Search of human proteins with 117938746

Search of human proteins with 117938746

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117938746 constitutive androstane receptor isoform 7 [Homo
sapiens]
         (339 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117938746 constitutive androstane receptor isoform 7 [Homo sa...   696   0.0  
gi|117938729 constitutive androstane receptor isoform 6 [Homo sa...   676   0.0  
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa...   630   0.0  
gi|117938756 constitutive androstane receptor isoform 1 [Homo sa...   624   e-179
gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi...   616   e-177
gi|117938738 constitutive androstane receptor isoform 12 [Homo s...   613   e-176
gi|117938748 constitutive androstane receptor isoform 14 [Homo s...   606   e-173
gi|117938744 constitutive androstane receptor isoform 13 [Homo s...   600   e-172
gi|117938740 constitutive androstane receptor isoform 8 [Homo sa...   591   e-169
gi|117938750 constitutive androstane receptor isoform 10 [Homo s...   540   e-154
gi|117938736 constitutive androstane receptor isoform 9 [Homo sa...   533   e-152
gi|117938754 constitutive androstane receptor isoform 4 [Homo sa...   527   e-150
gi|117938734 constitutive androstane receptor isoform 5 [Homo sa...   525   e-149
gi|117938742 constitutive androstane receptor isoform 15 [Homo s...   514   e-146
gi|117938732 constitutive androstane receptor isoform 11 [Homo s...   448   e-126
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof...   269   2e-72
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof...   258   7e-69
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof...   258   7e-69
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso...   168   6e-42
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso...   168   6e-42
gi|189491771 thyroid hormone receptor, beta [Homo sapiens]            159   3e-39
gi|189491769 thyroid hormone receptor, beta [Homo sapiens]            159   3e-39
gi|40806162 thyroid hormone receptor, beta [Homo sapiens]             159   3e-39
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi...   151   9e-37
gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo sapi...   151   9e-37
gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo...   150   2e-36
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]   144   1e-34
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]     144   1e-34
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]   141   7e-34
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]    141   7e-34

>gi|117938746 constitutive androstane receptor isoform 7 [Homo
           sapiens]
          Length = 339

 Score =  696 bits (1796), Expect = 0.0
 Identities = 339/339 (100%), Positives = 339/339 (100%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300

Query: 301 KGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 339
           KGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ
Sbjct: 301 KGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 339


>gi|117938729 constitutive androstane receptor isoform 6 [Homo
           sapiens]
          Length = 340

 Score =  676 bits (1745), Expect = 0.0
 Identities = 335/344 (97%), Positives = 335/344 (97%), Gaps = 9/344 (2%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR    VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALT 295
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     DRPGVTQRDEIDQLQEEMALT
Sbjct: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 296

Query: 296 LQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 339
           LQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ
Sbjct: 297 LQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 340


>gi|117938752 constitutive androstane receptor isoform 2 [Homo
           sapiens]
          Length = 352

 Score =  630 bits (1624), Expect = 0.0
 Identities = 310/310 (100%), Positives = 310/310 (100%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300

Query: 301 KGQQRRPRDR 310
           KGQQRRPRDR
Sbjct: 301 KGQQRRPRDR 310


>gi|117938756 constitutive androstane receptor isoform 1 [Homo
           sapiens]
          Length = 357

 Score =  624 bits (1608), Expect = e-179
 Identities = 310/315 (98%), Positives = 310/315 (98%), Gaps = 5/315 (1%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALT 295
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     DRPGVTQRDEIDQLQEEMALT
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300

Query: 296 LQSYIKGQQRRPRDR 310
           LQSYIKGQQRRPRDR
Sbjct: 301 LQSYIKGQQRRPRDR 315


>gi|4826661 constitutive androstane receptor isoform 3 [Homo
           sapiens]
          Length = 348

 Score =  616 bits (1589), Expect = e-177
 Identities = 306/310 (98%), Positives = 306/310 (98%), Gaps = 4/310 (1%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR    VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 296

Query: 301 KGQQRRPRDR 310
           KGQQRRPRDR
Sbjct: 297 KGQQRRPRDR 306


>gi|117938738 constitutive androstane receptor isoform 12 [Homo
           sapiens]
          Length = 315

 Score =  613 bits (1581), Expect = e-176
 Identities = 304/309 (98%), Positives = 304/309 (98%), Gaps = 5/309 (1%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 274
           NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP 
Sbjct: 187 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 246

Query: 275 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGP 330
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGP
Sbjct: 247 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGP 306

