BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239756319 PREDICTED: hypothetical protein [Homo sapiens] (463 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239756319 PREDICTED: hypothetical protein [Homo sapiens] 949 0.0 gi|239750846 PREDICTED: hypothetical protein [Homo sapiens] 944 0.0 gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo ... 944 0.0 gi|239750574 PREDICTED: hypothetical protein [Homo sapiens] 55 2e-07 gi|169205732 PREDICTED: hypothetical protein [Homo sapiens] 55 2e-07 gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 52 9e-07 gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 52 9e-07 gi|239755920 PREDICTED: hypothetical protein XP_002344746 [Homo ... 50 6e-06 gi|239750438 PREDICTED: hypothetical protein [Homo sapiens] 50 6e-06 gi|239744740 PREDICTED: hypothetical protein XP_002343259 [Homo ... 50 6e-06 gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 44 2e-04 gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo ... 44 2e-04 gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo ... 44 2e-04 gi|109452587 family with sequence similarity 98, member B isofor... 44 2e-04 gi|47132620 keratin 2 [Homo sapiens] 43 5e-04 gi|7710145 methyl-CpG binding domain protein 2 testis-specific i... 42 0.001 gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s... 42 0.001 gi|119395750 keratin 1 [Homo sapiens] 42 0.001 gi|57864582 hornerin [Homo sapiens] 42 0.001 gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 42 0.001 gi|239749709 PREDICTED: hypothetical protein [Homo sapiens] 41 0.003 gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo ... 40 0.003 gi|31542255 hypothetical protein LOC140706 [Homo sapiens] 40 0.003 gi|62122917 filaggrin family member 2 [Homo sapiens] 40 0.004 gi|55956899 keratin 9 [Homo sapiens] 40 0.004 gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo ... 40 0.006 gi|239750393 PREDICTED: hypothetical protein [Homo sapiens] 40 0.006 gi|239744694 PREDICTED: hypothetical protein [Homo sapiens] 40 0.006 gi|9966841 cell death regulator aven [Homo sapiens] 40 0.006 gi|28875797 small protein rich in arginine and glycine [Homo sap... 39 0.008 >gi|239756319 PREDICTED: hypothetical protein [Homo sapiens] Length = 463 Score = 949 bits (2453), Expect = 0.0 Identities = 463/463 (100%), Positives = 463/463 (100%) Query: 1 MGGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 MGGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA Sbjct: 1 MGGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 Query: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV Sbjct: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120 Query: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL Sbjct: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180 Query: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL Sbjct: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240 Query: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ Sbjct: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300 Query: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH Sbjct: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360 Query: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR Sbjct: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420 Query: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC Sbjct: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463 >gi|239750846 PREDICTED: hypothetical protein [Homo sapiens] Length = 463 Score = 944 bits (2440), Expect = 0.0 Identities = 462/463 (99%), Positives = 462/463 (99%) Query: 1 MGGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 MGGGEWG GRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA Sbjct: 1 MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 Query: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV Sbjct: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120 Query: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL Sbjct: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180 Query: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL Sbjct: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240 Query: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ Sbjct: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300 Query: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH Sbjct: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360 Query: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR Sbjct: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420 Query: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC Sbjct: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463 >gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo sapiens] Length = 463 Score = 944 bits (2440), Expect = 0.0 Identities = 462/463 (99%), Positives = 462/463 (99%) Query: 1 MGGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 MGGGEWG GRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA Sbjct: 1 MGGGEWGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 Query: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV Sbjct: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAV 120 Query: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL Sbjct: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHL 180 Query: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL Sbjct: 181 VFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWL 240 Query: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ Sbjct: 241 AGRQVVGLKHLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQ 300 Query: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH Sbjct: 301 TVLPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAAGPRH 360 Query: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR Sbjct: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420 Query: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC Sbjct: 421 REPGLLSSAPQRPVPPGPRRSWSVLRAAELGCGVPARMVAATC 463 >gi|239750574 PREDICTED: hypothetical protein [Homo sapiens] Length = 1297 Score = 54.7 bits (130), Expect = 2e-07 Identities = 128/435 (29%), Positives = 154/435 (35%), Gaps = 104/435 (23%) Query: 18 ASEVVGR-RTRGGVGSCGSVHRHRVQ---------GGGRAGERFAGGGGAALAGGCLRGR 67 A+ V GR R R G+G SV Q G AG GG A AGG L G Sbjct: 783 AAAVSGRGRLRDGLGRVASVAAEGAQVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGA 842 Query: 68 GAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATR 127 +R R+ R + G R R GR+G G G GG+R+ RH Sbjct: 843 VVQRMRQRRVRAGRRRVGARAVAAAGRQGA-GAGGGGRRV---------RHG-------- 884 Query: 128 HGDGGGRVDHA--GGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPP-RHLVFPR 184 HG G + A H+ PA A AA G V G HR G +G P RH Sbjct: 885 HGHGAAVLQRAPCRQQRHLAPAAAAAAAQG---VRAAQGRAHR-PGAQGAPSHRH----- 935 Query: 185 DDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWLAGRQ 244 G R R AA + GG H + A GR+R G Q Sbjct: 936 -----RPGARGRRSRRRAAVALAGGAHPARA-ALGRRR------------------GGGQ 971 Query: 245 VVGLK--HLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQTV 302 VG + H LA Q V + V AA R A R PR L A T Sbjct: 972 AVGARAAHQARLAGGQ---VDQVVVAA---RAGDADGVRGRRPRRL----------ALTA 1015 Query: 303 LPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRL--LVAVRVAAGPRH 360 P L L + D LVD+ R H + R +G D R L AVRVAA Sbjct: 1016 RPELEELLERLHGLQDGLVDVL-RHHRVVRLHPQLAGACDGRAAHLDEEEAVRVAAA--- 1071 Query: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420 AD +L R L V + E ARR + H + A G Sbjct: 1072 --------------ADVHELQRHRRLLAVELHEADGARRQAQTVHPRQVLALAQTLGLQV 1117 Query: 421 REPGLLSSAPQRPVP 435 P L + +R VP Sbjct: 1118 HLPHL--TVGERAVP 1130 Score = 37.0 bits (84), Expect = 0.038 Identities = 77/252 (30%), Positives = 91/252 (36%), Gaps = 37/252 (14%) Query: 43 GGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQG--GDGRWQRRQRGHGGRRGLNGH 100 GGGR AALA R G RV G G+GR GHGG R G Sbjct: 223 GGGRLVAPSRADTHAALAA--FPERDIFHGGRVVALGVVGEGR------GHGGDR--RGG 272 Query: 101 GDGGQRLARRVAQRLQRHAVGAVVATR------HGDGGGRVDHAGGAIHVWPAGAQRAAH 154 G+G +A R+ +GA V R G + H +H +RA H Sbjct: 273 GEGLGTVAAAAPLRVCADDLGAAVGVRGLAGLQEGLDSRHLLHEAQPLH----ARRRAGH 328 Query: 155 GSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQ 214 G RL G G HL ++ G RG Q GG G Q Sbjct: 329 AGSFWLR--GGRDRLRRGGGHTKSHLGVV--TIVPGR-----RGRAAGGQERGGRGRRRQ 379 Query: 215 VRARGRQRAEPQLGLL-LQVLRRVGWLAGRQVVGLKHLEALAAP-QEAAVLEHVPAAWVQ 272 RGR++A P L + + VL G L R L H P Q A H PAA Q Sbjct: 380 QGRRGRRQAGPGLAKVDVDVL--AGALGLRWQWVLVHAGQAGQPLQGQARGPHRPAALAQ 437 Query: 273 RPEAALAWLVRP 284 EA A RP Sbjct: 438 --EALRAAAARP 447 Score = 35.4 bits (80), Expect = 0.11 Identities = 85/305 (27%), Positives = 94/305 (30%), Gaps = 106/305 (34%) Query: 17 KASEVVGRRTRGGVGSC---GSVHRHRVQGGGRA-----------GERFAGGGGAALAGG 62 +A + RR G GS G R R +GGG G R GG G Sbjct: 316 EAQPLHARRRAGHAGSFWLRGGRDRLR-RGGGHTKSHLGVVTIVPGRRGRAAGGQERGG- 373 Query: 63 CLRGRGAERGRRVREQGGDG---------------RWQ---------------------- 85 RGR ++GRR R Q G G RWQ Sbjct: 374 --RGRRRQQGRRGRRQAGPGLAKVDVDVLAGALGLRWQWVLVHAGQAGQPLQGQARGPHR 431 Query: 86 -----------RRQRGHGGR----RGLNGHG-DGGQRLA------RRVAQRLQ------- 116 R HG R RGL G G +G RLA R LQ Sbjct: 432 PAALAQEALRAAAARPHGRRHYRVRGLRGAGPEGAGRLAGPWRGLRLQTLLLQDAPHGGA 491 Query: 117 -RHAVGAVVATRHGD----GGGRVDHAGGAIHVWPAGAQRAAH--GSQLVGERVGSGH-- 167 H + AV AT G G G V AG A PAG Q G G+RV GH Sbjct: 492 HEHVLVAVPATGVGGLVGAGQGAVAAAGNAPERLPAGVQGCGEEVGRGARGDRVAGGHVE 551 Query: 168 -----------RLHGGEGQPPR-HLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQV 215 LHG G P H+ L G L A R GG W Sbjct: 552 