Search of human proteins with 117956391

Search of human proteins with 117956391

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117956391 protease, serine, 33 [Homo sapiens]
         (280 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117956391 protease, serine, 33 [Homo sapiens]                      588   e-168
gi|4506153 prostasin preproprotein [Homo sapiens]                     257   9e-69
gi|13994276 marapsin [Homo sapiens]                                   254   4e-68
gi|11545839 protease, serine, 22 [Homo sapiens]                       244   8e-65
gi|58218970 protease, serine, 36 [Homo sapiens]                       230   1e-60
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      226   2e-59
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           222   2e-58
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            217   1e-56
gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  216   2e-56
gi|33695155 hepsin [Homo sapiens]                                     203   1e-52
gi|4504481 hepsin [Homo sapiens]                                      203   1e-52
gi|148806900 epidermis-specific serine protease-like protein [Ho...   194   6e-50
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             194   7e-50
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         193   1e-49
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]          193   2e-49
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]           192   4e-49
gi|4505881 plasminogen [Homo sapiens]                                 189   2e-48
gi|21614531 testisin isoform 2 [Homo sapiens]                         189   3e-48
gi|5803197 testisin isoform 1 [Homo sapiens]                          188   5e-48
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   184   6e-47
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa...   183   2e-46
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap...   183   2e-46
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          182   2e-46
gi|194018492 transmembrane protease, serine 11F [Homo sapiens]        181   5e-46
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         181   5e-46
gi|34098976 marapsin 2 [Homo sapiens]                                 181   8e-46
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...   180   1e-45
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...   180   1e-45
gi|223942069 enterokinase precursor [Homo sapiens]                    177   1e-44
gi|4503627 coagulation factor XI precursor [Homo sapiens]             176   3e-44

>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  588 bits (1517), Expect = e-168
 Identities = 280/280 (100%), Positives = 280/280 (100%)

Query: 1   MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAH 60
           MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAH
Sbjct: 1   MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAH 60

Query: 61  VCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSE 120
           VCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSE
Sbjct: 61  VCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSE 120

Query: 121 DGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPL 180
           DGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPL
Sbjct: 121 DGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPL 180

Query: 181 QGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQS 240
           QGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQS
Sbjct: 181 QGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQS 240

Query: 241 GSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF 280
           GSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
Sbjct: 241 GSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF 280


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  257 bits (656), Expect = 9e-69
 Identities = 128/275 (46%), Positives = 170/275 (61%), Gaps = 7/275 (2%)

Query: 9   VLLLLVLG----AAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGG 64
           V +LL LG      G +G + A CG    + RI GG     G+WPWQ SI + G HVCGG
Sbjct: 15  VAILLYLGLLRSGTGAEGAE-APCGVAPQA-RITGGSSAVAGQWPWQVSITYEGVHVCGG 72

Query: 65  SLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGAR 124
           SL++ QWVL+AAHCFP       Y V+LGA +L S S       ++ ++  P Y ++G++
Sbjct: 73  SLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQ 132

Query: 125 GDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVR 184
           GD+ALLQL RP+  S  ++P+CLP   A  P G  C VTGWG + P V L   +PLQ + 
Sbjct: 133 GDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLE 192

Query: 185 VPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWV 244
           VPL+   TC+ LY++ A  P+    V    +CAGY +G KDACQGDSGGPL+C   G W 
Sbjct: 193 VPLISRETCNCLYNIDAK-PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWY 251

Query: 245 LVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVS 279
           L G+VSWG  C   NRPGVYT  ++Y+ WIQ++V+
Sbjct: 252 LTGIVSWGDACGARNRPGVYTLASSYASWIQSKVT 286


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  254 bits (650), Expect = 4e-68
 Identities = 128/274 (46%), Positives = 169/274 (61%), Gaps = 2/274 (0%)

Query: 1   MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAH 60
           MR  + + +LLLL  G+   + + + ACG+PRM +R+VGG+D ++GEWPWQ SIQ  G+H
Sbjct: 1   MRRPAAVPLLLLLCFGSQ--RAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSH 58

Query: 61  VCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSE 120
            CGGSLIA QWVLTAAHCF   +  + Y+V LGA +L    P  +   VR+V   P Y  
Sbjct: 59  FCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQG 118

Query: 121 DGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPL 180
             +  D+AL++L  PVP +  + PVCLP P      G  C VTGWGS      LPE R L
Sbjct: 119 TASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRIL 178

Query: 181 QGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQS 240
           Q + VP++D+  C+ LY    +     + +    LCAG+ +G KDAC+GDSGGPL CL  
Sbjct: 179 QKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVG 238

Query: 241 GSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWI 274
            SW+  GV+SWG+GCA  NRPGVY  V  +  WI
Sbjct: 239 QSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWI 272


>gi|11545839 protease, serine, 22 [Homo sapiens]
          Length = 317

 Score =  244 bits (622), Expect = 8e-65
 Identities = 118/251 (47%), Positives = 159/251 (63%), Gaps = 6/251 (2%)

Query: 27  ACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRA-LP 85
           ACG+P+  +R+VGG D  D EWPW  SIQ  G H C GSL+  +WV+TAAHCF      P
Sbjct: 40  ACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKP 99

Query: 86  AEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYS-EDGARGDLALLQLRRPVPLSARVQP 144
             + V LGA +LG+   R+  V V  V   P YS ++GA  D+AL++L R +  S RV P
Sbjct: 100 YLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLP 159

Query: 145 VCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVP 204
           +CLP      PP T C ++GWGS++ GVPLP  + LQ ++VP++DS  C  LY  GA   
Sbjct: 160 ICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGA--- 216

Query: 205 QAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVY 264
             +  +    LCAGY +G +DAC GDSGGPL C   G+W+L G++SWG+GCA  NRPGVY
Sbjct: 217 -GQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVY 275

