Guide to the Human Genome
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Search of human proteins with 118572588

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118572588 cyclin F [Homo sapiens]
         (786 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118572588 cyclin F [Homo sapiens]                                 1593   0.0  
gi|161377472 cyclin A1 isoform c [Homo sapiens]                       112   1e-24
gi|161377470 cyclin A1 isoform c [Homo sapiens]                       112   1e-24
gi|161377468 cyclin A1 isoform b [Homo sapiens]                       112   1e-24
gi|4502611 cyclin A1 isoform a [Homo sapiens]                         112   1e-24
gi|4502613 cyclin A [Homo sapiens]                                    107   4e-23
gi|90669307 cyclin B3 isoform 3 [Homo sapiens]                         90   7e-18
gi|14327896 cyclin B1 [Homo sapiens]                                   89   2e-17
gi|4757930 cyclin B2 [Homo sapiens]                                    82   2e-15
gi|16306525 cyclin B3 isoform 1 [Homo sapiens]                         71   3e-12
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho...    71   4e-12
gi|4502617 cyclin D2 [Homo sapiens]                                    62   3e-09
gi|16950655 cyclin D1 [Homo sapiens]                                   60   1e-08
gi|17318565 cyclin E2 [Homo sapiens]                                   52   2e-06
gi|153791755 cyclin domain containing [Homo sapiens]                   50   8e-06
gi|17318559 cyclin E1 isoform 1 [Homo sapiens]                         49   2e-05
gi|17318561 cyclin E1 isoform 2 [Homo sapiens]                         49   2e-05
gi|197276674 cyclin J isoform 1 [Homo sapiens]                         49   2e-05
gi|4502619 cyclin D3 isoform 2 [Homo sapiens]                          42   0.002
gi|40254889 cyclin J isoform 2 [Homo sapiens]                          40   0.008
gi|197276676 cyclin J isoform 3 [Homo sapiens]                         40   0.011
gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofor...    39   0.014
gi|61966703 NHS-like 2 [Homo sapiens]                                  39   0.019
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                37   0.054
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                37   0.054
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                37   0.054
gi|187608312 cyclin N-terminal domain containing 1 [Homo sapiens]      37   0.071
gi|5031767 heat shock transcription factor 1 [Homo sapiens]            36   0.12 
gi|5031703 Ras-GTPase-activating protein SH3-domain-binding prot...    36   0.16 
gi|38327552 Ras-GTPase-activating protein SH3-domain-binding pro...    36   0.16 

>gi|118572588 cyclin F [Homo sapiens]
          Length = 786

 Score = 1593 bits (4124), Expect = 0.0
 Identities = 786/786 (100%), Positives = 786/786 (100%)

Query: 1   MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHS 60
           MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHS
Sbjct: 1   MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHS 60

Query: 61  QLKDLVDNHASVWACASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSD 120
           QLKDLVDNHASVWACASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSD
Sbjct: 61  QLKDLVDNHASVWACASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSD 120

Query: 121 EARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQR 180
           EARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQR
Sbjct: 121 EARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQR 180

Query: 181 THKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRC 240
           THKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRC
Sbjct: 181 THKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRC 240

Query: 241 LHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVSKQQVFS 300
           LHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVSKQQVFS
Sbjct: 241 LHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVSKQQVFS 300

Query: 301 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM 360
           VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM
Sbjct: 301 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM 360

Query: 361 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL 420
           VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL
Sbjct: 361 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL 420

Query: 421 VPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGF 480
           VPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGF
Sbjct: 421 VPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGF 480

Query: 481 SYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQEEVLSYSQLCAAL 540
           SYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQEEVLSYSQLCAAL
Sbjct: 481 SYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQEEVLSYSQLCAAL 540

Query: 541 GVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENSLQEDRGSFVTTPTAELSSQEETL 600
           GVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENSLQEDRGSFVTTPTAELSSQEETL
Sbjct: 541 GVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENSLQEDRGSFVTTPTAELSSQEETL 600

Query: 601 LGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDVTVVYLNPEQHCCQESSDEEACP 660
           LGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDVTVVYLNPEQHCCQESSDEEACP
Sbjct: 601 LGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDVTVVYLNPEQHCCQESSDEEACP 660

