Guide to the Human Genome
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Search of human proteins with 118150654

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118150654 non-protein coding RNA 153 isoform 1 [Homo
sapiens]
         (673 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118150654 non-protein coding RNA 153 isoform 1 [Homo sapiens]     1341   0.0  
gi|247301318 non-protein coding RNA 153 isoform 2 [Homo sapiens]     1133   0.0  
gi|247301334 non-protein coding RNA 153 isoform 3 [Homo sapiens]     1074   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    49   2e-05
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         45   2e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     44   4e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    43   8e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    43   8e-04
gi|54633319 PDZ domain-containing guanine nucleotide exchange fa...    43   0.001
gi|221219020 NYD-SP11 protein [Homo sapiens]                           42   0.002
gi|58331189 T-cell lymphoma invasion and metastasis 2 isoform b ...    42   0.002
gi|58331187 T-cell lymphoma invasion and metastasis 2 isoform a ...    42   0.002
gi|20336260 retinoblastoma protein-binding zinc finger protein i...    41   0.003
gi|20336258 retinoblastoma protein-binding zinc finger protein i...    41   0.003
gi|148806891 hypothetical protein LOC54906 [Homo sapiens]              40   0.007
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         40   0.009
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         40   0.009
gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]         39   0.012
gi|54633315 deoxynucleotidyltransferase, terminal, interacting p...    39   0.016
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    39   0.016
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             39   0.016
gi|224586823 coiled-coil domain containing 110 isoform b [Homo s...    39   0.016
gi|22749515 coiled-coil domain containing 110 isoform a [Homo sa...    39   0.016
gi|34996489 pleckstrin homology domain interacting protein [Homo...    39   0.020
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          39   0.020
gi|124249396 coiled-coil domain containing 30 [Homo sapiens]           38   0.035
gi|4505257 moesin [Homo sapiens]                                       38   0.035
gi|21396500 HIRA interacting protein 3 [Homo sapiens]                  38   0.035
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    37   0.045
gi|190194423 SPARC-like 1 [Homo sapiens]                               37   0.045

>gi|118150654 non-protein coding RNA 153 isoform 1 [Homo sapiens]
          Length = 673

 Score = 1341 bits (3471), Expect = 0.0
 Identities = 673/673 (100%), Positives = 673/673 (100%)

Query: 1   MSRTLASAVPLSSPDYYERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLK 60
           MSRTLASAVPLSSPDYYERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLK
Sbjct: 1   MSRTLASAVPLSSPDYYERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLK 60

Query: 61  NYLKEICESEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKD 120
           NYLKEICESEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKD
Sbjct: 61  NYLKEICESEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKD 120

Query: 121 SLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSP 180
           SLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSP
Sbjct: 121 SLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSP 180

Query: 181 QPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTA 240
           QPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTA
Sbjct: 181 QPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTA 240

Query: 241 SVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSE 300
           SVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSE
Sbjct: 241 SVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSE 300

Query: 301 GEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKP 360
           GEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKP
Sbjct: 301 GEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKP 360

Query: 361 FRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQER 420
           FRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQER
Sbjct: 361 FRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQER 420

Query: 421 VALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVK 480
           VALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVK
Sbjct: 421 VALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVK 480

Query: 481 EEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVS 540
           EEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVS
Sbjct: 481 EEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVS 540

Query: 541 SGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGS 600
           SGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGS
Sbjct: 541 SGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGS 600

Query: 601 GAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRP 660
           GAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRP
Sbjct: 601 GAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRP 660

Query: 661 RNHNTDDSDDFYD 673
           RNHNTDDSDDFYD
Sbjct: 661 RNHNTDDSDDFYD 673


>gi|247301318 non-protein coding RNA 153 isoform 2 [Homo sapiens]
          Length = 570

 Score = 1133 bits (2931), Expect = 0.0
 Identities = 568/570 (99%), Positives = 570/570 (100%)

Query: 104 LKLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQ 163
           ++LEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQ
Sbjct: 1   MQLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQ 60

Query: 164 MSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDN 223
           MSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDN
Sbjct: 61  MSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDN 120

Query: 224 IDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLS 283
           IDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLS
Sbjct: 121 IDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLS 180

Query: 284 PENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPW 343
           PENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPW
Sbjct: 181 PENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPW 240

Query: 344 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 403
           EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME
Sbjct: 241 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 300

Query: 404 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 463
           GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA
Sbjct: 301 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 360

Query: 464 QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEA 523
           QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEA
Sbjct: 361 QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEA 420

Query: 524 KPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRF 583
           KPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRF
Sbjct: 421 KPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRF 480

Query: 584 QKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNAL 643
           QKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNAL
Sbjct: 481 QKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNAL 540

Query: 644 WDESDDSNSEIEAALRPRNHNTDDSDDFYD 673
           WDESDDSNSEIEAALRPRNHNTDDSDDFYD
Sbjct: 541 WDESDDSNSEIEAALRPRNHNTDDSDDFYD 570


>gi|247301334 non-protein coding RNA 153 isoform 3 [Homo sapiens]
          Length = 540

 Score = 1074 bits (2777), Expect = 0.0
 Identities = 538/539 (99%), Positives = 539/539 (100%)

Query: 135 KVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH 194
           +VAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH
Sbjct: 2   QVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSH 61

Query: 195 RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI 254
           RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI
Sbjct: 62  RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEI 121

Query: 255 GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK 314
           GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK
Sbjct: 122 GSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEK 181

Query: 315 RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST 374
           RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST
Sbjct: 182 RASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWST 241

Query: 375 SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL 434
           SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL
Sbjct: 242 SSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTL 301

Query: 435 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 494
           SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE
Sbjct: 302 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 361

Query: 495 CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA 554
           CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA
Sbjct: 362 CGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAA 421

Query: 555 DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE 614
           DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE
Sbjct: 422 DIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASE 481

Query: 615 ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD 673
           ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD
Sbjct: 482 ASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD 540


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 91/505 (18%), Positives = 178/505 (35%), Gaps = 39/505 (7%)

Query: 172  DFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQ 231
            D S  + S     + S     S   ++ SSN +DS     S+D+   + SD+ D K+   
Sbjct: 570  DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS--DSSDSSDSKSDSS 627

Query: 232  IGEKMPVTASVLSEEEQTHCLEIGSNT-RHGKSNLSEGKKSAELNSPLRERLSPENRTTD 290
              E     +   S+   ++  +   N+     SN S    S++ +       S ++  + 
Sbjct: 628  KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687

Query: 291  LKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHL 350
               DSS  S             E   S   S    S+  +S N  S +  S     S   
Sbjct: 688  DSSDSSDSSNS----------SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737

Query: 351  AHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEA 410
            ++    S         +  +S  +S+    S S D           +        D  ++
Sbjct: 738  SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797

Query: 411  LKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVA 470
                 +     +  +  +    + +S DS   S ++  +     +  SD   +  G    
Sbjct: 798  SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD---SSDGSDSD 854

Query: 471  TLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLN 530
            +    D+S   +++     + + +    S   S+ESS S  S  + NS   ++      +
Sbjct: 855  SSNRSDSSNSSDSSDSSDSSNSSDSSDSS--DSNESSNSSDSSDSSNSSDSDSS-----D 907

Query: 531  SVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASV 590
            S  + +   SS   D S+  N +                +   D++N +++      ++ 
Sbjct: 908  SSNSSDSSDSSNSSDSSESSNSS--------------DNSNSSDSSNSSDSSDSSDSSNS 953

Query: 591  SHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESD-- 648
            S  S  +  S + ++  +N   S  S +SS+ S  S   +      +  S+   D SD  
Sbjct: 954  SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013