Query: 265 TSVATYSPWIQ 275
            S++ +  W++
Sbjct: 276 ISLSAHRSWVE 286


>gi|58218970 protease, serine, 36 [Homo sapiens]
          Length = 855

 Score =  230 bits (586), Expect = 1e-60
 Identities = 119/254 (46%), Positives = 147/254 (57%), Gaps = 4/254 (1%)

Query: 28  CGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRAL--- 84
           CG+P  S+RIVGG + + G WPWQ S+ H G H+CGGSLIAP WVL+AAHCF        
Sbjct: 38  CGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEP 97

Query: 85  PAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQP 144
            AE+ V LG            +  V  +++P +YS+     DLALL+L  P  L   V P
Sbjct: 98  AAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWP 157

Query: 145 VCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVP 204
           VCLP    R   GT C  TGWG ++   PLP    LQ V + LL   TC  LY       
Sbjct: 158 VCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFN 217

Query: 205 QAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVY 264
              +I LPG LCAGYP+G +D CQGDSGGPL C + G W   G+ S+G GC   NRPGV+
Sbjct: 218 LTLQI-LPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVF 276

Query: 265 TSVATYSPWIQARV 278
           T+VATY  WI+ +V
Sbjct: 277 TAVATYEAWIREQV 290



 Score =  117 bits (293), Expect = 1e-26
 Identities = 89/249 (35%), Positives = 118/249 (47%), Gaps = 38/249 (15%)

Query: 40  GRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCF--------PRRALPAEYRVR 91
           G+  R G WPW+A +   G+  C G+L++  WVL  A CF        P R L A +RV 
Sbjct: 326 GKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDA-WRVL 384

Query: 92  LGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPG 151
           L +        R  +  V R++   + S D A  DLALLQLR PV LSA  +PVCLP P 
Sbjct: 385 LPS--------RPRAERVARLVQHENASWDNA-SDLALLQLRTPVNLSAASRPVCLPHPE 435

Query: 152 ARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLY-HVGADVPQAERIV 210
               PG+ CR+  WG   P +      P   +   LL    C  LY   GA VP      
Sbjct: 436 HYFLPGSRCRLARWGRGEPAL-----GPGALLEAELLGGWWCHCLYGRQGAAVP------ 484

Query: 211 LPG----SLCAGYPQGHK-DACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYT 265
           LPG    +LC  Y +  +  +C  DS   L C + G+W L G+  +  GC    RP  + 
Sbjct: 485 LPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCL---RPRAFF 541

Query: 266 SVATYSPWI 274
            + T+ PWI
Sbjct: 542 PLQTHGPWI 550



 Score =  105 bits (261), Expect = 6e-23
 Identities = 73/209 (34%), Positives = 96/209 (45%), Gaps = 25/209 (11%)

Query: 48  WPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTS---PRT 104
           WPW A +   G  VC G L+AP WVL A HC  R        + +   R G++S      
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQ 660

Query: 105 LSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTG 164
           +S  V  + LP      G R  LALL+L   V  S    P+CL   G   PPG  C V G
Sbjct: 661 VSRLVISIRLPQHL---GLRPPLALLELSSRVEPSPSALPICLHPAGI--PPGASCWVLG 715

Query: 165 WGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHK 224
           W   +  VP+          V +L  R CD LY         + I+ PG+LC  Y +G +
Sbjct: 716 WKEPQDRVPV-------AAAVSILTQRICDCLY---------QGILPPGTLCVLYAEGQE 759

Query: 225 DACQGDSGGPLTC-LQSGSWVLVGVVSWG 252
           + C+  S  PL C +  GSW+LVG+   G
Sbjct: 760 NRCEMTSAPPLLCQMTEGSWILVGMAVQG 788


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  226 bits (575), Expect = 2e-59
 Identities = 128/275 (46%), Positives = 165/275 (60%), Gaps = 18/275 (6%)

Query: 11  LLLVLGAAGTQGRK-SAACGQPRMSS---RIVGGRDGRDGEWPWQASIQHRGAHVCGGSL 66
           LLL+L   G   R     CG+P++S    RIVGG     G WPWQAS++ R  HVCGGSL
Sbjct: 8   LLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSL 67

Query: 67  IAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYS-EDGARG 125
           ++PQWVLTAAHCF      ++Y+V LG L + + SP   +V  R+++L    S + G  G
Sbjct: 68  LSPQWVLTAAHCFSGSLNSSDYQVHLGELEI-TLSPHFSTV--RQIILHSSPSGQPGTSG 124

Query: 126 DLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRV 185
           D+AL++L  PV LS+R+ PVCLP       PG  C VTGWG  R G PLP    L+ V+V
Sbjct: 125 DIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKV 184

Query: 186 PLLDSRTCDGLYHVGADVP-QAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWV 244
            ++D+ TC        D P     I+ P  LCA   +G  DACQ DSGGPL C  +G+WV
Sbjct: 185 SVVDTETCR------RDYPGPGGSILQPDMLCA---RGPGDACQDDSGGPLVCQVNGAWV 235

Query: 245 LVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVS 279
             G+VSWG+GC  PNRPGVYT V  Y  WI+  ++
Sbjct: 236 QAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHIT 270


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  222 bits (566), Expect = 2e-58
 Identities = 124/255 (48%), Positives = 149/255 (58%), Gaps = 14/255 (5%)

Query: 28  CGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAE 87
           CG    SSRIVGG    +GEWPWQAS+Q RG H+CGG+LIA +WV+TAAHCF   ++ + 
Sbjct: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAST 627

Query: 88  --YRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPV 145
             + V LG +   S  P  +S  V R+LL P + ED    D+ALLQL  PV  SA V+PV
Sbjct: 628 VLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPV 687

