA 299
L P L S ++DV+D +S+I+
Sbjct: 295 LKDPTQPILEALDKDSSPKDDVWDSVSIIS 324
>gi|40255073 interleukin 20 receptor beta precursor [Homo sapiens]
Length = 311
Score = 69.7 bits (169), Expect = 3e-12
Identities = 70/272 (25%), Positives = 119/272 (43%), Gaps = 37/272 (13%)
Query: 12 CLLVSALGMVPPPENVRMNSVNFKNILQWESPAFAKG-----NLTFTAQYLSYR-----I 61
CLL + ++P P+N+ + S N K++L W SP A G ++ + +Y S I
Sbjct: 26 CLLTDEVAILPAPQNLSVLSTNMKHLLMW-SPVIAPGETVYYSVEYQGEYESLYTSHIWI 84
Query: 62 FQDKCMNTTLTECDFS-SLSKYGDHTLRVRAEFADEHSDWVNITFCPV--DDTIIGPPGM 118
C T ECD + ++ + LRVRA + S W +I P + TI+ PGM
Sbjct: 85 PSSWCSLTEGPECDVTDDITATVPYNLRVRATLGSQTSAW-SILKHPFNRNSTILTRPGM 143
Query: 119 QVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKN--GTDEKFQITPQYDFE 176
E+ D H+ + ++E + V YW+ G +E ++
Sbjct: 144 --EITKDGFHLVIELEDLGPQFE------------FLVAYWRREPGAEEHVKMVRSGGIP 189
Query: 177 V-LRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVC 235
V L +EP YCV+ + F+ + +S+ C + E +P +V + FM+
Sbjct: 190 VHLETMEPGAAYCVKAQTFVKAIGRYSAFSQTECVE-VQGEAIP--LVLALFAFVGFMLI 246
Query: 236 LALLGCFALLWCVYKKTKYAFSPRNSLPQHLK 267
L ++ F +W + + +Y+ P LP LK
Sbjct: 247 LVVVPLF--VWKMGRLLQYSCCPVVVLPDTLK 276
>gi|31317241 interleukin 22-binding protein isoform 2 [Homo sapiens]
Length = 231
Score = 61.2 bits (147), Expect = 1e-09
Identities = 57/205 (27%), Positives = 90/205 (43%), Gaps = 27/205 (13%)
Query: 24 PENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIF-------QDKCMNTTLTECDF 76
P+ V+ S NF NILQW+ GN + ++ Y+I+ ++ C T CD
Sbjct: 31 PQRVQFQSRNFHNILQWQPGRALTGN--SSVYFVQYKIYGQRQWKNKEDCWGTQELSCDL 88
Query: 77 SSLSK------YGDHTLRVRAEFADEHSDW-VNITFCPVDDTIIGPPGMQVEVLADSLHM 129
+S + YG RVRA A +S+W + F P +T I PP M + + SL +
Sbjct: 89 TSETSDIQEPYYG----RVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLV 144
Query: 130 RFLAPKIENEYETWTMKNV----YNSWTYNVQYWKNGTDEKFQITPQYDFEV-LRNLEPW 184
AP + Y+ KNV Y Y V N +++ ++ V + L P
Sbjct: 145 ILHAPNLPYRYQ--KEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPH 202
Query: 185 TTYCVQVRGFLPDRNKAGEWSEPVC 209
++YCV + P ++ + SE C
Sbjct: 203 SSYCVVAEIYQPMLDRRSQRSEERC 227
>gi|4557880 interferon gamma receptor 1 precursor [Homo sapiens]
Length = 489
Score = 48.9 bits (115), Expect = 6e-06
Identities = 58/246 (23%), Positives = 98/246 (39%), Gaps = 30/246 (12%)
Query: 21 VPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRI----FQDKCMNTTLTECDF 76
VP P NV + S N I+ WE + + FT + +Y + + D C+N + C+
Sbjct: 29 VPTPTNVTIESYNMNPIVYWEYQIMPQVPV-FTVEVKNYGVKNSEWIDACINISHHYCNI 87
Query: 77 SSLSKYGDHT----LRVRAEFADEHSDWV-NITFCPVDDTIIGPPGMQV-----EVLADS 126
S GD + +RV+A + S + + F D IGPP + + +++ D
Sbjct: 88 S--DHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVCRDGKIGPPKLDIRKEEKQIMIDI 145
Query: 127 LHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEV--------- 177
H E E + Y YNV NG++ +++I Q + +
Sbjct: 146 FHPSVFVNGDEQEVDYDPETTCYIR-VYNVYVRMNGSEIQYKILTQKEDDCDEIQCQLAI 204
Query: 178 -LRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCL 236
+ +L + YCV G L E S+ VC + S + V+ +F+V
Sbjct: 205 PVSSLN--SQYCVSAEGVLHVWGVTTEKSKEVCITIFNSSIKGSLWIPVVAALLLFLVLS 262
Query: 237 ALLGCF 242
+ CF
Sbjct: 263 LVFICF 268
