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Search of human proteins with 239747134
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
(600 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 1201 0.0
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 267 2e-71
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 232 8e-61
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 228 1e-59
gi|148746195 trichohyalin [Homo sapiens] 219 4e-57
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 208 1e-53
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 206 4e-53
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 184 2e-46
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 175 1e-43
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 175 1e-43
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 171 2e-42
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 170 4e-42
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 167 3e-41
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 166 7e-41
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 163 5e-40
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 162 6e-40
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 158 2e-38
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 149 5e-36
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 148 1e-35
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 148 1e-35
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 144 2e-34
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 144 2e-34
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 143 5e-34
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 141 2e-33
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 134 2e-31
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 133 4e-31
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 130 3e-30
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 129 1e-29
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 128 1e-29
gi|155030242 WD repeat domain 60 [Homo sapiens] 126 5e-29
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 1201 bits (3106), Expect = 0.0
Identities = 600/600 (100%), Positives = 600/600 (100%)
Query: 1 MAKKIVPATADQLGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQK 60
MAKKIVPATADQLGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQK
Sbjct: 1 MAKKIVPATADQLGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQK 60
Query: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKE 120
ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKE
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKE 120
Query: 121 RNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERE 180
RNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERE
Sbjct: 121 RNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERE 180
Query: 181 REKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTER 240
REKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTER
Sbjct: 181 REKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTER 240
Query: 241 EREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERK 300
EREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERK
Sbjct: 241 EREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERK 300
Query: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG
Sbjct: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
Query: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRER 420
REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRER
Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRER 420
Query: 421 EKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSD 480
EKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSD
Sbjct: 421 EKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSD 480
Query: 481 PNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRP 540
PNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRP
Sbjct: 481 PNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRP 540
Query: 541 SGGFGTENPLSQAPSVFPGPRYTPGDGKRNVHTVLSVFVFISFIFSILREMLISTTRRRM 600
SGGFGTENPLSQAPSVFPGPRYTPGDGKRNVHTVLSVFVFISFIFSILREMLISTTRRRM
Sbjct: 541 SGGFGTENPLSQAPSVFPGPRYTPGDGKRNVHTVLSVFVFISFIFSILREMLISTTRRRM 600
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 267 bits (683), Expect = 2e-71
Identities = 138/284 (48%), Positives = 200/284 (70%), Gaps = 32/284 (11%)
Query: 7 PATADQLGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRR 66
P LGTLWVEVTIPLDFSR R GSQESPR GLGQAHKDADGDDR+R ER+R R
Sbjct: 30 PHLHSSLGTLWVEVTIPLDFSRGRLGSQESPRSWGLGQAHKDADGDDRQR----ERDRVR 85
Query: 67 EKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKE 126
EK + ER+ DRKR+R R R +E++ +R ++RE+QT+ ERDR+REK++ R++E
Sbjct: 86 EKTEKERDRDRKRDRER---------RRKEKETNRNRDREKQTEIERDREREKQKGRERE 136
Query: 127 RERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQ 186
R+R G RERER RD EKERERQT+++R Q E ++ER+RE+ +Q
Sbjct: 137 RDR--------G--------RERERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180
Query: 187 ERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA 246
+ RE ER R+++ TE + ER +RER+R+ +T+TER+R+TDRE +R+ T+R RE+Q
Sbjct: 181 KERETERDRDRQRDTE-KERERQTDRERDRQRKTQTERQRETDREGERE--TDRRRERQR 237
Query: 247 ERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
+R+R ER+ ERD++ ER+++R ++R + +KE++++ R+ ++
Sbjct: 238 DRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
Score = 207 bits (527), Expect = 2e-53
Identities = 104/235 (44%), Positives = 168/235 (71%), Gaps = 16/235 (6%)
Query: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Q K+ +DR ER R RE+ TE++R DR+RDR+R+ +E+E R+R +
Sbjct: 67 QAHKDADGDDRQRERDRVREK-------TEKERDRDRKRDRERR-RKEKETNRNRDREKQ 118
Query: 254 RETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERDRETERKRERQRERERERE 312
E ERD+ERE+++ R+R+RDR R++ER+R +++R+R+TE+DR+ +R+ E +RER+RERE
Sbjct: 119 TEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRERE 178
Query: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372
+ ++ERE ER+R+RQR+TE++RE++ +R+R RQ + ER R+T REG R+ +R RE
Sbjct: 179 K----QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRE 234
Query: 373 RERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESE 427
R+R+RDR R +RERDR +R+KER+++ +K+R +++ EK+RE +K + E
Sbjct: 235 RQRDRDRGKER---DRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
Score = 205 bits (522), Expect = 8e-53
Identities = 107/221 (48%), Positives = 162/221 (73%), Gaps = 10/221 (4%)
Query: 144 DGQRERERQRD-AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202
D QRER+R R+ EKER+R R+R+R R ++KE R ++R+++ E ER RE+E K +
Sbjct: 76 DRQRERDRVREKTEKERDRDRKRDRER---RRKEKETNRNRDREKQTEIERDRERE-KQK 131
Query: 203 DRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKER 262
R ER R RERER+ + E ER+RQT+++RD QR+TE ERE+ ERE+ ERETERD++R
Sbjct: 132 GRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDR 191
Query: 263 ERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE 322
+R+ +++R+ RQ +RER DR+R+ +TER RET+R+ ER+ +R RER+R+R R +ER+
Sbjct: 192 QRDTEKERE---RQTDRER--DRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERD 246
Query: 323 RERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363
RER+R+ +R+ ER +E+++ERK K++ E RE ++ EG
Sbjct: 247 RERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 287
Score = 197 bits (500), Expect = 3e-50
Identities = 97/211 (45%), Positives = 160/211 (75%), Gaps = 14/211 (6%)
Query: 253 ERETERDKERER---ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309
+R+ ERD+ RE+ ERDRDR RDR ++ +E++T+R R R E+ E ER RER++++ R
Sbjct: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDR--EKQTEIERDREREKQKGR 133
Query: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER 369
ERER+R RERER+R+RE+ER+R+TE+DR+ +RE TE +RER+R+ RE +++ E
Sbjct: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRE------TETERERDRE--REKQKERET 185
Query: 370 ERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERG 429
ER+R+R+RD + RER + +R+RDR R+ + ERQ E DR+G+RET+++RER++DR+ +
Sbjct: 186 ERDRDRQRDTEKERER-QTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKE 244
Query: 430 RERGREREKQKGRERDRERQTDRQAGRQRKR 460
R+R R+R++++ +ER +ER+ +R+ ++ ++
Sbjct: 245 RDRERDRKEERKKERKKERKKERKEKKKEEK 275
Score = 196 bits (499), Expect = 4e-50
Identities = 95/208 (45%), Positives = 151/208 (72%), Gaps = 4/208 (1%)
Query: 188 RRERERQREKENKTEDRHSERGRERER-ERETETETERKRQTDRERDRQRKTEREREKQA 246
+RER+R REK K DR +R RER R E+ET +R++QT+ ERDR+R+ ++ RE+
Sbjct: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER-- 135
Query: 247 ERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
ER+R ERE +RD+E+ERER ++DRD Q+E E + +R R+R +++RETER R+RQR+
Sbjct: 136 ERDRGRERERDRDREKERERQTEKDRD-GQRETETERERDREREKQKERETERDRDRQRD 194
Query: 307 RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQ 366
E+ERER RER+R+R+ + ERQRET+R+ E+E +R+R+RQ + DR + R R+ + +
Sbjct: 195 TEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEE 254
Query: 367 AERERERERERDRQSAREREERERDRDR 394
++ER++ER+++R+ ++ E+R D+ R
Sbjct: 255 RKKERKKERKKERKEKKKEEKRREDKKR 282
Score = 191 bits (484), Expect = 2e-48
Identities = 90/207 (43%), Positives = 148/207 (71%), Gaps = 2/207 (0%)
Query: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
+R R+++R REK +ER +R+R+R++E + +++ + R R+RE++ E E + ER++Q RE
Sbjct: 76 DRQRERDRVREKTEKER-DRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE 134
Query: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR-RQKERERQTDRKRQRR 290
R+R R ERER++ E+ER + E +RD +RE E +R+RDR+R +QKERE + DR RQR
Sbjct: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
Query: 291 TERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTE 350
TE++RE + RER R+R+ + ER R+ +RE ERE +R R+R+ +RDR KER+R+R R+ E
Sbjct: 195 TEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEE 254
Query: 351 MDRERNRQTGREGRRQAERERERERER 377
+ER ++ +E + + + E+ RE ++
Sbjct: 255 RKKERKKERKKERKEKKKEEKRREDKK 281
Score = 184 bits (468), Expect = 2e-46
Identities = 95/200 (47%), Positives = 142/200 (71%), Gaps = 17/200 (8%)
Query: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER---ERERNRKRERER--- 321
+D D D RQ+ER+R ++ E ER R+R+R+RER E+E NR R+RE+
Sbjct: 70 KDADGDDRQRERDRVREKT---------EKERDRDRKRDRERRRKEKETNRNRDREKQTE 120
Query: 322 -ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQ 380
ER+RERE+Q+ ER+R++ RER+R R E +RER + R+G+R+ E ERER+RER++Q
Sbjct: 121 IERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQ 180
Query: 381 SAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQK 440
RE ER+RDR RD +KERERQT+++RD QR+T+ +R+RE DRE ER +R RER++ +
Sbjct: 181 KERE-TERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239
Query: 441 GRERDRERQTDRQAGRQRKR 460
R ++R+R+ DR+ R+++R
Sbjct: 240 DRGKERDRERDRKEERKKER 259
Score = 169 bits (428), Expect = 7e-42
Identities = 100/239 (41%), Positives = 146/239 (61%), Gaps = 24/239 (10%)
Query: 302 ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR 361
+RQRER+R RE+ K ER+R+R+R+RER+R +++E R R R++QTE++R+R R
Sbjct: 76 DRQRERDRVREKTEK-ERDRDRKRDRERRR---KEKETNRNRDREKQTEIERDRER---- 127
Query: 362 EGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRERE 421
E+++ RERERDR RER+RDRDR+KERERQTEKDRDGQRETE +RER+
Sbjct: 128 ------EKQKGRERERDRG-------RERERDRDREKERERQTEKDRDGQRETETERERD 174
Query: 422 KDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDP 481
++RE ++ RE R+R++Q+ E++RERQTDR+ RQRK T T R G ++D
Sbjct: 175 REREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQT---ERQRETDREGERETDR 231
Query: 482 NRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRP 540
R + R + D + K + +++ E R +K+ + GEG P
Sbjct: 232 RRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGISP 290
Score = 73.6 bits (179), Expect = 5e-13
Identities = 37/109 (33%), Positives = 70/109 (64%), Gaps = 3/109 (2%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK-RQTERETDRKRERRREKD 86
+ R ++ R+R + + +R+R R+ + ER+RE R+ ERETDR+RER ++D
Sbjct: 181 KERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRER--QRD 238
Query: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135
R R ++R RER R E+++ER+ +R+++R+ +K+ +++E ++ EG
Sbjct: 239 RDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 287
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 232 bits (591), Expect = 8e-61
Identities = 129/325 (39%), Positives = 203/325 (62%), Gaps = 10/325 (3%)
Query: 55 ERNRQKERERRR-EKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113
E +KE+ER+ EK + ERE +R+RER R R R+R+R RER+R++EKERER+ +R+R
Sbjct: 293 EEKGKKEKERQEIEKERRERERERERERER---REREREREREREREKEKERERERERDR 349
Query: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
DR R KER+R ++RER+ +R+ ER DR D R RE+ RD E+ERER+ +RER+R+ ER
Sbjct: 350 DRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERER 409
Query: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE-RERETETETERKRQTDRER 232
R++ERERE+ R+ RE++++R++E ED + R ER+ RE+E + K RER
Sbjct: 410 EREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRER 469
Query: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
+ R+ E+E E++ ER R +E +R KE + D DRD + + Q KR R E
Sbjct: 470 KKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQ---KRLRDRE 526
Query: 293 RDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
++ E + +R+R+RE+E E ++ E + + E QR E++ E+ R+ + K++ E +
Sbjct: 527 KEMEAD-ERDRKREKEELEEIRQRLLAEGHPDPDAELQR-MEQEAERRRQPQIKQEPESE 584
Query: 353 RERNRQTGREGRRQAERERERERER 377
E + +E +R+ E E E E+
Sbjct: 585 EEEEEKQEKEEKREEPMEEEEEPEQ 609
Score = 219 bits (558), Expect = 6e-57
Identities = 127/355 (35%), Positives = 215/355 (60%), Gaps = 29/355 (8%)
Query: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143