Query: 146 CLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQ 205
           CLP       PG  C +TGWG+LR G P+     LQ V V L+    C  +Y        
Sbjct: 688 CLPARSHFFEPGLHCWITGWGALREGGPIS--NALQKVDVQLIPQDLCSEVYRYQ----- 740

Query: 206 AERIVLPGSLCAGYPQGHKDACQGDSGGPLTC-LQSGSWVLVGVVSWGKGCALPNRPGVY 264
               V P  LCAGY +G KDACQGDSGGPL C   SG W L G+VSWG GC  PN  GVY
Sbjct: 741 ----VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVY 796

Query: 265 TSVATYSPWIQARVS 279
           T +     WIQ  V+
Sbjct: 797 TRITGVISWIQQVVT 811


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  217 bits (552), Expect = 1e-56
 Identities = 120/269 (44%), Positives = 153/269 (56%), Gaps = 9/269 (3%)

Query: 10  LLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGA---HVCGGSL 66
           LLLL L    ++   + A GQ      IVGG++    +WPWQ S++  G    H CGGSL
Sbjct: 4   LLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSL 63

Query: 67  IAPQWVLTAAHCF-PRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARG 125
           I PQWVLTAAHC  P     A  RV+L    L         +PV R+++ P +       
Sbjct: 64  IHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQL---LPVSRIIVHPQFYTAQIGA 120

Query: 126 DLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRV 185
           D+ALL+L  PV +S+ V  V LP      PPG PC VTGWG +     LP   PL+ V+V
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180

Query: 186 PLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVL 245
           P++++  CD  YH+GA      RIV    LCAG     +D+CQGDSGGPL C  +G+W+ 
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQ 238

Query: 246 VGVVSWGKGCALPNRPGVYTSVATYSPWI 274
            GVVSWG+GCA PNRPG+YT V  Y  WI
Sbjct: 239 AGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267


>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  216 bits (550), Expect = 2e-56
 Identities = 120/269 (44%), Positives = 153/269 (56%), Gaps = 9/269 (3%)

Query: 10  LLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGA---HVCGGSL 66
           LLLL L    ++   + A GQ      IVGG++    +WPWQ S++ R     H CGGSL
Sbjct: 4   LLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSL 63

Query: 67  IAPQWVLTAAHCF-PRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARG 125
           I PQWVLTAAHC  P     A  RV+L    L         +PV R+++ P +       
Sbjct: 64  IHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQL---LPVSRIIVHPQFYTAQIGA 120

Query: 126 DLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRV 185
           D+ALL+L  PV +S+ V  V LP      PPG PC VTGWG +     LP   PL+ V+V
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180

Query: 186 PLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVL 245
           P++++  CD  YH+GA      RIV    LCAG     +D+CQGDSGGPL C  +G+W+ 
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQ 238

Query: 246 VGVVSWGKGCALPNRPGVYTSVATYSPWI 274
            GVVSWG+GCA PNRPG+YT V  Y  WI
Sbjct: 239 AGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  203 bits (517), Expect = 1e-52
 Identities = 116/265 (43%), Positives = 151/265 (56%), Gaps = 35/265 (13%)

Query: 28  CGQPRMS-SRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFP-RRALP 85
           CG+ ++   RIVGGRD   G WPWQ S+++ GAH+CGGSL++  WVLTAAHCFP R  + 
Sbjct: 153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVL 212

Query: 86  AEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDY-------SEDGARGDLALLQLRRPVPL 138
           + +RV  GA  +   SP  L + V+ V+    Y       SE+ +  D+AL+ L  P+PL
Sbjct: 213 SRWRVFAGA--VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENS-NDIALVHLSSPLPL 269

Query: 139 SARVQPVCLPVPGARPPPGTPCRVTGWGSL-----RPGVPLPEWRPLQGVRVPLLDSRTC 193
           +  +QPVCLP  G     G  C VTGWG+      + GV       LQ  RVP++ +  C
Sbjct: 270 TEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV-------LQEARVPIISNDVC 322

Query: 194 DGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGS----WVLVGVV 249
           +G    G  +        P   CAGYP+G  DACQGDSGGP  C  S S    W L G+V
Sbjct: 323 NGADFYGNQIK-------PKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIV 375

Query: 250 SWGKGCALPNRPGVYTSVATYSPWI 274
           SWG GCAL  +PGVYT V+ +  WI
Sbjct: 376 SWGTGCALAQKPGVYTKVSDFREWI 400


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  203 bits (517), Expect = 1e-52
 Identities = 116/265 (43%), Positives = 151/265 (56%), Gaps = 35/265 (13%)

Query: 28  CGQPRMS-SRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFP-RRALP 85
           CG+ ++   RIVGGRD   G WPWQ S+++ GAH+CGGSL++  WVLTAAHCFP R  + 
Sbjct: 153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVL 212

Query: 86  AEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDY-------SEDGARGDLALLQLRRPVPL 138
           + +RV  GA  +   SP  L + V+ V+    Y       SE+ +  D+AL+ L  P+PL
Sbjct: 213 SRWRVFAGA--VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENS-NDIALVHLSSPLPL 269

Query: 139 SARVQPVCLPVPGARPPPGTPCRVTGWGSL-----RPGVPLPEWRPLQGVRVPLLDSRTC 193
           +  +QPVCLP  G     G  C VTGWG+      + GV       LQ  RVP++ +  C
Sbjct: 270 TEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGV-------LQEARVPIISNDVC 322

Query: 194 DGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGS----WVLVGVV 249
           +G    G  +        P   CAGYP+G  DACQGDSGGP  C  S S    W L G+V
Sbjct: 323 NGADFYGNQIK-------PKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIV 375