Query: 649  DSNSEIEAALRPRNHNTDDSDDFYD 673
            DS++  +++    + N+ DS D  D
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSD 1038



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 89/505 (17%), Positives = 176/505 (34%), Gaps = 18/505 (3%)

Query: 172  DFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQ 231
            D S    S     + +  D      ++ SSN +DS     S+D+   N SD+ +   S  
Sbjct: 775  DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834

Query: 232  IGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDL 291
                   + S  S +      +  S+ R   SN S+   S++ ++      S ++  +  
Sbjct: 835  SSNSSDSSDSSDSSDGS----DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890

Query: 292  KCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLA 351
              DSS  S     + +    +   +S        S+  ES N       S     SD   
Sbjct: 891  SSDSSDSSN----SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD--- 943

Query: 352  HREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEAL 411
                 S               S SSD + S S D     +     +     +  D  ++ 
Sbjct: 944  --SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001

Query: 412  KLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVAT 471
                +     +  +  +      S   +  +SS ++ + +   + DS           ++
Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061

Query: 472  LKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSI-LNDNSGIKEAKPAVWLN 530
                 +   + + +      +E      + +SS+SS S  S   +D+S   ++  +   +
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS--SD 1119

Query: 531  SVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASV 590
            S  + +   SS   D S   N +     +E+        ++   +++ + +    +D+S 
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1179

Query: 591  SHLSGLNIGSGAFETKTANKIASEASFS--SSEGSPLSRHENKKKPVINLKSNALWDESD 648
            S  S  +  S      + +  +S++S S  SS+ S  S   +      +  SN   D SD
Sbjct: 1180 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239

Query: 649  DSNSEIEAALRPRNHNTDDSDDFYD 673
             S+S   +     + ++D SD   D
Sbjct: 1240 SSDSSDSSNSSDSSDSSDSSDSTSD 1264



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 83/500 (16%), Positives = 182/500 (36%), Gaps = 26/500 (5%)

Query: 174  STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQ----CLNKSDNIDGKAS 229
            S++  S   + N    D  +   ++ SS+ +DS    +S+D+       + SD+ +   S
Sbjct: 642  SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701

Query: 230  LQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTT 289
                +     +S  S+   ++  +  S+     S+ S    S++ +       S ++  +
Sbjct: 702  SDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 761

Query: 290  DLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDH 349
                DSS  S+    +      +   +S        S+  +S N       S     SD 
Sbjct: 762  SNSSDSSDSSDSSDSS------DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815

Query: 350  LAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIE 409
                   S          +  + S SSD + S    D    +     N     +  D   
Sbjct: 816  SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875

Query: 410  ALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHV 469
            +     +     + ++  +    + +S DS+   S+N+       +  SD   +      
Sbjct: 876  SSDSSDSSDSNESSNSSDSS--DSSNSSDSDSSDSSNS-------SDSSDSSNSSDSSES 926

Query: 470  ATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWL 529
            +   ++ NS  + + +      ++      + +SS+SS S  S  +++S   ++      
Sbjct: 927  SNSSDNSNS-SDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS----- 980

Query: 530  NSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDAS 589
            NS  + +   SS   D S   N +     +++        ++   +++ + +    +D+S
Sbjct: 981  NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040

Query: 590  VSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDD 649
             S  S  +  S      + +  +S++S  SS+ S  S   +  +   +  S+   D SD 
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSS-DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099

Query: 650  SNSEIEAALRPRNHNTDDSD 669
            S+S   +     + ++D SD
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSD 1119



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 85/496 (17%), Positives = 174/496 (35%), Gaps = 22/496 (4%)

Query: 174  STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIG 233
            S++      + + S     S  ++  S + +DS    + +D+   N SD+ D   S    
Sbjct: 601  SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660

Query: 234  EKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKC 293
                 + S  S +         S+     S+ S+   S+E +       S  + ++D   
Sbjct: 661  NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720

Query: 294  DSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHR 353
             +SS S+    +          +S        S+  +S +  +    S     SD  +  
Sbjct: 721  SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD--SSD 778

Query: 354  EPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKL 413
               S          +    S SSD + S    D    S     N        D  ++   
Sbjct: 779  SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDS--- 835

Query: 414  IHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLK 473
             ++     +  +       + +  DS   S ++  +     +  SD   +    + +   
Sbjct: 836  SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895

Query: 474  EHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVP 533
            +  NS   +++     + + +    S   SSESS S     +DNS   ++      NS  
Sbjct: 896  DSSNSSDSDSSDSSNSSDSSDSSNSS--DSSESSNS-----SDNSNSSDSS-----NSSD 943

Query: 534  TREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHL 593
            + +   SS   D S   + +     +++ +      +   D+++ +++    +D+S S  
Sbjct: 944  SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS----SDSSDSSD 999

Query: 594  SGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSE 653
            S  N    +  + +++   S  S +SS+ S  S   +      +  S+   D SD SNS 
Sbjct: 1000 SS-NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058

Query: 654  IEAALRPRNHNTDDSD 669
              +     + ++D SD
Sbjct: 1059 DSSDSSDSSDSSDSSD 1074



 Score = 38.9 bits (89), Expect = 0.016
 Identities = 88/504 (17%), Positives = 179/504 (35%), Gaps = 17/504 (3%)

Query: 174  STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIG 233
            S++  +   + N S     S    + SSN +DS     S+D+   N SD+ D   S    
Sbjct: 794  SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS--NSSDSSDSSDSSDGS 851

Query: 234  EKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLK- 292
            +      S  S    +      SN+    S+ S+  +S+  +       S ++ ++D   
Sbjct: 852  DSDSSNRSDSSNSSDSSDSSDSSNSSDS-SDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910

Query: 293  -CDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLA 351
              DSS  S     +      +   +S   +    S+  +S N       S     SD   
Sbjct: 911  SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970

Query: 352  HREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEAL 411
                 S          +    S SSD + S +  D    S +   +       +    + 
Sbjct: 971  SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD----SSDSSDSSDSSNSSDSSNSSD 1026

Query: 412  KLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVAT 471
                ++    + S++ +    +  S DS   S ++  +     +  SD   +      + 
Sbjct: 1027 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1086

Query: 472  LKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNS 531
              +  NS     ++    +        S+  S  S+ S  S  +D+S   ++  +   +S
Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS--DS 1144

Query: 532  VPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVS 591
              + E   SS   D S   + +     +++        ++   +++ + +    +D+S S
Sbjct: 1145 SDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204

Query: 592  HLSGLNIGSGAFETKTANKIASEASFS-----SSEGSPLSRHENKKKPVINL-KSNALWD 645
              S  +  S      + +  +S++S S     SS+ S  S   N      +   S++  D
Sbjct: 1205 SDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSD 1264

Query: 646  ESDDSNSEIEAALRPRNHNTDDSD 669
             +D+S+S+ ++     N +  DSD
Sbjct: 1265 SNDESDSQSKSGNGNNNGSDSDSD 1288


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 80/370 (21%), Positives = 143/370 (38%), Gaps = 38/370 (10%)

Query: 300 EGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQK 359
           EG++  RE  E+EE       + + + E  E E K     HS  E               
Sbjct: 309 EGKVAQREE-ELEE--TGNQHNDVEIEEAGEEEEKEIAIVHSDAE--------------- 350

Query: 360 PFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPN-PGGKMEGEDGIEALKLIHAEQ 418
              K QEEEE+      ++ + + E+  + ES + Q + P   M+  + +E +K + A+Q
Sbjct: 351 ---KEQEEEEQK----QEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQ 403

Query: 419 ERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVG-QHVATLK-EHD 476
           E +  +  ++        P   + S    P  E    PD +      G ++V+ L  E +
Sbjct: 404 EVMETNRVESV------EPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKE 457