Query: 661 EDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASPTSSVDGGLGA 720
           EDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASPTSSVDGGLGA
Sbjct: 661 EDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASPTSSVDGGLGA 720

Query: 721 LPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQQVKRINLCIHSEEEDMN 780
           LPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQQVKRINLCIHSEEEDMN
Sbjct: 721 LPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQQVKRINLCIHSEEEDMN 780

Query: 781 LGLVRL 786
           LGLVRL
Sbjct: 781 LGLVRL 786


>gi|161377472 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score =  112 bits (281), Expect = 1e-24
 Identities = 91/333 (27%), Positives = 153/333 (45%), Gaps = 20/333 (6%)

Query: 200 EEKQQQAHDLFEEAAHQG----CLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGC 255
           +E  +Q  D++ +   QG    C     + +E     D       LH    L D+     
Sbjct: 84  QEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHF---LLDFNTVSP 140

Query: 256 WEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVS-----KQQVFSVQKGLNDTMR 310
                SL     + + LG +V   +E   +++Q  +        K      Q  + + MR
Sbjct: 141 MLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMR 200

Query: 311 YILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE 370
            IL+DWLVEV       +  L+L V  +DR+L    V R +LQL+G A M++ +++    
Sbjct: 201 TILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIY 260

Query: 371 ILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHL 430
              + E V++TD+TY    L++M   ++  L   + VPT   +    L    V +RT++L
Sbjct: 261 PPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL 320

Query: 431 CSFLCELSLLHTS-LSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCV 489
             ++ ELSLL       Y P+ +AAAA  LA  T  +   W   L   TG+S  +++PC+
Sbjct: 321 AKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNK-HFWPETLAAFTGYSLSEIVPCL 379

Query: 490 LSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRY 522
             LHK   + D P   +Q    A++++++  +Y
Sbjct: 380 SELHKA--YLDIPHRPQQ----AIREKYKASKY 406


>gi|161377470 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score =  112 bits (281), Expect = 1e-24
 Identities = 91/333 (27%), Positives = 153/333 (45%), Gaps = 20/333 (6%)

Query: 200 EEKQQQAHDLFEEAAHQG----CLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGC 255
           +E  +Q  D++ +   QG    C     + +E     D       LH    L D+     
Sbjct: 84  QEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHF---LLDFNTVSP 140

Query: 256 WEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVS-----KQQVFSVQKGLNDTMR 310
                SL     + + LG +V   +E   +++Q  +        K      Q  + + MR
Sbjct: 141 MLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMR 200

Query: 311 YILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE 370
            IL+DWLVEV       +  L+L V  +DR+L    V R +LQL+G A M++ +++    
Sbjct: 201 TILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIY 260

Query: 371 ILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHL 430
              + E V++TD+TY    L++M   ++  L   + VPT   +    L    V +RT++L
Sbjct: 261 PPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL 320

Query: 431 CSFLCELSLLHTS-LSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCV 489
             ++ ELSLL       Y P+ +AAAA  LA  T  +   W   L   TG+S  +++PC+
Sbjct: 321 AKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNK-HFWPETLAAFTGYSLSEIVPCL 379

Query: 490 LSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRY 522
             LHK   + D P   +Q    A++++++  +Y
Sbjct: 380 SELHKA--YLDIPHRPQQ----AIREKYKASKY 406


>gi|161377468 cyclin A1 isoform b [Homo sapiens]
          Length = 464

 Score =  112 bits (281), Expect = 1e-24
 Identities = 91/333 (27%), Positives = 153/333 (45%), Gaps = 20/333 (6%)

Query: 200 EEKQQQAHDLFEEAAHQG----CLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGC 255
           +E  +Q  D++ +   QG    C     + +E     D       LH    L D+     
Sbjct: 127 QEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHF---LLDFNTVSP 183

Query: 256 WEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVS-----KQQVFSVQKGLNDTMR 310
                SL     + + LG +V   +E   +++Q  +        K      Q  + + MR
Sbjct: 184 MLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMR 243

Query: 311 YILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE 370
            IL+DWLVEV       +  L+L V  +DR+L    V R +LQL+G A M++ +++    
Sbjct: 244 TILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIY 303

Query: 371 ILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHL 430
              + E V++TD+TY    L++M   ++  L   + VPT   +    L    V +RT++L
Sbjct: 304 PPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL 363