VVPVGQQLAICMLHGQLGTAPHAHVPTVLGGALGGRAGLVAAPARRECPARRRGG-CWPR 610 Query: 216 RARGR 220 R R R Sbjct: 611 RPRRR 615 Score = 35.0 bits (79), Expect = 0.14 Identities = 63/198 (31%), Positives = 70/198 (35%), Gaps = 59/198 (29%) Query: 15 PGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAER--- 71 PG+ G + RGG G R R QG R G R AG G A + L G R Sbjct: 359 PGRRGRAAGGQERGGRG------RRRQQG--RRGRRQAGPGLAKVDVDVLAGALGLRWQW 410 Query: 72 -----GRRVREQGGDGRWQRRQ-------------RGHGGR----RGLNGHG-DGGQRLA 108 G+ + G R R R HG R RGL G G +G RLA Sbjct: 411 VLVHAGQAGQPLQGQARGPHRPAALAQEALRAAAARPHGRRHYRVRGLRGAGPEGAGRLA 470 Query: 109 ------RRVAQRLQ--------RHAVGAVVATRHGD----GGGRVDHAGGAIHVWPAGAQ 150 R LQ H + AV AT G G G V AG A PAG Q Sbjct: 471 GPWRGLRLQTLLLQDAPHGGAHEHVLVAVPATGVGGLVGAGQGAVAAAGNAPERLPAGVQ 530 Query: 151 RAAHGSQLVGERVGSGHR 168 GE VG G R Sbjct: 531 GC-------GEEVGRGAR 541 >gi|169205732 PREDICTED: hypothetical protein [Homo sapiens] Length = 1297 Score = 54.7 bits (130), Expect = 2e-07 Identities = 128/435 (29%), Positives = 154/435 (35%), Gaps = 104/435 (23%) Query: 18 ASEVVGR-RTRGGVGSCGSVHRHRVQ---------GGGRAGERFAGGGGAALAGGCLRGR 67 A+ V GR R R G+G SV Q G AG GG A AGG L G Sbjct: 783 AAAVSGRGRLRDGLGRVASVAAEGAQVAWAGAVLVQGHEAGVAGGARGGGAAAGGPLAGA 842 Query: 68 GAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATR 127 +R R+ R + G R R GR+G G G GG+R+ RH Sbjct: 843 VVQRMRQRRVRAGRRRVGARAVAAAGRQGA-GAGGGGRRV---------RHG-------- 884 Query: 128 HGDGGGRVDHA--GGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPP-RHLVFPR 184 HG G + A H+ PA A AA G V G HR G +G P RH Sbjct: 885 HGHGAAVLQRAPCRQQRHLAPAAAAAAAQG---VRAAQGRAHR-PGAQGAPSHRH----- 935 Query: 185 DDVLDGEGVLEARGLRHAAQVVGGGGHLWQVRARGRQRAEPQLGLLLQVLRRVGWLAGRQ 244 G R R AA + GG H + A GR+R G Q Sbjct: 936 -----RPGARGRRSRRRAAVALAGGAHPARA-ALGRRR------------------GGGQ 971 Query: 245 VVGLK--HLEALAAPQEAAVLEHVPAAWVQRPEAALAWLVRPPRDLDEAVVEGEVVAQTV 302 VG + H LA Q V + V AA R A R PR L A T Sbjct: 972 AVGARAAHQARLAGGQ---VDQVVVAA---RAGDADGVRGRRPRRL----------ALTA 1015 Query: 303 LPALRVLPVVGEAVHDELVDLAQRQHLLGRALDGHSGQRDVRVGRL--LVAVRVAAGPRH 360 P L L + D LVD+ R H + R +G D R L AVRVAA Sbjct: 1016 RPELEELLERLHGLQDGLVDVL-RHHRVVRLHPQLAGACDGRAAHLDEEEAVRVAAA--- 1071 Query: 361 LLPRPLLALGPRGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTR 420 AD +L R L V + E ARR + H + A G Sbjct: 1072 --------------ADVHELQRHRRLLAVELHEADGARRQAQTVHPRQVLALAQTLGLQV 1117 Query: 421 REPGLLSSAPQRPVP 435 P L + +R VP Sbjct: 1118 HLPHL--TVGERAVP 1130 Score = 37.0 bits (84), Expect = 0.038 Identities = 77/252 (30%), Positives = 91/252 (36%), Gaps = 37/252 (14%) Query: 43 GGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQG--GDGRWQRRQRGHGGRRGLNGH 100 GGGR AALA R G RV G G+GR GHGG R G Sbjct: 223 GGGRLVAPSRADTHAALAA--FPERDIFHGGRVVALGVVGEGR------GHGGDR--RGG 272 Query: 101 GDGGQRLARRVAQRLQRHAVGAVVATR------HGDGGGRVDHAGGAIHVWPAGAQRAAH 154 G+G +A R+ +GA V R G + H +H +RA H Sbjct: 273 GEGLGTVAAAAPLRVCADDLGAAVGVRGLAGLQEGLDSRHLLHEAQPLH----ARRRAGH 328 Query: 155 GSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQ 214 G RL G G HL ++ G RG Q GG G Q Sbjct: 329 AGSFWLR--GGRDRLRRGGGHTKSHLGVV--TIVPGR-----RGRAAGGQERGGRGRRRQ 379 Query: 215 VRARGRQRAEPQLGLL-LQVLRRVGWLAGRQVVGLKHLEALAAP-QEAAVLEHVPAAWVQ 272 RGR++A P L + + VL G L R L H P Q A H PAA Q Sbjct: 380 QGRRGRRQAGPGLAKVDVDVL--AGALGLRWQWVLVHAGQAGQPLQGQARGPHRPAALAQ 437 Query: 273 RPEAALAWLVRP 284 EA A RP Sbjct: 438 --EALRAAAARP 447 Score = 35.4 bits (80), Expect = 0.11 Identities = 85/305 (27%), Positives = 94/305 (30%), Gaps = 106/305 (34%) Query: 17 KASEVVGRRTRGGVGSC---GSVHRHRVQGGGRA-----------GERFAGGGGAALAGG 62 +A + RR G GS G R R +GGG G R GG G Sbjct: 316 EAQPLHARRRAGHAGSFWLRGGRDRLR-RGGGHTKSHLGVVTIVPGRRGRAAGGQERGG- 373 Query: 63 CLRGRGAERGRRVREQGGDG---------------RWQ---------------------- 85 RGR ++GRR R Q G G RWQ Sbjct: 374 --RGRRRQQGRRGRRQAGPGLAKVDVDVLAGALGLRWQWVLVHAGQAGQPLQGQARGPHR 431 Query: 86 -----------RRQRGHGGR----RGLNGHG-DGGQRLA------RRVAQRLQ------- 116 R HG R RGL G G +G RLA R LQ Sbjct: 432 PAALAQEALRAAAARPHGRRHYRVRGLRGAGPEGAGRLAGPWRGLRLQTLLLQDAPHGGA 491 Query: 117 -RHAVGAVVATRHGD----GGGRVDHAGGAIHVWPAGAQRAAH--GSQLVGERVGSGH-- 167 H + AV AT G G G V AG A PAG Q G G+RV GH Sbjct: 492 HEHVLVAVPATGVGGLVGAGQGAVAAAGNAPERLPAGVQGCGEEVGRGARGDRVAGGHVE 551 Query: 168 -----------RLHGGEGQPPR-HLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGHLWQV 215 LHG G P H+ L G L A R GG W Sbjct: 552 VVPVGQQLAICMLHGQLGTAPHAHVPTVLGGALGGRAGLVAAPARRECPARRRGG-CWPR 610 Query: 216 RARGR 220 R R R Sbjct: 611 RPRRR 615 Score = 35.0 bits (79), Expect = 0.14 Identities = 63/198 (31%), Positives = 70/198 (35%), Gaps = 59/198 (29%) Query: 15 PGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAER--- 71 PG+ G + RGG G R R QG R G R AG G A + L G R Sbjct: 359 PGRRGRAAGGQERGGRG------RRRQQG--RRGRRQAGPGLAKVDVDVLAGALGLRWQW 410 Query: 72 -----GRRVREQGGDGRWQRRQ-------------RGHGGR----RGLNGHG-DGGQRLA 108 G+ + G R R R HG R RGL G G +G RLA Sbjct: 411 VLVHAGQAGQPLQGQARGPHRPAALAQEALRAAAARPHGRRHYRVRGLRGAGPEGAGRLA 470 Query: 109 ------RRVAQRLQ--------RHAVGAVVATRHGD----GGGRVDHAGGAIHVWPAGAQ 150 R LQ H + AV AT G G G V AG A PAG Q Sbjct: 471 GPWRGLRLQTLLLQDAPHGGAHEHVLVAVPATGVGGLVGAGQGAVAAAGNAPERLPAGVQ 530 Query: 151 RAAHGSQLVGERVGSGHR 168 GE VG G R Sbjct: 531 GC-------GEEVGRGAR 541 >gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] Length = 589 Score = 52.4 bits (124), Expect = 9e-07 Identities = 56/174 (32%), Positives = 67/174 (38%), Gaps = 16/174 (9%) Query: 3 GGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62 GGE G+ + G G R+ GG G R GGG +G+R GG G +GG Sbjct: 397 GGERGYRGRGGRGGDRGGYGGDRSGGGYGG------DRSSGGGYSGDRSGGGYGGDRSGG 450 Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGA 122 G G +RG G G R G+GG RG G GG R R G Sbjct: 451 ---GYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG- 506 Query: 123 VVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVG--SGHRLHGGEG 174 R G GG R + G G + GS G+R G G R GG G Sbjct: 507 --GDRGGYGGDRGGYGGDRSRGGYGGDR--GGGSGYGGDRSGGYGGDRSGGGYG 556 Score = 34.7 bits (78), Expect = 0.19 Identities = 35/109 (32%), Positives = 45/109 (41%), Gaps = 10/109 (9%) Query: 3 GGEWGWGRQDWEPGKASEVVGRR-----TRGGVGSCGSVHRHRVQGGGRAGERFAGGGGA 57 GG +G R + + G R RGG G G + GG G+R GG G Sbjct: 473 GGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGG 530 Query: 58 ALAGGCLRGRGAER-GRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQ 105 GG G G +R G ++ G G R G+GG RG G GG+ Sbjct: 531 DRGGG--SGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGR 577 Score = 32.3 bits (72), Expect = 0.93 Identities = 29/92 (31%), Positives = 36/92 (39%), Gaps = 16/92 (17%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61 GG G+G G G R+RGG G R G G G+R G GG G Sbjct: 506 GGDRGGYG------GDRGGYGGDRSRGGYGG------DRGGGSGYGGDRSGGYGGDRSGG 553 Query: 62 GC----LRGRGAERGRRVREQGGDGRWQRRQR 89 G G G +RG + GG ++ QR Sbjct: 554 GYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQR 585 Score = 32.0 bits (71), Expect = 1.2 Identities = 49/171 (28%), Positives = 55/171 (32%), Gaps = 32/171 (18%) Query: 27 RGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG-------GCLRGRGAERG------- 72 RGG GS R +GG R F G GG +G C A R Sbjct: 323 RGG----GSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNE 378 Query: 73 ---RRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRL------QRHAVGAV 123 R GGD R RG+GG RG G G G R R + G Sbjct: 379 PRPEDSRPSGGDFRG----RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGY 434 Query: 124 VATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEG 174 R G G G D +GG G G G+R G GG G Sbjct: 435 SGDRSGGGYGG-DRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYG 484 >gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] Length = 592 Score = 52.4 bits (124), Expect = 9e-07 Identities = 56/174 (32%), Positives = 67/174 (38%), Gaps = 16/174 (9%) Query: 3 GGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62 GGE G+ + G G R+ GG G R GGG +G+R GG G +GG Sbjct: 400 GGERGYRGRGGRGGDRGGYGGDRSGGGYGG------DRSSGGGYSGDRSGGGYGGDRSGG 453 Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGA 122 G G +RG G G R G+GG RG G GG R R G Sbjct: 454 ---GYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG- 509 Query: 123 VVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVG--SGHRLHGGEG 174 R G GG R + G G + GS G+R G G R GG G Sbjct: 510 --GDRGGYGGDRGGYGGDRSRGGYGGDR--GGGSGYGGDRSGGYGGDRSGGGYG 559 Score = 34.7 bits (78), Expect = 0.19 Identities = 35/109 (32%), Positives = 45/109 (41%), Gaps = 10/109 (9%) Query: 3 GGEWGWGRQDWEPGKASEVVGRR-----TRGGVGSCGSVHRHRVQGGGRAGERFAGGGGA 57 GG +G R + + G R RGG G G + GG G+R GG G Sbjct: 476 GGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGG 533 Query: 58 ALAGGCLRGRGAER-GRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQ 105 GG G G +R G ++ G G R G+GG RG G GG+ Sbjct: 534 DRGGG--SGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGR 580 Score = 32.3 bits (72), Expect = 0.93 Identities = 29/92 (31%), Positives = 36/92 (39%), Gaps = 16/92 (17%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61 GG G+G G G R+RGG G R G G G+R G GG G Sbjct: 509 GGDRGGYG------GDRGGYGGDRSRGGYGG------DRGGGSGYGGDRSGGYGGDRSGG 556 Query: 62 GC----LRGRGAERGRRVREQGGDGRWQRRQR 89 G G G +RG + GG ++ QR Sbjct: 557 GYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQR 588 Score = 32.0 bits (71), Expect = 1.2 Identities = 49/171 (28%), Positives = 55/171 (32%), Gaps = 32/171 (18%) Query: 27 RGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG-------GCLRGRGAERG------- 72 RGG GS R +GG R F G