Query: 477 NSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTRE 536
           +  KEE  +  +     +   +S       S S P + +      E      L   P   
Sbjct: 458 SEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVT 517

Query: 537 QEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGL 596
           QE   G     +K+     + +TE     +L      ++ ++T+ R +    + +  S  
Sbjct: 518 QE--QGHLLPERKDFPVESVKLTEVPVEPVL--TVHPESKSKTKTRSRSRGRARNKTSKS 573

Query: 597 NIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEA 656
              S +  + +++  +S +  SSS GS  SR  +      +  S+     S  S+SE  +
Sbjct: 574 RSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRS 633

Query: 657 ALRPRNHNTD 666
             R R HN D
Sbjct: 634 RSRGRGHNRD 643


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 65/289 (22%), Positives = 117/289 (40%), Gaps = 44/289 (15%)

Query: 225 DGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERL-- 282
           + K+ ++   K P  A    +EE     E+ S  +       E K   E  SP +E    
Sbjct: 515 EAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKS 574

Query: 283 -----SPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQ 337
                SPE   +  K ++ S +E +   +    V+E+  SP  +  PV E    E K   
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE----EAKSPA 630

Query: 338 EKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPN 397
           E  SP +  S      + +++ P +    E+EE+                  +SPE   +
Sbjct: 631 EVKSPEKAKSP----TKEEAKSPEKAKSPEKEEA------------------KSPEKAKS 668

Query: 398 PGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPD 457
           P  K E +   +A   + AE +  +    K+ + +   SP+  K     +P +E  ++P+
Sbjct: 669 P-VKAEAKSPEKAKSPVKAEAK--SPEKAKSPVKEEAKSPEKAK-----SPVKEEAKSPE 720

Query: 458 SDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSES 506
               ++ V +   T ++  + VKEEA +   KA + E  +   + S E+
Sbjct: 721 K--AKSPVKEEAKTPEKAKSPVKEEAKS-PEKAKSPEKAKTLDVKSPEA 766



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 59/274 (21%), Positives = 110/274 (40%), Gaps = 29/274 (10%)

Query: 234 EKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRT-TDLK 292
           E+  VT  V  EEE+    E G     G+   +EG +    + P  E  SPE    + +K
Sbjct: 462 EETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVK 521

Query: 293 CDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYC----ESENKWSQEKHSPWEGVSD 348
            ++ S +E +   +E  +   +  SP  +  P  E      E+++   +E  SP E  S 
Sbjct: 522 EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSP 581

Query: 349 HLAH----------REPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNP 398
             A            E KS +  +   +EE +S + +       ++    ++SPE   +P
Sbjct: 582 EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP 641

Query: 399 GGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKE---------SSTNAPT 449
             K E +   +A      ++E  +    K+ +     SP+  K              +P 
Sbjct: 642 -TKEEAKSPEKAKS--PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698

Query: 450 REPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEA 483
           +E  ++P+    ++ V +   + ++  + VKEEA
Sbjct: 699 KEEAKSPEK--AKSPVKEEAKSPEKAKSPVKEEA 730



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 60/286 (20%), Positives = 110/286 (38%), Gaps = 27/286 (9%)

Query: 235 KMPVTASVLSEEE-QTHCLEIGSNTRHGKSNLSEGKKSAE-LNSPLRERL-------SPE 285
           K PV     S E+ ++   E   +    KS + E  K+ E   SP++E         SPE
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754

Query: 286 N-RTTDLKC--------DSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWS 336
             +T D+K         + +     +   +    V+E+  SP  +  P+ E  ++  K  
Sbjct: 755 KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEI 814

Query: 337 QEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEP-- 394
            +K      V +    +E K ++P +K +EE+  +   + +   S  E+    E+P+P  
Sbjct: 815 PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKV 874

Query: 395 --QPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREP 452
             +  P  +   E  +EA K   AE ++   + EK    +     D++ +  T    +EP
Sbjct: 875 EEKKEPAVEKPKESKVEA-KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP 933

Query: 453 ----GQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEE 494
                + P     + +        KE      EE      KA  ++
Sbjct: 934 DDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979



 Score = 33.1 bits (74), Expect = 0.86
 Identities = 40/199 (20%), Positives = 76/199 (38%), Gaps = 6/199 (3%)

Query: 346 VSDHLAHREPKSQKPFRKMQEE----EEESWSTSSDLTISISEDDLILESPEPQPNPGGK 401
           VS H+  +  +  K   K ++E    EE++  T     ++  E+    E    +   G +
Sbjct: 432 VSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEE 491

Query: 402 MEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVP 461
            E E G E  K   AE+        K+ + +   SP +E +S      + P +    +  
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP-AEAKSPEKEEAKSPAEVKSPEKA 550

Query: 462 RAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIK 521
           ++   +   +  E  +  KEEA +   +  + E  +  A   ++S     S     S +K
Sbjct: 551 KSPAKEEAKSPPEAKSPEKEEAKS-PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609

Query: 522 EAKPAVWLNSVPTREQEVS 540
           E   +      P +E+  S
Sbjct: 610 EEAKSPAEAKSPVKEEAKS 628


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 23/278 (8%)

Query: 330 ESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLIL 389
           E+E +    K SP +  +  +   E + ++   + +EEEE+  + S       SE +   
Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 559

Query: 390 ESPEPQPNPG---GKMEGEDGIEALKLIHAEQERVALSTEKNCILQT-LSSPDSEKESST 445
           E  E +   G    + EGE+  EA +    E++   ++T++  +    +  P+  K    
Sbjct: 560 EKEEGEQEEGETEAEAEGEEA-EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 618

Query: 446 NAPTREPGQTPDSDVPRAQVGQH---VATLKEHDNS------VKEEATALLRKALTEECG 496
            +P  E G++P    P  + G+     + ++E   S      V+E+  + + K+  EE  
Sbjct: 619 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 678

Query: 497 R----RSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKS----- 547
           +    +S +  ++S   +          KE K A     V  +E++       K      
Sbjct: 679 KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 738

Query: 548 KKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQK 585
           K+E VA  + IT++    L K+   +    Q E   +K
Sbjct: 739 KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEK 776


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 23/278 (8%)

Query: 330 ESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLIL 389
           E+E +    K SP +  +  +   E + ++   + +EEEE+  + S       SE +   
Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSS 183

Query: 390 ESPEPQPNPG---GKMEGEDGIEALKLIHAEQERVALSTEKNCILQT-LSSPDSEKESST 445
           E  E +   G    + EGE+  EA +    E++   ++T++  +    +  P+  K    
Sbjct: 184 EKEEGEQEEGETEAEAEGEEA-EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 242

Query: 446 NAPTREPGQTPDSDVPRAQVGQH---VATLKEHDNS------VKEEATALLRKALTEECG 496
            +P  E G++P    P  + G+     + ++E   S      V+E+  + + K+  EE  
Sbjct: 243 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 302

Query: 497 R----RSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKS----- 547
           +    +S +  ++S   +          KE K A     V  +E++       K      
Sbjct: 303 KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 362

Query: 548 KKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQK 585
           K+E VA  + IT++    L K+   +    Q E   +K
Sbjct: 363 KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEK 400


>gi|54633319 PDZ domain-containing guanine nucleotide exchange factor
            I [Homo sapiens]
          Length = 1601

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 75/342 (21%), Positives = 132/342 (38%), Gaps = 49/342 (14%)

Query: 174  STEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQ-- 231
            S+ H SP  +   S    ++   +A+S N++DS   + S+ +  ++        A+LQ  
Sbjct: 1232 SSLHSSPPASPQGSPHKGYTLIPSAKSDNLSDSSHSEISSRSSIVSNCSVDSMSAALQDE 1291