Query: 431 CSFLCELSLLHTS-LSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCV 489
             ++ ELSLL       Y P+ +AAAA  LA  T  +   W   L   TG+S  +++PC+
Sbjct: 364 AKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNK-HFWPETLAAFTGYSLSEIVPCL 422

Query: 490 LSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRY 522
             LHK   + D P   +Q    A++++++  +Y
Sbjct: 423 SELHKA--YLDIPHRPQQ----AIREKYKASKY 449


>gi|4502611 cyclin A1 isoform a [Homo sapiens]
          Length = 465

 Score =  112 bits (281), Expect = 1e-24
 Identities = 91/333 (27%), Positives = 153/333 (45%), Gaps = 20/333 (6%)

Query: 200 EEKQQQAHDLFEEAAHQG----CLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGC 255
           +E  +Q  D++ +   QG    C     + +E     D       LH    L D+     
Sbjct: 128 QEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHF---LLDFNTVSP 184

Query: 256 WEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVS-----KQQVFSVQKGLNDTMR 310
                SL     + + LG +V   +E   +++Q  +        K      Q  + + MR
Sbjct: 185 MLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMR 244

Query: 311 YILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE 370
            IL+DWLVEV       +  L+L V  +DR+L    V R +LQL+G A M++ +++    
Sbjct: 245 TILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIY 304

Query: 371 ILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHL 430
              + E V++TD+TY    L++M   ++  L   + VPT   +    L    V +RT++L
Sbjct: 305 PPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL 364

Query: 431 CSFLCELSLLHTS-LSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCV 489
             ++ ELSLL       Y P+ +AAAA  LA  T  +   W   L   TG+S  +++PC+
Sbjct: 365 AKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNK-HFWPETLAAFTGYSLSEIVPCL 423

Query: 490 LSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRY 522
             LHK   + D P   +Q    A++++++  +Y
Sbjct: 424 SELHKA--YLDIPHRPQQ----AIREKYKASKY 450


>gi|4502613 cyclin A [Homo sapiens]
          Length = 432

 Score =  107 bits (267), Expect = 4e-23
 Identities = 72/227 (31%), Positives = 120/227 (52%), Gaps = 9/227 (3%)

Query: 302 QKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMV 361
           Q  + ++MR IL+DWLVEV       +  LHL V  +DR+L    V R +LQL+G A M+
Sbjct: 203 QPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAML 262

Query: 362 ICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDY-KEVLLTL 420
           + ++F       + E V++TD+TY  + ++RM   ++  L   +  PTV  +  +  L  
Sbjct: 263 LASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQ 322

Query: 421 VPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTG 479
            P   + + L  FL ELSL+       Y P+ +A AA  LA  T    Q W   L   TG
Sbjct: 323 QPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYT-VTGQSWPESLIRKTG 381

Query: 480 FSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEIS 526
           ++ E L PC++ LH+   +  AP+  +Q    ++++++++ +Y  +S
Sbjct: 382 YTLESLKPCLMDLHQT--YLKAPQHAQQ----SIREKYKNSKYHGVS 422


>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
          Length = 1395

 Score = 90.1 bits (222), Expect = 7e-18
 Identities = 56/190 (29%), Positives = 96/190 (50%), Gaps = 1/190 (0%)

Query: 305  LNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICT 364
            +   MR IL+DWLVEV    + T   L+L V+ VD YL + +  + +LQLLG    +I  
Sbjct: 1156 ITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAA 1215

Query: 365  RFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVE 424
            +F       + + V++ D+ Y+  +++ M   I++ L+  I +P    +       +   
Sbjct: 1216 KFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTN 1275

Query: 425  LRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYED 484
            ++T  L  ++CE++L          ++LAAA+LLLA L   +   W   L   +G+S  +
Sbjct: 1276 MKTLTLSRYICEMTLQEYHYVQEKASKLAAASLLLA-LYMKKLGYWVPFLEHYSGYSISE 1334

Query: 485  LIPCVLSLHK 494
            L P V  L+K
Sbjct: 1335 LHPLVRQLNK 1344


>gi|14327896 cyclin B1 [Homo sapiens]
          Length = 433

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 60/228 (26%), Positives = 112/228 (49%), Gaps = 9/228 (3%)

