BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|240255483 sulfatase 2 isoform a precursor [Homo sapiens] (870 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|240255483 sulfatase 2 isoform a precursor [Homo sapiens] 1834 0.0 gi|29789100 sulfatase 2 isoform a precursor [Homo sapiens] 1834 0.0 gi|240255478 sulfatase 2 isoform b precursor [Homo sapiens] 1823 0.0 gi|189571643 sulfatase 1 [Homo sapiens] 1214 0.0 gi|189571641 sulfatase 1 [Homo sapiens] 1214 0.0 gi|189571638 sulfatase 1 [Homo sapiens] 1214 0.0 gi|189571636 sulfatase 1 [Homo sapiens] 1214 0.0 gi|4504061 glucosamine (N-acetyl)-6-sulfatase precursor [Homo sa... 313 6e-85 gi|39930577 arylsulfatase K [Homo sapiens] 97 8e-20 gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens] 65 3e-10 gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precurso... 65 4e-10 gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens] 64 5e-10 gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens] 64 5e-10 gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens] 64 5e-10 gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens] 64 5e-10 gi|109389362 arylsulfatase J [Homo sapiens] 59 2e-08 gi|59797060 arylsulfatase family, member I [Homo sapiens] 58 4e-08 gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens] 56 1e-07 gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens] 55 2e-07 gi|5360208 iduronate-2-sulfatase isoform b precursor [Homo sapiens] 54 5e-07 gi|53831991 steryl-sulfatase precursor [Homo sapiens] 54 6e-07 gi|4506919 N-sulfoglucosamine sulfohydrolase precursor [Homo sap... 52 2e-06 gi|31742482 arylsulfatase F precursor [Homo sapiens] 49 2e-05 gi|45430057 Arylsulfatase G [Homo sapiens] 49 2e-05 gi|146229327 arylsulfatase A isoform b [Homo sapiens] 48 3e-05 gi|58743319 arylsulfatase family, member H [Homo sapiens] 47 6e-05 gi|71852584 arylsulfatase D isoform a precursor [Homo sapiens] 44 8e-04 gi|71852586 arylsulfatase D isoform b precursor [Homo sapiens] 43 0.001 gi|157266309 arylsulfatase E precursor [Homo sapiens] 40 0.007 gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo sa... 32 2.0 >gi|240255483 sulfatase 2 isoform a precursor [Homo sapiens] Length = 870 Score = 1834 bits (4750), Expect = 0.0 Identities = 870/870 (100%), Positives = 870/870 (100%) Query: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS Sbjct: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60 Query: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA Sbjct: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120 Query: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK Sbjct: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180 Query: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP Sbjct: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240 Query: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM Sbjct: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300 Query: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV Sbjct: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360 Query: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL Sbjct: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420 Query: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP Sbjct: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480 Query: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV Sbjct: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540 Query: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT Sbjct: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600 Query: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC Sbjct: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660 Query: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC Sbjct: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720 Query: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE Sbjct: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780 Query: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 840 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE Sbjct: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 840 Query: 841 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 870 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG Sbjct: 841 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 870 >gi|29789100 sulfatase 2 isoform a precursor [Homo sapiens] Length = 870 Score = 1834 bits (4750), Expect = 0.0 Identities = 870/870 (100%), Positives = 870/870 (100%) Query: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS Sbjct: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60 Query: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA Sbjct: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120 Query: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK Sbjct: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180 Query: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP Sbjct: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240 Query: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM Sbjct: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300 Query: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV Sbjct: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360 Query: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL Sbjct: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420 Query: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP Sbjct: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480 Query: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV Sbjct: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540 Query: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT Sbjct: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600 Query: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC Sbjct: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660 Query: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC Sbjct: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720 Query: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE Sbjct: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780 Query: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 840 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE Sbjct: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 840 Query: 841 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 870 