Query: 250 SWGKGCALPNRPGVYTSVATYSPWI 274
           SWG GCAL  +PGVYT V+ +  WI
Sbjct: 376 SWGTGCALAQKPGVYTKVSDFREWI 400


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  194 bits (494), Expect = 6e-50
 Identities = 105/270 (38%), Positives = 151/270 (55%), Gaps = 13/270 (4%)

Query: 11  LLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQ 70
           LLL+LG +         CGQP  SSR+VGG+D   G WPWQ S+      +CGGSL++ +
Sbjct: 10  LLLLLGIS--------VCGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSER 61

Query: 71  WVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALL 130
            +LTAAHC         Y V LG++ +G +  R +   V ++++ P Y +  A  D+ALL
Sbjct: 62  LILTAAHCIQPTWTTFSYTVWLGSITVGDSRKR-VKYYVSKIVIHPKYQDTTA--DVALL 118

Query: 131 QLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDS 190
           +L   V  ++ + P+CLP    +      C VTGWG ++          LQ   VP++D 
Sbjct: 119 KLSSQVTFTSAILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDR 178

Query: 191 RTCDGLYH-VGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVV 249
           + C+ LY+ +G  +P  E ++    +CAG  Q  KD+C+GDSGGPL+C   G W+  GVV
Sbjct: 179 QACEQLYNPIGIFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVV 238

Query: 250 SWGKGCALPNRPGVYTSVATYSPWIQARVS 279
           SWG  C   + PGVYT+V  Y  WI A +S
Sbjct: 239 SWGLECG-KSLPGVYTNVIYYQKWINATIS 267


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  194 bits (493), Expect = 7e-50
 Identities = 107/272 (39%), Positives = 145/272 (53%), Gaps = 20/272 (7%)

Query: 13  LVLGAAGTQGRKSAACGQ-------PRMSSRIVGGRDGRDGEWPWQASIQHR---GAHVC 62
           +  G  G+ G     C          + S+RIVGG +   GEWPWQ S+Q +     H+C
Sbjct: 360 IAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLC 419

Query: 63  GGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDG 122
           GGSLI  QWVLTAAHCF    L   +R+  G L L   +  T    ++ +++  +Y    
Sbjct: 420 GGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSE 479

Query: 123 ARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQG 182
              D+AL++L+ P+  +   +P+CLP  G      T C VTGWG  +    +     LQ 
Sbjct: 480 GNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNI--LQK 537

Query: 183 VRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGS 242
           V +PL+ +  C   Y    D    +R+V     CAGY +G KDAC+GDSGGPL C  +G 
Sbjct: 538 VNIPLVTNEECQKRYQ---DYKITQRMV-----CAGYKEGGKDACKGDSGGPLVCKHNGM 589

Query: 243 WVLVGVVSWGKGCALPNRPGVYTSVATYSPWI 274
           W LVG+ SWG+GCA   +PGVYT VA Y  WI
Sbjct: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  193 bits (491), Expect = 1e-49
 Identities = 103/264 (39%), Positives = 149/264 (56%), Gaps = 12/264 (4%)

Query: 22  GRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPR 81
           G +  ACG   + + + GG +   G WPWQAS++ R  H CGGSL++ +WVL+AAHCF +
Sbjct: 40  GGREEACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQK 99

Query: 82  RALPAEYRVRLGALRLGSTSPRTLSV-----PVRRVLLPPDYSEDGARGDLALLQLRRPV 136
              P+E+ V+LG L    T P  L        V+ +++ PD +    R D+ALL+L   V
Sbjct: 100 HYYPSEWTVQLGELTSRPT-PWNLRAYSSRYKVQDIIVNPD-ALGVLRNDIALLRLASSV 157

Query: 137 PLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRP-GVPLPEWRPLQGVRVPLLDSRTCDG 195
             +A +QP+C+            C VTGWG + P G PLP    L+  +V +L++  C+ 
Sbjct: 158 TYNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNY 217

Query: 196 LYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGC 255
           L+    + P +  ++     CAG   G  D C+GDSGGPL C + G W  VG+VSWG  C
Sbjct: 218 LF----EQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDC 273

Query: 256 ALPNRPGVYTSVATYSPWIQARVS 279
             PNRPGVYT+++ Y  WI+  +S
Sbjct: 274 GQPNRPGVYTNISVYFHWIRRVMS 297


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score =  193 bits (490), Expect = 2e-49
 Identities = 108/254 (42%), Positives = 140/254 (55%), Gaps = 13/254 (5%)

Query: 24  KSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFP--R 81
           + + CG   ++SRIVGG+    G WPWQAS+     H CGGS++AP+WV+TAAHC    R
Sbjct: 205 RCSECGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFR 264

Query: 82  RALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSAR 141
            A  + +RV  G +   +  P   ++ V R++  P YS      D+ALL+L+  +  S  
Sbjct: 265 LARLSSWRVHAGLVSHSAVRPHQGAL-VERIIPHPLYSAQNHDYDVALLRLQTALNFSDT 323

Query: 142 VQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDG-LYHVG 200
           V  VCLP      P G+ C V+GWG   P         LQ   VPL  ++ C+    + G
Sbjct: 324 VGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSS-DMLQDTVVPLFSTQLCNSSCVYSG 382

Query: 201 ADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNR 260
           A        + P  LCAGY  G  DACQGDSGGPL C    +W LVGVVSWG+GCA PN 
Sbjct: 383 A--------LTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNH 434

Query: 261 PGVYTSVATYSPWI 274
           PGVY  VA +  WI
Sbjct: 435 PGVYAKVAEFLDWI 448


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score =  192 bits (487), Expect = 4e-49
 Identities = 111/250 (44%), Positives = 136/250 (54%), Gaps = 16/250 (6%)