Query: 331 GSKGAQWLQ 339
           GSKGAQWLQ
Sbjct: 307 GSKGAQWLQ 315


>gi|117938748 constitutive androstane receptor isoform 14 [Homo
           sapiens]
          Length = 306

 Score =  606 bits (1562), Expect = e-173
 Identities = 300/304 (98%), Positives = 300/304 (98%), Gaps = 4/304 (1%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 242

Query: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA 335
           RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA
Sbjct: 243 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA 302

Query: 336 QWLQ 339
           QWLQ
Sbjct: 303 QWLQ 306


>gi|117938744 constitutive androstane receptor isoform 13 [Homo
           sapiens]
          Length = 311

 Score =  600 bits (1546), Expect = e-172
 Identities = 300/309 (97%), Positives = 300/309 (97%), Gaps = 9/309 (2%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 274
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP 
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 242

Query: 275 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGP 330
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGP
Sbjct: 243 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGP 302

Query: 331 GSKGAQWLQ 339
           GSKGAQWLQ
Sbjct: 303 GSKGAQWLQ 311


>gi|117938740 constitutive androstane receptor isoform 8 [Homo
           sapiens]
          Length = 296

 Score =  591 bits (1524), Expect = e-169
 Identities = 296/339 (87%), Positives = 296/339 (87%), Gaps = 43/339 (12%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
                                             DRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 232 ----------------------------------DRPGVTQRDEIDQLQEEMALTLQSYI 257

Query: 301 KGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 339
           KGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ
Sbjct: 258 KGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 296


>gi|117938750 constitutive androstane receptor isoform 10 [Homo
           sapiens]
          Length = 319

 Score =  540 bits (1390), Expect = e-154
 Identities = 271/275 (98%), Positives = 271/275 (98%), Gaps = 4/275 (1%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 242

Query: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310
           RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 243 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277


>gi|117938736 constitutive androstane receptor isoform 9 [Homo
           sapiens]
          Length = 324

 Score =  533 bits (1374), Expect = e-152
 Identities = 271/280 (96%), Positives = 271/280 (96%), Gaps = 9/280 (3%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 274
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP 
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 242

Query: 275 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 243 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282


>gi|117938754 constitutive androstane receptor isoform 4 [Homo
           sapiens]
          Length = 314

 Score =  527 bits (1358), Expect = e-150
 Identities = 268/310 (86%), Positives = 269/310 (86%), Gaps = 38/310 (12%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
                                        A +  DRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 232 -----------------------------APYLTDRPGVTQRDEIDQLQEEMALTLQSYI 262

Query: 301 KGQQRRPRDR 310
           KGQQRRPRDR
Sbjct: 263 KGQQRRPRDR 272


>gi|117938734 constitutive androstane receptor isoform 5 [Homo
           sapiens]
          Length = 309

 Score =  525 bits (1352), Expect = e-149
 Identities = 267/310 (86%), Positives = 267/310 (86%), Gaps = 43/310 (13%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
                                             DRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 232 ----------------------------------DRPGVTQRDEIDQLQEEMALTLQSYI 257

Query: 301 KGQQRRPRDR 310
           KGQQRRPRDR
Sbjct: 258 KGQQRRPRDR 267


>gi|117938742 constitutive androstane receptor isoform 15 [Homo
           sapiens]
          Length = 267

 Score =  514 bits (1325), Expect = e-146
 Identities = 261/304 (85%), Positives = 261/304 (85%), Gaps = 43/304 (14%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275
           NFLCGPLRYTIEDGAR                                           D
Sbjct: 187 NFLCGPLRYTIEDGAR-------------------------------------------D 203

Query: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA 335
           RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA
Sbjct: 204 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA 263

Query: 336 QWLQ 339
           QWLQ
Sbjct: 264 QWLQ 267


>gi|117938732 constitutive androstane receptor isoform 11 [Homo
           sapiens]
          Length = 280

 Score =  448 bits (1153), Expect = e-126
 Identities = 232/275 (84%), Positives = 232/275 (84%), Gaps = 43/275 (15%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275
           NFLCGPLRYTIEDGAR                                           D
Sbjct: 187 NFLCGPLRYTIEDGAR-------------------------------------------D 203

Query: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310
           RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 204 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238


>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
           3 [Homo sapiens]
          Length = 397

 Score =  269 bits (688), Expect = 2e-72
 Identities = 145/315 (46%), Positives = 197/315 (62%), Gaps = 20/315 (6%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 41  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQPLPTLAP--------VLPLVTHFADINTFMVLQVIKF 175
              T F  F  FR    L      +    P        +  L+ H AD++T+M   +I F
Sbjct: 161 TFDTTFSHFKNFRVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISF 220