GG +G C A R Sbjct: 326 RGG----GSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNE 381 Query: 73 ---RRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRL------QRHAVGAV 123 R GGD R RG+GG RG G G G R R + G Sbjct: 382 PRPEDSRPSGGDFRG----RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGY 437 Query: 124 VATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEG 174 R G G G D +GG G G G+R G GG G Sbjct: 438 SGDRSGGGYGG-DRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYG 487 >gi|239755920 PREDICTED: hypothetical protein XP_002344746 [Homo sapiens] Length = 600 Score = 49.7 bits (117), Expect = 6e-06 Identities = 78/257 (30%), Positives = 96/257 (37%), Gaps = 56/257 (21%) Query: 16 GKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGR-- 73 G+ + V R R GVG+ H VQ G AGGC RG G G Sbjct: 298 GEQTAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGCRRGGGRRCGHVR 349 Query: 74 -RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRLQRHAVGAVVATR 127 VREQ +RGHG G L G GG+ R Q L+R G Sbjct: 350 VGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSLRRSGRG------ 393 Query: 128 HGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDV 187 HG G D GG R G+ G H GEG P L +++ Sbjct: 394 HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGAPHGKLAGVQEER 438 Query: 188 LDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQVLRRVGWLAGRQ 244 + E +L +ARG A Q G L QVR R R E + GLL + R+ L GR+ Sbjct: 439 VPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLARERARLFHL-GRR 492 Query: 245 VVGLKHLEALAAPQEAA 261 AL Q A+ Sbjct: 493 CALANRAPALLRAQAAS 509 Score = 37.4 bits (85), Expect = 0.029 Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%) Query: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101 QG G GER GGAA+ R R R QGGD Q G RG G Sbjct: 249 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 294 Query: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149 GG V R R VGAV R HG + G V AGG HV Sbjct: 295 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 353 Query: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180 ++A+ HG L G+ V GG G+P + L Sbjct: 354 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 387 Score = 37.0 bits (84), Expect = 0.038 Identities = 47/144 (32%), Positives = 53/144 (36%), Gaps = 23/144 (15%) Query: 14 EPGKASEVVGRRTRGGVGSCGSVH-------RHRVQGGGRAGE----RFAGGGGAALAGG 62 E G A G RGG CG V R G G+ G GG G Sbjct: 326 EEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQ 385 Query: 63 CLR--GRGAERGRRVREQGGDGRWQRRQRG------HGGRRGLNGHGDGGQRLARRVAQR 114 LR GRG RG + R+ GG R R Q G H G +G G Q V + Sbjct: 386 SLRRSGRGHGRGIQARDTGGGPR-NRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEEL 444 Query: 115 LQRHAVGAVVATRHGDG---GGRV 135 L R A G A + G GGRV Sbjct: 445 LARQARGEAEARQGALGQVRGGRV 468 Score = 34.7 bits (78), Expect = 0.19 Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%) Query: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155 G GHG GG+R V R + H G GG+ GG V G + HG Sbjct: 247 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 293 Query: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211 Q GE+ + H G QP H V + +G V A G R GGG Sbjct: 294 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 344 Query: 212 LWQVRARGRQRA 223 VR R++A Sbjct: 345 CGHVRVGVREQA 356 >gi|239750438 PREDICTED: hypothetical protein [Homo sapiens] Length = 510 Score = 49.7 bits (117), Expect = 6e-06 Identities = 78/257 (30%), Positives = 96/257 (37%), Gaps = 56/257 (21%) Query: 16 GKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGR-- 73 G+ + V R R GVG+ H VQ G AGGC RG G G Sbjct: 155 GEQTAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGCRRGGGRRCGHVR 206 Query: 74 -RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRLQRHAVGAVVATR 127 VREQ +RGHG G L G GG+ R Q L+R G Sbjct: 207 VGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSLRRSGRG------ 250 Query: 128 HGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDV 187 HG G D GG R G+ G H GEG P L +++ Sbjct: 251 HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGAPHGKLAGVQEER 295 Query: 188 LDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQVLRRVGWLAGRQ 244 + E +L +ARG A Q G L QVR R R E + GLL + R+ L GR+ Sbjct: 296 VPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLARERARLFHL-GRR 349 Query: 245 VVGLKHLEALAAPQEAA 261 AL Q A+ Sbjct: 350 CALANRAPALLRAQAAS 366 Score = 37.4 bits (85), Expect = 0.029 Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%) Query: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101 QG G GER GGAA+ R R R QGGD Q G RG G Sbjct: 106 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 151 Query: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149 GG V R R VGAV R HG + G V AGG HV Sbjct: 152 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 210 Query: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180 ++A+ HG L G+ V GG G+P + L Sbjct: 211 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 244 Score = 37.0 bits (84), Expect = 0.038 Identities = 47/144 (32%), Positives = 53/144 (36%), Gaps = 23/144 (15%) Query: 14 EPGKASEVVGRRTRGGVGSCGSVH-------RHRVQGGGRAGE----RFAGGGGAALAGG 62 E G A G RGG CG V R G G+ G GG G Sbjct: 183 EEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQ 242 Query: 63 CLR--GRGAERGRRVREQGGDGRWQRRQRG------HGGRRGLNGHGDGGQRLARRVAQR 114 LR GRG RG + R+ GG R R Q G H G +G G Q V + Sbjct: 243 SLRRSGRGHGRGIQARDTGGGPR-NRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEEL 301 Query: 115 LQRHAVGAVVATRHGDG---GGRV 135 L R A G A + G GGRV Sbjct: 302 LARQARGEAEARQGALGQVRGGRV 325 Score = 34.7 bits (78), Expect = 0.19 Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%) Query: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155 G GHG GG+R V R + H G GG+ GG V G + HG Sbjct: 104 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 150 Query: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211 Q GE+ + H G QP H V + +G V A G R GGG Sbjct: 151 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 201 Query: 212 LWQVRARGRQRA 223 VR R++A Sbjct: 202 CGHVRVGVREQA 213 >gi|239744740 PREDICTED: hypothetical protein XP_002343259 [Homo sapiens] Length = 457 Score = 49.7 bits (117), Expect = 6e-06 Identities = 78/257 (30%), Positives = 96/257 (37%), Gaps = 56/257 (21%) Query: 16 GKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGR-- 73 G+ + V R R GVG+ H VQ G AGGC RG G G Sbjct: 155 GEQTAAVRDRHRDGVGAVAQPRAHGVQ--------IEEGVAVHRAGGCRRGGGRRCGHVR 206 Query: 74 -RVREQGGDGRWQRRQRGHGGRRG-----LNGHGDGGQRLARRVAQRLQRHAVGAVVATR 127 VREQ +RGHG G L G GG+ R Q L+R G Sbjct: 207 VGVREQAS-------ERGHGQALGGQDVLLEVEGQGGR---GRPGQSLRRSGRG------ 250 Query: 128 HGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDV 187 HG G D GG R G+ G H GEG P L +++ Sbjct: 251 HGRGIQARDTGGGP-------RNRGQEGTHASGR--------HAGEGAPHGKLAGVQEER 295 Query: 188 LDGEGVL--EARGLRHAAQVVGGGGHLWQVR-ARGRQRAEPQLGLLLQVLRRVGWLAGRQ 244 + E +L +ARG A Q G L QVR R R E + GLL + R+ L GR+ Sbjct: 296 VPVEELLARQARGEAEARQ-----GALGQVRGGRVRLHRERREGLLARERARLFHL-GRR 349 Query: 245 VVGLKHLEALAAPQEAA 261 AL Q A+ Sbjct: 350 CALANRAPALLRAQAAS 366 Score = 37.4 bits (85), Expect = 0.029 Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 30/154 (19%) Query: 42 QGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHG 101 QG G GER GGAA+ R R R QGGD Q G RG G Sbjct: 106 QGHGAGGER----GGAAVE---FRARVHCHRGRAGGQGGDFAVQ-------GPRGRRHGG 151 Query: 102 DGGQRLARRVAQRLQRHAVGAVVATR-HG---DGGGRVDHAGGAI--------HVWPAGA 149 GG V R R VGAV R HG + G V AGG HV Sbjct: 152 QGGGEQTAAVRDR-HRDGVGAVAQPRAHGVQIEEGVAVHRAGGCRRGGGRRCGHVRVGVR 210 Query: 150 QRAA---HGSQLVGERVGSGHRLHGGEGQPPRHL 180 ++A+ HG L G+ V GG G+P + L Sbjct: 211 EQASERGHGQALGGQDVLLEVEGQGGRGRPGQSL 244 Score = 37.0 bits (84), Expect = 0.038 Identities = 47/144 (32%), Positives = 53/144 (36%), Gaps = 23/144 (15%) Query: 14 EPGKASEVVGRRTRGGVGSCGSVH-------RHRVQGGGRAGE----RFAGGGGAALAGG 62 E G A G RGG CG V R G G+ G GG G Sbjct: 183 EEGVAVHRAGGCRRGGGRRCGHVRVGVREQASERGHGQALGGQDVLLEVEGQGGRGRPGQ 242 Query: 63 CLR--GRGAERGRRVREQGGDGRWQRRQRG------HGGRRGLNGHGDGGQRLARRVAQR 114 LR GRG RG + R+ GG R R Q G H G +G G Q V + Sbjct: 243 SLRRSGRGHGRGIQARDTGGGPR-NRGQEGTHASGRHAGEGAPHGKLAGVQEERVPVEEL 301 Query: 115 LQRHAVGAVVATRHGDG---GGRV 135 L R A G A + G GGRV Sbjct: 302 LARQARGEAEARQGALGQVRGGRV 325 Score = 34.7 bits (78), Expect = 0.19 Identities = 40/132 (30%), Positives = 50/132 (37%), Gaps = 26/132 (19%) Query: 96 GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG 155 G GHG GG+R V R + H G GG+ GG V G + HG Sbjct: 104 GRQGHGAGGERGGAAVEFRARVHC-------HRGRAGGQ----GGDFAV--QGPRGRRHG 150 Query: 156 SQLVGERVGSGHRLH----GGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGGH 211 Q GE+ + H G QP H V + +G V A G R GGG Sbjct: 151 GQGGGEQTAAVRDRHRDGVGAVAQPRAHGV----QIEEGVAVHRAGGCRR-----GGGRR 201 Query: 212 LWQVRARGRQRA 223 VR R++A Sbjct: 202 CGHVRVGVREQA 213 >gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo sapiens] Length = 940 Score = 44.3 bits (103), Expect = 2e-04 Identities = 60/201 (29%), Positives = 65/201 (32%), Gaps = 43/201 (21%) Query: 24 RRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVRE--QGGD 81 R RGG G + GGG GGGG G G G G R E GG Sbjct: 723 RGARGGRSGGGPPNGRGGPGGG-----MVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGM 777 Query: 82 GRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGA 141 G R G GG G G GG R G GGG +G Sbjct: 778 GSGHRPHEGPGGSMG----GGGGHR-------------------PHEGPGGGISGGSGHR 814 Query: 142 IHVWPAGAQRAAHGSQLVGERVGS-----GHRLHGGEGQPPRHLVFPRDDVLDGEGVLEA 196 H P G A G + GS GHR H