Query: 28   CG-QPRMSSRIVGGRDGRDGEWPWQASIQ-HRGAHVCGGSLIAPQWVLTAAHCFPRRALP 85
            CG  P   +RIVGG     GEWPWQ S+   R  H CG  L+A +W+L+AAHCF     P
Sbjct: 817  CGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDP 876

Query: 86   AEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPV 145
             ++   LG   L     +   V   R+   P Y+      D+ALL+L  PV  S  V+P+
Sbjct: 877  KQWAAFLGTPFLSGAEGQLERVA--RIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPI 934

Query: 146  CLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQ 205
            CLP P  RPP GT C +TGWGS+R G  +   R LQ   V LL  +TC   Y V      
Sbjct: 935  CLPEPAPRPPDGTRCVITGWGSVREGGSMA--RQLQKAAVRLLSEQTCRRFYPVQ----- 987

Query: 206  AERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQ-SGSWVLVGVVSWGKGCALPNRPGVY 264
                +    LCAG+PQG  D+C GD+GGPL C + SG WVL GV SWG GC  P+ PGVY
Sbjct: 988  ----ISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVY 1043

Query: 265  TSVATYSPWI 274
            T VA    WI
Sbjct: 1044 TRVAAVRGWI 1053



 Score =  184 bits (468), Expect = 6e-47
 Identities = 104/251 (41%), Positives = 139/251 (55%), Gaps = 14/251 (5%)

Query: 28  CG-QP--RMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRAL 84
           CG QP  RM+ RIVGG +   GE+PWQAS++    H CG ++I  +W+++AAHCF     
Sbjct: 191 CGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQD 250

Query: 85  PAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQP 144
           P ++   +GA  L  +   T+   V +++  P Y+ D A  D+A+L+L  P+P    +QP
Sbjct: 251 PTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQP 310

Query: 145 VCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVP 204
           VCLP      PP   C ++GWG L+    L +   LQ   V LLD   C  LY       
Sbjct: 311 VCLPAATHIFPPSKKCLISGWGYLKEDF-LVKPEVLQKATVELLDQALCASLYGHSL--- 366

Query: 205 QAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQ-SGSWVLVGVVSWGKGCALPNRPGV 263
             +R+V     CAGY  G  D+CQGDSGGPL C + SG + L G+VSWG GCA   RPGV
Sbjct: 367 -TDRMV-----CAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGV 420

Query: 264 YTSVATYSPWI 274
           Y  V     WI
Sbjct: 421 YARVTRLRDWI 431



 Score =  172 bits (437), Expect = 2e-43
 Identities = 97/256 (37%), Positives = 142/256 (55%), Gaps = 17/256 (6%)

Query: 24  KSAACG-QPRMS--SRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFP 80
           K   CG +P M   +R+VGG     GE PWQ S++    H CG +++  +W+L+AAHCF 
Sbjct: 488 KLQECGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFN 547

Query: 81  RRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSA 140
              +  + R  LG   L       + + +RRV+L P Y+      DLA+L+L  P+  + 
Sbjct: 548 HTKVE-QVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNK 606

Query: 141 RVQPVCLPVPGARPPPGTPCRVTGWGSLRPG-VPLPEWRPLQGVRVPLLDSRTCDGLYHV 199
            +QPVCLP+   + P G  C ++GWG+ + G    PE   LQ   V ++D +TC  LY+ 
Sbjct: 607 YIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPEL--LQKASVGIIDQKTCSVLYNF 664

Query: 200 GADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQS-GSWVLVGVVSWGKGCALP 258
                  +R++     CAG+ +G  D+CQGDSGGPL C ++ G + L G+VSWG GCA  
Sbjct: 665 SL----TDRMI-----CAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQV 715

Query: 259 NRPGVYTSVATYSPWI 274
            +PGVYT +     WI
Sbjct: 716 KKPGVYTRITRLKGWI 731


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score =  189 bits (480), Expect = 2e-48
 Identities = 100/256 (39%), Positives = 142/256 (55%), Gaps = 26/256 (10%)

Query: 28  CGQPRMS-----SRIVGGRDGRDGEWPWQASIQHR-GAHVCGGSLIAPQWVLTAAHCFPR 81
           CG+P++       R+VGG       WPWQ S++ R G H CGG+LI+P+WVLTAAHC  +
Sbjct: 567 CGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEK 626

Query: 82  RALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSAR 141
              P+ Y+V LGA +  +  P    + V R+ L P       R D+ALL+L  P  ++ +
Sbjct: 627 SPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDK 680

Query: 142 VQPVCLPVPGARPPPGTPCRVTGWGSLRP--GVPLPEWRPLQGVRVPLLDSRTCDGLYHV 199
           V P CLP P       T C +TGWG  +   G  L     L+  ++P+++++ C+    +
Sbjct: 681 VIPACLPSPNYVVADRTECFITGWGETQGTFGAGL-----LKEAQLPVIENKVCNRYEFL 735

Query: 200 GADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPN 259
              V   E       LCAG+  G  D+CQGDSGGPL C +   ++L GV SWG GCA PN
Sbjct: 736 NGRVQSTE-------LCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPN 788

Query: 260 RPGVYTSVATYSPWIQ 275
           +PGVY  V+ +  WI+
Sbjct: 789 KPGVYVRVSRFVTWIE 804


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  189 bits (479), Expect = 3e-48
 Identities = 109/282 (38%), Positives = 156/282 (55%), Gaps = 23/282 (8%)

Query: 9   VLLLLVLGAAGTQGRKS-------AACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHV 61
           +LL L+L  AG +  +S         CG+  ++SRIVGG D   G WPWQ S++   +HV
Sbjct: 7   LLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHV 66