Query: 176 TKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPT 235
            K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L Y +ED A     
Sbjct: 221 AKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAG---- 276

Query: 236 VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALT 295
            GFQ   LE +  FH  L+KLQL E EYVL+ A++LFSPDRPGV Q   +DQLQE+ A+T
Sbjct: 277 -GFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAIT 335

Query: 296 LQSYIKGQQRRPRDR 310
           L+SYI+  + +P  R
Sbjct: 336 LKSYIECNRPQPAHR 350


>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
           2 [Homo sapiens]
          Length = 473

 Score =  258 bits (658), Expect = 7e-69
 Identities = 148/352 (42%), Positives = 200/352 (56%), Gaps = 57/352 (16%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 80  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 139

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 140 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 199

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
              T F  F  FR P  L    + P    AP                             
Sbjct: 200 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 259

Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
                          +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA
Sbjct: 260 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 319

Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQL 258
            E+C +  NT F  +T  + CG L Y +ED A      GFQ   LE +  FH  L+KLQL
Sbjct: 320 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-----GFQQLLLEPMLKFHYMLKKLQL 374

Query: 259 QEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310
            E EYVL+ A++LFSPDRPGV Q   +DQLQE+ A+TL+SYI+  + +P  R
Sbjct: 375 HEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHR 426


>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
           1 [Homo sapiens]
          Length = 434

 Score =  258 bits (658), Expect = 7e-69
 Identities = 148/352 (42%), Positives = 200/352 (56%), Gaps = 57/352 (16%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 41  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
              T F  F  FR P  L    + P    AP                             
Sbjct: 161 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 220

Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
                          +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA
Sbjct: 221 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 280

Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQL 258
            E+C +  NT F  +T  + CG L Y +ED A      GFQ   LE +  FH  L+KLQL
Sbjct: 281 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-----GFQQLLLEPMLKFHYMLKKLQL 335

Query: 259 QEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310
            E EYVL+ A++LFSPDRPGV Q   +DQLQE+ A+TL+SYI+  + +P  R
Sbjct: 336 HEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHR 387


>gi|194294519 nuclear receptor subfamily 1, group H, member 3
           isoform c [Homo sapiens]
          Length = 402

 Score =  168 bits (426), Expect = 6e-42
 Identities = 106/315 (33%), Positives = 160/315 (50%), Gaps = 26/315 (8%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VCGD+A+G+H+N L+CEGCKGFFRR+V K     C   G C +    RR C  CRL+K
Sbjct: 53  CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 112

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
           C  AGMR++ +LS E + L++ K+ +           RA   P    QLS EQ  +I  L
Sbjct: 113 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 172

Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
           + A  +     F   ++  P P     H +             HF ++    V +++ F 
Sbjct: 173 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 227

Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVSPT 235
           K LP F  L  EDQI+LLK +A+E+  +  +  +   +++        Y  ED A+    
Sbjct: 228 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAK---- 283

Query: 236 VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALT 295
            G QVEF+  +F F   + +LQL + E+ LL A+++FS DRP V  + ++++LQ      
Sbjct: 284 AGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEA 343

Query: 296 LQSYIKGQQRRPRDR 310
           L +Y+      P DR
Sbjct: 344 LHAYV--SIHHPHDR 356


>gi|194294517 nuclear receptor subfamily 1, group H, member 3
           isoform a [Homo sapiens]
          Length = 447

 Score =  168 bits (426), Expect = 6e-42
 Identities = 106/315 (33%), Positives = 160/315 (50%), Gaps = 26/315 (8%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VCGD+A+G+H+N L+CEGCKGFFRR+V K     C   G C +    RR C  CRL+K
Sbjct: 98  CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 157

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
           C  AGMR++ +LS E + L++ K+ +           RA   P    QLS EQ  +I  L
Sbjct: 158 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 217

Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
           + A  +     F   ++  P P     H +             HF ++    V +++ F 
Sbjct: 218 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 272

Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVSPT 235
           K LP F  L  EDQI+LLK +A+E+  +  +  +   +++        Y  ED A+    
Sbjct: 273 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAK---- 328

Query: 236 VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALT 295
            G QVEF+  +F F   + +LQL + E+ LL A+++FS DRP V  + ++++LQ      
Sbjct: 329 AGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEA 388

Query: 296 LQSYIKGQQRRPRDR 310
           L +Y+      P DR
Sbjct: 389 LHAYV--SIHHPHDR 401


>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  159 bits (403), Expect = 3e-39
 Identities = 108/316 (34%), Positives = 158/316 (50%), Gaps = 31/316 (9%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDE 284
           T     R     G      + +F    +L    L + E  LL A+ L S DRPG+   + 
Sbjct: 337 T-----RGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVER 391