G G H P D + G + Sbjct: 815 PHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHD--VPGHRGHDH 872 Query: 197 RG------LRHAAQVVGGGGH 211 RG H GGGGH Sbjct: 873 RGPPPHEHRGHDGPGHGGGGH 893 Score = 40.4 bits (93), Expect = 0.003 Identities = 50/185 (27%), Positives = 60/185 (32%), Gaps = 40/185 (21%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61 GG G Q + PG + G GG G R G+ F G G + G Sbjct: 632 GGPGGPKGMQHFPPGPGGPMPG--PHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRG 689 Query: 62 GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGR---------RGLNGHGDGGQRLARRVA 112 G +RG G G + R + G GG RG G G Sbjct: 690 GPMRGGPGP---------GPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSG--------- 731 Query: 113 QRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHG---SQLVGERVGSGHRL 169 G R G GGG V G H P G + G + G +GSGHR Sbjct: 732 --------GGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRP 783 Query: 170 HGGEG 174 H G G Sbjct: 784 HEGPG 788 >gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo sapiens] Length = 594 Score = 44.3 bits (103), Expect = 2e-04 Identities = 125/487 (25%), Positives = 160/487 (32%), Gaps = 135/487 (27%) Query: 44 GGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQG-------GDGRWQRRQRGHG---- 92 GG+AG G G GC R + RG R G G W R++ HG Sbjct: 33 GGQAGHPVVGDTGQ-FERGCARRHRSPRGHRHAVPGPRLQRALGGQAWAGRRQLHGFMLY 91 Query: 93 ------GRRG---LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIH 143 G RG + G G GG RLQ +VA G G G +DH+G + Sbjct: 92 SGQQRDGHRGGHDVGGRGGGG---------RLQ------LVAGALGLGAGVLDHSGLRVA 136 Query: 144 VWPAGAQR----AAHGSQLVGE--RVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEAR 197 V A + A H + E RV L G G+P R V +G+ +LEA Sbjct: 137 VGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPAR--------VAEGQDLLEAG 188 Query: 198 GLRHAAQVVG----GGGHLWQVRARGRQR-----------------AEPQLGLLLQVLRR 236 G A Q+ G + +V A G Q E Q LL+Q + Sbjct: 189 GRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGLALDHDGHIAVEAQQALLVQAAQH 248 Query: 237 ----------------------VGWLAGRQVVGLKHLEALAAPQEAAVLEHVPAAWV-QR 273 +G G + GL +L + A AA H P Q Sbjct: 249 CVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAA----AAAGRHCPLRLAGQA 304 Query: 274 PEAALAWLVRPPRDLDEAVVEGEVVA-----------------QTVLPALRVLPVVGEAV 316 P A P E G A Q++ L V P G V Sbjct: 305 PRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARV 364 Query: 317 HD--ELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAA-GPRHLLPRPLLALGPRG 373 + E V +R HL G+ R+G+ +R G R LG RG Sbjct: 365 GEAREAVTTHERAHL------DREGEARARLGQAAAQMRREGWGAR-------AKLGGRG 411 Query: 374 PADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTRREPGLLSSAPQRP 433 C G G + R R AA R L RA +GS R G A + Sbjct: 412 V--CGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGR-- 467 Query: 434 VPPGPRR 440 VP G RR Sbjct: 468 VPSGGRR 474 >gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo sapiens] Length = 594 Score = 44.3 bits (103), Expect = 2e-04 Identities = 125/487 (25%), Positives = 160/487 (32%), Gaps = 135/487 (27%) Query: 44 GGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQG-------GDGRWQRRQRGHG---- 92 GG+AG G G GC R + RG R G G W R++ HG Sbjct: 33 GGQAGHPVVGDTGQ-FERGCARRHRSPRGHRHAVPGPRLQRALGGQAWAGRRQLHGFMLY 91 Query: 93 ------GRRG---LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIH 143 G RG + G G GG RLQ +VA G G G +DH+G + Sbjct: 92 SGQQRDGHRGGHDVGGRGGGG---------RLQ------LVAGALGLGAGVLDHSGLRVA 136 Query: 144 VWPAGAQR----AAHGSQLVGE--RVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEAR 197 V A + A H + E RV L G G+P R V +G+ +LEA Sbjct: 137 VGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPAR--------VAEGQDLLEAG 188 Query: 198 GLRHAAQVVG----GGGHLWQVRARGRQR-----------------AEPQLGLLLQVLRR 236 G A Q+ G + +V A G Q E Q LL+Q + Sbjct: 189 GRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGLALDHDGHIAVEAQQALLVQAAQH 248 Query: 237 ----------------------VGWLAGRQVVGLKHLEALAAPQEAAVLEHVPAAWV-QR 273 +G G + GL +L + A AA H P Q Sbjct: 249 CVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAA----AAAGRHCPLRLAGQA 304 Query: 274 PEAALAWLVRPPRDLDEAVVEGEVVA-----------------QTVLPALRVLPVVGEAV 316 P A P E G A Q++ L V P G V Sbjct: 305 PRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARV 364 Query: 317 HD--ELVDLAQRQHLLGRALDGHSGQRDVRVGRLLVAVRVAA-GPRHLLPRPLLALGPRG 373 + E V +R HL G+ R+G+ +R G R LG RG Sbjct: 365 GEAREAVTTHERAHL------DREGEARARLGQAAAQMRREGWGAR-------AKLGGRG 411 Query: 374 PADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTRREPGLLSSAPQRP 433 C G G + R R AA R L RA +GS R G A + Sbjct: 412 V--CGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGR-- 467 Query: 434 VPPGPRR 440 VP G RR Sbjct: 468 VPSGGRR 474 >gi|109452587 family with sequence similarity 98, member B isoform 1 [Homo sapiens] Length = 433 Score = 44.3 bits (103), Expect = 2e-04 Identities = 38/105 (36%), Positives = 40/105 (38%), Gaps = 5/105 (4%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61 GGG GWG G+ G RGG G G GGG G + GGGG G Sbjct: 332 GGGRGGWGGGGGGGGRGGGG-GGGGRGGWGGGGGGWG----GGGGGGGGWGGGGGGGRGG 386 Query: 62 GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQR 106 RG RG G GR G GG G G G GG R Sbjct: 387 FQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYR 431 Score = 39.3 bits (90), Expect = 0.008 Identities = 41/135 (30%), Positives = 47/135 (34%), Gaps = 37/135 (27%) Query: 40 RVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNG 99 R +GGG G GGGG GG G G RG GG G W G GG G G Sbjct: 328 RQEGGGGRGGWGGGGGGGGRGGG---GGGGGRG---GWGGGGGGWGGGGGGGGGWGGGGG 381 Query: 100 HGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLV 159 G GG + GD GGR + G R +G + Sbjct: 382 GGRGGFQ--------------------GRGDYGGRGGYGG-----------RGGYGGRGY 410 Query: 160 GERVGSGHRLHGGEG 174 G+ G G GG G Sbjct: 411 GDPYGGGGGGGGGGG 425 Score = 38.9 bits (89), Expect = 0.010 Identities = 38/115 (33%), Positives = 42/115 (36%), Gaps = 16/115 (13%) Query: 64 LRGRGAERGRRVREQGGDGR----WQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHA 119 L GR +RG R E WQ+RQ G GGR G G G GG R Sbjct: 301 LMGRVPDRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGR----------GGG 350 Query: 120 VGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEG 174 G G GGG GG W G G Q G+ G G +GG G Sbjct: 351 GGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGG--YGGRG 403 >gi|47132620 keratin 2 [Homo sapiens] Length = 639 Score = 43.1 bits (100), Expect = 5e-04 Identities = 35/108 (32%), Positives = 44/108 (40%), Gaps = 16/108 (14%) Query: 3 GGEWGWGRQD---WEPGKASEVVGRR---TRGGVGSCGSVHRHRVQGGGRAGERFAGGGG 56 GG G G + G +S G R +RGG G GS+ GG +G R+ GGG Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG 578 Query: 57 AALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGG 104 + GG + G G G GG R GG G+G GG Sbjct: 579 S--KGGSISGGGYGSGGGKHSSGGGSR--------GGSSSGGGYGSGG 616 Score = 35.8 bits (81), Expect = 0.084 Identities = 33/103 (32%), Positives = 40/103 (38%), Gaps = 11/103 (10%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61 GGG G+G + ++ + GG G G+ +GGG G GGG G Sbjct: 54 GGG--GFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGG 111 Query: 62 GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGG 104 G G G G R GG G G GG G G G GG Sbjct: 112 GF--GGGGFGGGRFGGFGGPG-------GVGGLGGPGGFGPGG 145 Score = 33.5 bits (75), Expect = 0.42 Identities = 39/123 (31%), Positives = 43/123 (34%), Gaps = 29/123 (23%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERF---------- 51 G G G G + + G A VV +R S + RH GGG G F Sbjct: 11 GRGGGGGGFRGFSSGSA--VVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGG 68 Query: 52 --------AGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDG 103 AGGGG A G GRG G GG G GG G G G G Sbjct: 69 TKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSG-------FSGG--GFGGGGFG 119 Query: 104 GQR 106 G R Sbjct: 120 GGR 122 Score = 32.0 bits (71), Expect = 1.2 Identities = 33/118 (27%), Positives = 42/118 (35%), Gaps = 6/118 (5%) Query: 45 GRAGERFAGGGGAALAGGCLRGRGA-ERGRRVREQGG---DGRWQRRQRGHGGRRGLNGH 100 G +G R + GG +G G G + G R GG G G GGR G G Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG 578 Query: 101 GDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQL 158 GG +H+ G GGG GG+ V G+ A GS + Sbjct: 579 SKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSV--KGSSGEAFGSSV 634 >gi|7710145 methyl-CpG binding domain protein 2 testis-specific isoform [Homo sapiens] Length = 302 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/85 (41%), Positives = 39/85 (45%), Gaps = 16/85 (18%) Query: 27 RGGVGSC------GSVHRHRVQGGGRAGERF--AGGGGAALAGGCLRGRGAERGRRVREQ 78 +GG GS V R +GGGR R+ AG GG G C RGRG RGR Sbjct: 34 QGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGG----GVCGRGRGRGRGR----G 85 Query: 79 GGDGRWQRRQRGHGGRRGLNGHGDG 103 G GR + R R G GL G G G Sbjct: 86 RGRGRGRGRGRPPSGGSGLGGDGGG 110 Score = 33.1 bits (74), Expect = 0.55 Identities = 36/105 (34%), Positives = 44/105 (41%), Gaps = 11/105 (10%) Query: 43 GGGRAGERFA---GGGGAALAGGCLRG---RGAERGRRVREQGGDGRWQRRQRGHGGRRG 96 GG AG A GG G+ALA + G GA G R G GRW++ RG G Sbjct: 22 GGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGR-----GRGRWKQAGRGGGVCGR 76 Query: 97 LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGA 141 G G G R R R + + G+ + G GG GGA Sbjct: 77 GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121 Score = 30.4 bits (67), Expect = 3.5 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 4/71 (5%) Query: 2 GGGEWGWGRQDW-EPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 GGG GR W + G+ V GR