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG Sbjct: 841 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 870 >gi|240255478 sulfatase 2 isoform b precursor [Homo sapiens] Length = 867 Score = 1823 bits (4721), Expect = 0.0 Identities = 867/870 (99%), Positives = 867/870 (99%), Gaps = 3/870 (0%) Query: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS Sbjct: 1 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 60 Query: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA Sbjct: 61 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 120 Query: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK Sbjct: 121 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 180 Query: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP Sbjct: 181 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 240 Query: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM Sbjct: 241 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 300 Query: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV Sbjct: 301 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 360 Query: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL Sbjct: 361 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 420 Query: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP Sbjct: 421 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 480 Query: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV Sbjct: 481 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 540 Query: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT Sbjct: 541 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 600 Query: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC Sbjct: 601 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 660 Query: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC Sbjct: 661 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 720 Query: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE Sbjct: 721 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 780 Query: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 840 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDL DGGSYE Sbjct: 781 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDL---DGGSYE 837 Query: 841 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 870 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG Sbjct: 838 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 867 >gi|189571643 sulfatase 1 [Homo sapiens] Length = 871 Score = 1214 bits (3142), Expect = 0.0 Identities = 579/891 (64%), Positives = 699/891 (78%), Gaps = 51/891 (5%) Query: 5 SLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVM 64 +LVL +L LLG + + R +GR Q++R+NIRPNIILVLTDDQDVELGS+QVM Sbjct: 7 ALVLAVLGT---ELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVM 63 Query: 65 NKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHES 124 NKTR+IME GGA FINAFVTTPMCCPSRSS+LTGKYVHNHN YTNNENCSSPSWQA HE Sbjct: 64 NKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEP 123 Query: 125 RTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHG 184 RTFAVYLN+TGYRTAFFGKYLNEYNGSY+PPGW+EW+GL+KNSRFYNYT+CRNG+KEKHG Sbjct: 124 RTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHG 183 Query: 185 SDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQ 244 DY+KDY TDLITN+S+++F+ SK+MYPHRPV+MVISHAAPHGPEDSAPQ+S+L+PNASQ Sbjct: 184 FDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQ 243 Query: 245 HITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVET 304 HITPSYNYAPN DKHWIM+YTGPM PIHMEFTN+LQRKRLQTLMSVDDS+E +YNMLVET Sbjct: 244 HITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVET 303 Query: 305 GELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNID 364 GEL+NTYI+YTADHGYHIGQFGLVKGKSMPY+FDIRVPF++RGP+VE G + P IVLNID Sbjct: 304 GELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNID 363 Query: 365 LAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRD 424 LAPTILDIAGLD P D+DGKS+LKLLD E+P NRF KK ++WRD+FLVERGK L K++ Sbjct: 364 LAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKE 423 Query: 425 NDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGPMRLG 484 + Q+ N LPKY+RVK+LCQ+A YQTACEQ GQKWQC+ED +GKL++HKCKGP L Sbjct: 424 ESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLL 483 Query: 485 GSR-ALSNLVPKYYGQGSEACTCDSGDYKLSLAGRR-KKLFKK-----KYKASYVRSRSI 537 R + NL + + + C+C Y+ S + R+ ++ F + KYK +V +R Sbjct: 484 TVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQT 543 Query: 538 RSVAIEVDGRVYHVGLGD-----AAQPRNLTKRHWPG--APEDQDDKDGG-------DFS 583 RS+++E +G +Y + L + QPRN+ KRH G P D GG D S Sbjct: 544 RSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSS 603 Query: 584 GTGGLPDYSAANPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIK 643 G P ++VTH+C+IL ND++ C+ +LY+S +AWKDHK +ID EIE LQ+KIK Sbjct: 604 NAVGPP-----TTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIK 658 Query: 644 NLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHR--GSSLHPFRKGLQEKD-KVWLLRE 700 NLREVRGHLK+++PEEC C K SY+ + KG K S LHPF++ QE D K+ L +E Sbjct: 659 NLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKE 718 Query: 701 -QKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWC 759 +R+KK RK +R + + CS+PGLTCFTHDN HWQTAPFW LG FCACTS+NNNTYWC Sbjct: 719 NNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWC 778 Query: 760 MRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGY 819 +RT+NETHNFLFCEFATGFLEYFD+NTDPYQL N V+T++R +LNQLHVQLMELRSC+GY Sbjct: 779 LRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGY 838 Query: 820 KQCNPRTRNMDLGLKDGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 870 KQCNPR +N+D+G KDGGSY+ +R GQLW+GWEG Sbjct: 839 KQCNPRPKNLDVGNKDGGSYDLHR------------------GQLWDGWEG 871 >gi|189571641 sulfatase 1 [Homo sapiens] Length = 871 Score = 1214 bits (3142), Expect = 0.0 Identities = 579/891 (64%), Positives = 699/891 (78%), Gaps = 51/891 (5%) Query: 5 SLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVM 64 +LVL +L LLG + + R +GR Q++R+NIRPNIILVLTDDQDVELGS+QVM Sbjct: 7 ALVLAVLGT---ELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVM 63 Query: 65 NKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHES 124 NKTR+IME GGA FINAFVTTPMCCPSRSS+LTGKYVHNHN YTNNENCSSPSWQA HE Sbjct: 64 NKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEP 123 Query: 125 RTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHG 184 RTFAVYLN+TGYRTAFFGKYLNEYNGSY+PPGW+EW+GL+KNSRFYNYT+CRNG+KEKHG