Query: 62  CGGSLIAPQWVLTAAHCFPRRAL-PAEYRVRLGALRLGSTSPRTLSVP-------VRRVL 113
           CG SL++ +W LTAAHCF      P+ + V+ G L   ++ P   S+        V  + 
Sbjct: 67  CGVSLLSHRWALTAAHCFETDLSDPSGWMVQFGQL---TSMPSFWSLQAYYTRYFVSNIY 123

Query: 114 LPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVP 173
           L P Y  +    D+AL++L  PV  +  +QP+CL          T C VTGWG ++    
Sbjct: 124 LSPRYLGNSPY-DIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEA 182

Query: 174 LPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGG 233
           LP    LQ V+V ++++  C+ L+   +      + +    +CAG  QG KDAC GDSGG
Sbjct: 183 LPSPHTLQEVQVAIINNSMCNHLFLKYS----FRKDIFGDMVCAGNAQGGKDACFGDSGG 238

Query: 234 PLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQ 275
           PL C ++G W  +GVVSWG GC  PNRPGVYT+++ +  WIQ
Sbjct: 239 PLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQ 280


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  188 bits (477), Expect = 5e-48
 Identities = 109/284 (38%), Positives = 157/284 (55%), Gaps = 25/284 (8%)

Query: 9   VLLLLVLGAAGTQGRKS-------AACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHV 61
           +LL L+L  AG +  +S         CG+  ++SRIVGG D   G WPWQ S++   +HV
Sbjct: 7   LLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWDSHV 66

Query: 62  CGGSLIAPQWVLTAAHCFPRRAL---PAEYRVRLGALRLGSTSPRTLSVP-------VRR 111
           CG SL++ +W LTAAHCF   +    P+ + V+ G L   ++ P   S+        V  
Sbjct: 67  CGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQL---TSMPSFWSLQAYYTRYFVSN 123

Query: 112 VLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPG 171
           + L P Y  +    D+AL++L  PV  +  +QP+CL          T C VTGWG ++  
Sbjct: 124 IYLSPRYLGNSPY-DIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKED 182

Query: 172 VPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDS 231
             LP    LQ V+V ++++  C+ L+   +      + +    +CAG  QG KDAC GDS
Sbjct: 183 EALPSPHTLQEVQVAIINNSMCNHLFLKYS----FRKDIFGDMVCAGNAQGGKDACFGDS 238

Query: 232 GGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQ 275
           GGPL C ++G W  +GVVSWG GC  PNRPGVYT+++ +  WIQ
Sbjct: 239 GGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQ 282


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  184 bits (468), Expect = 6e-47
 Identities = 102/255 (40%), Positives = 141/255 (55%), Gaps = 15/255 (5%)

Query: 27  ACGQPR-MSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALP 85
           ACG  R  SSRIVGG      +WPWQAS+Q +G H+CGGS+I P W++TAAHC     LP
Sbjct: 206 ACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLP 265

Query: 86  AEYRVRLGALRL-GSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQP 144
             + +++G + L  + +P  L   V +++    Y       D+AL++L  P+  +  +QP
Sbjct: 266 KSWTIQVGLVSLLDNPAPSHL---VEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQP 322

Query: 145 VCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRP-LQGVRVPLLDSRTCDGLYHVGADV 203
           VCLP      P G  C  +GWG+   G    +  P L    VPL+ ++ C+     G   
Sbjct: 323 VCLPNSEENFPDGKVCWTSGWGATEDGAG--DASPVLNHAAVPLISNKICNHRDVYGG-- 378

Query: 204 PQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGV 263
                I+ P  LCAGY  G  D+CQGDSGGPL C +   W LVG  S+G GCA  N+PGV
Sbjct: 379 -----IISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGV 433

Query: 264 YTSVATYSPWIQARV 278
           YT V ++  WI  ++
Sbjct: 434 YTRVTSFLDWIHEQM 448


>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
           sapiens]
          Length = 432

 Score =  183 bits (464), Expect = 2e-46
 Identities = 103/248 (41%), Positives = 136/248 (54%), Gaps = 13/248 (5%)

Query: 27  ACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPA 86
           ACG+   + R+VGG +     WPWQ SIQ+   HVCGGS++ P WVLTAAHCF +     
Sbjct: 190 ACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVF 249

Query: 87  EYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVC 146
            ++VR G+ +LGS  P      +  +   P Y +D    D+AL++L+ P+  S  V+P+C
Sbjct: 250 NWKVRAGSDKLGS-FPSLAVAKIIIIEFNPMYPKD---NDIALMKLQFPLTFSGTVRPIC 305

Query: 147 LPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQA 206
           LP       P TP  + GWG  +          LQ   V ++DS  C+       D  Q 
Sbjct: 306 LPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQ-ASVQVIDSTRCN-----ADDAYQG 359

Query: 207 ERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTS 266
           E  V    +CAG P+G  D CQGDSGGPL   QS  W +VG+VSWG GC  P+ PGVYT 
Sbjct: 360 E--VTEKMMCAGIPEGGVDTCQGDSGGPL-MYQSDQWHVVGIVSWGYGCGGPSTPGVYTK 416

Query: 267 VATYSPWI 274
           V+ Y  WI
Sbjct: 417 VSAYLNWI 424


>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
           sapiens]
          Length = 437

 Score =  183 bits (464), Expect = 2e-46
 Identities = 103/248 (41%), Positives = 136/248 (54%), Gaps = 13/248 (5%)

Query: 27  ACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPA 86
           ACG+   + R+VGG +     WPWQ SIQ+   HVCGGS++ P WVLTAAHCF +     
Sbjct: 195 ACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVF 254

