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Search of human proteins with 239757284
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239757284 PREDICTED: similar to Fc fragment of IgG binding
protein [Homo sapiens]
(593 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 1293 0.0
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 1165 0.0
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 1158 0.0
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 546 e-155
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 331 1e-90
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 297 2e-80
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 297 2e-80
gi|134268640 tectorin alpha precursor [Homo sapiens] 255 7e-68
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 192 6e-49
gi|161019170 mucin 5AC [Homo sapiens] 181 2e-45
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 178 1e-44
gi|116284392 mucin 2 precursor [Homo sapiens] 177 3e-44
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 177 3e-44
gi|134031945 SCO-spondin [Homo sapiens] 166 6e-41
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 160 3e-39
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 160 4e-39
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 160 4e-39
gi|151301154 mucin 6, gastric [Homo sapiens] 151 1e-36
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 147 3e-35
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 147 3e-35
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 147 3e-35
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 147 3e-35
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 147 3e-35
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 147 3e-35
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 142 7e-34
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 142 7e-34
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 142 7e-34
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 127 3e-29
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 121 2e-27
gi|37693519 BMP-binding endothelial regulator precursor protein ... 105 2e-22
>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding
protein [Homo sapiens]
Length = 593
Score = 1293 bits (3346), Expect = 0.0
Identities = 593/593 (100%), Positives = 593/593 (100%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG
Sbjct: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
Query: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 120
DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY
Sbjct: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 120
Query: 121 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 180
QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA
Sbjct: 121 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 180
Query: 181 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 240
GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN
Sbjct: 181 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 240
Query: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG
Sbjct: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
Query: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN
Sbjct: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
Query: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA
Sbjct: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
Query: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG
Sbjct: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
Query: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGLDEGSLSDHKDKIFMCYTSC 593
GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGLDEGSLSDHKDKIFMCYTSC
Sbjct: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGLDEGSLSDHKDKIFMCYTSC 593
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 1165 bits (3014), Expect = 0.0
Identities = 537/573 (93%), Positives = 538/573 (93%), Gaps = 34/573 (5%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG
Sbjct: 1336 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 1395
Query: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 120
DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY
Sbjct: 1396 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 1455
Query: 121 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 180
QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA
Sbjct: 1456 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 1515
Query: 181 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 240
GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN
Sbjct: 1516 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 1575
Query: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK +VCQEHSCKPGQVCQPSGG
Sbjct: 1576 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGG 1635
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
ILSCVTK DPCHGVTCRPQETCKEQGG
Sbjct: 1636 ILSCVTK----------------------------------DPCHGVTCRPQETCKEQGG 1661
Query: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN
Sbjct: 1662 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 1721
Query: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA
Sbjct: 1722 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 1781
Query: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG
Sbjct: 1782 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 1841
Query: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG
Sbjct: 1842 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 1874
Score = 1138 bits (2943), Expect = 0.0
Identities = 527/573 (91%), Positives = 527/573 (91%), Gaps = 34/573 (5%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ MCGLCGNYNG
Sbjct: 3738 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 3797
Query: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 120
DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP CPPGS CIPS KCPPELEKKY
Sbjct: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKY 3857
Query: 121 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 180
QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA
Sbjct: 3858 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 3917
Query: 181 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 240
GGHVEPWR ETFCPMECP NSHYELCADTCSLGCSALSAP QC DGCAEGCQCDSGFLYN
Sbjct: 3918 GGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYN 3977
Query: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCH GKVVVCQEHSCKPGQVCQPSGG
Sbjct: 3978 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGG 4037
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
ILSCVTK DPCHGVTCRPQETCKEQGG
Sbjct: 4038 ILSCVTK----------------------------------DPCHGVTCRPQETCKEQGG 4063
Query: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN
Sbjct: 4064 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 4123
Query: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV QGASKA
Sbjct: 4124 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKA 4183
Query: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG
Sbjct: 4184 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 4243
Query: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG
Sbjct: 4244 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 4276
Score = 1134 bits (2934), Expect = 0.0
Identities = 525/573 (91%), Positives = 526/573 (91%), Gaps = 34/573 (5%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ MCGLCGNYNG
Sbjct: 2537 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 2596
Query: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 120
DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP CPPGSE CIPS +CPPELEKKY
Sbjct: 2597 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKY 2656
Query: 121 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 180
QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA
Sbjct: 2657 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 2716
Query: 181 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 240
GG VEPWR ETFCPMECP NSHYELCADTCSLGCSALSAP QC DGCAEGCQCDSGFLYN
Sbjct: 2717 GGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYN 2776
Query: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
GQACVPIQQCGCYHNG YYEPEQTVLIDNCRQQCTCH GKVVVCQEHSCKPGQVCQPSGG
Sbjct: 2777 GQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGG 2836
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
ILSCV K DPCHGVTCRPQETCKEQGG
Sbjct: 2837 ILSCVNK----------------------------------DPCHGVTCRPQETCKEQGG 2862
Query: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN
Sbjct: 2863 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 2922
Query: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA
Sbjct: 2923 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 2982
Query: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG
Sbjct: 2983 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 3042
Query: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG
Sbjct: 3043 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 3075
Score = 388 bits (996), Expect = e-108
Identities = 217/572 (37%), Positives = 285/572 (49%), Gaps = 78/572 (13%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LP A+GQ++ + G D V+ TDFGL V YD V VP +Y + +CGLCGN+NGDP
Sbjct: 951 LPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDP 1010
Query: 63 KDDFQKPNGSQAGNANEFGNSW-EEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
DD G QA NA FGNSW EE P P CP K + ++ Q
Sbjct: 1011 ADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCP----------KLDSLVAQQLQ 1060
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
+ CG+L+ P GP CH +DPQG ++DC++D CL G LC + Y +ACQAAG
Sbjct: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAG 1120
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
V PWR+E CP+ CPP+SHYE C+ C L C L P C C EGC CD GF +G
Sbjct: 1121 ATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
Query: 242 QACVPIQQCGCYHNGVYYEPEQTVLI-DNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
++C+P+ CGC H G Y+ P QT C C C G +V C+ SC P + CQPSGG
Sbjct: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
L CV TC+ G
Sbjct: 1241 SLGCVAV-------------------------------------------GSSTCQASGD 1257
Query: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
P+Y +FDGR+FDF GTC YVLA T C + GL F V +N
Sbjct: 1258 -----PHYT------------TFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQEN 1297
Query: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
GN VS RV+TV + + + + KV VNGV LPV +A+G+I +Q S
Sbjct: 1298 VAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDV 1356
Query: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P +D PNG+ A + +G
Sbjct: 1357 VIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG 1416
Query: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYE 572
SW D C CP ED + ++
Sbjct: 1417 NSWEEVVPDSPCLPPT--PCPPGSEDCIPSHK 1446
Score = 347 bits (890), Expect = 2e-95
Identities = 206/558 (36%), Positives = 275/558 (49%), Gaps = 94/558 (16%)
Query: 12 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ---- 67
+ A G+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD +
Sbjct: 2168 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGG 2227
Query: 68 KPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCG 127
KP G Q G A G + PCP C PE ++ + + CG
Sbjct: 2228 KPAGWQVGGAQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACG 2267
Query: 128 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPW 187
++S+ GPL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + W
Sbjct: 2268 VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREW 2327
Query: 188 RTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPI 247
R FCP +CP +SHYELC D+C C +LSAP C+ C EGC CD+GF+ +G CVP+
Sbjct: 2328 RRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPV 2387
Query: 248 QQCGCYHNGVYYEPEQTVLI-DNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVT 306
QCGC H+ YY QT C C C G V C+ SC P + C+PSGG L CV
Sbjct: 2388 GQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCV- 2446
Query: 307 KVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLP 366
++ T TC+ G P
Sbjct: 2447 -----AVGST-------------------------------------TCQASGD-----P 2459
Query: 367 NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNP 426
+Y +FDGR+FDF GTC YVLA T C + GL F V +N GN
Sbjct: 2460 HYT------------TFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENVAWGNG 2504
Query: 427 AVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF 486
VS RV+TV + + + + KV VNGV LPV +A+G+I +Q S ++ DF
Sbjct: 2505 RVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDF 2563
Query: 487 GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP 546
GL+V+YD + V VT+P +Y+ +CGLCGN + +P +D PNG+ A + +G SW
Sbjct: 2564 GLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEV 2623
Query: 547 GWDPLCWDECRGSCPTCP 564
D C PTCP
Sbjct: 2624 VPDSPCLPP-----PTCP 2636
Score = 345 bits (885), Expect = 7e-95
Identities = 205/558 (36%), Positives = 274/558 (49%), Gaps = 94/558 (16%)
Query: 12 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ---- 67
+ A G+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD +
Sbjct: 3369 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGG 3428
Query: 68 KPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCG 127
KP G Q G A G + PCP C PE ++ + + CG
Sbjct: 3429 KPAGWQVGGAQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACG 3468
Query: 128 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPW 187
++S+ GPL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + W
Sbjct: 3469 VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREW 3528
Query: 188 RTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPI 247
R FCP +CP +SHYELC D+C C +LSAP C+ C EGC CD+GF+ +G CVP+
Sbjct: 3529 RRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPV 3588
Query: 248 QQCGCYHNGVYYEPEQTVLI-DNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVT 306
QCGC H+ YY QT C C C G V C+ SC P + C+PSGG L CV
Sbjct: 3589 GQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCV- 3647
Query: 307 KVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLP 366
++ T TC+ G P
Sbjct: 3648 -----AVGST-------------------------------------TCQASGD-----P 3660
Query: 367 NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNP 426
+Y +FDG +FDF GTC YVLA T C + GL F V +N GN
Sbjct: 3661 HYT------------TFDGHRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENVAWGNG 3705
Query: 427 AVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF 486
VS RV+TV + + + + KV VNGV LPV +A+G+I +Q S ++ DF
Sbjct: 3706 RVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDF 3764
Query: 487 GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP 546
GL+V+YD + V VT+P +Y+ +CGLCGN + +P +D PNG+ A + +G SW
Sbjct: 3765 GLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEV 3824
Query: 547 GWDPLCWDECRGSCPTCP 564
D C PTCP
Sbjct: 3825 VPDSPCLPP-----PTCP 3837
Score = 331 bits (848), Expect = 1e-90
Identities = 209/598 (34%), Positives = 286/598 (47%), Gaps = 83/598 (13%)
Query: 2 KLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGD 61
+LPV L+ G++R Q G V+E FGL V YD + +++P + Q+CGLCGNYNGD
Sbjct: 558 RLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGD 617
Query: 62 PKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
P DDF P+G+ A +A EF +SW+ + D L C G ++ P+ C P + Y+
Sbjct: 618 PADDFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYE 669
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
+ CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G
Sbjct: 670 GDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELG 729
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG-CAEGCQCDSGFLYN 240
V WR+ CP+ CP NS YELC C C+ +AP C C EGC
Sbjct: 730 ISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC--------- 780
Query: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
C+P G +G P + C C Q PGQ
Sbjct: 781 --VCLP----GFVASGGACVPASS---------CGC------TFQGLQLAPGQ------- 812
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQ------ET 354
+V L Q GA H VTCR + E
Sbjct: 813 ------EVWADELCQRRCTCNGAT--------------------HQVTCRDKQSCPAGER 846
Query: 355 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 414
C Q G C P+ TC GDPHY SFDGR+FDF GTC Y+L G G + L F
Sbjct: 847 CSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLV--GSCGQNA-ALPAF 903
Query: 415 TVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 474
V +N++RG+ VSY R V V A G +++ ++ G+V V+ VL LP ADG++ V
Sbjct: 904 RVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
Query: 475 QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP 534
+ A++ DFGL V+YDWN RV +PSSY A+CGLCGN + +P +D G A
Sbjct: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAA 1023
Query: 535 SIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGLDE-GSLSDHKDKIFMCYT 591
+ +G SW+ P C G CP +Q + +E G L+D K C++
Sbjct: 1024 NALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
Score = 326 bits (835), Expect = 4e-89
Identities = 199/583 (34%), Positives = 290/583 (49%), Gaps = 91/583 (15%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LPV +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P
Sbjct: 4165 LPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 4224
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKY 120
+D PNG+ A + +G SW D C CP CP + ++Y
Sbjct: 4225 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQY 4274
Query: 121 QKEEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
+ FCG LSS TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQA
Sbjct: 4275 EGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQA 4334
Query: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSG 236
AG +E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+G
Sbjct: 4335 AGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG 4394
Query: 237 FLYNGQACVPIQQ-CGCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQ 293
F+ + CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+
Sbjct: 4395 FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGE 4454
Query: 294 VCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQE 353
VC +L +GQ HG C+P
Sbjct: 4455 VC----------------------------GLLPSGQ--------------HG--CQPVS 4470
Query: 354 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 413
T A C WGDPHY + DG +FDFQGTC Y+L+ C G G
Sbjct: 4471 T---------------AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP-CHG-PPLGAEN 4513
Query: 414 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 473
FTVT N++RG+ AVSY R VT+ ++++ K++V+GV ALP + D +
Sbjct: 4514 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHA 4572
Query: 474 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 533
+ ++ GL +++D + V + +P++Y ++CGLCGN +++P +D G A
Sbjct: 4573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 4632
Query: 534 PSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGLD 575
W+ G C + CP+ C ++ E + G D
Sbjct: 4633 --------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPD 4666
Score = 323 bits (829), Expect = 2e-88
Identities = 197/583 (33%), Positives = 289/583 (49%), Gaps = 91/583 (15%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LPV +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P
Sbjct: 2964 LPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 3023
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKY 120
+D PNG+ A + +G SW D C CP CP + ++Y
Sbjct: 3024 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQY 3073
Query: 121 QKEEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
+ FCG L+ TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQA
Sbjct: 3074 EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQA 3133
Query: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSG 236
AG +E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+G
Sbjct: 3134 AGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG 3193
Query: 237 FLYNGQACVPIQQ-CGCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQ 293
F+ + CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+
Sbjct: 3194 FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGE 3253
Query: 294 VCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQE 353
VC +L +GQ HG C+P
Sbjct: 3254 VC----------------------------GLLPSGQ--------------HG--CQPVS 3269
Query: 354 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 413
T A C WGDPHY + DG +FDFQGTC Y+L+ C G G
Sbjct: 3270 T---------------AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP-CHG-PPLGAEN 3312
Query: 414 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 473
FTVT N++RG+ AVSY R VT+ ++++ K++V+GV LP + D +
Sbjct: 3313 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHA 3371
Query: 474 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 533
+ ++ GL +++D + V + +P++Y G++CGLCGN +++P +D G A
Sbjct: 3372 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 3431
Query: 534 PSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGLD 575
W+ G C + CP+ C ++ E + G D
Sbjct: 3432 --------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPD 3465
Score = 322 bits (825), Expect = 6e-88
Identities = 196/583 (33%), Positives = 289/583 (49%), Gaps = 91/583 (15%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LPV +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P
Sbjct: 1763 LPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 1822
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKY 120
+D PNG+ A + +G SW D C CP CP + ++Y
Sbjct: 1823 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQY 1872
Query: 121 QKEEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
+ FCG L+ TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQA
Sbjct: 1873 EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQA 1932
Query: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSG 236
AG +E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+G
Sbjct: 1933 AGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG 1992
Query: 237 FLYNGQACVPIQQ-CGCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQ 293
F+ + CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+
Sbjct: 1993 FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGE 2052
Query: 294 VCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQE 353
VC +L +GQ HG C+P
Sbjct: 2053 VC----------------------------GLLPSGQ--------------HG--CQPVS 2068
Query: 354 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 413
T A C WGDPHY + DG +F+FQGTC Y+L+ C G G
Sbjct: 2069 T---------------AECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP-CHG-PPLGAEN 2111
Query: 414 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 473
FTVT N++RG+ AVSY R VT+ ++++ K++V+GV LP + D +
Sbjct: 2112 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHA 2170
Query: 474 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 533
+ ++ GL +++D + V + +P++Y G++CGLCGN +++P +D G A
Sbjct: 2171 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 2230
Query: 534 PSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGLD 575
W+ G C + CP+ C ++ E + G D
Sbjct: 2231 --------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPD 2264
Score = 315 bits (807), Expect = 7e-86
Identities = 190/568 (33%), Positives = 271/568 (47%), Gaps = 99/568 (17%)
Query: 12 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ---- 67
+ A G+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD +
Sbjct: 4570 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGG 4629
Query: 68 KPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCG 127
KP G Q G A G + PCP C PE ++ + + CG
Sbjct: 4630 KPAGWQVGGAQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACG 4669
Query: 128 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPW 187
++S+ GPL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + W
Sbjct: 4670 VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEW 4729
Query: 188 RTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPI 247
R FCP++CP +SHYELC D+C + C +LSAP C+ C EGC CD+GF+ +G CVP+
Sbjct: 4730 RRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPV 4789
Query: 248 QQCGCYHNGVYYEPEQTVLIDN--CRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCV 305
QCGC H+G Y P V C ++C C GG ++C
Sbjct: 4790 GQCGCLHDG-RYYPLGEVFYPGPECERRCECGP--------------------GGHVTCQ 4828
Query: 306 TKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCL 365
EGAA C P E C+ + G C
Sbjct: 4829 ---------------EGAA------------------------CGPHEECRLEDGVQACH 4849
Query: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGN 425
C G HY + DGR +D G+C+YVLA P G F++ + G+
Sbjct: 4850 ATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHP---KPGDEDFSIVLEKNAAGD 4906
Query: 426 PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVAD 485
++ + V G +S+ + + +V V+G ALPV+V GR+ VT +L
Sbjct: 4907 -----LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVAV--GRVRVTAEGRNMVLQTT 4957
Query: 486 FGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRA 545
GL++ +D + + +++PS + G +CGLCGN + N ++D V PNG+ A S+ +G +WRA
Sbjct: 4958 KGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRA 5017
Query: 546 PGWDPLCWDEC-RGSCPTCPEDRLEQYE 572
PG C + C CP C + YE
Sbjct: 5018 PGSSKGCGEGCGPQGCPVCLAEETAPYE 5045
Score = 254 bits (649), Expect = 2e-67
Identities = 114/303 (37%), Positives = 173/303 (57%), Gaps = 11/303 (3%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LPV + G++R + G ++V++T GLR+ +D ++ +++P + ++CGLCGN+NG+
Sbjct: 4936 LPVAV--GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNW 4993
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPC-PPGSEDCIPSHKCPPELEKKYQ 121
DDF PNGS A + FG +W C C P G C+ P Y+
Sbjct: 4994 SDDFVLPNGSAASSVETFGAAWRAPGSSKGC--GEGCGPQGCPVCLAEETAP------YE 5045
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ AY +ACQAAG
Sbjct: 5046 SNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAG 5105
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
V+PWRT++FCP+ CP +SHY +C TC C+ALS C C EGC+CD FL +
