BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239752630 PREDICTED: hypothetical protein XP_002347769 [Homo sapiens] (127 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239752630 PREDICTED: hypothetical protein XP_002347769 [Homo ... 266 3e-72 gi|110431370 espin [Homo sapiens] 159 4e-40 gi|155969701 espin-like [Homo sapiens] 96 7e-21 gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 53 7e-08 gi|70995267 ankyrin repeat domain 29 [Homo sapiens] 52 2e-07 gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 51 3e-07 gi|24308163 fem-1 homolog a [Homo sapiens] 50 4e-07 gi|41327754 ankyrin repeat domain 3 [Homo sapiens] 50 5e-07 gi|8051593 GA binding protein transcription factor, beta subunit... 50 5e-07 gi|8051595 GA binding protein transcription factor, beta subunit... 50 5e-07 gi|32483404 GA binding protein transcription factor, beta subuni... 50 5e-07 gi|8051597 GA binding protein transcription factor, beta subunit... 50 5e-07 gi|8051599 GA binding protein transcription factor, beta subunit... 50 5e-07 gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 49 8e-07 gi|223634006 hypothetical protein LOC441869 [Homo sapiens] 48 2e-06 gi|24233530 ankyrin repeat domain 44 [Homo sapiens] 48 2e-06 gi|17864094 feminization 1 homolog a [Homo sapiens] 47 3e-06 gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 47 5e-06 gi|116534990 ankyrin-like protein 1 [Homo sapiens] 46 7e-06 gi|41327752 diabetes related ankyrin repeat protein [Homo sapiens] 46 7e-06 gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens] 46 9e-06 gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens] 46 9e-06 gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens] 46 9e-06 gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens] 46 9e-06 gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens] 46 9e-06 gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 45 1e-05 gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 45 1e-05 gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 45 1e-05 gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 45 1e-05 gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 45 1e-05 >gi|239752630 PREDICTED: hypothetical protein XP_002347769 [Homo sapiens] Length = 127 Score = 266 bits (680), Expect = 3e-72 Identities = 127/127 (100%), Positives = 127/127 (100%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI Sbjct: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 Query: 61 SADLWGGTALYDAAENGELEVSAGPGWGRAPSAGTALSARPCPGAGVPARGRGRVLTACP 120 SADLWGGTALYDAAENGELEVSAGPGWGRAPSAGTALSARPCPGAGVPARGRGRVLTACP Sbjct: 61 SADLWGGTALYDAAENGELEVSAGPGWGRAPSAGTALSARPCPGAGVPARGRGRVLTACP 120 Query: 121 HSAARSW 127 HSAARSW Sbjct: 121 HSAARSW 127 >gi|110431370 espin [Homo sapiens] Length = 854 Score = 159 bits (403), Expect = 4e-40 Identities = 76/80 (95%), Positives = 78/80 (97%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATA HFAASRGH+KVLSWLLLHGGEI Sbjct: 207 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEI 266 Query: 61 SADLWGGTALYDAAENGELE 80 SADLWGGT L+DAAENGELE Sbjct: 267 SADLWGGTPLHDAAENGELE 286 Score = 57.8 bits (138), Expect = 2e-09 Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 2/79 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGG--E 59 TP H A+ GH + WL+S + ++D GAT H AA GH +V++WLL HGG Sbjct: 72 TPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDP 131 Query: 60 ISADLWGGTALYDAAENGE 78 +A G ++ AA G+ Sbjct: 132 TAATDMGALPIHYAAAKGD 150 Score = 47.0 bits (110), Expect = 4e-06 Identities = 36/106 (33%), Positives = 50/106 (47%), Gaps = 10/106 (9%) Query: 3 PLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGG--EI 60 P+H AA+ G + +LV + + + ++GAT H A++ GH L WLL GG Sbjct: 39 PVHHAARAGKLHCLRFLVEEAALPAAARARNGATPAHDASATGHLACLQWLLSQGGCRVQ 98 Query: 61 SADLWGGTALYDAAENGELEVSAGPGW-----GRAPSAGTALSARP 101 D G T L+ AA G EV W G P+A T + A P Sbjct: 99 DKDNSGATVLHLAARFGHPEV---VNWLLHHGGGDPTAATDMGALP 141 Score = 37.0 bits (84), Expect = 0.004 Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query: 3 PLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLH-GGEIS 61 P+H AA G P + LV ++ Q K+GAT + A GH +V +L+ G + Sbjct: 141 PIHYAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPH 200 Query: 62 ADLWGG-TALYDAAENGELEV 81 A G T L+ AA+ G V Sbjct: 201 ARAHDGMTPLHAAAQMGHSPV 221 Score = 30.0 bits (66), Expect = 0.50 Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 1/52 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWL 53 TPLH AA+ G LV L +D+DG TA + GHS +L Sbjct: 274 TPLHDAAENGELECCQILV-VNGAELDVRDRDGYTAADLSDFNGHSHCTRYL 324 >gi|155969701 espin-like [Homo sapiens] Length = 1005 Score = 95.9 bits (237), Expect = 7e-21 Identities = 45/80 (56%), Positives = 58/80 (72%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 M+ LHAAA GH ++VWLV+ TD+ L+ +D +GATA HFAA GH+ +L LLL G I Sbjct: 206 MSALHAAAARGHYSLVVWLVTFTDIGLTARDNEGATALHFAARGGHTPILDRLLLMGTPI 265 Query: 61 SADLWGGTALYDAAENGELE 80 D WGGT L+DAAENG++E Sbjct: 266 LRDSWGGTPLHDAAENGQME 285 Score = 48.1 bits (113), Expect = 2e-06 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 1/79 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TP H AA G + WLV L +QD G + H AA GH ++ WLL G + Sbjct: 72 TPAHDAAATGSLAELCWLVREGGCGLQDQDASGVSPLHLAARFGHPVLVEWLLHEGHSAT 131 Query: 62 ADL-WGGTALYDAAENGEL 79 + G L+ AA +G+L Sbjct: 132 LETREGARPLHHAAVSGDL 150 Score = 38.9 bits (89), Expect = 0.001 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 3/84 (3%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWL-LLHGGE 59 ++PLH AA+ GH ++ WL+ S + + ++GA H AA G L L HG Sbjct: 105 VSPLHLAARFGHPVLVEWLLH-EGHSATLETREGARPLHHAAVSGDLTCLKLLTAAHGSS 163 Query: 60 ISADLWGGTA-LYDAAENGELEVS 82 ++ G + LY A + G L ++ Sbjct: 164 VNRRTRSGASPLYLACQEGHLHLA 187 Score = 36.2 bits (82), Expect = 0.007 Identities = 18/55 (32%), Positives = 29/55 (52%) Query: 4 LHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGG 58 +H A + GH + +LV + +++ +GAT H AA+ G L WL+ GG Sbjct: 40 VHHATRAGHLDCVKFLVQRAQLPGNQRAHNGATPAHDAAATGSLAELCWLVREGG 94 Score = 31.6 bits (70), Expect = 0.17 Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 1/52 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWL 53 TPLH AA+ G LVS V S +D+DG TA A GH +L Sbjct: 273 TPLHDAAENGQMECCQTLVS-HHVDPSLRDEDGYTAADLAEYHGHRDCAQYL 323 >gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 [Homo sapiens] Length = 1166 Score = 52.8 bits (125), Expect = 7e-08 Identities = 30/81 (37%), Positives = 47/81 (58%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH AA G V+ +L+ ++ +D G H A S GH++V++ LL HG + + Sbjct: 60 