Query: 273 GLEVRASSEIVCQLFQASQAVSKQQV----FSVQKGLNDTMRYILIDWLVEVATMKDFTS 328
           G +    SE V  ++   + + ++Q     + + + +   MR ILIDWLV+V        
Sbjct: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQ 220

Query: 329 LCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYE 388
             +++TV  +DR+++   VP+  LQL+G+  M I +++       I +  ++TDNTY   
Sbjct: 221 ETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKH 280

Query: 389 DLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYA 448
            + +M  +I+ AL   +  P  + +      +  V++    L  +L EL++L   +  + 
Sbjct: 281 QIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFP 340

Query: 449 PARLAAAALLLAR--LTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHK 494
           P+++AA A  LA   L +G+   WT  L     ++ E L+P +  L K
Sbjct: 341 PSQIAAGAFCLALKILDNGE---WTPTLQHYLSYTEESLLPVMQHLAK 385


>gi|4757930 cyclin B2 [Homo sapiens]
          Length = 398

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 51/192 (26%), Positives = 100/192 (52%), Gaps = 1/192 (0%)

Query: 303 KGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVI 362
           + +N  MR IL+DWLV+V +        L++ V  +DR+L+ + V R +LQL+GI  +++
Sbjct: 159 RDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLL 218

Query: 363 CTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVP 422
            +++       I + V++TDN Y    +  M   I+  L+ ++  P  + +         
Sbjct: 219 ASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGE 278

Query: 423 VELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSY 482
           V++    L  +L EL+L+   +  Y P+++AAAA  L++   GQ + W  +    TG++ 
Sbjct: 279 VDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLGQGK-WNLKQQYYTGYTE 337

Query: 483 EDLIPCVLSLHK 494
            +++  +  + K
Sbjct: 338 NEVLEVMQHMAK 349


>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
          Length = 291

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 46/170 (27%), Positives = 84/170 (49%), Gaps = 1/170 (0%)

Query: 325 DFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNT 384
           + T   L+L V+ VD YL + +  + +LQLLG    +I  +F       + + V++ D+ 
Sbjct: 72  EMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDN 131

Query: 385 YKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTSL 444
           Y+  +++ M   I++ L+  I +P    +       +   ++T  L  ++CE++L     
Sbjct: 132 YQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYHY 191

Query: 445 SAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHK 494
                ++LAAA+LLLA L   +   W   L   +G+S  +L P V  L+K
Sbjct: 192 VQEKASKLAAASLLLA-LYMKKLGYWVPFLEHYSGYSISELHPLVRQLNK 240


>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 307

 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 49/167 (29%), Positives = 82/167 (49%), Gaps = 1/167 (0%)

Query: 300 SVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIAC 359
           ++ + +   MR +++DWLV+V          L+L V  +D YL    V  +RLQLLG+AC
Sbjct: 98  ALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVAC 157

Query: 360 MVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLT 419
           + +  +     +        L+ +++   +L+R    I+S L+ ++  P  +    +L  
Sbjct: 158 LFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAA 217

Query: 420 LVPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLA-RLTHG 465
           L     +   L ++  ELSLL    + + P R AAAAL LA RL  G
Sbjct: 218 LAGSSPQVMLLATYFLELSLLEAEAAGWEPGRRAAAALSLAHRLLDG 264


>gi|4502617 cyclin D2 [Homo sapiens]
          Length = 289

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 54/235 (22%), Positives = 105/235 (44%), Gaps = 11/235 (4%)

Query: 301 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM 360
           VQK +   MR ++  W++EV   +        L +  +DR+L     P+  LQLLG  CM
Sbjct: 47  VQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCM 106

Query: 361 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL 420
            + ++      LT  +    TDN+ K ++L+     ++  L+  +   T  D+ E +L  
Sbjct: 107 FLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRK 166

Query: 421 VP-----VELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLW 475
           +P     + L  +H  +F+  L       + Y P+ +A  ++  A     Q +    ++ 
Sbjct: 167 LPQQREKLSLIRKHAQTFIA-LCATDFKFAMYPPSMIATGSVGAAICGLQQDE----EVS 221

Query: 476 DLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQEEV 530
            LT  +  +L+  + +    C      +    V L +++Q  +D+R G  S++E+
Sbjct: 222 SLTCDALTELLAKITNTDVDCL-KACQEQIEAVLLNSLQQYRQDQRDGSKSEDEL 275