Sbjct: 5106 VAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ 5165
Query: 242 QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGI 301
C+P+Q CGC HNG Y ++L +C ++C+C + + CQ C PG+VC+
Sbjct: 5166 GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 5225
Query: 302 LSC 304
+C
Sbjct: 5226 RNC 5228
Score = 187 bits (474), Expect = 3e-47
Identities = 93/238 (39%), Positives = 142/238 (59%), Gaps = 5/238 (2%)
Query: 338 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 395
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 436 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 495
Query: 396 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 455
Y + C T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 496 YTMVEL-CSEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 552
Query: 456 NGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 515
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 553 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 612
Query: 516 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 613 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEG 670
Score = 32.0 bits (71), Expect = 1.6
Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 7 LANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDF 66
LA+ + + GS +++ G++V V V V ++ ++CG CGN++GD +D+
Sbjct: 5325 LASVSVSRTPDGS-LLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 1158 bits (2996), Expect = 0.0
Identities = 536/575 (93%), Positives = 537/575 (93%), Gaps = 36/575 (6%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG
Sbjct: 1336 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 1395
Query: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 120
DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY
Sbjct: 1396 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 1455
Query: 121 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 180
QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA
Sbjct: 1456 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 1515
Query: 181 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 240
GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN
Sbjct: 1516 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 1575
Query: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK +VCQEHSCKPGQVCQPSGG
Sbjct: 1576 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGG 1635
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
ILSCVTK DPCHGVTCRPQETCKEQGG
Sbjct: 1636 ILSCVTK----------------------------------DPCHGVTCRPQETCKEQGG 1661
Query: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN
Sbjct: 1662 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 1721
Query: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV--NGVLTALPVSVADGRISVTQGAS 478
QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV NGVLTALPVSVADGRISV QGAS
Sbjct: 1722 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGAS 1781
Query: 479 KALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPI 538
KALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPI
Sbjct: 1782 KALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPI 1841
Query: 539 WGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
WGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG
Sbjct: 1842 WGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 1876
Score = 388 bits (996), Expect = e-108
Identities = 217/572 (37%), Positives = 285/572 (49%), Gaps = 78/572 (13%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LP A+GQ++ + G D V+ TDFGL V YD V VP +Y + +CGLCGN+NGDP
Sbjct: 951 LPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDP 1010
Query: 63 KDDFQKPNGSQAGNANEFGNSW-EEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
DD G QA NA FGNSW EE P P CP K + ++ Q
Sbjct: 1011 ADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCP----------KLDSLVAQQLQ 1060
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
+ CG+L+ P GP CH +DPQG ++DC++D CL G LC + Y +ACQAAG
Sbjct: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAG 1120
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
V PWR+E CP+ CPP+SHYE C+ C L C L P C C EGC CD GF +G
Sbjct: 1121 ATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
Query: 242 QACVPIQQCGCYHNGVYYEPEQTVLI-DNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
++C+P+ CGC H G Y+ P QT C C C G +V C+ SC P + CQPSGG
Sbjct: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
L CV TC+ G
Sbjct: 1241 SLGCVAV-------------------------------------------GSSTCQASGD 1257
Query: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
P+Y +FDGR+FDF GTC YVLA T C + GL F V +N
Sbjct: 1258 -----PHYT------------TFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQEN 1297
Query: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
GN VS RV+TV + + + + KV VNGV LPV +A+G+I +Q S
Sbjct: 1298 VAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDV 1356
Query: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P +D PNG+ A + +G
Sbjct: 1357 VIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG 1416
Query: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYE 572
SW D C CP ED + ++
Sbjct: 1417 NSWEEVVPDSPCLPPT--PCPPGSEDCIPSHK 1446
Score = 331 bits (848), Expect = 1e-90
Identities = 209/598 (34%), Positives = 286/598 (47%), Gaps = 83/598 (13%)
Query: 2 KLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGD 61
+LPV L+ G++R Q G V+E FGL V YD + +++P + Q+CGLCGNYNGD
Sbjct: 558 RLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGD 617
Query: 62 PKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
P DDF P+G+ A +A EF +SW+ + D L C G ++ P+ C P + Y+
Sbjct: 618 PADDFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYE 669
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
+ CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G
Sbjct: 670 GDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELG 729
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG-CAEGCQCDSGFLYN 240
V WR+ CP+ CP NS YELC C C+ +AP C C EGC
Sbjct: 730 ISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC--------- 780
Query: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
C+P G +G P + C C Q PGQ
Sbjct: 781 --VCLP----GFVASGGACVPASS---------CGC------TFQGLQLAPGQ------- 812
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQ------ET 354
+V L Q GA H VTCR + E
Sbjct: 813 ------EVWADELCQRRCTCNGAT--------------------HQVTCRDKQSCPAGER 846
Query: 355 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 414
C Q G C P+ TC GDPHY SFDGR+FDF GTC Y+L G G + L F
Sbjct: 847 CSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLV--GSCGQNA-ALPAF 903
Query: 415 TVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 474
V +N++RG+ VSY R V V A G +++ ++ G+V V+ VL LP ADG++ V
Sbjct: 904 RVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
Query: 475 QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP 534
+ A++ DFGL V+YDWN RV +PSSY A+CGLCGN + +P +D G A
Sbjct: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAA 1023
Query: 535 SIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGLDE-GSLSDHKDKIFMCYT 591
+ +G SW+ P C G CP +Q + +E G L+D K C++
Sbjct: 1024 NALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
Score = 325 bits (832), Expect = 9e-89
Identities = 198/583 (33%), Positives = 290/583 (49%), Gaps = 91/583 (15%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LPV +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P
Sbjct: 1765 LPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 1824
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKY 120
+D PNG+ A + +G SW D C CP CP + ++Y
Sbjct: 1825 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQY 1874
Query: 121 QKEEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
+ FCG L+S TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQA
Sbjct: 1875 EGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQA 1934
Query: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSG 236
AG +E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+G
Sbjct: 1935 AGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG 1994
Query: 237 FLYNGQACVPIQQ-CGCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQ 293
F+ + CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+
Sbjct: 1995 FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGE 2054
Query: 294 VCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQE 353
VC +L +GQ HG C+P
Sbjct: 2055 VC----------------------------GLLPSGQ--------------HG--CQPVS 2070
Query: 354 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 413
T A C WGDPHY + DG +FDFQGTC Y+L+ C G G
Sbjct: 2071 T---------------AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP-CHG-PPLGAEN 2113
Query: 414 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 473
FTVT N++RG+ AVSY R VT+ ++++ K++V+GV ALP + D +
Sbjct: 2114 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHA 2172
Query: 474 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 533
+ ++ GL +++D + V + +P++Y ++CGLCGN +++P +D G A
Sbjct: 2173 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 2232
Query: 534 PSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGLD 575
W+ G C + CP+ C ++ E + G D
Sbjct: 2233 --------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPD 2266
Score = 315 bits (807), Expect = 7e-86
Identities = 190/568 (33%), Positives = 271/568 (47%), Gaps = 99/568 (17%)
Query: 12 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ---- 67
+ A G+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD +
Sbjct: 2170 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGG 2229
Query: 68 KPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCG 127
KP G Q G A G + PCP C PE ++ + + CG
Sbjct: 2230 KPAGWQVGGAQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACG 2269
Query: 128 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPW 187
++S+ GPL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + W
Sbjct: 2270 VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEW 2329
Query: 188 RTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPI 247
R FCP++CP +SHYELC D+C + C +LSAP C+ C EGC CD+GF+ +G CVP+
Sbjct: 2330 RRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPV 2389
Query: 248 QQCGCYHNGVYYEPEQTVLIDN--CRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCV 305
QCGC H+G Y P V C ++C C GG ++C
Sbjct: 2390 GQCGCLHDG-RYYPLGEVFYPGPECERRCECGP--------------------GGHVTCQ 2428
Query: 306 TKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCL 365
EGAA C P E C+ + G C
Sbjct: 2429 ---------------EGAA------------------------CGPHEECRLEDGVQACH 2449
Query: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGN 425
C G HY + DGR +D G+C+YVLA P G F++ + G+
Sbjct: 2450 ATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHP---KPGDEDFSIVLEKNAAGD 2506
Query: 426 PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVAD 485
++ + V G +S+ + + +V V+G ALPV+V GR+ VT +L
Sbjct: 2507 -----LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVAV--GRVRVTAEGRNMVLQTT 2557
Query: 486 FGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRA 545
GL++ +D + + +++PS + G +CGLCGN + N ++D V PNG+ A S+ +G +WRA
Sbjct: 2558 KGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRA 2617
Query: 546 PGWDPLCWDEC-RGSCPTCPEDRLEQYE 572
PG C + C CP C + YE
Sbjct: 2618 PGSSKGCGEGCGPQGCPVCLAEETAPYE 2645
Score = 254 bits (649), Expect = 2e-67
Identities = 114/303 (37%), Positives = 173/303 (57%), Gaps = 11/303 (3%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LPV + G++R + G ++V++T GLR+ +D ++ +++P + ++CGLCGN+NG+
Sbjct: 2536 LPVAV--GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNW 2593
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPC-PPGSEDCIPSHKCPPELEKKYQ 121
DDF PNGS A + FG +W C C P G C+ P Y+
Sbjct: 2594 SDDFVLPNGSAASSVETFGAAWRAPGSSKGC--GEGCGPQGCPVCLAEETAP------YE 2645
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ AY +ACQAAG
Sbjct: 2646 SNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAG 2705
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
V+PWRT++FCP+ CP +SHY +C TC C+ALS C C EGC+CD FL +
Sbjct: 2706 VAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ 2765
Query: 242 QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGI 301
C+P+Q CGC HNG Y ++L +C ++C+C + + CQ C PG+VC+
Sbjct: 2766 GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 2825
Query: 302 LSC 304
+C
Sbjct: 2826 RNC 2828
Score = 187 bits (474), Expect = 3e-47
Identities = 93/238 (39%), Positives = 142/238 (59%), Gaps = 5/238 (2%)
Query: 338 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 395
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 436 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 495
Query: 396 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 455
Y + C T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 496 YTMVEL-CSEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 552
Query: 456 NGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 515
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 553 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 612
Query: 516 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 613 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEG 670
Score = 32.0 bits (71), Expect = 1.6
Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 7 LANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDF 66
LA+ + + GS +++ G++V V V V ++ ++CG CGN++GD +D+
Sbjct: 2925 LASVSVSRTPDGS-LLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 2983
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding
protein [Homo sapiens]
Length = 1403
Score = 546 bits (1408), Expect = e-155
Identities = 251/256 (98%), Positives = 254/256 (99%)
Query: 318 VDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD 377
VD+EGAA+LYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD
Sbjct: 21 VDMEGAAMLYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD 80
Query: 378 PHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 437
PHYHSFDGRKFDFQGTCNYVLATTGC GVSTQGLTPFTVTTKN+NRGNPAVSYVRVVTVA
Sbjct: 81 PHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVA 140
Query: 438 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWR 497
ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV QGASKALLVADFGLQVSYDWNWR
Sbjct: 141 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR 200
Query: 498 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 557
VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR
Sbjct: 201 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 260
Query: 558 GSCPTCPEDRLEQYEG 573
GSCPTCPEDRLEQYEG
Sbjct: 261 GSCPTCPEDRLEQYEG 276
Score = 322 bits (826), Expect = 5e-88
Identities = 197/583 (33%), Positives = 289/583 (49%), Gaps = 91/583 (15%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LPV +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P
Sbjct: 165 LPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 224
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKY 120
+D PNG+ A + +G SW D C CP CP + ++Y
Sbjct: 225 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQY 274
Query: 121 QKEEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
+ FCG L+ TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQA
Sbjct: 275 EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQA 334
Query: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSG 236
AG +E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+G
Sbjct: 335 AGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG 394
Query: 237 FLYNGQACVPIQQ-CGCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQ 293
F+ + CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+
Sbjct: 395 FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGE 454
Query: 294 VCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQE 353
VC +L +GQ HG C+P
Sbjct: 455 VC----------------------------GLLPSGQ--------------HG--CQPVS 470
Query: 354 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 413
T A C WGDPHY + DG +FDFQGTC Y+L+ C G G
Sbjct: 471 T---------------AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP-CHG-PPLGAEN 513
Query: 414 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 473
FTVT N++RG+ AVSY R VT+ ++++ K++V+GV ALP + D +
Sbjct: 514 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHA 572
Query: 474 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 533
+ ++ GL +++D + V + +P++Y ++CGLCGN +++P +D G A
Sbjct: 573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 632
Query: 534 PSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGLD 575
W+ G C + CP+ C ++ E + G D
Sbjct: 633 --------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPD 666
Score = 313 bits (803), Expect = 2e-85
Identities = 189/568 (33%), Positives = 270/568 (47%), Gaps = 99/568 (17%)
Query: 12 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ---- 67
+ A G+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD +
Sbjct: 570 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGG 629
Query: 68 KPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCG 127
KP G Q G A G + PCP C PE ++ + + CG
Sbjct: 630 KPAGWQVGGAQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACG 669
Query: 128 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPW 187
++S+ GPL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + W
Sbjct: 670 VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEW 729
Query: 188 RTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPI 247
R FCP++CP +SHYELC D+C + C +LSAP C+ C EGC CD+GF+ +G CVP+
Sbjct: 730 RRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPV 789
Query: 248 QQCGCYHNGVYYEPEQTVLIDN--CRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCV 305
QCGC H+G Y P V C ++C C GG ++C
Sbjct: 790 GQCGCLHDG-RYYPLGEVFYPGPECERRCECGP--------------------GGHVTCQ 828
Query: 306 TKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCL 365
EGAA C P E C+ + G C
Sbjct: 829 ---------------EGAA------------------------CGPHEECRLEDGVQACH 849
Query: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGN 425
C G HY + DGR +D G+C+YVLA P G F++ + G+
Sbjct: 850 ATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHP---KPGDEDFSIVLEKNAAGD 906
Query: 426 PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVAD 485
++ + V G +S+ + + +V V+G ALPV+V GR+ VT +L
Sbjct: 907 -----LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVAV--GRVRVTAEGRNMVLQTT 957
Query: 486 FGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRA 545
GL++ +D + + +++PS + G +CGLCGN + N ++D V PNG+ A S+ +G +WR
Sbjct: 958 KGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRV 1017
Query: 546 PGWDPLCWDEC-RGSCPTCPEDRLEQYE 572
PG C + C CP C + YE
Sbjct: 1018 PGSSKGCGEGCGPQGCPVCLAEETAPYE 1045
Score = 255 bits (652), Expect = 7e-68
Identities = 116/303 (38%), Positives = 175/303 (57%), Gaps = 11/303 (3%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LPV + G++R + G ++V++T GLR+ +D ++ +++P + ++CGLCGN+NG+
Sbjct: 936 LPVAV--GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNW 993
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPC-PPGSEDCIPSHKCPPELEKKYQ 121
DDF PNGS A + FG +W VP S C P G C+ P Y+
Sbjct: 994 SDDFVLPNGSAASSVETFGAAWR--VPGSSKGCGEGCGPQGCPVCLAEETAP------YE 1045
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ AY +ACQAAG
Sbjct: 1046 SNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAG 1105
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
V+PWRT++FCP+ CP +SHY +C TC C+ALS C C EGC+CD FL +
Sbjct: 1106 VAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ 1165
Query: 242 QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGI 301
C+P+Q CGC HNG Y ++L +C ++C+C + + CQ C PG+VC+
Sbjct: 1166 GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 1225
Query: 302 LSC 304
+C
Sbjct: 1226 RNC 1228
Score = 32.0 bits (71), Expect = 1.6
Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 7 LANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDF 66
LA+ + + GS +++ G++V V V V ++ ++CG CGN++GD +D+
Sbjct: 1325 LASVSVSRTPDGS-LLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 1383
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 331 bits (848), Expect = 1e-90
Identities = 209/598 (34%), Positives = 286/598 (47%), Gaps = 83/598 (13%)
Query: 2 KLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGD 61
+LPV L+ G++R Q G V+E FGL V YD + +++P + Q+CGLCGNYNGD
Sbjct: 619 RLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGD 678
Query: 62 PKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
P DDF P+G+ A +A EF +SW+ + D L C G ++ P+ C P + Y+
Sbjct: 679 PADDFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYE 730
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
+ CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G
Sbjct: 731 GDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELG 790
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG-CAEGCQCDSGFLYN 240
V WR+ CP+ CP NS YELC C C+ +AP C C EGC
Sbjct: 791 ISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC--------- 841
Query: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
C+P G +G P + C C Q PGQ
Sbjct: 842 --VCLP----GFVASGGACVPASS---------CGC------TFQGLQLAPGQ------- 873
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQ------ET 354
+V L Q GA H VTCR + E
Sbjct: 874 ------EVWADELCQRRCTCNGAT--------------------HQVTCRDKQSCPAGER 907
Query: 355 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 414
C Q G C P+ TC GDPHY SFDGR+FDF GTC Y+L G G + L F
Sbjct: 908 CSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLV--GSCGQNA-ALPAF 964
Query: 415 TVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 474
V +N++RG+ VSY R V V A G +++ ++ G+V V+ VL LP ADG++ V
Sbjct: 965 RVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 1024
Query: 475 QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP 534
+ A++ DFGL V+YDWN RV +PSSY A+CGLCGN + +P +D G A
Sbjct: 1025 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAA 1084
Query: 535 SIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGLDE-GSLSDHKDKIFMCYT 591
+ +G SW+ P C G CP +Q + +E G L+D K C++
Sbjct: 1085 NALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1141
Score = 313 bits (801), Expect = 4e-85
Identities = 170/436 (38%), Positives = 212/436 (48%), Gaps = 75/436 (17%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LP A+GQ++ + G D V+ TDFGL V YD V VP +Y + +CGLCGN+NGDP
Sbjct: 1012 LPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDP 1071
Query: 63 KDDFQKPNGSQAGNANEFGNSW-EEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
DD G QA NA FGNSW EE P P CP K + ++ Q
Sbjct: 1072 ADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCP----------KLDSLVAQQLQ 1121
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
+ CG+L+ P GP CH +DPQG ++DC++D CL G LC + Y +ACQAAG
Sbjct: 1122 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAG 1181
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
V PWR+E CP+ CPP+SHYE C+ C L C L P C C EGC CD GF +G
Sbjct: 1182 ATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1241
Query: 242 QACVPIQQCGCYHNGVYYEPEQTVLI-DNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
++C+P+ CGC H G Y+ P QT C C C G +V C+ SC P + CQPSGG
Sbjct: 1242 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1301
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
L CV TC+ G
Sbjct: 1302 SLGCVAV-------------------------------------------GSSTCQASGD 1318
Query: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
P+Y +FDGR+FDF GTC YVLA T C + GL F V +N
Sbjct: 1319 -----PHYT------------TFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQEN 1358
Query: 421 QNRGNPAVSYVRVVTV 436
GN VS RV+TV
Sbjct: 1359 VAWGNGRVSVTRVITV 1374
Score = 187 bits (474), Expect = 3e-47
Identities = 93/238 (39%), Positives = 142/238 (59%), Gaps = 5/238 (2%)
Query: 338 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 395
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 497 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 556
Query: 396 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 455
Y + C T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 557 YTMVEL-CSEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 613
Query: 456 NGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 515
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 614 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 673
Query: 516 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 674 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEG 731
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 297 bits (760), Expect = 2e-80
Identities = 182/547 (33%), Positives = 254/547 (46%), Gaps = 77/547 (14%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LP + + G + G V ++T+FGLRV +D + VTV Y ++CGLCGNY+G+
Sbjct: 1240 LPAIPSKGVFLGAS-GRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNS 1298
Query: 63 KDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
+D K +GS AG+ E GNSW+ + D C + S C L+
Sbjct: 1299 DNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ--------KYQVVNSPSCDSSLQSSMS 1350
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
FCG L GP +C V C+ D+C G +LC+++ + CQ AG
Sbjct: 1351 GPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAG 1410
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
V+PWR FCPM CPPNS Y LCA C C + + C D C E C+C+ GF+ +G
Sbjct: 1411 HAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSG 1470
Query: 242 QACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
C+P QCGC H G Y++ + C++ C C + + CQ C+ + C G
Sbjct: 1471 LECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDG 1530
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
I C +GAA TC G
Sbjct: 1531 IYGC--------------HAQGAA-----------------------------TCTASG- 1546
Query: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
DPHY +FDG F GTC YVL P S + F V+ N
Sbjct: 1547 ----------------DPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATN 1587