Query: 232  --IGEKMPVTASVLSEEEQTHCLEIGSNTRHGKS----NLSEGKKSAELNSPLRERLSPE 285
                + + V  S  + E+  H   IG +++HG        S  K  A  +S   E +S E
Sbjct: 1292 RCSSQALAVPESTGALEKTEHASGIGDHSQHGPGWTLLKPSLIKCLAVSSSVSNEEISQE 1351

Query: 286  NRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEG 345
            +   +   DS  GS     +  H   +         P P S        W          
Sbjct: 1352 HIIIEA-ADSGRGSWTSCSSSSHDNFQSL-------PNPKS--------WDFLNSYRHTH 1395

Query: 346  VSDHLAHREPKSQKPFRKMQE-----------EEEESWSTSSDLTISISEDDLILESPEP 394
            + D +A  EP   +P+   +             E +SW++SS L+ +   +   ++    
Sbjct: 1396 LDDPIAEVEPTDSEPYSCSKSCSRTCGQCKGSLERKSWTSSSSLSDTYEPNYGTVKRRVL 1455

Query: 395  QPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQ 454
            +  P    EG D  +A   ++   + V  STEK  I+  ++SP  +         REP  
Sbjct: 1456 ESTPAESSEGLDPKDATDPVY---KTVTSSTEKGLIVYCVTSPKKDDR------YREPPP 1506

Query: 455  TPDS----DVPRAQVGQHVATLKEHDNSVKEEATALLRKALT 492
            TP       +   + G H   LK  D SV  + + ++  +L+
Sbjct: 1507 TPPGYLGISLADLKEGPH-THLKPPDYSVAVQRSKMMHNSLS 1547


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 118/586 (20%), Positives = 215/586 (36%), Gaps = 57/586 (9%)

Query: 31   EKKRLDLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRNQEYLKRFERVQAH 90
            +KK L  EKK     +    + K   +    Y KE     KK   + +  L  F ++ A 
Sbjct: 1835 QKKNLAQEKKNLAQEKEKLAQRKENLL----YNKERLTHSKKQLVQVKNKLGMFNKILAQ 1890

Query: 91   VVH-FTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMS 149
            V    T   E + K K +     KK++  +DSL  K+E   +++ K+A+ + +  G    
Sbjct: 1891 VEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRL 1950

Query: 150  RGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVV 209
            RG    A      + +  L M+  + E       K     +  S  +T ++S        
Sbjct: 1951 RGELDIAK----EEKALNLEMKRLAEEKMRLVEGK-----ETLSKGETPETSRQRK---- 1997

Query: 210  QTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGK 269
             T  + +   +  +++ K  L     + +  S +++ +    LE    TR  +  +   +
Sbjct: 1998 MTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGK----LEF---TRGQRIFVQGQR 2050

Query: 270  KSAELNSPL---RERLS--PENRTTDLKCDSSSGSEGEILTREHIE---------VEEKR 315
            K A+ +  L   RE LS  P      LK       +   LT+E I+         V+E+R
Sbjct: 2051 KLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERR 2110

Query: 316  ASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTS 375
             S   S + + E+  S      EK S        LA ++ K     R+M  +EE+     
Sbjct: 2111 LSIEQSKLDIKEWDFS------EKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEE 2164

Query: 376  SDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLS 435
            S L    SE  +IL+  E      G +E E+ I  LK    +++      +     +  S
Sbjct: 2165 SKLARKHSE--VILDDEEE-----GGIEEEEVIPFLKRRWRKRKEAKRGDKPK---EKFS 2214

Query: 436  SPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEEC 495
            S   E ES  +          + +   +   +     +E +   +EE      +   EE 
Sbjct: 2215 SQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEE 2274

Query: 496  GRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAAD 555
            G    +   E              ++E +           E+E  S   ++ ++E+ + +
Sbjct: 2275 GEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE 2334

Query: 556  IPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSG 601
              +   +  ++LKK        Q     +  +  +S L G+  G G
Sbjct: 2335 EEVDREK--EILKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKG 2378


>gi|58331189 T-cell lymphoma invasion and metastasis 2 isoform b
           [Homo sapiens]
          Length = 626

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 94/430 (21%), Positives = 173/430 (40%), Gaps = 53/430 (12%)

Query: 54  LKYVKLKNYLKEICESEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIK 113
           LKY  L   L  + + E + H    E LK  E+V +H+        ++QK+  +Y T   
Sbjct: 178 LKYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHI-------NEMQKIYEDYGTVFD 230

Query: 114 KMLCSKDSLGLKEELTDEDREKVAVHEGIN-SGTAMSRGLYQ---PATIFMGRQMSAILS 169
           +++  +   G ++E+T+    ++ +H  ++     +S G  +     T+F+ ++   ++ 
Sbjct: 231 QLVAEQS--GTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDLELTVFVFKRAVILVY 288

Query: 170 MRDFSTEHKSP---QPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKS--DNI 224
             +   + K P   +P  N +  DP   R     S    +  V+  N     N S  + I
Sbjct: 289 KENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPIS----ALQVRLGNPAGTENNSIWELI 344

Query: 225 DGKASLQIGEKMPVTASVLSEEEQTHCLEI------GSNTRHGKSNLSEGKKSAELNSPL 278
             K+ ++   +          E +T+ +++       +  RH K  L   K   +   PL
Sbjct: 345 HTKSEIEGRPETIFQLCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPL 404

Query: 279 RER------LSPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPV--SPIPVSEYCE 330
           + R      L+       LK  SS+   GE      ++ +E   S     S  P +E  +
Sbjct: 405 KNRVPVSAKLASSRSLKVLKNSSSNEWTGETGKGTLLDSDEGSLSSGTQSSGCPTAEGRQ 464

Query: 331 SENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEE--ESWSTSSDLTIS-----IS 383
                S  K+ P  G++D   +   +S     +  +  +  +  S + D+ I      IS
Sbjct: 465 DSKSTSPGKY-PHPGLADFADNLIKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRIS 523

Query: 384 EDDLILESPEPQPNPGGKMEGEDGIEALKLIHAE---QERVALST--EKNCILQTL---S 435
           ED  +    E QP P    EG+ G E  KL+       +R A ST  ++  +L+      
Sbjct: 524 EDPDVHPEAEQQPGPESG-EGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIRHQ 582

Query: 436 SPDSEKESST 445
           S DS+ E++T
Sbjct: 583 SLDSQSENAT 592


>gi|58331187 T-cell lymphoma invasion and metastasis 2 isoform a [Homo
            sapiens]
          Length = 1701

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 94/430 (21%), Positives = 173/430 (40%), Gaps = 53/430 (12%)

Query: 54   LKYVKLKNYLKEICESEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIK 113
            LKY  L   L  + + E + H    E LK  E+V +H+        ++QK+  +Y T   
Sbjct: 1253 LKYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHI-------NEMQKIYEDYGTVFD 1305

Query: 114  KMLCSKDSLGLKEELTDEDREKVAVHEGIN-SGTAMSRGLYQ---PATIFMGRQMSAILS 169
            +++  +   G ++E+T+    ++ +H  ++     +S G  +     T+F+ ++   ++ 
Sbjct: 1306 QLVAEQS--GTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDLELTVFVFKRAVILVY 1363

Query: 170  MRDFSTEHKSP---QPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKS--DNI 224
              +   + K P   +P  N +  DP   R     S    +  V+  N     N S  + I
Sbjct: 1364 KENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPIS----ALQVRLGNPAGTENNSIWELI 1419