>gi|16950655 cyclin D1 [Homo sapiens]
          Length = 295

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 44/165 (26%), Positives = 81/165 (49%), Gaps = 6/165 (3%)

Query: 301 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM 360
           VQK +  +MR I+  W++EV   +        L +  +DR+L    V + RLQLLG  CM
Sbjct: 48  VQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCM 107

Query: 361 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL 420
            + ++      LT  +    TDN+ + E+L++M   +V+ L+  +   T  D+ E  L+ 
Sbjct: 108 FVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSK 167

Query: 421 VP-----VELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLA 460
           +P      ++  +H  +F+  L        +  P+ +AA +++ A
Sbjct: 168 MPEAEENKQIIRKHAQTFVA-LCATDVKFISNPPSMVAAGSVVAA 211


>gi|17318565 cyclin E2 [Homo sapiens]
          Length = 404

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 35/134 (26%), Positives = 67/134 (50%), Gaps = 1/134 (0%)

Query: 286 LFQASQAVSKQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRY-LRR 344
           L + S+ V  +    +   L   MR IL+DWL+EV  +        +L  +  DR+ L +
Sbjct: 118 LKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQ 177

Query: 345 RLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGK 404
           + + +  LQL+GI  + I ++        ++E  ++TD     ED++RM   I+ AL+ +
Sbjct: 178 KDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWE 237

Query: 405 IRVPTVVDYKEVLL 418
           +   T++ +  + L
Sbjct: 238 LCPVTIISWLNLFL 251


>gi|153791755 cyclin domain containing [Homo sapiens]
          Length = 350

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 56/227 (24%), Positives = 94/227 (41%), Gaps = 16/227 (7%)

Query: 271 QLGLEVRASSEIVCQLFQASQA--VSKQQVFSVQKGLNDTMRYILIDWLVEVATM--KDF 326
           QL L+        C  F+ +Q      ++  + Q  +    R  L+ WL+ V       F
Sbjct: 92  QLDLQTFRDYGQSCYAFRKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSF 151

Query: 327 TSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYK 386
            SLCL  TV  +DR+L    V     QLLG+  ++I  + +      +++ + L    + 
Sbjct: 152 ESLCL--TVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFS 209

Query: 387 YEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVE---------LRTQHLCSFLCEL 437
            + L  +   ++  L   +  PT+  + E   T   VE         L  Q L   + EL
Sbjct: 210 RQQLCNLECIVLHKLHFTLGAPTISFFLE-HFTHARVEAGQAEASEALEAQALARGVAEL 268

Query: 438 SLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYED 484
           SL   + ++Y+P+ LA   L LA      ++P   +L D    + ED
Sbjct: 269 SLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRLGDHPEAALED 315


>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
          Length = 410

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 44/167 (26%), Positives = 76/167 (45%), Gaps = 16/167 (9%)

Query: 305 LNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYL-RRRLVPRYRLQLLGIACMVIC 363
           L   MR IL+DWL+EV  +        +L  +  DRY+  +  V +  LQL+GI+ + I 
Sbjct: 140 LQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIA 199

Query: 364 TRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVV------------ 411
            +        + +  ++TD     ++++ M   I+ AL+ ++   T+V            
Sbjct: 200 AKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYL 259

Query: 412 -DYKEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAAL 457
            D  EVLL   P ++  Q   + L +L +L      +    LAA+AL
Sbjct: 260 NDLHEVLLPQYPQQIFIQ--IAELLDLCVLDVDCLEFPYGILAASAL 304


>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
          Length = 395

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 44/167 (26%), Positives = 76/167 (45%), Gaps = 16/167 (9%)

Query: 305 LNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYL-RRRLVPRYRLQLLGIACMVIC 363
           L   MR IL+DWL+EV  +        +L  +  DRY+  +  V +  LQL+GI+ + I 
Sbjct: 125 LQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIA 184

Query: 364 TRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVV------------ 411
            +        + +  ++TD     ++++ M   I+ AL+ ++   T+V            
Sbjct: 185 AKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYL 244

Query: 412 -DYKEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAAL 457
            D  EVLL   P ++  Q   + L +L +L      +    LAA+AL
Sbjct: 245 NDLHEVLLPQYPQQIFIQ--IAELLDLCVLDVDCLEFPYGILAASAL 289