TPLHFAAGFGRKDVVEYLLQ-NGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPN 118 Query: 62 A-DLWGGTALYDAAENGELEV 81 A D W T L++AA G+++V Sbjct: 119 ARDNWNYTPLHEAAIKGKIDV 139 Score = 50.4 bits (119), Expect = 4e-07 Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH AA V+ +L+ + +DK G H A S GH +V L+ HG ++ Sbjct: 528 TPLHFAAGYNRVSVVEYLLQ-HGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVN 586 Query: 62 -ADLWGGTALYDAAENGELEV 81 ADLW T L++AA G+ E+ Sbjct: 587 VADLWKFTPLHEAAAKGKYEI 607 Score = 46.2 bits (108), Expect = 7e-06 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 2/83 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH AA + V +L+ ++ QDK G H AAS GH V + L+ + ++ Sbjct: 681 TPLHLAAGYNNLEVAEYLLQ-HGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVN 739 Query: 62 A-DLWGGTALYDAAENGELEVSA 83 A D W T L++AA+ G ++ A Sbjct: 740 ATDKWAFTPLHEAAQKGRTQLCA 762 Score = 45.4 bits (106), Expect = 1e-05 Identities = 32/82 (39%), Positives = 44/82 (53%), Gaps = 4/82 (4%) Query: 2 TPLHAAAQMGHSPV-IVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 TPLH AA G++ V IV L+ + +DK H A S GH +V L+ HG + Sbjct: 213 TPLHLAA--GYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACV 270 Query: 61 SA-DLWGGTALYDAAENGELEV 81 +A DLW T L++AA +EV Sbjct: 271 NAMDLWQFTPLHEAASKNRVEV 292 Score = 38.5 bits (88), Expect = 0.001 Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 2/100 (2%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 +TPLH A++ H+ V+ +V + ++ D G T+ H AA GH + LL +G + Sbjct: 401 LTPLHVASEKAHNDVVEVVVK-HEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDP 459 Query: 61 S-ADLWGGTALYDAAENGELEVSAGPGWGRAPSAGTALSA 99 + L G TAL EN + + G G + + L A Sbjct: 460 NIISLQGFTALQMGNENVQQLLQEGISLGNSEADRQLLEA 499 Score = 36.6 bits (83), Expect = 0.005 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGE 59 + PLH AA GH V L+ + ++ DK T H AA +G +++ + LL HG + Sbjct: 713 LIPLHNAASYGHVDVAALLIK-YNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGAD 770 Score = 36.2 bits (82), Expect = 0.007 Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Query: 22 CTDVSLSEQDKDGATAT--HFAASRGHSKVLSWLLLHGGEISA-DLWGGTALYDAAENGE 78 CT S++ +D +G +T HFAA V+ +LL HG ++ A D G L++A G Sbjct: 512 CTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGH 571 Query: 79 LEVS 82 EV+ Sbjct: 572 YEVA 575 Score = 35.0 bits (79), Expect = 0.016 Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 1/78 (1%) Query: 7 AAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISADLWG 66 AA+ G + L S +V+ + +T H AA + +V +LL HG +++A G Sbjct: 652 AAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKG 711 Query: 67 G-TALYDAAENGELEVSA 83 G L++AA G ++V+A Sbjct: 712 GLIPLHNAASYGHVDVAA 729 Score = 32.3 bits (72), Expect = 0.10 Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Query: 7 AAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLW 65 +A+ G+ ++ L++ +V+ D +T H AA K++ LL HG ++ A D Sbjct: 184 SARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKG 243 Query: 66 GGTALYDAAENGELEVS 82 L++A G EV+ Sbjct: 244 DLVPLHNACSYGHYEVT 260 Score = 32.0 bits (71), Expect = 0.13 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 1/84 (1%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 + PLH A GH+ V+ L+ + +D T H AA +G V LL HG E Sbjct: 92 LIPLHNACSFGHAEVVNLLLR-HGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEP 150 Query: 61 SADLWGGTALYDAAENGELEVSAG 84 + G D A+ V G Sbjct: 151 TIRNTDGRTALDLADPSAKAVLTG 174 Score = 30.0 bits (66), Expect = 0.50 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 3/62 (4%) Query: 23 TDVSLSEQDKDGATAT--HFAASRGHSKVLSWLLLHGGEISA-DLWGGTALYDAAENGEL 79 T ++ +D G +T HFAA G V+ +LL +G + A D G L++A G Sbjct: 45 TPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHA 104 Query: 80 EV 81 EV Sbjct: 105 EV 106 >gi|70995267 ankyrin repeat domain 29 [Homo sapiens] Length = 301 Score = 51.6 bits (122), Expect = 2e-07 Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T L AAQ GH+ V+ +L S + KDG TA A+ GH +V+ LL HG I Sbjct: 81 TALFFAAQQGHNDVVRFLFGF-GASTEFRTKDGGTALLAASQYGHMQVVETLLKHGANIH 139 Query: 62 ADLW-GGTALYDAAENGELEV 81 L+ G TAL+ AA+ G L+V Sbjct: 140 DQLYDGATALFLAAQGGYLDV 160 Score = 42.0 bits (97), Expect = 1e-04 Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T L AA+Q GH V+ L+ ++ +Q DGATA AA G+ V+ LL G +++ Sbjct: 114 TALLAASQYGHMQVVETLLK-HGANIHDQLYDGATALFLAAQGGYLDVIRLLLASGAKVN 172 Query: 62 ADLWGGTA-LYDAAENGELEV 81 GTA L+ A++ G EV Sbjct: 173 QPRQDGTAPLWIASQMGHSEV 193 Score = 36.2 bits (82), Expect = 0.007 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T L AAQ G+ VI L++ + +++ +DG A+ GHS+V+ +LL G + Sbjct: 147 TALFLAAQGGYLDVIRLLLA-SGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRGADRD 205 Query: 62 ADLWGG-TALYDAAENGELEV 81 A G TAL AA G +V Sbjct: 206 AARNDGTTALLKAANKGYNDV 226 Score = 35.4 bits (80), Expect = 0.012 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 7/100 (7%) Query: 7 AAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISADLWG 66 AA+ G+ ++ L++ V + +D G T AA GH + L+L G +I+ Sbjct: 19 AARRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADINLQRES 78 Query: 67 G-TALYDAAENGELEVSAGP-GWG-----RAPSAGTALSA 99 G TAL+ AA+ G +V G+G R GTAL A Sbjct: 79 GTTALFFAAQQGHNDVVRFLFGFGASTEFRTKDGGTALLA 118 >gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase [Homo sapiens] Length = 1327 Score = 50.8 bits (120), Expect = 3e-07 Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH AA V+ +L+ + +DK G H A S GH +V L+ HG ++ Sbjct: 686 TPLHFAAGYNRVSVVEYLLH-HGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744 Query: 62 -ADLWGGTALYDAAENGELEV 81 ADLW T L++AA G+ E+ Sbjct: 745 VADLWKFTPLHEAAAKGKYEI 765 Score = 49.3 bits (116), Expect = 8e-07 Identities = 34/82 (41%), Positives = 45/82 (54%), Gaps = 4/82 (4%) Query: 2 TPLHAAAQMGHSPV-IVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 TPLH AA G++ V IV L+ + +DK G H A S GH +V LL HG + Sbjct: 371 TPLHLAA--GYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACV 428 Query: 61 SA-DLWGGTALYDAAENGELEV 81 +A DLW T L++AA +EV Sbjct: 429 NAMDLWQFTPLHEAASKNRVEV 450 Score = 45.1 bits (105), Expect = 2e-05 Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 2/83 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH AA + V +L+ ++ QDK G H AAS GH + + L+ + ++ Sbjct: 839 TPLHLAAGYNNLEVAEYLLE-HGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVN 897 Query: 62 A-DLWGGTALYDAAENGELEVSA 83 A D W T L++AA+ G ++ A Sbjct: 898 ATDKWAFTPLHEAAQKGRTQLCA 920 Score = 42.0 bits (97), Expect = 1e-04 Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 3/82 (3%) Query: 2 