E+D+ R + RD K+ E + ++ ++E E+ R +ERERE ERE ER
Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER-RERERERERERER------ 322
Query: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203
RERER+R+ E+ERE++ +RER+R+ +R+R + +ER+++R R+R+R RE+ + D
Sbjct: 323 ---REREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSS---D 376
Query: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
R+ +R R RE+ R+ E E ER+R+ +RER+R+R+ ERERE++ ER ERE E+DK+R+
Sbjct: 377 RNKDRSRSREKSRDRERERERERERERERERERERERERERERER----EREREKDKKRD 432
Query: 264 RERDRDRDRDRRQKERE-RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE 322
RE D + +RR+ ER+ R+ + Q R + ERK+ R+ E+E ERE R+RE +E
Sbjct: 433 REEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKE 492
Query: 323 RERERERQRETERDRE----------KERERKRKRQTEMDRERNRQTGREGRRQAERERE 372
+R +E + + DR+ ++R R R+++ E D ER+R+ +E + +
Sbjct: 493 AKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEAD-ERDRKREKEELEEIRQRLL 551
Query: 373 RERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESE 427
E D + +R E+E +R R Q ++E ++E++ + ++E E++RE + E E
Sbjct: 552 AEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEE 606
Score = 217 bits (553), Expect = 2e-56
Identities = 136/337 (40%), Positives = 194/337 (57%), Gaps = 28/337 (8%)
Query: 73 RETDRKRER---RREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERER 129
R+T +K E ++EK+R RER+R+RE+ERER RER+R+RE+ER R+KE+ER
Sbjct: 285 RDTHKKLEEEKGKKEKERQEIEKERRERERERERERER---REREREREREREREKEKER 341
Query: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
E ERE +R RDR + R+R+R+RD +++RER +DR + R R + ++RERE+ R+ R
Sbjct: 342 ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERER 401
Query: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE-RDRQRKTERE-REKQAE 247
ERER+RE+E R ER RERERERE E + +R R+ D E +RK ER+ REK+A
Sbjct: 402 ERERERERE-----REREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAA 456
Query: 248 ----------RERASERETERDKERERERDRDRDRD-RRQKERERQTDRKRQRRTERDRE 296
RER RE E++ ERE ER R+ ++ +R KE D R
Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGS 516
Query: 297 TERKRERQRERERER-ERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER 355
+KR R RE+E E ER+RKRE+E E + E D + E +R + E +R R
Sbjct: 517 ALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQR---MEQEAERRR 573
Query: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDR 392
Q +E + E E ++E+E R+ E EE +
Sbjct: 574 QPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 211 bits (538), Expect = 1e-54
Identities = 143/404 (35%), Positives = 222/404 (54%), Gaps = 46/404 (11%)
Query: 178 EREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRK 237
E E +K RE + R+ K E+ ++ +ER+ + E ER+R+ +RER R+R+
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERER-RERE 326
Query: 238 TEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRET 297
ERERE++ E+E+ ERE ERD++R+R ++RDRDRD RER DR R+R ++R+++
Sbjct: 327 REREREREREKEKERERERERDRDRDRTKERDRDRD-----RERDRDRDRERSSDRNKDR 381
Query: 298 ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR 357
R RE+ R+RERERER R+RERERERERERER+RE ER+RE+ERE+ +KR DRE +
Sbjct: 382 SRSREKSRDREREREREREREREREREREREREREREREREREREKDKKR----DREEDE 437
Query: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
+ E RR+ ER+ + ++ + E RER + R+ +KE ER+ E+ R+ +E ++
Sbjct: 438 EDAYE-RRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRL 496
Query: 418 REREKDRESERG----------RERGREREKQ-KGRERDRERQTDRQAGRQRKRSTLYVN 466
+E +D + +R ++R R+REK+ + ERDR+R+ + + R+R +
Sbjct: 497 KEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKE-ELEEIRQRLLAEGH 555
Query: 467 PPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPR 526
P P + Q R R + K PE + + + +R EP
Sbjct: 556 PDPDAELQRMEQEAERR--RQPQIKQEPESEEEEEEK------------QEKEEKREEPM 601
Query: 527 LGEKRGQGGEGRRPSGGFGTENPLSQAPSVFP----GPRYTPGD 566
E+ + +P T P+S APSV TPGD
Sbjct: 602 EEEEEPEQKPCLKP-----TLRPISSAPSVSSASGNATPNTPGD 640
Score = 204 bits (518), Expect = 2e-52
Identities = 133/381 (34%), Positives = 213/381 (55%), Gaps = 42/381 (11%)
Query: 136 ERGRDRQTDGQRERERQRDAEKERERQT---DRERQRQTERNRQKEREREKNRQERRERE 192
E D++ RE + RD K+ E + ++ERQ + R++ERERE+ R ERRERE
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERER-ERRERE 326
Query: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERAS 252
R+RE+E + E + ER RERER+R+ + ER R DRERDR R +RER ++R+
Sbjct: 327 RERERERERE-KEKERERERERDRDRDRTKERDRDRDRERDRDR--DRERSSDRNKDRSR 383
Query: 253 ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERE 312
RE RD+ERERER+R+R+R+ R++ERER+ +R+R+R ER+RE ++KR+R+ + E E
Sbjct: 384 SREKSRDRERERERERERERE-REREREREREREREREREREREKDKKRDREEDEEDAYE 442
Query: 313 RNRK--------------------RERERERERERERQRETERDREKERERKRKRQTEMD 352
R + RER++ RE E+E +RE ER RE +E KR ++ D
Sbjct: 443 RRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLED 502
Query: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKE------RERQTEK 406
+ +R + R A ++R R+RE++ E +ER+R R+++ +E E +
Sbjct: 503 YDDDRDDPKYYRGSALQKRLRDREKE----MEADERDRKREKEELEEIRQRLLAEGHPDP 558
Query: 407 DRDGQR---ETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
D + QR E E++R+ + +E E E ++EK++ RE E + + + K +
Sbjct: 559 DAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLR 618
Query: 464 YVNPPPRTARSGVVQSDPNRP 484
++ P + S + PN P
Sbjct: 619 PISSAP-SVSSASGNATPNTP 638
Score = 202 bits (515), Expect = 5e-52
Identities = 116/318 (36%), Positives = 194/318 (61%), Gaps = 17/318 (5%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
QE + R + ++ + + RER R++ERER REK E+E +R+RER R++DR ++RDR
Sbjct: 303 QEIEKERRERERERERERERREREREREREREREK---EKERERERERDRDRDRTKERDR 359
Query: 94 HRERQRDREKERERQTDRERDRQR------EKERNRQKERERETEREGERGRDRQTDGQR 147
R+R+RDR+++RER +DR +DR R ++ER R++ERERE ERE ER R+R+ + +R
Sbjct: 360 DRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERER 419
Query: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207
ERER+R+ +K+R+R+ D E + + +K RE+E QER + RE++ KT + E
Sbjct: 420 EREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK-KTREYEKE 478
Query: 208 RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
RE ER RE E +R ++ + D R + A ++R +RE E + + ERD
Sbjct: 479 AEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEAD---ERD 535
Query: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETER-KRERQRERERERERNRKRERERERERE 326
R R+++ ++ R+R + + D E +R ++E +R R+ + ++ + E E E ++E
Sbjct: 536 RKREKEELEEIRQRLL---AEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQE 592
Query: 327 RERQRETERDREKERERK 344
+E +RE + E+E E+K
Sbjct: 593 KEEKREEPMEEEEEPEQK 610
Score = 196 bits (499), Expect = 4e-50
Identities = 111/329 (33%), Positives = 186/329 (56%), Gaps = 8/329 (2%)
Query: 128 ERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQE 187
E + +++ G R + E D E +R Q + R E +
Sbjct: 171 EWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESD 230
Query: 188 RRERERQREKENKTEDRHSERGR------ERERERETETETERKRQTDRERDRQRKTERE 241
R++++EK+ R +E E E +++ RE + R T ++
Sbjct: 231 SHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKK 290
Query: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKR 301
E++ ++ +E E+++ RERER+R+R+R+RR++ERER+ +R+R++ ER+RE ER R
Sbjct: 291 LEEEKGKKEKERQEIEKER-RERERERERERERREREREREREREREKEKERERERERDR 349
Query: 302 ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR 361
+R R +ER+R+R+R+R+R+R+RER +R ++ R REK R+R+R+R+ E +RER R+ R
Sbjct: 350 DRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERER 409
Query: 362 EGRRQAERERERERERDRQSAREREERERDRDRDRQKERE-RQTEKDRDGQRETEKQRER 420
E R+ ERERERERER++ R+REE E D R+ ER+ R+ E + + + RER
Sbjct: 410 EREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRER 469
Query: 421 EKDRESERGRERGREREKQKGRERDRERQ 449
+K RE E+ ER ER ++ +E R ++
Sbjct: 470 KKTREYEKEAEREEERRREMAKEAKRLKE 498
Score = 154 bits (388), Expect = 3e-37
Identities = 98/268 (36%), Positives = 149/268 (55%), Gaps = 44/268 (16%)
Query: 215 ERETETETERKRQTDRERDRQRKTERE---REKQAERERASERETERDKERERERDRDRD 271
E T + E + + RD+ K E RE +E S+ +++++E+ D
Sbjct: 186 ETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIF 245
Query: 272 R----------------DRRQKERERQTDRKRQRRTERDRETERKRERQR-ERERERERN 314
R D E E R + R+T +K E ++ ++E+ER+
Sbjct: 246 RRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEI 305
Query: 315 RKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
K RERERERERER+R RE+ERER+R+R+ E ++ER ERERER+
Sbjct: 306 EKERRERERERERERER-----REREREREREREREKEKER------------ERERERD 348
Query: 375 RERDRQSAREREERERDRD--RDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER 432
R+RDR +ER+RDRD RDR ++RER +++++D R EK R+RE++RE ER RER
Sbjct: 349 RDRDRT-----KERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERER 403
Query: 433 GREREKQKGRERDRERQTDRQAGRQRKR 460
RERE+++ RER+RER+ +R+ + +KR
Sbjct: 404 EREREREREREREREREREREREKDKKR 431
Score = 114 bits (284), Expect = 3e-25
Identities = 81/252 (32%), Positives = 127/252 (50%), Gaps = 28/252 (11%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
D SR R S++ R R +RER R++ERER RE+ ERE +R+RER RE
Sbjct: 380 DRSRSREKSRDRERERER----------ERERERERERERERER---ERERERERERERE 426
Query: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQRE------KERNRQKERERETEREGERG 138
KD+ R R+ E +R K + ++E Q +ER + +E E+E ERE ER
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486
Query: 139 RDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKE 198
R+ + +R +E D + +R+ +R R +E+E E + ER+R+REKE
Sbjct: 487 REMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEAD-----ERDRKREKE 541
Query: 199 NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER 258
E R E + + E +R Q + ER RQ + ++E E + E E E+E +R
Sbjct: 542 ELEEIRQRLLA---EGHPDPDAELQRMEQ-EAERRRQPQIKQEPESEEEEEEKQEKEEKR 597
Query: 259 DKERERERDRDR 270
++ E E + ++
Sbjct: 598 EEPMEEEEEPEQ 609
Score = 40.0 bits (92), Expect = 0.006
Identities = 26/103 (25%), Positives = 50/103 (48%), Gaps = 5/103 (4%)
Query: 36 SPRRRGLGQAHKDADGDDRERNRQKER-ERRREKRQTERETDRKRE-RRREKDRHRKRD- 92
S ++ L K+ + D+R+R R+KE E R++ E D E +R E++ R+R
Sbjct: 516 SALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQP 575
Query: 93 --RHRERQRDREKERERQTDRERDRQREKERNRQKERERETER 133
+ + E+E++ + ++ + E+E QK + T R
Sbjct: 576 QIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLR 618
Score = 38.1 bits (87), Expect = 0.023
Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
+R E R+R L + H D D + + ++ ER R+ + +Q E E++ + E ++EK+
Sbjct: 537 KREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQ-EPESEEEEEEKQEKEE 595
Query: 88 HRKRDRHRERQRDRE 102
R+ E + +++
Sbjct: 596 KREEPMEEEEEPEQK 610
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 228 bits (581), Expect = 1e-59
Identities = 172/539 (31%), Positives = 258/539 (47%), Gaps = 87/539 (16%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKR-QTERETDRKRERRREKDRHRKRD 92
Q PR R + D + ++ + ERR + R + +RE D + ER E+D+ RD
Sbjct: 386 QSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRD 445
Query: 93 RHRERQ-RDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD-------RQTD 144
+R+ RD R+ + R+R R+ R R+ R+ + RD R
Sbjct: 446 HRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAH 505
Query: 145 GQRERE-----RQRDAEKERERQTDRERQRQTE-----RNRQKEREREKNRQERRERERQ 194
R+RE R+ D E R R R+ RN + R + R +R R R
Sbjct: 506 DYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRG 565
Query: 195 REKENKTEDRHSERG------------------------RERERERETETET-------- 222
R E + RG R+R ER+ +
Sbjct: 566 RVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERR 625
Query: 223 --ERKRQTDRERDRQ---------RKTEREREKQAERERASERETERDKERERERDRDRD 271
ER R+ +RERD++ R E ER+++ E ER +R +R ER RERDR+R+
Sbjct: 626 HGERDRRDNRERDQRPSSPIRHQGRNDELERDERRE-ERRVDRVDDRRDERARERDRERE 684
Query: 272 RDR-RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ 330
RDR R++ERER+ DR+R++ E +RE R+RER+RE+ER+RER+R R+ +RERERERER
Sbjct: 685 RDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERD 744
Query: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERER 390
RE ER+RE+E ER+R+R+ E +RER R ERERER RERD++ R+R+ ++
Sbjct: 745 REKERERERE-ERERERERERERERER----------ERERERARERDKERERQRDWEDK 793
Query: 391 DRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQT 450
D+ RD ++E+ + +DR+ R+ +R+ +K R R G +Q + R RE
Sbjct: 794 DKGRDDRREKREEIREDRN-PRDGHDERKSKK-----RYRNEGSPSPRQSPKRR-REHSP 846
Query: 451 DRQA---GRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDP--KAASTRF 504
D A G + ++ R S + R RWK P K +S R+
Sbjct: 847 DSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRY 905
Score = 216 bits (550), Expect = 5e-56
Identities = 153/473 (32%), Positives = 242/473 (51%), Gaps = 58/473 (12%)
Query: 25 DFSRRRPGSQESPRRRGLGQAH--KDADGDDRERNRQKERERRREKRQTERETDRKRERR 82
D+SR S++ R AH +D +G D R E R + + R
Sbjct: 484 DYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEI 543
Query: 83 REKDRHRKRDRHRERQRDREKER-----ERQTDRERDRQREKERNRQKERERETEREGER 137
R + R+ R R + R + R E+ + R Q + + + R
Sbjct: 544 RNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYP 603
Query: 138 GRDRQTD-GQRERERQRDAEK---ERERQTDRER-QRQTERNRQKEREREKNRQERRERE 192
RDR + R++ R E+ ER+R+ +RER QR + R + R E R ERRE
Sbjct: 604 ERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREER 663
Query: 193 R------QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA 246
R +R++ + DR ER RERERERE E + ER+++ + ER+R R+ EREREK+
Sbjct: 664 RVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKER 723
Query: 247 ERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
+RER +R+ +R++ERERERDR+++R+R ++ERE RE ER+RER+RE
Sbjct: 724 DRERDRDRDHDRERERERERDREKEREREREERE--------------RERERERERERE 769
Query: 307 RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQ 366