>gi|197276674 cyclin J isoform 1 [Homo sapiens]
          Length = 383

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 41/196 (20%), Positives = 88/196 (44%), Gaps = 26/196 (13%)

Query: 320 VATMKDFTSLC---LHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE-----I 371
           +A + +  +LC    HL V  +D ++ R  +   +L L+ ++C+++ ++F  KE     +
Sbjct: 47  IAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKL 106

Query: 372 LTIREAVWLTDNTYKY--EDLVRMMGEIVSALEGKIRVPTVVDYKEVLLT---------- 419
             +     +T+       ++L+ M   ++   +  + +PT   + E  L+          
Sbjct: 107 EQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHD 166

Query: 420 ------LVPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQ 473
                 L   +L       +  E+SL   +   YAP+ +AAA +  +R+    +  W T+
Sbjct: 167 GWPMICLEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTR 226

Query: 474 LWDLTGFSYEDLIPCV 489
           L  LT +S++ L+ C+
Sbjct: 227 LHRLTAYSWDFLVQCI 242


>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
          Length = 292

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 6/162 (3%)

Query: 301 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM 360
           VQ+ +   MR +L  W++EV   +        L +  +DRYL      + +LQLLG  CM
Sbjct: 48  VQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCM 107

Query: 361 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL 420
           ++ ++      LTI +    TD+      L      ++  L+  +      D+   +L  
Sbjct: 108 LLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHR 167

Query: 421 VPV-----ELRTQHLCSFLCELSLLHTSLSAYAPARLAAAAL 457
           + +      L  +H  +FL  L     + + Y P+ +A  ++
Sbjct: 168 LSLPRDRQALVKKHAQTFLA-LCATDYTFAMYPPSMIATGSI 208


>gi|40254889 cyclin J isoform 2 [Homo sapiens]
          Length = 372

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 38/186 (20%), Positives = 84/186 (45%), Gaps = 17/186 (9%)

Query: 320 VATMKDFTSLC---LHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE-----I 371
           +A + +  +LC    HL V  +D ++ R  +   +L L+ ++C+++ ++F  KE     +
Sbjct: 47  IAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKL 106

Query: 372 LTIREAVWLTDN--TYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQH 429
             +     +T+       ++L+ M   ++   +  + +PT   + E  L+    E     
Sbjct: 107 EQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHD 166

Query: 430 LCSFLCELSLLHTSLSAYA------PARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYE 483
               +C L      ++ YA        ++AAA +  +R+    +  W T+L  LT +S++
Sbjct: 167 GWPMIC-LEKTKLYMAKYADYFLEVSLQVAAACVASSRIILRLSPTWPTRLHRLTAYSWD 225

Query: 484 DLIPCV 489
            L+ C+
Sbjct: 226 FLVQCI 231


>gi|197276676 cyclin J isoform 3 [Homo sapiens]
          Length = 371

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 39/185 (21%), Positives = 83/185 (44%), Gaps = 16/185 (8%)

Query: 320 VATMKDFTSLC---LHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE-----I 371
           +A + +  +LC    HL V  +D ++ R  +   +L L+ ++C+++ ++F  KE     +
Sbjct: 47  IAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKL 106

Query: 372 LTIREAVWLTDN--TYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQH 429
             +     +T+       ++L+ M   ++   +  + +PT   + E  L+    E     
Sbjct: 107 EQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHD 166

Query: 430 LCSFLCELSLLHTSLSAYAPARL-----AAAALLLARLTHGQTQPWTTQLWDLTGFSYED 484
               +C L      ++ YA   L     AAA +  +R+    +  W T+L  LT +S++ 
Sbjct: 167 GWPMIC-LEKTKLYMAKYADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDF 225

Query: 485 LIPCV 489
           L+ C+
Sbjct: 226 LVQCI 230


>gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform a
           [Homo sapiens]
          Length = 475

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 36/145 (24%), Positives = 67/145 (46%), Gaps = 8/145 (5%)

Query: 79  QELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEARAEVNGLKASRFFSLA 138
           +EL  S G LK F    +       +  G A+     ++V+D+A A +NG++      L 
Sbjct: 276 KELLTSFGPLKAFNLVKDSAT---GLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLV 332