TPLHAAAQMGHSP--VIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGE 59 T LH A H + L+ +++E++KD T H AA R H+ V+ L HG + Sbjct: 524 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK 583 Query: 60 ISA-DLWGGTALYDAAENGELE 80 ++A D G TAL+ AA G L+ Sbjct: 584 MNALDTLGQTALHRAALAGHLQ 605 Score = 37.0 bits (84), Expect = 0.004 Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 3/65 (4%) Query: 22 CTDVSLSEQDKDGATAT--HFAASRGHSKVLSWLLLHGGEISADLWGG-TALYDAAENGE 78 CT +++ +D G +T H AA + +V +LL HG +++A GG L++AA G Sbjct: 823 CTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGH 882 Query: 79 LEVSA 83 ++++A Sbjct: 883 VDIAA 887 Score = 36.6 bits (83), Expect = 0.005 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 2/70 (2%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 MTPLH AA+ H+ V+ ++ ++ D G TA H AA GH + LL +G + Sbjct: 559 MTPLHVAAERAHNDVME-VLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDP 617 Query: 61 S-ADLWGGTA 69 S L G TA Sbjct: 618 SIISLQGFTA 627 Score = 36.2 bits (82), Expect = 0.007 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 1/77 (1%) Query: 7 AAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLW 65 A++ G + L S +V+ + + +T HFAA V+ +LL HG ++ A D Sbjct: 657 ASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKG 716 Query: 66 GGTALYDAAENGELEVS 82 G L++A G EV+ Sbjct: 717 GLVPLHNACSYGHYEVA 733 Score = 36.2 bits (82), Expect = 0.007 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGE 59 + PLH AA GH + L+ + ++ DK T H AA +G +++ + LL HG + Sbjct: 871 LIPLHNAASYGHVDIAALLIK-YNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGAD 928 Score = 35.8 bits (81), Expect = 0.009 Identities = 26/84 (30%), Positives = 36/84 (42%), Gaps = 1/84 (1%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 + PLH A GH+ V V L+ C + +D T H AA +G V LL HG + Sbjct: 250 LIPLHNACSFGHAEV-VSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP 308 Query: 61 SADLWGGTALYDAAENGELEVSAG 84 + G + D A+ V G Sbjct: 309 NIRNTDGKSALDLADPSAKAVLTG 332 Score = 35.4 bits (80), Expect = 0.012 Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Query: 7 AAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLW 65 AA+ G+ ++ L++ +V+ D +T H AA +++ LL HG ++ A D Sbjct: 342 AARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKG 401 Query: 66 GGTALYDAAENGELEVS 82 G L++A G EV+ Sbjct: 402 GLVPLHNACSYGHYEVT 418 Score = 32.3 bits (72), Expect = 0.10 Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 + PLH A GH V L+ ++ D T H AAS+ +V S LL HG + Sbjct: 403 LVPLHNACSYGHYEVTELLLK-HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP 461 Query: 61 SADLWGGTALYDAAENGEL 79 + G + D A EL Sbjct: 462 TLVNCHGKSAVDMAPTPEL 480 Score = 27.7 bits (60), Expect = 2.5 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 1/64 (1%) Query: 19 LVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLWGGTALYDAAENG 77 LV +V+ + ++ HFAA G V+ LL G + A D G L++A G Sbjct: 201 LVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFG 260 Query: 78 ELEV 81 EV Sbjct: 261 HAEV 264 >gi|24308163 fem-1 homolog a [Homo sapiens] Length = 669 Score = 50.4 bits (119), Expect = 4e-07 Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 1/81 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPL AA GH V+ +LV L ++ G T + +GH ++ +LL G +++ Sbjct: 118 TPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQVN 177 Query: 62 -ADLWGGTALYDAAENGELEV 81 G TAL+D AE+G LE+ Sbjct: 178 RRSAKGNTALHDCAESGSLEI 198 Score = 31.6 bits (70), Expect = 0.17 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 9/89 (10%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSE--------QDKDGATATHFAASRGHSKVLSWL 53 TPL AA+ GH V+ +LV S+ + +GA A++ GH V+ L Sbjct: 43 TPLLIAARYGHLDVVEYLVDRCGASVEAGGSVHFDGETIEGAPPLWAASAAGHLDVVRSL 102 Query: 54 LLHGGEIS-ADLWGGTALYDAAENGELEV 81 L G ++ T L A +G LEV Sbjct: 103 LRRGASVNRTTRTNSTPLRAACFDGHLEV 131 >gi|41327754 ankyrin repeat domain 3 [Homo sapiens] Length = 784 Score = 50.1 bits (118), Expect = 5e-07 Identities = 30/76 (39%), Positives = 40/76 (52%), Gaps = 1/76 (1%) Query: 3 PLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS- 61 PLH AA GH P++ L VS++ Q DG T H AA RGH +V L+ +++ Sbjct: 573 PLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNV 632 Query: 62 ADLWGGTALYDAAENG 77 L T L+ AAE G Sbjct: 633 CSLLAQTPLHVAAETG 648 Score = 43.5 bits (101), Expect = 4e-05 Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 2/60 (3%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T LH AA GHS V+ LVS + L D+ G +A H AA H++ + LL HG I+ Sbjct: 705 TALHLAAAHGHSEVVEELVSADVIDLF--DEQGLSALHLAAQGRHAQTVETLLRHGAHIN 762 Score = 38.9 bits (89), Expect = 0.001 Identities = 28/81 (34%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH AA+ GH+ L+ DG TA H AA GH + L+ ++ Sbjct: 639 TPLHVAAETGHTSTARLLLH-RGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVL 697 Query: 62 A-DLWGGTALYDAAENGELEV 81 A TAL+ AA +G EV Sbjct: 698 ARGPLNQTALHLAAAHGHSEV 718 Score = 38.5 bits (88), Expect = 0.001 Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 5/84 (5%) Query: 2 TPLHAAAQMGHSPVI-VWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGG-E 59 TP+H A Q G ++ + L DVSL Q KD H+AA +GH ++ L G Sbjct: 539 TPMHVACQHGQENIVRILLRRGVDVSL--QGKDAWLPLHYAAWQGHLPIVKLLAKQPGVS 596 Query: 60 ISAD-LWGGTALYDAAENGELEVS 82 ++A L G T L+ AA+ G V+ Sbjct: 597 VNAQTLDGRTPLHLAAQRGHYRVA 620 Score = 37.0 bits (84), Expect = 0.004 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH A + V+ L++ +S++ +D+D TA HFAA G LL ++ Sbjct: 473 TPLHMAVERRVRGVVELLLA-RKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVN 531 Query: 62 -ADLWGGTALYDAAENGE 78 D G T ++ A ++G+ Sbjct: 532 EVDFEGRTPMHVACQHGQ 549 Score = 26.2 bits (56), Expect = 7.2 Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 6/55 (10%) Query: 27 LSEQDKD-----GATATHFAASRGHSKVLSWLLLHGGEIS-ADLWGGTALYDAAE 75 L QD D GA+ H A G + WLLL+ + ++ G T L+ A E Sbjct: 426 LQPQDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVE 480 >gi|8051593 GA binding protein transcription factor, beta subunit 1 isoform beta 1 [Homo sapiens] Length = 395 Score = 50.1 bits (118), Expect = 5e-07 Identities = 32/81 (39%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 +PLH AAQ GH L+ VS + K T H AAS GH+ ++ LL HG +++ Sbjct: 40 SPLHLAAQYGHYSTTEVLLRA-GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVN 98 Query: 62 A-DLWGGTALYDAAENGELEV 81 A D+ TAL+ A E+ EV Sbjct: 99 AKDMLKMTALHWATEHNHQEV 119 >gi|8051595 GA binding protein transcription factor, beta subunit 1 isoform beta 2 [Homo sapiens] Length = 383 Score = 50.1 bits (118), Expect = 5e-07 Identities = 32/81 (39%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 +PLH AAQ GH L+ VS + K T H AAS GH+ ++ LL HG +++ Sbjct: 40 SPLHLAAQYGHYSTTEVLLRA-GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVN 98 Query: 62 A-DLWGGTALYDAAENGELEV 81 A D+ TAL+ A E+ EV Sbjct: 99 AKDMLKMTALHWATEHNHQEV 119 >gi|32483404 GA binding protein transcription factor, beta subunit 1 isoform gamma 2 [Homo sapiens] Length = 348 Score = 50.1 bits (118), Expect = 5e-07 Identities = 32/81 (39%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 +PLH AAQ GH L+ VS + K T H AAS GH+ ++ LL HG +++ Sbjct: 40 SPLHLAAQYGHYSTTEVLLRA-GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVN 98 Query: 62 A-DLWGGTALYDAAENGELEV 81 A D+ TAL+ A E+ EV Sbjct: 99 AKDMLKMTALHWATEHNHQEV 119 >gi|8051597 GA binding protein transcription factor, beta subunit 1 isoform gamma 1 [Homo sapiens] Length = 360 Score = 50.1 bits (118), Expect = 5e-07 Identities = 32/81 (39%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 +PLH AAQ GH L+ VS + K T H AAS GH+ ++ LL HG +++ Sbjct: 40 SPLHLAAQYGHYSTTEVLLRA-GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVN 98 Query: 62 A-DLWGGTALYDAAENGELEV 81 A D+ TAL+ A E+ EV Sbjct: 99 AKDMLKMTALHWATEHNHQEV 119 >gi|8051599 GA binding protein transcription factor, beta subunit 1 isoform gamma 2 [Homo sapiens] Length = 348 Score = 50.1 bits (118), Expect = 5e-07 Identities = 32/81 (39%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 +PLH AAQ GH L+ VS + K T H AAS GH+ ++ LL HG +++ Sbjct: 40 SPLHLAAQYGHYSTTEVLLRA-GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVN 98 Query: 62 A-DLWGGTALYDAAENGELEV 81 A D+ TAL+ A E+ EV Sbjct: 99 AKDMLKMTALHWATEHNHQEV 119 >gi|62988328 ankyrin repeat domain 50 [Homo sapiens] Length = 1429 Score = 49.3 bits (116), Expect = 8e-07 Identities = 32/81 (39%), Positives = 47/81 (58%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPL AA+ GH+ V+ L+ C +++ D+DG TA AA GH++V+S LL G ++ Sbjct: 580 TPLTLAARQGHTKVVNCLIGC-GANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVD 638 Query: 62 -ADLWGGTALYDAAENGELEV 81 AD TAL AA G ++ Sbjct: 639 CADADSRTALRAAAWGGHEDI 659 Score = 43.1 bits (100), Expect = 6e-05 Identities = 31/82 (37%), Positives = 41/82 (50%), Gaps = 2/82 (2%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 MTPL AA GH V+ L+ + D +G T AAS GH+ V++ LL G + Sbjct: 749 MTPLLVAAYEGHVDVVDLLLE-GGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAV 807 Query: 61 -SADLWGGTALYDAAENGELEV 81 S D G T L A+ G +EV Sbjct: 808 DSIDSEGRTVLSIASAQGNVEV 829 Score = 43.1 bits (100), Expect = 6e-05 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 2/79 (2%) Query: 4 LHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS-A 62 L +AA GH V+ L+ V + GATA AA GH V+ LL HG + + A Sbjct: 1016 LQSAAWQGHVKVVQLLIEHGAV-VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHA 1074 Query: 63 DLWGGTALYDAAENGELEV 81 D +G TA+ AA+NG ++ Sbjct: 1075 DQFGRTAMRVAAKNGHSQI 1093 Score = 42.7 bits (99), Expect = 7e-05 Identities = 32/81 (39%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T L +AA GH+ V+ L+ V + D D TA AA GH ++ LL HG E++ Sbjct: 613 TALRSAAWGGHTEVVSALLYA-GVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVN 671 Query: 62 -ADLWGGTALYDAAENGELEV 81 AD G TAL AA G E+ Sbjct: 672 KADNEGRTALIAAAYMGHREI 692 Score = 42.0 bits (97), Expect = 1e-04 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 2/74 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T L AAA GH +++ L+ +++ D +G TA AA GH +++ LL HG E++ Sbjct: 646 TALRAAAWGGHEDIVLNLLQ-HGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVN 704 Query: 62 -ADLWGGTALYDAA 74 D+ G TAL AA Sbjct: 705 HEDVDGRTALSVAA 718 Score = 40.0 bits (92), Expect = 5e-04 Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 4/82 (4%) Query: 2 TPLHAAAQMGHSPVIVWLVSC-TDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 T LH + GH ++ L++ DV+ ++ +K A + AA +GH KV+ L+ HG + Sbjct: 981 TALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQS--AAWQGHVKVVQLLIEHGAVV 1038 Query: 61 SADL-WGGTALYDAAENGELEV 81 G TAL AA+ G ++V Sbjct: 1039 DHTCNQGATALCIAAQEGHIDV 1060 Score = 34.3 bits (77), Expect = 0.027 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 2/75 (2%) Query: 8 AQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS-ADLWG 66 A GH+ V+ L+ + DKDG T AA GH V+ LL G ++ D G Sbjct: 723 ASKGHASVVSLLID-RGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNG 781 Query: 67 GTALYDAAENGELEV 81 T L AA G V Sbjct: 782 RTPLLAAASMGHASV 796 Score = 33.1 bits (74), Expect = 0.059 Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Query: 3 PLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA 62 P A+Q GH + L+ ++ ++ DG A AA GH ++ L HG +++ Sbjct: 883 PFILASQEGHYDCVQILLE-NKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNC 941 Query: 63 -DLWGGTALYDAAENGELEVS 82 D G LY A +L ++ Sbjct: 942 KDADGRPTLYILALENQLTMA 962 Score = 29.3 bits (64), Expect = 0.85 Identities = 16/57 (28%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Query: 26 SLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI-SADLWGGTALYDAAENGELEV 81 ++ D +G TA H + +GH +++ L+ + ++ +AD +AL AA G ++V Sbjct: 971 NVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKV 1027 >gi|223634006 hypothetical protein LOC441869 [Homo sapiens] Length = 399 Score = 48.1 bits (113), Expect = 2e-06 Identities = 42/117 (35%), Positives = 54/117 (46%), Gaps = 12/117 (10%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH A GH+P++ L+ + D+ G TA H AA GHS+V LL G + Sbjct: 76 TPLHLAVLRGHAPLVRLLLQ-RGAPVGAVDRAGRTALHEAAWHGHSRVAELLLQRGASAA 134 Query: 62 ADLWGG-TALYDAAENGELEVSA------GPGWGRAPSAGTALSARPCPGAGVPARG 111 A G T L+ AA G ++A GPG P+A A AR A A G Sbjct: 135 ARSGTGLTPLHWAAALGHTLLAARLLEAPGPG----PAAAEAEDARGWTAAHWAAAG 187 Score = 41.2 bits (95), Expect = 2e-04 Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 4/77 (5%) Query: 26 SLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLWGGTALYDAAENGE---LEV 81 S+ E+D G T H A RGH+ ++ LL G + A D G TAL++AA +G E+ Sbjct: 66 SVEERDHAGRTPLHLAVLRGHAPLVRLLLQRGAPVGAVDRAGRTALHEAAWHGHSRVAEL 125 Query: 82 SAGPGWGRAPSAGTALS 98 G A +GT L+ Sbjct: 126 LLQRGASAAARSGTGLT 142 Score = 41.2 bits (95), Expect = 2e-04 Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 4/83 (4%) Query: 2 TPLHAAAQMGHSPVI-VWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 T L AA +G S I V L D + +D+ G +A H AA+RGH + L+ G E+ Sbjct: 238 TALGLAAALGRSQDIEVLLGHGADPGI--RDRHGRSALHRAAARGHLLAVQLLVTQGAEV 295 Query: 61 SA-DLWGGTALYDAAENGELEVS 82 A D G T L+ A+ G +EV+ Sbjct: 296 DARDTLGLTPLHHASREGHVEVA 318 Score = 40.4 bits (93), Expect = 4e-04 Identities = 33/98 (33%), Positives = 44/98 (44%), Gaps = 