Query: 421 QNRGN-PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASK 479
+NRG VSY++ V V +IS+ + KV +NG ALPV +A GR+++ ++
Sbjct: 1588 ENRGGILEVSYIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNL 1645
Query: 480 ALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIW 539
LL +FGLQV YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA
Sbjct: 1646 VLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQL 1705
Query: 540 GGSWRAP 546
G +W+ P
Sbjct: 1706 GAAWKLP 1712
Score = 266 bits (679), Expect = 5e-71
Identities = 162/558 (29%), Positives = 249/558 (44%), Gaps = 86/558 (15%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LPV LA G++ + V++ T+FGL+V YD + V VTVP +Y Q+CGLCGNYN +
Sbjct: 1628 LPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNS 1687
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQK 122
DD +P+ AG++ + G +W+ +P+S PG C P ++
Sbjct: 1688 LDDNLRPDRKLAGDSMQLGAAWK--LPES-------SEPG---CFLVGGKPSSCQENSMA 1735
Query: 123 EEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
+ + C +L +P GP S CH++V PQ C+ C G+ + LC ++ AY S C A
Sbjct: 1736 DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC-A 1794
Query: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--CAEGCQCDSGF 237
G WR TFCPM CPP S Y C+ C CS+++ P C CAE C+C G
Sbjct: 1795 QAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGH 1854
Query: 238 LYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVC 295
+ +G +CVP+ QCGC Y P E+ + C + CTC + C + +CKP Q+C
Sbjct: 1855 ILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQIC 1914
Query: 296 QPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETC 355
G+L C
Sbjct: 1915 WALDGLLRC--------------------------------------------------- 1923
Query: 356 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 415
G GVC L G+ HY SFDG C VL P ++ L F
Sbjct: 1924 -RASGVGVC--------QLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFK 1971
Query: 416 VTTKNQ-NRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 474
++ K++ G + V + +++ K +V +N LP +SV
Sbjct: 1972 ISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVK 2029
Query: 475 QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP 534
+ +++ G+QV +D N +++ +P++Y+G VCG+CGN + ++ + P+ +A
Sbjct: 2030 SSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVAN 2089
Query: 535 SIPIWGGSWRAPGWDPLC 552
S + SW+ DP C
Sbjct: 2090 SDSEFVNSWKDKDIDPSC 2107
Score = 200 bits (509), Expect = 3e-51
Identities = 148/541 (27%), Positives = 224/541 (41%), Gaps = 82/541 (15%)
Query: 22 VIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG 81
++ G++V +D + + + +P YY ++CG+CGN+N + +D+ P+ A + +EF
Sbjct: 2036 IVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFV 2095
Query: 82 NSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC-PPELEKKYQKEEFCGLLSSPTGPLS 137
NSW++ D C L P + PS C +L + +K E L +P +
Sbjct: 2096 NSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVW--A 2151
Query: 138 SCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
C +D L DC LC GG LC + A+ + CQ+ G WR +FCP+EC
Sbjct: 2152 QCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLEC 2211
Query: 198 PPNSHYELCADTCSLGCSALSAPPQCQ-----DGCAEGCQCDSGFLYNGQACVPIQQCGC 252
P S Y C +CS C L +C+ CAEGC C G++ + CVP QCG
Sbjct: 2212 PAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCG- 2268
Query: 253 YHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRS 312
C+ H G + + G+ SG CV
Sbjct: 2269 -----------------CKD---AHGGSIPL--------GKSWVSSGCTEKCVCT----- 2295
Query: 313 LAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCK--EQGGQGVCLPNYEA 370
G AI C C C+ C+ +
Sbjct: 2296 ---------GGAI-----------------QCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329
Query: 371 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSY 430
C ++GDP Y +FDG + QG YVL T V +G+ P V +N+ + +
Sbjct: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIF 2387
Query: 431 VRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQV 490
++ V G + + ++ VN A+P + + VT + LV DF L V
Sbjct: 2388 LQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVV 2444
Query: 491 SYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 550
S+ ++LPS Y G V GLCGN D+N ND + P+G L ++ +G SW D
Sbjct: 2445 SFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDA 2504
Query: 551 L 551
L
Sbjct: 2505 L 2505
Score = 151 bits (382), Expect = 1e-36
Identities = 112/352 (31%), Positives = 149/352 (42%), Gaps = 78/352 (22%)
Query: 197 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 256
CPPN+ YE CA C C S P C C EGC C+ GFL++ C+ C C++N
Sbjct: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 257 VYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHS-CKPGQVCQPSGGILSCVTKVTLRSLAQ 315
YYEP N C EH C PG +
Sbjct: 1100 DYYEPGAEWFSPN--------------CTEHCRCWPGSRVE------------------- 1126
Query: 316 TGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNY-EATCWL 374
C C C+ + GQ C P ATC +
Sbjct: 1127 ----------------------------CQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158
Query: 375 WGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVV 434
+GDPHY +FDGR F F G C Y+LA C G ST F VT KN+ +G VS + V
Sbjct: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDPF--FRVTAKNEEQGQEGVSCLSKV 1214
Query: 435 TVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKAL--LVADFGLQVSY 492
V + +++ K + V G LP + G V GAS L +FGL+V +
Sbjct: 1215 YVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKG---VFLGASGRFVELQTEFGLRVRW 1269
Query: 493 DWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
D + ++ VT+ S+Y G +CGLCGN D N +ND + +G+ A G SW+
Sbjct: 1270 DGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQ 1321
Score = 119 bits (297), Expect = 1e-26
Identities = 83/304 (27%), Positives = 130/304 (42%), Gaps = 45/304 (14%)
Query: 9 NGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQK 68
N +R + G + + TDF L V++ +++P Y + GLCGNY+ + K+D
Sbjct: 2422 NEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMML 2481
Query: 69 PNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPP---------GSEDCIPSHKCPPELEKK 119
P+G+ N N FGNSWE D+ P P G + +C PE +
Sbjct: 2482 PSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLA 2540
Query: 120 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
+ C +L+ P GP ++CH+ V P+ + C+ DLC CQ
Sbjct: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQ-------DPREQEELRCQV 2593
Query: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQ--CDSGF 237
GH R H DT S L CQ G G +
Sbjct: 2594 LSGHGVSSR------------YHISELYDTLP---SIL-----CQPGRPRGLRGPLRGRL 2633
Query: 238 LYNGQACV------PIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKP 291
+ + C+ P+ CGC NG+YY+ + L ++C Q+CTC + ++++C+ SC+
Sbjct: 2634 RQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSCRA 2693
Query: 292 GQVC 295
G+VC
Sbjct: 2694 GEVC 2697
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 297 bits (760), Expect = 2e-80
Identities = 182/547 (33%), Positives = 254/547 (46%), Gaps = 77/547 (14%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LP + + G + G V ++T+FGLRV +D + VTV Y ++CGLCGNY+G+
Sbjct: 1240 LPAIPSKGVFLGAS-GRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNS 1298
Query: 63 KDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
+D K +GS AG+ E GNSW+ + D C + S C L+
Sbjct: 1299 DNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQ--------KYQVVNSPSCDSSLQSSMS 1350
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
FCG L GP +C V C+ D+C G +LC+++ + CQ AG
Sbjct: 1351 GPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAG 1410
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
V+PWR FCPM CPPNS Y LCA C C + + C D C E C+C+ GF+ +G
Sbjct: 1411 HAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSG 1470
Query: 242 QACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
C+P QCGC H G Y++ + C++ C C + + CQ C+ + C G
Sbjct: 1471 LECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDG 1530
Query: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
I C +GAA TC G
Sbjct: 1531 IYGC--------------HAQGAA-----------------------------TCTASG- 1546
Query: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
DPHY +FDG F GTC YVL P S + F V+ N
Sbjct: 1547 ----------------DPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATN 1587
Query: 421 QNRGN-PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASK 479
+NRG VSY++ V V +IS+ + KV +NG ALPV +A GR+++ ++
Sbjct: 1588 ENRGGILEVSYIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNL 1645
Query: 480 ALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIW 539
LL +FGLQV YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA
Sbjct: 1646 VLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQL 1705
Query: 540 GGSWRAP 546
G +W+ P
Sbjct: 1706 GAAWKLP 1712
Score = 266 bits (679), Expect = 5e-71
Identities = 162/558 (29%), Positives = 249/558 (44%), Gaps = 86/558 (15%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LPV LA G++ + V++ T+FGL+V YD + V VTVP +Y Q+CGLCGNYN +
Sbjct: 1628 LPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNS 1687
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQK 122
DD +P+ AG++ + G +W+ +P+S PG C P ++
Sbjct: 1688 LDDNLRPDRKLAGDSMQLGAAWK--LPES-------SEPG---CFLVGGKPSSCQENSMA 1735
Query: 123 EEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
+ + C +L +P GP S CH++V PQ C+ C G+ + LC ++ AY S C A
Sbjct: 1736 DAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC-A 1794
Query: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--CAEGCQCDSGF 237
G WR TFCPM CPP S Y C+ C CS+++ P C CAE C+C G
Sbjct: 1795 QAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGH 1854
Query: 238 LYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVC 295
+ +G +CVP+ QCGC Y P E+ + C + CTC + C + +CKP Q+C
Sbjct: 1855 ILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQIC 1914
Query: 296 QPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETC 355
G+L C
Sbjct: 1915 WALDGLLRC--------------------------------------------------- 1923
Query: 356 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 415
G GVC L G+ HY SFDG C VL P ++ L F
Sbjct: 1924 -RASGVGVC--------QLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFK 1971
Query: 416 VTTKNQ-NRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 474
++ K++ G + V + +++ K +V +N LP +SV
Sbjct: 1972 ISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVK 2029
Query: 475 QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP 534
+ +++ G+QV +D N +++ +P++Y+G VCG+CGN + ++ + P+ +A
Sbjct: 2030 SSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVAN 2089
Query: 535 SIPIWGGSWRAPGWDPLC 552
S + SW+ DP C
Sbjct: 2090 SDSEFVNSWKDKDIDPSC 2107
Score = 200 bits (509), Expect = 3e-51
Identities = 148/541 (27%), Positives = 224/541 (41%), Gaps = 82/541 (15%)
Query: 22 VIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG 81
++ G++V +D + + + +P YY ++CG+CGN+N + +D+ P+ A + +EF
Sbjct: 2036 IVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFV 2095
Query: 82 NSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC-PPELEKKYQKEEFCGLLSSPTGPLS 137
NSW++ D C L P + PS C +L + +K E L +P +
Sbjct: 2096 NSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVW--A 2151
Query: 138 SCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
C +D L DC LC GG LC + A+ + CQ+ G WR +FCP+EC
Sbjct: 2152 QCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLEC 2211
Query: 198 PPNSHYELCADTCSLGCSALSAPPQCQ-----DGCAEGCQCDSGFLYNGQACVPIQQCGC 252
P S Y C +CS C L +C+ CAEGC C G++ + CVP QCG
Sbjct: 2212 PAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCG- 2268
Query: 253 YHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRS 312
C+ H G + + G+ SG CV
Sbjct: 2269 -----------------CKD---AHGGSIPL--------GKSWVSSGCTEKCVCT----- 2295
Query: 313 LAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCK--EQGGQGVCLPNYEA 370
G AI C C C+ C+ +
Sbjct: 2296 ---------GGAI-----------------QCGDFRCPSGSHCQLTSDNSNSNCVSDKSE 2329
Query: 371 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSY 430
C ++GDP Y +FDG + QG YVL T V +G+ P V +N+ + +
Sbjct: 2330 QCSVYGDPRYLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIF 2387
Query: 431 VRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQV 490
++ V G + + ++ VN A+P + + VT + LV DF L V
Sbjct: 2388 LQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVV 2444
Query: 491 SYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 550
S+ ++LPS Y G V GLCGN D+N ND + P+G L ++ +G SW D
Sbjct: 2445 SFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDA 2504
Query: 551 L 551
L
Sbjct: 2505 L 2505
Score = 151 bits (382), Expect = 1e-36
Identities = 112/352 (31%), Positives = 149/352 (42%), Gaps = 78/352 (22%)
Query: 197 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 256
CPPN+ YE CA C C S P C C EGC C+ GFL++ C+ C C++N
Sbjct: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 257 VYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHS-CKPGQVCQPSGGILSCVTKVTLRSLAQ 315
YYEP N C EH C PG +
Sbjct: 1100 DYYEPGAEWFSPN--------------CTEHCRCWPGSRVE------------------- 1126
Query: 316 TGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNY-EATCWL 374
C C C+ + GQ C P ATC +
Sbjct: 1127 ----------------------------CQISQCGTHTVCQLKNGQYGCHPYAGTATCLV 1158
Query: 375 WGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVV 434
+GDPHY +FDGR F F G C Y+LA C G ST F VT KN+ +G VS + V
Sbjct: 1159 YGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDPF--FRVTAKNEEQGQEGVSCLSKV 1214
Query: 435 TVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKAL--LVADFGLQVSY 492
V + +++ K + V G LP + G V GAS L +FGL+V +
Sbjct: 1215 YVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKG---VFLGASGRFVELQTEFGLRVRW 1269
Query: 493 DWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
D + ++ VT+ S+Y G +CGLCGN D N +ND + +G+ A G SW+
Sbjct: 1270 DGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQ 1321
Score = 104 bits (259), Expect = 3e-22
Identities = 70/250 (28%), Positives = 107/250 (42%), Gaps = 31/250 (12%)
Query: 9 NGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQK 68
N +R + G + + TDF L V++ +++P Y + GLCGNY+ + K+D
Sbjct: 2422 NEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMML 2481
Query: 69 PNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPP---------GSEDCIPSHKCPPELEKK 119
P+G+ N N FGNSWE D+ P P G + +C PE +
Sbjct: 2482 PSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPE-QLA 2540
Query: 120 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG---NLSILCSNIHAYVSA 176
+ C +L+ P GP ++CH+ V P+ + C+ DLC + C + Y
Sbjct: 2541 SNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAIL 2600
Query: 177 CQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD-GCAEGCQCDS 235
CQ AG + WR T C C N C + QC++ G C+C+
Sbjct: 2601 CQEAGAALAGWRDRTLCESPCLQNP----CQN-----------DGQCREQGATFTCECEV 2645
Query: 236 GFLYNGQACV 245
G Y G C+
Sbjct: 2646 G--YGGGLCM 2653
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 255 bits (652), Expect = 7e-68
Identities = 167/569 (29%), Positives = 248/569 (43%), Gaps = 81/569 (14%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
++LP +G++ ++ + +E+ + V Y + + + + Y+ GLCG YN
Sbjct: 795 VELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNA 854
Query: 61 DPKDDFQKPNGSQAGNANEFGNSW---EEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELE 117
+ D+F PNG N F SW EE+ C D + + EL
Sbjct: 855 NASDEFCLPNGKCTDNLAVFLESWTTFEEI-----------CNGECGDLLKACNNDSELL 903
Query: 118 KKYQKEEFCGLLSSPTGP-LSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSA 176
K Y+ CG+++ P+ CH +V+ + C+F LC GGN S LC ++ Y SA
Sbjct: 904 KFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASA 963
Query: 177 CQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSG 236
C+ A V PWRT FCP+ECP NSH+E C TC+ C L+ P C D C+EGCQCD G
Sbjct: 964 CKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETCETLTLGPICVDSCSEGCQCDEG 1022
Query: 237 FLYNGQACVPIQQCGCYHNGVYYEPEQTVLID-NCRQQCTCH-AGKVVVCQEHSCKPGQV 294
+ G CV +CGC G +T +D +C+ C C V C+ CK +
Sbjct: 1023 YALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEY 1082
Query: 295 CQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQET 354
C GG+ C R+ A V G + ++G P
Sbjct: 1083 CMEEGGLYYC----QARTDASCIVSGYGHYLTFDGFPF---------------------- 1116
Query: 355 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 414
+++ +C L +L TTG S+ F
Sbjct: 1117 ------------DFQTSCPL----------------------ILCTTG-SRPSSDSFPKF 1141
Query: 415 TVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 474
VT KN++R +V+ V V G +I IH+ V VN LP+ + G+I++
Sbjct: 1142 VVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIF 1201
Query: 475 QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP 534
++ DFGL+V YDW + +T+P S + GLCG + NP++D P G LA
Sbjct: 1202 SFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLAS 1261
Query: 535 SIPIWGGSWRAPGWDPLCWDECRGSCPTC 563
S+ +G SW D C C CP+C
Sbjct: 1262 SVNEFGQSWVKR--DTFCQVGCGDRCPSC 1288
Score = 247 bits (631), Expect = 2e-65
Identities = 161/571 (28%), Positives = 240/571 (42%), Gaps = 87/571 (15%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LPV L G ++ Q G +ETDFGL V +D +Y ++VPG+Y CGLCGNYN +P
Sbjct: 409 LPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNP 468
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPS-HKCPPELEKKYQ 121
DDF +P+G A + + G SW D C C+ + +C E Y
Sbjct: 469 LDDFLRPDGRPAMSVLDLGESWRVYHADWKC---------DSGCVDNCTQCDAATEALYF 519
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
++CG L+ GPL C +VDP + C++DLC N ++LC I AY CQA G
Sbjct: 520 GSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALG 579
Query: 182 GHVEPWRTETFC--PMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 239
+ WRT+T C ++CP SHY +C +C CS L+A C C EGC+C+ GF+
Sbjct: 580 IPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVL 639
Query: 240 NGQACVPIQQCGCYHNGVYYE-PEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPS 298
+ CVP+ +CGC +G YY E NC QC C G V C +C G+VC
Sbjct: 640 STSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVE 699
Query: 299 GGILSCVTK---VTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETC 355
G C K V L S Q +GA+ + + LL +TC
Sbjct: 700 DGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLL----------------KTC 743
Query: 356 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 415
E+ P Y D
Sbjct: 744 PER-------------------PEYLEID------------------------------- 753
Query: 416 VTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQ 475
K + PA ++R + + + I +V++NG LP G++ + +
Sbjct: 754 -INKKKPDAGPA--WLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYR 810
Query: 476 GASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS 535
+ + + + V Y + + L ++Y GLCG + N +++ PNG +
Sbjct: 811 NKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDN 870
Query: 536 IPIWGGSWRAPGWDPLCWDECRGSCPTCPED 566
+ ++ SW ++ +C EC C D
Sbjct: 871 LAVFLESWTT--FEEICNGECGDLLKACNND 899
Score = 246 bits (628), Expect = 4e-65
Identities = 120/315 (38%), Positives = 163/315 (51%), Gaps = 11/315 (3%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
LP+ L G+I G VV+ETDFGL+V YD ++ +TVP + GLCG YNG+P
Sbjct: 1189 LPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNP 1248
Query: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQK 122
DD + P G A + NEFG SW + T C G D PS C ++E +
Sbjct: 1249 DDDLEMPMGLLASSVNEFGQSWVK--------RDTFCQVGCGDRCPS--CA-KVEGFSKV 1297
Query: 123 EEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGG 182
++ C L+ + S CH V+P K+C+FD C+ GG + CS + Y S CQ G
Sbjct: 1298 QQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGI 1357
Query: 183 HVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQ 242
V WR T C + CPPNSHYE C C C+A+ C C EGC CD+G++ NG+
Sbjct: 1358 TVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGK 1417
Query: 243 ACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGIL 302
+C+ CGCY +G YYEP+Q +C ++C C V+ C CK + C G+
Sbjct: 1418 SCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVR 1477
Query: 303 SCVTKVTLRSLAQTG 317
C + T LA G
Sbjct: 1478 GCFSTKTSYCLAAGG 1492
Score = 159 bits (401), Expect = 9e-39
Identities = 90/249 (36%), Positives = 134/249 (53%), Gaps = 4/249 (1%)
Query: 344 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 403
C +C P E C+ +G C +TC ++G+PHYH+FDG F FQG+C Y+LA C
Sbjct: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ-C 352
Query: 404 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 463
+ T L F+V KN++R AVS+V+ ++V G I I K G+V+VN ++T+LP
Sbjct: 353 --LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLP 410
Query: 464 VSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 523
V++ G + + Q + DFGL V++D +++P SY + CGLCGN ++NP +
Sbjct: 411 VTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLD 470
Query: 524 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGLDE-GSLSDH 582
D + P+G A S+ G SWR D C C +C C Y G D G L+
Sbjct: 471 DFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKT 530
Query: 583 KDKIFMCYT 591
++ C T
Sbjct: 531 DGPLWECGT 539
Score = 67.8 bits (164), Expect = 3e-11
Identities = 52/218 (23%), Positives = 87/218 (39%), Gaps = 31/218 (14%)
Query: 21 VVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 80
+VI+T +++ Y+ +++++ ++CGLCGN+NGD DD+ G ++
Sbjct: 1588 LVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVL 1647
Query: 81 GNSWEEVVPDSPCLPPTPCPPGSEDCIPSH---KCPPELEKKYQKEEFCGLLSSPTGPLS 137
SW+ + + P P + S C +K Q + +C L+ G
Sbjct: 1648 AQSWK-----TNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQ 1702
Query: 138 SCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP--- 194
C+ L+DP + C D C LC ++ AY AC++ G W + C
Sbjct: 1703 PCYGLLDPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEKENCSGVV 1761
Query: 195 ------MECPPNSHYELCADTCSLG-----CSALSAPP 221
+CP TC LG C + PP
Sbjct: 1762 EDPCVGADCPNR--------TCELGNGRELCGCIEPPP 1791
Score = 38.5 bits (88), Expect = 0.018
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 251 GCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQVCQPSGGILSC 304
GC G + + D NC +C C + CQE SC P +VC+P G C
Sbjct: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYC 314
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 192 bits (489), Expect = 6e-49
Identities = 161/591 (27%), Positives = 234/591 (39%), Gaps = 92/591 (15%)
Query: 7 LANGQIRASQHGSDVVIETDFG--LRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKD 64
L G +R QH + +G L++ +D + V + Y + CGLCGNYNG+ D
Sbjct: 475 LLKGDLRI-QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGD 533
Query: 65 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQK-- 122
DF P+G +FGN+W+ +D H P L + +
Sbjct: 534 DFLTPSGLAEPRVEDFGNAWK-------------LHGDCQDLQKQHSDPCALNPRMTRFS 580
Query: 123 EEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGG 182
EE C +L+SPT +CH+ V P L++C +D+C LC + +Y +AC G
Sbjct: 581 EEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAGRGV 638
Query: 183 HVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAP-PQCQDGCAEGCQCDSGFLYNG 241
V WR C + CP Y C C+L C +LS P +C + C EGC C G +
Sbjct: 639 RV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLYMDE 697
Query: 242 QA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQ--------------- 285
+ CVP QC CY++G ++PE + + C C G +
Sbjct: 698 RGDCVPKAQCPCYYDGEIFQPED--IFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLSS 755
Query: 286 --EHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKV------LLP 337
H K C+P L C +L G++ Y+ + + + L P
Sbjct: 756 PLSHRSKRSLSCRPPMVKLVCPAD----NLRAEGLECTKTCQNYDLECMSMGCVSGCLCP 811
Query: 338 -----------LLSPDPC--HGVTCRPQETCKEQGGQGVCLPN--------YEATCWLWG 376
L PC G P ET K VC +ATC G
Sbjct: 812 PGMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIG 871
Query: 377 DPHYHSFDGRKFDFQGTCNYVLATTGC---PGVSTQGLTPFTVTTKNQNRGNPAVSYVRV 433
HY +FDG K+ F G C YVL C PG F + N+ +P+V +
Sbjct: 872 MAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGT-------FRILVGNKGCSHPSVKCKKR 924
Query: 434 VTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYD 493
VT+ G I + E+ R P+ + V + +L+ L V +D
Sbjct: 925 VTILVEGGEIELFDGEVNVKR--------PMK-DETHFEVVESGRYIILLLGKALSVVWD 975
Query: 494 WNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
+ + V L +Y VCGLCGN D NND N + +G SW+
Sbjct: 976 RHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWK 1026
Score = 131 bits (329), Expect = 2e-30
Identities = 139/513 (27%), Positives = 192/513 (37%), Gaps = 107/513 (20%)
Query: 40 RVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPC 99
+V + Y+ + CGLCGN+N +DDF G+ + +F NSW + C
Sbjct: 147 QVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWC--ERAS 204
Query: 100 PPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLG 159
PP S I S E++K ++ C LL S T + CH LVDP+ + C LC
Sbjct: 205 PPSSSCNISSG----EMQKGLWEQ--CQLLKS-TSVFARCHPLVDPEPFVALCEKTLCEC 257
Query: 160 GGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSA 219
G L C + Y C G + W + C CP Y
Sbjct: 258 AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYR--------------- 302
Query: 220 PPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAG 279
QC CA CQ L+ + C + C C+C G
Sbjct: 303 --QCVSPCARTCQS----LHINEMCQ----------------------ERCVDGCSCPEG 334
Query: 280 KVV---VCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLL 336
+++ +C E + P C SG T
Sbjct: 335 QLLDEGLCVESTECP---CVHSGKRYPPGTS----------------------------- 362
Query: 337 PLLSPDPCHGVTCR-PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 395
LS D C+ CR Q C + G CL + G H+ SFD R F F G C
Sbjct: 363 --LSRD-CNTCICRNSQWICSNEECPGECL--------VTGQSHFKSFDNRYFTFSGICQ 411
Query: 396 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGK-VR 454
Y+LA C S + T AV R VTV G + S+ K + G V
Sbjct: 412 YLLARD-CQDHSFS----IVIETVQCADDRDAVC-TRSVTVRLPGLHNSLVKLKHGAGVA 465
Query: 455 VNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLC 514
++G LP+ D RI T AS L + LQ+ +D R+ V L Y G CGLC
Sbjct: 466 MDGQDVQLPLLKGDLRIQHTVTASVRLSYGE-DLQMDWDGRGRLLVKLSPVYAGKTCGLC 524
Query: 515 GNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG 547