Query: 139 ERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQRTHKASILHCLGRVL--SL 196
           +R +VGA       + PP +++ +     V   + ++ Q+   H   +L  +  VL   L
Sbjct: 333 QRASVGAKNA--TLVSPPSTINQTPVTLQVPGLMSSQVQM-GGHPTEVLCLMNMVLPEEL 389

Query: 197 FEDEEKQQQAHDLFEEAAHQGCLTS 221
            +DEE ++   D+ +E +  G + S
Sbjct: 390 LDDEEYEEIVEDVRDECSKYGLVKS 414


>gi|61966703 NHS-like 2 [Homo sapiens]
          Length = 709

 Score = 38.9 bits (89), Expect = 0.019
 Identities = 36/116 (31%), Positives = 52/116 (44%), Gaps = 17/116 (14%)

Query: 651 QESSDEEACPEDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVS-TAS 709
           Q SS+  A P       P  L+++ +      P       R PG    +SGYSS S T +
Sbjct: 304 QGSSESLASPSTSRATTPSQLSIEVEAREISSP------GRPPGLMSPSSGYSSQSETPT 357

Query: 710 PTSSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQQV 765
           PT S+   LG LP P+S +        +P   + RKS L   PP+ P    P+ ++
Sbjct: 358 PTVSMSLTLGHLPPPSSSV------RVRPVVPE-RKSSL---PPTSPMEKFPKSRL 403


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 37.4 bits (85), Expect = 0.054
 Identities = 29/112 (25%), Positives = 42/112 (37%), Gaps = 6/112 (5%)

Query: 653 SSDEEACPEDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASP-T 711
           S+  +A P    P +  A       P  P   P   +S  P +        S +T +P +
Sbjct: 196 SATTQAPPSSSAPPETTAAP-----PTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLS 250

Query: 712 SSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQ 763
           SS      A+P   S  +LD  S + P    A         P+PP S  PQ+
Sbjct: 251 SSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQE 302


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 37.4 bits (85), Expect = 0.054
 Identities = 29/112 (25%), Positives = 42/112 (37%), Gaps = 6/112 (5%)

Query: 653 SSDEEACPEDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASP-T 711
           S+  +A P    P +  A       P  P   P   +S  P +        S +T +P +
Sbjct: 196 SATTQAPPSSSAPPETTAAP-----PTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLS 250

Query: 712 SSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQ 763
           SS      A+P   S  +LD  S + P    A         P+PP S  PQ+
Sbjct: 251 SSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQE 302


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 37.4 bits (85), Expect = 0.054
 Identities = 29/112 (25%), Positives = 42/112 (37%), Gaps = 6/112 (5%)

Query: 653 SSDEEACPEDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASP-T 711
           S+  +A P    P +  A       P  P   P   +S  P +        S +T +P +
Sbjct: 196 SATTQAPPSSSAPPETTAAP-----PTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLS 250

Query: 712 SSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQ 763
           SS      A+P   S  +LD  S + P    A         P+PP S  PQ+
Sbjct: 251 SSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQE 302


>gi|187608312 cyclin N-terminal domain containing 1 [Homo sapiens]
          Length = 330

 Score = 37.0 bits (84), Expect = 0.071
 Identities = 47/193 (24%), Positives = 85/193 (44%), Gaps = 29/193 (15%)

Query: 287 FQASQAVSKQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVD------- 339
           F+  Q V    + S Q  L  ++ Y  ++ ++E   +K   ++C   T++  D       
Sbjct: 50  FREPQIVEFVFLLSEQWCLEKSVSYQAVE-ILERFMVKQAENICRQATIQPRDNKRESQN 108

Query: 340 -RYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKY--EDLVRMMGE 396
            R L+++LV ++ L+L+    +     F +K I  I    +L    Y +  E+L+    +
Sbjct: 109 WRALKQQLVNKFTLRLVSCVQLASKLSFRNKIISNITVLNFLQALGYLHTKEELLESELD 168

Query: 397 IVSALEGKIRVPTVVDYKEVLL-------TLVPVELRTQHLCSFLCEL----------SL 439
           ++ +L  +I +PT + Y E LL        LVP  +R    C  L +L          SL
Sbjct: 169 VLKSLNFRINLPTPLAYVETLLEVLGYNGCLVPA-MRLHATCLTLLDLVYLLHEPIYESL 227

Query: 440 LHTSLSAYAPARL 452
           L  S+    P++L
Sbjct: 228 LRASIENSTPSQL 240