RERERER R+R++ERER+R+ E D++K R+ +R+++ E+ +RN + G + R+
Sbjct: 770 RERERERARERDKERERQRDWE-------DKDKGRDDRREKREEIREDRNPRDGHDERKS 822
Query: 367 AERERERERERDRQSAREREERERDRDR----DRQKERER---QTEKDRDGQ-------R 412
+R R RQS + R E D D D + E+ R Q + ++ +
Sbjct: 823 KKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLT 882
Query: 413 ETEKQREREKDRESERGRERGREREKQKGRER----DRERQTDRQAGRQRKRS 461
E + R +E+DR+ ER +E R E+Q+ +E+ D++R+ R R+
Sbjct: 883 EDRQGRWKEEDRKPER-KESSRRYEEQELKEKVSSVDKQREQTEILESSRMRA 934
Score = 212 bits (539), Expect = 9e-55
Identities = 133/378 (35%), Positives = 217/378 (57%), Gaps = 17/378 (4%)
Query: 84 EKDRHRKRDRHRERQRD-----REKERERQTDRERDRQRE---KERNRQKERERETEREG 135
E+DR+ +RD +R++ RD R ER+R+ +RERD++ + + R E ER+ RE
Sbjct: 604 ERDRYPERD-NRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERRE- 661
Query: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195
ER DR D + ER R+RD E+ER+R+ +RER+R ER+R++E+ERE R+ RERER+R
Sbjct: 662 ERRVDRVDDRRDERARERDRERERDRERERERER--ERDREREKERELERERARERERER 719
Query: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255
EKE E R +R +RERERE E + E++R+ +RE +R+R+ ERERE++ ERER ER
Sbjct: 720 EKERDRE-RDRDRDHDRERERERERDREKERERERE-ERERERERERERERERERERERA 777
Query: 256 TERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR 315
ERDKERER+RD + D+D+ + +R + + R+ R RD ERK +++ E +
Sbjct: 778 RERDKERERQRDWE-DKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQ 836
Query: 316 KRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERER 375
+R RE + + + EK R + + + R + E R+ +E +R+
Sbjct: 837 SPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKP 896
Query: 376 ERDRQSAR--EREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERG 433
ER S R E+E +E+ D+Q+E+ E R ++ + E S+R +
Sbjct: 897 ERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDEN 956
Query: 434 REREKQKGRERDRERQTD 451
+++ K + + ++++ D
Sbjct: 957 KKKAKIQKKPIKKKKEDD 974
Score = 207 bits (527), Expect = 2e-53
Identities = 148/466 (31%), Positives = 242/466 (51%), Gaps = 54/466 (11%)
Query: 33 SQESPRRRGLGQAHKDADG-DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKR 91
+++ R + H + D D+RER+++ R + R E E D +RE RR R
Sbjct: 613 NRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVD---RVD 669
Query: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERER 151
DR ER R+R++ERER DRER+R+RE+ER+R++E+ERE ER ER R+R +RERE+
Sbjct: 670 DRRDERARERDRERER--DRERERERERERDREREKERELER--ERARER----EREREK 721
Query: 152 QRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE 211
+RD E++R+R DRER+R+ ER+R+KERERE+ E RERER+RE+E ER RE
Sbjct: 722 ERDRERDRDRDHDRERERERERDREKERERER---EERERERERERER-------ERERE 771
Query: 212 RERERETETETERKRQTD-RERDRQRKTEREREKQAERERASERETERDKERERERDRDR 270
RERER E + ER+RQ D ++D+ R RE+ ++ +R + K ++R R+
Sbjct: 772 RERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGS 831
Query: 271 DRDRRQKERERQTDRKRQRRTERDRETERKR--------ERQRERERERERNRKRERERE 322
R+ +R R+ D + E+ R + R ++ R +E
Sbjct: 832 PSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKE 891
Query: 323 RERERERQRETERDREKERER------KRKRQTE-MDRERNRQTGREGRRQAERERERER 375
+R+ ER+ + R E+E + K++ QTE ++ R R G Q+E +R
Sbjct: 892 EDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDR 951
Query: 376 ERDRQSAREREER---ERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER 432
D + + ++ ++ ++ D ER DGQ + K+ +++K E
Sbjct: 952 AHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIE------- 1004
Query: 433 GREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQ 478
++R+K KG + + +Q+ ++R T PP T + +V+
Sbjct: 1005 -KKRKKSKGDSDISDEEAAQQSKKKRGPRT-----PPITTKEELVE 1044
Score = 206 bits (523), Expect = 6e-53
Identities = 162/533 (30%), Positives = 251/533 (47%), Gaps = 63/533 (11%)
Query: 56 RNRQKERER-RREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER- 113
R+R RE+ R + +T + DR+ ERR +D KRDR ++ + +RE E+++ + R+
Sbjct: 390 RHRSPMREKGRHDHERTSQSHDRRHERR--EDTRGKRDREKDSREEREYEQDQSSSRDHR 447
Query: 114 -DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERE----RQTDRERQ 168
DR+ R+R+ R+ RE RD + D + R+ RD ++ R+ R T
Sbjct: 448 DDREPRDGRDRRDARDTRDRRELRDSRDMR-DSREMRDYSRDTKESRDPRDSRSTRDAHD 506
Query: 169 RQTERNRQKEREREKNRQERRE--RERQREKENKTEDRHSERGRERERERETETETERKR 226
+ R R+ + +E R R RE+ ++TE R+ R R R R R
Sbjct: 507 YRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGR 566
Query: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
+ R + R + + ++ ++ + ERDR +RD R + R+ +R
Sbjct: 567 VPELPEKGSRGS-RGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFER- 624
Query: 287 RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK 346
R ERDR R+R+ QR R + R E ER+ RE ER+ + DR ER R+R
Sbjct: 625 --RHGERDRRDNRERD-QRPSSPIRHQGRNDELERDERRE-ERRVDRVDDRRDERARERD 680
Query: 347 RQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK 406
R+ E DRER ERERERER+R+R E+ER+ +R+R +ERER+ EK
Sbjct: 681 RERERDRER------------ERERERERDRER-------EKERELERERAREREREREK 721
Query: 407 DRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVN 466
+RD +R+ ++ +RE++RE ER RE+ RERE+++ RER+RER+ +R+ R+R+R
Sbjct: 722 ERDRERDRDRDHDRERERERERDREKEREREREE-RERERERERERERERERERERARER 780
Query: 467 PPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPR 526
R + D R R + + ED G + S+ R PR
Sbjct: 781 DKERERQRDWEDKDKGRDDRREKREEIREDRNPRD-----GHDERKSKKRYRNEGSPSPR 835
Query: 527 LGEKRGQGGEGRRPSGGFGTENPLSQAPSVFPGPRYTPGDGKRNVHTVLSVFV 579
KR + +P S A Y GD K H +LS V
Sbjct: 836 QSPKRRR------------EHSPDSDA--------YNSGDDKNEKHRLLSQVV 868
Score = 191 bits (486), Expect = 1e-48
Identities = 116/405 (28%), Positives = 207/405 (51%), Gaps = 31/405 (7%)
Query: 23 PLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERR 82
P+ R + RR D D+R R R +ERER RE+ ERE +R+R+R
Sbjct: 644 PIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRER---ERERERERDRE 700
Query: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142
REK+R +R+R RER+R+REKER+R+ DR+RD RE+ER R+++RE+E ERE E
Sbjct: 701 REKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE------ 754
Query: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKE-REREKNRQERRERERQREKENKT 201
+ +RERER+R+ E+ERER+ +R R+R ER RQ++ +++K R +RRE+ + ++
Sbjct: 755 -ERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNP 813
Query: 202 EDRHSERGRER--------------ERERETETETERKRQTDRERDRQRKTEREREKQAE 247
D H ER ++ +R RE +++ D + ++ R + Q
Sbjct: 814 RDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQES 873
Query: 248 RERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER 307
R + TE + R +E DR +R + E Q +++ ++ RE E R R
Sbjct: 874 RSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMR 933
Query: 308 ERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQA 367
++ + + E +R + ++ + ++K ++K++ ++R T +G+ +
Sbjct: 934 AQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFS 993
Query: 368 ERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
++ ++++ + E++ ++ D D E Q K + G R
Sbjct: 994 PKKGQKKK------SIEKKRKKSKGDSDISDEEAAQQSKKKRGPR 1032
Score = 182 bits (461), Expect = 1e-45
Identities = 119/419 (28%), Positives = 206/419 (49%), Gaps = 90/419 (21%)
Query: 56 RNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDR 115
RN + ER+ RRE+R+ +R DR+ ER RE+DR R+RDR RER+R+RE++RER E++R
Sbjct: 650 RNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRER----EKER 705
Query: 116 QREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNR 175
+ E+ER R++ERERE ER+ ER RDR D +RERER+RD EKERER+ + ER+R+ ER R
Sbjct: 706 ELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE-ERERERERER 764
Query: 176 QKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQ 235
++ERERE+ R+ RER+++RE++ ED+ ++GR+ RE+ E +R + + +
Sbjct: 765 ERERERERERERARERDKERERQRDWEDK--DKGRDDRREKREEIREDRNPRDGHDERKS 822
Query: 236 RKTERE-------REKQAERERASERETERDKERERERDR-------------------D 269
+K R + + RE + + + + + E+ R
Sbjct: 823 KKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLT 882
Query: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKR---ERQRER------------------- 307
DR R KE +R+ +RK R ++E + K ++QRE+
Sbjct: 883 EDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQ 942
Query: 308 -------ERERERNRKRERERERE----------------------------RERERQRE 332
+R + N+K+ + +++ ++ ++++
Sbjct: 943 SEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKS 1002
Query: 333 TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391
E+ R+K + E ++ ++ G +E E + E +++ D
Sbjct: 1003 IEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKED 1061
Score = 107 bits (266), Expect = 4e-23
Identities = 86/336 (25%), Positives = 151/336 (44%), Gaps = 31/336 (9%)
Query: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQER-----RERERQREKE 198
D R+ R R + E T + Q + ++++ NR R R R +
Sbjct: 1155 DSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSA 1214
Query: 199 NKTEDRHSER-------GRERERERETETETERKRQTDRERDRQRKTEREREKQAERERA 251
+++ D S R R+RE+ + E ERK + D+ + + ++Q R +
Sbjct: 1215 HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHS 1274
Query: 252 SERET-ERDKE----------RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERK 300
S R + E D++ R+R ++RDR R++ERER+ R+R+ + D++ R
Sbjct: 1275 SRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRN 1334
Query: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
R+R R RERERER R + R+ +RERER ERDR+++R+R + +R
Sbjct: 1335 RDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKR----- 1389
Query: 361 REGRRQAERERERERERDRQSAREREERERDRDRDR---QKERERQTEKDRDGQRETEKQ 417
E + + E ER+ E A ++E ++D + + + +TE G E++
Sbjct: 1390 CEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLD 1449
Query: 418 REREKDRESERGRERGREREKQKGRERDRERQTDRQ 453
+ G E + E + D E++ D+Q
Sbjct: 1450 DAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQ 1485
Score = 105 bits (262), Expect = 1e-22
Identities = 113/516 (21%), Positives = 202/516 (39%), Gaps = 98/516 (18%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERN---------RQKERERRREKRQ---TERET 75
RR P R + +D D + ++RN ++ R R REK T+ T
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERT 134
Query: 76 DRKRERRREKDRHRKRDRHRERQRDREKERERQTDR---ERDRQREKERNRQKERE---- 128
E E + +R + + D E + R +R+ + ++ N +K E
Sbjct: 135 PESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIK 194
Query: 129 ------------------RETEREGERGRDRQTDGQRERERQRDA------EKERERQTD 164
R++ + +R ++ +++R+ A +++R +T+
Sbjct: 195 KEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTN 254
Query: 165 RER--------------------QRQTERNRQKEREREKNRQER---RERERQREKENK- 200
+ + ++ E+ + K+R EK R + R+ ERQREK +K
Sbjct: 255 QSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKP 314
Query: 201 ------------TEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAER 248
RH + + + + R+++T ++ T R +
Sbjct: 315 RSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPY 374
Query: 249 ERASERETERDKERERERDRDRDRDRRQKERERQT-DRKRQRRTE----RDRETERKRER 303
S +R + R R R++ R ER Q+ DR+ +RR + RDRE + + ER
Sbjct: 375 PSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREER 434
Query: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363
+ E+++ R+ + +RE R+R R+T RDR + R+ + R + R+ +R T
Sbjct: 435 EYEQDQSSSRDHRDDREPRDGRDRRDARDT-RDRRELRDSRDMRDSREMRDYSRDT---- 489
Query: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERER-------QTEKDRDGQRETEK 416
+++ R+ RD R+RE R+ R D E R + E R R +
Sbjct: 490 -KESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESR 548
Query: 417 QREREKDRESERGRERGRERE-KQKGRERDRERQTD 451
R + R GR RGR E +KG R Q D
Sbjct: 549 NESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQID 584
Score = 100 bits (250), Expect = 3e-21
Identities = 85/289 (29%), Positives = 128/289 (44%), Gaps = 29/289 (10%)
Query: 163 TDRERQRQTERNRQKEREREKNRQERRER-----ERQREKENKTEDRHSERGRERERERE 217
T T N R+ + R E+ E E + ++ + R S G R
Sbjct: 1142 TPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSH 1201
Query: 218 TE------TETERKRQTDRERDRQR---KTEREREKQAERERASERETERDKERERERDR 268
T + R D + R+R R+REK E ER++ D+ + E R
Sbjct: 1202 TSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSR 1261
Query: 269 DRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR-KRERERERERER 327
DR+ + ++ R+ E DR+ + R+R +ER+R + +RERERER
Sbjct: 1262 STSSDRQ----DSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRD 1317
Query: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
RQRE +RD +K+ R R R +RER R+ R+ RR +RERER + E
Sbjct: 1318 TRQREWDRDADKDWPRNRDRDRLRERERERE--RDKRRDLDRERER-------LISDSVE 1368
Query: 388 RERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRER 436
R+RDRDRDR E Q E + + + E + ER+ + S +ER
Sbjct: 1369 RDRDRDRDRTFE-SSQIESVKRCEAKLEGEHERDLESTSRDSLALDKER 1416
Score = 100 bits (249), Expect = 4e-21
Identities = 123/578 (21%), Positives = 214/578 (37%), Gaps = 114/578 (19%)
Query: 68 KRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNR---Q 124
+R ER T RER + K ++D E Q+ +E +E R R +E+
Sbjct: 75 RRSPERPTGDLRERMKNK----RQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKIT 130
Query: 125 KERERETEREG---ERGRDRQTDGQRERERQRDAEKERERQ-TDRERQRQTERNRQKERE 180
KER E+E E E RD +G + + E +RQ RE + + N +K E
Sbjct: 131 KERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREE 190
Query: 181 REKNRQERRERERQR-------EKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
++ E R + K +K+ R S +++ +T D++R+
Sbjct: 191 IIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRN 250
Query: 234 RQRKTERER------------------EKQAERERASERETERDKE-RERERDRDRDRDR 274
+ +++ +K E+ + +R E+ ++ ++R RD +R R++
Sbjct: 251 SKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREK 310
Query: 275 RQKER---------------------------ERQTDRKRQRRT---------------- 291
R K R +R + R++RT
Sbjct: 311 RDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRS 370