>gi|16418459 interleukin 22-binding protein isoform 1 [Homo sapiens]
Length = 263
Score = 47.8 bits (112), Expect = 1e-05
Identities = 57/237 (24%), Positives = 89/237 (37%), Gaps = 59/237 (24%)
Query: 24 PENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIF--------------------- 62
P+ V+ S NF NILQW+ GN + ++ Y+I
Sbjct: 31 PQRVQFQSRNFHNILQWQPGRALTGN--SSVYFVQYKIMFSCSMKSSHQKPSGCWQHISC 88
Query: 63 ------------------QDKCMNTTLTECDFSSLSK------YGDHTLRVRAEFADEHS 98
++ C T CD +S + YG RVRA A +S
Sbjct: 89 NFPGCRTLAKYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYG----RVRAASAGSYS 144
Query: 99 DW-VNITFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNV----YNSWT 153
+W + F P +T I PP M + + SL + AP + Y+ KNV Y
Sbjct: 145 EWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRYQ--KEKNVSIEDYYELL 202
Query: 154 YNVQYWKNGTDEKFQITPQYDFEV-LRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVC 209
Y V N +++ ++ V + L P ++YCV + P ++ + SE C
Sbjct: 203 YRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQPMLDRRSQRSEERC 259
>gi|4559408 colony stimulating factor 2 receptor, beta precursor
[Homo sapiens]
Length = 897
Score = 44.3 bits (103), Expect = 1e-04
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 22/165 (13%)
Query: 82 YGDHTLRVRAEFADEH-SDWVNITFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEY 140
+G + + V+ A++H VNI + PP + V DS +R +
Sbjct: 316 HGQYIVSVQPRRAEKHIKSSVNIQ--------MAPPSLNVTKDGDSYSLR---------W 358
Query: 141 ETWTMKNVYNSWTYNVQYWKNGT---DEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPD 197
ET M+ + T+ +QY K+ D K + L LEP T Y +VR
Sbjct: 359 ETMKMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVRTSR 418
Query: 198 RNKAGEWSEPVCEQTTHDETV-PSWMVAVILMASVFMVCLALLGC 241
G WSE ++ E+V P W++A+I++ V LAL C
Sbjct: 419 TGYNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFC 463
>gi|222136575 interleukin 10 receptor, alpha precursor [Homo
sapiens]
Length = 578
Score = 42.4 bits (98), Expect = 6e-04
Identities = 56/244 (22%), Positives = 98/244 (40%), Gaps = 15/244 (6%)
Query: 21 VPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIFQ----DKCMNTTLTECDF 76
+P P +V + F +IL W + + L Y I C T +
Sbjct: 26 LPSPPSVWFEAEFFHHILHWTPIPNQSESTCYEVALLRYGIESWNSISNCSQTLSYDLTA 85
Query: 77 SSLSKY--GDHTLRVRAEFADEHSDW-VNITFCPVDDTIIGPPGMQVEVLADSLHMRFLA 133
+L Y + RVRA HS+W V T VD+ + + +E+ + +
Sbjct: 86 VTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSVDEVTLTVGSVNLEIHNGFILGKIQL 145
Query: 134 PKIENEYETWTMKNVYNSWT-YNVQYWKNGTDEKF--QITPQYDFEVLRNLEPWTTYCVQ 190
P+ + T +++++ + Y + K + F + +F +L + E +CVQ
Sbjct: 146 PRPKMAPANDTYESIFSHFREYEIAIRKVPGNFTFTHKKVKHENFSLLTSGEVGE-FCVQ 204
Query: 191 VRGFLPDRNKAGEWSEPVCEQTTHDE-TVPSWMVAVILMASVFMVCLALLGCFALLWCVY 249
V+ + R+ G WS+ C T TV + +I A V ++ AL C AL V
Sbjct: 205 VKPSVASRSNKGMWSKEECISLTRQYFTVTN---VIIFFAFVLLLSGALAYCLALQLYVR 261
Query: 250 KKTK 253
++ K
Sbjct: 262 RRKK 265
>gi|31317243 interleukin 22-binding protein isoform 3 [Homo sapiens]
Length = 130
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 19/90 (21%)
Query: 24 PENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIF-------QDKCMNTTLTECDF 76
P+ V+ S NF NILQW+ GN + ++ Y+I+ ++ C T CD