GN + N +D + P+G P + +G +W+ G
Sbjct: 525 GNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHG 557
Score = 107 bits (268), Expect = 2e-23
Identities = 83/300 (27%), Positives = 123/300 (41%), Gaps = 28/300 (9%)
Query: 16 QHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAG 75
+ G +++ L V +D + V + Y +++CGLCGN++G +D N
Sbjct: 957 ESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEE 1016
Query: 76 NANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGP 135
+ +FGNSW+ S C P S C + K+ + C +L+S
Sbjct: 1017 DPVDFGNSWK---VSSQCADTRKVPLDSSPA----TCHNNIMKQTMVDSSCRILTSDV-- 1067
Query: 136 LSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFC 193
C+KLVDP+ L CI+D C G+ + C I AY C A G V WRT T C
Sbjct: 1068 FQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC-AQHGKVVTWRTATLC 1126
Query: 194 PMECPPNS----------HYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSGFLYN 240
P C + Y CA C + C L+ P QC +GC C
Sbjct: 1127 PQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKILDEL 1186
Query: 241 GQACVPIQQCG-CYHNGVYYEPEQTVLID-NCRQQC-TCHAGKVVVCQEHSCKPGQVCQP 297
Q CV + C C G + + V ++ + + C CH V + E +PG + P
Sbjct: 1187 LQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCEACQEPGGLVVP 1246
Score = 76.3 bits (186), Expect = 8e-14
Identities = 66/250 (26%), Positives = 98/250 (39%), Gaps = 31/250 (12%)
Query: 44 PGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGS 103
P + + GLCG + + +DF +G+ + W P C P
Sbjct: 2074 PKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPIL-----E 2128
Query: 104 EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL 163
E C+ C +L P + CHK++ P C D C +
Sbjct: 2129 EQCL------------VPDSSHCQVLLLPL--FAECHKVLAPATFYAICQQDSC----HQ 2170
Query: 164 SILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQC 223
+C I +Y C+ G V+ WRT FC M CPP+ Y C C C + C
Sbjct: 2171 EQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVS--SC 2227
Query: 224 QDGCAEGCQCDSGFLYNGQACVPIQQC-GCY-HNGVYYEPEQTVLIDN--CRQQCTCHAG 279
D +EGC C + +CVP + C C +GV ++ + + D+ C Q CTC +G
Sbjct: 2228 GDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPC-QICTCLSG 2286
Query: 280 KVVVCQEHSC 289
+ V C C
Sbjct: 2287 RKVNCTTQPC 2296
Score = 54.7 bits (130), Expect = 2e-07
Identities = 48/183 (26%), Positives = 70/183 (38%), Gaps = 15/183 (8%)
Query: 370 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 429
A C L+G ++FDG + F G C+Y+LA GC S F++ QN ++S
Sbjct: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKRVSLS 85
Query: 430 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 489
LG IH G V ++P + + G T+ L +G
Sbjct: 86 VY-------LGEFFDIHLFVNGTVTQGDQRVSMPYA-SKGLYLETEAGYYKLSGEAYGFV 137
Query: 490 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 549
D + V L Y CGLCGN + +D + GTL + SW +
Sbjct: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
Query: 550 PLC 552
C
Sbjct: 198 QWC 200
Score = 43.9 bits (102), Expect = 4e-04
Identities = 60/246 (24%), Positives = 94/246 (38%), Gaps = 40/246 (16%)
Query: 341 PDPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP------- 378
PD CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 1896 PDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSS 1954
Query: 379 --HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTV 436
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 1955 TRHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEV 2007
Query: 437 AALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSY-DWN 495
++ +H D +V VNG L ++P + ++V + G ++ N
Sbjct: 2008 KHSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQN 2065
Query: 496 WRVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW--RAPG--WDP 550
+ L P ++ GLCG D N ND + +GT+ W + PG P
Sbjct: 2066 NEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQP 2125
Query: 551 LCWDEC 556
+ ++C
Sbjct: 2126 ILEEQC 2131
Score = 32.7 bits (73), Expect = 0.97
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 13/71 (18%)
Query: 233 CDSGFLYNGQ--ACVPIQQC----GCYHNGVYYEPEQTVLIDNCRQQCTCH------AGK 280
C SGF + + AC P +C C NG P +TV+ID C C C +G
Sbjct: 2557 CPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVC-TTCRCMVQVGVISGF 2615
Query: 281 VVVCQEHSCKP 291
+ C++ +C P
Sbjct: 2616 KLECRKTTCNP 2626
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 181 bits (459), Expect = 2e-45
Identities = 158/613 (25%), Positives = 239/613 (38%), Gaps = 120/613 (19%)
Query: 21 VVIETDFGLRVAYDLVYYVRVTVPGN--YYQQMCGLCGNYNGDPKDDFQKPNGSQAGNAN 78
+V++T GL++ LV ++V V + + QMCGLCGN+N + DDF +G
Sbjct: 1185 IVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGA 1244
Query: 79 EFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 138
F N+W+ + P C +E + +C L+ P S
Sbjct: 1245 AFANTWKAQAACANARNSFEDP-----------CSLSVENENYARHWCSRLTDPNSAFSR 1293
Query: 139 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTE--TFCPME 196
CH +++P+ +C+FD C + LC+ + +YV AC A G + WR T
Sbjct: 1294 CHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQN 1353
Query: 197 CPPNSHYELCADTCSLGCSALS-APPQCQDGC--AEGCQCDSG-FLYNGQACVPIQQCGC 252
CP + Y D C C LS A C +GC C +G FL + ACVP Q+C C
Sbjct: 1354 CPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC 1413
Query: 253 YHNGVYYEPEQTVLIDNCRQQCTCHAGKV------------------------------- 281
Y +G P + V + C+C GK+
Sbjct: 1414 YAHGTVLAPGEVVHDEGA--VCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPG 1471
Query: 282 -----------VVCQEHSCKPGQVCQP---SGGILSCVTKVTLRSLAQTGVDVEGAAILY 327
V C C G VC P S G C+ + + V A
Sbjct: 1472 AECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAE-------EDCPCVHNEATYK 1524
Query: 328 NGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRK 387
G+ ++V C+ TCR + + + +CL TC +GD H+ +FDG +
Sbjct: 1525 PGETIRV--------DCNTCTCRNR---RWECSHRLCL----GTCVAYGDGHFITFDGDR 1569
Query: 388 FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS-------YVRVVTVAALG 440
+ F+G+C Y+LA C +T G F + T+N G + +V V T A+
Sbjct: 1570 YSFEGSCEYILAQDYCGDNTTHG--TFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVS 1627
Query: 441 TNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA-------------------L 481
T + + G LP + + + +G KA L
Sbjct: 1628 TPDPAANEPAPREASVGFRQRLP-PLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFL 1686
Query: 482 LVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 541
++ G+ VS+D V + L Y G VCGLCGN D N ND + ++ +G
Sbjct: 1687 VIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGN 1746
Query: 542 SWRAPGWDPLCWD 554
SW+ P C D
Sbjct: 1747 SWKL---SPSCPD 1756
Score = 125 bits (314), Expect = 1e-28
Identities = 98/304 (32%), Positives = 128/304 (42%), Gaps = 29/304 (9%)
Query: 4 PVVLANGQ--IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGD 61
PV+L Q + Q S +E GL + ++ + + + Y + CGLCG++NG
Sbjct: 158 PVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGM 217
Query: 62 PKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
P + ++ EFGN + P C P P PP +C EL
Sbjct: 218 PVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDPVPEPP--RNCSTGFGICEEL----- 269
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGN--LSILCSNIHAYVSACQA 179
G L S C LVD L+ C DLC LS +C + Y C
Sbjct: 270 ---LHGQL------FSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTH 320
Query: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 239
AGG + WR FCP +CP N Y C C+ CS C+D C GC C G +
Sbjct: 321 AGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVL 380
Query: 240 N--GQ-ACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQ 296
+ GQ CVP+ +C C +NG Y P T D C CTC G+ CQE C PG C
Sbjct: 381 DDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-C-TNCTCSGGR-WSCQEVPC-PG-TCS 435
Query: 297 PSGG 300
GG
Sbjct: 436 VLGG 439
Score = 110 bits (276), Expect = 3e-24
Identities = 85/267 (31%), Positives = 108/267 (40%), Gaps = 45/267 (16%)
Query: 47 YYQQMCGLCGNYNGDPKDDFQKPNGSQAGNAN----EFGNSWEEVVPDSPCLPPTPCPPG 102
Y Q CGLCG++NG P N A NA +FGN + P C P P P G
Sbjct: 855 YANQTCGLCGDFNGLPAF-----NEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPLPAG 909
Query: 103 SEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGP-LSSCHKLVDPQGPLKDCIFDLCLGGG 161
+ C E E C + GP + CH LVD L C DLC
Sbjct: 910 N--------CTDE-------EGICH--RTLLGPAFAECHALVDSTAYLAACAQDLCRCP- 951
Query: 162 NLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP 221
+ C+ Y C AGG WR CP CP N ++ C C+ CS
Sbjct: 952 --TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQ 1009
Query: 222 QCQDGCAEGCQCDSG--------FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQ 273
C+D C +GC C G ++G C+P+ QC C H G Y P + +
Sbjct: 1010 LCEDHCVDGCFCPPGRSCTVLDDITHSG--CLPLGQCPCTHGGRTYSPGTS--FNTTCSS 1065
Query: 274 CTCHAGKVVVCQEHSCKPGQVCQPSGG 300
CTC +G + CQ+ C PG C GG
Sbjct: 1066 CTC-SGGLWQCQDLPC-PG-TCSVQGG 1089
Score = 108 bits (271), Expect = 1e-23
Identities = 87/276 (31%), Positives = 125/276 (45%), Gaps = 37/276 (13%)
Query: 18 GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNA 77
G +VIET G+ V++D V + + +Y ++CGLCGN++ + +DF + S G+A
Sbjct: 1683 GIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDA 1741
Query: 78 NEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLS 137
EFGNSW+ L P+ CP + P C +K ++ C +L PT +
Sbjct: 1742 LEFGNSWK--------LSPS-CP---DALAPKDPCTANPFRKSWAQKQCSILHGPT--FA 1787
Query: 138 SCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPM 195
+C VD + C+ D C GG+ C+ + AY AC AG V WRT CP+
Sbjct: 1788 ACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPL 1846
Query: 196 ECP---PNS----HYELCADTCSLGCSALSAPPQC------QDGCAEGCQCDSGFLYNGQ 242
C P+ HY+ C C C S C +GC C F +N
Sbjct: 1847 FCDFYNPHGGCEWHYQPCGAPCLKTCRNPSG--HCLVDLPGLEGCYPKCPPSQPF-FNED 1903
Query: 243 ACVPIQQCGCY-HNGVYYEPEQTV-LIDNCRQQCTC 276
+ QCGCY +G YY+ V +NC Q C C
Sbjct: 1904 QMKCVAQCGCYDKDGNYYDVGARVPTAENC-QSCNC 1938
Score = 103 bits (256), Expect = 6e-22
Identities = 75/251 (29%), Positives = 105/251 (41%), Gaps = 33/251 (13%)
Query: 53 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP---CLPPTPCPPGSEDCIPS 109
G CG + +DD + +G+ A + + +W +VPDS C PT PP + P
Sbjct: 5556 GQCGTCTNNQRDDCLQRDGTTAASCKDMAKTW--LVPDSRKDGCWAPTGTPPTASPAAPV 5613
Query: 110 HK------CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL 163
CPP+ C L+ S + CH LV P CI D C G L
Sbjct: 5614 SSTPTPTPCPPQ--------PLCDLMLSQV--FAECHNLVPPGPFFNACISDHCRG--RL 5661
Query: 164 SILCSNIHAYVSACQAAGGHVEPWRTET--FCPMECPPNSHYELCADTCSLGCSALSAPP 221
+ C ++ AY C+A G WR T C + CPP Y+ C C++ + P
Sbjct: 5662 EVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSP 5720
Query: 222 QCQDGCAEGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280
Q +G AEGC C + L+N + +Q C C + + + NC Q C C G
Sbjct: 5721 QL-EGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGS 5778
Query: 281 VVVCQEHSCKP 291
V V CKP
Sbjct: 5779 VSV----QCKP 5785
Score = 55.8 bits (133), Expect = 1e-07
Identities = 46/160 (28%), Positives = 71/160 (44%), Gaps = 12/160 (7%)
Query: 372 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 431
C WG HY +FDG F F G CNYV + C G + + ++Q P +S
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVF-SEHC-GAAYEDFN--IQLRRSQESAAPTLSR- 135
Query: 432 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 491
V + G I + K G V VNG LP S + + Q +S + A GL +
Sbjct: 136 --VLMKVDGVVIQLTK---GSVLVNGHPVLLPFS--QSGVLIQQSSSYTKVEARLGLVLM 188
Query: 492 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 531
++ + + + L + Y CGLCG+ + P ++ + T
Sbjct: 189 WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNT 228
Score = 53.5 bits (127), Expect = 5e-07
Identities = 76/340 (22%), Positives = 120/340 (35%), Gaps = 57/340 (16%)
Query: 250 CGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEH-----------------SCKPG 292
C C G ++ P + + R C +A VC +H S P
Sbjct: 5265 CFCRAFGQFFSPGEVIYNKTDRAGCHFYA----VCNQHCDIDRFQGACPTSPPPVSSAPL 5320
Query: 293 QVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTC--- 349
P+ G C + LR + +T +E + +V+L L P P VTC
Sbjct: 5321 SSPSPAPG---CDNAIPLRQVNETWT-LENCTVARCVGDNRVVL--LDPKPVANVTCVNK 5374
Query: 350 -------RPQETCKEQ--------GGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTC 394
P + C GG+G+ P C +WG HY +FDG + F+G C
Sbjct: 5375 HLPIKVSDPSQPCDFHYECECECVGGRGIT-PG-AGICSMWGGSHYSTFDGTSYTFRGNC 5432
Query: 395 NYVLATTGCPGVSTQGL------TPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKD 448
YVL L + T P + ++ + T +H
Sbjct: 5433 TYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGK 5492
Query: 449 EIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRV-DVTLP-SSY 506
E G + + + + S +SV + + + G+ V++ N +V LP S +
Sbjct: 5493 EEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTF--NGQVFQARLPYSLF 5550
Query: 507 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP 546
H G CG N +D + +GT A S +W P
Sbjct: 5551 HNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVP 5590
Score = 52.0 bits (123), Expect = 2e-06
Identities = 47/166 (28%), Positives = 65/166 (39%), Gaps = 17/166 (10%)
Query: 372 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 431
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 785
Query: 432 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 491
V + A G + G V +NG LP S R + S + L ++
Sbjct: 786 TRVVIKAQGLVLEASN---GSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLVLT 838
Query: 492 YDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAP 534
+ WN + L Y CGLCG+ + P ++ + N L P
Sbjct: 839 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP 884
Score = 37.0 bits (84), Expect = 0.051
Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 21 VVIETDFGLRVAYDLVYYVRV--TVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNAN 78
++ +T GL++ LV +++ + Q CGLCGN+N DDF+ +G A
Sbjct: 535 IIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAA 594
Query: 79 EFGNSWE 85
F N+++
Sbjct: 595 AFFNTFK 601
Score = 31.2 bits (69), Expect = 2.8
Identities = 27/94 (28%), Positives = 35/94 (37%), Gaps = 29/94 (30%)
Query: 90 DSPCLPPTPC--------------PPGSE--------DCIPSHKCPPELEKKYQKEEFCG 127
++PC P T C PPG E DC P+ +C P+L F G
Sbjct: 5811 ENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCS--YNGTFYG 5868
Query: 128 LLSSPTGPLSSCHKLV----DPQGPLKDCIFDLC 157
+ ++ G L CH D Q P C D C
Sbjct: 5869 VGATFPGAL-PCHMCTCLSGDTQDPTVQCQEDAC 5901
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 178 bits (452), Expect = 1e-44
Identities = 151/587 (25%), Positives = 228/587 (38%), Gaps = 102/587 (17%)
Query: 21 VVIETDFGLRVAYDLVYYVRVTVPGN--YYQQMCGLCGNYNGDPKDDFQKPNGSQAGNAN 78
+V++T GL++ LV ++V V + + QMCGLCGN+N + DDF +G
Sbjct: 529 IVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGA 588
Query: 79 EFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 138
F N+W+ + P C +E + +C L+ P S
Sbjct: 589 AFANTWKAQAACANARNSFEDP-----------CSLSVENENYARHWCSRLTDPNSAFSR 637
Query: 139 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTE--TFCPME 196
CH +++P+ +C+FD C + LC+ + +YV AC A G + WR T
Sbjct: 638 CHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQN 697
Query: 197 CPPNSHYELCADTCSLGCSALS-APPQCQDGC--AEGCQCDSG-FLYNGQACVPIQQCGC 252
CP + Y D C C LS A C +GC C +G FL + ACVP Q+C C
Sbjct: 698 CPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPC 757
Query: 253 YHNGVYYEPEQTVLIDNCRQQCTCHAGKV------------------------------- 281
Y +G P + V + C+C GK+
Sbjct: 758 YAHGTVLAPGEVVHDEGA--VCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPG 815
Query: 282 -----------VVCQEHSCKPGQVCQP---SGGILSCVTKVTLRSLAQTGVDVEGAAILY 327
V C C G VC P S G C+ + + V A
Sbjct: 816 AECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAE-------EDCPCVHNEATYK 868
Query: 328 NGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRK 387
G+ ++V C+ TCR + + + +CL TC +GD H+ +FDG +
Sbjct: 869 PGETIRV--------DCNTCTCRNR---RWECSHRLCL----GTCVAYGDGHFITFDGDR 913
Query: 388 FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHK 447
+ F+G+C Y+LA C +T G F + T+N G T I +
Sbjct: 914 YSFEGSCEYILAQDYCGDNTTHG--TFRIVTENIPCG---------TTGTTCSKAIKLFV 962
Query: 448 DEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH 507
+ + G A+ + L++ G+ VS+D V + L Y
Sbjct: 963 ESYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYK 1022
Query: 508 GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWD 554
G VCGLCGN D N ND + ++ +G SW+ P C D
Sbjct: 1023 GRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKL---SPSCPD 1066
Score = 110 bits (276), Expect = 3e-24
Identities = 85/267 (31%), Positives = 108/267 (40%), Gaps = 45/267 (16%)
Query: 47 YYQQMCGLCGNYNGDPKDDFQKPNGSQAGNAN----EFGNSWEEVVPDSPCLPPTPCPPG 102
Y Q CGLCG++NG P N A NA +FGN + P C P P P G
Sbjct: 199 YANQTCGLCGDFNGLPAF-----NEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPLPAG 253
Query: 103 SEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGP-LSSCHKLVDPQGPLKDCIFDLCLGGG 161
+ C E E C + GP + CH LVD L C DLC
Sbjct: 254 N--------CTDE-------EGICH--RTLLGPAFAECHALVDSTAYLAACAQDLCRCP- 295
Query: 162 NLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP 221
+ C+ Y C AGG WR CP CP N ++ C C+ CS
Sbjct: 296 --TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQ 353
Query: 222 QCQDGCAEGCQCDSG--------FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQ 273
C+D C +GC C G ++G C+P+ QC C H G Y P + +
Sbjct: 354 LCEDHCVDGCFCPPGRSCTVLDDITHSG--CLPLGQCPCTHGGRTYSPGTS--FNTTCSS 409
Query: 274 CTCHAGKVVVCQEHSCKPGQVCQPSGG 300
CTC +G + CQ+ C PG C GG
Sbjct: 410 CTC-SGGLWQCQDLPC-PG-TCSVQGG 433
Score = 108 bits (271), Expect = 1e-23
Identities = 87/276 (31%), Positives = 125/276 (45%), Gaps = 37/276 (13%)
Query: 18 GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNA 77
G +VIET G+ V++D V + + +Y ++CGLCGN++ + +DF + S G+A
Sbjct: 993 GIFLVIETH-GMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDA 1051
Query: 78 NEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLS 137
EFGNSW+ L P+ CP + P C +K ++ C +L PT +
Sbjct: 1052 LEFGNSWK--------LSPS-CP---DALAPKDPCTANPFRKSWAQKQCSILHGPT--FA 1097
Query: 138 SCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPM 195
+C VD + C+ D C GG+ C+ + AY AC AG V WRT CP+
Sbjct: 1098 ACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPL 1156
Query: 196 ECP---PNS----HYELCADTCSLGCSALSAPPQC------QDGCAEGCQCDSGFLYNGQ 242
C P+ HY+ C C C S C +GC C F +N
Sbjct: 1157 FCDFYNPHGGCEWHYQPCGAPCLKTCRNPSG--HCLVDLPGLEGCYPKCPPSQPF-FNED 1213
Query: 243 ACVPIQQCGCY-HNGVYYEPEQTV-LIDNCRQQCTC 276
+ QCGCY +G YY+ V +NC Q C C
Sbjct: 1214 QMKCVAQCGCYDKDGNYYDVGARVPTAENC-QSCNC 1248
Score = 103 bits (256), Expect = 6e-22
Identities = 75/251 (29%), Positives = 105/251 (41%), Gaps = 33/251 (13%)
Query: 53 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP---CLPPTPCPPGSEDCIPS 109
G CG + +DD + +G+ A + + +W +VPDS C PT PP + P
Sbjct: 5222 GQCGTCTNNQRDDCLQRDGTTAASCKDMAKTW--LVPDSRKDGCWAPTGTPPTASPAAPV 5279
Query: 110 HK------CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL 163
CPP+ C L+ S + CH LV P CI D C G L
Sbjct: 5280 SSTPTPTPCPPQ--------PLCDLMLSQV--FAECHNLVPPGPFFNACISDHCRG--RL 5327
Query: 164 SILCSNIHAYVSACQAAGGHVEPWRTET--FCPMECPPNSHYELCADTCSLGCSALSAPP 221
+ C ++ AY C+A G WR T C + CPP Y+ C C++ + P
Sbjct: 5328 EVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSP 5386
Query: 222 QCQDGCAEGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280
Q +G AEGC C + L+N + +Q C C + + + NC Q C C G
Sbjct: 5387 QL-EGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGS 5444
Query: 281 VVVCQEHSCKP 291
V V CKP
Sbjct: 5445 VSV----QCKP 5451
Score = 56.2 bits (134), Expect = 8e-08
Identities = 77/324 (23%), Positives = 121/324 (37%), Gaps = 40/324 (12%)
Query: 250 CGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEH-----------------SCKPG 292
C C G ++ P + + R C +A VC +H S P
Sbjct: 4946 CFCRAFGQFFSPGEVIYNKTDRAGCHFYA----VCNQHCDIDRFQGACPTSPPPVSSAPL 5001
Query: 293 QVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQ 352
P+ G C + LR + +T +E + +V+L L P P VTC +
Sbjct: 5002 SSPSPAPG---CDNAIPLRQVNETWT-LENCTVARCVGDNRVVL--LDPKPVANVTCVNK 5055
Query: 353 ET-CKEQGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVL-----ATTGCP 404
K C +YE C +WG HY +FDG + F+G C YVL A G
Sbjct: 5056 HLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNL 5115
Query: 405 GVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPV 464
+ T R A+S + ++ + T +H E G + + + +
Sbjct: 5116 SLYLDNHYCTASATAAAARCPRALS-IHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGF 5174
Query: 465 SVADGRISVTQGASKALLVADFGLQVSYDWNWRV-DVTLP-SSYHGAVCGLCGNMDRNPN 522
S +SV + + + G+ V++ N +V LP S +H G CG N
Sbjct: 5175 SKNGVLVSVLGTTTMRVDIPALGVSVTF--NGQVFQARLPYSLFHNNTEGQCGTCTNNQR 5232
Query: 523 NDQVFPNGTLAPSIPIWGGSWRAP 546
+D + +GT A S +W P
Sbjct: 5233 DDCLQRDGTTAASCKDMAKTWLVP 5256
Score = 52.0 bits (123), Expect = 2e-06
Identities = 47/166 (28%), Positives = 65/166 (39%), Gaps = 17/166 (10%)
Query: 372 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 431
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 129
Query: 432 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 491
V + A G + G V +NG LP S R + S + L ++
Sbjct: 130 TRVVIKAQGLVLEASN---GSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLVLT 182
Query: 492 YDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAP 534
+ WN + L Y CGLCG+ + P ++ + N L P
Sbjct: 183 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP 228
Score = 31.2 bits (69), Expect = 2.8
Identities = 27/94 (28%), Positives = 35/94 (37%), Gaps = 29/94 (30%)
Query: 90 DSPCLPPTPC--------------PPGSE--------DCIPSHKCPPELEKKYQKEEFCG 127
++PC P T C PPG E DC P+ +C P+L F G
Sbjct: 5477 ENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCS--YNGTFYG 5534
Query: 128 LLSSPTGPLSSCHKLV----DPQGPLKDCIFDLC 157
+ ++ G L CH D Q P C D C
Sbjct: 5535 VGATFPGAL-PCHMCTCLSGDTQDPTVQCQEDAC 5567
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 177 bits (448), Expect = 3e-44
Identities = 163/600 (27%), Positives = 235/600 (39%), Gaps = 78/600 (13%)
Query: 1 MKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYN 59
+ LP V A+ + R S + V + L+V V + VT+ Q+ GLCGN+N
Sbjct: 473 VNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFN 532
Query: 60 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKK 119
G DDF+ +G F N+W+ L P C +E
Sbjct: 533 GLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDP-----------CSLNIESA 581
Query: 120 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
E +C LL P CH VDP K C +D C N LC+ + +Y AC A
Sbjct: 582 NYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTA 641
Query: 180 AGGHVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALS-APPQCQDGCA--EGCQC 233
G + WR E C + CP + + TC C +LS A C +G A +GC C
Sbjct: 642 KGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGC 700
Query: 234 -DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQ----EHS 288
D FL CVP+ +C CYH G+Y E V+ ++C C G++ Q S
Sbjct: 701 PDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV--RQEERCVCRDGRLHCRQIRLIGQS 758
Query: 289 CKPGQVCQPSGGILSCVTKVTLRSLAQTGV--------------------DVEGAAILYN 328
C ++ + + T QT D G ++
Sbjct: 759 CTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEK 818
Query: 329 GQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNY-EATCWLWGDPHYHSFDGRK 387
P L S V C TC + G+ VC TC ++G HY +FDG+
Sbjct: 819 ECPCVHNNDLYSSGAKIKVDC---NTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKY 875
Query: 388 FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIH- 446
+DF G C+YV C S+ G F++ T+N G V+ + + + T + +
Sbjct: 876 YDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTELKLED 933
Query: 447 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV-ADFGLQVSYDWNWRVDVTLPSS 505
K + R G A T+ + L+V + G+ V +D V + L S
Sbjct: 934 KHRVVIQRDEGHHVAY----------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPS 983
Query: 506 YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPE 565
Y G VCGLCGN D NND + + S +G SW+ PTCP+
Sbjct: 984 YKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK--------------EAPTCPD 1029
Score = 114 bits (284), Expect = 3e-25
Identities = 80/288 (27%), Positives = 120/288 (41%), Gaps = 30/288 (10%)
Query: 18 GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNA 77
G +V+E+ G+ V +D V + + +Y +CGLCGN++ +DF + +
Sbjct: 955 GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 1014
Query: 78 NEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLS 137
+FGNSW+E P P + P P C ++ E+ C +L S S
Sbjct: 1015 LDFGNSWKE-APTCPDVSTNPEP-----------CSLNPHRRSWAEKQCSILKSSV--FS 1060
Query: 138 SCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPM 195
CH VDP+ + C+ D C GG+ CS + +Y C G V WRT CP+
Sbjct: 1061 ICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPI 1119
Query: 196 EC----PPNS---HYELCADTCSLGCSALSA-----PPQCQDGCAEGCQCDSGFLYNG-Q 242
C PP+ HYE C + C ++ +GC C D +
Sbjct: 1120 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLK 1179
Query: 243 ACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCK 290
CV +CGCY +Y P +V + + C C VVC+ K
Sbjct: 1180 KCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGK 1227
Score = 110 bits (275), Expect = 4e-24
Identities = 85/280 (30%), Positives = 118/280 (42%), Gaps = 32/280 (11%)
Query: 28 GLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEV 87
GL + ++ + + + + CGLCG+YNG +G EFGN +
Sbjct: 142 GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNMQKIN 200
Query: 88 VPDSPCLPPTPCPPGSEDCIPS----HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLV 143
PD C P E+ P+ H+ E E+ E F + C LV
Sbjct: 201 QPDVVCEDP------EEEVAPASCSEHRA--ECERLLTAEAF-----------ADCQDLV 241
Query: 144 DPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHY 203
+ L+ C D C G + +CS + + C AGG WRT T CP CP N Y
Sbjct: 242 PLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVY 301
Query: 204 ELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN---GQACVPIQQCGCYHNGVYYE 260
C CS L C++ +GC C G +Y+ CVP+ QC C +G Y
Sbjct: 302 LESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYT 361
Query: 261 PEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
P Q I N +QC C+AG+ VC++ C PG C GG
Sbjct: 362 PGQE--ITNDCEQCVCNAGR-WVCKDLPC-PG-TCALEGG 396
Score = 86.3 bits (212), Expect = 7e-17