Query: 292 ----------ERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
R+ R R RE+ R + + + +R ER +RDREK+
Sbjct: 371 ASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDS 430
Query: 342 ERKRKRQTEMDRERNRQTGRE-----GRRQAERERERERERDRQSARE-REERERDRD-- 393
+R+ + + R+ + RE RR A R+R RD + R+ RE R+ RD
Sbjct: 431 REEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTK 490
Query: 394 -----RDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE-----KQKGRE 443
RD + R+ +DR+G R+T ++ + + GR RE + + R
Sbjct: 491 ESRDPRDSRSTRDAHDYRDREG-RDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRN 549
Query: 444 RDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTR 503
R + + GR R R R +R + S + W++ P+ R
Sbjct: 550 ESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPE--RDR 607
Query: 504 FPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRPS 541
+P +R RR E ++R +RPS
Sbjct: 608 YPERDNRDQARDSSFERRHGE---RDRRDNRERDQRPS 642
Score = 95.1 bits (235), Expect = 2e-19
Identities = 70/336 (20%), Positives = 153/336 (45%), Gaps = 21/336 (6%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK-RQTERETDRKRERRR 83
D R R +E R + + ++ + +RER R++ERER RE+ R+ RE D++RER+R
Sbjct: 732 DHDRERERERERDREK---EREREREERERERERERERERERERERERARERDKERERQR 788
Query: 84 E-KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142
+ +D+ + RD RE++ + ++R + + + +++ RN R++ +
Sbjct: 789 DWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKR-------- 840
Query: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202
+RE DA + + ++ R Q+ R + + R +E++ K E
Sbjct: 841 ---RREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPE 897
Query: 203 DRHSERGRERERERETETETERKRQTDR--ERDRQRKTEREREKQAERERASERETERDK 260
+ S R E + +E + +++R+ E R R + Q+E S+R + +K
Sbjct: 898 RKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENK 957
Query: 261 ERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
++ + + + +++KE + +R T D + ++ Q+++ E++R + +
Sbjct: 958 KKAKIQKKP---IKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDS 1014
Query: 321 RERERERERQRETERDREKERERKRKRQTEMDRERN 356
+ E +Q + +R ++ EM +N
Sbjct: 1015 DISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKN 1050
Score = 93.2 bits (230), Expect = 6e-19
Identities = 74/255 (29%), Positives = 122/255 (47%), Gaps = 31/255 (12%)
Query: 23 PLDFSRRRPGSQESPRRRGLGQAHKDAD--------GDDRERNRQKERERRREKRQTERE 74
P + S R G +S R+R L +D + G+ + R Q +R ++R+
Sbjct: 1209 PSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQ 1268
Query: 75 TDRKRERRR---EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKER--NRQKERER 129
R RR E DR RDR +ER+R E DR+RE+ER RQ+E +R
Sbjct: 1269 DSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY---EHDRERERERRDTRQREWDR 1325
Query: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQ-ER 188
+ +++ R RDR R RER+R+ E+++ R DRER+R + +++R+R+++R E
Sbjct: 1326 DADKDWPRNRDR----DRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFES 1381
Query: 189 RERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER-DRQRKTEREREKQAE 247
+ E + E K E H ER+ E+ + D+ER D+ + + E+ +
Sbjct: 1382 SQIESVKRCEAKLEGEH---------ERDLESTSRDSLALDKERMDKDLGSVQGFEETNK 1432
Query: 248 RERASERETERDKER 262
ER E D+ +
Sbjct: 1433 SERTESLEAGDDESK 1447
Score = 92.8 bits (229), Expect = 8e-19
Identities = 81/303 (26%), Positives = 132/303 (43%), Gaps = 29/303 (9%)
Query: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERER 151
D HR+ R R ++ E D Q K +++R + R T G+
Sbjct: 1155 DSHRKCHRTRVEKVETPHVTIEDAQHRKPM----DQKRSSSLGSNRSNRSHTSGRLRSPS 1210
Query: 152 QRDAEKERERQTDRERQRQT-ERNRQK--------EREREKNRQERRERERQREKENKTE 202
A + + Q+ R+R + R+R+K ER+ ++ +R E R + +
Sbjct: 1211 NDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDS 1270
Query: 203 DRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKER 262
HS R E +R+ + + DR ++R R E +R ERE ++R
Sbjct: 1271 RSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY---------EHDRERERERRDTRQR 1321
Query: 263 ERERDRDRDRDR---RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRER 319
E +RD D+D R R + RER+ +R+R +R + DRE ER ER+R+R+R+R E
Sbjct: 1322 EWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFES 1381
Query: 320 ---ERERERERERQRETERDREK-ERERKRKRQTEMDRERNRQTGREGRRQAERERERER 375
E + E + + E ERD E R+ + MD++ G E ++ER E
Sbjct: 1382 SQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEA 1441
Query: 376 ERD 378
D
Sbjct: 1442 GDD 1444
Score = 91.3 bits (225), Expect = 2e-18
Identities = 61/243 (25%), Positives = 111/243 (45%), Gaps = 17/243 (6%)
Query: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKE- 278
T T T D RK R R ++ E + + + K +++R +R +
Sbjct: 1142 TPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSH 1201
Query: 279 ---RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER 335
R R R+ D+ ++ R+RE+ ++ + ER+ ++ ++ E R
Sbjct: 1202 TSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSR 1261
Query: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
+R+ R + R++ E RQ RDR R+R E +R+R+R+
Sbjct: 1262 STSSDRQDSRSHSS-------RRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERE 1314
Query: 396 RQKERERQTEKD--RDGQRETEKQREREKDRESERGRERGREREKQK----GRERDRERQ 449
R+ R+R+ ++D +D R ++ R RE++RE ER + R +RE+++ ERDR+R
Sbjct: 1315 RRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRD 1374
Query: 450 TDR 452
DR
Sbjct: 1375 RDR 1377
Score = 89.7 bits (221), Expect = 7e-18
Identities = 79/276 (28%), Positives = 119/276 (43%), Gaps = 33/276 (11%)
Query: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
S R S S R R GDD+ ++ R++ +T + + ER+ D
Sbjct: 1194 SNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKT-KSLEITGERKSRID 1252
Query: 87 RHRKRDRHRERQRDREKERE---RQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143
+ ++ + R DR+ R R++ E DRQ R+R ER DR
Sbjct: 1253 QLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQER------DRY- 1305
Query: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203
+ +RER+R+ R+R+ DR+ + RNR ++R RE RERER+R+K
Sbjct: 1306 --EHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRE------RERERERDK------ 1351
Query: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAER-ERASERETERDKER 262
R +RERER ER DR+RDR R E + + +R E E E ERD E
Sbjct: 1352 ---RRDLDRERERLISDSVER----DRDRDRDRTFESSQIESVKRCEAKLEGEHERDLES 1404
Query: 263 ERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
D++R K+ + ++ER E
Sbjct: 1405 TSRDSLALDKERMDKDLGSVQGFEETNKSERTESLE 1440
Score = 88.2 bits (217), Expect = 2e-17
Identities = 74/230 (32%), Positives = 112/230 (48%), Gaps = 25/230 (10%)
Query: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHR 89
R S ES R Q H + D R+R +ER+R R+ ERE R+ R+RE DR
Sbjct: 1276 RRSSPESDR-----QVHSRSGSFD-SRDRLQERDRYEHDRERERE--RRDTRQREWDRDA 1327
Query: 90 KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG-QRE 148
+D R R RDR +ERER+ RERD++R+ +R R++ ER+ +R RDR + Q E
Sbjct: 1328 DKDWPRNRDRDRLRERERE--RERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIE 1385
Query: 149 RERQRDAEKERERQTDRERQRQTERNRQKERE----------REKNRQERRERERQREKE 198
++ +A+ E E + D E + KER E N+ ER E + E
Sbjct: 1386 SVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDE 1445
Query: 199 NKTEDRHS-ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAE 247
+K +D HS G E ++ E + D E+ R+ +++ EK +
Sbjct: 1446 SKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEK---REDQQDEEKMPD 1492
Score = 84.7 bits (208), Expect = 2e-16
Identities = 70/269 (26%), Positives = 126/269 (46%), Gaps = 27/269 (10%)
Query: 187 ERRERERQREKENKTEDRH-----SERGRERERERETETETERKRQTDRERDRQRKTERE 241
E R+ R + K E H ++ + +++R + + R ++ R R +
Sbjct: 1154 EDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTS-GRLRSPSND 1212
Query: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR-KRQRRTERDRETERK 300
++ +++ + R+RE+ + + +K R Q R + R T DR+ R
Sbjct: 1213 SAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRS 1272
Query: 301 RERQRER-ERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQT 359
+R E +R+ + + R+R +ER R E DRE+ERER+ RQ E DR+
Sbjct: 1273 HSSRRSSPESDRQVHSRSGSFDSRDRLQERDRY-EHDRERERERRDTRQREWDRD----- 1326
Query: 360 GREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRE 419
A+++ R R+RDR ERER+R+RD++++ +R+ E+ E ++ R+
Sbjct: 1327 -------ADKDWPRNRDRDRL-----RERERERERDKRRDLDRERERLISDSVERDRDRD 1374
Query: 420 REKDRESERGRERGREREKQKG-RERDRE 447
R++ ES + R K +G ERD E
Sbjct: 1375 RDRTFESSQIESVKRCEAKLEGEHERDLE 1403
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 219 bits (559), Expect = 4e-57
Identities = 140/526 (26%), Positives = 271/526 (51%), Gaps = 32/526 (6%)
Query: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRE----RRREKDRHRKRDRHRERQR 99
Q ++ ++ + + + +E RRE+++ E++ R R RR++++ R++ R Q+
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 100 DREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKER 159
+R +++E + +++ R++E+ R +Q RE+E ER ++ R Q + +RE++ +R+ + R
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Query: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKE---NKTEDRHSERGRERERER 216
E+Q RE+Q + E+ ++E++ + +Q RRE++ +RE++ + E+RH ++ + RE+
Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276
+ E E +R + + + E+ER KQ + E ER + E E R++ ++RR+
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ-QERRE 504
Query: 277 KERERQTDRKRQRRTERDRETERKRER-------QRERERERERNRKRERERERERERER 329
++ R+ + +R++R +R E ER ++R +RE+E RE+ KRE E+ E+ER
Sbjct: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
Query: 330 QR-----ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARE 384
QR E RD+ +RE +R++Q + R R R + ER + ER R E
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
Query: 385 REERERD---RDRDRQKERERQTEKDRDGQRETEKQREREKDRESER-GRERGREREKQK 440
EE R + ++++ R++Q +++ +RE +RE E++R +R RE ER +Q+
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Query: 441 GRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAA 500
E ++E+ +R R K + AR V S P + R + E +
Sbjct: 685 LAEEEQEQARERIKSRIPKWQ--WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
Query: 501 STRFPWGRPAKASRGRVAGRRR------WEPRLGEKRGQGGEGRRP 540
+ W +A R + +R W+ +RG+ RP
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Score = 219 bits (558), Expect = 6e-57
Identities = 158/539 (29%), Positives = 287/539 (53%), Gaps = 43/539 (7%)
Query: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88
RR G +E ++R Q + +++E +++ R+ E++ E E R+RE + E+++
Sbjct: 219 RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 89 RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148
RK +R +E +R+R++E E+Q R R Q+ + + ++ RE++ ER ++ R Q + +RE
Sbjct: 279 RKLER-QELRRERQEE-EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
Query: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR-HSE 207
++ +R+ E+ RE+Q RE Q + R +Q RE+E +ERRE++ +RE++ + E + E
Sbjct: 337 QQLRREQEERREQQLRRE-QEEERREQQLRREQE---EERREQQLRREQQLRREQQLRRE 392
Query: 208 RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
+ RE++ E + R++Q RE+ +R+ + RE++ ER + R++ +RE++
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
Query: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKR-------ERQRERERERERNRKRERE 320
RD +R++E ER +R+++ +RD+E ER+ E +RE++ RE+ +RE+E
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512
Query: 321 RERERERERQRETE-------------RDREKERERKRKRQTEMDRERNRQTGREGRRQA 367
RE+ +RQ E E R++E+ RE+ KR+ E E+ R+ R R Q
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE 572
Query: 368 ERERE---RERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR------ETEKQR 418
ER + RE ER RQ +RE+ ER R +++E ER +++R QR E E+++
Sbjct: 573 ERRDQLLKREEER-RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQ 631
Query: 419 EREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQR-KRSTLYVNPPPRTARSGVV 477
+ K E E R++ RE+Q+ RE+ +R+ + + QR KR A
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Query: 478 QSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGE 536
Q+ +R +W+ E A + RP K G+RR + + ++R + E
Sbjct: 692 QARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE-----GQRRRQEQEEKRRRRESE 745
Score = 219 bits (557), Expect = 7e-57
Identities = 133/438 (30%), Positives = 256/438 (58%), Gaps = 19/438 (4%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD-RKRER--RREKDRHRK 90
+E RRR L + + RE +Q+ RER+ Q E E + RKRE R+E+++ ++
Sbjct: 207 EEQLRRRELLELRRKG----REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Query: 91 RDRHRERQRDREKERERQTDRE---RDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
+ R+R+ E+E+ R+ +R+ R+RQ E+++ ++ RE++ R+ E R Q + +R
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207
E++ +R+ ++ER Q R R+++ R +Q RE+E+ R+E++ R R++E+E + + E
Sbjct: 323 EQQERREQQEERREQQLR-REQEERREQQLRREQEEERREQQLR-REQEEERREQQLRRE 380
Query: 208 RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
+ RE++ E + R++Q RE+ +R+ + RE+Q RE+ RE E ++ ++
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER-ERNRKRERERERERE 326
R++ ++++ ER+ KR+ TER + RK++ +R++E ER ER K E E RE++
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500
Query: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
R+++ R++E+ RE++ KRQ E +R + R R + + RE+E R++ RE E
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRL-----RSEQQLRREQEERREQLLKREEE 555
Query: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER-GREREKQKGRERD 445
+R R+++ +RE++ +D+ +RE E++++R K + ER +R RE ++ +E
Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER 615
Query: 446 RERQTDRQAGRQRKRSTL 463
RE++ R+ + +R L
Sbjct: 616 REQRLKREEPEEERRQQL 633
Score = 216 bits (550), Expect = 5e-56
Identities = 154/503 (30%), Positives = 262/503 (52%), Gaps = 44/503 (8%)
Query: 58 RQKERERRREKRQTERETDRKRER---RREKDRHRKRDRHRERQRDREKERERQTDRERD 114