Query: 87  EYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVC 146
            ++VR G+ +LGS  P      +  +   P Y +D    D+AL++L+ P+  S  V+P+C
Sbjct: 255 NWKVRAGSDKLGS-FPSLAVAKIIIIEFNPMYPKD---NDIALMKLQFPLTFSGTVRPIC 310

Query: 147 LPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQA 206
           LP       P TP  + GWG  +          LQ   V ++DS  C+       D  Q 
Sbjct: 311 LPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQ-ASVQVIDSTRCN-----ADDAYQG 364

Query: 207 ERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTS 266
           E  V    +CAG P+G  D CQGDSGGPL   QS  W +VG+VSWG GC  P+ PGVYT 
Sbjct: 365 E--VTEKMMCAGIPEGGVDTCQGDSGGPL-MYQSDQWHVVGIVSWGYGCGGPSTPGVYTK 421

Query: 267 VATYSPWI 274
           V+ Y  WI
Sbjct: 422 VSAYLNWI 429


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  182 bits (463), Expect = 2e-46
 Identities = 100/242 (41%), Positives = 136/242 (56%), Gaps = 16/242 (6%)

Query: 36  RIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGAL 95
           RI+GG +  +G WPWQ S++   AH CGGSLI   W+LTAAHCF   + P ++    G  
Sbjct: 186 RILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSG-- 243

Query: 96  RLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPP 155
            + +T P+ L + VR +L+  +Y       D+AL++L   V  +  +  VCLP      P
Sbjct: 244 -ISTTFPK-LRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIP 301

Query: 156 PGTPCRVTGWGSLR-PGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGS 214
           PG+   VTGWG+    G  +PE R  QG +V ++ +  C+  +            +L G 
Sbjct: 302 PGSTAYVTGWGAQEYAGHTVPELR--QG-QVRIISNDVCNAPHSYNG-------AILSGM 351

Query: 215 LCAGYPQGHKDACQGDSGGPLTCLQSGS-WVLVGVVSWGKGCALPNRPGVYTSVATYSPW 273
           LCAG PQG  DACQGDSGGPL    S   W +VG+VSWG  C LP++PGVYT V  Y  W
Sbjct: 352 LCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDW 411

Query: 274 IQ 275
           I+
Sbjct: 412 IR 413


>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
          Length = 438

 Score =  181 bits (460), Expect = 5e-46
 Identities = 102/246 (41%), Positives = 142/246 (57%), Gaps = 15/246 (6%)

Query: 34  SSRIVGGRD-GRDGEWPWQASIQHRGA-HVCGGSLIAPQWVLTAAHCFPRRALPAEYRVR 91
           + RIV GR+   +GEWPWQAS+Q  G+ H CG SLI+  W+LTAAHCF +   P ++   
Sbjct: 203 TQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIAT 262

Query: 92  LGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPG 151
            GA    + +P  +   VR+++L  +Y  +    D+AL+QL   V  S  VQ VCLP   
Sbjct: 263 FGA----TITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSS 318

Query: 152 ARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVL 211
            + PP T   VTG+GS+    P+     L+  RV  + +  C+       DV   + ++ 
Sbjct: 319 IKLPPKTSVFVTGFGSIVDDGPIQN--TLRQARVETISTDVCNR-----KDV--YDGLIT 369

Query: 212 PGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYS 271
           PG LCAG+ +G  DAC+GDSGGPL       W +VG+VSWG+ CALP +PGVYT V  Y 
Sbjct: 370 PGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYR 429

Query: 272 PWIQAR 277
            WI ++
Sbjct: 430 DWIASK 435


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  181 bits (460), Expect = 5e-46
 Identities = 99/254 (38%), Positives = 141/254 (55%), Gaps = 15/254 (5%)

Query: 28  CGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCF--PRRALP 85
           CG   M+ RIVGG    D +WPWQ S+     H+CGG+LI  QWVLTAAHCF   R  + 
Sbjct: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376

Query: 86  AEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPV 145
             ++V  G   L    P   S+    +++  +Y+++    D+AL++L +P+ LSA + P 
Sbjct: 377 EGWKVYAGTSNLHQL-PEAASIA--EIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPA 433

Query: 146 CLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRP-LQGVRVPLLDSRTCDGLYHVGADVP 204
           CLP+ G        C +TG+G  R      +  P L+ V+V L+D + C+       D  
Sbjct: 434 CLPMHGQTFSLNETCWITGFGKTRETDD--KTSPFLREVQVNLIDFKKCN-------DYL 484

Query: 205 QAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVY 264
             +  + P  +CAG  +G +D+CQGDSGGPL C Q+  W L GV SWG GC   N+PGVY
Sbjct: 485 VYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVY 544

Query: 265 TSVATYSPWIQARV 278
           T V    PWI +++
Sbjct: 545 TKVTEVLPWIYSKM 558


>gi|34098976 marapsin 2 [Homo sapiens]
          Length = 326

 Score =  181 bits (458), Expect = 8e-46
 Identities = 111/289 (38%), Positives = 150/289 (51%), Gaps = 29/289 (10%)

Query: 3   GVSCLQVLLLLVLGAA--------------GTQGRKSAACGQPRMSSRIVGGRDGRDGEW 48
           G S L +LLLL++ A               G     S ACG+P M  +I+GG    + +W
Sbjct: 12  GPSALGLLLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPERKW 71

Query: 49  PWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVP 108
           PWQ S+ + G HVCGGS++   WVL+AAHCF R      Y + +G + L      T    
Sbjct: 72  PWQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYE 131

Query: 109 VRRVLLPPDYS-EDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGS 167
           V RV+L P Y       GD+AL+QL+  +  S  V PVCL  P         C  TGWG 
Sbjct: 132 VNRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNLTSAN-CWATGWGL 190

