Guide to the Human Genome
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Name: HSD11B2 Sequence: fasta or formatted (405aa) NCBI GI: 119392083
Description:

hydroxysteroid (11-beta) dehydrogenase 2

Referenced in:

Alcohol and Aldehyde Dehydrogenases
Kidney
Steroid Hormones

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.4         46           3
 C cysteine            2.2          9           2
 D aspartate           3.7         15           1
 E glutamate           3.7         15           1
 F phenylalanine       3.2         13           2
 G glycine             7.9         32           2
 H histidine           1.7          7           1
 I isoleucine          2.7         11           2
 K lysine              3.0         12           2
 L leucine            16.8         68           3
 M methionine          2.0          8           1
 N asparagine          2.0          8           2
 P proline             7.9         32           3
 Q glutamine           4.0         16           1
 R arginine            7.4         30           3
 S serine              5.7         23           2
 T threonine           5.2         21           2
 V valine              5.4         22           2
 W tryptophan          2.0          8           1
 Y tyrosine            2.2          9           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hydroxysteroid (11-beta) dehydrogenase 2 
HSD17B2               0.273   hydroxysteroid (17-beta) dehydrogenase 2 
BDH1                  0.173   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
BDH1                  0.173   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
BDH1                  0.173   3-hydroxybutyrate dehydrogenase, type 1 precursor [H...
HSD17B6               0.165   hydroxysteroid (17-beta) dehydrogenase 6 
RDH5                  0.164   retinol dehydrogenase 5 (11-cis and 9-cis) 
DHRS9                 0.162   NADP-dependent retinol dehydrogenase/reductase [Homo...
DHRS9                 0.162   NADP-dependent retinol dehydrogenase/reductase [Hom...
DHRS9                 0.162   NADP-dependent retinol dehydrogenase/reductase [Hom...
DHRS9                 0.162   NADP-dependent retinol dehydrogenase/reductase [Homo...
RDH16                 0.159   retinol dehydrogenase 16 
SDR9C7                0.144   short chain dehydrogenase/reductase family 9C, membe...
HSD17B1               0.066   hydroxysteroid (17-beta) dehydrogenase 1 
DHRS7B                0.063   dehydrogenase/reductase (SDR family) member 7B [Homo...
RDH8                  0.063   retinol dehydrogenase 8 (all-trans) 
HSD17B14              0.054   dehydrogenase/reductase (SDR family) member 10 [Homo...
DHRS7                 0.053   dehydrogenase/reductase (SDR family) member 7 
DHRS2                 0.044   dehydrogenase/reductase member 2 isoform 2 
HSD11B1               0.044   11-beta-hydroxysteroid dehydrogenase 1 
HSD11B1               0.044   11-beta-hydroxysteroid dehydrogenase 1 
DHRS2                 0.044   dehydrogenase/reductase member 2 isoform 1 
KDSR                  0.043   3-ketodihydrosphingosine reductase precursor 
HSD17B11              0.042   estradiol 17-beta-dehydrogenase 11 
DHRS7C                0.040   dehydrogenase/reductase (SDR family) member 7C [Hom...
DHRS4                 0.038   peroxisomal short-chain alcohol dehydrogenase 
RDH13                 0.034   retinol dehydrogenase 13 isoform 1 
RDH12                 0.033   retinol dehydrogenase 12 
HSD17B13              0.033   hydroxysteroid (17-beta) dehydrogenase 13 isoform A...
HSD11B1L              0.032   short-chain dehydrogenase/reductase 10 isoform e [Ho...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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