7/98 (7%) Query: 4 LHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISAD 63 LH AA GH + LV+ + +D G T H A+ GH +V LL G ++ A Sbjct: 273 LHRAAARGHLLAVQLLVT-QGAEVDARDTLGLTPLHHASREGHVEVAGCLLDRGAQVDAT 331 Query: 64 LW-GGTALYDAAENGELEVSAGPGWGRAPSAGTALSAR 100 W T L+ AAE G GP G S G + + R Sbjct: 332 GWLRKTPLHLAAERGH-----GPTVGLLLSRGASPTLR 364 Score = 38.5 bits (88), Expect = 0.001 Identities = 40/123 (32%), Positives = 53/123 (43%), Gaps = 24/123 (19%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCT---DVSLSEQDKDGATATHFAASRGHSKVLSWLLLHG 57 +TPLH AA +GH+ + L+ + +D G TA H+AA+ G VL LL G Sbjct: 141 LTPLHWAAALGHTLLAARLLEAPGPGPAAAEAEDARGWTAAHWAAAGGRLAVLE-LLAAG 199 Query: 58 GEISADLWGGTALYDAAENGELEVSAGPGWGRA----PSAGTALSARPCPGAGVPARGRG 113 G A +G L V+A G G A + G + AR GAG A G Sbjct: 200 G--------------AGLDGALLVAAAAGRGAALRFLLARGARVDAR--DGAGATALGLA 243 Query: 114 RVL 116 L Sbjct: 244 AAL 246 Score = 32.3 bits (72), Expect = 0.10 Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Query: 4 LHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS-A 62 L AA G + +L++ + +D GATA AA+ G S+ + LL HG + Sbjct: 207 LLVAAAAGRGAALRFLLA-RGARVDARDGAGATALGLAAALGRSQDIEVLLGHGADPGIR 265 Query: 63 DLWGGTALYDAAENGEL 79 D G +AL+ AA G L Sbjct: 266 DRHGRSALHRAAARGHL 282 Score = 31.2 bits (69), Expect = 0.22 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 7/60 (11%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDG---ATATHFAASRGHSKVLSWLLLHG 57 +TPLH A++ GH V + C ++ D G T H AA RGH + LL G Sbjct: 303 LTPLHHASREGH----VEVAGCLLDRGAQVDATGWLRKTPLHLAAERGHGPTVGLLLSRG 358 >gi|24233530 ankyrin repeat domain 44 [Homo sapiens] Length = 919 Score = 48.1 bits (113), Expect = 2e-06 Identities = 30/81 (37%), Positives = 46/81 (56%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T LH AA GH ++ L++ +++ DK A H+AA GH V++ L+ HG E++ Sbjct: 117 TALHHAALNGHVEMVNLLLA-KGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVT 175 Query: 62 A-DLWGGTALYDAAENGELEV 81 D G T L+ AA NG++ V Sbjct: 176 CKDKKGYTPLHAAASNGQINV 196 Score = 47.0 bits (110), Expect = 4e-06 Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 2/76 (2%) Query: 4 LHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI-SA 62 LH AA MGH V+ L++ ++ +DK G T H AAS G V+ LL G EI Sbjct: 152 LHWAAYMGHLDVVALLIN-HGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEI 210 Query: 63 DLWGGTALYDAAENGE 78 +++G TAL+ A NG+ Sbjct: 211 NVYGNTALHIACYNGQ 226 Score = 44.3 bits (103), Expect = 3e-05 Identities = 35/86 (40%), Positives = 48/86 (55%), Gaps = 8/86 (9%) Query: 2 TPLHAAAQ---MGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGG 58 TPLH AA + + VI+ L+S +VS D+ G TA H AA GH ++++ LL G Sbjct: 84 TPLHVAAANKAVKCAEVIIPLLSSVNVS----DRGGRTALHHAALNGHVEMVNLLLAKGA 139 Query: 59 EISA-DLWGGTALYDAAENGELEVSA 83 I+A D AL+ AA G L+V A Sbjct: 140 NINAFDKKDRRALHWAAYMGHLDVVA 165 Score = 41.2 bits (95), Expect = 2e-04 Identities = 31/79 (39%), Positives = 38/79 (48%), Gaps = 2/79 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSL-SEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 TPLH A H L+ D S+ S +D G T AA H + L LL H + Sbjct: 781 TPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPV 840 Query: 61 SA-DLWGGTALYDAAENGE 78 +A D G TAL AAENG+ Sbjct: 841 NAVDNSGKTALMMAAENGQ 859 Score = 40.8 bits (94), Expect = 3e-04 Identities = 27/77 (35%), Positives = 36/77 (46%), Gaps = 1/77 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH AA H + + L+ ++ Q KDG + H A G L+ +GGEI Sbjct: 249 TPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEID 308 Query: 62 -ADLWGGTALYDAAENG 77 D G T L+ AA G Sbjct: 309 CVDKDGNTPLHVAARYG 325 Score = 40.8 bits (94), Expect = 3e-04 Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T LHAAA G+ I L S + ++DK G T H+AA+ H + L+ G ++ Sbjct: 382 TCLHAAAAGGNVECIKLLQS-SGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVN 440 Query: 62 -ADLWGGTALYDAA 74 D WG TAL+ AA Sbjct: 441 ETDDWGRTALHYAA 454 Score = 37.4 bits (85), Expect = 0.003 Identities = 30/83 (36%), Positives = 40/83 (48%), Gaps = 8/83 (9%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATA---THFAASRGHSKVLSWLLLHGG 58 TPLH AA+ GH L++ S ++ K G + H AA HS LL G Sbjct: 316 TPLHVAARYGHE----LLINTLRTSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGF 371 Query: 59 EI-SADLWGGTALYDAAENGELE 80 EI + D +G T L+ AA G +E Sbjct: 372 EIDTPDKFGRTCLHAAAAGGNVE 394 Score = 37.4 bits (85), Expect = 0.003 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLL 54 T LH GH + L+ +VS+ +D G T H+AA+RGH+ LS LL Sbjct: 680 TALHRGIMTGHEECVQMLLE-QEVSILCKDSRGRTPLHYAAARGHATWLSELL 731 Score = 35.0 bits (79), Expect = 0.016 Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLHAAA G V+ L++ V + E + G TA H A G V++ L+ +G ++ Sbjct: 183 TPLHAAASNGQINVVKHLLN-LGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVN 241 Score = 34.7 bits (78), Expect = 0.020 Identities = 18/47 (38%), Positives = 25/47 (53%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSK 48 T L AA+ G + + LV+ L+ +DKD T H A S+GH K Sbjct: 849 TALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACSKGHEK 895 Score = 33.9 bits (76), Expect = 0.035 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 3/82 (3%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTD--VSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGE 59 TPLHA+ GH+ + L+ D ++ +D G T A + GH +S LL Sbjct: 611 TPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEAN 670 Query: 60 I-SADLWGGTALYDAAENGELE 80 + + D+ G TAL+ G E Sbjct: 671 VDTVDILGCTALHRGIMTGHEE 692 Score = 31.2 bits (69), Expect = 0.22 Identities = 19/42 (45%), Positives = 25/42 (59%), Gaps = 1/42 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAAS 43 TPLH AA H I LV+ T +++E D G TA H+AA+ Sbjct: 415 TPLHYAAANCHFHCIETLVT-TGANVNETDDWGRTALHYAAA 455 Score = 30.8 bits (68), Expect = 0.29 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 2/76 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH AA +G + +I L+ + ++ +D T H A + + + L+ H +++ Sbjct: 18 TPLHVAAFLGDAEIIELLI-LSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVN 76 Query: 62 A-DLWGGTALYDAAEN 76 A D T L+ AA N Sbjct: 77 ARDKNWQTPLHVAAAN 92 Score = 29.3 bits (64), Expect = 0.85 Identities = 13/31 (41%), Positives = 20/31 (64%) Query: 24 DVSLSEQDKDGATATHFAASRGHSKVLSWLL 54 D + S +DK+G + H+AA+ GH + L LL Sbjct: 497 DANPSIRDKEGYNSIHYAAAYGHRQCLELLL 527 Score = 26.9 bits (58), Expect = 4.2 Identities = 12/29 (41%), Positives = 16/29 (55%) Query: 31 DKDGATATHFAASRGHSKVLSWLLLHGGE 59 DKDG T H AA GH +++ L G + Sbjct: 311 DKDGNTPLHVAARYGHELLINTLRTSGAD 339 >gi|17864094 feminization 1 homolog a [Homo sapiens] Length = 617 