Identities = 84/306 (27%), Positives = 119/306 (38%), Gaps = 35/306 (11%)
Query: 16 QHGSDVVIET-DFGLRVAYD-LVYYVRVTVP--GNYYQQMCGLCGNYNGDPKDDFQKPNG 71
Q G + V++ + G+ V+Y+ L + VR+ GN + CG C N D D P+G
Sbjct: 4582 QSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSD---DCILPSG 4638
Query: 72 SQAGNANEFGNSWEEVVPDSPCLP--------PTPCPPGSEDCIPSHKCPPELEKKYQKE 123
N + W P P P P PG P C P
Sbjct: 4639 EIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPS-------- 4690
Query: 124 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGH 183
C L+ + CH LV PQ C+FD C G+ S+ C+++ AY + C A
Sbjct: 4691 PLCQLIKDSL--FAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNI 4746
Query: 184 VEPWRTETF--CPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFL-YN 240
WR T C +ECP + Y+ C C + S+ Q EGC C G + Y
Sbjct: 4747 CLDWRNHTHGACLVECPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYA 4805
Query: 241 GQACVPIQQCGCY-HNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSC--KPGQVCQP 297
V ++ CGC + V E + D C+ G ++CQ C KP C
Sbjct: 4806 PGFDVCVKTCGCVGPDNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHCVE 4864
Query: 298 SGGILS 303
G L+
Sbjct: 4865 DGTYLA 4870
Score = 60.8 bits (146), Expect = 3e-09
Identities = 56/206 (27%), Positives = 81/206 (39%), Gaps = 19/206 (9%)
Query: 351 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 401
P TC G Q V + + + CW W GDPHY +FDG + +QG C YVL
Sbjct: 4452 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 4510
Query: 402 GCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 460
P V G+ N P VR T L + + ++ +V+VN
Sbjct: 4511 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAV 4569
Query: 461 ALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNM 517
ALP G G + + + + G+ VSY+ V LP YH G CG
Sbjct: 4570 ALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTC 4625
Query: 518 DRNPNNDQVFPNGTLAPSIPIWGGSW 543
++D + P+G + + W
Sbjct: 4626 TNTTSDDCILPSGEIVSNCEAAADQW 4651
Score = 45.1 bits (105), Expect = 2e-04
Identities = 51/218 (23%), Positives = 86/218 (39%), Gaps = 16/218 (7%)
Query: 372 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 431
C WG+ HY +FDG F F G C+Y A + C G F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFA-SDCRG----SYKEFAVHLKRGPGQAEAPAGV 91
Query: 432 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVTQGASKALLVADFGLQ 489
+ ++I D I R VL VS + + + + + + GL
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
Query: 490 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 549
+ ++ + + L + + CGLCG+ + + + +G L + +G + D
Sbjct: 145 LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
Query: 550 PLCWDECRGSCP-TCPEDRLEQYEGLDEGSLSDHKDKI 586
+C D P +C E R E L + +D +D +
Sbjct: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLV 241
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 177 bits (448), Expect = 3e-44
Identities = 163/600 (27%), Positives = 235/600 (39%), Gaps = 78/600 (13%)
Query: 1 MKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYN 59
+ LP V A+ + R S + V + L+V V + VT+ Q+ GLCGN+N
Sbjct: 374 VNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFN 433
Query: 60 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKK 119
G DDF+ +G F N+W+ L P C +E
Sbjct: 434 GLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDP-----------CSLNIESA 482
Query: 120 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
E +C LL P CH VDP K C +D C N LC+ + +Y AC A
Sbjct: 483 NYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTA 542
Query: 180 AGGHVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALS-APPQCQDGCA--EGCQC 233
G + WR E C + CP + + TC C +LS A C +G A +GC C
Sbjct: 543 KGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGC 601
Query: 234 -DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQ----EHS 288
D FL CVP+ +C CYH G+Y E V+ ++C C G++ Q S
Sbjct: 602 PDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV--RQEERCVCRDGRLHCRQIRLIGQS 659
Query: 289 CKPGQVCQPSGGILSCVTKVTLRSLAQTGV--------------------DVEGAAILYN 328
C ++ + + T QT D G ++
Sbjct: 660 CTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEK 719
Query: 329 GQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNY-EATCWLWGDPHYHSFDGRK 387
P L S V C TC + G+ VC TC ++G HY +FDG+
Sbjct: 720 ECPCVHNNDLYSSGAKIKVDC---NTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKY 776
Query: 388 FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIH- 446
+DF G C+YV C S+ G F++ T+N G V+ + + + T + +
Sbjct: 777 YDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTELKLED 834
Query: 447 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV-ADFGLQVSYDWNWRVDVTLPSS 505
K + R G A T+ + L+V + G+ V +D V + L S
Sbjct: 835 KHRVVIQRDEGHHVAY----------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPS 884
Query: 506 YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPE 565
Y G VCGLCGN D NND + + S +G SW+ PTCP+
Sbjct: 885 YKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWK--------------EAPTCPD 930
Score = 114 bits (284), Expect = 3e-25
Identities = 80/288 (27%), Positives = 120/288 (41%), Gaps = 30/288 (10%)
Query: 18 GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNA 77
G +V+E+ G+ V +D V + + +Y +CGLCGN++ +DF + +
Sbjct: 856 GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSE 915
Query: 78 NEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLS 137
+FGNSW+E P P + P P C ++ E+ C +L S S
Sbjct: 916 LDFGNSWKE-APTCPDVSTNPEP-----------CSLNPHRRSWAEKQCSILKSSV--FS 961
Query: 138 SCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPM 195
CH VDP+ + C+ D C GG+ CS + +Y C G V WRT CP+
Sbjct: 962 ICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPI 1020
Query: 196 EC----PPNS---HYELCADTCSLGCSALSA-----PPQCQDGCAEGCQCDSGFLYNG-Q 242
C PP+ HYE C + C ++ +GC C D +
Sbjct: 1021 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLK 1080
Query: 243 ACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCK 290
CV +CGCY +Y P +V + + C C VVC+ K
Sbjct: 1081 KCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCRPEEGK 1128
Score = 86.3 bits (212), Expect = 7e-17
Identities = 84/306 (27%), Positives = 119/306 (38%), Gaps = 35/306 (11%)
Query: 16 QHGSDVVIET-DFGLRVAYD-LVYYVRVTVP--GNYYQQMCGLCGNYNGDPKDDFQKPNG 71
Q G + V++ + G+ V+Y+ L + VR+ GN + CG C N D D P+G
Sbjct: 2042 QSGINYVVDIPELGVLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSD---DCILPSG 2098
Query: 72 SQAGNANEFGNSWEEVVPDSPCLP--------PTPCPPGSEDCIPSHKCPPELEKKYQKE 123
N + W P P P P PG P C P
Sbjct: 2099 EIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPS-------- 2150
Query: 124 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGH 183
C L+ + CH LV PQ C+FD C G+ S+ C+++ AY + C A
Sbjct: 2151 PLCQLIKDSL--FAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNI 2206
Query: 184 VEPWRTETF--CPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFL-YN 240
WR T C +ECP + Y+ C C + S+ Q EGC C G + Y
Sbjct: 2207 CLDWRNHTHGACLVECPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYA 2265
Query: 241 GQACVPIQQCGCY-HNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSC--KPGQVCQP 297
V ++ CGC + V E + D C+ G ++CQ C KP C
Sbjct: 2266 PGFDVCVKTCGCVGPDNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHCVE 2324
Query: 298 SGGILS 303
G L+
Sbjct: 2325 DGTYLA 2330
Score = 62.8 bits (151), Expect = 9e-10
Identities = 57/218 (26%), Positives = 81/218 (37%), Gaps = 29/218 (13%)
Query: 28 GLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEV 87
GL + ++ + + + + CGLCG+YNG +G EFGN +
Sbjct: 142 GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNMQKIN 200
Query: 88 VPDSPCLPPTPCPPGSEDCIPS----HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLV 143
PD C P E+ P+ H+ E E+ E F + C LV
Sbjct: 201 QPDVVCEDP------EEEVAPASCSEHRA--ECERLLTAEAF-----------ADCQDLV 241
Query: 144 DPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF-----CPMECP 198
+ L+ C D C G + +CS + + C AGG WRT T CP
Sbjct: 242 PLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCP 301
Query: 199 PNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSG 236
N Y C CS L C++ +GC C G
Sbjct: 302 GNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEG 339
Score = 60.8 bits (146), Expect = 3e-09
Identities = 56/206 (27%), Positives = 81/206 (39%), Gaps = 19/206 (9%)
Query: 351 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 401
P TC G Q V + + + CW W GDPHY +FDG + +QG C YVL
Sbjct: 1912 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 1970
Query: 402 GCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 460
P V G+ N P VR T L + + ++ +V+VN
Sbjct: 1971 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAV 2029
Query: 461 ALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNM 517
ALP G G + + + + G+ VSY+ V LP YH G CG
Sbjct: 2030 ALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTC 2085
Query: 518 DRNPNNDQVFPNGTLAPSIPIWGGSW 543
++D + P+G + + W
Sbjct: 2086 TNTTSDDCILPSGEIVSNCEAAADQW 2111
Score = 45.1 bits (105), Expect = 2e-04
Identities = 51/218 (23%), Positives = 86/218 (39%), Gaps = 16/218 (7%)
Query: 372 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 431
C WG+ HY +FDG F F G C+Y A + C G F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFA-SDCRG----SYKEFAVHLKRGPGQAEAPAGV 91
Query: 432 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVTQGASKALLVADFGLQ 489
+ ++I D I R VL VS + + + + + + GL
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
Query: 490 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 549
+ ++ + + L + + CGLCG+ + + + +G L + +G + D
Sbjct: 145 LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
Query: 550 PLCWDECRGSCP-TCPEDRLEQYEGLDEGSLSDHKDKI 586
+C D P +C E R E L + +D +D +
Sbjct: 204 VVCEDPEEEVAPASCSEHRAECERLLTAEAFADCQDLV 241
Score = 33.1 bits (74), Expect = 0.74
Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 10/131 (7%)
Query: 433 VVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA---DFGLQ 489
VV +A N+ + K + G V +N + LP A SV + +S ++V+ LQ
Sbjct: 348 VVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTAS--FSVFRPSSYHIMVSMAIGVRLQ 404
Query: 490 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG-- 547
V ++ VTL + G V GLCGN + +D +G + + + +W+A
Sbjct: 405 VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSC 464
Query: 548 WDPLCW--DEC 556
D L W D C
Sbjct: 465 HDKLDWLDDPC 475
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 166 bits (420), Expect = 6e-41
Identities = 143/532 (26%), Positives = 201/532 (37%), Gaps = 53/532 (9%)
Query: 41 VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCP 100
+T+ + Q+ GLCG + + +DDF P G + F + ++ CP
Sbjct: 683 ITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGR-------CP 735
Query: 101 PGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG 160
SED C ++ E C +L S CH+LVD + C+ +C
Sbjct: 736 --SEDSALLSPCTTHSQRHAFAEAACAILHSSV--FQECHRLVDKEPFYLRCLAAVCGCD 791
Query: 161 GNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAP 220
LC + AY C A G PWR +T CP+ CP Y CA C C P
Sbjct: 792 PGSDCLCPVLSAYARRC-AQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---P 847
Query: 221 PQCQD--GCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCH 277
C + C GC C G L++ + CVP C C Y P + + R C C
Sbjct: 848 EDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNR--CICQ 905
Query: 278 AGKVVVCQEHSCKPGQVCQ------PSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQP 331
+ C C C P +L+C + S D + G
Sbjct: 906 ERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTD---GCVCPPGTV 962
Query: 332 L---KVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNY--------EATCWLWGDPHY 380
L + + P L P G P T +E VC C G PHY
Sbjct: 963 LLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHY 1022
Query: 381 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALG 440
+FDG F + G C Y+L GL FTV+ +N G ++ + + V G
Sbjct: 1023 VTFDGLAFTYPGACEYLLVR------EASGL--FTVSAQNLPCGASGLTCTKALAVRLEG 1074
Query: 441 TNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDV 500
T + + + V VNGV P +S+ + LL GL + +D RV V
Sbjct: 1075 TVVHMLRGRA--VTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLV 1132
Query: 501 TLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLC 552
L + G V GLCG+ D + +ND G L P+ + SWR PLC
Sbjct: 1133 QLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL---SPLC 1181
Score = 137 bits (345), Expect = 3e-32
Identities = 85/275 (30%), Positives = 115/275 (41%), Gaps = 20/275 (7%)
Query: 18 GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNA 77
G +V+ G+ V D + ++V + Q GLCG YNG P+DDF +P G A A
Sbjct: 286 GDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLA 345
Query: 78 NEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEK---KYQKEEFCGLLSSPTG 134
FGNSW +S CL G C P ++E + + ++ C L G
Sbjct: 346 ATFGNSWRLPGSESGCLDAVEVAQG---CDPLGLIDADVEPGHLRAEAQDVCHQLLE--G 400
Query: 135 PLSSCHKLVDPQGPLKDCIFDLCLGG-------GNLSILCSNIHAYVSACQAAGGHVEPW 187
P CH V P + C+F C G G +C+ +YV AC H+ W
Sbjct: 401 PFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-W 459
Query: 188 RTETFCPMECPPNSHYELCADTCSLGCSALSAPPQ--CQDGCAEGCQCDSGFLYNGQACV 245
R FC CP Y C C C A+ + C++ C GC+C G +NG CV
Sbjct: 460 RKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCV 519
Query: 246 PIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280
P C CY+ Y P TV C C G+
Sbjct: 520 PAAHCPCYYCRQRYVPGDTV--RQLCNPCVCRDGR 552
Score = 118 bits (295), Expect = 2e-26
Identities = 109/390 (27%), Positives = 146/390 (37%), Gaps = 45/390 (11%)
Query: 4 PVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPK 63
P V + + G +++ T GL + +D V V + + ++ GLCG+++GD
Sbjct: 1095 PKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDAS 1154
Query: 64 DDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKE 123
+D + G A +SW L P PG +P H C +
Sbjct: 1155 NDLRSRQGVLEPTAELAAHSWR--------LSPLCPEPGD---LP-HPCTMNTHRAGWAR 1202
Query: 124 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNLSILCSNIHAYVSACQAAG 181
CG L P L CH V PQ + C++D C GG+ LCS I Y C G
Sbjct: 1203 ARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHG 1260
Query: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP--QCQ-DGCAEGCQCDSGFL 238
HV WR++ C ++C YE C TC C P CQ C EGC C G L
Sbjct: 1261 HHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTL 1319
Query: 239 YNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK-------------VVVCQ 285
+G AC+ C C G P +VL +C CTC G+ V C
Sbjct: 1320 LHGGACLEPASCPC-EWGRNSFPPGSVLQKDC-GNCTCQEGQWHCGGDGGHCEELVPACA 1377
Query: 286 EHS--CKPGQVCQPSGGIL----SCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLL 339
E C+ C P G + C A G EG +G L + L
Sbjct: 1378 EGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPGCG-EGQMTCSSGHCLPLALLCD 1436
Query: 340 SPDPCHGVTCRPQETCKE---QGGQGVCLP 366
D C T P C + G CLP
Sbjct: 1437 RQDDCGDGTDEPSYPCPQGLLACADGRCLP 1466
Score = 79.0 bits (193), Expect = 1e-14
Identities = 100/381 (26%), Positives = 131/381 (34%), Gaps = 96/381 (25%)
Query: 84 WEEV-VPDSPCLPPTPCPPGS--ED--CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 138
W+ V PC P CPPG +D C+P C CGL S+ ++
Sbjct: 4690 WDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCR------------CGLPSA-----NA 4732
Query: 139 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYV-------SACQA--AGGHVEPWRT 189
+L Q DC C+ N S++C + V S+C A GG +E RT
Sbjct: 4733 SWELAPAQAVQLDCQNCTCV---NESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRT 4789
Query: 190 -------------ETF---------CPMECPPNSHYELCADTCSLGCSALSAPPQC-QDG 226
+T CP ECPP CA +C C L C Q+
Sbjct: 4790 CEGGPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP 4848
Query: 227 CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE------------PEQTVLIDNCRQQC 274
C GC C G L + CVP C C + + + P TVL NC +C
Sbjct: 4849 CQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNC-TRC 4907
Query: 275 TCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKV 334
CH G SC P G V L QT +++ N
Sbjct: 4908 VCHGG------AFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSN------ 4955
Query: 335 LLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTC 394
S G C+P + G C+P CW G PH ++Q C
Sbjct: 4956 ----CSSARASGCVCQPGHF---RSQAGPCVPEDHCECWHLGRPHLPG-----SEWQEAC 5003
Query: 395 NYVLATTGCPGVSTQGLTPFT 415
L +G P V TQ +P T
Sbjct: 5004 ESCLCLSGRP-VCTQHCSPLT 5023
Score = 72.0 bits (175), Expect = 1e-12
Identities = 65/241 (26%), Positives = 83/241 (34%), Gaps = 36/241 (14%)
Query: 82 NSWEEVVPDSPCLPPTPCPPGSEDCIPSH----------KCPPELEKKYQKEEFC----- 126
+ W E P PCLPP+ P S + H P L + + C
Sbjct: 4526 SEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPAT 4585
Query: 127 -----GLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSN---IHAYVSACQ 178
G T PLS DP C + L + CS + +
Sbjct: 4586 GRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEAL 4645
Query: 179 AAGGHVEPWRTETFCPMECPPNSHYEL-----CADTCSLGCSALSAPPQCQDG-CAEGCQ 232
GG EPW E+ CP + CA+ C C+ L QC G C GC+
Sbjct: 4646 CGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCR 4705
Query: 233 CDSGFLYNGQACVPIQQCGC----YHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHS 288
C G L CVPI C C + P Q V +D C Q CTC + +VC
Sbjct: 4706 CPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLD-C-QNCTC-VNESLVCPHQE 4762
Query: 289 C 289
C
Sbjct: 4763 C 4763
Score = 68.2 bits (165), Expect = 2e-11
Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 3/100 (3%)
Query: 194 PMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCY 253
P CP + + CA + C+ LSAP C GC C SG L CVP Q C C
Sbjct: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 254 HNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQ 293
H G Y P TV + C + C+C +G + C C G+
Sbjct: 3146 HEGHLYPPGSTV-VRPC-ENCSCVSGLIANCSSWPCAEGE 3183
Score = 68.2 bits (165), Expect = 2e-11
Identities = 66/243 (27%), Positives = 86/243 (35%), Gaps = 41/243 (16%)
Query: 71 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCP-------PELEKKYQKE 123
G AGN SW P PC C G + + +++ P P + YQ+
Sbjct: 3941 GCGAGNC-----SWTSWAPWEPC--SRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQER 3993
Query: 124 EFCGLLSSPT-------GPLSSCHKLVDPQGPLKDCIFDLCLGGGNL-SILCSNIHAYVS 175
FC L + P P S C + C GG +L S CS+ +
Sbjct: 3994 RFCNLRACPVPGGWSRWSPWSWCDRS--------------CGGGQSLRSRSCSSPPSKNG 4039
Query: 176 ACQAAGG-HVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--CAEGCQ 232
AG H C CP CA+ C CS L CQD C +GC+
Sbjct: 4040 GAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR 4099
Query: 233 CDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPG 292
C G L CVPI C C + + D C C+C AG+ + C C P
Sbjct: 4100 CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDAC-NNCSCQAGQ-LSCTAQPCPPP 4157
Query: 293 QVC 295
C
Sbjct: 4158 THC 4160
Score = 63.2 bits (152), Expect = 7e-10
Identities = 53/185 (28%), Positives = 74/185 (40%), Gaps = 14/185 (7%)
Query: 370 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 429
ATC W HY +FDGR + F G C Y+LA + LTP P
Sbjct: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVH-LTP--------GDRCPQPG 243
Query: 430 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 489
+ + VT+ I + G V V G L S +S+ +L G+
Sbjct: 244 HCQRVTMGPEEVLI-----QAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVV 298
Query: 490 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 549
V D + +++ G GLCG + P +D + P G LA +G SWR PG +
Sbjct: 299 VRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSE 358
Query: 550 PLCWD 554
C D
Sbjct: 359 SGCLD 363
Score = 59.3 bits (142), Expect = 1e-08
Identities = 51/206 (24%), Positives = 71/206 (34%), Gaps = 13/206 (6%)
Query: 167 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHY---ELC---ADTCSLGCSALSAP 220
CS++ + C T+ C +CP N + E C C C
Sbjct: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
Query: 221 PQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280
+C CA GC C G + +C+P QC C +G Y +D+C CTC +GK
Sbjct: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSC-NNCTCVSGK 2974
Query: 281 VVVCQEHSCKPGQVCQP--SGGILSCVTKVTLRSLAQTGVDVEGA--AILYNGQPLKVLL 336
+ C C P + SC V +R + G A G ++
Sbjct: 2975 -MACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEF 3033
Query: 337 PLLSPDPCHGVTCRPQETCKEQGGQG 362
L P P G P C G G
Sbjct: 3034 CSLRPCPGPGGEWGPWSPCSVPCGGG 3059
Score = 57.4 bits (137), Expect = 4e-08
Identities = 42/148 (28%), Positives = 55/148 (37%), Gaps = 34/148 (22%)
Query: 152 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCS 211
C C GG + C YVSA G V P CPP+
Sbjct: 2604 CGLQPCSGGTD----CELGRVYVSADLCQKGLVPP----------CPPS----------- 2638
Query: 212 LGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCR 271
C A C C EGC+C G L + C+P+ +C C P + L+ NC
Sbjct: 2639 --CLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNC- 2695
Query: 272 QQCTCHAGKVVVCQEHSCKPGQVCQPSG 299
QC C G+++ C+PG P G
Sbjct: 2696 SQCVCEKGELL------CQPGGCPLPCG 2717
Score = 55.8 bits (133), Expect = 1e-07
Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 177 CQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD--GCAEGCQCD 234
C GH P C P + C C+ C+ + CQD C GC C
Sbjct: 4403 CTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCP 4462
Query: 235 SGFLYNGQACVPIQQCGCYHN-----GVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSC 289
G L C+P ++C C+H G+ P + + C+ +C C G+ + C C
Sbjct: 4463 KGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQL-GCK-ECECRRGE-LHCTSQGC 4519
Query: 290 K 290
+
Sbjct: 4520 Q 4520
Score = 52.8 bits (125), Expect = 9e-07
Identities = 47/166 (28%), Positives = 56/166 (33%), Gaps = 28/166 (16%)
Query: 145 PQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVE--PWRTETFCPMECPPNSH 202
P GP C D+CLG + S CS G H + P + + +C
Sbjct: 3477 PWGPWSPC--DMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQS 3534
Query: 203 YELCADTCSLGCSALSAPPQCQDG---CAEGCQCDSGFLYNGQACVPIQQCGC-YHNGVY 258
C C C LS CQ G C C C G L CVP C C Y G
Sbjct: 3535 LHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAM 3594
Query: 259 YEPEQ------------------TVLIDNCRQQCTCHAGKVVVCQE 286
PE V+ C CTC AG ++ CQE
Sbjct: 3595 GIPENQSRSAGSRFSSWESLEPGEVVTGPC-DNCTCVAG-ILQCQE 3638
Score = 44.3 bits (103), Expect = 3e-04
Identities = 37/120 (30%), Positives = 51/120 (42%), Gaps = 15/120 (12%)
Query: 177 CQAAGGHVEPWRTETFCPMECPPNSH------YELCADTCSLGCSALSA----PPQCQDG 226
C A G + R CP + PN+ ++ CA C L C +S PP G
Sbjct: 1786 CAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCG 1844
Query: 227 CAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQ 285
+ GC C G + + CV +QC C +G Y P Q + D C Q C C G+ C+
Sbjct: 1845 -SPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD-C-QLCICQDGRPRRCR 1901
Score = 43.9 bits (102), Expect = 4e-04
Identities = 52/200 (26%), Positives = 68/200 (34%), Gaps = 48/200 (24%)
Query: 93 CLPPTPCPPG--SED--CIPSHKCP----------PELEKKYQKEEFCGLLSSP-----T 133
C P CP G S+D C+P C PE + + F S T
Sbjct: 3562 CQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVT 3621
Query: 134 GPLSSCHKLV------------DPQ-----GPLKDCIFDLCLGGGNL-SILCSNIHAYVS 175
GP +C + DP GP +DC C GG L S C+
Sbjct: 3622 GPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVS-CGGGEQLRSRRCAR-----P 3675
Query: 176 ACQAAGGHVEPWRTETFCPMECPPNSHYELC--ADTCSLGCSALSAPPQC-QDGCAEGCQ 232
C T+ CP Y C + C C+ ++ C +GC EGC
Sbjct: 3676 PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCH 3735
Query: 233 CDSGFLYNGQACVPIQQCGC 252
C G + ACV Q+C C
Sbjct: 3736 CPEGTFQHRLACV--QECPC 3753
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 160 bits (405), Expect = 3e-39
Identities = 156/590 (26%), Positives = 228/590 (38%), Gaps = 107/590 (18%)
Query: 21 VVIETDFGLRVAYDLVYYVRV--TVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNAN 78
++ +T GL++ LV +++ + Q CGLCGN+N DDF+ +G A
Sbjct: 535 IIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAA 594
Query: 79 EFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 138
F N+++ CP C +E + + +C L+ GP
Sbjct: 595 AFFNTFKT---------QAACPNIRNSF--EDPCSLSVENEKYAQHWCSQLTDADGPFGR 643
Query: 139 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFC--PM- 195
CH V P +C+FD C + LC+ + +YV AC A G + WR + C PM
Sbjct: 644 CHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWR-DGVCTKPMT 702
Query: 196 ECPPNSHYELCADTCSLGCSALS-APPQCQDGC--AEGCQCDSG-FLYNGQACVPIQQCG 251
CP + Y TC C +LS C G +GC C G FL + CV C
Sbjct: 703 TCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCP 762
Query: 252 CYHNGVYYEPEQTVLIDNCRQQCTCHAGKV------------------------------ 281
CYH G ++V + CTC GK+
Sbjct: 763 CYHRGSMIPNGESV--HDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTG 820
Query: 282 -----------VVCQEHSCKPGQVCQPSG----GILSCVTKVTLRSLAQTGVDVEGAAIL 326
+ C C PG VC P G G C+T A+ V A
Sbjct: 821 AGCQKSCHTLDMTCYSPQCVPGCVC-PDGLVADGEGGCIT-------AEDCPCVHNEASY 872
Query: 327 YNGQPLKVLLPLLSPDPCHGVTCRPQE-TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDG 385
GQ ++V C+ TC + C + CL ATC ++GD HY +FDG
Sbjct: 873 RAGQTIRV--------GCNTCTCDSRMWRCTDD----PCL----ATCAVYGDGHYLTFDG 916
Query: 386 RKFDFQGTCNYVLATTGCPGV-STQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNIS 444
+ + F G C Y L C G STQ F V T+N G + + + + G +
Sbjct: 917 QSYSFNGDCEYTLVQNHCGGKDSTQ--DSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
Query: 445 IHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPS 504
+ GKV V G + V ++ Q ++ D GL + +D + + L
Sbjct: 975 LSH---GKVEVIGTDESQEVP-----YTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSP 1026
Query: 505 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWD 554
+ G VCGLCGN D ND + ++ + +G SW+ P C D
Sbjct: 1027 EFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPD 1073
Score = 125 bits (314), Expect = 1e-28
Identities = 98/304 (32%), Positives = 128/304 (42%), Gaps = 29/304 (9%)
Query: 4 PVVLANGQ--IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGD 61
PV+L Q + Q S +E GL + ++ + + + Y + CGLCG++NG
Sbjct: 158 PVLLPFSQSGVLIQQSSSYTKVEARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGM 217
Query: 62 PKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
P + ++ EFGN + P C P P PP +C EL
Sbjct: 218 PVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDPVPEPP--RNCSTGFGICEEL----- 269