Sbjct: 124 RTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHG 183 Query: 185 SDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQ 244 DY+KDY TDLITN+S+++F+ SK+MYPHRPV+MVISHAAPHGPEDSAPQ+S+L+PNASQ Sbjct: 184 FDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQ 243 Query: 245 HITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVET 304 HITPSYNYAPN DKHWIM+YTGPM PIHMEFTN+LQRKRLQTLMSVDDS+E +YNMLVET Sbjct: 244 HITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVET 303 Query: 305 GELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNID 364 GEL+NTYI+YTADHGYHIGQFGLVKGKSMPY+FDIRVPF++RGP+VE G + P IVLNID Sbjct: 304 GELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNID 363 Query: 365 LAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRD 424 LAPTILDIAGLD P D+DGKS+LKLLD E+P NRF KK ++WRD+FLVERGK L K++ Sbjct: 364 LAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKE 423 Query: 425 NDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGPMRLG 484 + Q+ N LPKY+RVK+LCQ+A YQTACEQ GQKWQC+ED +GKL++HKCKGP L Sbjct: 424 ESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLL 483 Query: 485 GSR-ALSNLVPKYYGQGSEACTCDSGDYKLSLAGRR-KKLFKK-----KYKASYVRSRSI 537 R + NL + + + C+C Y+ S + R+ ++ F + KYK +V +R Sbjct: 484 TVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQT 543 Query: 538 RSVAIEVDGRVYHVGLGD-----AAQPRNLTKRHWPG--APEDQDDKDGG-------DFS 583 RS+++E +G +Y + L + QPRN+ KRH G P D GG D S Sbjct: 544 RSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSS 603 Query: 584 GTGGLPDYSAANPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIK 643 G P ++VTH+C+IL ND++ C+ +LY+S +AWKDHK +ID EIE LQ+KIK Sbjct: 604 NAVGPP-----TTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIK 658 Query: 644 NLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHR--GSSLHPFRKGLQEKD-KVWLLRE 700 NLREVRGHLK+++PEEC C K SY+ + KG K S LHPF++ QE D K+ L +E Sbjct: 659 NLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKE 718 Query: 701 -QKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWC 759 +R+KK RK +R + + CS+PGLTCFTHDN HWQTAPFW LG FCACTS+NNNTYWC Sbjct: 719 NNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWC 778 Query: 760 MRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGY 819 +RT+NETHNFLFCEFATGFLEYFD+NTDPYQL N V+T++R +LNQLHVQLMELRSC+GY Sbjct: 779 LRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGY 838 Query: 820 KQCNPRTRNMDLGLKDGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 870 KQCNPR +N+D+G KDGGSY+ +R GQLW+GWEG Sbjct: 839 KQCNPRPKNLDVGNKDGGSYDLHR------------------GQLWDGWEG 871 >gi|189571638 sulfatase 1 [Homo sapiens] Length = 871 Score = 1214 bits (3142), Expect = 0.0 Identities = 579/891 (64%), Positives = 699/891 (78%), Gaps = 51/891 (5%) Query: 5 SLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVM 64 +LVL +L LLG + + R +GR Q++R+NIRPNIILVLTDDQDVELGS+QVM Sbjct: 7 ALVLAVLGT---ELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVM 63 Query: 65 NKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHES 124 NKTR+IME GGA FINAFVTTPMCCPSRSS+LTGKYVHNHN YTNNENCSSPSWQA HE Sbjct: 64 NKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEP 123 Query: 125 RTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHG 184 RTFAVYLN+TGYRTAFFGKYLNEYNGSY+PPGW+EW+GL+KNSRFYNYT+CRNG+KEKHG Sbjct: 124 RTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHG 183 Query: 185 SDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQ 244 DY+KDY TDLITN+S+++F+ SK+MYPHRPV+MVISHAAPHGPEDSAPQ+S+L+PNASQ Sbjct: 184 FDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQ 243 Query: 245 HITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVET 304 HITPSYNYAPN DKHWIM+YTGPM PIHMEFTN+LQRKRLQTLMSVDDS+E +YNMLVET Sbjct: 244 HITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVET 303 Query: 305 GELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNID 364 GEL+NTYI+YTADHGYHIGQFGLVKGKSMPY+FDIRVPF++RGP+VE G + P IVLNID Sbjct: 304 GELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNID 363 Query: 365 LAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRD 424 LAPTILDIAGLD P D+DGKS+LKLLD E+P NRF KK ++WRD+FLVERGK L K++ Sbjct: 364 LAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKE 423 Query: 425 NDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGPMRLG 484 + Q+ N LPKY+RVK+LCQ+A YQTACEQ GQKWQC+ED +GKL++HKCKGP L Sbjct: 424 ESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLL 483 Query: 485 GSR-ALSNLVPKYYGQGSEACTCDSGDYKLSLAGRR-KKLFKK-----KYKASYVRSRSI 537 R + NL + + + C+C Y+ S + R+ ++ F + KYK +V +R Sbjct: 484 TVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQT 543 Query: 538 RSVAIEVDGRVYHVGLGD-----AAQPRNLTKRHWPG--APEDQDDKDGG-------DFS 583 RS+++E +G +Y + L + QPRN+ KRH G P D GG D S Sbjct: 544 RSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSS 603 Query: 584 GTGGLPDYSAANPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIK 643 G P ++VTH+C+IL ND++ C+ +LY+S +AWKDHK +ID EIE LQ+KIK Sbjct: 604 NAVGPP-----TTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIK 658 Query: 644 NLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHR--GSSLHPFRKGLQEKD-KVWLLRE 700 NLREVRGHLK+++PEEC C K SY+ + KG K S LHPF++ QE D K+ L +E Sbjct: 659 NLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKE 718 Query: 701 -QKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWC 759 +R+KK RK +R + + CS+PGLTCFTHDN HWQTAPFW LG FCACTS+NNNTYWC Sbjct: 719 NNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWC 778 Query: 760 MRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGY 819 +RT+NETHNFLFCEFATGFLEYFD+NTDPYQL N V+T++R +LNQLHVQLMELRSC+GY Sbjct: 779 LRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGY 838 Query: 820 KQCNPRTRNMDLGLKDGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 870 KQCNPR +N+D+G KDGGSY+ +R GQLW+GWEG Sbjct: 839 KQCNPRPKNLDVGNKDGGSYDLHR------------------GQLWDGWEG 871 >gi|189571636 sulfatase 1 [Homo sapiens] Length = 871 Score = 1214 bits (3142), Expect = 0.0 Identities = 579/891 (64%), Positives = 699/891 (78%), Gaps = 51/891 (5%) Query: 5 SLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVM 64 +LVL +L LLG + + R +GR Q++R+NIRPNIILVLTDDQDVELGS+QVM Sbjct: 7 ALVLAVLGT---ELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVM 63 Query: 65 NKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHES 124 NKTR+IME GGA FINAFVTTPMCCPSRSS+LTGKYVHNHN YTNNENCSSPSWQA HE Sbjct: 64 NKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEP 123 Query: 125 RTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHG 184 RTFAVYLN+TGYRTAFFGKYLNEYNGSY+PPGW+EW+GL+KNSRFYNYT+CRNG+KEKHG Sbjct: 124 RTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHG 183 Query: 185 SDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQ 244 DY+KDY TDLITN+S+++F+ SK+MYPHRPV+MVISHAAPHGPEDSAPQ+S+L+PNASQ Sbjct: 184 FDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQ 243 Query: 245 HITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVET 304 HITPSYNYAPN DKHWIM+YTGPM PIHMEFTN+LQRKRLQTLMSVDDS+E +YNMLVET Sbjct: 244 HITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVET 303 Query: 305 GELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNID 364 GEL+NTYI+YTADHGYHIGQFGLVKGKSMPY+FDIRVPF++RGP+VE G + P IVLNID Sbjct: 304 GELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNID 363 Query: 365 LAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRD 424 LAPTILDIAGLD P D+DGKS+LKLLD E+P NRF KK ++WRD+FLVERGK L K++ Sbjct: 364 LAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKE 423 Query: 425 NDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGPMRLG 484 + Q+ N LPKY+RVK+LCQ+A YQTACEQ GQKWQC+ED +GKL++HKCKGP L Sbjct: 424 ESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLL 483 Query: 485 GSR-ALSNLVPKYYGQGSEACTCDSGDYKLSLAGRR-KKLFKK-----KYKASYVRSRSI 537 R + NL + + + C+C Y+ S + R+ ++ F + KYK +V +R Sbjct: 484 TVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQT 543 Query: 538 RSVAIEVDGRVYHVGLGD-----AAQPRNLTKRHWPG--APEDQDDKDGG-------DFS 583 RS+++E +G +Y + L + QPRN+ KRH G P D GG D S Sbjct: 544 RSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSS 603 Query: 584 GTGGLPDYSAANPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIK 643 G P ++VTH+C+IL ND++ C+ +LY+S +AWKDHK +ID EIE LQ+KIK Sbjct: 604 NAVGPP-----TTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIK 658 Query: 644 NLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHR--GSSLHPFRKGLQEKD-KVWLLRE 700 NLREVRGHLK+++PEEC C K SY+ + KG K S LHPF++ QE D K+ L +E Sbjct: 659 NLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKE 718 Query: 701 -QKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWC 759 +R+KK RK +R + + CS+PGLTCFTHDN HWQTAPFW LG FCACTS+NNNTYWC Sbjct: 719 NNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWC 778 Query: 760 MRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGY 819 +RT+NETHNFLFCEFATGFLEYFD+NTDPYQL N V+T++R +LNQLHVQLMELRSC+GY Sbjct: 779 LRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGY 838 Query: 820 KQCNPRTRNMDLGLKDGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 870 KQCNPR +N+D+G KDGGSY+ +R GQLW+GWEG Sbjct: 839 KQCNPRPKNLDVGNKDGGSYDLHR------------------GQLWDGWEG 871 >gi|4504061 glucosamine (N-acetyl)-6-sulfatase precursor [Homo sapiens] Length = 552 Score = 313 bits (801), Expect = 6e-85 Identities = 170/359 (47%), Positives = 218/359 (60%), Gaps = 15/359 (4%) Query: 43 RPNIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVH 102 RPN++L+LTDDQD LG M + KT+ ++ + G F +A+V + +CCPSR+SILTGKY H Sbjct: 46 RPNVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPH 105 Query: 103 NHNTYTNN--ENCSSPSWQAQHESRTFAVYLNST-GYRTAFFGKYLNEYNG------SYV 153 NH+ N NCSS SWQ E TF L S GY+T F GKYLNEY +V Sbjct: 106 NHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHV 165 Query: 154 PPGWKEWVGLLKNSRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPH 213 P GW W L KNS++YNYTL NG KHG +YS DYLTD++ N S+ F Sbjct: 166 PLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNF--- 222 Query: 214 RPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTG-PMKPIH 272 P M+I+ APH P +APQY + F N ++N +KHW++R PM Sbjct: 223 EPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIH-GTNKHWLIRQAKTPMTNSS 281 Query: 273 MEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHIGQFGLVKGKS 332 ++F + RKR QTL+SVDD +E + L TGEL+NTYI YT+D+GYH GQF L K Sbjct: 282 IQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKR 341 Query: 333 MPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDI-PADMDGKSILKLL 390 YEFDI+VP VRGP ++ + +V NIDL PTILDIAG D+ MDG S+L +L Sbjct: 342 QLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPIL 400 Score = 67.8 bits (164), Expect = 4e-11 Identities = 31/76 (40%), Positives = 47/76 (61%), Gaps = 2/76 (2%) Query: 745 PFCACTSANNNTYWCMRTINETHNFLFCEFATG--FLEYFDLNTDPYQLMNAVNTLDRDV 802 P C C A NNTY C+RT++ N +CEF F+E ++L DP Q+ N T+D ++ Sbjct: 440 PDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYNLTADPDQITNIAKTIDPEL 499 Query: 803 LNQLHVQLMELRSCKG 818 L +++ +LM L+SC G Sbjct: 500 LGKMNYRLMMLQSCSG 515 >gi|39930577 arylsulfatase K [Homo sapiens] Length = 536 Score = 96.7 bits (239), Expect = 8e-20 Identities = 98/382 (25%), Positives = 170/382 (44%), Gaps = 49/382 (12%) Query: 36 QRDRRNIRPNIILVLTDDQDVEL----GSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPS 91 QR R PN++LV++D D L GS V M+ G F+NA+ +P+CCPS Sbjct: 24 QRRRAAKAPNVVLVVSDSFDGRLTFHPGSQVVKLPFINFMKTRGTSFLNAYTNSPICCPS 83 Query: 92 RSSILTGKYVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGK--YLNEYN 149 R+++ +G + H ++ NN P++ T+ + GYRT FGK Y + ++ Sbjct: 84 RAAMWSGLFTHLTESW-NNFKGLDPNY------TTWMDVMERHGYRTQKFGKLDYTSGHH 136 Query: 150 --GSYVPPGWKEWVGLLKNSRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTS 207 + V ++ LL+ L RN K + +D+ T+ +V++ R Sbjct: 137 SISNRVEAWTRDVAFLLRQEGRPMVNLIRNRTKVR---VMERDWQN---TDKAVNWLRKE 190 Query: 208 KKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSY------------NYAPN 255 Y P ++ + PH P S P F +++ H + + ++P Sbjct: 191 AINYT-EPFVIYLGLNLPH-PYPS-PSSGENFGSSTFHTSLYWLEKVSHDAIKIPKWSPL 247 Query: 256 PDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMS--------VDDSMETIYNMLVETGEL 307 + H + Y+ K FT +K ++ + + D + I L + L Sbjct: 248 SEMHPVDYYSSYTKNCTGRFT----KKEIKNIRAFYYAMCAETDAMLGEIILALHQLDLL 303 Query: 308 DNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAP 367 T ++Y++DHG + SM YE VP + GP ++AG ++V +D+ P Sbjct: 304 QKTIVIYSSDHGELAMEHRQFYKMSM-YEASAHVPLLMMGPGIKAGLQVSNVVSLVDIYP 362 Query: 368 TILDIAGLDIPADMDGKSILKL 389 T+LDIAG+ +P ++ G S+L L Sbjct: 363 TMLDIAGIPLPQNLSGYSLLPL 384 Score = 30.4 bits (67), Expect = 7.4 Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 5/81 (6%) Query: 715 QNNDTCSMPGLTCFTHDNQHW--QTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFC 772 QN S+ L+ T N+H P W L F C + N +TY M N + Sbjct: 374 