Score = 47.4 bits (111), Expect = 3e-06 Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPL AA GH ++ +LV L ++ G T + +GH ++ +LL G +++ Sbjct: 118 TPLRAACFDGHLEIVKYLVE-HKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVN 176 Query: 62 A-DLWGGTALYDAAENGELEV 81 + G TAL+D AE+G L++ Sbjct: 177 RKSVKGNTALHDCAESGSLDI 197 Score = 37.4 bits (85), Expect = 0.003 Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 9/89 (10%) Query: 2 TPLHAAAQMGHSPVIVWLVS-CT-------DVSLSEQDKDGATATHFAASRGHSKVLSWL 53 TPL AA+ GH ++ +L+ C+ V+ + +GA A++ GH KV+ L Sbjct: 43 TPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSL 102 Query: 54 LLHGGEI-SADLWGGTALYDAAENGELEV 81 L HG + + L T L A +G LE+ Sbjct: 103 LNHGASVNNTTLTNSTPLRAACFDGHLEI 131 >gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] Length = 4377 Score = 46.6 bits (109), Expect = 5e-06 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 2/82 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH +A++G + ++ L+ S + G T H +A GH V ++LL HG +S Sbjct: 501 TPLHISARLGKADIVQQLLQ-QGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLS 559 Query: 62 ADLWGG-TALYDAAENGELEVS 82 G T L+ AA+ G+LEV+ Sbjct: 560 ITTKKGFTPLHVAAKYGKLEVA 581 Score = 42.7 bits (99), Expect = 7e-05 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGE-I 60 TPLH A + V+ L+ S+ + G T H AA GH ++S L+ HG Sbjct: 402 TPLHIACKKNRIKVMELLLK-HGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPN 460 Query: 61 SADLWGGTALYDAAENGELEV 81 + ++ G TAL+ AA +G+ EV Sbjct: 461 TTNVRGETALHMAARSGQAEV 481 Score = 40.4 bits (93), Expect = 4e-04 Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 3/103 (2%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 +TP+H AA MGH ++ L+ S + + G TA H AA G ++V+ +L+ G ++ Sbjct: 434 LTPIHVAAFMGHVNIVSQLMH-HGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV 492 Query: 61 SADLWGG-TALYDAAENGELE-VSAGPGWGRAPSAGTALSARP 101 A T L+ +A G+ + V G +P+A T P Sbjct: 493 EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTP 535 Score = 36.6 bits (83), Expect = 0.005 Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 +TPLH A++ G++ ++ L+ + + +DG T H A GH +V+ LL I Sbjct: 269 ITPLHVASKRGNANMVKLLLD-RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPI 327 Query: 61 SADLWGGTALYDAAENGE 78 + G + A G+ Sbjct: 328 LSKTKNGLSPLHMATQGD 345 Score = 36.2 bits (82), Expect = 0.007 Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 +T LH AA GH V L+ + + + +G T H A + KV+ LL HG I Sbjct: 368 LTALHVAAHCGHYKVAKVLLD-KKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASI 426 Query: 61 SADLWGG-TALYDAAENGELEV 81 A G T ++ AA G + + Sbjct: 427 QAVTESGLTPIHVAAFMGHVNI 448 Score = 35.4 bits (80), Expect = 0.012 Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 4/77 (5%) Query: 7 AAQMGH-SPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI-SADL 64 AA+ GH + ++ + D+++ Q+ G A H A+ GH +V+S LL + +A Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQN--GLNALHLASKEGHVEVVSELLQREANVDAATK 105 Query: 65 WGGTALYDAAENGELEV 81 G TAL+ A+ G+ EV Sbjct: 106 KGNTALHIASLAGQAEV 122 Score = 35.0 bits (79), Expect = 0.016 Identities = 22/53 (41%), Positives = 28/53 (52%), Gaps = 1/53 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLL 54 TPLH +A+ GH V +L+ SLS K G T H AA G +V + LL Sbjct: 534 TPLHLSAREGHEDVAAFLLD-HGASLSITTKKGFTPLHVAAKYGKLEVANLLL 585 Score = 35.0 bits (79), Expect = 0.016 Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 6/83 (7%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHG---G 58 TPLH G+ ++ +L+ + ++ + K+G T H AA +GH+ +++ LL + Sbjct: 732 TPLHVGCHYGNIKIVNFLLQHS-AKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPN 790 Query: 59 EISADLWGGTALYDAAENGELEV 81 E++ + G TAL A G + V Sbjct: 791 ELTVN--GNTALGIARRLGYISV 811 Score = 34.7 bits (78), Expect = 0.020 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 2/81 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH AA G+ V L++ ++ ++ T H A+ RG++ ++ LL G +I Sbjct: 237 TPLHIAAHYGNINVATLLLNRA-AAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKID 295 Query: 62 ADLWGG-TALYDAAENGELEV 81 A G T L+ A +G +V Sbjct: 296 AKTRDGLTPLHCGARSGHEQV 316 Score = 34.3 bits (77), Expect = 0.027 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLL 54 TPL+ AAQ H V+ +L+ S S +DG T A +GH +V+S LL Sbjct: 142 TPLYMAAQENHLEVVKFLLD-NGASQSLATEDGFTPLAVALQQGHDQVVSLLL 193 Score = 34.3 bits (77), Expect = 0.027 Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 2/82 (2%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 +TPLH AA + V + L+ S K+G T H AA + + + LL +G + Sbjct: 599 LTPLHVAAHYDNQKVALLLLD-QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADA 657 Query: 61 SADLWGGTA-LYDAAENGELEV 81 +A G A ++ AA+ G +++ Sbjct: 658 NAVTRQGIASVHLAAQEGHVDM 679 Score = 32.7 bits (73), Expect = 0.077 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 2/82 (2%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 ++PLH A Q H + L+ +V + + D TA H AA GH KV LL Sbjct: 335 LSPLHMATQGDHLNCVQLLLQ-HNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANP 393 Query: 61 SAD-LWGGTALYDAAENGELEV 81 +A L G T L+ A + ++V Sbjct: 394 NAKALNGFTPLHIACKKNRIKV 415 Score = 32.0 bits (71), Expect = 0.13 Identities = 21/79 (26%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 4 LHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISAD 63 +H AAQ GH ++ L+ + +++ +K G T H AA V L+ G + A Sbjct: 668 VHLAAQEGHVDMVSLLLG-RNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQ 726 Query: 64 L-WGGTALYDAAENGELEV 81 G T L+ G +++ Sbjct: 727 TKMGYTPLHVGCHYGNIKI 745 Score = 31.6 bits (70), Expect = 0.17 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH AA+ + L+ + + G + H AA GH ++S LL ++ Sbjct: 633 TPLHIAAKKNQMDIATTLLEY-GADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVN 691 Query: 62 -ADLWGGTALYDAAENGELEVS 82 ++ G T L+ AA+ + V+ Sbjct: 692 LSNKSGLTPLHLAAQEDRVNVA 713 Score = 31.6 bits (70), Expect = 0.17 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWL 53 TPLH AAQ GH+ +I L+ + S +E +G TA A G+ V+ L Sbjct: 765 TPLHQAAQQGHTHIINVLLQ-NNASPNELTVNGNTALGIARRLGYISVVDTL 815 >gi|116534990 ankyrin-like protein 1 [Homo sapiens] Length = 1119 Score = 46.2 bits (108), Expect = 7e-06 Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 32/113 (28%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQ------------------------------ 30 MTPLH AA+ GH V+ L+ + LS+ Sbjct: 483 MTPLHLAAKNGHDKVVQLLLKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTD 542 Query: 31 --DKDGATATHFAASRGHSKVLSWLLLHGGEISADLWGGTALYDAAENGELEV 81 D+DG TA HFAA GH+K ++ LL H +I + + L+ A N EV Sbjct: 543 RLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEV 595 Score = 43.5 bits (101), Expect = 4e-05 Identities = 31/80 (38%), Positives = 39/80 (48%), Gaps = 6/80 (7%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVS----LSEQDKDGATATHFAASRGHSKVLSWLLLHG 57 +PLH AA G L+ D+S L+E D G T H AA GH KV+ LL G Sbjct: 448 SPLHFAASYGRINTCQRLLQ--DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKG 505 Query: 58 GEISADLWGGTALYDAAENG 77 +D G TAL+ A+ G Sbjct: 506 ALFLSDHNGWTALHHASMGG 525 Score = 36.2 bits (82), Expect = 0.007 Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 1/81 (1%) Query: 1 MTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGE- 59 M PLH A Q ++ V+ L+ + ++ + ++G TA A + +S+ L LL G + Sbjct: 132 MAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLKKGAKP 191 Query: 60 ISADLWGGTALYDAAENGELE 80 ++ WG ++ AA +G E Sbjct: 192 CKSNKWGCFPIHQAAFSGSKE 212 Score = 36.2 bits (82), Expect = 0.007 Identities = 30/84 (35%), Positives = 40/84 (47%), Gaps = 5/84 (5%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI- 60 TPLH A + G P V + +VS+ + KD + HFAAS G LL + Sbjct: 415 TPLHYACRQG-GPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTR 473 Query: 61 ---SADLWGGTALYDAAENGELEV 81 DL G T L+ AA+NG +V Sbjct: 474 LLNEGDLHGMTPLHLAAKNGHDKV 497 Score = 32.0 bits (71), Expect = 0.13 Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 13/104 (12%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TPLH A Q G +I + + +K TA HFAA++G ++++ L++ S Sbjct: 241 TPLHLAVQNGDLEMIKMCLD-NGAQIDPVEKGRCTAIHFAATQGATEIVK-LMISSYSGS 298 Query: 62 ADLWGGT-----------ALYDAAENGELEVSAGPGWGRAPSAG 94 D+ T +L+D E + +S G + S G Sbjct: 299 VDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEG 342 >gi|41327752 diabetes related ankyrin repeat protein [Homo sapiens] Length = 305 Score = 46.2 bits (108), Expect = 7e-06 Identities = 24/59 (40%), Positives = 32/59 (54%), Gaps = 1/59 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 TPLH A + H + L+ C L+ QDK+G TA H A G K + LLL+G E+ Sbjct: 212 TPLHVAVRTRHPDCLEHLIEC-GAHLNAQDKEGDTALHEAVRHGSYKAMKLLLLYGAEL 269 Score = 36.2 bits (82), Expect = 0.007 Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 2/77 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 TP+ A + GH ++ L++ ++ +DK G+T H A H L L+ G ++ Sbjct: 179 TPVFWACRGGHLVILKQLLN-QGARVNARDKIGSTPLHVAVRTRHPDCLEHLIECGAHLN 237 Query: 62 A-DLWGGTALYDAAENG 77 A D G TAL++A +G Sbjct: 238 AQDKEGDTALHEAVRHG 254 Score = 33.5 bits (75), Expect = 0.045 Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 1/52 (1%) Query: 31 DKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLWGGTALYDAAENGELEV 81 DK TA H+A +GHS++++ LL+ G + A DL T ++ A G L + Sbjct: 141 DKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGHLVI 192 >gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens] Length = 1721 Score = 45.8 bits (107), Expect = 9e-06 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T L AA++G+ V+++ + ++ +D G A H A +RG ++ LL +G +++ Sbjct: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490 Query: 62 ADLWGGT-ALYDAAENGELEV 81 GT L+DA EN LE+ Sbjct: 1491 CSAQDGTRPLHDAVENDHLEI 1511 >gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens] Length = 1050 Score = 45.8 bits (107), Expect = 9e-06 Identities = 27/72 (37%), Positives = 43/72 (59%), Gaps = 2/72 (2%) Query: 3 PLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA 62 PLH A Q GH V+ L+ ++ +++D G T +A S GH ++++ LL HG I+A Sbjct: 780 PLHLACQQGHFQVVKCLLD-SNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINA 838 Query: 63 -DLWGGTALYDA 73 + G TAL++A Sbjct: 839 SNNKGNTALHEA 850 Score = 35.8 bits (81), Expect = 0.009 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 2/55 (3%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLH 56 TPLH AA G + +I LVS ++ D GAT H A +G+ V + LLLH Sbjct: 465 TPLHVAAVCGQASLIDLLVS-KGAMVNATDYHGATPLHLACQKGYQSV-TLLLLH 517 Score = 34.3 bits (77), Expect = 0.027 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 1/58 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGE 59 TPLH A Q G+ V + L+ S QD +G T H A + GH + L+ + E Sbjct: 498 TPLHLACQKGYQSVTLLLLHYK-ASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVE 554 Score = 34.3 bits (77), Expect = 0.027 Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 +PLH AA G + +I L+ + ++ D A H A +GH +V+ LL + + Sbjct: 746 SPLHVAALHGRADLIPLLLK-HGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPN 804 Query: 62 -ADLWGGTALYDAAENGELEVSA 83 DL G T L A G E+ A Sbjct: 805 KKDLSGNTPLIYACSGGHHELVA 827 Score = 33.1 bits (74), Expect = 0.059 Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 1/59 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 TPL A GH ++ L+ S++ + G TA H A H V+ LLLHG + Sbjct: 812 TPLIYACSGGHHELVALLLQ-HGASINASNNKGNTALHEAVIEKHVFVVELLLLHGASV 869 Score = 27.3 bits (59), Expect = 3.2 Identities = 16/63 (25%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 20 VSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLWGGTALYDAAENGE 78 V + + ++ +DG++ H AA G + ++ LL HG A + L+ A + G Sbjct: 730 VPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGH 789 Query: 79 LEV 81 +V Sbjct: 790 FQV 792 >gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens] Length = 1755 Score = 45.8 bits (107), Expect = 9e-06 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T L AA++G+ V+++ + ++ +D G A H A +RG ++ LL +G +++ Sbjct: 1465 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1524 Query: 62 ADLWGGT-ALYDAAENGELEV 81 GT L+DA EN LE+ Sbjct: 1525 CSAQDGTRPLHDAVENDHLEI 1545 >gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens] Length = 1703 Score = 45.8 bits (107), Expect = 9e-06 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T L AA++G+ V+++ + ++ +D G A H A +RG ++ LL +G +++ Sbjct: 1413 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1472 Query: 62 ADLWGGT-ALYDAAENGELEV 81 GT L+DA EN LE+ Sbjct: 1473 CSAQDGTRPLHDAVENDHLEI 1493 >gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens] Length = 1721 Score = 45.8 bits (107), Expect = 9e-06 Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 1/81 (1%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS 61 T L AA++G+ V+++ + ++ +D G A H A +RG ++ LL +G +++ Sbjct: 1431 TLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVN 1490 Query: 62 ADLWGGT-ALYDAAENGELEV 81 GT L+DA EN LE+ Sbjct: 1491 CSAQDGTRPLHDAVENDHLEI 1511 >gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] Length = 983 Score = 45.4 bits (106), Expect = 1e-05 Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Query: 7 AAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLW 65 A + G + + L+ S ++ D +G TA H AA++GH + L ++ HG +++A D Sbjct: 29 