Sbjct: 31 PQRVQFQSRNFHNILQWQPGRALTGN--SSVYFVQYKIYGQRQWKNKEDCWGTQELSCDL 88
Query: 77 SSLSK------YGDHTLRVRAEFADEHSDW 100
+S + YG RVRA A +S+W
Sbjct: 89 TSETSDIQEPYYG----RVRAASAGSYSEW 114
>gi|25014103 interleukin 28 receptor, alpha isoform 1 [Homo sapiens]
Length = 520
Score = 40.8 bits (94), Expect = 0.002
Identities = 73/298 (24%), Positives = 116/298 (38%), Gaps = 36/298 (12%)
Query: 12 CLLVSALGM--VPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIFQ-----D 64
CLL +A G + PP+NV + S NF L W ++T+ Y S + +
Sbjct: 13 CLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRRRWREVE 72
Query: 65 KCMNTTLTECDFSSLSK---YGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQVE 121
+C T C L K Y RVR S WV + +D P V
Sbjct: 73 ECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEY--LDYLFEVEPAPPVL 130
Query: 122 VLADSLHMRFLAPKIENEYETWTMKNVYN--SWTYNVQYWKNGTDEK--FQITPQYDFEV 177
VL + +I + T+ + Y V +WK G K F +TP + V
Sbjct: 131 VLTQT-------EEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTP-HGQPV 182
Query: 178 LRNLEPWTT--YCVQVRG-FLPDRNKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMV 234
L+P + +C+ R + K ++S+P C VP A +++ S+ ++
Sbjct: 183 QITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLL----EVPEANWAFLVLPSL-LI 237
Query: 235 CLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKEFLGHPHHNTLLFFSFPLSDENDVF 292
L ++ ++W + R +P+ L +F GH H S P S ND+F
Sbjct: 238 LLLVIAAGGVIWKTLMGNPW--FQRAKMPRAL-DFSGHTHPVATFQPSRPES-VNDLF 291
>gi|28416909 interleukin 28 receptor, alpha isoform 2 [Homo sapiens]
Length = 491
Score = 39.3 bits (90), Expect = 0.005
Identities = 60/252 (23%), Positives = 99/252 (39%), Gaps = 33/252 (13%)
Query: 12 CLLVSALGM--VPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIFQ-----D 64
CLL +A G + PP+NV + S NF L W ++T+ Y S + +
Sbjct: 13 CLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRRRWREVE 72
Query: 65 KCMNTTLTECDFSSLSK---YGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQVE 121
+C T C L K Y RVR S WV + +D P V
Sbjct: 73 ECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEY--LDYLFEVEPAPPVL 130
Query: 122 VLADSLHMRFLAPKIENEYETWTMKNVYN--SWTYNVQYWKNGTDEK--FQITPQYDFEV 177
VL + +I + T+ + Y V +WK G K F +TP + V
Sbjct: 131 VLTQT-------EEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTP-HGQPV 182
Query: 178 LRNLEPWTT--YCVQVRG-FLPDRNKAGEWSEPVC------EQTTHDETVPSWMVAVILM 228
L+P + +C+ R + K ++S+P C E +PS ++ ++++
Sbjct: 183 QITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAFLVLPSLLILLLVI 242
Query: 229 ASVFMVCLALLG 240
A+ ++ L+G
Sbjct: 243 AAGGVIWKTLMG 254
>gi|4503641 coagulation factor III precursor [Homo sapiens]
Length = 295
Score = 38.9 bits (89), Expect = 0.006
Identities = 56/239 (23%), Positives = 93/239 (38%), Gaps = 35/239 (14%)
Query: 26 NVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR-IFQDKCMNTTLTECDFS-SLSKYG 83
N+ S NFK IL+WE N +T Q + ++ KC TT TECD + + K
Sbjct: 43 NLTWKSTNFKTILEWEPKPV---NQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDV 99
Query: 84 DHTLRVR-----------AEFADEHSDWVNITFCPVDDTIIGPPGMQ-VEVLADSLHMRF 131
T R A E + F P +T +G P +Q E + +++
Sbjct: 100 KQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNV-- 157