Query: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGN--LSILCSNIHAYVSACQA 179
G L S C LVD L+ C DLC LS +C + Y C
Sbjct: 270 ---LHGQL------FSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTH 320
Query: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 239
AGG + WR FCP +CP N Y C C+ CS C+D C GC C G +
Sbjct: 321 AGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTVL 380
Query: 240 N--GQ-ACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQ 296
+ GQ CVP+ +C C +NG Y P T D C CTC G+ CQE C PG C
Sbjct: 381 DDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-C-TNCTCSGGR-WSCQEVPC-PG-TCS 435
Query: 297 PSGG 300
GG
Sbjct: 436 VLGG 439
Score = 102 bits (255), Expect = 8e-22
Identities = 78/280 (27%), Positives = 119/280 (42%), Gaps = 34/280 (12%)
Query: 16 QHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAG 75
Q G +V++TD GL + +D + + + + ++CGLCGN++ +DF + S G
Sbjct: 997 QMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVG 1056
Query: 76 NANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGP 135
+ EFGNSW+ L P+ CP + P C +K ++ C +L PT
Sbjct: 1057 DVLEFGNSWK--------LSPS-CP---DALAPKDPCTANPFRKSWAQKQCSILHGPT-- 1102
Query: 136 LSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFC 193
++CH V+P + C+ D C GG+ C+ + AY AC G V WRT + C
Sbjct: 1103 FAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVS-WRTPSIC 1161
Query: 194 PMECP---PNSHYELCADTCSLGCSALSAPPQCQ--------DGCAEGCQCDSG-FLYNG 241
P+ C P E C + C P+ +GC C ++ F +
Sbjct: 1162 PLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDK 1221
Query: 242 QACV-----PIQQCGCYHNGVYYEPEQTVLIDNCRQQCTC 276
CV P C+ +G Y P V D Q C C
Sbjct: 1222 MQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLC 1261
Score = 55.8 bits (133), Expect = 1e-07
Identities = 46/160 (28%), Positives = 71/160 (44%), Gaps = 12/160 (7%)
Query: 372 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 431
C WG HY +FDG F F G CNYV + C G + + ++Q P +S
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVF-SEHC-GAAYEDFN--IQLRRSQESAAPTLSR- 135
Query: 432 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 491
V + G I + K G V VNG LP S + + Q +S + A GL +
Sbjct: 136 --VLMKVDGVVIQLTK---GSVLVNGHPVLLPFS--QSGVLIQQSSSYTKVEARLGLVLM 188
Query: 492 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 531
++ + + + L + Y CGLCG+ + P ++ + T
Sbjct: 189 WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNT 228
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 160 bits (404), Expect = 4e-39
Identities = 137/553 (24%), Positives = 221/553 (39%), Gaps = 60/553 (10%)
Query: 23 IETDFGLRVAYDLVYYVR--VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 80
+ET F +++ +V ++ V++P N + GLCG+YN +DDF + F
Sbjct: 959 VETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAF 1018
Query: 81 GNSWEEVVPDSPCLPPTPCPPGS-EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139
NSWE + CP G+ CI +EK+ E CG+L +GPL+SC
Sbjct: 1019 ANSWEMM----------SCPKGNPSSCI-------SIEKEKFAERHCGILLDSSGPLASC 1061
Query: 140 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199
H +V+P+ ++C C + LC+ + YV AC ++ WRT C CP
Sbjct: 1062 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPS 1120
Query: 200 NSHYELCADTCSLGCSALSAPPQ---CQDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHN 255
++ C+ C +LS + +D +GC C N + CV QC CY N
Sbjct: 1121 GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIN 1180
Query: 256 GVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQ 315
+P + + ID+ +C C G +++CQ Q C + C R +
Sbjct: 1181 DEVMQPGKLIHIDD--NKCVCRDG-ILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNR 1237
Query: 316 TGVDVEGAAILYNGQPLK--VLLP----------LLSPDPC-----------HGVTCRPQ 352
T + P K P + P+ C VT
Sbjct: 1238 T-CSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGC 1296
Query: 353 ETCKEQGGQGVCLPN-YEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGL 411
C G C N + C ++G+ H +FDG+ + F G C Y C +
Sbjct: 1297 NECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN---- 1352
Query: 412 TPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 471
F + T++ ++ R + VA NI + + GKV + +
Sbjct: 1353 GTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVL---QDGKVTAVKSTESKKCELNANAY 1409
Query: 472 SVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 531
S+ +L G+ V +D N R+ V L +++G VCGLCGN + + +D +
Sbjct: 1410 SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSS 1469
Query: 532 LAPSIPIWGGSWR 544
+A +G SW+
Sbjct: 1470 VASGALEFGNSWK 1482
Score = 107 bits (268), Expect = 2e-23
Identities = 85/278 (30%), Positives = 118/278 (42%), Gaps = 32/278 (11%)
Query: 18 GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNA 77
G ++++ G+ V +D + V + N+ ++CGLCGN NGD KDDF S A A
Sbjct: 1415 GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGA 1474
Query: 78 NEFGNSWEEVVPDSPCLPPT-PCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPL 136
EFGNSW+ S + T PC D P C +K C +L T
Sbjct: 1475 LEFGNSWKTSQECSDTVAQTFPC-----DSNP--YCKAWAVRK------CEILRDST--F 1519
Query: 137 SSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 194
CH VDP CI + C G C+ + Y AC A G V WR CP
Sbjct: 1520 RDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCP 1578
Query: 195 MECPPNS-------HYELCADTCSLGCSALSAPPQCQ---DGCAEGCQCDSGFL-YNGQA 243
+ C + HYE C + C + +GC C + +L N
Sbjct: 1579 VYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMK 1638
Query: 244 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKV 281
CV + +C C++N V P V+ DNC + C C AG++
Sbjct: 1639 CVSLSECSCFYNDVI--PAGGVIEDNCGRTCYCIAGQL 1674
Score = 55.8 bits (133), Expect = 1e-07
Identities = 53/188 (28%), Positives = 78/188 (41%), Gaps = 27/188 (14%)
Query: 124 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG-G 182
E CG +++ LS+ +K++ CI + C S C C + G G
Sbjct: 698 EKCGKVAA----LSNDYKMI--------CIDEYCQTRDKTST-CDTYSELSRLCASDGPG 744
Query: 183 HVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 239
E WR+++ E CP Y+ C + CS ++ P C GC C G+L
Sbjct: 745 TFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVA--PFQDSECVSGCTCPEGYLL 802
Query: 240 NG----QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVC 295
+ CV +C C +G Y+P + V C QCTC K C E C PG+ C
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAK-WSCTEALC-PGR-C 858
Query: 296 QPSGGILS 303
+ G L+
Sbjct: 859 KVEGSSLT 866
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 160 bits (404), Expect = 4e-39
Identities = 137/553 (24%), Positives = 221/553 (39%), Gaps = 60/553 (10%)
Query: 23 IETDFGLRVAYDLVYYVR--VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 80
+ET F +++ +V ++ V++P N + GLCG+YN +DDF + F
Sbjct: 959 VETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAF 1018
Query: 81 GNSWEEVVPDSPCLPPTPCPPGS-EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139
NSWE + CP G+ CI +EK+ E CG+L +GPL+SC
Sbjct: 1019 ANSWEMM----------SCPKGNPSSCI-------SIEKEKFAERHCGILLDSSGPLASC 1061
Query: 140 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199
H +V+P+ ++C C + LC+ + YV AC ++ WRT C CP
Sbjct: 1062 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPS 1120
Query: 200 NSHYELCADTCSLGCSALSAPPQ---CQDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHN 255
++ C+ C +LS + +D +GC C N + CV QC CY N
Sbjct: 1121 GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIN 1180
Query: 256 GVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQ 315
+P + + ID+ +C C G +++CQ Q C + C R +
Sbjct: 1181 DEVMQPGKLIHIDD--NKCVCRDG-ILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNR 1237
Query: 316 TGVDVEGAAILYNGQPLK--VLLP----------LLSPDPC-----------HGVTCRPQ 352
T + P K P + P+ C VT
Sbjct: 1238 T-CSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGC 1296
Query: 353 ETCKEQGGQGVCLPN-YEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGL 411
C G C N + C ++G+ H +FDG+ + F G C Y C +
Sbjct: 1297 NECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN---- 1352
Query: 412 TPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 471
F + T++ ++ R + VA NI + + GKV + +
Sbjct: 1353 GTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVL---QDGKVTAVKSTESKKCELNANAY 1409
Query: 472 SVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 531
S+ +L G+ V +D N R+ V L +++G VCGLCGN + + +D +
Sbjct: 1410 SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSS 1469
Query: 532 LAPSIPIWGGSWR 544
+A +G SW+
Sbjct: 1470 VASGALEFGNSWK 1482
Score = 107 bits (268), Expect = 2e-23
Identities = 85/278 (30%), Positives = 118/278 (42%), Gaps = 32/278 (11%)
Query: 18 GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNA 77
G ++++ G+ V +D + V + N+ ++CGLCGN NGD KDDF S A A
Sbjct: 1415 GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGA 1474
Query: 78 NEFGNSWEEVVPDSPCLPPT-PCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPL 136
EFGNSW+ S + T PC D P C +K C +L T
Sbjct: 1475 LEFGNSWKTSQECSDTVAQTFPC-----DSNP--YCKAWAVRK------CEILRDST--F 1519
Query: 137 SSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 194
CH VDP CI + C G C+ + Y AC A G V WR CP
Sbjct: 1520 RDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCP 1578
Query: 195 MECPPNS-------HYELCADTCSLGCSALSAPPQCQ---DGCAEGCQCDSGFL-YNGQA 243
+ C + HYE C + C + +GC C + +L N
Sbjct: 1579 VYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMK 1638
Query: 244 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKV 281
CV + +C C++N V P V+ DNC + C C AG++
Sbjct: 1639 CVSLSECSCFYNDVI--PAGGVIEDNCGRTCYCIAGQL 1674
Score = 55.1 bits (131), Expect = 2e-07
Identities = 53/188 (28%), Positives = 79/188 (42%), Gaps = 27/188 (14%)
Query: 124 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG-G 182
E CG +++ LS+ +K++ CI + C S C C + G G
Sbjct: 698 EKCGKVAA----LSNDYKMI--------CIDEYCQTRDKTST-CDTYSELSRLCASDGPG 744
Query: 183 HVEPWRTET--FCPME-CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 239
E WR+++ C + CP Y+ C + CS ++ P C GC C G+L
Sbjct: 745 TFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVA--PFQDSECVSGCTCPEGYLL 802
Query: 240 NG----QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVC 295
+ CV +C C +G Y+P + V C QCTC K C E C PG+ C
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAK-WSCTEALC-PGR-C 858
Query: 296 QPSGGILS 303
+ G L+
Sbjct: 859 KVEGSSLT 866
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 151 bits (382), Expect = 1e-36
Identities = 148/589 (25%), Positives = 227/589 (38%), Gaps = 91/589 (15%)
Query: 16 QHGSDVVIETDFGLRVAYDL--VYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQ 73
Q + + + T FGL + L ++ VTV + Q GLCGN+NGD DDF G
Sbjct: 492 QTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIA 551
Query: 74 AGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPT 133
G A+ F +SW CP E + C K E C +L
Sbjct: 552 EGTASLFVDSWRA----------GNCPAALER--ETDPCSMSQLNKVCAETHCSMLLRTG 599
Query: 134 GPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF- 192
CH V+P K C++ C +C+ + YV AC G + WR+
Sbjct: 600 TVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDN 659
Query: 193 CPMECPPNSHYELCADTCSLGCSALS-APPQCQDGCA--EGCQCDSGFLYNGQA-CVPIQ 248
C + C N+ + + C C +LS +C +GC C G N + CV
Sbjct: 660 CTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKA 719
Query: 249 QCGCYHNGV-YYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTK 307
QC C G + EQ+ +I+ C C G++ SC +P + SC
Sbjct: 720 QCPCILEGYKFILAEQSTVINGIT--CHCINGRL------SCPQ----RPQMFLASCQAP 767
Query: 308 VTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKE---QGGQGVC 364
T +S +Q+ + GAA Q L + C C P C E + G C
Sbjct: 768 KTFKSCSQSSENKFGAACAPTCQMLATGVA------CVPTKCEPGCVCAEGLYENADGQC 821
Query: 365 LPNYE---------------------------------------ATCWLWGDPHYHSFDG 385
+P E +TC L+G+ H +FDG
Sbjct: 822 VPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDG 881
Query: 386 RKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISI 445
++F F G C Y+LAT C GV+ T F + T+N GN V+ R + + G ++ +
Sbjct: 882 QRFVFDGNCEYILATDVC-GVNDSQPT-FKILTENVICGNSGVTCSRAIKIFLGGLSVVL 939
Query: 446 HKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSS 505
V G + + V G +S+ S + + L + ++ + + + + +
Sbjct: 940 AD---RNYTVTGEEPHVQLGVTPGALSLVVDIS---IPGRYNLTLIWNRHMTILIRIARA 993
Query: 506 YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWD 554
+CGLCGN + N +D + +A S SW+ PLC D
Sbjct: 994 SQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---SPLCGD 1039
Score = 91.7 bits (226), Expect = 2e-18
Identities = 80/287 (27%), Positives = 112/287 (39%), Gaps = 33/287 (11%)
Query: 21 VVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 80
V + + L V + ++ V V Y QMCGLCGN++G ++F G ++F
Sbjct: 142 VAKQLELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKF 200
Query: 81 GNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCH 140
+ P C +D +H ++ Q C L + P S
Sbjct: 201 AALQKLDDPGEICT--------FQDIPSTHV------RQAQHARICTQLLTLVAPECSVS 246
Query: 141 KLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPM-EC 197
K + + C D+ G + C+ + Y C G V WR+ C + +C
Sbjct: 247 K----EPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQC 302
Query: 198 PPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGF----LYNGQACVPIQQCGCY 253
P N Y+ C C CS + C C GC C G L N CVP+ QC C
Sbjct: 303 PANQVYQECGSACVKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCV 360
Query: 254 HNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
+G Y P + V I C Q C C G+ VC E C PG C GG
Sbjct: 361 LHGAMYAPGE-VTIAAC-QTCRCTLGR-WVCTERPC-PGH-CSLEGG 402
Score = 78.6 bits (192), Expect = 2e-14
Identities = 64/245 (26%), Positives = 99/245 (40%), Gaps = 34/245 (13%)
Query: 20 DVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANE 79
D+ I + L + ++ + + + +CGLCGN+NG+ KDDF+ + A + E
Sbjct: 967 DISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELE 1026
Query: 80 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139
NSW+E P + + C ++ E C +++S T ++C
Sbjct: 1027 LVNSWKE------------SPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQT--FATC 1072
Query: 140 HKLVDPQGPLKDCIFDL--CLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
H V + C+ D C GG+ LC + AY AC G V+ WRT FCP+ C
Sbjct: 1073 HSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVD-WRTPAFCPIYC 1131
Query: 198 P-PNSH-------YELCADT--------CSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
N+H Y+ + C S P +GC C D F +
Sbjct: 1132 GFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGC-YNCSQDEYFDHEE 1190
Query: 242 QACVP 246
CVP
Sbjct: 1191 GVCVP 1195
Score = 64.7 bits (156), Expect = 2e-10
Identities = 49/161 (30%), Positives = 73/161 (45%), Gaps = 15/161 (9%)
Query: 372 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 431
C WG H+ +FD +DF GTCNY+ A T F+V Q R P S
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAAT-----CKDAFPTFSV----QLRRGPDGSIS 95
Query: 432 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 491
R+ + LG ++ + I V+ GV+ +LP + ++G G S L+ L++
Sbjct: 96 RI--IVELGASVVTVSEAIISVKDIGVI-SLPYT-SNGLQITPFGQSVRLVAKQLELELE 151
Query: 492 YDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 530
W + + V + Y G +CGLCGN D N+ V G
Sbjct: 152 VVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG 192
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 147 bits (371), Expect = 3e-35
Identities = 143/565 (25%), Positives = 215/565 (38%), Gaps = 79/565 (13%)
Query: 23 IETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANE 79
+ T+ G+RV YD L Y++V + + GLCG +NG+ +DDF P G
Sbjct: 546 VRTNVGVRVLYDREGLRLYLQVDQ--RWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 603
Query: 80 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139
FGNSW+ + SP + +P P C L+ + C +L+ + C
Sbjct: 604 FGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM--FAPC 651
Query: 140 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199
+ P + C D C G LC+ + Y C+ G V+ C + C
Sbjct: 652 SAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 709
Query: 200 NSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA--CVPIQ 248
+ Y C C C L++P C +D C EGC C + QA CVP
Sbjct: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
Query: 249 QCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEH----SCKPGQVCQPSGGI--- 301
QC C+ GV Y P + + C C G V+ C +C GQV +
Sbjct: 770 QCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCSDLHTD 826
Query: 302 ------LSCVTKVTLRSLAQTGVDVEGAA----ILYNGQPLKVLLPLLSPDPCHG----- 346
+C ++ S++ G + G A +L +G LP P G
Sbjct: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD--ACFLPEECPCTWKGKEYFP 884
Query: 347 --VTCRPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 403
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 885 GDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL----- 939
Query: 404 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 463
V + F+V +N N + + + +++ +G ++ + D+ G P
Sbjct: 940 --VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPSP 988
Query: 464 VSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 520
S D + V + F + + +D V V + G + GLCGN D
Sbjct: 989 ESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLK 1048
Query: 521 PNNDQVFPNGTLAPSIPIWGGSWRA 545
N+ P + +G SW A
Sbjct: 1049 TINEMRTPENLELTNPQEFGSSWAA 1073
Score = 129 bits (323), Expect = 1e-29
Identities = 84/285 (29%), Positives = 128/285 (44%), Gaps = 20/285 (7%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
++LP V+ G R Q V++ +A+D V + + GLCGN N
Sbjct: 160 VQLPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNA 217
Query: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT---PCPPGSEDCIPSHKCPPELE 117
DPKDD +G + EF +SW+E P+ P P T P PP C+ + P ++
Sbjct: 218 DPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPP----CLQQN--PGTMQ 271
Query: 118 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 177
Y++ C L P P +CH V P C DLC G+++ C + Y AC
Sbjct: 272 GVYEQ---CEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARAC 326
Query: 178 QAAGGHVEPWRTE-TFCPMECPPNSH-YELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 235
AG ++ WRT+ C + C + Y C C C ++ + C +GC C +
Sbjct: 327 AQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPN 386
Query: 236 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280
G ++ CV +C C +G Y P +V+ ++C CTC +GK
Sbjct: 387 GLIFEDGGCVAPAECPCEFHGTLY-PPGSVVKEDC-NTCTCTSGK 429
Score = 67.0 bits (162), Expect = 5e-11
Identities = 87/344 (25%), Positives = 123/344 (35%), Gaps = 72/344 (20%)
Query: 53 GLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDCIPS 109
GLCG +GD +D +GS G A + F +SW+ VP S L D +
Sbjct: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDSCAT 2229
Query: 110 HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSN 169
C P L ++S+ T S+CH+ V P+ + I D + C
Sbjct: 2230 TDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQPCVA 2273
Query: 170 IHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--- 226
+ YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2274 LTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDGILG 2325
Query: 227 ---------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLIDNC 270
EGC C G + + C+P +C C + GV E + L C
Sbjct: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 271 RQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQ 330
+ Q C A +V + C PS SC+ + L T + Q
Sbjct: 2386 QHQ--CQAPDTIVPVDLGC-------PSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2436
Query: 331 PLKVLLPLLSPDPCHGV--TCRPQETCKEQGGQGVCLPNYEATC 372
L C G+ TCRP + C P+Y C
Sbjct: 2437 TL-----------CEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 66.6 bits (161), Expect = 6e-11
Identities = 47/162 (29%), Positives = 70/162 (43%), Gaps = 20/162 (12%)
Query: 39 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 98
V V + Q+ GLCGN++ ++ + P + N EFG+SW V
Sbjct: 1026 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV----------E 1075
Query: 99 CPPGSEDCIPSHKCP-PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL- 156
CP + P C L + + K+E C +L S CH +VD +C+ D
Sbjct: 1076 CP---DTLDPRDMCVLNPLREPFAKKE-CSILLSEV--FEICHPVVDVTWFYSNCLTDTC 1129
Query: 157 -CLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
C GG+ C+++ AY C G V+ WRT CP +C
Sbjct: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLCPYDC 1170
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 424
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW- 543
+++D V + + G GLCGN + +P +D V +G L + + SW
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 544 -RAPGWDP 550
+AP P
Sbjct: 243 EQAPNQPP 250
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 147 bits (371), Expect = 3e-35
Identities = 143/565 (25%), Positives = 215/565 (38%), Gaps = 79/565 (13%)
Query: 23 IETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANE 79
+ T+ G+RV YD L Y++V + + GLCG +NG+ +DDF P G
Sbjct: 618 VRTNVGVRVLYDREGLRLYLQVDQ--RWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 675
Query: 80 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139
FGNSW+ + SP + +P P C L+ + C +L+ + C
Sbjct: 676 FGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM--FAPC 723
Query: 140 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199
+ P + C D C G LC+ + Y C+ G V+ C + C
Sbjct: 724 SAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 781
Query: 200 NSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA--CVPIQ 248
+ Y C C C L++P C +D C EGC C + QA CVP
Sbjct: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841
Query: 249 QCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEH----SCKPGQVCQPSGGI--- 301
QC C+ GV Y P + + C C G V+ C +C GQV +
Sbjct: 842 QCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCSDLHTD 898
Query: 302 ------LSCVTKVTLRSLAQTGVDVEGAA----ILYNGQPLKVLLPLLSPDPCHG----- 346
+C ++ S++ G + G A +L +G LP P G
Sbjct: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD--ACFLPEECPCTWKGKEYFP 956
Query: 347 --VTCRPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 403
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 957 GDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL----- 1011
Query: 404 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 463
V + F+V +N N + + + +++ +G ++ + D+ G P
Sbjct: 1012 --VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPSP 1060
Query: 464 VSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 520
S D + V + F + + +D V V + G + GLCGN D
Sbjct: 1061 ESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLK 1120
Query: 521 PNNDQVFPNGTLAPSIPIWGGSWRA 545
N+ P + +G SW A
Sbjct: 1121 TINEMRTPENLELTNPQEFGSSWAA 1145
Score = 129 bits (323), Expect = 1e-29
Identities = 84/285 (29%), Positives = 128/285 (44%), Gaps = 20/285 (7%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
++LP V+ G R Q V++ +A+D V + + GLCGN N
Sbjct: 232 VQLPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNA 289
Query: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT---PCPPGSEDCIPSHKCPPELE 117
DPKDD +G + EF +SW+E P+ P P T P PP C+ + P ++
Sbjct: 290 DPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPP----CLQQN--PGTMQ 343
Query: 118 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 177
Y++ C L P P +CH V P C DLC G+++ C + Y AC
Sbjct: 344 GVYEQ---CEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARAC 398
Query: 178 QAAGGHVEPWRTE-TFCPMECPPNSH-YELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 235
AG ++ WRT+ C + C + Y C C C ++ + C +GC C +
Sbjct: 399 AQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPN 458
Query: 236 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280
G ++ CV +C C +G Y P +V+ ++C CTC +GK
Sbjct: 459 GLIFEDGGCVAPAECPCEFHGTLY-PPGSVVKEDC-NTCTCTSGK 501
Score = 67.0 bits (162), Expect = 5e-11
Identities = 87/344 (25%), Positives = 123/344 (35%), Gaps = 72/344 (20%)
Query: 53 GLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDCIPS 109
GLCG +GD +D +GS G A + F +SW+ VP S L D +
Sbjct: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDSCAT 2301
Query: 110 HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSN 169
C P L ++S+ T S+CH+ V P+ + I D + C
Sbjct: 2302 TDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQPCVA 2345
Query: 170 IHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--- 226
+ YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2346 LTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDGILG 2397
Query: 227 ---------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLIDNC 270
EGC C G + + C+P +C C + GV E + L C
Sbjct: 2398 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 271 RQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQ 330
+ Q C A +V + C PS SC+ + L T + Q
Sbjct: 2458 QHQ--CQAPDTIVPVDLGC-------PSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2508
Query: 331 PLKVLLPLLSPDPCHGV--TCRPQETCKEQGGQGVCLPNYEATC 372
L C G+ TCRP + C P+Y C
Sbjct: 2509 TL-----------CEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 66.6 bits (161), Expect = 6e-11
Identities = 47/162 (29%), Positives = 70/162 (43%), Gaps = 20/162 (12%)
Query: 39 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 98
V V + Q+ GLCGN++ ++ + P + N EFG+SW V
Sbjct: 1098 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV----------E 1147
Query: 99 CPPGSEDCIPSHKCP-PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL- 156
CP + P C L + + K+E C +L S CH +VD +C+ D
Sbjct: 1148 CP---DTLDPRDMCVLNPLREPFAKKE-CSILLSEV--FEICHPVVDVTWFYSNCLTDTC 1201
Query: 157 -CLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
C GG+ C+++ AY C G V+ WRT CP +C
Sbjct: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLCPYDC 1242
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 424
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW- 543
+++D V + + G GLCGN + +P +D V +G L + + SW
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 544 -RAPGWDP 550
+AP P
Sbjct: 315 EQAPNQPP 322
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 147 bits (371), Expect = 3e-35
Identities = 143/565 (25%), Positives = 215/565 (38%), Gaps = 79/565 (13%)
Query: 23 IETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANE 79
+ T+ G+RV YD L Y++V + + GLCG +NG+ +DDF P G