Query: 225  DGKASLQIGEKMPVTASVLSEEEQTHCLEI------GSNTRHGKSNLSEGKKSAELNSPL 278
              K+ ++   +          E +T+ +++       +  RH K  L   K   +   PL
Sbjct: 1420 HTKSEIEGRPETIFQLCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPL 1479

Query: 279  RER------LSPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPV--SPIPVSEYCE 330
            + R      L+       LK  SS+   GE      ++ +E   S     S  P +E  +
Sbjct: 1480 KNRVPVSAKLASSRSLKVLKNSSSNEWTGETGKGTLLDSDEGSLSSGTQSSGCPTAEGRQ 1539

Query: 331  SENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEE--ESWSTSSDLTIS-----IS 383
                 S  K+ P  G++D   +   +S     +  +  +  +  S + D+ I      IS
Sbjct: 1540 DSKSTSPGKY-PHPGLADFADNLIKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRIS 1598

Query: 384  EDDLILESPEPQPNPGGKMEGEDGIEALKLIHAE---QERVALST--EKNCILQTL---S 435
            ED  +    E QP P    EG+ G E  KL+       +R A ST  ++  +L+      
Sbjct: 1599 EDPDVHPEAEQQPGPESG-EGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIRHQ 1657

Query: 436  SPDSEKESST 445
            S DS+ E++T
Sbjct: 1658 SLDSQSENAT 1667


>gi|20336260 retinoblastoma protein-binding zinc finger protein
           isoform b [Homo sapiens]
          Length = 1682

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 56/225 (24%), Positives = 84/225 (37%), Gaps = 34/225 (15%)

Query: 344 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 403
           E  S       PKS+K  +K QE + +  +   D+ +  SE D    S   + +  G  E
Sbjct: 155 ERASARSKRSSPKSRKGKKKSQENKNKG-NKIQDIQLKTSEPDFT--SANMRDSAEGPKE 211

Query: 404 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 463
            E+   A  L            E+   LQ ++S +   E +T AP  EP   PD  +  A
Sbjct: 212 DEEKPSASAL------------EQPATLQEVASQEVPPELATPAPAWEPQPEPDERLEAA 259

Query: 464 -----QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNS 518
                 +G+     +E D   +E+          E+ G   A   +E+S   P I  D  
Sbjct: 260 ACEVNDLGEEEEEEEEEDEEEEEDDD----DDELEDEGEEEASMPNENSVKEPEIRCDE- 314

Query: 519 GIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEA 563
                KP   L    T  +E    C + +     A  IP T+ EA
Sbjct: 315 -----KPEDLLEEPKTTSEETLEDCSEVTP----AMQIPRTKEEA 350


>gi|20336258 retinoblastoma protein-binding zinc finger protein
           isoform a [Homo sapiens]
          Length = 1718

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 56/225 (24%), Positives = 84/225 (37%), Gaps = 34/225 (15%)

Query: 344 EGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKME 403
           E  S       PKS+K  +K QE + +  +   D+ +  SE D    S   + +  G  E
Sbjct: 155 ERASARSKRSSPKSRKGKKKSQENKNKG-NKIQDIQLKTSEPDFT--SANMRDSAEGPKE 211

Query: 404 GEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRA 463
            E+   A  L            E+   LQ ++S +   E +T AP  EP   PD  +  A
Sbjct: 212 DEEKPSASAL------------EQPATLQEVASQEVPPELATPAPAWEPQPEPDERLEAA 259

Query: 464 -----QVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNS 518
                 +G+     +E D   +E+          E+ G   A   +E+S   P I  D  
Sbjct: 260 ACEVNDLGEEEEEEEEEDEEEEEDDD----DDELEDEGEEEASMPNENSVKEPEIRCDE- 314

Query: 519 GIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEA 563
                KP   L    T  +E    C + +     A  IP T+ EA
Sbjct: 315 -----KPEDLLEEPKTTSEETLEDCSEVTP----AMQIPRTKEEA 350


>gi|148806891 hypothetical protein LOC54906 [Homo sapiens]
          Length = 2430

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)

Query: 282 LSPENRTT---DLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSE----YCESE-- 332
           + PEN T    DL  +S    + + L      + +   S   S  PVSE    +C SE  
Sbjct: 509 VQPENTTAAHNDLPENSIVNYDSQALNM----LADLALSSATSSTPVSEARNLHCSSELP 564

Query: 333 -NKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILES 391
            N     K +   G SDH  HR  K+QK         +   ++ SDLT+S  E+ L+  S
Sbjct: 565 QNDVLLSKENSLRGTSDHEYHRGVKTQKGELLPNPSSDRKSNSGSDLTVSQDEESLVPCS 624

Query: 392 PEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAP--T 449
             P        E     E L+   A Q           +L T  S    +E    +P   
Sbjct: 625 QAPAKAQSALTE-----EMLESSDASQSSSVSVEHSYALLLTEHSKKHLQEREILSPLFP 679

Query: 450 REPGQTPDSDVPRAQV 465
           R   ++P++  P  +V
Sbjct: 680 RNGTKSPEAATPVGKV 695


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 64/353 (18%), Positives = 136/353 (38%), Gaps = 31/353 (8%)

Query: 55   KYVKLKNYLKEICESEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKK 114
            K + ++   K I ES++K   R+Q   K  E+++          EK +K+K E++++   
Sbjct: 781  KEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTF------EKEKKIKHEHKSE--- 831

Query: 115  MLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFS 174
                KD L L E   D+ +EK  ++   ++      G     T  + +      S     
Sbjct: 832  ----KDKLDLSE-CVDKIKEKDKLYSH-HTEKCHKEGEKSKNTAAIKKTDDREKSREKMD 885

Query: 175  TEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGE 234
             +H   +P K   + +        + +  +D+     S   +   K   +D K   +  E
Sbjct: 886  RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE 945

Query: 235  KMPVTASVLSEEEQTHCLEIGSNTRHGKS-NLSEGKKSAELNSPLRERLSPENRTTDLKC 293
             + +T S   +EE+   +  G+  +H K  +L E  K   L +P  +    +++  D + 
Sbjct: 946  SINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDID-RY 1004

Query: 294  DSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENK---------WSQEKHSPWE 344
                  + +I     ++++ +   P     P S+    + K          S E+    +
Sbjct: 1005 KERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLK 1064

Query: 345  GVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPN 397
             +     H++ K      K++++E+E     + L + I + +    +P    N
Sbjct: 1065 DLEIEQWHKKHK-----EKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKN 1112


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 64/353 (18%), Positives = 136/353 (38%), Gaps = 31/353 (8%)

Query: 55   KYVKLKNYLKEICESEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKK 114
            K + ++   K I ES++K   R+Q   K  E+++          EK +K+K E++++   
Sbjct: 804  KEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTF------EKEKKIKHEHKSE--- 854

Query: 115  MLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFS 174
                KD L L E   D+ +EK  ++   ++      G     T  + +      S     
Sbjct: 855  ----KDKLDLSE-CVDKIKEKDKLYSH-HTEKCHKEGEKSKNTAAIKKTDDREKSREKMD 908

Query: 175  TEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGE 234
             +H   +P K   + +        + +  +D+     S   +   K   +D K   +  E
Sbjct: 909  RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKE 968

Query: 235  KMPVTASVLSEEEQTHCLEIGSNTRHGKS-NLSEGKKSAELNSPLRERLSPENRTTDLKC 293
             + +T S   +EE+   +  G+  +H K  +L E  K   L +P  +    +++  D + 
Sbjct: 969  SINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDID-RY 1027

Query: 294  DSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENK---------WSQEKHSPWE 344
                  + +I     ++++ +   P     P S+    + K          S E+    +
Sbjct: 1028 KERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLK 1087