QNLSGYSLLPLSSETFKNEHKVKNLHPPWILSEFHGC-NVNASTY--MLRTNHWKYIAYS 430 Query: 773 EFATGFLEYFDLNTDPYQLMN 793 + A+ + FDL++DP +L N Sbjct: 431 DGASILPQLFDLSSDPDELTN 451 >gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens] Length = 550 Score = 65.1 bits (157), Expect = 3e-10 Identities = 92/447 (20%), Positives = 161/447 (36%), Gaps = 84/447 (18%) Query: 45 NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAH---FINAFVTTPMCCPSRSSILTGKYV 101 N++L++ DD LG ++Q +H F NAF +C PSR S LTG+ Sbjct: 38 NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97 Query: 102 HNHNTYTNNENCSSPSWQAQHES-RTFAVYLNSTGYRTAFFGKY----LNEYNGSYVPPG 156 Y N W+ + T Y GY T GK ++ + P Sbjct: 98 DTTRLYDFNSY-----WRVHAGNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYS 152 Query: 157 WKEWVGLLKNSRFYNYTLCRNGVKEKHGS--------DYSKDYLTDLITNDSVSFFRTSK 208 W + ++ N CR E H + D + L D + + + K Sbjct: 153 WSFPPYHPSSEKYENTKTCRGPDGELHANLLCPVDVLDVPEGTLPDKQSTEQ-AIQLLEK 211 Query: 209 KMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYA----PNPDKHWI--- 261 P + + + PH P ++ +L+P + + P P W+ Sbjct: 212 MKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIR 271 Query: 262 -------MRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVY 314 + + P PI ++F +++ ++ +D + + + L + ++T I + Sbjct: 272 QREDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAF 331 Query: 315 TADHGYHIGQFG-LVKGKSMPYEFDIRVPFYVRGPN-----------------------V 350 T+DHG+ +G+ G K + + + FYV G + Sbjct: 332 TSDHGWALGEHGEWAKYSNFDVATHVPLIFYVPGRTASLPEAGEKLFPYLDPFDSASQLM 391 Query: 351 EAGCLNPHIVLNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRD 410 E G + +V + L PT+ +AGL +P PV FH++ Sbjct: 392 EPGRQSMDLVELVSLFPTLAGLAGLQVP-------------PRCPVPSFHVE-------- 430 Query: 411 SFLVERGKLLHKRDNDKVDAQEENFLP 437 L GK L K + D +E+ +LP Sbjct: 431 --LCREGKNLLKHFRFR-DLEEDPYLP 454 >gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precursor [Homo sapiens] Length = 522 Score = 64.7 bits (156), Expect = 4e-10 Identities = 97/396 (24%), Positives = 152/396 (38%), Gaps = 87/396 (21%) Query: 44 PNIILVLTDDQDV-ELG-----SMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILT 97 PNI+L+L DD +LG S + N R E G F N + P+C PSR+++LT Sbjct: 31 PNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAE--GLLFPNFYSANPLCSPSRAALLT 88 Query: 98 GKYVHNHNTYTNNENCSSPSWQAQ------HESRTFAVYLNSTGYRTAFFGKYLNEYNGS 151 G+ + YT N + + + + L GY + GK+ + Sbjct: 89 GRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQ 148 Query: 152 YVP--PGWKEWVGLLKNSRFYNY-TLCRNGVK-----EKHGSDYSK---------DYLTD 194 + P G+ EW G N F Y R + E G Y + LT Sbjct: 149 FHPLKHGFDEWFGS-PNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQ 207 Query: 195 LITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAP 254 + +++ F K+ H P + + A H P YA Sbjct: 208 IYLQEALDFI---KRQARHHPFFLYWAVDATHAPV----------------------YAS 242 Query: 255 NPDKHWIMRYTGPMKPIHMEFTNMLQRKRL-QTLMSVDDSMETIYNMLVETGELDNTYIV 313 P F QR R + +DDS+ I +L + DNT++ Sbjct: 243 KP------------------FLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFVF 284 Query: 314 YTADHGYHI-------GQFG-LVKGKSMPYEFDIRVPFYVRGP-NVEAGCLNPHIVLNID 364 +T+D+G + G G + GK +E +R P P +V AG ++ + +D Sbjct: 285 FTSDNGAALISAPEQGGSNGPFLCGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMD 344 Query: 365 LAPTILDIAGLDIPAD--MDGKSILKLLDTERPVNR 398 L T L +AGL P+D +DG ++L L R ++R Sbjct: 345 LFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDR 380 >gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens] Length = 507 Score = 64.3 bits (155), Expect = 5e-10 Identities = 92/367 (25%), Positives = 150/367 (40%), Gaps = 45/367 (12%) Query: 44 PNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSILTGK 99 PNI+L+ DD +LG + T ++Q GG F + +V +C PSR+++LTG+ Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80 Query: 100 YVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYN--GSYVPP-- 155 Y SS E T A L + GY T GK+ G+++PP Sbjct: 81 LPVRMGMYPGVLVPSSRGGLPLEEV-TVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQ 139 Query: 156 GWKEWVGLLKN---SRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYP 212 G+ ++G+ + N T G D + L+ N SV + P Sbjct: 140 GFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIP-LLANLSV------EAQPP 192 Query: 213 HRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIH 272 P L A H L +A + P + Y + H+ +++G Sbjct: 193 WLPGLEARYMAFAHD----------LMADAQRQDRPFFLYYASHHTHY-PQFSG------ 235 Query: 273 MEFTNMLQRKRL-QTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHI------GQF 325 F R +LM +D ++ T+ + + G L+ T +++TAD+G G Sbjct: 236 QSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCS 295 Query: 326 GLVK-GKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIP-ADMDG 383 GL++ GK YE +R P P A + + ++DL PT+ +AG +P +DG Sbjct: 296 GLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDG 355 Query: 384 KSILKLL 390 + LL Sbjct: 356 FDLSPLL 362 >gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens] Length = 507 Score = 64.3 bits (155), Expect = 5e-10 Identities = 92/367 (25%), Positives = 150/367 (40%), Gaps = 45/367 (12%) Query: 44 PNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSILTGK 99 PNI+L+ DD +LG + T ++Q GG F + +V +C PSR+++LTG+ Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80 Query: 100 YVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYN--GSYVPP-- 155 Y SS E T A L + GY T GK+ G+++PP Sbjct: 81 LPVRMGMYPGVLVPSSRGGLPLEEV-TVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQ 139 Query: 156 GWKEWVGLLKN---SRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYP 212 G+ ++G+ + N T G D + L+ N SV + P Sbjct: 140 GFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIP-LLANLSV------EAQPP 192 Query: 213 HRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIH 272 P L A H L +A + P + Y + H+ +++G Sbjct: 193 WLPGLEARYMAFAHD----------LMADAQRQDRPFFLYYASHHTHY-PQFSG------ 235 Query: 273 MEFTNMLQRKRL-QTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHI------GQF 325 F R +LM +D ++ T+ + + G L+ T +++TAD+G G Sbjct: 236 QSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCS 295 Query: 326 GLVK-GKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIP-ADMDG 383 GL++ GK YE +R P P A + + ++DL PT+ +AG +P +DG Sbjct: 296 GLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDG 355 Query: 384 KSILKLL 390 + LL Sbjct: 356 FDLSPLL 362 >gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens] Length = 507 Score = 64.3 bits (155), Expect = 5e-10 Identities = 92/367 (25%), Positives = 150/367 (40%), Gaps = 45/367 (12%) Query: 44 PNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSILTGK 99 PNI+L+ DD +LG + T ++Q GG F + +V +C PSR+++LTG+ Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80 Query: 100 YVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYN--GSYVPP-- 155 Y SS E T A L + GY T GK+ G+++PP Sbjct: 81 LPVRMGMYPGVLVPSSRGGLPLEEV-TVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQ 139 Query: 156 GWKEWVGLLKN---SRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYP 212 G+ ++G+ + N T G D + L+ N SV + P Sbjct: 140 GFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIP-LLANLSV------EAQPP 192 Query: 213 HRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIH 272 P L A H L +A + P + Y + H+ +++G Sbjct: 193 WLPGLEARYMAFAHD----------LMADAQRQDRPFFLYYASHHTHY-PQFSG------ 235 Query: 273 MEFTNMLQRKRL-QTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHI------GQF 325 F R +LM +D ++ T+ + + G L+ T +++TAD+G G Sbjct: 236 QSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCS 295 Query: 326 GLVK-GKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIP-ADMDG 383 GL++ GK YE +R P P A + + ++DL PT+ +AG +P +DG Sbjct: 296 GLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDG 355 Query: 384 KSILKLL 390 + LL Sbjct: 356 FDLSPLL 362 >gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens] Length = 507 Score = 64.3 bits (155), Expect = 5e-10 Identities = 92/367 (25%), Positives = 150/367 (40%), Gaps = 45/367 (12%) Query: 44 PNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSILTGK 99 PNI+L+ DD +LG + T ++Q GG F + +V +C PSR+++LTG+ Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80 Query: 100 YVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYN--GSYVPP-- 155 Y SS E T A L + GY T GK+ G+++PP Sbjct: 81 LPVRMGMYPGVLVPSSRGGLPLEEV-TVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQ 139 Query: 156 GWKEWVGLLKN---SRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYP 212 G+ ++G+ + N T G D + L+ N SV + P Sbjct: 140 GFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIP-LLANLSV------EAQPP 192 Query: 213 HRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIH 272 P L A H L +A + P + Y + H+ +++G Sbjct: 193 WLPGLEARYMAFAHD----------LMADAQRQDRPFFLYYASHHTHY-PQFSG------ 235 Query: 273 MEFTNMLQRKRL-QTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHI------GQF 325 F R +LM +D ++ T+ + + G L+ T +++TAD+G G Sbjct: 236 QSFAERSGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCS 295 Query: 326 GLVK-GKSMPYEFDIRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIP-ADMDG 383 GL++ GK YE +R P P A + + ++DL PT+ +AG +P +DG Sbjct: 296 GLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDG 355 Query: 384 KSILKLL 390 + LL Sbjct: 356 FDLSPLL 362 >gi|109389362 arylsulfatase J [Homo sapiens] Length = 599 Score = 58.9 bits (141), Expect = 2e-08 Identities = 86/373 (23%), Positives = 144/373 (38%), Gaps = 73/373 (19%) Query: 43 RPNIILVLTDDQ---DVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGK 99 +P++I +L DDQ DV ++ T + G N +V P+C PSRS +TGK Sbjct: 75 QPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQ-PICTPSRSQFITGK 133 Query: 100 Y-VHNHNTYT----NNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKY-LNEYNGSYV 153 Y +H ++ NC ++ T L GY T GK+ L Y + Sbjct: 134 YQIHTGLQHSIIRPTQPNC------LPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECM 187 Query: 154 PP--GWKEWVGLLKNSRFYNYT--------LCRNGVKEKHGSDYSKD---YLTDLITNDS 200 P G+ + G L S Y YT +C + E + + D Y T + T Sbjct: 188 PTRRGFDTFFGSLLGSGDY-YTHYKCDSPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRV 246 Query: 201 VSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHW 260 + P +P+ + I++ A H P + +Y +H Sbjct: 247 QQILASHN---PTKPIFLYIAYQAVHSPLQAPGRYF-------EH--------------- 281 Query: 261 IMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGY 320 + N+ +R+ L +D+++ + L G +N+ I+Y++D+G Sbjct: 282 -----------YRSIININRRRYAAMLSCLDEAINNVTLALKTYGFYNNSIIIYSSDNGG 330 Query: 321 HIGQFG----LVKGKSMPYEFDIRVPFYVRGPNVE-AGCLNPHIVLNIDLAPTILDIAGL 375 G L K +E IR +V P ++ G + +V D PT++ +A Sbjct: 331 QPTAGGSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEG 390 Query: 376 DIPAD--MDGKSI 386 I D +DG I Sbjct: 391 QIDEDIQLDGYDI 403 >gi|59797060 arylsulfatase family, member I [Homo sapiens] Length = 569 Score = 57.8 bits (138), Expect = 4e-08 Identities = 84/355 (23%), Positives = 139/355 (39%), Gaps = 66/355 (18%) Query: 44 PNIILVLTDDQ---DVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKY 100 P+II +LTDDQ DV + T + G N ++ P+C PSRS +LTG+Y Sbjct: 47 PHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAKGVKLENYYIQ-PICTPSRSQLLTGRY 105 Query: 101 -VH---NHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGK-YLNEYNGSYVPP 155 +H H+ + P Q T L GY T GK +L Y +P Sbjct: 106 QIHTGLQHSIIRPQQPNCLPLDQV-----TLPQKLQEAGYSTHMVGKWHLGFYRKECLPT 160 Query: 156 --GWKEWVG-LLKNSRFYNYTLCRN----GVKEKHGSD----YSKDYLTDLITNDSVSFF 204 G+ ++G L N +Y Y C G G + S Y T L + Sbjct: 161 RRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHIL 220 Query: 205 RTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRY 264 + P RP+ + ++ A H P S +Y + RY Sbjct: 221 ASHS---PQRPLFLYVAFQAVHTPLQSPREY-------------------------LYRY 252 Query: 265 TGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHG---YH 321 N+ +RK + +D+++ I L G +N+ I++++D+G + Sbjct: 253 --------RTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFS 304 Query: 322 IGQFGLVKGKSMPY-EFDIRVPFYVRGPNVEAGCLNPHIVLNI-DLAPTILDIAG 374 G ++G+ Y E +R +V P ++ +++I D PT++ +AG Sbjct: 305 GGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTSRALMHITDWYPTLVGLAG 359 >gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens] Length = 533 Score = 56.2 bits (134), Expect = 1e-07 Identities = 92/429 (21%), Positives = 165/429 (38%), Gaps = 84/429 (19%) Query: 44 PNIILVLTDD---QDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKY 100 P+++ +L DD DV ++ + GG ++ + T P+C PSRS +LTG+Y Sbjct: 45 PHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGV-LLDNYYTQPLCTPSRSQLLTGRY 103 Query: 101 VHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGK-YLNEYNGSYVPP--GW 157 PS E + L GY T GK +L Y +P G+ Sbjct: 104 QIRTGLQHQIIWPCQPSCVPLDE-KLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGF 162 Query: 158 KEWVGLLKNSRFY------------NYTLC----RNGVKEKHGSDYSKDYLTDLITNDSV 201 + G L S Y N T C R+G E+ + Y