Query: 285 IDQLQEEMALTLQSYI 300
           I++ Q+   L  + YI
Sbjct: 392 IEKYQDSFLLAFEHYI 407


>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  159 bits (403), Expect = 3e-39
 Identities = 108/316 (34%), Positives = 158/316 (50%), Gaps = 31/316 (9%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDE 284
           T     R     G      + +F    +L    L + E  LL A+ L S DRPG+   + 
Sbjct: 337 T-----RGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVER 391

Query: 285 IDQLQEEMALTLQSYI 300
           I++ Q+   L  + YI
Sbjct: 392 IEKYQDSFLLAFEHYI 407


>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  159 bits (403), Expect = 3e-39
 Identities = 108/316 (34%), Positives = 158/316 (50%), Gaps = 31/316 (9%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDE 284
           T     R     G      + +F    +L    L + E  LL A+ L S DRPG+   + 
Sbjct: 337 T-----RGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVER 391

Query: 285 IDQLQEEMALTLQSYI 300
           I++ Q+   L  + YI
Sbjct: 392 IEKYQDSFLLAFEHYI 407


>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
           sapiens]
          Length = 410

 Score =  151 bits (381), Expect = 9e-37
 Identities = 104/317 (32%), Positives = 155/317 (48%), Gaps = 33/317 (10%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPT--CPFAGSCEVSKTQRRHC 63
           D+   CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ PT  C +   C + K  R  C
Sbjct: 48  DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107

Query: 64  PACRLQKCLDAGMRKDMILS----------AEALALRRAKQAQRRAQQTPVQLSKEQEEL 113
             CR +KC+  GM  D++L            E    RR K+   R+ Q   + + E+ +L
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDL 167

Query: 114 IRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAP----VLPLVTHFADINTF 167
           I     AH  T   G+ ++Q  +F P     I   P+ ++       L   + F  I T 
Sbjct: 168 IHIATEAHRSTNAQGSHWKQRRKFLPDD---IGQSPIVSMPDGDKVDLEAFSEFTKIITP 224

Query: 168 MVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPL---R 223
            + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  ++    L G +   R
Sbjct: 225 AITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKR 284

Query: 224 YTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRD 283
             +++G       G  V   + +F    +L    L + E  LL A+ L S DR G+   D
Sbjct: 285 EQLKNG-------GLGV-VSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVD 336

Query: 284 EIDQLQEEMALTLQSYI 300
           +I++ QE   L  + Y+
Sbjct: 337 KIEKSQEAYLLAFEHYV 353


>gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo
           sapiens]
          Length = 490

 Score =  151 bits (381), Expect = 9e-37
 Identities = 104/317 (32%), Positives = 155/317 (48%), Gaps = 33/317 (10%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPT--CPFAGSCEVSKTQRRHC 63
           D+   CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ PT  C +   C + K  R  C
Sbjct: 48  DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107

Query: 64  PACRLQKCLDAGMRKDMILS----------AEALALRRAKQAQRRAQQTPVQLSKEQEEL 113
             CR +KC+  GM  D++L            E    RR K+   R+ Q   + + E+ +L
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDL 167

Query: 114 IRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAP----VLPLVTHFADINTF 167
           I     AH  T   G+ ++Q  +F P     I   P+ ++       L   + F  I T 
Sbjct: 168 IHIATEAHRSTNAQGSHWKQRRKFLPDD---IGQSPIVSMPDGDKVDLEAFSEFTKIITP 224

Query: 168 MVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPL---R 223
            + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  ++    L G +   R
Sbjct: 225 AITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKR 284

Query: 224 YTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRD 283
             +++G       G  V   + +F    +L    L + E  LL A+ L S DR G+   D
Sbjct: 285 EQLKNG-------GLGV-VSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVD 336

Query: 284 EIDQLQEEMALTLQSYI 300
           +I++ QE   L  + Y+
Sbjct: 337 KIEKSQEAYLLAFEHYV 353


>gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo
           sapiens]
          Length = 472

 Score =  150 bits (378), Expect = 2e-36
 Identities = 100/312 (32%), Positives = 161/312 (51%), Gaps = 25/312 (8%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPA 65
           DEL  CVVCGD+A+GYH+NALTCEGCKGFFRR+++K+    C   G+C +    RR C  
Sbjct: 124 DEL--CVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQE 181