Query: 345  GVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPN 397
             +     H++ K      K++++E+E     + L + I + +    +P    N
Sbjct: 1088 DLEIEQWHKKHK-----EKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKN 1135


>gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]
          Length = 880

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 55/270 (20%), Positives = 102/270 (37%), Gaps = 38/270 (14%)

Query: 435 SSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRK----- 489
           SS  S +  ST++PT  P  TP    P ++  Q V     H +   +  ++++ K     
Sbjct: 414 SSTMSAQAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGHHTHHQSDSPSSVVNKQLGSM 473

Query: 490 ALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLN------SVPTREQEVSSGC 543
           +L E+    +   S +     P +    S        + LN      S+ +  + + S C
Sbjct: 474 SLDEQQDNNNEKLSPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEWSSIASSSRGIGSHC 533

Query: 544 GDKSKKENVAADIPITETEAYQLLK--KATLQDNT---------NQTENRFQKT------ 586
             + ++E+      +   E     K  + + +D T         N  EN    T      
Sbjct: 534 KSEGQEESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEGVSAENPVENHINITQSDKFT 593

Query: 587 ----DASVSHLSGLNI--GSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKS 640
               D++    + LN+    G  E   +++ A E   S    +  + +EN   P    ++
Sbjct: 594 AKPLDSNSGERNDLNLDRSCGVPEESASSEKAKEPETSDQTSTESATNENNTNPEPQFQT 653

Query: 641 NALWDESDDSNSEIEAALRPRNHNTDDSDD 670
            A    + +  S  ++AL+    +TDDSDD
Sbjct: 654 EATGPSAHEETSTRDSALQ----DTDDSDD 679


>gi|54633315 deoxynucleotidyltransferase, terminal, interacting
           protein 2 [Homo sapiens]
          Length = 756

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 69/314 (21%), Positives = 113/314 (35%), Gaps = 63/314 (20%)

Query: 98  TEKLQKLKLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPAT 157
           + +L+ L    +T +++++  + S       T +++  V+VH  +NS   M       AT
Sbjct: 317 SSQLKNLSELQDTSLQQLVSQRHS-------TPQNKNAVSVHSNLNSEAVMKSLTQTFAT 369

Query: 158 IFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQC 217
           + +GR          ++   KSP         D         S +  +S V+  S D   
Sbjct: 370 VEVGR----------WNNNKKSP-----IKASDLTKFGDCGGSDDEEESTVISVSED--- 411

Query: 218 LNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAEL--- 274
           +N   N+D +   ++    P T    S+ +    L + S+    +S  SE ++       
Sbjct: 412 MNSEGNVDFECDTKLYTSAPNT----SQGKDNSVLLVLSSDESQQSENSENEEDTLCFVE 467

Query: 275 NSPLRERLSPENRTTDLKCDSS----SGSEGEILTREHIEVEEKRASPPVSPIPVSEYCE 330
           NS  RE LS +  T  L CD++      + G    +     EE +A         SE   
Sbjct: 468 NSGQRESLSGD--TGSLSCDNALFVIDTTPGMSADKNFYLEEEDKA---------SEVAI 516

Query: 331 SENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILE 390
            E K  +E     E  SDH                +E E+ +S   D   S     L L 
Sbjct: 517 EEEKEEEEDEKSEEDSSDH----------------DENEDEFSDEEDFLNSTKAKLLKLT 560

Query: 391 SPEPQPNPGGKMEG 404
           S    P    K  G
Sbjct: 561 SSSIDPGLSIKQLG 574


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 26/119 (21%), Positives = 58/119 (48%), Gaps = 1/119 (0%)

Query: 24  QHGLRDSEKKRLDLEK-KLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRNQEYLK 82
           Q  +R+ E+KR + EK +  E  Q    ++  +  K++   ++I E E+    + ++  +
Sbjct: 356 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGE 415

Query: 83  RFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEG 141
           + E++           EK+++ + +   Q KK+   ++ +  +EE+  E  EK+   EG
Sbjct: 416 QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG 474



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 25/123 (20%), Positives = 60/123 (48%), Gaps = 4/123 (3%)

Query: 18  ERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRN 77
           E++ + +  +R+ EKK  + E+K+ E  +     ++ +  K+     ++CE E K   + 
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEM----MQEQEEKMGEQEGKMCEQEAKMQEQE 487

Query: 78  QEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEELTDEDREKVA 137
           ++  ++ E+++          EK+++ +   + Q +KM   ++ +  +EE   E  EK+ 
Sbjct: 488 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 547

Query: 138 VHE 140
             E
Sbjct: 548 RQE 550



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 24/129 (18%), Positives = 62/129 (48%), Gaps = 10/129 (7%)

Query: 18  ERLGQLQHGLRDSEKKRLDLEKKLYEYN---QSDTCRVKLKYVKLKNYLKEICESEKKAH 74
           E++ + +  +++ E+K  + E+K++E     Q    +++ +  K++   K+I E E+K  
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIR 456

Query: 75  TRNQEYLKRFERVQ-------AHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEE 127
            + +   ++ E++                  EK+++ + +   Q KK+   ++ +  +EE
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516

Query: 128 LTDEDREKV 136
           +  E  EK+
Sbjct: 517 MMQEQEEKM 525



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 23/122 (18%), Positives = 59/122 (48%), Gaps = 4/122 (3%)

Query: 18  ERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRN 77
           E++ + +  +++ E+K  + E K+ E       +++ +  K++   ++I E EKK   + 
Sbjct: 453 EKIREQEEMMQEQEEKMGEQEGKMCEQE----AKMQEQEEKMRRQEEKIREQEKKIREQE 508

Query: 78  QEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEELTDEDREKVA 137
           ++  ++ E +Q          EK+ + + + + Q +KM   ++ +  +E    +  EK+ 
Sbjct: 509 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568

Query: 138 VH 139
            H
Sbjct: 569 EH 570


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 92/458 (20%), Positives = 187/458 (40%), Gaps = 71/458 (15%)

Query: 15   DYYERLGQLQHGLRDSEKKRLDLEKKLYEYN------QSDTCRVKLKYVKLKNYLKEICE 68
            D  E   QL+  L++ ++K L LE+K  E        ++D+  VK    +    L++  +
Sbjct: 699  DKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQ 758

Query: 69   SEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEEL 128
                   R  E  K+ E ++  +V  T       +L L+ +++  +         +K++L
Sbjct: 759  LNTDLELRATELSKQLE-MEKEIVSST-------RLDLQKKSEALE--------SIKQKL 802

Query: 129  TDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSI 188
            T ++ EK  + +   + +  ++  ++       R  + +  ++    E K    T+  ++
Sbjct: 803  TKQEEEKQILKQDFETLSQETKIQHEELN---NRIQTTVTELQKVKME-KEALMTELSTV 858

Query: 189  PDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQ 248
             D        + S V+DS       +++   + +N  GKA++   EK   T   L  + Q
Sbjct: 859  KD--------KLSKVSDSL-----KNSKSEFEKENQKGKAAILDLEK---TCKELKHQLQ 902

Query: 249  THCLEIGSNTRHGKSNLSEGKKSA-----ELNSPLRERLSPEN--RTTDLKCDSSSGSEG 301
                      +  K +L + K+++     ELNS   + +  +N  +  + +     G+  
Sbjct: 903  VQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNIN 962

Query: 302  EILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDH------LAHREP 355
            E+      + ++  A      I V +  E ENK  Q+     + ++        L +   
Sbjct: 963  ELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYE 1022

Query: 356  KSQKPFRKMQEE----EEESWSTSSDL-----TISISEDDLILESPEPQPNPGGKMEGED 406
            KSQ+ F+++Q +    E E  +T  DL      +S++++DLI  S   Q     K+    
Sbjct: 1023 KSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLI--SNRNQIGNQNKL---- 1076