R+K+ E RRE+++ RE +RE+ RRE+ R+++ RE+Q RE+E ER+ + R
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR 366
Query: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE----RQRQ 170
Q E+ R +Q RE++ RE + R++Q +RE++ +R+ + RE+Q RE R++Q
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQQLRREQQ 424
Query: 171 TERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDR 230
R +++ER +K+ QERRE+ +RE+E + + +RE E E + RK+Q R
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERRD------WLKREEETERHEQERRKQQLKR 478
Query: 231 ERDRQRKTEREREKQAERERASERETERDKERERERDRDRD-RDRRQKERERQTDRKR-- 287
+++ +R RER + E E E++ R+++ RE++ R+ R +RQ+E ER R R
Sbjct: 479 DQEEER---RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 288 ---QRRTERDRETERKRERQRERERERERNR-KRERERERER--ERERQRETERDREKER 341
+R E RE KRE ++ E+ER R KRE+E R++ +RE +R +R + ++
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE 401
ER +R + ER Q R +R E E ER + + E+EER + + R Q+ER
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 402 RQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRER----QTDRQAGRQ 457
Q K + + E++ +RE E ER + E E+++ RER + R Q ++
Sbjct: 656 EQRLKREEEEERLEQRLKRE--HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEAD 713
Query: 458 RKRSTLYVNPPPRTARSGVVQSDPNRPTR--GIRW-------KSSPEDPKAASTRFPWGR 508
++S +Y P + + + + R R ++W + E+ + + W
Sbjct: 714 ARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQA 773
Query: 509 PAKASRGRVAGRRRWEPRLGEKR 531
K+ RGR R P L E+R
Sbjct: 774 EEKSERGR--QRLSARPPLREQR 794
Score = 212 bits (539), Expect = 9e-55
Identities = 133/425 (31%), Positives = 248/425 (58%), Gaps = 24/425 (5%)
Query: 56 RNRQKERE---RRREKRQT-ERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDR 111
R+RQ E E RRR+KRQ ERE E+ +++R +RDR R RD E R+RQ +
Sbjct: 125 RDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR---RDEELWRQRQEWQ 181
Query: 112 ERDRQREKERNRQKERERETEREGERGRDRQTD-------GQRERERQRDAEKERERQTD 164
ER+ +R +E Q + ETE + + R+ + G+ E+++QR ++R Q +
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE 241
Query: 165 RERQ-RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETE 223
E++ R+ E +KE E+ + + +R+RE Q E+E + E RER+ E + +
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301
Query: 224 RKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD-RRQKERERQ 282
R++Q R+++ +R+ E++ E++ ++ER ++E R+++ RE++ R++ RR++E ER+
Sbjct: 302 REQQLRRKQEEERR-EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
Query: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342
+ R+ + E RE + +RE+Q RE++ R ++ RE++ RE++ +RE + RE++
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERD---RQSAREREERERDRD---RDR 396
R+++ + E + ER+ Q + RR+ +RE+E RD R+ ER E+ER + RD+
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 397 QKE-RERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAG 455
++E RER + + + +RE +++RE++ RE E RE+ +R++++ R + R R +
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Query: 456 RQRKR 460
Q +R
Sbjct: 541 EQEER 545
Score = 211 bits (536), Expect = 2e-54
Identities = 127/459 (27%), Positives = 257/459 (55%), Gaps = 35/459 (7%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRD- 92
QE +RR + + + +R RQK +E+ RE + E +++ K+ER ++DR R+ +
Sbjct: 115 QEEDQRR-FEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE-KQERLEQRDRQRRDEE 172
Query: 93 --RHRERQRDREKER--------------ERQTDRERDRQREKERNRQKERERETEREGE 136
R R+ ++RE+ R E D E+ R+RE R+K RE + ++ E
Sbjct: 173 LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRE 232
Query: 137 RGRDRQTDGQRERE---RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
R +DR + E+E R+ KE E+ + E QRQ E ++E+ R+ RQE R +
Sbjct: 233 R-QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ 291
Query: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
+ E++ + R + R++E ER + E R++Q RE+ +R+ ++ R +Q ER
Sbjct: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351
Query: 254 RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER 313
R + ++ RE++ R+++ +RR+++ R+ +R+++ R+++ R+++ +RE++ RE+
Sbjct: 352 RREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 411
Query: 314 NRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERER 373
+RE++ RE++ R++E ER +K + +R+++ + ++E R +R+ E ER
Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW---LKREEETERHE 468
Query: 374 ERERDRQSAREREERERDR--------DRDRQKERERQTEKDRDGQRETEKQREREKDRE 425
+ R +Q R++EE R+R R++Q+ RE+Q ++++ +RE +R+ E++R
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
Query: 426 SERGR-ERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
+R R E+ RE+++ RE+ +R+ +++ ++R+ L
Sbjct: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
Score = 209 bits (532), Expect = 6e-54
Identities = 144/495 (29%), Positives = 266/495 (53%), Gaps = 42/495 (8%)
Query: 32 GSQESPRRRGLGQAHKDADGDDRERNRQK--ERERRREKRQ---------TERETDRKRE 80
G ++S ++ L Q + ++ R RQ+ ERE RR + + TE D ++
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
Query: 81 RRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD 140
RRRE R++ R ++Q+ RE++ + E R++E +KE E+ E E +R R+
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRE--RERQREKE 198
Q + ++ R+ +R E RERQ + ++Q++ R +Q R++E+ R+E++E RE+Q +E
Sbjct: 271 LQEEEEQLRKLERQ-ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329
Query: 199 NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERE-REKQAERERASERETE 257
+ E R + RE+E RE + E++ + RE+ +R+ E E RE+Q RE+ RE +
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEER-REQQLRREQEEERREQQLRREQQLRREQQ 388
Query: 258 RDKERERERDRDRDRDR-----RQKERERQTDRKRQRRTERDRETERKRERQRERE---- 308
+E++ R++ R++ +Q RE+Q R++Q R E++ E ++ Q RE
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448
Query: 309 RERERNR---KRERERERERERERQRETERDREKER-------ERKRKRQTEMDRERNRQ 358
RE+E R KRE E ER + R+++ +RD+E+ER E + +R+ + RE+ +
Sbjct: 449 REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508
Query: 359 TGREGRRQAERERERERERDRQSARE----REERERDRDRDRQKERERQTEKDRDGQ--- 411
+E RR+ +R+ E ER +Q R R E+E R++ ++E E++ E++R Q
Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568
Query: 412 RETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRT 471
RE E++R++ RE ER ++R + ++++ +R + + +R +R+ L P
Sbjct: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
Query: 472 ARSGVVQSDPNRPTR 486
R +++S+ R
Sbjct: 629 RRQQLLKSEEQEERR 643
Score = 208 bits (529), Expect = 1e-53
Identities = 133/449 (29%), Positives = 259/449 (57%), Gaps = 32/449 (7%)
Query: 42 LGQA-----HKDADGDDRER----NRQKERERRREKRQTERETD---RKRERRREKDRHR 89
LGQA K A D +E RQ+E +RR E R + E + R+R++R+E++R
Sbjct: 89 LGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL 148
Query: 90 KRDRHRERQRDREKERERQT-DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148
+ +++R ++R+RQ D E RQR++ + R++ R E + + +G + + E
Sbjct: 149 AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEE 208
Query: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQ-REKENKTEDRHSE 207
+ R+R+ + R + RE ++Q R RQ +E+ +E R+RE R++E K ++ +
Sbjct: 209 QLRRRELLELRRK--GREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQ 266
Query: 208 RGRERERERETETETERKR-QTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
R RE + E E + ER+ + +R+ + Q++ RE+Q R++ ER ++++ RE++
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR---KRERERER 323
R++ +RR+++ R+ + +R+++ R++E ER RE+Q RE+E ER +RE++ R
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEER-REQQLRREQEEERREQQLRREQQLRR 385
Query: 324 ERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER-ERERERDRQSA 382
E++ R+++ R+++ RE++ +R+ ++ RE+ + ++ RR+ E ER E++ E++R+
Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 383 REREERERDRD---RDRQKERERQTEKDRDGQRETEKQR-------EREKDRESERGRER 432
R + E+E RD R+ + ER Q + + +R+ E++R E E+ RE + RE+
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ 505
Query: 433 GREREKQKGRERDRERQTDRQAGRQRKRS 461
RE+++ RE+ +RQ + + +QR RS
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLRS 534
Score = 206 bits (523), Expect = 6e-53
Identities = 141/498 (28%), Positives = 269/498 (54%), Gaps = 58/498 (11%)
Query: 30 RPGSQESPRRRG--LGQAHKDADGDDRERNRQKERERR-REKRQTERETD------RKRE 80
+P QE R+ L + ++ ++RE+ R++E+ER+ RE+ Q ++E + R++
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951
Query: 81 RRREKDRHRKRDRH----------RERQRDREKERERQTDRERDRQREKERNRQKERERE 130
RR+E++R ++D+ E ++ R +ERE++ E + Q+E+E+ ++ERE+
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011
Query: 131 TEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERER----EKNRQ 186
+E ER ++ + Q+E E+ E+E+ R +RERQ + E Q+E E+ E+ +
Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR 1071
Query: 187 ERRERERQREKENKTEDRHS-------ERGRERERERETETETERKRQTDR----ERDRQ 235
R+E ERQ KE + + E+ R +ERER+ E E +++ ++ ER+++
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR 295
R+ E ER+ + E E E E +E E+ R ++ +R R++E +Q + + R + R
Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191
Query: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDRE--------KERERKRKR 347
ER+R+ + E E +R++ ++R R+ ++ + + Q E E++ K RE ++ R
Sbjct: 1192 RQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Query: 348 QTEMDRERNRQT--------GREGRRQAERERERERERDR----QSAREREERERDRDRD 395
Q E + R+RQ+ G + R E+ER R ++RDR + EREE++ + RD
Sbjct: 1252 QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD 1311
Query: 396 RQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAG 455
R+ + E+Q ++ +RE EK+R +E DR+ + +ERE+Q R ++R+R+ +
Sbjct: 1312 RKSQEEKQLLRE---ERE-EKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEEL 1367
Query: 456 RQRKRSTLYVNPPPRTAR 473
R +++ ++ R R
Sbjct: 1368 RHQEQGRKFLEEEQRLRR 1385
Score = 204 bits (519), Expect = 2e-52
Identities = 158/541 (29%), Positives = 258/541 (47%), Gaps = 109/541 (20%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKR-----QTERETDRKRER--RREKD 86
QE RR Q ++ + + RE+ ++E++ RRE++ Q RE +RE+ RRE+
Sbjct: 355 QEEERREQ--QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Query: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKE-------RERETEREGERGR 139
R++ RE+Q RE+E ER + +RE+ R++E RE ETER + R
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
Query: 140 DRQTDGQRERERQR---DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196
+Q +E ER+ E+E R+ R++Q R +++ RE+ RQE ER +QR
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532
Query: 197 KENKTEDRHSERGRER--ERERETETETER-----KRQTDRERDRQRKTEREREKQ---- 245
+ + R E RE+ +RE E E ER KR+ + RD+ K E ER +Q
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
Query: 246 --------------AERERASERETERDKERERERDR-------DRDRDRRQKERERQTD 284
ER ER +R K E E +R + +RRQ++ R+
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 285 RKRQRRTERDRETERKRER-QRERERERERNRKRERERERERE----------------- 326
+R++R +R+ E ER +R +RE E ER E E+E+ RE
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712
Query: 327 ---------RERQRETERDREKERERKRKRQTEM-----DRERNRQTGREGRR----QAE 368
R R++E +R R+++ E++R+R++E+ +R +Q E RR Q +
Sbjct: 713 DARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQ 772
Query: 369 RERERERERDRQSARE--REERERD-RDRDRQKERERQTEKDRDGQRETEKQREREKD-- 423
E + ER R R SAR RE+RER R +RQ+ +R ++ + ++ ++REREK+
Sbjct: 773 AEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ 832
Query: 424 -----------------RESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVN 466
+E E G + +ER + + + RD++ + + R+R+R TLY
Sbjct: 833 FLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892
Query: 467 P 467
P
Sbjct: 893 P 893
Score = 202 bits (513), Expect = 9e-52
Identities = 135/477 (28%), Positives = 266/477 (55%), Gaps = 45/477 (9%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREKD 86
RR+ ++ + + L Q + G++ E+ R++ERE++ RE+ + ++E ++ REK
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011
Query: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGER--GRDRQTD 144
R ++ +R ++ + ++E E+ ER+++R +ER RQ E E ++E E+ G +R+T
Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR 1071
Query: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKERERE-KNRQERRERERQREKENKTED 203
++E ERQ E+E +++ ++ + + E+ R++ERER+ + +E ++ E Q +E + +
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTERE---------------------R 242
R E R+ E E + E E+ + + E+ R+++ ER+ R
Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191
Query: 243 EKQAERERASERETERDKERERERDRDRDRDRR-QKERERQT---DRK-----RQRRTER 293
++ ER+ E E +R K ++R RD D+ D + Q E E++ D K R+ R
Sbjct: 1192 RQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Query: 294 DRETERKRERQRERE------RERERNRKRERERERERERERQRETERDREKERERKRK- 346
E + R+RQ +++ ++ER+R++ER R ++R+R E + +RE+++E KR+
Sbjct: 1252 QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD 1311
Query: 347 RQTEMDRERNRQTGREGRRQAERERE-RERERDRQSAREREERERDRDRDRQKERERQTE 405
R+++ +++ R+ E RR+ E +R+ RE E+ Q E+ R ++RDR ++E R E
Sbjct: 1312 RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQE 1371
Query: 406 KDRDGQRETEKQREREKDRE--SERGRERGREREKQKGRERDRE-RQTDRQAGRQRK 459
+ R E ++ R +E++R+ E + R +ERE+Q ++RDR+ R+ ++Q RQ +
Sbjct: 1372 QGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER 1428
Score = 201 bits (511), Expect = 2e-51
Identities = 143/483 (29%), Positives = 256/483 (53%), Gaps = 53/483 (10%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRRE---KRQTERETDRKRER--- 81
RRR +E RRR ++ ++R +Q+E E+RR+ + Q E +++R R+R
Sbjct: 730 RRRQEQEEKRRRR---ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786
Query: 82 ----RREKDRH-RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
R +++R R +R + QR +E E++ R + R+REKE +E E+ RE
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA 846
Query: 137 RGRDRQTDG-QRERERQRDAEKERER------QTDRERQRQT-------------ERNRQ 176
+ + DG Q ++ER+R E+ R++ + +R+R+R T E+