Query: 132 LAPKIENEYETWTMKNVYNS--------WTYNVQYWKNGTDEKFQITPQYDFEVLRNLEP 183
+E+E N + S Y + YWK+ + K + E L +++
Sbjct: 158 ---TVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSGK-KTAKTNTNEFLIDVDK 213
Query: 184 WTTYCVQVRGFLPDR--NKAGEWSEPVCEQTTHDETVPSWMV--AVILMASVFMVCLAL 238
YC V+ +P R N+ S C E + + AV+ + + ++ LA+
Sbjct: 214 GENYCFSVQAVIPSRTVNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAI 272
>gi|222537743 protein tyrosine phosphatase, receptor type, Q [Homo
sapiens]
Length = 2299
Score = 38.9 bits (89), Expect = 0.006
Identities = 45/191 (23%), Positives = 82/191 (42%), Gaps = 42/191 (21%)
Query: 24 PENVRMNSVNFKNI------LQWESPAFAKGNLTFTAQYLSYRIFQDKCMNTTLTECDF- 76
P ++++ +N+KNI L W+ P + G +T Y + + ++ T + F
Sbjct: 569 PSSIKI--INYKNISSSSILLYWDPPEYPNGKITHYTIY-AMELDTNRAFQITTIDNSFL 625
Query: 77 -SSLSKYGDHTLRVRAE-------FADEHSDWVNITFCPVDDTIIGPPGMQV-EVLADSL 127
+ L KY + +RV A ++E+ +V + D+ P ++V +V AD +
Sbjct: 626 ITGLKKYTKYKMRVAASTHVGESSLSEENDIFVRTS---EDEPESSPQDVEVIDVTADEI 682
Query: 128 HMRFLAPKIEN----EYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFEVLRNLEP 183
+++ P+ N YE KN+ + Y KN + +LRNL P
Sbjct: 683 RLKWSPPEKPNGIIIAYEV-LYKNI------DTLYMKNTSTTDI---------ILRNLRP 726
Query: 184 WTTYCVQVRGF 194
T Y + VR +
Sbjct: 727 HTLYNISVRSY 737
Score = 28.5 bits (62), Expect = 8.5
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 8/67 (11%)
Query: 154 YNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTT 213
Y V +N T +++PQ L T+Y +VR AGE E C +T
Sbjct: 1373 YMVTVERNST----KVSPQDHMYTFIKLLANTSYVFKVRA----STSAGEGDESTCHVST 1424
Query: 214 HDETVPS 220
ETVPS
Sbjct: 1425 LPETVPS 1431
>gi|28416911 interleukin 28 receptor, alpha isoform 3 [Homo sapiens]
Length = 244
Score = 36.6 bits (83), Expect = 0.031
Identities = 54/215 (25%), Positives = 82/215 (38%), Gaps = 27/215 (12%)
Query: 12 CLLVSALGM--VPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIFQ-----D 64
CLL +A G + PP+NV + S NF L W ++T+ Y S + +
Sbjct: 13 CLLQAAPGRPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRRRWREVE 72
Query: 65 KCMNTTLTECDFSSLSK---YGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQVE 121
+C T C L K Y RVR S WV + +D P V
Sbjct: 73 ECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEY--LDYLFEVEPAPPVL 130
Query: 122 VLADSLHMRFLAPKIENEYETWTMKNVYN--SWTYNVQYWKNGTDEK--FQITPQYDFEV 177
VL + +I + T+ + Y V +WK G K F +TP + V
Sbjct: 131 VLTQT-------EEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTP-HGQPV 182
Query: 178 LRNLEPWTT--YCVQVRG-FLPDRNKAGEWSEPVC 209
L+P + +C+ R + K ++S+P C
Sbjct: 183 QITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTC 217
>gi|21450717 sushi domain containing 3 [Homo sapiens]
Length = 255
Score = 34.7 bits (78), Expect = 0.12
Identities = 45/187 (24%), Positives = 72/187 (38%), Gaps = 33/187 (17%)
Query: 160 KNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVR----------GFLPD--RNKAGEWS-- 205
+ GT K ++ PQ F+VLR + R G L + EWS
Sbjct: 28 RTGTCAKLRLPPQATFQVLRGNGASVGTVLMFRCPSNHQMVGSGLLTCTWKGSIAEWSSG 87
Query: 206 EPVCEQTTHDETV---PSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSL 262
PVC+ ET + + +++ A + ++ +A L C LL CV K + + L
Sbjct: 88 SPVCKLVPPHETFGFKVAVIASIVSCAIILLMSMAFLTC-CLLKCVKKSKRRRSNRSAQL 146