Query: 407  GIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESS 444
             I+ LK   A  E+ +   E+    +  +  D +KE S
Sbjct: 1077 -IQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKS 1113


>gi|224586823 coiled-coil domain containing 110 isoform b [Homo
           sapiens]
          Length = 796

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 33/121 (27%), Positives = 61/121 (50%), Gaps = 15/121 (12%)

Query: 20  LGQLQHGLRDSEKKRL---------DLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESE 70
           L Q +H ++D E++           + EK     + ++ C  K++Y  L+NYLKE  + +
Sbjct: 348 LDQTKHEMKDKERQPFLVKQGSIISENEKTSKVNSVTEQCVAKIQY--LQNYLKESVQIQ 405

Query: 71  KKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEELTD 130
           KK      E L    +++  +  FTT +  +QK++  YE Q+K ++  K ++  K   T+
Sbjct: 406 KKVMELESENLNLKSKMKPLI--FTTQS-LIQKVE-TYEKQLKNLVEEKSTIQSKLSKTE 461

Query: 131 E 131
           E
Sbjct: 462 E 462


>gi|22749515 coiled-coil domain containing 110 isoform a [Homo
           sapiens]
          Length = 833

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 33/121 (27%), Positives = 61/121 (50%), Gaps = 15/121 (12%)

Query: 20  LGQLQHGLRDSEKKRL---------DLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESE 70
           L Q +H ++D E++           + EK     + ++ C  K++Y  L+NYLKE  + +
Sbjct: 385 LDQTKHEMKDKERQPFLVKQGSIISENEKTSKVNSVTEQCVAKIQY--LQNYLKESVQIQ 442

Query: 71  KKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEELTD 130
           KK      E L    +++  +  FTT +  +QK++  YE Q+K ++  K ++  K   T+
Sbjct: 443 KKVMELESENLNLKSKMKPLI--FTTQS-LIQKVE-TYEKQLKNLVEEKSTIQSKLSKTE 498

Query: 131 E 131
           E
Sbjct: 499 E 499


>gi|34996489 pleckstrin homology domain interacting protein [Homo
            sapiens]
          Length = 1821

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 68/291 (23%), Positives = 124/291 (42%), Gaps = 48/291 (16%)

Query: 176  EHKSPQPTKNFSIPDPHSH---------RQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDG 226
            E+K P  +KN +    H H         +QT Q +  T S + +T   ++ +      +G
Sbjct: 765  ENKIPTVSKNHA----HEHFLDLGESKKQQTNQHNYRTRSALEETPRPSEEIE-----NG 815

Query: 227  KASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPEN 286
             +S   GE + V+    SEEE+      GS++ +  S+ S+    A +N    +++ P+N
Sbjct: 816  SSSSDEGEVVAVSGGT-SEEEERAWHSDGSSSDYS-SDYSDWTADAGINLQPPKKV-PKN 872

Query: 287  RTTDLKCDSSSGSEGEILTREHIEVEEKRASP----PVSP------------IPVSEYCE 330
            +T   +  S    E E   ++ I+ E+K+ +     P+SP            + V E   
Sbjct: 873  KTKKAESSSDEEEESEKQKQKQIKKEKKKVNEEKDGPISPKKKKPKERKQKRLAVGEL-- 930

Query: 331  SENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILE 390
            +EN  + E+  P   ++D +  R      PF     +E   +    +  + ++  + I  
Sbjct: 931  TENGLTLEEWLPSTWITDTIPRR-----CPFVPQMGDEVYYFRQGHEAYVEMARKNKIY- 984

Query: 391  SPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEK 441
            S  P+  P  KME  +  E +K++  + E V L T   C+      PD+ K
Sbjct: 985  SINPKKQPWHKMELREQ-ELMKIVGIKYE-VGLPT-LCCLKLAFLDPDTGK 1032


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 103/519 (19%), Positives = 192/519 (36%), Gaps = 59/519 (11%)

Query: 170  MRDFSTEHKSPQPTKNF-SIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGK- 227
            M D +   ++  P++ F +I    S   + + S   D   V   N     +K+D  DGK 
Sbjct: 1143 MSDETNNEETESPSQEFVNITKYESSLYSQEYSKPAD---VTPLNGFSEGSKTDATDGKD 1199

Query: 228  -----ASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERL 282
                 +++     M       S     +C E+ ++T     +      S +++      L
Sbjct: 1200 YNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSL 1259

Query: 283  SPENRTTDLKCDSSSGSEGEILTREHIEV----EEKRASPPVSPIPVSEYCESENKWSQE 338
            SP   +   K      S    LT   I+V    E    SP V+   V E+C S    + E
Sbjct: 1260 SPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPEDKTLE 1319

Query: 339  KHSPWEGVSDHLAH----REPKSQKPFRKMQE--EEEESWSTSSDLTISISEDDLILESP 392
              SP + V+    H    + P  +K      E  E+  +   S + + +  E++    SP
Sbjct: 1320 VVSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKPPAVPVSFEFSDAKDENERASVSP 1379

Query: 393  EPQPNPGGKMEGEDGIEALK---LIHAEQERVA-LSTEKNCILQTLSSPDSEKESSTNAP 448
              +P P  +   E  +  L+   LI +E    + LS +     +   SP  EK     +P
Sbjct: 1380 MDEPVPDSESPIEKVLSPLRSPPLIGSESAYESFLSADDKASGRGAESPFEEKSGKQGSP 1439

Query: 449  TREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSC 508
             +    +P S++    + Q            K+E  +     + E+ G+       E+  
Sbjct: 1440 DQ---VSPVSEMTSTSLYQD-----------KQEGKSTDFAPIKEDFGQEKKTDDVEAMS 1485

Query: 509  SLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLK 568
            S P++  D   + +  P                   D S+  +   D  ++ +E     K
Sbjct: 1486 SQPALALDERKLGDVSPTQI----------------DVSQFGSFKEDTKMSISEGTVSDK 1529

Query: 569  KATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRH 628
             AT  D     E+ +   +  V+ +S  ++ + +F   T + ++   S  +  GSP S  
Sbjct: 1530 SATPVDE-GVAEDTYSHME-GVASVSTASVATSSFPEPTTDDVS--PSLHAEVGSPHSTE 1585

Query: 629  ENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDD 667
             +    V  +++   + E++ S S+ E   RP + +  D
Sbjct: 1586 VDDSLSVSVVQTPTTFQETEMSPSK-EECPRPMSISPPD 1623


>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
          Length = 783

 Score = 37.7 bits (86), Expect = 0.035
 Identities = 35/147 (23%), Positives = 72/147 (48%), Gaps = 13/147 (8%)

Query: 12  SSPDYYERLGQLQHGLRDSEKKRLDLEKKLYEYNQ---SDTCRVKLKYVKLKNYLKEICE 68
           S  +  E+L Q +  + D+E+K LDL++KL   ++   +DTC  + +  +L+  +KE  +
Sbjct: 334 SQNNLQEKLVQEKSKVADAEEKILDLQRKLEHAHKVCLTDTCISEKQ--QLEEKIKEATQ 391

Query: 69  SEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEE- 127
           +E K   + QE     E+ +  +++   +    Q   L+ +  + +M CS+    ++++ 
Sbjct: 392 NEAKVKQQYQE-----EQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQSRIQQQE 446

Query: 128 --LTDEDREKVAVHEGINSGTAMSRGL 152
             L   + EK    E + S   +S  L
Sbjct: 447 ALLKQLENEKRKYDEHVKSNQELSEKL 473


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 37.7 bits (86), Expect = 0.035
 Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 1/111 (0%)