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
Query: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRER--ERERETETETERKRQTDRERDR 234
+E E E R+ER +R RQ ++ E+ ++ E+ ERE ER+RQ +++
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 235 QRKTEREREKQAERERASERETERDKERERERD-----RDRDRDRRQKERERQTDRKRQR 289
Q+K E+ ++ E+ R ERE + +E E +++ R+ RR++E ERQ +K +
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 290 RTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQT 349
+ E ++ +RE++R +ERER+ + E ++E E+ +RET R +E ER+ +++ +
Sbjct: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 350 EMDRERNRQTGREGRRQAERERERERERDRQSARE---REERERDR----DRDRQKERER 402
+ + E+ + E RR+ ERER+ E + Q E REERE+ R +R ++E E
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEV 1146
Query: 403 QTEKDRDGQRETEKQREREKDRESERGRERGRE-----REKQKGRERDRERQTDRQAGRQ 457
Q E+++ + E EK+R +E +R+ E +E RE+Q+ R ++RERQ + Q
Sbjct: 1147 QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQ 1206
Query: 458 RKR 460
R++
Sbjct: 1207 RQK 1209
Score = 199 bits (506), Expect = 6e-51
Identities = 137/450 (30%), Positives = 248/450 (55%), Gaps = 24/450 (5%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
RR+ ++ ++ L Q + ++RE+ R +ERER Q E + ++E +
Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER-----QYREEEELQQEEEQLLGE 1066
Query: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
R+ R +E +R KE E Q + E+ + E E+ R++ERER+ E E ++ + +
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
Query: 148 ERERQRDAEKERERQTDRERQRQTER----NRQKEREREKNRQERRERERQREKENKTED 203
ERE++R E ER+ + + E Q++ E+ +K R +E RQ R E E Q+E+E +
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186
Query: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
+R +ERER+ E E +R+++ R RD ++++ + + + E+E A K RE
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 264 RERDRDRDRDRRQKERERQTDRKRQ--RRTERDRETERKRERQRERERERERNRKRERER 321
E+ R + D + ++R+ Q D + + ERDRE ER+R +QR+R E +RE ++
Sbjct: 1247 NEQFRQLE-DSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 322 ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE--RERERDR 379
E +R + +E ++ +ERE KR+RQ E +R+ E + ERE + R +ERDR
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQ-----ETDRKFREEEQLLQEREEQPLRRQERDR 1360
Query: 380 QSAREREERERDRDRD--RQKERERQTEKDRDGQRETEKQREREKDRESERGRERG-RER 436
+ RE E R +++ R +++R R+ E++R +E ++ R +E++++ + R+R RE
Sbjct: 1361 K-FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREE 1419
Query: 437 EKQKGR-ERDRERQTDRQAGRQRKRSTLYV 465
E+Q R ERDR+ + + Q R+++R ++
Sbjct: 1420 EQQLSRQERDRKFREEEQQVRRQERERKFL 1449
Score = 199 bits (505), Expect = 8e-51
Identities = 133/445 (29%), Positives = 240/445 (53%), Gaps = 23/445 (5%)
Query: 34 QESPRRRGLGQAHKDADG--DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKR 91
++ RR Q ++ DG +D+ER R +E +RR +K + + E +RKR R + +
Sbjct: 838 EQLQRRERAQQLQEEEDGLQEDQERRRSQE-QRRDQKWRWQLEEERKRRRHTLYAKPALQ 896
Query: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERER 151
++ R+ Q+ ++E E ER+++R +E+ RQ E + ++E E+ + + +R +ER
Sbjct: 897 EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER 956
Query: 152 QRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE 211
+R K+++ Q E+ E +++ +EREK +E E + Q E++ E+R R +E
Sbjct: 957 ERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ-QEEEQLLREEREKRRRQE 1015
Query: 212 RERE--RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
ER+ ++ E + E ++ ER+++R ERER+ + E E E E +ERE R ++
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075
Query: 270 RDRDRRQKERERQTDRK-------RQRRTERDRETERKRERQRERER----ERERNRKRE 318
+R R++E +Q + + ++RR ER+R+ + E Q+E E+ ERE+ R++E
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Query: 319 RERERERERERQRETERDREKERERKRKRQTEMD-RERNRQTGREGRRQAERERERERER 377
ER+ E E Q+E E+ +E E++R+++ E RE E + E + +R +ER
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
Query: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
+RQ REE E R + +Q+ R+ D Q E EK+ ++ +GRE + R+
Sbjct: 1196 ERQ---YREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
Query: 438 KQKGRERDRERQTDRQ--AGRQRKR 460
+ + RDR+ Q D Q G Q++R
Sbjct: 1253 LEDSQLRDRQSQQDLQHLLGEQQER 1277
Score = 198 bits (503), Expect = 1e-50
Identities = 136/469 (28%), Positives = 253/469 (53%), Gaps = 63/469 (13%)
Query: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDR 111
++R R K E E+RQ +++ + ERR+++ R +++R RE++ RE+E ER R
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER-REQRLKREEEEERLEQR 671
Query: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKE------RERQTDR 165
+ R+ E+ER Q+ E E E+ ER + R Q + E + DA + R+++ R
Sbjct: 672 LK-REHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQR 730
Query: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKT------EDRHSERGRER------- 212
RQ Q E+ R++E E + +ER R++Q E++ + + SERGR+R
Sbjct: 731 RRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL 790
Query: 213 --ERERETETETERKRQT-----DRERDRQRKTEREREKQAE----------RERASERE 255
+RER+ E ++R+ + E++++R+ REREK+ + RERA + +
Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
Query: 256 TERD---KERERERDRDRDRDRR-----QKERERQTD------------RKRQRRTERDR 295
E D +++ER R +++ RD++ ++ER+R+ RK Q+ + +
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
Query: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER 355
E ++ ER++ R +E+ER + E + ++E E+ + E E+ R +ERER+ ++ ++ ++
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
Query: 356 NRQTGREGRRQAERERERERERDRQSAREREERERD-RDRDRQKERERQTEKDRDGQRET 414
+ G E ++ +ERE++ + + +E E+ R+ R++ R++E ERQ K + Q+E
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE 1030
Query: 415 EK--QREREKDRESERGRERGREREKQKGRER--DRERQTDRQAGRQRK 459
E+ + EREK R ER R+ E E Q+ E+ ER+T R+ +R+
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1079
Score = 196 bits (497), Expect = 7e-50
Identities = 141/449 (31%), Positives = 251/449 (55%), Gaps = 33/449 (7%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
+E RRR + + + ER QKE +RR K Q E++ RE R EK R ++ DR
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL--LREEREEKRRRQETDR 1336
Query: 94 HRERQRDREKERERQTDR--ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERER 151
+ +ERE Q R ERDR+ +E R +E+ R+ E +R R ++ERER
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR------RQERER 1390
Query: 152 QRDAEKERERQTDRERQRQTERNRQ-KEREREKNRQERRERERQREKENKTEDRHSE-RG 209
+ E+++ R +RE+Q + +R+R+ +E E++ +RQER + R+ E++ + ++R +
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE 1450
Query: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
E++ +E + + Q +ER+ Q+ +ER+++ E R ERD++ + R
Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
Query: 270 RDRDRRQKERERQTDR-KRQRRTERDRETERKRERQRERERERERNRKRERERERERERE 328
++ +R+ E E+Q R +RQR+ ++ + R++ER ++R ++R+R + E + +ERE +
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ 1570
Query: 329 RQRETERDREKERERKRKRQTEMDR---ERNRQTGR-EGRRQAERERERERERDRQSARE 384
+ ERDR+ E ++ R+ E +R E +Q R EG++Q +ER+R+ D Q +E
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQE 1630
Query: 385 REERE---RDRDRD--------RQKERERQTEKDRDGQRETEKQREREKDRESERGRERG 433
REE++ ++RDR R++ERE+Q DRD + E+Q +E + + R +ER
Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690
Query: 434 RE--REKQKGRERDRER---QTDRQAGRQ 457
R+ E+Q+ R ++RER Q ++Q RQ
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQ 1719
Score = 192 bits (489), Expect = 6e-49
Identities = 132/458 (28%), Positives = 245/458 (53%), Gaps = 41/458 (8%)
Query: 42 LGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREKDRHRKRDRHRERQRD 100
L Q + G++RE R++E ER+ R++ + ++E ++ EK R ++R+R + +
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115
Query: 101 REKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERE 160
++E E+ ER+++R +E RQ E E ++E E+ + + +R +E +R +E E
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
Query: 161 RQTDRER-------QRQTERNRQKEREREKNRQERRERERQR------------EKENKT 201
Q + E+ +R+ ER RQ E E RQ+R++R R EKEN
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
Query: 202 EDRHSE-RGRERERERETETETERKRQTDRE--------RDRQRKTEREREKQAERERAS 252
D +GRE E+ R+ E R RQ+ ++ ++R R+ ER R +Q +R
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295
Query: 253 ERETERDKERE-RERDRDRDRDRRQKERERQTDRKRQRRTERDRETE---RKRERQRERE 308
E + ER++++E + RDR +++ ER+ R+RQ + RE E ++RE Q R
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 309 RERERNRKRERERERERERERQRETERDREKERERKRKRQTE----MDRERNRQTGREGR 364
+ER+R + E R +E+ R+ E +R R +ERERK ++ + +RE+ + R+ +
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 365 RQAERERERERERDRQSAREREERERDRDRDR---QKERERQTEKDRDGQRETEKQRERE 421
+ E ++ +ERDR+ RE E++ R ++R+R ++E++ + E+ R + E + +ERE
Sbjct: 1416 FREEEQQLSRQERDRK-FREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Query: 422 KDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
+ + + R+R E+Q+ R ++R+R+ Q R ++
Sbjct: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
Score = 191 bits (485), Expect = 2e-48
Identities = 151/530 (28%), Positives = 264/530 (49%), Gaps = 100/530 (18%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREK-- 85
R++ +E RR ++ + +R +++ E RRE+ E E ++ RER + +
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
Query: 86 ------------------DRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKER 127
R RK++ R RQ EK R R+++ + + R +Q+E
Sbjct: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
Query: 128 ER-------ETEREGERGRDRQTDG---QRERERQRDAEKERERQT-------DRERQRQ 170
+R + E + ERGR R + + +RERQ AE+ ++R+ ++E++R+
Sbjct: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR 822
Query: 171 TERNRQKERE--REKNRQERRERERQ--REKENKTEDRHSERGRERERER----ETETET 222
R R+KE + E+ + +RRER +Q E++ ED+ R +E+ R++ + E E
Sbjct: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER 882
Query: 223 ERKRQT--------------------------DRERDRQRKTEREREKQAERERASERET 256
+R+R T ER+++R+ E+ER+ + E + E E
Sbjct: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 257 ----ERDKERERERDRDRDRDRRQKERERQ---TDRKRQRRTERDRETERKRERQRERER 309
ER+K R +ER+R +D++ +++E Q + +++RR ER+++ + E Q+E E+
Sbjct: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
Query: 310 ----ERERNRKRERERERERERERQRETER----DREK----ERERKRKRQTEMDRERNR 357
ERE+ R++E ER+ ++ E Q+E E+ +REK ERER+ + + E+ +E +
Sbjct: 1003 LLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
Query: 358 QTG--REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETE 415
G RE RR+ E ER+ +E + Q E+ RE R RQ ERERQ ++ + Q+E E
Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ-ERERQCREEEELQQEEE 1121
Query: 416 K--QREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
+ + EREK R E R+ E E Q+ E Q R+ +R+R L
Sbjct: 1122 QLLREEREKRRRQELERQYREEEEVQQ-----EEEQLLREEPEKRRRQEL 1166
Score = 189 bits (481), Expect = 5e-48
Identities = 142/513 (27%), Positives = 262/513 (51%), Gaps = 80/513 (15%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDR------KRE 80
RR+ ++ L Q + ++RE+ R++E ER+ RE+ + ++E ++ ++
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 81 RRREKDRHRKRDRH---------RERQRDREKERERQTDRERDRQREKERNRQKERERET 131
RR+E +R + + RE Q R +ERERQ E + QR+K + R ++ ++ +
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Query: 132 E----------------------REGERGRDRQTDGQRERERQRDAE------KERERQT 163
+ RE E+ R + R+R+ Q+D + +ER+R+
Sbjct: 1222 DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQ 1281
Query: 164 DRERQRQTERNRQKEREREKNRQ---ERRERERQREKENKTEDRHSERGR---ERERERE 217
+R R +Q +R+ +E + E+ Q +RR+R+ Q EK+ E+R +R R +R+ E
Sbjct: 1282 ERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREE 1341
Query: 218 TETETERKRQTDRERDRQRK----------------TEREREKQAERERASERETERDKE 261
+ ER+ Q R ++R RK E +R ++ ERER +E ++ +
Sbjct: 1342 EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401
Query: 262 RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER 321
+ERE+ +DRDR+ +E E+Q R+ + R R+ E + +R+ + + E E+ ++ER R
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
Query: 322 ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERER---ERD 378
+ E + +E E + +ER RK E + R ++ R+ R Q R +E ER E +
Sbjct: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE 1521
Query: 379 RQSAREREERE--RDRDRDRQKERERQTEKDRDGQRETEKQ--REREKDRESERGRERGR 434
+Q R++ +R+ ++ + R++ER +Q +DRD + E+Q +ERE+ + S + R+R
Sbjct: 1522 QQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF 1581
Query: 435 EREKQKGRERDRER-------QTDRQAGRQRKR 460
E+QK R +++ER Q RQ G+Q+ R
Sbjct: 1582 RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR 1614
Score = 189 bits (479), Expect = 8e-48
Identities = 132/516 (25%), Positives = 264/516 (51%), Gaps = 79/516 (15%)
Query: 22 IPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKER--ERRREKRQTERETDRKR 79
+ L+ RR Q+ R + L + ++ +R ++ER +R R ++Q RE + +R
Sbjct: 489 LKLEEEERR--EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 80 ER--RREKDRHRKRDRHRER-QRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
E+ +RE+++ +++R +R +R++E+ R++ RE +R++++ + Q+ER + + E
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE 606
Query: 137 RGRDRQTDGQRERERQRDAEKERERQ------TDRERQRQTERNRQKEREREKNRQERRE 190
R Q + + +R ++ + E+ER +Q + RQ+Q R +Q+ RE+ R+E E
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 191 RERQREKENKTEDRHSERGRERERER--------------ETETETERKRQTDRERDRQR 236
R QR K E+R + E E+E+ + E+E + ++ R R++
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
Query: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRR----QKERERQTDRKRQR--- 289
+ +R R++Q E+ R E E + +E R + + RR Q + E +++R RQR
Sbjct: 727 EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786
Query: 290 ----RTERDRETERKRERQRER-----ERERERNRKRERERERE------------RERE 328
R +R+R+ + +QRE+ E E+E+ R++ RERE+E RER