Query: 66  CRLQKCLDAGMRKDMILS-AEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRH 124
           CRL+KC + GM  + +L+  +  + R  K  ++ A QT   ++++ E      + + T+ 
Sbjct: 182 CRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQT---VNEDSEGRDLRQVTSTTKS 238

Query: 125 MGTMFEQFVQFRPPAHLFI---HHQPLPTLAPVLPLVTHFADINTFMVLQ---------V 172
                E     +   H  +   + Q +P       L   F+    F++L          +
Sbjct: 239 CREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVL 298

Query: 173 IKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARV 232
           ++FTK LP F++L  EDQI+LLKG+AVE   +     F  +  +     L   I +    
Sbjct: 299 VEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNS--- 355

Query: 233 SPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEM 292
               G   E++  +F F+ ++ +L++ + EY LL A+ + SPDR  +  R+ +++LQE +
Sbjct: 356 ----GISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPL 411

Query: 293 ALTLQSYIKGQQ 304
              LQ   K  Q
Sbjct: 412 LDVLQKLCKIHQ 423


>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
          Length = 443

 Score =  144 bits (363), Expect = 1e-34
 Identities = 91/300 (30%), Positives = 151/300 (50%), Gaps = 22/300 (7%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+   +CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 79  CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 138

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+ +        +LS + EELI  +  AH        E
Sbjct: 139 CFEVGMSKEAVRNDRN---KKKKEVKEEGSPDSYELSPQLEELITKVSKAHQ-------E 188

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           +      +   L L   F+++ T  ++++++F K LP F  L I DQ
Sbjct: 189 TFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQ 248

Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
           I+LLK A ++I  + + T +  +           T  DG  ++ T      F    +L+F
Sbjct: 249 ITLLKAACLDILMLRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 301

Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 307
            F G L  L++ + E  LL+A+ L   DR  + + +++D+LQE +   L+ Y   ++RRP
Sbjct: 302 AFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLY--ARRRRP 359


>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
          Length = 454

 Score =  144 bits (363), Expect = 1e-34
 Identities = 91/300 (30%), Positives = 151/300 (50%), Gaps = 22/300 (7%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+   +CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 90  CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 149

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+ +        +LS + EELI  +  AH        E
Sbjct: 150 CFEVGMSKEAVRNDRN---KKKKEVKEEGSPDSYELSPQLEELITKVSKAHQ-------E 199

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           +      +   L L   F+++ T  ++++++F K LP F  L I DQ
Sbjct: 200 TFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQ 259

Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
           I+LLK A ++I  + + T +  +           T  DG  ++ T      F    +L+F
Sbjct: 260 ITLLKAACLDILMLRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 312

Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 307
            F G L  L++ + E  LL+A+ L   DR  + + +++D+LQE +   L+ Y   ++RRP
Sbjct: 313 AFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLY--ARRRRP 370


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  141 bits (356), Expect = 7e-34
 Identities = 90/300 (30%), Positives = 149/300 (49%), Gaps = 22/300 (7%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+    CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 88  CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 147

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+  +        L+ E  ELI  +  AH        E
Sbjct: 148 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 197

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           ++     ++  + L   F++++T  +++ ++F K LP F +L I DQ
Sbjct: 198 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 257

Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
           I+LLK A ++I  + + T +  +           T  DG  ++ T      F    +L+F
Sbjct: 258 ITLLKAACLDILILRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 310

Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 307
            F   L  L++ + E  LL+A+ L   DR  + Q D +D LQE +   L+ Y++  +RRP
Sbjct: 311 AFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRP 368


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score =  141 bits (356), Expect = 7e-34
 Identities = 90/300 (30%), Positives = 149/300 (49%), Gaps = 22/300 (7%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+    CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 83  CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 142

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+  +        L+ E  ELI  +  AH        E
Sbjct: 143 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 192

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           ++     ++  + L   F++++T  +++ ++F K LP F +L I DQ
Sbjct: 193 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 252

Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
           I+LLK A ++I  + + T +  +           T  DG  ++ T      F    +L+F
Sbjct: 253 ITLLKAACLDILILRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 305

Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 307
            F   L  L++ + E  LL+A+ L   DR  + Q D +D LQE +   L+ Y++  +RRP
Sbjct: 306 AFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRP 363


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,558,591
Number of Sequences: 37866
Number of extensions: 609403
Number of successful extensions: 2564
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2240
Number of HSP's gapped (non-prelim): 203
length of query: 339
length of database: 18,247,518
effective HSP length: 103
effective length of query: 236
effective length of database: 14,347,320
effective search space: 3385967520
effective search space used: 3385967520
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.