Sbjct: 546 VRTNVGVRVLYDREGLRLYLQVDQ--RWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 603
Query: 80 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139
FGNSW+ + SP + +P P C L+ + C +L+ + C
Sbjct: 604 FGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM--FAPC 651
Query: 140 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199
+ P + C D C G LC+ + Y C+ G V+ C + C
Sbjct: 652 SAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 709
Query: 200 NSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA--CVPIQ 248
+ Y C C C L++P C +D C EGC C + QA CVP
Sbjct: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
Query: 249 QCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEH----SCKPGQVCQPSGGI--- 301
QC C+ GV Y P + + C C G V+ C +C GQV +
Sbjct: 770 QCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCSDLHTD 826
Query: 302 ------LSCVTKVTLRSLAQTGVDVEGAA----ILYNGQPLKVLLPLLSPDPCHG----- 346
+C ++ S++ G + G A +L +G LP P G
Sbjct: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD--ACFLPEECPCTWKGKEYFP 884
Query: 347 --VTCRPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 403
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 885 GDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL----- 939
Query: 404 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 463
V + F+V +N N + + + +++ +G ++ + D+ G P
Sbjct: 940 --VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPSP 988
Query: 464 VSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 520
S D + V + F + + +D V V + G + GLCGN D
Sbjct: 989 ESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLK 1048
Query: 521 PNNDQVFPNGTLAPSIPIWGGSWRA 545
N+ P + +G SW A
Sbjct: 1049 TINEMRTPENLELTNPQEFGSSWAA 1073
Score = 129 bits (323), Expect = 1e-29
Identities = 84/285 (29%), Positives = 128/285 (44%), Gaps = 20/285 (7%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
++LP V+ G R Q V++ +A+D V + + GLCGN N
Sbjct: 160 VQLPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNA 217
Query: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT---PCPPGSEDCIPSHKCPPELE 117
DPKDD +G + EF +SW+E P+ P P T P PP C+ + P ++
Sbjct: 218 DPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPP----CLQQN--PGTMQ 271
Query: 118 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 177
Y++ C L P P +CH V P C DLC G+++ C + Y AC
Sbjct: 272 GVYEQ---CEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARAC 326
Query: 178 QAAGGHVEPWRTE-TFCPMECPPNSH-YELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 235
AG ++ WRT+ C + C + Y C C C ++ + C +GC C +
Sbjct: 327 AQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPN 386
Query: 236 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280
G ++ CV +C C +G Y P +V+ ++C CTC +GK
Sbjct: 387 GLIFEDGGCVAPAECPCEFHGTLY-PPGSVVKEDC-NTCTCTSGK 429
Score = 67.0 bits (162), Expect = 5e-11
Identities = 87/344 (25%), Positives = 123/344 (35%), Gaps = 72/344 (20%)
Query: 53 GLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDCIPS 109
GLCG +GD +D +GS G A + F +SW+ VP S L D +
Sbjct: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDSCAT 2229
Query: 110 HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSN 169
C P L ++S+ T S+CH+ V P+ + I D + C
Sbjct: 2230 TDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQPCVA 2273
Query: 170 IHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--- 226
+ YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2274 LTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDGILG 2325
Query: 227 ---------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLIDNC 270
EGC C G + + C+P +C C + GV E + L C
Sbjct: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 271 RQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQ 330
+ Q C A +V + C PS SC+ + L T + Q
Sbjct: 2386 QHQ--CQAPDTIVPVDLGC-------PSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2436
Query: 331 PLKVLLPLLSPDPCHGV--TCRPQETCKEQGGQGVCLPNYEATC 372
L C G+ TCRP + C P+Y C
Sbjct: 2437 TL-----------CEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 66.6 bits (161), Expect = 6e-11
Identities = 47/162 (29%), Positives = 70/162 (43%), Gaps = 20/162 (12%)
Query: 39 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 98
V V + Q+ GLCGN++ ++ + P + N EFG+SW V
Sbjct: 1026 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV----------E 1075
Query: 99 CPPGSEDCIPSHKCP-PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL- 156
CP + P C L + + K+E C +L S CH +VD +C+ D
Sbjct: 1076 CP---DTLDPRDMCVLNPLREPFAKKE-CSILLSEV--FEICHPVVDVTWFYSNCLTDTC 1129
Query: 157 -CLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
C GG+ C+++ AY C G V+ WRT CP +C
Sbjct: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLCPYDC 1170
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 424
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW- 543
+++D V + + G GLCGN + +P +D V +G L + + SW
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 544 -RAPGWDP 550
+AP P
Sbjct: 243 EQAPNQPP 250
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 147 bits (371), Expect = 3e-35
Identities = 143/565 (25%), Positives = 215/565 (38%), Gaps = 79/565 (13%)
Query: 23 IETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANE 79
+ T+ G+RV YD L Y++V + + GLCG +NG+ +DDF P G
Sbjct: 618 VRTNVGVRVLYDREGLRLYLQVDQ--RWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 675
Query: 80 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139
FGNSW+ + SP + +P P C L+ + C +L+ + C
Sbjct: 676 FGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM--FAPC 723
Query: 140 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199
+ P + C D C G LC+ + Y C+ G V+ C + C
Sbjct: 724 SAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 781
Query: 200 NSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA--CVPIQ 248
+ Y C C C L++P C +D C EGC C + QA CVP
Sbjct: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841
Query: 249 QCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEH----SCKPGQVCQPSGGI--- 301
QC C+ GV Y P + + C C G V+ C +C GQV +
Sbjct: 842 QCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCSDLHTD 898
Query: 302 ------LSCVTKVTLRSLAQTGVDVEGAA----ILYNGQPLKVLLPLLSPDPCHG----- 346
+C ++ S++ G + G A +L +G LP P G
Sbjct: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD--ACFLPEECPCTWKGKEYFP 956
Query: 347 --VTCRPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 403
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 957 GDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL----- 1011
Query: 404 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 463
V + F+V +N N + + + +++ +G ++ + D+ G P
Sbjct: 1012 --VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPSP 1060
Query: 464 VSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 520
S D + V + F + + +D V V + G + GLCGN D
Sbjct: 1061 ESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLK 1120
Query: 521 PNNDQVFPNGTLAPSIPIWGGSWRA 545
N+ P + +G SW A
Sbjct: 1121 TINEMRTPENLELTNPQEFGSSWAA 1145
Score = 129 bits (323), Expect = 1e-29
Identities = 84/285 (29%), Positives = 128/285 (44%), Gaps = 20/285 (7%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
++LP V+ G R Q V++ +A+D V + + GLCGN N
Sbjct: 232 VQLPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNA 289
Query: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT---PCPPGSEDCIPSHKCPPELE 117
DPKDD +G + EF +SW+E P+ P P T P PP C+ + P ++
Sbjct: 290 DPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPP----CLQQN--PGTMQ 343
Query: 118 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 177
Y++ C L P P +CH V P C DLC G+++ C + Y AC
Sbjct: 344 GVYEQ---CEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARAC 398
Query: 178 QAAGGHVEPWRTE-TFCPMECPPNSH-YELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 235
AG ++ WRT+ C + C + Y C C C ++ + C +GC C +
Sbjct: 399 AQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPN 458
Query: 236 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280
G ++ CV +C C +G Y P +V+ ++C CTC +GK
Sbjct: 459 GLIFEDGGCVAPAECPCEFHGTLY-PPGSVVKEDC-NTCTCTSGK 501
Score = 67.0 bits (162), Expect = 5e-11
Identities = 87/344 (25%), Positives = 123/344 (35%), Gaps = 72/344 (20%)
Query: 53 GLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDCIPS 109
GLCG +GD +D +GS G A + F +SW+ VP S L D +
Sbjct: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDSCAT 2301
Query: 110 HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSN 169
C P L ++S+ T S+CH+ V P+ + I D + C
Sbjct: 2302 TDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQPCVA 2345
Query: 170 IHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--- 226
+ YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2346 LTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDGILG 2397
Query: 227 ---------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLIDNC 270
EGC C G + + C+P +C C + GV E + L C
Sbjct: 2398 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 271 RQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQ 330
+ Q C A +V + C PS SC+ + L T + Q
Sbjct: 2458 QHQ--CQAPDTIVPVDLGC-------PSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2508
Query: 331 PLKVLLPLLSPDPCHGV--TCRPQETCKEQGGQGVCLPNYEATC 372
L C G+ TCRP + C P+Y C
Sbjct: 2509 TL-----------CEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 66.6 bits (161), Expect = 6e-11
Identities = 47/162 (29%), Positives = 70/162 (43%), Gaps = 20/162 (12%)
Query: 39 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 98
V V + Q+ GLCGN++ ++ + P + N EFG+SW V
Sbjct: 1098 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV----------E 1147
Query: 99 CPPGSEDCIPSHKCP-PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL- 156
CP + P C L + + K+E C +L S CH +VD +C+ D
Sbjct: 1148 CP---DTLDPRDMCVLNPLREPFAKKE-CSILLSEV--FEICHPVVDVTWFYSNCLTDTC 1201
Query: 157 -CLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
C GG+ C+++ AY C G V+ WRT CP +C
Sbjct: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLCPYDC 1242
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 424
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW- 543
+++D V + + G GLCGN + +P +D V +G L + + SW
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 544 -RAPGWDP 550
+AP P
Sbjct: 315 EQAPNQPP 322
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 147 bits (371), Expect = 3e-35
Identities = 143/565 (25%), Positives = 215/565 (38%), Gaps = 79/565 (13%)
Query: 23 IETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANE 79
+ T+ G+RV YD L Y++V + + GLCG +NG+ +DDF P G
Sbjct: 546 VRTNVGVRVLYDREGLRLYLQVDQ--RWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 603
Query: 80 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139
FGNSW+ + SP + +P P C L+ + C +L+ + C
Sbjct: 604 FGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM--FAPC 651
Query: 140 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199
+ P + C D C G LC+ + Y C+ G V+ C + C
Sbjct: 652 SAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 709
Query: 200 NSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA--CVPIQ 248
+ Y C C C L++P C +D C EGC C + QA CVP
Sbjct: 710 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 769
Query: 249 QCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEH----SCKPGQVCQPSGGI--- 301
QC C+ GV Y P + + C C G V+ C +C GQV +
Sbjct: 770 QCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCSDLHTD 826
Query: 302 ------LSCVTKVTLRSLAQTGVDVEGAA----ILYNGQPLKVLLPLLSPDPCHG----- 346
+C ++ S++ G + G A +L +G LP P G
Sbjct: 827 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD--ACFLPEECPCTWKGKEYFP 884
Query: 347 --VTCRPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 403
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 885 GDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL----- 939
Query: 404 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 463
V + F+V +N N + + + +++ +G ++ + D+ G P
Sbjct: 940 --VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPSP 988
Query: 464 VSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 520
S D + V + F + + +D V V + G + GLCGN D
Sbjct: 989 ESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLK 1048
Query: 521 PNNDQVFPNGTLAPSIPIWGGSWRA 545
N+ P + +G SW A
Sbjct: 1049 TINEMRTPENLELTNPQEFGSSWAA 1073
Score = 129 bits (323), Expect = 1e-29
Identities = 84/285 (29%), Positives = 128/285 (44%), Gaps = 20/285 (7%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
++LP V+ G R Q V++ +A+D V + + GLCGN N
Sbjct: 160 VQLPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNA 217
Query: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT---PCPPGSEDCIPSHKCPPELE 117
DPKDD +G + EF +SW+E P+ P P T P PP C+ + P ++
Sbjct: 218 DPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPP----CLQQN--PGTMQ 271
Query: 118 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 177
Y++ C L P P +CH V P C DLC G+++ C + Y AC
Sbjct: 272 GVYEQ---CEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARAC 326
Query: 178 QAAGGHVEPWRTE-TFCPMECPPNSH-YELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 235
AG ++ WRT+ C + C + Y C C C ++ + C +GC C +
Sbjct: 327 AQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPN 386
Query: 236 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280
G ++ CV +C C +G Y P +V+ ++C CTC +GK
Sbjct: 387 GLIFEDGGCVAPAECPCEFHGTLY-PPGSVVKEDC-NTCTCTSGK 429
Score = 67.0 bits (162), Expect = 5e-11
Identities = 87/344 (25%), Positives = 123/344 (35%), Gaps = 72/344 (20%)
Query: 53 GLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDCIPS 109
GLCG +GD +D +GS G A + F +SW+ VP S L D +
Sbjct: 2174 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDSCAT 2229
Query: 110 HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSN 169
C P L ++S+ T S+CH+ V P+ + I D + C
Sbjct: 2230 TDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQPCVA 2273
Query: 170 IHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--- 226
+ YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2274 LTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDGILG 2325
Query: 227 ---------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLIDNC 270
EGC C G + + C+P +C C + GV E + L C
Sbjct: 2326 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 271 RQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQ 330
+ Q C A +V + C PS SC+ + L T + Q
Sbjct: 2386 QHQ--CQAPDTIVPVDLGC-------PSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2436
Query: 331 PLKVLLPLLSPDPCHGV--TCRPQETCKEQGGQGVCLPNYEATC 372
L C G+ TCRP + C P+Y C
Sbjct: 2437 TL-----------CEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 66.6 bits (161), Expect = 6e-11
Identities = 47/162 (29%), Positives = 70/162 (43%), Gaps = 20/162 (12%)
Query: 39 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 98
V V + Q+ GLCGN++ ++ + P + N EFG+SW V
Sbjct: 1026 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV----------E 1075
Query: 99 CPPGSEDCIPSHKCP-PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL- 156
CP + P C L + + K+E C +L S CH +VD +C+ D
Sbjct: 1076 CP---DTLDPRDMCVLNPLREPFAKKE-CSILLSEV--FEICHPVVDVTWFYSNCLTDTC 1129
Query: 157 -CLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
C GG+ C+++ AY C G V+ WRT CP +C
Sbjct: 1130 GCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLCPYDC 1170
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 424
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW- 543
+++D V + + G GLCGN + +P +D V +G L + + SW
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 544 -RAPGWDP 550
+AP P
Sbjct: 243 EQAPNQPP 250
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 147 bits (371), Expect = 3e-35
Identities = 143/565 (25%), Positives = 215/565 (38%), Gaps = 79/565 (13%)
Query: 23 IETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANE 79
+ T+ G+RV YD L Y++V + + GLCG +NG+ +DDF P G
Sbjct: 618 VRTNVGVRVLYDREGLRLYLQVDQ--RWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQL 675
Query: 80 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139
FGNSW+ + SP + +P P C L+ + C +L+ + C
Sbjct: 676 FGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM--FAPC 723
Query: 140 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199
+ P + C D C G LC+ + Y C+ G V+ C + C
Sbjct: 724 SAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEA 781
Query: 200 NSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA--CVPIQ 248
+ Y C C C L++P C +D C EGC C + QA CVP
Sbjct: 782 SKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRN 841
Query: 249 QCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEH----SCKPGQVCQPSGGI--- 301
QC C+ GV Y P + + C C G V+ C +C GQV +
Sbjct: 842 QCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCSDLHTD 898
Query: 302 ------LSCVTKVTLRSLAQTGVDVEGAA----ILYNGQPLKVLLPLLSPDPCHG----- 346
+C ++ S++ G + G A +L +G LP P G
Sbjct: 899 LELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGD--ACFLPEECPCTWKGKEYFP 956
Query: 347 --VTCRPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 403
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 957 GDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL----- 1011
Query: 404 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 463
V + F+V +N N + + + +++ +G ++ + D+ G P
Sbjct: 1012 --VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------NPSP 1060
Query: 464 VSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRN 520
S D + V + F + + +D V V + G + GLCGN D
Sbjct: 1061 ESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLK 1120
Query: 521 PNNDQVFPNGTLAPSIPIWGGSWRA 545
N+ P + +G SW A
Sbjct: 1121 TINEMRTPENLELTNPQEFGSSWAA 1145
Score = 129 bits (323), Expect = 1e-29
Identities = 84/285 (29%), Positives = 128/285 (44%), Gaps = 20/285 (7%)
Query: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
++LP V+ G R Q V++ +A+D V + + GLCGN N
Sbjct: 232 VQLPHVM--GSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNA 289
Query: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT---PCPPGSEDCIPSHKCPPELE 117
DPKDD +G + EF +SW+E P+ P P T P PP C+ + P ++
Sbjct: 290 DPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPP----CLQQN--PGTMQ 343
Query: 118 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 177
Y++ C L P P +CH V P C DLC G+++ C + Y AC
Sbjct: 344 GVYEQ---CEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARAC 398
Query: 178 QAAGGHVEPWRTE-TFCPMECPPNSH-YELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 235
AG ++ WRT+ C + C + Y C C C ++ + C +GC C +
Sbjct: 399 AQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPN 458
Query: 236 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 280
G ++ CV +C C +G Y P +V+ ++C CTC +GK
Sbjct: 459 GLIFEDGGCVAPAECPCEFHGTLY-PPGSVVKEDC-NTCTCTSGK 501
Score = 67.0 bits (162), Expect = 5e-11
Identities = 87/344 (25%), Positives = 123/344 (35%), Gaps = 72/344 (20%)
Query: 53 GLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDCIPS 109
GLCG +GD +D +GS G A + F +SW+ VP S L D +
Sbjct: 2246 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDSCAT 2301
Query: 110 HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSN 169
C P L ++S+ T S+CH+ V P+ + I D + C
Sbjct: 2302 TDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQPCVA 2345
Query: 170 IHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--- 226
+ YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2346 LTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDGILG 2397
Query: 227 ---------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLIDNC 270
EGC C G + + C+P +C C + GV E + L C
Sbjct: 2398 PLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 271 RQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQ 330
+ Q C A +V + C PS SC+ + L T + Q
Sbjct: 2458 QHQ--CQAPDTIVPVDLGC-------PSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQ 2508
Query: 331 PLKVLLPLLSPDPCHGV--TCRPQETCKEQGGQGVCLPNYEATC 372
L C G+ TCRP + C P+Y C
Sbjct: 2509 TL-----------CEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 66.6 bits (161), Expect = 6e-11
Identities = 47/162 (29%), Positives = 70/162 (43%), Gaps = 20/162 (12%)
Query: 39 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 98
V V + Q+ GLCGN++ ++ + P + N EFG+SW V
Sbjct: 1098 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAV----------E 1147
Query: 99 CPPGSEDCIPSHKCP-PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL- 156
CP + P C L + + K+E C +L S CH +VD +C+ D
Sbjct: 1148 CP---DTLDPRDMCVLNPLREPFAKKE-CSILLSEV--FEICHPVVDVTWFYSNCLTDTC 1201
Query: 157 -CLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
C GG+ C+++ AY C G V+ WRT CP +C
Sbjct: 1202 GCSQGGDCECFCASVSAYAHQCCQHGVAVD-WRTPRLCPYDC 1242
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 366 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 424
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW- 543
+++D V + + G GLCGN + +P +D V +G L + + SW
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 544 -RAPGWDP 550
+AP P
Sbjct: 315 EQAPNQPP 322
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 142 bits (359), Expect = 7e-34
Identities = 127/533 (23%), Positives = 215/533 (40%), Gaps = 54/533 (10%)
Query: 21 VVIETDFGLRVAYDLV---YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNA 77
++++T FGL++ + + Y+++T + ++ GLCG +NG+ +DDF P+G G
Sbjct: 524 ILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTP 581
Query: 78 NEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLS 137
N+W S C P P I ++ C ++ +
Sbjct: 582 QLHANAWRV---SSTCFAPVHVPVVDPCNIN--------QQNIGYAAHCDVIHQEL--FA 628
Query: 138 SCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTE-TFCPME 196
CH + P + C D C G S LC+ + Y C G ++ +RT+ +FC +
Sbjct: 629 PCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPID-FRTQISFCAVV 685
Query: 197 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG--QACVPIQQCGCYH 254
C Y C+ C C +LS+P QC D CAEGC C G Y CVPI C C++
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 255 NGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLA 314
G Y+P + LI C C G V + + +C C + L
Sbjct: 746 RGSVYQPGE--LIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDC--RFPDPELP 801
Query: 315 QTGVDVEGAAILYNGQPLKVLLPLLSPDPC-HGVTCRPQETCKEQGGQGVCLPNYEATCW 373
GV+ E L + PC G C P C+ +G A C
Sbjct: 802 AGGVNCETTC-----ANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNCTYYPCPAVCT 854
Query: 374 LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRV 433
++GD HY+SFDG ++D+ C L + + + +V +N+ + + +
Sbjct: 855 IYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKCFDNDIVCSKS 907
Query: 434 VTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF---GLQV 490
V ++ T I ++ D K + +G + + + + +V F + +
Sbjct: 908 VLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIVVYFPEKDITI 959
Query: 491 SYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 543
+D + + + + + GLCGN D+ +ND N + ++G SW
Sbjct: 960 LWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW 1012
Score = 107 bits (267), Expect = 3e-23
Identities = 76/287 (26%), Positives = 116/287 (40%), Gaps = 26/287 (9%)
Query: 10 GQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKP 69
GQI + ++++T FG +A+D + + + + ++ + CGLCGNYN DDF
Sbjct: 153 GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIIL 212
Query: 70 NGSQAGNANEFGNSWEEVVPD------SPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKE 123
+ F NSW PD +P P PC G P E + K
Sbjct: 213 QEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGM----------PAFEAIFFK- 261
Query: 124 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGH 183
C +L P SCH+ +DP + C+ DLC + C Y AC AG
Sbjct: 262 --CQILLQ--FPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYP 316
Query: 184 VEPWRTE-TFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQ 242
++ WR + C +C + + C C C+ C +GC C G + +
Sbjct: 317 IQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNG 376
Query: 243 ACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSC 289
C+ ++ C C +G+ Y I+ +C C G V C E C
Sbjct: 377 TCISLENCPCGFHGLAYSVGSK--IEQECTECVC-VGGVWNCTEQDC 420
Score = 67.8 bits (164), Expect = 3e-11
Identities = 50/179 (27%), Positives = 79/179 (44%), Gaps = 18/179 (10%)
Query: 21 VVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 80
VV + + + +D + + V + ++ GLCGN++ +D N + NA F
Sbjct: 949 VVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVF 1008
Query: 81 GNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCH 140
G+SW +SP PC +K P Y K+E C +L S +SC
Sbjct: 1009 GDSWALGQCESPDETIKPCE------AHQNKFP------YAKKE-CSILYSDI--FASCR 1053
Query: 141 KLVDPQGPLKDCIFDLCLG--GGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
++D K+C D C GG+ LC++I AY C G + WR+ T C ++C
Sbjct: 1054 NVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 66.2 bits (160), Expect = 8e-11
Identities = 54/210 (25%), Positives = 90/210 (42%), Gaps = 21/210 (10%)
Query: 345 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 395
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 396 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 453
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 454 RVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 513
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 514 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 543
CGN + ++D + I ++ SW
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSW 227
Score = 55.5 bits (132), Expect = 1e-07
Identities = 62/271 (22%), Positives = 101/271 (37%), Gaps = 53/271 (19%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAY-------DLVYYVRVTVPGNYYQQMCGLC 55
+P+ ++ ++ GS VI T GL + + D+ + R + +Y + +CG+C
Sbjct: 1525 VPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL-SSYTEGLCGIC 1583
Query: 56 GNYNGDPKDDFQKPNGSQAGNANEFG---NSWE-----EVVPDSPCLPPTPCPPGSEDCI 107
N DP DD + NG+ N + G SWE EV P T DC
Sbjct: 1584 ---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCT-----EHDC- 1634
Query: 108 PSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILC 167
+C L ++ CH V P+ + + + C
Sbjct: 1635 --SQCIDLLNRRI---------------FIPCHDKVSPEDFCEKMWINYTYFW---NYEC 1674