Query: 168 L-RPGVPLPEWRPLQGVRVPLLDSRTCDGLY-HVGADVPQAERIVLPGSLCAGYPQGHKD 225
           + + G    E   LQ +++PL+    C  LY H+          ++P  LCAG     K 
Sbjct: 191 VSKQGETSDE---LQEMQLPLILEPWCHLLYGHMS--------YIMPDMLCAGDILNAKT 239

Query: 226 ACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWI 274
            C+GDSGGPL C  + SW+ +G+VSWG+GC+ P  PGVY SV+ +S WI
Sbjct: 240 VCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWI 288


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score =  180 bits (456), Expect = 1e-45
 Identities = 95/252 (37%), Positives = 136/252 (53%), Gaps = 14/252 (5%)

Query: 27  ACG---QPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRA 83
           ACG        SRIVGG     G WPWQ S+  +  HVCGGS+I P+W++TAAHC  +  
Sbjct: 280 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPL 339

Query: 84  L-PAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARV 142
             P  +    G LR  S         V +V+  P+Y       D+AL++L++P+  +  V
Sbjct: 340 NNPWHWTAFAGILRQ-SFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLV 398

Query: 143 QPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGAD 202
           +PVCLP PG    P   C ++GWG+        E   L   +V L++++ C+  Y     
Sbjct: 399 KPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIETQRCNSRYVY--- 453

Query: 203 VPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPG 262
               + ++ P  +CAG+ QG+ D+CQGDSGGPL   ++  W L+G  SWG GCA   RPG
Sbjct: 454 ----DNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPG 509

Query: 263 VYTSVATYSPWI 274
           VY +V  ++ WI
Sbjct: 510 VYGNVMVFTDWI 521


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score =  180 bits (456), Expect = 1e-45
 Identities = 95/252 (37%), Positives = 136/252 (53%), Gaps = 14/252 (5%)

Query: 27  ACG---QPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRA 83
           ACG        SRIVGG     G WPWQ S+  +  HVCGGS+I P+W++TAAHC  +  
Sbjct: 243 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPL 302

Query: 84  L-PAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARV 142
             P  +    G LR  S         V +V+  P+Y       D+AL++L++P+  +  V
Sbjct: 303 NNPWHWTAFAGILRQ-SFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLV 361

Query: 143 QPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGAD 202
           +PVCLP PG    P   C ++GWG+        E   L   +V L++++ C+  Y     
Sbjct: 362 KPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIETQRCNSRYVY--- 416

Query: 203 VPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPG 262
               + ++ P  +CAG+ QG+ D+CQGDSGGPL   ++  W L+G  SWG GCA   RPG
Sbjct: 417 ----DNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPG 472

Query: 263 VYTSVATYSPWI 274
           VY +V  ++ WI
Sbjct: 473 VYGNVMVFTDWI 484


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score =  177 bits (448), Expect = 1e-44
 Identities = 97/274 (35%), Positives = 149/274 (54%), Gaps = 17/274 (6%)

Query: 6    CLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGS 65
            CLQ  L+ +     + G+K AA     ++ +IVGG + ++G WPW   + + G  +CG S
Sbjct: 757  CLQDSLIRLQCNHKSCGKKLAA---QDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGAS 813

Query: 66   LIAPQWVLTAAHC-FPRRALPAEYRVRLGA-LRLGSTSPRTLSVPVRRVLLPPDYSEDGA 123
            L++  W+++AAHC + R   P+++   LG  ++   TSP+T+   +  +++ P Y+    
Sbjct: 814  LVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRK 873

Query: 124  RGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSL-RPGVPLPEWRPLQG 182
              D+A++ L   V  +  +QP+CLP      PPG  C + GWG++   G        LQ 
Sbjct: 874  DNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTA---NILQE 930

Query: 183  VRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGS 242
              VPLL +  C             E  +    +CAGY +G  D+CQGDSGGPL C ++  
Sbjct: 931  ADVPLLSNERCQQ--------QMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNR 982

Query: 243  WVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQA 276
            W L GV S+G  CALPNRPGVY  V+ ++ WIQ+
Sbjct: 983  WFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQS 1016


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  176 bits (445), Expect = 3e-44
 Identities = 98/248 (39%), Positives = 129/248 (52%), Gaps = 17/248 (6%)

Query: 32  RMSSRIVGGRDGRDGEWPWQASIQHRGA---HVCGGSLIAPQWVLTAAHCFPRRALPAEY 88
           ++  RIVGG     GEWPWQ ++        H+CGGS+I  QW+LTAAHCF     P   
Sbjct: 383 KIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKIL 442

Query: 89  RVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLP 148
           RV  G L        T    V+ +++   Y    +  D+ALL+L   V  +   +P+CLP
Sbjct: 443 RVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLP 502

Query: 149 VPGARPPPGTPCRVTGWG--SLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQA 206
             G R    T C VTGWG   LR  +       LQ  ++PL+ +  C   Y         
Sbjct: 503 SKGDRNVIYTDCWVTGWGYRKLRDKIQ----NTLQKAKIPLVTNEECQKRYR-------- 550

Query: 207 ERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTS 266
              +    +CAGY +G KDAC+GDSGGPL+C  +  W LVG+ SWG+GCA   RPGVYT+
Sbjct: 551 GHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTN 610

Query: 267 VATYSPWI 274
           V  Y  WI
Sbjct: 611 VVEYVDWI 618


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.140    0.468 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,836,095
Number of Sequences: 37866
Number of extensions: 815229
Number of successful extensions: 3625
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 188
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 2840
Number of HSP's gapped (non-prelim): 369
length of query: 280
length of database: 18,247,518
effective HSP length: 101
effective length of query: 179
effective length of database: 14,423,052
effective search space: 2581726308
effective search space used: 2581726308
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.