Query: 28  RDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRNQEYLKRFERV 87
           +  E+  L+ EKK  E  + +  +++ +  +L   LK+I E  KKA    +E  +R   +
Sbjct: 316 KQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALEL 375

Query: 88  QAHVVHFTTNTEKLQKLKLEYETQIKKML-CSKDSLGLKEELTDEDREKVA 137
           +       +  EKL K + E E   + +L  S+D    +E+L  E  E  A
Sbjct: 376 EQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTA 426


>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
          Length = 556

 Score = 37.7 bits (86), Expect = 0.035
 Identities = 87/416 (20%), Positives = 152/416 (36%), Gaps = 63/416 (15%)

Query: 226 GKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPE 285
           G++ L+  EK  +   V  EEE        + +R  K +L+  KK     +P  +   PE
Sbjct: 38  GRSHLEPEEKQALKRLV--EEELLKMQVDEAASREDKLDLT--KKGKRPPTPCSD---PE 90

Query: 286 NRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEG 345
            +      +S SGSE                 PP      +E   ++ +  +      E 
Sbjct: 91  RKRFRFNSESESGSEAS---------SPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEE 141

Query: 346 VSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTI---------SISEDDLILESPEPQP 396
            SD    R+  +Q+     +EEE+     +    +         S+S      ES E + 
Sbjct: 142 SSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAREESEESEA 201

Query: 397 NP----GGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREP 452
            P      K+EG  G ++LK    E E   L+ +K            ++E       +E 
Sbjct: 202 EPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKK-----------EQREEEVEEEEKEE 250

Query: 453 GQTPDSDVPRAQV-GQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSL- 510
            +      PR +  G+  +  +E     K +A  LL  + +EE  + +A    +S     
Sbjct: 251 DEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDRE 310

Query: 511 PSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKA 570
           P +   +    + K    L+   + E E  SG G+ + K +                +K 
Sbjct: 311 PPVQRKSEDRTQLKGGKRLSG--SSEDEEDSGKGEPTAKGS----------------RKM 352

Query: 571 TLQDNTNQTENRFQKTDASVSHLSGLNIG--SGAFETKTANKIASEASFSSSEGSP 624
               +T+  E+  ++ + S S   G   G        K++ K  + +S SSS+GSP
Sbjct: 353 ARLGSTSGEESDLER-EVSDSEAGGGPQGERKNRSSKKSSRKGRTRSSSSSSDGSP 407


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 37.4 bits (85), Expect = 0.045
 Identities = 24/123 (19%), Positives = 61/123 (49%), Gaps = 4/123 (3%)

Query: 18  ERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRN 77
           E++ + +  +R+ E+K  + E+K+ E  +      + +  K+    +++CE E+K   + 
Sbjct: 578 EKVWRQEEKIREQEEKIREQEEKIREQEEM----TQEQEEKMGEQEEKMCEQEEKMQEQE 633

Query: 78  QEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEELTDEDREKVA 137
           ++  ++ E+++          EK+++ +   + Q +KM   ++ +  +EE   E  EK+ 
Sbjct: 634 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 693

Query: 138 VHE 140
             E
Sbjct: 694 RQE 696



 Score = 33.1 bits (74), Expect = 0.86
 Identities = 23/123 (18%), Positives = 61/123 (49%), Gaps = 4/123 (3%)

Query: 18  ERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRN 77
           E++ + +   ++ E+K  + E+K+ E  +    +++ +  K++   ++I E EKK   + 
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEE----KMQEQEEKMRRQEEKIREQEKKIREQE 654

Query: 78  QEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEELTDEDREKVA 137
           ++  ++ E +Q          EK+ + + + + Q +KM   ++ +  +E    +  EK+ 
Sbjct: 655 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714

Query: 138 VHE 140
            H+
Sbjct: 715 EHQ 717



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 20/95 (21%), Positives = 48/95 (50%), Gaps = 4/95 (4%)

Query: 18  ERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRN 77
           E++ + +  +R+ EKK  + E+K+ E  +     ++ +  K+    +++CE E+K   + 
Sbjct: 634 EKMRRQEEKIREQEKKIREQEEKIREQEEM----MQEQEEKMWEQEEKMCEQEEKMQEQE 689

Query: 78  QEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQI 112
           ++  ++ E++    V      EK+Q+ +   E  I
Sbjct: 690 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 26/136 (19%), Positives = 62/136 (45%), Gaps = 13/136 (9%)

Query: 18  ERLGQLQHGLRDSEKKRLDLEKKLYEYN----------QSDTCRVKLKYVKLKNYLKE-- 65
           E++ + +  +R+ E+K    E+K++E            Q +  R + K  + +   ++  
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543

Query: 66  -ICESEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGL 124
            I E E+K   + ++  ++ E++           EK+ + + +   Q +K+   ++ +  
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603

Query: 125 KEELTDEDREKVAVHE 140
           +EE+T E  EK+   E
Sbjct: 604 QEEMTQEQEEKMGEQE 619



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 24/117 (20%), Positives = 55/117 (47%), Gaps = 4/117 (3%)

Query: 18  ERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRN 77
           E   + +  + + E+K  + E+K+ E  +    +++ +  K++   K+I E E+K   + 
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEE----KMRRQEEKIREQEKKIREQEEKIREQE 661

Query: 78  QEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEELTDEDRE 134
           +   ++ E++           EK+Q+ + +   Q +KM   +  L  +EE   E +E
Sbjct: 662 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718


>gi|190194423 SPARC-like 1 [Homo sapiens]
          Length = 664

 Score = 37.4 bits (85), Expect = 0.045
 Identities = 62/319 (19%), Positives = 121/319 (37%), Gaps = 39/319 (12%)

Query: 365 QEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALS 424
           +E E+E+  ++ D +   +E   +L+S E       + +G+   + L L   E     LS
Sbjct: 50  EENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAE-QGKSSSQELGLKDQEDSDGHLS 108

Query: 425 -------TEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDN 477
                  TE    ++   S   EK+ S N     PG +  +D   +   + +   +E+  
Sbjct: 109 VNLEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTD---SNQQESITKREENQE 165

Query: 478 SVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILN-DNSGIKEAKPAVWLNSVPTRE 536
             +  +   L ++     G R   +  +     P+I N +    KE       N    R+
Sbjct: 166 QPRNYSHHQLNRSSKHSQGLRDQGNQEQD----PNISNGEEEEEKEPGEVGTHNDNQERK 221

Query: 537 QEVS-SGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSG 595
            E+       K +++N  +D  + E++    + K    +     + +   ++A +   + 
Sbjct: 222 TELPREHANSKQEEDNTQSDDILEESDQPTQVSKMQEDEFDQGNQEQEDNSNAEMEEENA 281

Query: 596 LNIGSGAFETKTANKIASEASFSSSEGSP----LSRHENKKKPVINLKSNALWDESDDSN 651
            N+          NK   E  + S EG      +S H+  ++  ++     L + +DD N
Sbjct: 282 SNV----------NKHIQETEWQSQEGKTGLEAISNHKETEEKTVS--EALLMEPTDDGN 329

Query: 652 SEIEAALRPRNHNTDDSDD 670
           +       PRNH  DD  D
Sbjct: 330 TT------PRNHGVDDDGD 342


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.123    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,525,708
Number of Sequences: 37866
Number of extensions: 1352522
Number of successful extensions: 4405
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 269
Number of HSP's that attempted gapping in prelim test: 3947
Number of HSP's gapped (non-prelim): 648
length of query: 673
length of database: 18,247,518
effective HSP length: 109
effective length of query: 564
effective length of database: 14,120,124
effective search space: 7963749936
effective search space used: 7963749936
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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