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT 88 Query: 66 GGTALYDAAENGELE 80 G +AL+ AA+N E Sbjct: 89 GHSALHLAAKNSHHE 103 Score = 35.0 bits (79), Expect = 0.016 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Query: 4 LHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS-A 62 LH AA+ H I L+ + D G TA H+AA++G + + L H I+ Sbjct: 93 LHLAAKNSHHECIRKLLQ-SKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLK 151 Query: 63 DLWGGTALYDAAENGELEV 81 DL G L A +NG E+ Sbjct: 152 DLDGNIPLLLAVQNGHSEI 170 Score = 33.5 bits (75), Expect = 0.045 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 4/78 (5%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVS-LSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 T LH AA G + L C S ++ +D DG A GHS++ +LL HG ++ Sbjct: 124 TALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADV 181 Query: 61 -SADLWGGTALYDAAENG 77 S + G TAL A E G Sbjct: 182 NSRNKSGRTALMLACEIG 199 >gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] Length = 972 Score = 45.4 bits (106), Expect = 1e-05 Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Query: 7 AAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLW 65 A + G + + L+ S ++ D +G TA H AA++GH + L ++ HG +++A D Sbjct: 18 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT 77 Query: 66 GGTALYDAAENGELE 80 G +AL+ AA+N E Sbjct: 78 GHSALHLAAKNSHHE 92 Score = 35.0 bits (79), Expect = 0.016 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Query: 4 LHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS-A 62 LH AA+ H I L+ + D G TA H+AA++G + + L H I+ Sbjct: 82 LHLAAKNSHHECIRKLLQ-SKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLK 140 Query: 63 DLWGGTALYDAAENGELEV 81 DL G L A +NG E+ Sbjct: 141 DLDGNIPLLLAVQNGHSEI 159 Score = 33.5 bits (75), Expect = 0.045 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 4/78 (5%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVS-LSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 T LH AA G + L C S ++ +D DG A GHS++ +LL HG ++ Sbjct: 113 TALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADV 170 Query: 61 -SADLWGGTALYDAAENG 77 S + G TAL A E G Sbjct: 171 NSRNKSGRTALMLACEIG 188 >gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] Length = 951 Score = 45.4 bits (106), Expect = 1e-05 Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Query: 7 AAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLW 65 A + G + + L+ S ++ D +G TA H AA++GH + L ++ HG +++A D Sbjct: 26 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT 85 Query: 66 GGTALYDAAENGELE 80 G +AL+ AA+N E Sbjct: 86 GHSALHLAAKNSHHE 100 Score = 35.0 bits (79), Expect = 0.016 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Query: 4 LHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS-A 62 LH AA+ H I L+ + D G TA H+AA++G + + L H I+ Sbjct: 90 LHLAAKNSHHECIRKLLQ-SKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLK 148 Query: 63 DLWGGTALYDAAENGELEV 81 DL G L A +NG E+ Sbjct: 149 DLDGNIPLLLAVQNGHSEI 167 Score = 33.5 bits (75), Expect = 0.045 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 4/78 (5%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVS-LSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 T LH AA G + L C S ++ +D DG A GHS++ +LL HG ++ Sbjct: 121 TALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADV 178 Query: 61 -SADLWGGTALYDAAENG 77 S + G TAL A E G Sbjct: 179 NSRNKSGRTALMLACEIG 196 >gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] Length = 980 Score = 45.4 bits (106), Expect = 1e-05 Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Query: 7 AAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLW 65 A + G + + L+ S ++ D +G TA H AA++GH + L ++ HG +++A D Sbjct: 26 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT 85 Query: 66 GGTALYDAAENGELE 80 G +AL+ AA+N E Sbjct: 86 GHSALHLAAKNSHHE 100 Score = 35.0 bits (79), Expect = 0.016 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Query: 4 LHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS-A 62 LH AA+ H I L+ + D G TA H+AA++G + + L H I+ Sbjct: 90 LHLAAKNSHHECIRKLLQ-SKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLK 148 Query: 63 DLWGGTALYDAAENGELEV 81 DL G L A +NG E+ Sbjct: 149 DLDGNIPLLLAVQNGHSEI 167 Score = 33.5 bits (75), Expect = 0.045 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 4/78 (5%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVS-LSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 T LH AA G + L C S ++ +D DG A GHS++ +LL HG ++ Sbjct: 121 TALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADV 178 Query: 61 -SADLWGGTALYDAAENG 77 S + G TAL A E G Sbjct: 179 NSRNKSGRTALMLACEIG 196 >gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] Length = 980 Score = 45.4 bits (106), Expect = 1e-05 Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Query: 7 AAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEISA-DLW 65 A + G + + L+ S ++ D +G TA H AA++GH + L ++ HG +++A D Sbjct: 26 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT 85 Query: 66 GGTALYDAAENGELE 80 G +AL+ AA+N E Sbjct: 86 GHSALHLAAKNSHHE 100 Score = 35.0 bits (79), Expect = 0.016 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Query: 4 LHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATATHFAASRGHSKVLSWLLLHGGEIS-A 62 LH AA+ H I L+ + D G TA H+AA++G + + L H I+ Sbjct: 90 LHLAAKNSHHECIRKLLQ-SKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLK 148 Query: 63 DLWGGTALYDAAENGELEV 81 DL G L A +NG E+ Sbjct: 149 DLDGNIPLLLAVQNGHSEI 167 Score = 33.5 bits (75), Expect = 0.045 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 4/78 (5%) Query: 2 TPLHAAAQMGHSPVIVWLVSCTDVS-LSEQDKDGATATHFAASRGHSKVLSWLLLHGGEI 60 T LH AA G + L C S ++ +D DG A GHS++ +LL HG ++ Sbjct: 121 TALHYAAAQGCLQAVQIL--CEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADV 178 Query: 61 -SADLWGGTALYDAAENG 77 S + G TAL A E G Sbjct: 179 NSRNKSGRTALMLACEIG 196 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.130 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 5,688,347 Number of Sequences: 37866 Number of extensions: 269963 Number of successful extensions: 2509 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 260 Number of HSP's successfully gapped in prelim test: 100 Number of HSP's that attempted gapping in prelim test: 1357 Number of HSP's gapped (non-prelim): 1059 length of query: 127 length of database: 18,247,518 effective HSP length: 90 effective length of query: 37 effective length of database: 14,839,578 effective search space: 549064386 effective search space used: 549064386 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.