Query: 263 PQHLKE---------FLGHPHHNTLLFFSFPLSDENDVFDKLSVIAEDSESGKQNPGDSC 313
LK+ +LG H F+ P+S + D S + ES + +
Sbjct: 147 WSQLKDEDLETVQAAYLGLKH------FNKPVSGPSQAHDNHSFTTDHGESTSKLASVTR 200
Query: 314 SLGTPPG 320
S+ PG
Sbjct: 201 SVDKDPG 207
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 33.9 bits (76), Expect = 0.20
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 1/52 (1%)
Query: 152 WTYNVQYWKNGTDEKFQITPQYDFEV-LRNLEPWTTYCVQVRGFLPDRNKAG 202
W Y V Y K G + + F V L +L P TTY VQV+ + AG
Sbjct: 467 WKYEVTYRKKGDSNSYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAG 518
>gi|4557040 oncostatin M receptor [Homo sapiens]
Length = 979
Score = 32.3 bits (72), Expect = 0.59
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 5/86 (5%)
Query: 138 NEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFE---VLRNLEPWTTYCVQVRGF 194
N TW + ++ N++TY Q +G + Q L LEP T Y +VR
Sbjct: 348 NAIMTWKVHSIRNNFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSELEPATEYMARVR-- 405
Query: 195 LPDRNKAGEWSEPVCEQTTHDETVPS 220
D + +WSE + T E PS
Sbjct: 406 CADASHFWKWSEWSGQNFTTLEAAPS 431
>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 31.6 bits (70), Expect = 1.0
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 8/81 (9%)
Query: 185 TTYCVQVR-GFLPDRNKAG---EWSEPVCEQTTHDETVPSW---MVAVILMASVFMVCLA 237
++Y +QVR G +P + G EWS+PV QT +E W ++ ++L+ VF+
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
Query: 238 LLGCFALLWCVYKKTKYAFSP 258
L LW ++KK SP
Sbjct: 254 SLKTHP-LWRLWKKIWAVPSP 273
>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 31.6 bits (70), Expect = 1.0
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 8/81 (9%)
Query: 185 TTYCVQVR-GFLPDRNKAG---EWSEPVCEQTTHDETVPSW---MVAVILMASVFMVCLA 237
++Y +QVR G +P + G EWS+PV QT +E W ++ ++L+ VF+
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
Query: 238 LLGCFALLWCVYKKTKYAFSP 258
L LW ++KK SP
Sbjct: 254 SLKTHP-LWRLWKKIWAVPSP 273
>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 31.6 bits (70), Expect = 1.0
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 8/81 (9%)
Query: 185 TTYCVQVR-GFLPDRNKAG---EWSEPVCEQTTHDETVPSW---MVAVILMASVFMVCLA 237
++Y +QVR G +P + G EWS+PV QT +E W ++ ++L+ VF+
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
Query: 238 LLGCFALLWCVYKKTKYAFSP 258
L LW ++KK SP
Sbjct: 254 SLKTHP-LWRLWKKIWAVPSP 273
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 30.8 bits (68), Expect = 1.7
Identities = 18/43 (41%), Positives = 26/43 (60%), Gaps = 4/43 (9%)
Query: 178 LRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPS 220
+ +LE WT Y VQV+ F + +G WS+ V +T E+VPS
Sbjct: 1162 IEDLEEWTEYRVQVQAF--NAIGSGPWSQTVVGRTR--ESVPS 1200
>gi|119395738 insulin receptor isoform Short precursor [Homo
sapiens]
Length = 1370
Score = 30.4 bits (67), Expect = 2.2
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 9/75 (12%)
Query: 150 NSWTY-NVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVR---GFLPDRNKAGEWS 205
NSWT ++ D K Q P + ++R L+PWT Y + V+ F +R G S
Sbjct: 554 NSWTVVDIDPPLRSNDPKSQNHPGW---LMRGLKPWTQYAIFVKTLVTFSDERRTYGAKS 610
Query: 206 EPVCEQTTHDETVPS 220
+ + QT D T PS
Sbjct: 611 DIIYVQT--DATNPS 623
>gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]
Length = 1382
Score = 30.4 bits (67), Expect = 2.2
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 9/75 (12%)
Query: 150 NSWTY-NVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVR---GFLPDRNKAGEWS 205
NSWT ++ D K Q P + ++R L+PWT Y + V+ F +R G S
Sbjct: 554 NSWTVVDIDPPLRSNDPKSQNHPGW---LMRGLKPWTQYAIFVKTLVTFSDERRTYGAKS 610
Query: 206 EPVCEQTTHDETVPS 220
+ + QT D T PS
Sbjct: 611 DIIYVQT--DATNPS 623
>gi|31317239 interleukin 22 receptor, alpha 1 [Homo sapiens]
Length = 574
Score = 30.0 bits (66), Expect = 2.9
Identities = 14/57 (24%), Positives = 28/57 (49%), Gaps = 4/57 (7%)
Query: 25 ENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYR----IFQDKCMNTTLTECDFS 77
++V+ S NF+NIL W+S + ++ +Y +Y + + C T C+ +
Sbjct: 26 QHVKFQSSNFENILTWDSGPEGTPDTVYSIEYKTYGERDWVAKKGCQRITRKSCNLT 82
>gi|19924165 proto-oncogene c-ros-1 protein precursor [Homo sapiens]
Length = 2347
Score = 30.0 bits (66), Expect = 2.9
Identities = 40/179 (22%), Positives = 66/179 (36%), Gaps = 28/179 (15%)
Query: 61 IFQDKCM--NTTLTECDFSSLSKYGDHTLRVRAEFADEHS-----DWVNITFCPVDDTII 113
IFQ + N + CD S + ++G L + + H +++ F +
Sbjct: 517 IFQQDALSFNEFIVGCDLSHIEEFGFGNLVIFGSSSQLHPLPGRPQELSVLFGSHQALVQ 576
Query: 114 GPP-----GMQVEVLADSLHMRFLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQ 168
P G V +++D + + L P + + +WTY V+ E
Sbjct: 577 WKPPALAIGANVILISDIIELFELGP------------SAWQNWTYEVKVSTQDPPEVTH 624
Query: 169 ITPQYDFEVLR--NLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTHDETVPSWMVAV 225
I +L L+ Y V VR P R G WSEP T + P +++AV
Sbjct: 625 IFLNISGTMLNVPELQSAMKYKVSVRASSPKR--PGPWSEPSVGTTLVPASEPPFIMAV 681
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
[Homo sapiens]
Length = 1899
Score = 30.0 bits (66), Expect = 2.9
Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 15/68 (22%)
Query: 151 SWT--------YNVQYW--KNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNK 200
SWT Y V+Y+ G ++F ++ VL++L+P T Y V V + D
Sbjct: 240 SWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVED--- 296
Query: 201 AGEWSEPV 208
E+SEP+
Sbjct: 297 --EYSEPL 302
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 30.0 bits (66), Expect = 2.9
Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 15/68 (22%)
Query: 151 SWT--------YNVQYW--KNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNK 200
SWT Y V+Y+ G ++F ++ VL++L+P T Y V V + D
Sbjct: 1404 SWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVED--- 1460
Query: 201 AGEWSEPV 208
E+SEP+
Sbjct: 1461 --EYSEPL 1466
>gi|4507103 small nuclear RNA activating complex, polypeptide 2,
45kDa [Homo sapiens]
Length = 334
Score = 30.0 bits (66), Expect = 2.9
Identities = 16/42 (38%), Positives = 21/42 (50%)
Query: 199 NKAGEWSEPVCEQTTHDETVPSWMVAVILMASVFMVCLALLG 240
+KA E + P E+ H E W A I + F+V L LLG
Sbjct: 286 SKAPEETPPATEKAEHSELKSPWQAAGICPLNPFLVPLELLG 327
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,874,362
Number of Sequences: 37866
Number of extensions: 662188
Number of successful extensions: 1424
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1370
Number of HSP's gapped (non-prelim): 76
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.