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA 846
Query: 329 RQ-----------RETERDREKERERKRKRQTEMDRERNRQT-----------GREGRRQ 366
+Q +E R +E+ R++K + Q E +R+R R T +E +
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
Query: 367 AERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRES 426
E E E +RE + R+ +ER+ + Q+E E+ ++R+ +R E++R+ KD++
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 427 ERGRER--GREREKQKGRERDRERQTDRQAGRQRKR 460
++ E+ G E EK++ +ER+++ + + + ++ ++
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
Score = 188 bits (477), Expect = 1e-47
Identities = 148/529 (27%), Positives = 263/529 (49%), Gaps = 81/529 (15%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQT-ERETDRKRERRR 83
D+ +R ++ + R Q +D + + RER + E E RRE+++ E++ R++E RR
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR 515
Query: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDRQ----REKERNRQKERERETEREGERGR 139
E+ R+ + R +QR R +++ R+ ER Q E++R Q+ RE+ +RE E R
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN 199
D+ + ER +QR ++ ER R ++ + ER Q+ER ++ ++E E ER R++
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER-RQQLL 634
Query: 200 KTEDRHSERGRERERERETETETERKRQTDRERDRQR-KTEREREK------QAERERAS 252
K+E++ R ++ RE++ E KR+ + ER QR K E E E+ + E+E+A
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694
Query: 253 ER------------ETERD-----------KERERERDRDRDRDRRQKERE--------- 280
ER E+E D K+ + R ++++ RR++E E
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERA 754
Query: 281 -RQTDRKRQRRT-----ERDRETERKRER---------QRERE-RERERNRKRERERERE 324
RQ + QRR + + ++ER R+R QRER+ R ER ++ +R E
Sbjct: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEE 814
Query: 325 RERERQRETERDREKE------------RERKRKRQTEMD-------RERNRQTGREGRR 365
E+E++R R+REKE RER ++ Q E D R R+++ R+ +
Sbjct: 815 EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874
Query: 366 QAERERERERERDRQSARER-EERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424
+ + E ER+R R A+ +E+ R + Q+E E ++R+ +R E++R+ ++
Sbjct: 875 RWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE 934
Query: 425 ESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTAR 473
+ ++ E+ E++K R ++RERQ + Q+K L P + R
Sbjct: 935 QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983
Score = 184 bits (467), Expect = 2e-46
Identities = 139/504 (27%), Positives = 269/504 (53%), Gaps = 76/504 (15%)
Query: 35 ESPRRRGLGQAHKDADGDDRERNR--QKERERRREKRQTERETDRKRERRREKDRHRKRD 92
E RR+ L + +++ + +E + ++E+E+RR++R+ + + + +R++ K R+R D
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218
Query: 93 RHRE--------------------RQRDREKERERQTDRERDRQREKERNR----QKERE 128
+ + + R+ E+ R+ + + RDRQ +++ Q+ER+
Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278
Query: 129 RETEREGERGRDRQ--TDGQRERERQRDAEKERERQTDRERQ-----RQTERNRQ----K 177
RE ER + RDR + Q ERE Q++A K R+R++ E+Q R+ +R RQ K
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEA-KRRDRKSQEEKQLLREEREEKRRRQETDRK 1337
Query: 178 EREREKNRQERRE---RERQREKENKTED-RHSERGRE--------RERERETETETERK 225
RE E+ QER E R ++R+++ + E+ RH E+GR+ R +ERE + E +
Sbjct: 1338 FREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ 1397
Query: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
+ +ER++Q + +R+R+ + E ++ S +E +R E ++ R ++R+R+ E E+Q +
Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457
Query: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK- 344
+R R+ + + ++RE Q+ +ER+R E ++ R +ER+R+ + R +E ERK
Sbjct: 1458 ERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKF 1517
Query: 345 ---------RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREER-----ER 390
++RQ + +E + +E +Q ++R+R+ + Q +EREE+ ER
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
Query: 391 DR------DRDRQKERERQTEKDRDGQRETEKQRE--REKDRESERGRERGREREKQKGR 442
DR + R++E+ER+ +D R E Q++ +E+DR+ + +ERE+Q+
Sbjct: 1578 DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLH 1637
Query: 443 ERDRER---QTDRQAGRQRKRSTL 463
++R+R + + Q RQ + L
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQL 1661
Score = 183 bits (465), Expect = 3e-46
Identities = 135/467 (28%), Positives = 255/467 (54%), Gaps = 41/467 (8%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREKD 86
RR+ ++ + L Q + ++ E+ R++ERER+ RE+ + ++E ++ REK
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERG-RDRQTDG 145
R ++ +R + + ++E E+ E +++R +E RQ E E ++E E+ R+ Q
Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191
Query: 146 QRERERQRDAEKERERQTDRERQRQTERNR----QKEREREKNRQER------RERERQR 195
++ERERQ E+E +RQ ++R R ++ Q E E+E ++ RE E+ R
Sbjct: 1192 RQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Query: 196 EKEN-KTEDRHSER------GRERERERETETETERKRQTDRERDRQRKTEREREKQAE- 247
+ E+ + DR S++ G ++ER+R E E R +Q DR + + ERE +K+A+
Sbjct: 1252 QLEDSQLRDRQSQQDLQHLLGEQQERDR--EQERRRWQQRDRHFPEEEQLEREEQKEAKR 1309
Query: 248 RERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ---RRTERDRETERKRERQ 304
R+R S+ E + +E E+ R ++ DR+ +E E+ + + RR ERDR+ + R
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH 1369
Query: 305 RERER----ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
+E+ R E +R R++ERER+ +E ++ R ER+++ ++R RK + E + ++
Sbjct: 1370 QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429
Query: 361 REGRRQAERERERERER-----DRQSAREREERERDRD---RDRQKERERQTEKDRDGQR 412
R+ R + ++ R +ERER ++Q +ER + R+ + ++R++++ + E+DR
Sbjct: 1430 RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLE 1489
Query: 413 ETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
E ++ R +E+DR+ R +E E+ + + E+Q RQ RQRK
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPER---KFLEEEQQLHRQQ-RQRK 1532
Score = 183 bits (464), Expect = 4e-46
Identities = 133/453 (29%), Positives = 254/453 (56%), Gaps = 40/453 (8%)
Query: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRR---EKDRHRKRDRHR----E 96
Q +D D RE +Q R+ R K + E + R++ER R E+++ +++RHR E
Sbjct: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
Query: 97 RQRDREKERERQTDRERDRQ--REKERNRQKERERETEREGERGRD--------RQTDGQ 146
Q +E+E ++ +ERDR+ E+++ R++ER+R+ + R ++ Q +
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206
++R+R+ E+++ R+ +R +QR+ +R+R K RE E+ RQER E++ R++ ++
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDR-KFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
Query: 207 ERGRERERERE-TETETERKRQTDRERDRQRKTEREREKQ---AERERASERETERDK-- 260
++ R +E+ER+ E E + +RQ +++ RQ + + RE + ERE ERD+
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
Query: 261 ----------ERERERDRDRDRDRRQKERERQTDRKRQ-RRTERDRETERKRERQRERER 309
ERE++ DRDR R++E+ Q ++Q RR ERDR+ + ++ R +ER
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 310 ERERNRKRERERERERERERQRETERDREKERE--RKRKRQTEMDRERNRQTGREGRRQA 367
ER+ ++ ++ R +E ER+ + E + +E E+E R+++R ++ E + RE ++
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
Query: 368 ERERERERERDRQSAREREERE-RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRES 426
+ER+R+ + Q +EREE++ R ++ DR+ E Q ++R+ Q+ +QR+ + E
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825
Query: 427 ERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
E + + E+E++ +ERDR+ + + Q Q K
Sbjct: 1826 E--QLQLEEQEQRLRQERDRQYRAEEQFATQEK 1856
Score = 179 bits (454), Expect = 6e-45
Identities = 122/453 (26%), Positives = 245/453 (54%), Gaps = 29/453 (6%)
Query: 29 RRPGSQESPRRRGLGQAHKDADG-DDRERNRQKERER-----------RREKRQTERETD 76
R+ +E +R+ Q ++D D D + + E+E R ++ + E
Sbjct: 1197 RQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDS 1256
Query: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
+ R+R+ ++D +ER R++E+ R +Q DR + + ER QKE +R
Sbjct: 1257 QLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR------- 1309
Query: 137 RGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196
RDR++ +++ R+ EK R ++TDR + R+ E+ Q+ E+ RQER + R+ E
Sbjct: 1310 --RDRKSQEEKQLLREEREEKRRRQETDR-KFREEEQLLQEREEQPLRRQERDRKFREEE 1366
Query: 197 KENKTEDRH--SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254
++ + R E R R +ERE + E ++ +ER++Q + +R+R+ + E ++ S +
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ 1426
Query: 255 ETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERN 314
E +R E ++ R ++R+R+ E E+Q ++R R+ + + ++RE Q+ +ER+R
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
Query: 315 RKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
E ++ R +ER+R+ + R +E ERK + + + RQ R+ ++ ++ R +E
Sbjct: 1487 FLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ--RKFLQEEQQLRRQE 1544
Query: 375 RERDRQSAREREERERDRDR-DRQKERERQTEKDRDGQRETEKQREREKDRE--SERGRE 431
R + R+ R+R+ RE ++ R +R++++ + E+DR + E +K R +E++R+ + +
Sbjct: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQL 1604
Query: 432 RGREREKQKGRERDRERQTDRQAGRQRKRSTLY 464
R +E ++Q +ERDR+ + D Q ++R+ L+
Sbjct: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLH 1637
Score = 177 bits (448), Expect = 3e-44
Identities = 138/527 (26%), Positives = 263/527 (49%), Gaps = 76/527 (14%)
Query: 23 PLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR--REKRQTERETDRKRE 80
P + R +E+ RR Q K ++RE R+++ R RE+ Q +E + +
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPL 1353
Query: 81 RRREKDRHRKRD--RHRER--------QRDREKERERQTDRERDRQREKERNRQKERERE 130
RR+E+DR + + RH+E+ QR R +ERER+ +E + R +ER +Q ++R+
Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413
Query: 131 TE-REGERGRDRQTDGQRERERQRDAEK-ERERQTDRERQRQTERNRQKEREREKNRQER 188
+ RE E+ RQ ++ RE ++ + ERER+ E Q+ + +K RE E+ QER
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473
Query: 189 RERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE----------RDRQRKT 238
E++ R++ ++ ++ R +ER+R+ + R ++ +R+ + RQRK
Sbjct: 1474 EEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533
Query: 239 EREREKQAERERASERETERDK----------ERERERDRDRDRDRR-----QKERERQT 283
+E ++ +ER +R +RD+ ERE ++ ++RDR+ QK R ++
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 284 DRK--------------RQRRTERDRETE------RKRERQRERERERERNRKRERERER 323
+RK +Q R ERDR+ ++RE Q+ +ER+R E + R
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 324 ERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERD----- 378
+ERE+Q +RDR+ E + ++ E + R ++ R+ R + ++ R +ERER
Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE 1713
Query: 379 ------------RQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRES 426
R+ + R+E E+++ R +++ R+ E+ +RE ++ R +E+DR+
Sbjct: 1714 QQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKF 1773
Query: 427 ERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTAR 473
+ +ERE+Q+ R ++ +R+ + +++R + P R +
Sbjct: 1774 REEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
Score = 176 bits (445), Expect = 7e-44
Identities = 128/474 (27%), Positives = 240/474 (50%), Gaps = 70/474 (14%)
Query: 54 RERNRQKERERRREKRQTERETDR----KRERRREKDRHRKRDRHRERQRDREKERERQT 109
RE ++ E+ERR ++ + E+E R KRE R + R ++ R QR + +E ER
Sbjct: 552 REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLE 611
Query: 110 DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQR 169
ER QR K ++ER ++ + E+ RQ +RE++ +R+ +RE + +R QR
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR 671
Query: 170 QTERNRQKEREREKNRQERRERERQREK----------ENKTEDRHSE---RGRERERER 216
+R ++ER ++ +E +E+ R+R K E++ + R S+ R R++E +R
Sbjct: 672 -LKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQR 730
Query: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERAS---ERETERDKERERERDRDRDRD 273
+ + E++R+ + E Q + R++Q E +R + + E ER R+R R
Sbjct: 731 RRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL 790
Query: 274 RRQKERERQTDRKRQRRTE---RDRETERKRERQRERERE------------RER----- 313
R Q+ER+ + + ++QR + E E++R ++RERE+E RER
Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
Query: 314 --------NRKRERERERERERERQRETERDREKERE------------RKRKRQTEMDR 353
+++R R +E+ R+++ + + E +R++ R RK ++ + +
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
Query: 354 ERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR- 412
E ++ RE RR+ E+ER+ E Q E+ RE +R++ R++ERERQ KD+ Q+
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE-EREKRRRQERERQYRKDKKLQQK 969
Query: 413 -------ETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
E EK+R +E++++ E +E E+ ER++ R+ + + ++K
Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
Score = 174 bits (442), Expect = 2e-43
Identities = 124/459 (27%), Positives = 247/459 (53%), Gaps = 32/459 (6%)
Query: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRH--RERQRDREKERERQT 109
++++ +RQ+ + E+ Q R +R R+ R ++ R ++ +R E Q+ ++R+R+
Sbjct: 1474 EEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533
Query: 110 DRERDRQREKERNRQKERERETE-REGERGRDRQTDGQRER-ERQRDAEKERERQTDRER 167
+E + R +ER +Q+ ++R+ + RE E+ R + + Q R ER R E ++ +E+
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 168 QRQTERNRQKEREREKNRQERRERERQ-REKENKTEDRHSERGRERERERE-TETETERK 225
+R+ + Q+ R +E +Q R+ER+R+ RE E ++R ++ +ER+R+ E E + +
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERD-RDRDRDRRQKERERQTD 284
RQ ER++Q + +R+R+ + E + E E ++ + +ER+R R+ ++ R++ERER+
Sbjct: 1654 RQ---EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710
Query: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERE--------RERERERQRETERD 336
++ Q+ ++ E + + E Q +E E+E+ R++ER R+ ERE ++ R ERD
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 337 REKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAR------------- 383
R+ E + +++ E + R++++ R+ R + + +ERE ++ R R
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830
Query: 384 EREERERDRDRDRQKERERQ-TEKDRDGQRETEKQREREKDRESERGRERGREREKQKGR 442
E +E+ ++RDRQ E Q +++ + E E +E E+ R ER R+ E +++ +
Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