G G R R +G +G GG G Sbjct: 56 GGGR---GRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCG 112 Query: 61 GGCLRGRGAER 71 GG G GA R Sbjct: 113 GGGSGGGGAPR 123 >gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo sapiens] Length = 411 Score = 42.4 bits (98), Expect = 0.001 Identities = 35/85 (41%), Positives = 39/85 (45%), Gaps = 16/85 (18%) Query: 27 RGGVGSC------GSVHRHRVQGGGRAGERF--AGGGGAALAGGCLRGRGAERGRRVREQ 78 +GG GS V R +GGGR R+ AG GG G C RGRG RGR Sbjct: 34 QGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGG----GVCGRGRGRGRGR----G 85 Query: 79 GGDGRWQRRQRGHGGRRGLNGHGDG 103 G GR + R R G GL G G G Sbjct: 86 RGRGRGRGRGRPPSGGSGLGGDGGG 110 Score = 33.1 bits (74), Expect = 0.55 Identities = 36/105 (34%), Positives = 44/105 (41%), Gaps = 11/105 (10%) Query: 43 GGGRAGERFA---GGGGAALAGGCLRG---RGAERGRRVREQGGDGRWQRRQRGHGGRRG 96 GG AG A GG G+ALA + G GA G R G GRW++ RG G Sbjct: 22 GGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGR-----GRGRWKQAGRGGGVCGR 76 Query: 97 LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGA 141 G G G R R R + + G+ + G GG GGA Sbjct: 77 GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121 Score = 30.4 bits (67), Expect = 3.5 Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 4/71 (5%) Query: 2 GGGEWGWGRQDW-EPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 GGG GR W + G+ V GR G G R R +G +G GG G Sbjct: 56 GGGR---GRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCG 112 Query: 61 GGCLRGRGAER 71 GG G GA R Sbjct: 113 GGGSGGGGAPR 123 >gi|119395750 keratin 1 [Homo sapiens] Length = 644 Score = 42.0 bits (97), Expect = 0.001 Identities = 35/103 (33%), Positives = 38/103 (36%), Gaps = 12/103 (11%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61 GGG +G G + G S G GG GS GS GGG G GGG + Sbjct: 521 GGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGS 580 Query: 62 GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGG 104 G G G R GG G G G RG G GG Sbjct: 581 GSSSG-----GYRGGSGGGGG-------GSSGGRGSGGGSSGG 611 Score = 37.0 bits (84), Expect = 0.038 Identities = 36/118 (30%), Positives = 43/118 (36%), Gaps = 9/118 (7%) Query: 28 GGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRR 87 GG GS GS + GGG G GGGG G G+ G GG G Sbjct: 523 GGYGSGGSSYG---SGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYG 579 Query: 88 Q-RGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHV 144 GG RG +G G GG R ++G G G V +GG+ V Sbjct: 580 SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGG-----RGSSSGGVKSSGGSSSV 632 Score = 35.8 bits (81), Expect = 0.084 Identities = 29/86 (33%), Positives = 35/86 (40%), Gaps = 12/86 (13%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGG------ 55 G G +G G + G S G GG G GS GG R G GGG Sbjct: 548 GRGSYGSGGSSYGSGGGSYGSG----GGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRG 603 Query: 56 -GAALAGGCLRGRGAERGRRVREQGG 80 G +GG + GRG+ G V+ GG Sbjct: 604 SGGGSSGGSIGGRGSSSG-GVKSSGG 628 Score = 32.7 bits (73), Expect = 0.71 Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 15/104 (14%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGG-GGAALA 60 GGG +G G G R+ +G S+ +GGGR G F GG GG Sbjct: 52 GGGSFGAGGG----------FGSRSLVNLGGSKSISISVARGGGR-GSGFGGGYGGGGFG 100 Query: 61 GGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGG 104 GG G G G GG G + G GG G G G GG Sbjct: 101 GGGFGGGGFGGGG--IGGGGFGGFGSGGGGFGG-GGFGGGGYGG 141 Score = 32.0 bits (71), Expect = 1.2 Identities = 32/98 (32%), Positives = 40/98 (40%), Gaps = 20/98 (20%) Query: 23 GRRTRGGV--GSCGSVHRHR------VQGGGRAGERFA---GGGGAALAGGCLRGR---- 67 G R+ GG GS G ++ R + G G RF+ GGGG+ AGG R Sbjct: 10 GYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVN 69 Query: 68 -GAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGG 104 G + + G GR G GG G G G GG Sbjct: 70 LGGSKSISISVARGGGRGS----GFGGGYGGGGFGGGG 103 Score = 30.0 bits (66), Expect = 4.6 Identities = 20/64 (31%), Positives = 23/64 (35%), Gaps = 3/64 (4%) Query: 41 VQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGH 100 + GGG G GGGG G G G GG G + +G G G Sbjct: 512 ISGGGSRG---GGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGS 568 Query: 101 GDGG 104 G GG Sbjct: 569 GGGG 572 >gi|57864582 hornerin [Homo sapiens] Length = 2850 Score = 42.0 bits (97), Expect = 0.001 Identities = 39/147 (26%), Positives = 54/147 (36%), Gaps = 9/147 (6%) Query: 29 GVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG----GCLRGRGAERGRRVREQGGDGRW 84 G G +H+ G +G G G +G G G+ + RG R R G Sbjct: 224 GSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSS-RGERHRSSSGSSS- 281 Query: 85 QRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHV 144 Q G G R+ L GHG G R + RH G+ ++ HG G ++ H Sbjct: 282 SYGQHGSGSRQSL-GHGRQGS--GSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHY 338 Query: 145 WPAGAQRAAHGSQLVGERVGSGHRLHG 171 Q + G G SG+ HG Sbjct: 339 ESGSGQTSGFGQHESGSGQSSGYSKHG 365 Score = 37.4 bits (85), Expect = 0.029 Identities = 42/181 (23%), Positives = 64/181 (35%), Gaps = 10/181 (5%) Query: 3 GGEWGWGRQDWEPGK--ASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 G W R +E G +S + R +R G S H G+ + G ++ Sbjct: 1030 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 1089 Query: 61 G--GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118 G G G+ + G Q G G Q G G G G + R + RH Sbjct: 1090 GQHGASSGQSSSHG-----QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1144 Query: 119 AVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGG-EGQPP 177 G+ ++ G G + + G H + Q +++ G SG+ HG GQ Sbjct: 1145 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1204 Query: 178 R 178 R Sbjct: 1205 R 1205 Score = 37.4 bits (85), Expect = 0.029 Identities = 42/181 (23%), Positives = 64/181 (35%), Gaps = 10/181 (5%) Query: 3 GGEWGWGRQDWEPGKA--SEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 G W R +E G + S + R +R G S H G+ + G ++ Sbjct: 1500 GSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 1559 Query: 61 G--GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118 G G G+ + G Q G G Q G G G G + R + RH Sbjct: 1560 GQHGASSGQSSSHG-----QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1614 Query: 119 AVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGG-EGQPP 177 G+ ++ G G + + G H + Q +++ G SG+ HG GQ Sbjct: 1615 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1674 Query: 178 R 178 R Sbjct: 1675 R 1675 Score = 37.4 bits (85), Expect = 0.029 Identities = 42/181 (23%), Positives = 64/181 (35%), Gaps = 10/181 (5%) Query: 3 GGEWGWGRQDWEPGK--ASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 G W R +E G +S + R +R G S H G+ + G ++ Sbjct: 1970 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSC 2029 Query: 61 G--GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118 G G G+ + G Q G G Q G G G G + R + RH Sbjct: 2030 GQHGASSGQSSSHG-----QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2084 Query: 119 AVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGG-EGQPP 177 G+ ++ G G + + G H + Q +++ G SG+ HG GQ Sbjct: 2085 GSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2144 Query: 178 R 178 R Sbjct: 2145 R 2145 Score = 37.4 bits (85), Expect = 0.029 Identities = 42/181 (23%), Positives = 64/181 (35%), Gaps = 10/181 (5%) Query: 3 GGEWGWGRQDWEPGK--ASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 G W R +E G +S + R +R G S H G+ + G ++ Sbjct: 2440 GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC 2499 Query: 61 G--GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118 G G G+ + G Q G G Q G G G G + R + RH Sbjct: 2500 GQHGASSGQSSSHG-----QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2554 Query: 119 AVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGG-EGQPP 177 G+ ++ G G + + G H + Q +++ G SG+ HG GQ Sbjct: 2555 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 2614 Query: 178 R 178 R Sbjct: 2615 R 2615 Score = 36.6 bits (83), Expect = 0.049 Identities = 42/165 (25%), Positives = 54/165 (32%), Gaps = 33/165 (20%) Query: 3 GGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62 G G+G + G++S + G S H R G GER G++ Sbjct: 2102 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR-SGQSSRGERHGSSSGSS---- 2156 Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGA 122 R + G R+ G GR Q GH RG +G G G H Sbjct: 2157 ---SRYGQHGSGSRQSSGHGR-QGSGSGHSPSRGRHGSGSG----------HSSSHG--- 2199 Query: 123 VVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGH 167 +HG G GR G R+ H S GSGH Sbjct: 2200 ----QHGSGSGRSSSRG-------PYESRSGHSSVFGQHESGSGH 2233 Score = 36.2 bits (82), Expect = 0.065 Identities = 45/202 (22%), Positives = 64/202 (31%), Gaps = 26/202 (12%) Query: 3 GGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62 G G+G + G++S + G S H R G GER G++ G Sbjct: 2572 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR-SGQSSRGERHGSSSGSSSHYG 2630 Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQR-----GHGGRRGLNGHGDGGQRLARRVAQRLQR 117 + R+ G G+ R R GH G +G G G RL Sbjct: 2631 QHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGH 2690 Query: 118 HAVGAVVATRHGDGGGRVDHAGGAIHVWPAG-------------------AQRAAHGSQL 158 +V + G H G+ H G Q +++G + Sbjct: 2691 SSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRG 2750 Query: 159 VGERVGSGHRLHG-GEGQPPRH 179 G SG+ HG G GQ H Sbjct: 2751 SGSSQSSGYGRHGAGSGQSLSH 2772 Score = 35.8 bits (81), Expect = 0.084 Identities = 41/178 (23%), Positives = 59/178 (33%), Gaps = 6/178 (3%) Query: 3 GGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62 G G G+ G++S G R GS S +H G ++ G G+ + Sbjct: 486 GHSSGHGQHGSRSGQSSR--GERQGSSAGSSSSYGQHG-SGSRQSLGHSRHGSGSGQSPS 542 Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQR--LQRHAV 120 RGR R+ G G R G +GH G R Q +H Sbjct: 543 PSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGS 602 Query: 121 GAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177 + ++ HG G + Q ++HG G S + G G GQ P Sbjct: 603 SSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSP 660 Score = 34.7 bits (78), Expect = 0.19 Identities = 33/147 (22%), Positives = 52/147 (35%), Gaps = 7/147 (4%) Query: 35 SVHRHRVQGGGRA---GERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGH 91 S + HR G ++ G AG G + G G G+ + G W H Sbjct: 1334 SSYGHRGSGSSQSSGYGRHGAGSGQSPSRGR--HGSGSGHSSSYGQHGSGSGWSSSSGRH 1391 Query: 92 GGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQR 151 G G + G G + + +H G+ ++ + G R + + Sbjct: 1392 GSGSGQSS-GFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS 1450 Query: 152 AAHGSQLVGERVGSGHRLHG-GEGQPP 177 +++G G R GH HG G GQ P Sbjct: 1451 SSYGQHGSGSRQSLGHGQHGSGSGQSP 1477 Score = 34.7 bits (78), Expect = 0.19 Identities = 37/165 (22%), Positives = 58/165 (35%), Gaps = 16/165 (9%) Query: 26 TRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQ 85 T G SCG +H G + G G + +G +G G+ + ++G R Sbjct: 1552 TSGQSSSCG---QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 1608 Query: 86 RRQRGHG---GRRGLNGH---------GDGGQRLARRVAQRLQRHAVGAVVATRHGDGGG 133 HG GR +G G G + + +H G+ ++ +G G Sbjct: 1609 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 1668 Query: 134 RVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177 R + + + +G G R SGH G G GQ P Sbjct: 1669 RSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSP 1713 Score = 34.7 bits (78), Expect = 0.19 Identities = 33/150 (22%), Positives = 50/150 (33%), Gaps = 5/150 (3%) Query: 32 SCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGR---GAERGRRVREQGGDGRWQRRQ 88 S G H G G + G G+ RGR G+ + G W Sbjct: 1799 STGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSS 1858 Query: 89 RGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAG 148 HG G + G G + + +H G+ ++ + G R + + Sbjct: 1859 GRHGSGSGQSS-GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSS 1917 Query: 149 AQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177 +++G G R GH HG G GQ P Sbjct: 1918 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1947 Score = 34.7 bits (78), Expect = 0.19 Identities = 33/150 (22%), Positives = 50/150 (33%), Gaps = 5/150 (3%) Query: 32 SCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGR---GAERGRRVREQGGDGRWQRRQ 88 S G H G G + G G+ RGR G+ + G W Sbjct: 2269 STGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSS 2328 Query: 89 RGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAG 148 HG G + G G + + +H G+ ++ + G R + + Sbjct: 2329 GRHGSGSGQSS-GFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSS 2387 Query: 149 AQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177 +++G G R GH HG G GQ P Sbjct: 2388 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 2417 Score = 34.7 bits (78), Expect = 0.19 Identities = 37/165 (22%), Positives = 58/165 (35%), Gaps = 16/165 (9%) Query: 26 TRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQ 85 T G SCG +H G + G G + +G +G G+ + ++G R Sbjct: 2492 TSGQSSSCG---QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 2548 Query: 86 RRQRGHG---GRRGLNGH---------GDGGQRLARRVAQRLQRHAVGAVVATRHGDGGG 133 HG GR +G G G + + +H G+ ++ +G G Sbjct: 2549 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 2608 Query: 134 RVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177 R + + + +G G R SGH G G GQ P Sbjct: 2609 RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSP 2653 Score = 34.3 bits (77), Expect = 0.25 Identities = 41/175 (23%), Positives = 59/175 (33%), Gaps = 15/175 (8%) Query: 9 GRQDWEPGKASEVVGRRTRGGVGSCGSVHR---HRVQGGGRAGERFAGGGGAALAG--GC 63 GR G++S + G S H H G GR G +G G + G G Sbjct: 842 GRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHG---SGSGQSPGHGQRGS 898 Query: 64 LRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAV 123 G+ GR G R G G G GQ + +H G+ Sbjct: 899 GSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQ------SSGYTQHGSGSG 952 Query: 124 VATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177 ++ + G R + + + +++G G R GH HG G GQ P Sbjct: 953 HSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSP 1007 Score = 33.5 bits (75), Expect = 0.42 Identities = 39/186 (20%), Positives = 60/186 (32%), Gaps = 11/186 (5%) Query: 3 GGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62 G G+ + G +S + G S H + G+ + ++ G Sbjct: 356 GQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQ 415 Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHG-GRRGLNG---------HGDGGQRLARRVA 112 G G G R G Q G G GR +G G G + + Sbjct: 416 HSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHS 475 Query: 113 QRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG- 171 +H G+ ++ HG G R + + +++G G R GH HG Sbjct: 476 SGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGS 535 Query: 172 GEGQPP 177 G GQ P Sbjct: 536 GSGQSP 541 Score = 33.5 bits (75), Expect = 0.42 Identities = 43/179 (24%), Positives = 61/179 (34%), Gaps = 10/179 (5%) Query: 3 GGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRA-----GERFAGGGGA 57 G G + G S R G GS G H +G G G +G G + Sbjct: 1563 GASSGQSSSHGQHGSGSSQSSGYGRQGSGS-GQSPGHGQRGSGSRQSPSYGRHGSGSGRS 1621 Query: 58 ALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQR 117 + +G G G G E Q G G +G+G G R + + R +R Sbjct: 1622 SSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS-SGYGQHGSRSGQ--SSRGER 1678 Query: 118 HAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQ 175 H + ++R+G G + G Q + G G S H HG G G+ Sbjct: 1679 HGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGR 1737 Score = 32.7 bits (73), Expect = 0.71 Identities = 36/165 (21%), Positives = 57/165 (34%), Gaps = 16/165 (9%) Query: 26 TRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQ 85 T G SCG +H G + G G + +G +G G+ + ++G R Sbjct: 1082 TSGQSSSCG---QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQS 1138 Query: 86 RRQRGHG---GRRGLNGH---------GDGGQRLARRVAQRLQRHAVGAVVATRHGDGGG 133 HG GR +G G G + + +H G+ ++ +G G Sbjct: 1139 PSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGS 1198 Query: 134 RVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177 R + + + +G G R SGH G G G P Sbjct: 1199 RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSP 1243 Score = 32.3 bits (72), Expect = 0.93 Identities = 42/179 (23%), Positives = 60/179 (33%), Gaps = 10/179 (5%) Query: 3 GGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRA-----GERFAGGGGA 57 G G + G S R G GS G H +G G G +G G + Sbjct: 2033 GASSGQSSSHGQHGSGSSQSSGYGRQGSGS-GQSPGHGQRGSGSRQSPSYGRHGSGSGRS 2091 Query: 58 ALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQR 117 + +G G G G E Q G G +G+G G R + + R +R Sbjct: 2092 SSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHS-SGYGQHGSRSGQ--SSRGER 2148 Query: 118 HAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQ 175 H + ++R+G G + G + G G S H HG G G+ Sbjct: 2149 HGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGR 2207 Score = 32.0 bits (71), Expect = 1.2 Identities = 35/155 (22%), Positives = 49/155 (31%), Gaps = 15/155 (9%) Query: 29 GVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQ 88 G G S H G +G G G + +G G G+ R+ G R Sbjct: 681 GSGWSSSNGPHGSVSGQSSGFGHKSGSGQS-SGYSQHGSGSSHSSGYRKHGSRSGQSSRS 739 Query: 89 RGHGGRRGLNG----HGDGGQRLARRVAQ--------RLQRHAVGAVVATRHGDGGGRVD 136 HG GL+ HG G + + Q RH + ++ HG G Sbjct: 740 EQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTS 799 Query: 137 HAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG 171 + H Q + G G G G+ HG Sbjct: 800 CSSSCGHYESGSGQASGFGQHESGS--GQGYSQHG 832 Score = 31.6 bits (70), Expect = 1.6 Identities = 35/163 (21%), Positives = 56/163 (34%), Gaps = 16/163 (9%) Query: 28 GGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRR 87 G SCG +H G + G G + +G +G G+ + ++G R Sbjct: 2024 GQSSSCG---QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPS 2080 Query: 88 QRGHG---GRRGLNGH---------GDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRV 135 HG GR +G G G + + +H G+ ++ +G G R Sbjct: 2081 YGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 2140 Query: 136 DHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEGQPP 177 + + + +G G R SGH G G G P Sbjct: 2141 GQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSP 2183 Score = 30.8 bits (68), Expect = 2.7 Identities = 40/183 (21%), Positives = 61/183 (33%), Gaps = 32/183 (17%) Query: 4 GEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG-- 61 G+ G + +S G+ G S G H + G G + R G G + Sbjct: 1201 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSG--HGRQGSGSGHSPSRGRHGSGLGHSSSH 1258 Query: 62 ---GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118 G GR + RG G + + + G G + HG G + Sbjct: 1259 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ-------- 1310 Query: 119 AVGAVVATRHGDGGGR---VDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEG 174 +HG G+ D G + Q +++G + G SG+ HG G G Sbjct: 1311 -------GQHGSTSGQSSTFDQEGSST------GQSSSYGHRGSGSSQSSGYGRHGAGSG 1357 Query: 175 QPP 177 Q P Sbjct: 1358 QSP 1360 Score = 29.6 bits (65), Expect = 6.0 Identities = 39/183 (21%), Positives = 60/183 (32%), Gaps = 32/183 (17%) Query: 4 GEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG-- 61 G+ G + ++S G+ G S G H + G G++ R G G + Sbjct: 1671 GQSSRGERHGSSSRSSSRYGQHGSGSRQSSG--HGRQGSGSGQSPSRGRHGSGLGHSSSH 1728 Query: 62 ---GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRH 118 G GR + RG G + + + G G + HG G + Sbjct: 1729 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ-------- 1780 Query: 119 AVGAVVATRHGDGGGR---VDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHG-GEG 174 +HG G+ D G + Q ++HG G S + G G G Sbjct: 1781 -------GQHGSTSGQSSTFDQEGSST------GQSSSHGQHGSGSSQSSSYGQQGSGSG 1827 Query: 175 QPP 177 Q P Sbjct: 1828 QSP 1830 Score = 29.3 bits (64), Expect = 7.9 Identities = 44/190 (23%), Positives = 60/190 (31%), Gaps = 20/190 (10%) Query: 2 GGGEWGWGR-QDWEPGKASEVVGRRTRGGVGSCGSVH-----RHRVQGGGRAGERFAGGG 55 G G+ G G Q G+ GR + G GS + H +G G G Sbjct: 425 GHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSG 484 Query: 56 GAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHG-GRRGLNGHGDGGQRLARRVAQR 114 +G G + + R QG HG G R GH G + + Sbjct: 485 SGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPS 544 Query: 115 LQRHAVGAVVATR---HGDGGGRVD----------HAGGAIHVWPAGAQRAAHGSQLVGE 161 RH G+ ++ HG G GR H+ G H Q + +G Sbjct: 545 RGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSS 604 Query: 162 RVGSGHRLHG 171 S H HG Sbjct: 605 GHSSTHGQHG 614 >gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] Length = 819 Score = 42.0 bits (97), Expect = 0.001 Identities = 53/191 (27%), Positives = 68/191 (35%), Gaps = 37/191 (19%) Query: 6 WGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLR 65 W G++D + + G +RG G + R Q AG AA G Sbjct: 633 WRRGQKDAAAAEKAWATGATSRGSGGK-----QPRWQKPAAAGSE---SSAAAAVGQEAE 684 Query: 66 GRGAERGRRVREQGGDGR--------WQRR--------QRGHGGRRGLNGHGDGGQRLAR 109 R R RR + +G G+ WQRR RG GG + G GG + +R Sbjct: 685 ARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKS---RGSGGAK-SR 740 Query: 110 RVAQRLQRHAVGAVVATRHGDGGGRVDHAGGA-----IHVWPAGAQRAAHGSQLVGERVG 164 R A + HG GG + GGA AG Q+AA RV Sbjct: 741 GSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKAAAAGGKKPPRVK 800 Query: 165 SGHRLHGGEGQ 175 S GG GQ Sbjct: 801 S----RGGRGQ 807 Score = 33.1 bits (74), Expect = 0.55 Identities = 34/138 (24%), Positives = 51/138 (36%), Gaps = 24/138 (17%) Query: 25 RTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGA-------ERGRRVRE 77 ++RGG G + R +G + + A GA G +GR RG ++ Sbjct: 436 KSRGGKSRSGGGKKPRRRG--QKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKS 493 Query: 78 QGGDGRWQRRQRGH--GGRRGLNGHGDGGQRLARRV-------------AQRLQRHAVGA 122 G W+R Q+ G + G G++ RR ++ QR A Sbjct: 494 HSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVA 553 Query: 123 VVATRHGDGGGRVDHAGG 140 AT HG GG + GG Sbjct: 554 AGATSHGGGGNKQSRGGG 571 Score = 32.3 bits (72), Expect = 0.93 Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 11/129 (8%) Query: 10 RQDWEPGKA-SEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERF-AGGGGAALAGGCLRGR 67 R D + G+ + G ++RGG + H + R G++ A G A AG RGR Sbjct: 469 RGDKKQGRQKASAAGTKSRGG-----GLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGR 523 Query: 68 GAERGRRVREQGGDGRW---QRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVV 124 R ++ G R + RQR G HG GG + +R R G Sbjct: 524 KQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQ-WGQTA 582 Query: 125 ATRHGDGGG 133 A GGG Sbjct: 583 AAAKTRGGG 591 Score = 31.2 bits (69), Expect = 2.1 Identities = 33/113 (29%), Positives = 49/113 (43%), Gaps = 14/113 (12%) Query: 8 WGRQDWEP--GKASEVVGRRTRG--GVGSCGSVHRHRVQGGGRAGERFAGGGGA-ALAGG 62 W R+ +P GK+ G ++RG G S GS G A + GGGGA GG Sbjct: 711 WQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGG 770 Query: 63 CLRGRGAER-----GRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARR 110 + R E+ G++ GG + + RG G++ GG++ RR Sbjct: 771 GAKSRSGEKAVTAGGQKAAAAGGKKPPRVKSRGGRGQKA----AAGGKKPLRR 819 Score = 30.8 bits (68), Expect = 2.7 Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 2/110 (1%) Query: 24 RRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLR--GRGAERGRRVREQGGD 81 RR G+ R G + + GG G GG GRG ++ RR ++ Sbjct: 275 RRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATK 334 Query: 82 GRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDG 131 +RG GG++ G ++ RR ++ +R A A G G Sbjct: 335 AAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGG 384 Score = 30.0 bits (66), Expect = 4.6 Identities = 50/210 (23%), Positives = 74/210 (35%), Gaps = 25/210 (11%) Query: 25 RTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRRVR---EQGGD 81 ++R G G +HR G + GGG RG+ A G + R +GG Sbjct: 211 KSRFGKTRGGRRKKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGG 270 Query: 82 GRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGA 141 + RRQ GQ A A+R G A + G GG GG Sbjct: 271 DKKLRRQ---------------GQNAALAGAKRRGAATAGEKPAAK-GRGGRGPKSLGGQ 314 Query: 142 IHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLD---GEGVLEARG 198 W G ++ Q + +G + GG GQ +V + G+ + Sbjct: 315 NPRWGRGGKKPRRRGQKATKAAAAGTK-RGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKA 373 Query: 199 LRHAAQVVGGGGH--LWQVRARGRQRAEPQ 226 A+ GGG L + + RG R +P+ Sbjct: 374 SAAGAKSRGGGDKKGLREAKRRGDGRKKPR 403 Score = 29.6 bits (65), Expect = 6.0 Identities = 50/227 (22%), Positives = 81/227 (35%), Gaps = 58/227 (25%) Query: 1 MGGGEWGWGRQDWEPG----KASEVVGRRTRGGVGS--------CGSVHRHRVQGGGRAG 48 +GG WGR +P KA++ T+ G G S + R +G Sbjct: 311 LGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRR 370 Query: 49 ERFAGGGGAALAGGCLRG--------------------RGAERGRRVREQGGDGRWQRRQ 88 ++ + G + GG +G R A++ + +GG + RR Sbjct: 371 QKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRR- 429 Query: 89 RGHGGRRGLNGHG-DGGQRLARRVAQRLQRHAVGAVVATRHGD----------------G 131 RG + G GG + RR Q+ ++ A A +R GD G Sbjct: 430 RGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESR-GDKKQGRQKASAAGTKSRG 488 Query: 132 GGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPR 178 GG H+G ++W G + ++ GE+ + G QP R Sbjct: 489 GGLKSHSGK--NLWRRGQK-----AEAAGEKATAAGAKSRGRKQPRR 528 >gi|239749709 PREDICTED: hypothetical protein [Homo sapiens] Length = 178 Score = 40.8 bits (94), Expect = 0.003 Identities = 44/154 (28%), Positives = 54/154 (35%), Gaps = 16/154 (10%) Query: 16 GKASEVVGRRTRGGVGSCGSVHRHRVQG-------GGRAGERFAGGGGAALAGGCLRGRG 68 G+AS G R R G+G G R R +G G R GG A A G Sbjct: 2 GEASSAPGGRGRSGLGGSGGAPRVRGRGTAVGVGIGVRVWRSRRAEGGGAEAAAARTAGG 61 Query: 69 AERGRRVREQGGDGRWQRRQR-GHG----GRR----GLNGHGDGGQRLARRVAQRLQRHA 119 R +R D R +R HG G R G G G Q R+ ++ H Sbjct: 62 EPRAQRQAGSQADEEGGRPERVNHGQVPQGERLRAMAKGGVGKGSQGAERQASRPHAEHR 121 Query: 120 VGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAA 153 +G TR G AG A P G + A Sbjct: 122 LGLSHLTRAAGAGAARRRAGAARTRSPKGCRAGA 155 Score = 31.2 bits (69), Expect = 2.1 Identities = 38/141 (26%), Positives = 47/141 (33%), Gaps = 40/141 (28%) Query: 44 GGRAGERFAGGGGAALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDG 103 GGR G GGA +RGRG G + G W+ R+ GG G Sbjct: 9 GGRGRSGLGGSGGAPR----VRGRGTAVGVGI----GVRVWRSRRAEGGGAEAAAARTAG 60 Query: 104 GQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERV 163 G+ A+R A G + D GG +R HG GER+ Sbjct: 61 GEPRAQRQA-------------------GSQADEEGGR-------PERVNHGQVPQGERL 94 Query: 164 ------GSGHRLHGGEGQPPR 178 G G G E Q R Sbjct: 95 RAMAKGGVGKGSQGAERQASR 115 >gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo sapiens] Length = 351 Score = 40.4 bits (93), Expect = 0.003 Identities = 45/167 (26%), Positives = 71/167 (42%), Gaps = 24/167 (14%) Query: 26 TRGGVGSCGSVHRHRVQGGG-----RAGERFA---GGGGAALAGGCLRGRGAERGRRVRE 77 +R G C S ++R GGG R G++ A GGGG G G GA++ R+ R Sbjct: 124 SRAGSRVCRSRPQNR--GGGDKKPRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRR 181 Query: 78 QGGDGRWQRRQRGHGGRR-----GLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGG 132 +G R GG++ G GG++ A ++ +R G A G G Sbjct: 182 RG------ERAAAAGGKKLQKAAAAKSRGGGGKKTAAAGGKKPRRRR-GQKAAKSRGGGD 234 Query: 133 GRVDHAGGAI-HVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPR 178 +++ A+ V G ++ G + ER G + GG G+ P+ Sbjct: 235 KKLERQKAALTGVKSRGDKKPLRGGKKQRER-GQNTKSRGGGGEKPQ 280 >gi|31542255 hypothetical protein LOC140706 [Homo sapiens] Length = 433 Score = 40.4 bits (93), Expect = 0.003 Identities = 39/108 (36%), Positives = 43/108 (39%), Gaps = 9/108 (8%) Query: 7 GWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRG 66 G GR PG A E T + S+ GGG A R GGGG +L R Sbjct: 172 GAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLE----RQ 227 Query: 67 RGAER--GRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVA 112 R R G R Q G W+RR HGG G G G G RR A Sbjct: 228 RAGARASGSWERRQTFSGSWERR---HGGGGGGGGAGKPGGSWERRQA 272 Score = 39.7 bits (91), Expect = 0.006 Identities = 29/85 (34%), Positives = 34/85 (40%), Gaps = 5/85 (5%) Query: 6 WGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLR 65 WG G + G R R G + GS R + G + ER GGGG GG Sbjct: 207 WGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSG--SWERRHGGGG---GGGGAG 261 Query: 66 GRGAERGRRVREQGGDGRWQRRQRG 90 G RR GG G W+RR G Sbjct: 262 KPGGSWERRQAGSGGGGSWERRHPG 286 Score = 35.0 bits (79), Expect = 0.14 Identities = 40/139 (28%), Positives = 53/139 (38%), Gaps = 21/139 (15%) Query: 93 GRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDH-----AGGAIHVWPA 147 G G + GG RRV +RH + ++ R G GGG + GG++ A Sbjct: 171 GGAGRDPGPPGGAPEKRRVGTAERRHTICSL-DWRMGWGGGAAEARAGGGGGGSLERQRA 229 Query: 148 GAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVG 207 GA RA+ + GS R HGG G G G + G Q Sbjct: 230 GA-RASGSWERRQTFSGSWERRHGGGG--------------GGGGAGKPGGSWERRQAGS 274 Query: 208 GGGHLWQVRARGRQRAEPQ 226 GGG W+ R G +PQ Sbjct: 275 GGGGSWERRHPGPNPLDPQ 293 >gi|62122917 filaggrin family member 2 [Homo sapiens] Length = 2391 Score = 40.0 bits (92), Expect = 0.004 Identities = 56/199 (28%), Positives = 