Y T++ T ++ Sbjct: 163 DTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDG--EEVATGYKNMYSTNIFTKRAI 220 Query: 202 SFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWI 261 + P +P+ + ++ + H P +Y + Y++ + ++H Sbjct: 221 ALITNHP---PEKPLFLYLALQSVHEPLQVPEEYLK-----------PYDFIQDKNRH-- 264 Query: 262 MRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYH 321 Y G + +LM D+++ + L +G +NT +++ D+G Sbjct: 265 -HYAG-----------------MVSLM--DEAVGNVTAALKSSGLWNNTVFIFSTDNG-- 302 Query: 322 IGQFGLVKGKSMP--------YEFDIRVPFYVRGPNV-EAGCLNPHIVLNIDLAPTILDI 372 GQ L G + P +E +R +V P + + G N ++ D PT++ + Sbjct: 303 -GQ-TLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL 360 Query: 373 A--GLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLLHKRDNDKVDA 430 A + +DG + K + P R L + D V+ N A Sbjct: 361 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNI----DPNFVDSSPCPR---NSMAPA 413 Query: 431 QEENFLPKY 439 ++++ LP+Y Sbjct: 414 KDDSSLPEY 422 >gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens] Length = 413 Score = 55.5 bits (132), Expect = 2e-07 Identities = 85/391 (21%), Positives = 151/391 (38%), Gaps = 77/391 (19%) Query: 44 PNIILVLTDD---QDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKY 100 P+++ +L DD DV ++ + GG ++ + T P+C PSRS +LTG+Y Sbjct: 45 PHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGV-LLDNYYTQPLCTPSRSQLLTGRY 103 Query: 101 VHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGK-YLNEYNGSYVPP--GW 157 PS E + L GY T GK +L Y +P G+ Sbjct: 104 QIRTGLQHQIIWPCQPSCVPLDE-KLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGF 162 Query: 158 KEWVGLLKNSRFY------------NYTLC----RNGVKEKHGSDYSKDYLTDLITNDSV 201 + G L S Y N T C R+G E+ + Y Y T++ T ++ Sbjct: 163 DTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDG--EEVATGYKNMYSTNIFTKRAI 220 Query: 202 SFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWI 261 + P +P+ + ++ + H P +Y + Y++ + ++H Sbjct: 221 ALITNHP---PEKPLFLYLALQSVHEPLQVPEEYLK-----------PYDFIQDKNRH-- 264 Query: 262 MRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYH 321 Y G + +LM D+++ + L +G +NT +++ D+G Sbjct: 265 -HYAG-----------------MVSLM--DEAVGNVTAALKSSGLWNNTVFIFSTDNG-- 302 Query: 322 IGQFGLVKGKSMP--------YEFDIRVPFYVRGPNV-EAGCLNPHIVLNIDLAPTILDI 372 GQ L G + P +E +R +V P + + G N ++ D PT++ + Sbjct: 303 -GQ-TLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL 360 Query: 373 A--GLDIPADMDGKSILKLLDTERPVNRFHL 401 A + +DG + K + P R L Sbjct: 361 ARGHTNGTKPLDGFDVWKTISEGSPSPRIEL 391 >gi|5360208 iduronate-2-sulfatase isoform b precursor [Homo sapiens] Length = 343 Score = 54.3 bits (129), Expect = 5e-07 Identities = 62/306 (20%), Positives = 113/306 (36%), Gaps = 36/306 (11%) Query: 45 NIILVLTDDQDVELGSMQVMNKTRRIMEQGGAH---FINAFVTTPMCCPSRSSILTGKYV 101 N++L++ DD LG ++Q +H F NAF +C PSR S LTG+ Sbjct: 38 NVLLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRP 97 Query: 102 HNHNTYTNNENCSSPSWQAQHES-RTFAVYLNSTGYRTAFFGKY----LNEYNGSYVPPG 156 Y N W+ + T Y GY T GK ++ + P Sbjct: 98 DTTRLYDFNSY-----WRVHAGNFSTIPQYFKENGYVTMSVGKVFHPGISSNHTDDSPYS 152 Query: 157 WKEWVGLLKNSRFYNYTLCRNGVKEKHGS--------DYSKDYLTDLITNDSVSFFRTSK 208 W + ++ N CR E H + D + L D + + + K Sbjct: 153 WSFPPYHPSSEKYENTKTCRGPDGELHANLLCPVDVLDVPEGTLPDKQSTEQ-AIQLLEK 211 Query: 209 KMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYA----PNPDKHWI--- 261 P + + + PH P ++ +L+P + + P P W+ Sbjct: 212 MKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVPDGLPPVAYNPWMDIR 271 Query: 262 -------MRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVY 314 + + P PI ++F +++ ++ +D + + + L + ++T I + Sbjct: 272 QREDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSALDDLQLANSTIIAF 331 Query: 315 TADHGY 320 T+DHG+ Sbjct: 332 TSDHGF 337 >gi|53831991 steryl-sulfatase precursor [Homo sapiens] Length = 583 Score = 53.9 bits (128), Expect = 6e-07 Identities = 39/117 (33%), Positives = 62/117 (52%), Gaps = 15/117 (12%) Query: 290 VDDSMETIYNMLVETGELDNTYIVYTADHGYHI-----------GQFGLVK-GKSMPYEF 337 +D S+ I N+L E ++T I +T+D G H+ G G+ K GK+ +E Sbjct: 315 MDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGKANNWEG 374 Query: 338 DIRVPFYVRGPNV-EAGCLNPHIVLNIDLAPTILDIAGLDIPAD--MDGKSILKLLD 391 IRVP +R P V +AG N+D+ PT+ +AG +P D +DG+ ++ LL+ Sbjct: 375 GIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGRDLMPLLE 431 Score = 47.8 bits (112), Expect = 5e-05 Identities = 32/110 (29%), Positives = 48/110 (43%), Gaps = 8/110 (7%) Query: 43 RPNIILVLTDDQDVE----LGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTG 98 RPNIILV+ DD + G+ + + GG +P+C PSR++ +TG Sbjct: 26 RPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTG 85 Query: 99 KYVHNHN----TYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKY 144 +Y + T ++ S + TFA L GY TA GK+ Sbjct: 86 RYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKW 135 >gi|4506919 N-sulfoglucosamine sulfohydrolase precursor [Homo sapiens] Length = 502 Score = 52.0 bits (123), Expect = 2e-06 Identities = 82/368 (22%), Positives = 139/368 (37%), Gaps = 55/368 (14%) Query: 45 NIILVLTDDQDVELGSMQ---VMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYV 101 N +L+L DD E G+ + + + F NAF + C PSR+S+LTG Sbjct: 24 NALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGLPQ 83 Query: 102 HNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWV 161 H + Y +++ + + + R+ + L+ G RT GK +V P E V Sbjct: 84 HQNGMYGLHQDVH--HFNSFDKVRSLPLLLSQAGVRTGIIGK-------KHVGP---ETV 131 Query: 162 GLLKNSRFYNYTLCRNGVKEKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVIS 221 + YT NG + G + ++ L R + RP + ++ Sbjct: 132 YPFD----FAYTE-ENGSVLQVGRNITRIKL----------LVRKFLQTQDDRPFFLYVA 176 Query: 222 HAAPHGPEDSAPQYSRL---FPNASQHI--TPSYNYAPNPDKHWIMRYTGPMKPIHMEFT 276 PH S PQY F N + P + ++ Y P P Sbjct: 177 FHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPA----A 232 Query: 277 NMLQRKRLQTLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYE 336 + T+ +D + + L + G L++T +++T+D+G G++ Y Sbjct: 233 RADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNG-----IPFPSGRTNLYW 287 Query: 337 FDIRVPFYVRGPN--VEAGCLNPHIVLNIDLAPTILDIAGLDIPA---------DMDGKS 385 P V P G ++ V +DL PTILD + P+ + G+S Sbjct: 288 PGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRS 347 Query: 386 ILKLLDTE 393 +L L+ E Sbjct: 348 LLPALEAE 355 >gi|31742482 arylsulfatase F precursor [Homo sapiens] Length = 590 Score = 49.3 bits (116), Expect = 2e-05 Identities = 38/116 (32%), Positives = 