>gi|5031767 heat shock transcription factor 1 [Homo sapiens]
          Length = 529

 Score = 36.2 bits (82), Expect = 0.12
 Identities = 39/128 (30%), Positives = 56/128 (43%), Gaps = 25/128 (19%)

Query: 662 DKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTA-SPTSSVDGGLG- 719
           D+ P     L    + P +P   P V  +  PG+       SSV T  SPT+ +D  L  
Sbjct: 285 DERPLSSSPLVRVKEEPPSPPQSPRVEEA-SPGRP------SSVDTLLSPTALIDSILRE 337

Query: 720 ALPQPTSVLSL-DSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQQVK-----RINLCIH 773
           + P P SV +L D+  HT            + RPPSPP +S P++ +      +  L  H
Sbjct: 338 SEPAPASVTALTDARGHTDT----------EGRPPSPPPTSTPEKCLSVACLDKNELSDH 387

Query: 774 SEEEDMNL 781
            +  D NL
Sbjct: 388 LDAMDSNL 395


>gi|5031703 Ras-GTPase-activating protein SH3-domain-binding protein
           [Homo sapiens]
          Length = 466

 Score = 35.8 bits (81), Expect = 0.16
 Identities = 48/199 (24%), Positives = 75/199 (37%), Gaps = 52/199 (26%)

Query: 583 GSFVTTPTAELSSQEETLLGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDVTVVY 642
           G FVT P  E  S+EE                 E  +E +   E          D  VV 
Sbjct: 139 GGFVTEPQEE--SEEEV----------------EEPEERQQTPEVVPDDSGTFYDQAVVS 180

Query: 643 LNPEQHCCQESSDEEACPEDKGPQDP--------------QALALDTQIPATPGPKPLVR 688
            + E+H  +  ++ E  PE +  Q+P              +    D Q  ++P P  + +
Sbjct: 181 NDMEEHLEEPVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADIAQ 240

Query: 689 TSREPGKDVTTSGYSSVSTASPTSSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCL 748
           T +E   D+ T  ++SV++ +   S     GA+P             T    H  +    
Sbjct: 241 TVQE---DLRTFSWASVTSKNLPPS-----GAVPV------------TGIPPHVVKVPAS 280

Query: 749 QCRPPSPPESSVPQQQVKR 767
           Q RP S PES +P Q+ +R
Sbjct: 281 QPRPESKPESQIPPQRPQR 299


>gi|38327552 Ras-GTPase-activating protein SH3-domain-binding
           protein [Homo sapiens]
          Length = 466

 Score = 35.8 bits (81), Expect = 0.16
 Identities = 48/199 (24%), Positives = 75/199 (37%), Gaps = 52/199 (26%)

Query: 583 GSFVTTPTAELSSQEETLLGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDVTVVY 642
           G FVT P  E  S+EE                 E  +E +   E          D  VV 
Sbjct: 139 GGFVTEPQEE--SEEEV----------------EEPEERQQTPEVVPDDSGTFYDQAVVS 180

Query: 643 LNPEQHCCQESSDEEACPEDKGPQDP--------------QALALDTQIPATPGPKPLVR 688
            + E+H  +  ++ E  PE +  Q+P              +    D Q  ++P P  + +
Sbjct: 181 NDMEEHLEEPVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADIAQ 240

Query: 689 TSREPGKDVTTSGYSSVSTASPTSSVDGGLGALPQPTSVLSLDSDSHTQPCHHQARKSCL 748
           T +E   D+ T  ++SV++ +   S     GA+P             T    H  +    
Sbjct: 241 TVQE---DLRTFSWASVTSKNLPPS-----GAVPV------------TGIPPHVVKVPAS 280

Query: 749 QCRPPSPPESSVPQQQVKR 767
           Q RP S PES +P Q+ +R
Sbjct: 281 QPRPESKPESQIPPQRPQR 299


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,236,477
Number of Sequences: 37866
Number of extensions: 1526431
Number of successful extensions: 5672
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 89
Number of HSP's that attempted gapping in prelim test: 5532
Number of HSP's gapped (non-prelim): 310
length of query: 786
length of database: 18,247,518
effective HSP length: 110
effective length of query: 676
effective length of database: 14,082,258
effective search space: 9519606408
effective search space used: 9519606408
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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