68/199 (34%), Gaps = 44/199 (22%) Query: 19 SEVVGRRTRG------GVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERG 72 S GRR G G G H H G+AG + E G Sbjct: 1945 SRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYP-----------------ESG 1987 Query: 73 RRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGG 132 V E+ G Q R G +GHG QR +R +R H + + G G Sbjct: 1988 SSVHERHGTTHGQTADTT---RHGHSGHGQSTQRGSRTTGRRASGH---SEYSDSEGHSG 2041 Query: 133 GRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLDGEG 192 H+G A AG+Q GS V ER G+ HG G RH G G Sbjct: 2042 VSHTHSGHA--HGQAGSQHGESGSS-VHERHGT---THGQTGDTTRH-------AHSGHG 2088 Query: 193 VLEARGLRHAAQVVGGGGH 211 RG R A + G GH Sbjct: 2089 QSTQRGSRTAGR--RGSGH 2105 Score = 32.3 bits (72), Expect = 0.93 Identities = 48/205 (23%), Positives = 66/205 (32%), Gaps = 47/205 (22%) Query: 9 GRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRA---GERFAGGGGAA------- 58 G+ + G++ V R G G RH G G++ G R AG G+ Sbjct: 2052 GQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDS 2111 Query: 59 -LAGGCLRGRGAERGRRVREQGGD------GRWQ--RRQRGHGGRRGLNGHGDGGQRLAR 109 + G + R Q G+ GR Q G R G +GHG Q +R Sbjct: 2112 EVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSR 2171 Query: 110 RVAQRLQRHA------------------VGAVVATRHGDGGGRVDHAGGAIHVWPAGAQR 151 ++ H+ + +RHG G G H R Sbjct: 2172 TTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTR 2231 Query: 152 AAH---------GSQLVGERVGSGH 167 AH GS+ G R GSGH Sbjct: 2232 HAHYGYGQSTQRGSRTTGRR-GSGH 2255 Score = 29.3 bits (64), Expect = 7.9 Identities = 31/105 (29%), Positives = 35/105 (33%), Gaps = 7/105 (6%) Query: 67 RGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARR---VAQRLQRHAVG-A 122 R A G Q G RR GH GH QR R Q +H + Sbjct: 1779 RHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESES 1838 Query: 123 VVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSGH 167 +V RHG G+ G H Q GS G R SGH Sbjct: 1839 IVDERHGTTHGQTGDTSG--HSQSGHGQSTQSGSSTTGRR-RSGH 1880 >gi|55956899 keratin 9 [Homo sapiens] Length = 623 Score = 40.0 bits (92), Expect = 0.004 Identities = 51/179 (28%), Positives = 62/179 (34%), Gaps = 33/179 (18%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSC----GSVHRHRVQGGGRAGERFAGGGGA 57 G G+ G G + G GR +RGG G GS + G R G + GGG+ Sbjct: 469 GAGKIGLGGRGGSGGS----YGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGS 524 Query: 58 ALAGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVAQRLQR 117 GG G G G G G +GG G G GG Sbjct: 525 GSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGG------------- 571 Query: 118 HAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERV-GSGHRLHGGEGQ 175 G +R G GG H GG +G + GS GE GSG GG G+ Sbjct: 572 --YGGGSGSRGGSGG---SHGGG------SGFGGESGGSYGGGEEASGSGGGYGGGSGK 619 Score = 35.4 bits (80), Expect = 0.11 Identities = 30/85 (35%), Positives = 34/85 (40%), Gaps = 8/85 (9%) Query: 28 GGVGSCGSVH----RHRVQGGGRAGERF--AGGGGAALAGGCLRGRGAERGRRVREQGGD 81 GG+GS GS+ R GGG G RF + G G + C RG G G G Sbjct: 20 GGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGG 79 Query: 82 GRWQRRQRG--HGGRRGLNGHGDGG 104 G G GG RG G GG Sbjct: 80 GFSASSLGGGFGGGSRGFGGASGGG 104 Score = 34.3 bits (77), Expect = 0.25 Identities = 35/103 (33%), Positives = 39/103 (37%), Gaps = 18/103 (17%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAG 61 GGG + G +S V GR GG GS G + GGG G A G G Sbjct: 41 GGGGGRFSSSSGYGGGSSRVCGR---GGGGSFGYSY-----GGGSGGGFSASSLGGGFGG 92 Query: 62 GCLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGG 104 G RG G G GG G GG G +G G GG Sbjct: 93 GS-RGFGGASGGGYSSSGGFG---------GGFGGGSGGGFGG 125 Score = 30.4 bits (67), Expect = 3.5 Identities = 25/82 (30%), Positives = 28/82 (34%), Gaps = 1/82 (1%) Query: 2 GGGEWGWGRQDWEPGKAS-EVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALA 60 GGG +G+ G S +G GG G G G F GG G Sbjct: 65 GGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFG 124 Query: 61 GGCLRGRGAERGRRVREQGGDG 82 GG G G G GGDG Sbjct: 125 GGYGSGFGGFGGFGGGAGGGDG 146 Score = 30.4 bits (67), Expect = 3.5 Identities = 31/98 (31%), Positives = 34/98 (34%), Gaps = 10/98 (10%) Query: 3 GGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGG 62 GG G G G S G GG GS G GG G GG G + GG Sbjct: 535 GGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSG-----GGYGGGSGSRGGSGGSHGGG 589 Query: 63 CLRGRGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGH 100 G G E G GG G+GG G + H Sbjct: 590 S--GFGGESGG---SYGGGEEASGSGGGYGGGSGKSSH 622 >gi|239758151 PREDICTED: hypothetical protein XP_002346314 [Homo sapiens] Length = 321 Score = 39.7 bits (91), Expect = 0.006 Identities = 50/180 (27%), Positives = 67/180 (37%), Gaps = 31/180 (17%) Query: 7 GWGRQDWEPGKASEVVGRRTRGGVGSCGSVH-RHRVQGGGRAGERFAGGGG-----AALA 60 G G++ KA+ + GGV S G R R Q AG + GGGG A Sbjct: 147 GGGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGKKPQKARAV 206 Query: 61 GGCLRG--------------RGAERGRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQR 106 G RG G + G+++R+QG GR + R RRG GG+R Sbjct: 207 GARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQGEKGRKKPR------RRGQKAAAAGGER 260 Query: 107 LARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRAAHGSQLVGERVGSG 166 ++ +R AV A RV ++ QR S RVGSG Sbjct: 261 -----CKKPRRQKAAAVSAKSPKKPRRRVLNSARLGAESRKNPQRRGQKSMAAKSRVGSG 315 Score = 33.5 bits (75), Expect = 0.42 Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%) Query: 25 RTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERGRR-VREQGGDGR 83 +TRGG G R Q AG + GGG + G +R RG + + GG G+ Sbjct: 143 QTRGG----GGKKPRRGQKAATAGAKSRGGGVRSRGGKKIRRRGQKAAAAGAKSCGGGGK 198 Query: 84 WQRRQRGHGG---------RRGLNGHGDGGQRLARRVAQR 114 ++ R G RRG GG++ +++ Q+ Sbjct: 199 KPQKARAVGARRRGWKKLRRRGKKAAAAGGEKAGKKLRQQ 238 >gi|239750393 PREDICTED: hypothetical protein [Homo sapiens] Length = 373 Score = 39.7 bits (91), Expect = 0.006 Identities = 59/194 (30%), Positives = 70/194 (36%), Gaps = 26/194 (13%) Query: 43 GGGRAGER------FAGGGGAAL--AGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGR 94 GGGR R F GG L G LRG G RG +R Q R + R G G Sbjct: 112 GGGRHSPRPAVGTIFRGGRKGRLREGRGALRGSGKRRGWGLRPQ----RVRSRLAGLGAP 167 Query: 95 RG--LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRA 152 RG G GGQ A+RL H G GGG + GG P A++ Sbjct: 168 RGGAAAPRGWGGQG-----AERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQP 222 Query: 153 AHGSQLVGER--VGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGG 210 G +GS R H G RH R V + R AA V Sbjct: 223 PSGRPRPRRTRLLGSAER-HTGRAALARHGQLSRPHA----AVRNSSRGRGAATSVSAAA 277 Query: 211 HLWQVRARGRQRAE 224 + ARG +RA+ Sbjct: 278 RPTRGGARGHRRAD 291 >gi|239744694 PREDICTED: hypothetical protein [Homo sapiens] Length = 373 Score = 39.7 bits (91), Expect = 0.006 Identities = 59/194 (30%), Positives = 70/194 (36%), Gaps = 26/194 (13%) Query: 43 GGGRAGER------FAGGGGAAL--AGGCLRGRGAERGRRVREQGGDGRWQRRQRGHGGR 94 GGGR R F GG L G LRG G RG +R Q R + R G G Sbjct: 112 GGGRHSPRPAVGTIFRGGRKGRLREGRGALRGSGKRRGWGLRPQ----RVRSRLAGLGAP 167 Query: 95 RG--LNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDHAGGAIHVWPAGAQRA 152 RG G GGQ A+RL H G GGG + GG P A++ Sbjct: 168 RGGAAAPRGWGGQG-----AERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQP 222 Query: 153 AHGSQLVGER--VGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVGGGG 210 G +GS R H G RH R V + R AA V Sbjct: 223 PSGRPRPRRTRLLGSAER-HTGRAALARHGQLSRPHA----AVRNSSRGRGAATSVSAAA 277 Query: 211 HLWQVRARGRQRAE 224 + ARG +RA+ Sbjct: 278 RPTRGGARGHRRAD 291 >gi|9966841 cell death regulator aven [Homo sapiens] Length = 362 Score = 39.7 bits (91), Expect = 0.006 Identities = 31/75 (41%), Positives = 33/75 (44%), Gaps = 5/75 (6%) Query: 23 GRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRGRGAERG----RRVREQ 78 GR R G G G RH + G A GGGG GG RGRG RG R R Sbjct: 10 GRGRRPGRGRPGG-DRHSERPGAAAAVARGGGGGGGGDGGGRRGRGRGRGFRGARGGRGG 68 Query: 79 GGDGRWQRRQRGHGG 93 GG R RR+ G G Sbjct: 69 GGAPRGSRREPGGWG 83 Score = 31.6 bits (70), Expect = 1.6 Identities = 32/82 (39%), Positives = 34/82 (41%), Gaps = 15/82 (18%) Query: 2 GGGEWGWGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERF-AGGGGAALA 60 G G G R PG A+ V R GG G G R R +G G G R GGG Sbjct: 16 GRGRPGGDRHSERPGAAA-AVARGGGGGGGGDGGGRRGRGRGRGFRGARGGRGGG----- 69 Query: 61 GGCLRGRGAERGRRVREQGGDG 82 GA RG R RE GG G Sbjct: 70 -------GAPRGSR-REPGGWG 83 >gi|28875797 small protein rich in arginine and glycine [Homo sapiens] Length = 248 Score = 39.3 bits (90), Expect = 0.008 Identities = 35/100 (35%), Positives = 43/100 (43%), Gaps = 17/100 (17%) Query: 22 VGRRTRGGVGSCGS--VHRHRVQGG---GRAGERFAGGGGAALAGGCLRG---------- 66 +G RG +G G + R +GG GRA GG + LRG Sbjct: 92 IGALARGAIGGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGL 151 Query: 67 -RGAERGRRVREQGGDGRWQRRQRGHGGR-RGLNGHGDGG 104 RG RGR +GG GR + G GGR RG+ G G GG Sbjct: 152 RRGGVRGRGGPGRGGLGRGAMGRGGIGGRGRGMIGRGRGG 191 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.140 0.446 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,614,476 Number of Sequences: 37866 Number of extensions: 1210833 Number of successful extensions: 6889 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 50 Number of HSP's successfully gapped in prelim test: 248 Number of HSP's that attempted gapping in prelim test: 5508 Number of HSP's gapped (non-prelim): 1053 length of query: 463 length of database: 18,247,518 effective HSP length: 106 effective length of query: 357 effective length of database: 14,233,722 effective search space: 5081438754 effective search space used: 5081438754 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.