60/116 (51%), Gaps = 15/116 (12%) Query: 290 VDDSMETIYNMLVETGELDNTYIVYTADHGYHI----------GQFGLVK-GKSM-PYEF 337 +D + I + + + G +NT + +T+DHG H+ G G+ K GK M +E Sbjct: 318 MDSMVGKILDAIDDFGLRNNTLVYFTSDHGGHLEARRGHAQLGGWNGIYKGGKGMGGWEG 377 Query: 338 DIRVPFYVRGP-NVEAGCLNPHIVLNIDLAPTILDIAGLDIPAD--MDGKSILKLL 390 IRVP VR P V AG L +D+ PT+ ++G +P D +DG+ ++ LL Sbjct: 378 GIRVPGIVRWPGKVPAGRLIKEPTSLMDILPTVASVSGGSLPQDRVIDGRDLMPLL 433 Score = 42.7 bits (99), Expect = 0.001 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 14/113 (12%) Query: 43 RPNIILVLTDDQDV-ELGSMQVMNKTRRI-----MEQGGAHFINAFVTTPMCCPSRSSIL 96 +PNI+L++ DD + +LG N T R + + G +C PSRS+ L Sbjct: 29 KPNIVLIMVDDLGIGDLGCYG--NDTMRTPHIDRLAREGVRLTQHISAASLCSPSRSAFL 86 Query: 97 TGKYVHNHNTYTNN-----ENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKY 144 TG+Y ++ +N + P+ +E+ T A L GY T GK+ Sbjct: 87 TGRYPIRSGMVSSGNRRVIQNLAVPAGLPLNET-TLAALLKKQGYSTGLIGKW 138 >gi|45430057 Arylsulfatase G [Homo sapiens] Length = 525 Score = 48.9 bits (115), Expect = 2e-05 Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 6/119 (5%) Query: 40 RNIRPNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSI 95 R +PN +++L DD +LG+ K +++ G F++ C PSR+S+ Sbjct: 32 RGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASL 91 Query: 96 LTGKYVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVP 154 LTG+ + N T N +S +E+ T A L GY T GK+ ++GSY P Sbjct: 92 LTGR-LGLRNGVTRNFAVTSVGGLPLNET-TLAEVLQQAGYVTGIIGKWHLGHHGSYHP 148 >gi|146229327 arylsulfatase A isoform b [Homo sapiens] Length = 423 Score = 48.1 bits (113), Expect = 3e-05 Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 8/113 (7%) Query: 286 TLMSVDDSMETIYNMLVETGELDNTYIVYTADHGYHI------GQFGLVK-GKSMPYEFD 338 +LM +D ++ T+ + + G L+ T +++TAD+G G GL++ GK YE Sbjct: 166 SLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSGLLRCGKGTTYEGG 225 Query: 339 IRVPFYVRGPNVEAGCLNPHIVLNIDLAPTILDIAGLDIP-ADMDGKSILKLL 390 +R P P A + + ++DL PT+ +AG +P +DG + LL Sbjct: 226 VREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAPLPNVTLDGFDLSPLL 278 >gi|58743319 arylsulfatase family, member H [Homo sapiens] Length = 562 Score = 47.4 bits (111), Expect = 6e-05 Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 9/114 (7%) Query: 40 RNIRPNIILVLTDDQDVE----LGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSI 95 RN RPNI+L++ DD V G+ V + G MC PSR++ Sbjct: 3 RNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAF 62 Query: 96 LTGKY-VHNHNTYTNNENCS----SPSWQAQHESRTFAVYLNSTGYRTAFFGKY 144 LTG+Y + + N N + S TFA L GYRT GK+ Sbjct: 63 LTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKW 116 >gi|71852584 arylsulfatase D isoform a precursor [Homo sapiens] Length = 593 Score = 43.5 bits (101), Expect = 8e-04 Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 15/109 (13%) Query: 297 IYNMLVETGELDNTYIVYTADHGYHI----------GQFGLVK-GKSM-PYEFDIRVPFY 344 + N + + G ++T+ +T+DHG H+ G G+ K GK M +E IRVP Sbjct: 336 VLNAIEDNGLKNSTFTYFTSDHGGHLEARDGHSQLGGWNGIYKGGKGMGGWEGGIRVPGI 395 Query: 345 VRGPNV-EAGCLNPHIVLNIDLAPTILDIAGLDIPAD--MDGKSILKLL 390 P V AG + +D+ PT++ + G ++P D +DG S++ LL Sbjct: 396 FHWPGVLPAGRVIGEPTSLMDVFPTVVQLVGGEVPQDRVIDGHSLVPLL 444 Score = 42.7 bits (99), Expect = 0.001 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 14/113 (12%) Query: 43 RPNIILVLTDDQDV-ELGSMQVMNKTRRI-----MEQGGAHFINAFVTTPMCCPSRSSIL 96 +PNI+L++ DD +LG N T R + + G P+C PSR++ L Sbjct: 40 KPNILLIMADDLGTGDLGCYG--NNTLRTPNIDQLAEEGVRLTQHLAAAPLCTPSRAAFL 97 Query: 97 TGKYVHNHNTYTNNENCSSPSWQA-----QHESRTFAVYLNSTGYRTAFFGKY 144 TG++ +N + W A TFA L GY T GK+ Sbjct: 98 TGRHSFRSGMDASN-GYRALQWNAGSGGLPENETTFARILQQHGYATGLIGKW 149 >gi|71852586 arylsulfatase D isoform b precursor [Homo sapiens] Length = 382 Score = 42.7 bits (99), Expect = 0.001 Identities = 32/113 (28%), Positives = 47/113 (41%), Gaps = 14/113 (12%) Query: 43 RPNIILVLTDDQDV-ELGSMQVMNKTRRI-----MEQGGAHFINAFVTTPMCCPSRSSIL 96 +PNI+L++ DD +LG N T R + + G P+C PSR++ L Sbjct: 40 KPNILLIMADDLGTGDLGCYG--NNTLRTPNIDQLAEEGVRLTQHLAAAPLCTPSRAAFL 97 Query: 97 TGKYVHNHNTYTNNENCSSPSWQA-----QHESRTFAVYLNSTGYRTAFFGKY 144 TG++ +N + W A TFA L GY T GK+ Sbjct: 98 TGRHSFRSGMDASN-GYRALQWNAGSGGLPENETTFARILQQHGYATGLIGKW 149 >gi|157266309 arylsulfatase E precursor [Homo sapiens] Length = 589 Score = 40.4 bits (93), Expect = 0.007 Identities = 37/109 (33%), Positives = 56/109 (51%), Gaps = 15/109 (13%) Query: 297 IYNMLVETGELDNTYIVYTADHGYHI----------GQFGLVKG-KSMP-YEFDIRVPFY 344 I + L G ++T I +T+DHG + G G+ KG K M +E IRVP Sbjct: 333 ILDTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWEGGIRVPGI 392 Query: 345 VRGPNV-EAGCLNPHIVLNIDLAPTILDIAGLDIPAD--MDGKSILKLL 390 R P V AG + +D+ PT++ +AG ++P D +DG+ +L LL Sbjct: 393 FRWPGVLPAGRVIGEPTSLMDVFPTVVRLAGGEVPQDRVIDGQDLLPLL 441 Score = 38.9 bits (89), Expect = 0.021 Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 12/112 (10%) Query: 43 RPNIILVLTDDQDV-ELG-----SMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSIL 96 RPNI+L++ DD + ++G +M+ N R + + G +C PSR++ L Sbjct: 37 RPNILLLMADDLGIGDIGCYGNNTMRTPNIDR--LAEDGVKLTQHISAASLCTPSRAAFL 94 Query: 97 TGKYVHNHNTYTNNE----NCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKY 144 TG+Y ++ + S TFA L GY T GK+ Sbjct: 95 TGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYATGLIGKW 146 >gi|51702222 SPT2, Suppressor of Ty, domain containing 1 [Homo sapiens] Length = 685 Score = 32.3 bits (72), Expect = 2.0 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Query: 631 IDHEIETLQNKIKNLREVRGHLKKKRPEECDCHKISYHTQHKGRLKHRGSSLHPFRKGLQ 690 I+ E E + K++RE+ G+ +KK +E D + K + K SL R G+Q Sbjct: 605 IEDEGEPQEEISKHIREIFGYDRKKYKDESDYALRYMESSWKEQQKEEAKSL---RLGMQ 661 Query: 691 EKDKVWLLREQKRKKKLRKLLKR 713 E + E++ +++ K LKR Sbjct: 662 EDLEEMRREEEEMQRRRAKKLKR 684 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.429 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,484,273 Number of Sequences: 37866 Number of extensions: 1749822 Number of successful extensions: 4618 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 20 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 4509 Number of HSP's gapped (non-prelim): 68 length of query: 870 length of database: 18,247,518 effective HSP length: 111 effective length of query: 759 effective length of database: 14,044,392 effective search space: 10659693528 effective search space used: 10659693528 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.