Query: 168 SNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGC 227
+ AYV+ C ++ WRT +C + CP Y+ C C + L+ C
Sbjct: 1675 DALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCE-ARTCLNQWFYGHTSC 1732
Query: 228 ---AEGCQCDSGFLY---NGQACVPIQQCGC 252
E C C G + + C+P ++C C
Sbjct: 1733 LNLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763
Score = 53.5 bits (127), Expect = 5e-07
Identities = 44/180 (24%), Positives = 80/180 (44%), Gaps = 21/180 (11%)
Query: 372 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTK----NQNRGNPA 427
C + GD H+ +FDGR + F G C Y+L V G FT+T + QN G
Sbjct: 424 CSVVGDSHFTTFDGRHYSFIGMCQYIL-------VKGTGKDKFTITLQKAPCEQNLGLVC 476
Query: 428 VSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSV-ADGRISV-TQGASKALLVAD 485
+ + ++ +++ R +LT+ +G + + T + LL
Sbjct: 477 LQSITLILEDDFNKQVTLG-------RGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTT 529
Query: 486 FGLQVSYDWNW-RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
FGL++ + + R+ + L S++ GLCG + N +D + P+G + + + +WR
Sbjct: 530 FGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWR 589
Score = 32.0 bits (71), Expect = 1.6
Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 33/191 (17%)
Query: 358 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 415
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 416 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 470
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 471 ISVTQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 521
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 522 NNDQVFPNGTL 532
++D NGT+
Sbjct: 1588 DDDLRMQNGTI 1598
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 142 bits (359), Expect = 7e-34
Identities = 127/533 (23%), Positives = 215/533 (40%), Gaps = 54/533 (10%)
Query: 21 VVIETDFGLRVAYDLV---YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNA 77
++++T FGL++ + + Y+++T + ++ GLCG +NG+ +DDF P+G G
Sbjct: 524 ILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTP 581
Query: 78 NEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLS 137
N+W S C P P I ++ C ++ +
Sbjct: 582 QLHANAWRV---SSTCFAPVHVPVVDPCNIN--------QQNIGYAAHCDVIHQEL--FA 628
Query: 138 SCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTE-TFCPME 196
CH + P + C D C G S LC+ + Y C G ++ +RT+ +FC +
Sbjct: 629 PCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPID-FRTQISFCAVV 685
Query: 197 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG--QACVPIQQCGCYH 254
C Y C+ C C +LS+P QC D CAEGC C G Y CVPI C C++
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 255 NGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLA 314
G Y+P + LI C C G V + + +C C + L
Sbjct: 746 RGSVYQPGE--LIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDC--RFPDPELP 801
Query: 315 QTGVDVEGAAILYNGQPLKVLLPLLSPDPC-HGVTCRPQETCKEQGGQGVCLPNYEATCW 373
GV+ E L + PC G C P C+ +G A C
Sbjct: 802 AGGVNCETTC-----ANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNCTYYPCPAVCT 854
Query: 374 LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRV 433
++GD HY+SFDG ++D+ C L + + + +V +N+ + + +
Sbjct: 855 IYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKCFDNDIVCSKS 907
Query: 434 VTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF---GLQV 490
V ++ T I ++ D K + +G + + + + +V F + +
Sbjct: 908 VLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIVVYFPEKDITI 959
Query: 491 SYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 543
+D + + + + + GLCGN D+ +ND N + ++G SW
Sbjct: 960 LWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW 1012
Score = 107 bits (267), Expect = 3e-23
Identities = 76/287 (26%), Positives = 116/287 (40%), Gaps = 26/287 (9%)
Query: 10 GQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKP 69
GQI + ++++T FG +A+D + + + + ++ + CGLCGNYN DDF
Sbjct: 153 GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIIL 212
Query: 70 NGSQAGNANEFGNSWEEVVPD------SPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKE 123
+ F NSW PD +P P PC G P E + K
Sbjct: 213 QEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGM----------PAFEAIFFK- 261
Query: 124 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGH 183
C +L P SCH+ +DP + C+ DLC + C Y AC AG
Sbjct: 262 --CQILLQ--FPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYP 316
Query: 184 VEPWRTE-TFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQ 242
++ WR + C +C + + C C C+ C +GC C G + +
Sbjct: 317 IQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNG 376
Query: 243 ACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSC 289
C+ ++ C C +G+ Y I+ +C C G V C E C
Sbjct: 377 TCISLENCPCGFHGLAYSVGSK--IEQECTECVC-VGGVWNCTEQDC 420
Score = 67.8 bits (164), Expect = 3e-11
Identities = 50/179 (27%), Positives = 79/179 (44%), Gaps = 18/179 (10%)
Query: 21 VVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 80
VV + + + +D + + V + ++ GLCGN++ +D N + NA F
Sbjct: 949 VVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVF 1008
Query: 81 GNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCH 140
G+SW +SP PC +K P Y K+E C +L S +SC
Sbjct: 1009 GDSWALGQCESPDETIKPCE------AHQNKFP------YAKKE-CSILYSDI--FASCR 1053
Query: 141 KLVDPQGPLKDCIFDLCLG--GGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
++D K+C D C GG+ LC++I AY C G + WR+ T C ++C
Sbjct: 1054 NVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 66.2 bits (160), Expect = 8e-11
Identities = 54/210 (25%), Positives = 90/210 (42%), Gaps = 21/210 (10%)
Query: 345 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 395
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 396 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 453
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 454 RVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 513
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 514 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 543
CGN + ++D + I ++ SW
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSW 227
Score = 55.8 bits (133), Expect = 1e-07
Identities = 62/271 (22%), Positives = 101/271 (37%), Gaps = 53/271 (19%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAY-------DLVYYVRVTVPGNYYQQMCGLC 55
+P+ ++ ++ GS VI T GL + + D+ + R + +Y + +CG+C
Sbjct: 1525 VPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL-SSYTEGLCGIC 1583
Query: 56 GNYNGDPKDDFQKPNGSQAGNANEFG---NSWE-----EVVPDSPCLPPTPCPPGSEDCI 107
N DP DD + NG+ N + G SWE EV P T DC
Sbjct: 1584 ---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCT-----EHDC- 1634
Query: 108 PSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILC 167
+C L ++ CH V P+ + + + C
Sbjct: 1635 --SQCIDLLNRRI---------------FIPCHDKVSPEDFCEKMWINYTYFW---NYEC 1674
Query: 168 SNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGC 227
+ AYV+ C ++ WRT +C + CP Y+ C C + L+ C
Sbjct: 1675 DALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCE-ARTCLNQWFYGHTSC 1732
Query: 228 ---AEGCQCDSGFLY---NGQACVPIQQCGC 252
E C C G + + C+P ++C C
Sbjct: 1733 LNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 53.5 bits (127), Expect = 5e-07
Identities = 44/180 (24%), Positives = 80/180 (44%), Gaps = 21/180 (11%)
Query: 372 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTK----NQNRGNPA 427
C + GD H+ +FDGR + F G C Y+L V G FT+T + QN G
Sbjct: 424 CSVVGDSHFTTFDGRHYSFIGMCQYIL-------VKGTGKDKFTITLQKAPCEQNLGLVC 476
Query: 428 VSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSV-ADGRISV-TQGASKALLVAD 485
+ + ++ +++ R +LT+ +G + + T + LL
Sbjct: 477 LQSITLILEDDFNKQVTLG-------RGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTT 529
Query: 486 FGLQVSYDWNW-RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
FGL++ + + R+ + L S++ GLCG + N +D + P+G + + + +WR
Sbjct: 530 FGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWR 589
Score = 32.0 bits (71), Expect = 1.6
Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 33/191 (17%)
Query: 358 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 415
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 416 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 470
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 471 ISVTQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 521
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 522 NNDQVFPNGTL 532
++D NGT+
Sbjct: 1588 DDDLRMQNGTI 1598
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
Length = 2250
Score = 142 bits (359), Expect = 7e-34
Identities = 127/533 (23%), Positives = 215/533 (40%), Gaps = 54/533 (10%)
Query: 21 VVIETDFGLRVAYDLV---YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNA 77
++++T FGL++ + + Y+++T + ++ GLCG +NG+ +DDF P+G G
Sbjct: 524 ILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTP 581
Query: 78 NEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLS 137
N+W S C P P I ++ C ++ +
Sbjct: 582 QLHANAWRV---SSTCFAPVHVPVVDPCNIN--------QQNIGYAAHCDVIHQEL--FA 628
Query: 138 SCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTE-TFCPME 196
CH + P + C D C G S LC+ + Y C G ++ +RT+ +FC +
Sbjct: 629 PCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPID-FRTQISFCAVV 685
Query: 197 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG--QACVPIQQCGCYH 254
C Y C+ C C +LS+P QC D CAEGC C G Y CVPI C C++
Sbjct: 686 CQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 255 NGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLA 314
G Y+P + LI C C G V + + +C C + L
Sbjct: 746 RGSVYQPGE--LIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDC--RFPDPELP 801
Query: 315 QTGVDVEGAAILYNGQPLKVLLPLLSPDPC-HGVTCRPQETCKEQGGQGVCLPNYEATCW 373
GV+ E L + PC G C P C+ +G A C
Sbjct: 802 AGGVNCETTC-----ANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNCTYYPCPAVCT 854
Query: 374 LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRV 433
++GD HY+SFDG ++D+ C L + + + +V +N+ + + +
Sbjct: 855 IYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKCFDNDIVCSKS 907
Query: 434 VTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF---GLQV 490
V ++ T I ++ D K + +G + + + + +V F + +
Sbjct: 908 VLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIVVYFPEKDITI 959
Query: 491 SYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 543
+D + + + + + GLCGN D+ +ND N + ++G SW
Sbjct: 960 LWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW 1012
Score = 107 bits (267), Expect = 3e-23
Identities = 76/287 (26%), Positives = 116/287 (40%), Gaps = 26/287 (9%)
Query: 10 GQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKP 69
GQI + ++++T FG +A+D + + + + ++ + CGLCGNYN DDF
Sbjct: 153 GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIIL 212
Query: 70 NGSQAGNANEFGNSWEEVVPD------SPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKE 123
+ F NSW PD +P P PC G P E + K
Sbjct: 213 QEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGM----------PAFEAIFFK- 261
Query: 124 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGH 183
C +L P SCH+ +DP + C+ DLC + C Y AC AG
Sbjct: 262 --CQILLQ--FPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHAGYP 316
Query: 184 VEPWRTE-TFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQ 242
++ WR + C +C + + C C C+ C +GC C G + +
Sbjct: 317 IQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNG 376
Query: 243 ACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSC 289
C+ ++ C C +G+ Y I+ +C C G V C E C
Sbjct: 377 TCISLENCPCGFHGLAYSVGSK--IEQECTECVC-VGGVWNCTEQDC 420
Score = 67.8 bits (164), Expect = 3e-11
Identities = 50/179 (27%), Positives = 79/179 (44%), Gaps = 18/179 (10%)
Query: 21 VVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 80
VV + + + +D + + V + ++ GLCGN++ +D N + NA F
Sbjct: 949 VVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVF 1008
Query: 81 GNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCH 140
G+SW +SP PC +K P Y K+E C +L S +SC
Sbjct: 1009 GDSWALGQCESPDETIKPCE------AHQNKFP------YAKKE-CSILYSDI--FASCR 1053
Query: 141 KLVDPQGPLKDCIFDLCLG--GGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC 197
++D K+C D C GG+ LC++I AY C G + WR+ T C ++C
Sbjct: 1054 NVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 66.2 bits (160), Expect = 8e-11
Identities = 54/210 (25%), Positives = 90/210 (42%), Gaps = 21/210 (10%)
Query: 345 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 395
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 396 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 453
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 454 RVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 513
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 514 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 543
CGN + ++D + I ++ SW
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSW 227
Score = 55.8 bits (133), Expect = 1e-07
Identities = 62/271 (22%), Positives = 101/271 (37%), Gaps = 53/271 (19%)
Query: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAY-------DLVYYVRVTVPGNYYQQMCGLC 55
+P+ ++ ++ GS VI T GL + + D+ + R + +Y + +CG+C
Sbjct: 1525 VPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL-SSYTEGLCGIC 1583
Query: 56 GNYNGDPKDDFQKPNGSQAGNANEFG---NSWE-----EVVPDSPCLPPTPCPPGSEDCI 107
N DP DD + NG+ N + G SWE EV P T DC
Sbjct: 1584 ---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCT-----EHDC- 1634
Query: 108 PSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILC 167
+C L ++ CH V P+ + + + C
Sbjct: 1635 --SQCIDLLNRRI---------------FIPCHDKVSPEDFCEKMWINYTYFW---NYEC 1674
Query: 168 SNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGC 227
+ AYV+ C ++ WRT +C + CP Y+ C C + L+ C
Sbjct: 1675 DALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCE-ARTCLNQWFYGHTSC 1732
Query: 228 ---AEGCQCDSGFLY---NGQACVPIQQCGC 252
E C C G + + C+P ++C C
Sbjct: 1733 LNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 53.5 bits (127), Expect = 5e-07
Identities = 44/180 (24%), Positives = 80/180 (44%), Gaps = 21/180 (11%)
Query: 372 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTK----NQNRGNPA 427
C + GD H+ +FDGR + F G C Y+L V G FT+T + QN G
Sbjct: 424 CSVVGDSHFTTFDGRHYSFIGMCQYIL-------VKGTGKDKFTITLQKAPCEQNLGLVC 476
Query: 428 VSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSV-ADGRISV-TQGASKALLVAD 485
+ + ++ +++ R +LT+ +G + + T + LL
Sbjct: 477 LQSITLILEDDFNKQVTLG-------RGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTT 529
Query: 486 FGLQVSYDWNW-RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
FGL++ + + R+ + L S++ GLCG + N +D + P+G + + + +WR
Sbjct: 530 FGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWR 589
Score = 32.0 bits (71), Expect = 1.6
Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 33/191 (17%)
Query: 358 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 415
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 416 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 470
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 471 ISVTQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 521
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 522 NNDQVFPNGTL 532
++D NGT+
Sbjct: 1588 DDDLRMQNGTI 1598
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 127 bits (319), Expect = 3e-29
Identities = 82/244 (33%), Positives = 110/244 (45%), Gaps = 21/244 (8%)
Query: 18 GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNA 77
G V++ GL+V +D V V+VPG+Y + CGLCGN+NG +DD Q P G +
Sbjct: 1245 GHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSE 1304
Query: 78 NEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLS 137
FGNSW+ P PC G E P ++ CG+L S P S
Sbjct: 1305 AAFGNSWQ---VSEGLWPGRPCSAGRE-VDPCRAAGYRARREANAR--CGVLKS--SPFS 1356
Query: 138 SCHKLVDPQGPLKDCIFDLCLGGGNLS---ILCSNIHAYVSACQAAGGHVEP-WRTETFC 193
CH +V P+ C++DLC G S LC + AY S C+ AG V P WR T C
Sbjct: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAG--VTPTWRGPTLC 1414
Query: 194 PMECPPNSH--YELCADTCSLGCSALSAP-----PQCQDGCAEGCQCDSGFLYNGQACVP 246
+ CP ++ C C C P C C GCQC +G + + C+P
Sbjct: 1415 VVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIP 1474
Query: 247 IQQC 250
+ C
Sbjct: 1475 PEAC 1478
Score = 119 bits (298), Expect = 8e-27
Identities = 117/385 (30%), Positives = 151/385 (39%), Gaps = 101/385 (26%)
Query: 193 CP--MECPPNSHY----ELCADTCSLGCSALS--------APP------QCQD------- 225
CP + CPP+ + C TC+ S S APP QCQD
Sbjct: 996 CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIH 1055
Query: 226 -GCAE-GCQCDSGFLYNGQAC----VPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAG 279
C E C G C P Q C H G + +D C C+C AG
Sbjct: 1056 QACPELSCPLSERHTPPGSCCPVCRAPTQSC--VHQGREVASGERWTVDTCTS-CSCMAG 1112
Query: 280 KVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLL 339
V CQ C P LSC G D P L
Sbjct: 1113 -TVRCQSQRCSP----------LSC------------GPDKA---------------PAL 1134
Query: 340 SPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLA 399
SP C C CLP A+C +GDPHY +FDGR FQG+C+YVLA
Sbjct: 1135 SPGSC----------CPR------CLPR-PASCMAFGDPHYRTFDGRLLHFQGSCSYVLA 1177
Query: 400 TTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVL 459
G F+V N +RG V++ + V V + + +D G V V+G
Sbjct: 1178 KDCHSG-------DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQD--GAVTVDGHP 1228
Query: 460 TALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDR 519
ALP + + + V +L A GLQV +D +V+V++P SY G CGLCGN +
Sbjct: 1229 VALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNG 1287
Query: 520 NPNNDQVFPNGTLAPSIPIWGGSWR 544
+D P G L PS +G SW+
Sbjct: 1288 FAQDDLQGPEGLLLPSEAAFGNSWQ 1312
Score = 33.5 bits (75), Expect = 0.57
Identities = 65/292 (22%), Positives = 87/292 (29%), Gaps = 39/292 (13%)
Query: 92 PCLPPTPCP-PGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLK 150
PC PP PC PG IP CP +YQ ++ S T L
Sbjct: 287 PC-PPVPCRHPGK---IPGQCCPVCDGCEYQGHQY---QSQETFRLQERGL--------- 330
Query: 151 DCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPM------ECPPNSHYE 204
C+ C G + C V+ C P CP E +E
Sbjct: 331 -CVRCSCQAG---EVSCEEQECPVTPCAL------PASGRQLCPACELDGEEFAEGVQWE 380
Query: 205 LCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQT 264
C+ C P+C C G C C YH+ VY +
Sbjct: 381 PDGRPCT-ACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDSC-TYHSQVYANGQNF 438
Query: 265 VLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAA 324
D+ C C G V C C P +P G C + + + V V+G +
Sbjct: 439 TDADSPCHACHCQDG-TVTCSLVDCPPTTCARPQSGPGQCCPRCP-DCILEEEVFVDGES 496
Query: 325 ILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWG 376
+ P + C C P+ C G C PN + C G
Sbjct: 497 FSHPRDPCQECRCQEGHAHCQPRPC-PRAPCAHP-LPGTCCPNDCSGCAFGG 546
Score = 32.0 bits (71), Expect = 1.6
Identities = 76/321 (23%), Positives = 104/321 (32%), Gaps = 78/321 (24%)
Query: 84 WEEVVPDSP-CLPPTPCP-PGSEDCIPSHKCPPELEKKY-QKEEF------CGLLSSPTG 134
WE V P P CP P DC P L + Y +EF C L + G
Sbjct: 688 WEGSVSCEPKACAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNLCTCLGG 747
Query: 135 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 194
++ + +P G C L + G+ C + A G P + C
Sbjct: 748 FVTCGRRPCEPPG----CSHPL-IPSGHCCPTCQGCRYH--GVTTASGETLPDPLDPTCS 800
Query: 195 M-------------ECPPN--SHYELCADTCSLGCSALSAPPQCQDG--------CAEGC 231
+ CPP H C + S LS + QDG E C
Sbjct: 801 LCTCQEGSMRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWC 860
Query: 232 QCDSGFLYNGQACVPIQ------------------QC-GCYHNGVYY-EPEQTVLIDNCR 271
+C +G + +CV +Q +C GC +G + E + V D+
Sbjct: 861 RCQAGQV----SCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSAC 916
Query: 272 QQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQP 331
C CH G VV C C QP G C + + D E Y +P
Sbjct: 917 SSCVCHEG-VVTCARIQC-ISSCAQPRQGPHDCCPQCS---------DCEHEGRKY--EP 963
Query: 332 LKVLLPLLSPDPCHGVTCRPQ 352
+ P DPC C PQ
Sbjct: 964 GESFQP--GADPCEVCICEPQ 982
>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
Length = 1950
Score = 121 bits (303), Expect = 2e-27
Identities = 77/270 (28%), Positives = 123/270 (45%), Gaps = 28/270 (10%)
Query: 23 IETDFGLRVAYDLVYYVR--VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 80
+ET F +++ +V ++ V++P N + GLCG+YN +DDF + F
Sbjct: 937 VETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAF 996
Query: 81 GNSWEEVVPDSPCLPPTPCPPGS-EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 139
NSWE + CP G+ CI +EK+ E CG+L +GPL+SC
Sbjct: 997 ANSWEMM----------SCPKGNPSSCI-------SIEKEKFAERHCGILLDSSGPLASC 1039
Query: 140 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 199
H +V+P+ ++C C + LC+ + YV AC ++ WRT C CP
Sbjct: 1040 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPS 1098
Query: 200 NSHYELCADTCSLGCSALSAPPQ---CQDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHN 255
++ C+ C +LS + +D +GC C N + CV QC CY N
Sbjct: 1099 GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIN 1158
Query: 256 GVYYEPEQTVLIDNCRQQCTCHAGKVVVCQ 285
+P + + D+ +C C G +++CQ
Sbjct: 1159 DEVMQPGKLIHTDD--NKCVCRDG-ILLCQ 1185
Score = 102 bits (253), Expect = 1e-21
Identities = 79/246 (32%), Positives = 103/246 (41%), Gaps = 32/246 (13%)
Query: 50 QMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT-PCPPGSEDCIP 108
++CGLCGN NGD KDDF S A A EFGNSW+ S + T PC D P
Sbjct: 1263 KVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPC-----DSNP 1317
Query: 109 SHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSIL 166
C +K C +L T CH VDP CI + C G
Sbjct: 1318 --YCKAWAVRK------CEILRDST--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1367
Query: 167 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNS-------HYELCADTCSLGCSALSA 219
C+ + Y AC A G V WR CP+ C + HYE C + C
Sbjct: 1368 CTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLV 1426
Query: 220 PPQCQ---DGCAEGCQCDSGFL-YNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCT 275
+ +GC C + +L N CV + +C C++N V P V+ DNC + C
Sbjct: 1427 GQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVI--PAGGVIEDNCGRTCY 1484
Query: 276 CHAGKV 281
C AG++
Sbjct: 1485 CIAGQL 1490
Score = 57.8 bits (138), Expect = 3e-08
Identities = 55/200 (27%), Positives = 79/200 (39%), Gaps = 23/200 (11%)
Query: 112 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 171
CP + K Y+ E LS+ +K++ CI + C S C
Sbjct: 660 CPNAVGKSYEVCEDGIQKCGKVAALSNDYKMI--------CIDEYCQTRDKTST-CDTYS 710
Query: 172 AYVSACQAAG-GHVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALSAPPQCQDGC 227
C + G G E WR+++ E CP Y+ C + CS ++ P C
Sbjct: 711 ELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVA--PFQDSEC 768
Query: 228 AEGCQCDSGFLYNG----QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVV 283
GC C G+L + CV +C C +G Y+P + V C QCTC K
Sbjct: 769 VSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAK-WS 826
Query: 284 CQEHSCKPGQVCQPSGGILS 303
C E C PG+ C+ G L+
Sbjct: 827 CTEALC-PGR-CKVEGSSLT 844
Score = 30.8 bits (68), Expect = 3.7
Identities = 13/40 (32%), Positives = 22/40 (55%)
Query: 505 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
++ G VCGLCGN + + +D ++A +G SW+
Sbjct: 1259 AFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK 1298
>gi|37693519 BMP-binding endothelial regulator precursor protein
[Homo sapiens]
Length = 685
Score = 105 bits (261), Expect = 2e-22
Identities = 103/398 (25%), Positives = 153/398 (38%), Gaps = 61/398 (15%)
Query: 193 CPMECP-PNSHYELCADTCSLGCSALSAPPQCQDG---------CAEGCQCDSGFLYNGQ 242
C + C P H +C TC GC + Q Q+G C + C C G +
Sbjct: 145 CVVHCKNPLEHLGMCCPTCP-GC--VFEGVQYQEGEEFQPEGSKCTK-CSCTGGRTQCVR 200
Query: 243 ACVPIQQC----------------------------GCYHNGVYYEPEQTVLIDNCRQQC 274
PI C C Y+ + L DNC C
Sbjct: 201 EVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTA-C 259
Query: 275 TCHAGKVVVCQEHSCKPGQVCQPSGGILS-CVTKVTLRSL--AQTGVDVEGAAILYNGQP 331
TC VVC+ PG Q G C+ +V + + G + +++
Sbjct: 260 TCR-DSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSIN 318
Query: 332 LKVLLPLLSPDPCHGVTCRPQETC---KEQGGQGVC--LPNYEATCWLWGDPHYHSFDGR 386
+ + C C P +C K +G C C ++GDPHY++FDGR
Sbjct: 319 CTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGR 378
Query: 387 KFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIH 446
F+FQGTC YVL T C + +PF V KN R + S+ + V + + +S+
Sbjct: 379 TFNFQGTCQYVL-TKDC----SSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQ 433
Query: 447 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSY 506
+ VR NG ALP I + K A GL++S+D + V+V
Sbjct: 434 QHL--TVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKA--GLEISWDGDSFVEVMAAPHL 489
Query: 507 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
G +CGLCGN + + +D + +G + + SWR
Sbjct: 490 KGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR 527
Score = 90.5 bits (223), Expect = 4e-18
Identities = 60/229 (26%), Positives = 95/229 (41%), Gaps = 12/229 (5%)
Query: 23 IETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGN 82
+ T GL +++D +V V + ++CGLCGNYNG +DD +G+ + ++F
Sbjct: 465 VTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAE 524
Query: 83 SWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKL 142
SW V + C P P +P C ++ K + C L S +CH
Sbjct: 525 SWR-VESNEFCNRPQRKP------VPE-LCQGTVKVKLRAHRECQKLKS--WEFQTCHST 574
Query: 143 VDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPM-ECPPNS 201
VD + C+ D+C + + C + AY ACQ G V W + C +C +
Sbjct: 575 VDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA 633
Query: 202 HYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQC 250
Y+ C C C + C C GC C + + + C+ C
Sbjct: 634 VYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVLHKGRCIKPVLC 682
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.466
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,341,844
Number of Sequences: 37866
Number of extensions: 1651684
Number of successful extensions: 6145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 4754
Number of HSP's gapped (non-prelim): 798
length of query: 593
length of database: 18,247,518
effective HSP length: 108
effective length of query: 485
effective length of database: 14,157,990
effective search space: 6866625150
effective search space used: 6866625150
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.