Query: 443 ERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDP 481
E R RQ ++ K + P S V+S P
Sbjct: 1891 EEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSP 1929
Score = 153 bits (387), Expect = 4e-37
Identities = 107/388 (27%), Positives = 227/388 (58%), Gaps = 23/388 (5%)
Query: 38 RRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREKDRHRKRDRHRE 96
R+R Q + +R + R+++R+R+ RE+ Q +E + ++ R+E+DR + + +
Sbjct: 1529 RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKV 1588
Query: 97 RQRDREKERERQTDRERDRQREKERNRQKERERETEREGE--RGRDRQTDGQRERERQRD 154
R++ E+ER+ D ++ R++E ++ ++ER+R+ + + + R+ Q ++ER+R+
Sbjct: 1589 RRQ--EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFL 1646
Query: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER 214
E+ + R+ +RE+Q + +R+R K RE E+ QE E++ +R++ ++ ++ R +ER
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDR-KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 215 ERETETETERKRQTDRER------DRQRKTEREREKQAERERASERETERDKERERERDR 268
ER+ E ++ R+ + ER +++TE+E+ ++ ER R E + ERE ++ R
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
Query: 269 DRDRDRRQKERERQTDRKRQRRTERDRETERK--RERQRERERERERNRKRERERERERE 326
++RDR+ +E E Q ++R+ + R +E++RK E Q +ERE ++ R ++R+ + E
Sbjct: 1766 RQERDRKFREEE-QLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE 1824
Query: 327 RERQRETERDREKERERKRKRQTEMD---RERNRQTGREGRRQAERERERERERDRQSAR 383
E+ + E+++ +ER R+ + E +E++R+ +E ++ E++R +ERER +
Sbjct: 1825 EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERER-----K 1879
Query: 384 EREERERDRDRDRQKERERQTEKDRDGQ 411
REE R + ++ Q+ R+ K ++G+
Sbjct: 1880 LREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Score = 123 bits (309), Expect = 4e-28
Identities = 79/302 (26%), Positives = 169/302 (55%), Gaps = 12/302 (3%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
RR+ G Q+ + R + ++ + +ER Q+ + R+++ E E +R+ R ++ R
Sbjct: 1605 RRQEGQQQLRQERD--RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Query: 88 HRKRDRHRERQR---DREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
H + + RE ++ + E+++ R+ +R+R + E+++ R++ERER+ +E ++ R ++ +
Sbjct: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE 1722
Query: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
+ E Q E E+E+ +ER R+ Q ERE+ Q+ R +ER R+ + + R
Sbjct: 1723 RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREE--QQLRRQERDRKFREEEQLR 1780
Query: 205 HSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERER 264
+ERE ++ E++RK + + + ++R+ ++ R +Q + + E E + +E+E+
Sbjct: 1781 -----QEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835
Query: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERE 324
++RDR R +E+ ++ R+ E +E E+KR ++RER+ E R++++E +R
Sbjct: 1836 RLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRH 1895
Query: 325 RE 326
R+
Sbjct: 1896 RQ 1897
Score = 110 bits (276), Expect = 3e-24
Identities = 73/278 (26%), Positives = 142/278 (51%), Gaps = 23/278 (8%)
Query: 187 ERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA 246
+ +R R KE+ +DR E + R R+ + E E +R RQ++ E+ERE A
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEE-----PGQRRRQKRQEQEREL-A 149
Query: 247 ERERASERETERDKERERERDRDRDRDRRQ-KERERQTDRKRQRRTERDRETERKRERQR 305
E E SE++ ++ + RD + R R++ +ERE + + Q ++ + ETE + ++
Sbjct: 150 EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209
Query: 306 ERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRR 365
R RE R++ RE ++++ RERQ ++ E++ RKR+ + E+ ++ + +R
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 366 QAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE 425
+ + E E+ R+ +RQ R RERQ E+ + + E+Q R+++ E
Sbjct: 270 ELQEEEEQLRKLERQELR----------------RERQEEEQQQQRLRREQQLRRKQEEE 313
Query: 426 SERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
+E RE+++++ ++ +R Q R+ +R+ L
Sbjct: 314 RREQQEERREQQERREQQEERREQQLRREQEERREQQL 351
Score = 50.1 bits (118), Expect = 6e-06
Identities = 30/135 (22%), Positives = 69/135 (51%), Gaps = 1/135 (0%)
Query: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88
R+ +E R+ Q + + D + R ++ R+ R E++ ++ D K E+ +
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830
Query: 89 RKRDRHRERQRDREKERERQ-TDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
++++ ++RDR+ E Q +E+ R+ E+E +++E++R ERE + + Q+
Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
Query: 148 ERERQRDAEKERERQ 162
E +R R + + ++
Sbjct: 1891 EEQRHRQVGEIKSQE 1905
Score = 38.1 bits (87), Expect = 0.023
Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 21/102 (20%)
Query: 363 GRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREK 422
G + +R R +E Q R+ E++ R RDRQ E E GQR +K++E+E
Sbjct: 94 GLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEE-------PGQRRRQKRQEQE- 145
Query: 423 DRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLY 464
RE +G E+ +++ Q RQR+ L+
Sbjct: 146 -------------RELAEGEEQSEKQERLEQRDRQRRDEELW 174
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 208 bits (530), Expect = 1e-53
Identities = 105/203 (51%), Positives = 148/203 (72%), Gaps = 8/203 (3%)
Query: 56 RNRQKERERRREKRQTERETDRKRERRRE---KDRH----RKRDRHRERQRDREKERERQ 108
R+ E E +R+ RETDR+R+R +E +DRH R+RDR R R+RDR++ERE+Q
Sbjct: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQ 67
Query: 109 TDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
TDRE +RQRE+ER+R ++RE E ER+ ER DR T+ RER++Q++ E ER R +RE+Q
Sbjct: 68 TDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQ 127
Query: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETET-ERKRQ 227
++ R RQ +RE ++ R+ + ERER+ +E KTEDRH ER RER+RERE + ET ER+R
Sbjct: 128 KEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERH 187
Query: 228 TDRERDRQRKTEREREKQAERER 250
TD ER+RQR+T+R+R++Q E ER
Sbjct: 188 TDMERERQRETDRKRDRQRESER 210
Score = 204 bits (518), Expect = 2e-52
Identities = 111/250 (44%), Positives = 170/250 (68%), Gaps = 38/250 (15%)
Query: 198 ENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257
E+KTE RH+ TETET DR+R+R+R+T+RER++ A+ + +R +E
Sbjct: 2 ESKTEGRHTH----------TETET-----MDRQRERRRETDRERDR-AKESKTEDRHSE 45
Query: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
RD++R+RER+R+RDRDR ER+++T+R+ ERQRERER+R+R R+
Sbjct: 46 RDRQRDRERNRERDRDR-----------------EREKQTDREGERQRERERDRDRQRET 88
Query: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER 377
ERER++ERE +R ET+R+R+K++ER+ +R + +RE+ ++ GRE RQ +RE +RERE
Sbjct: 89 ERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRE--RQTDRETDRERE- 145
Query: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
RQ+ RERE + DR +ERER+ +++R+ +RET K+RER D E ER RE R+R+
Sbjct: 146 -RQAERERETGRERKTEDRHRERERERKRERERKRET-KERERHTDMERERQRETDRKRD 203
Query: 438 KQKGRERDRE 447
+Q+ ER+R+
Sbjct: 204 RQRESERERD 213
Score = 203 bits (517), Expect = 3e-52
Identities = 112/226 (49%), Positives = 158/226 (69%), Gaps = 24/226 (10%)
Query: 91 RDRHRERQR-DREKERERQTDRERDRQRE-KERNRQKERERETEREGERGRDRQTDGQRE 148
R H E + DR++ER R+TDRERDR +E K +R ER+R+ +RE R RDR D +RE
Sbjct: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR--DRERE 65
Query: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
++ R+ E++RER+ DR+RQR+TER R KERE +++ + RER++Q+E+E +
Sbjct: 66 KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREME-------- 117
Query: 209 GRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDR 268
R R+RERE + E R+RQTDRE DR+R+ + ERE++ RER +E D+ RERER+R
Sbjct: 118 -RVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTE-----DRHRERERER 171
Query: 269 DRDRDRRQ--KERERQTDRKRQRRTERDRETERKRERQRERERERE 312
R+R+R++ KERER TD +R ER RET+RKR+RQRE ERER+
Sbjct: 172 KRERERKRETKERERHTDMER----ERQRETDRKRDRQRESERERD 213
Score = 200 bits (509), Expect = 3e-51
Identities = 109/212 (51%), Positives = 156/212 (73%), Gaps = 17/212 (8%)
Query: 164 DRERQRQTERNRQKEREREKNRQERR-ERERQREKENKTEDRHSERGRERERERETETET 222
DR+R+R+ E +R+++R +E ++R ER+RQR++E R+ ER R+RERE++T+ E
Sbjct: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRE-----RNRERDRDREREKQTDREG 72
Query: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
ER+R+ +R+RDRQR+TERER+K+ E +R +E + ER K++ERE +R RDR ERE+Q
Sbjct: 73 ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR-----EREKQ 127
Query: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342
+ R+R+T DRET+R+RERQ ERERE R RK E +R RERERER+RE ER RE
Sbjct: 128 KEMGRERQT--DRETDRERERQAERERETGRERKTE-DRHRERERERKRERERKRE---T 181
Query: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERE 374
++R+R T+M+RER R+T R+ RQ E ERER+
Sbjct: 182 KERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 197 bits (502), Expect = 2e-50
Identities = 119/231 (51%), Positives = 161/231 (69%), Gaps = 29/231 (12%)
Query: 165 RERQRQTER-NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER--ETETE 221
R +TE +RQ+ER RE +RER R KE+KTEDRHSER R+R+RER E + +
Sbjct: 8 RHTHTETETMDRQRERRRET------DRERDRAKESKTEDRHSERDRQRDRERNRERDRD 61
Query: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER 281
ER++QTDRE +RQR+ ER+R++Q E ER ERDKERE +R + DR+R QK++ER
Sbjct: 62 REREKQTDREGERQRERERDRDRQRETER------ERDKERETDRHTETDRER-QKQKER 114
Query: 282 QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
+ +R R DRE E+++E RER+ +RE +R+RER+ ERERE R+R+TE DR +ER
Sbjct: 115 EMERVR------DREREKQKEMGRERQTDRETDRERERQAERERETGRERKTE-DRHRER 167
Query: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE-ERERD 391
ER+RKR +RER R+T +E R + ERER+RE DR+ R+RE ERERD
Sbjct: 168 ERERKR----ERERKRET-KERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 195 bits (496), Expect = 9e-50
Identities = 107/252 (42%), Positives = 164/252 (65%), Gaps = 41/252 (16%)
Query: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDR 165
E +T+ + +RQ+ER RET+RE +R ++ +T+ +R ++R
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTE---------------DRHSER 46
Query: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
+RQR ERNR+++R+RE+ +Q RE ERQRE+E R+R+R+RETE
Sbjct: 47 DRQRDRERNRERDRDREREKQTDREGERQRERE-----------RDRDRQRETE------ 89
Query: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
RERD++R+T+R E ER++ ERE ER ++RERE+ ++ R+R + +R+TDR
Sbjct: 90 ----RERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRER---QTDRETDR 142
Query: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERE-RERERQRETERDREKERERK 344
+R+R+ ER+RET R+R+ + +R RERER RKRERER+RE +ERER + ER+R++E +RK
Sbjct: 143 ERERQAERERETGRERKTE-DRHRERERERKRERERKRETKERERHTDMERERQRETDRK 201
Query: 345 RKRQTEMDRERN 356
R RQ E +RER+
Sbjct: 202 RDRQRESERERD 213
Score = 192 bits (487), Expect = 1e-48
Identities = 108/218 (49%), Positives = 151/218 (69%), Gaps = 16/218 (7%)
Query: 244 KQAERERASERET-ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
K R +E ET +R +ER RE DR+RDR + K +R ++R RQR + ER RE
Sbjct: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQR------DRERNRE 57
Query: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGRE 362
R R+RERE++ +R+ ER+RERER+R+RQRETER+R+KERE R TE DRER +Q RE
Sbjct: 58 RDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDR--HTETDRERQKQKERE 115
Query: 363 GRRQAERERERERERDRQSARERE-ERERDRDRDRQKERERQTEKDRDGQRETEKQRERE 421
ER R+RERE+ ++ RER+ +RE DR+R+RQ ERER+T ++R + + ++RERE
Sbjct: 116 ----MERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTE-DRHRERERE 170
Query: 422 KDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
+ RE ER RE +ERE+ ER+R+R+TDR+ RQR+
Sbjct: 171 RKRERERKRET-KERERHTDMERERQRETDRKRDRQRE 207
Score = 181 bits (458), Expect = 2e-45
Identities = 99/219 (45%), Positives = 149/219 (68%), Gaps = 27/219 (12%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK---RQTERETDRKRERRRE 84
R+R +E+ R R + K D ER+RQ++RER RE+ R+ E++TDR+ ER+RE
Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHS-ERDRQRDRERNRERDRDREREKQTDREGERQRE 77
Query: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
++R R R R ER+RD+E+E +R T+ +R+RQ++KER ++ R+RE E++ E GR+RQTD
Sbjct: 78 RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTD 137
Query: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
+ +RER+R A ERER+T RER+ + +R +ERERE R+RER+R++E K +R
Sbjct: 138 RETDRERERQA--ERERETGRERKTE---DRHRERERE------RKRERERKRETKERER 186
Query: 205 HSERGRERERERETETETERKRQTDRERDRQRKTERERE 243
H T+ E ER+R+TDR+RDRQR++ERER+
Sbjct: 187 H------------TDMERERQRETDRKRDRQRESERERD 213
Score = 154 bits (390), Expect = 2e-37
Identities = 89/186 (47%), Positives = 129/186 (69%), Gaps = 24/186 (12%)
Query: 289 RRTERDRET-ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
R T + ET +R+RER+RE +RER+R ++ + E +R ER+RQR+ ER+RE++R
Sbjct: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTE-DRHSERDRQRDRERNRERDR------ 60
Query: 348 QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR----DRDRQKERERQ 403
DRER +QT REG RQ ERER+R+R+R+ + R++E RE DR DR+RQK++ER+
Sbjct: 61 ----DREREKQTDREGERQRERERDRDRQRETERERDKE-RETDRHTETDRERQKQKERE 115
Query: 404 TEKDRDGQRETEKQ--REREKDRESERGRERGREREKQKGRE-----RDRERQTDRQAGR 456
E+ RD +RE +K+ RER+ DRE++R RER ERE++ GRE R RER+ +R+ R
Sbjct: 116 MERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRER 175
Query: 457 QRKRST 462
+RKR T
Sbjct: 176 ERKRET 181
Score = 143 bits (360), Expect = 5e-34
Identities = 79/179 (44%), Positives = 118/179 (65%), Gaps = 13/179 (7%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
D R ++ R R + + DRE RQ+ERER R++ +RET+R+R++ RE
Sbjct: 41 DRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDR---QRETERERDKERE 97
Query: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQ------KERERETEREGERG 138
DRH + DR R++Q++RE ER R DRER++Q+E R RQ +ERER+ ERE E G
Sbjct: 98 TDRHTETDRERQKQKEREMERVR--DREREKQKEMGRERQTDRETDRERERQAERERETG 155
Query: 139 RDRQT-DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196
R+R+T D RERER+R E+ER+R+T +ER+R T+ R+++RE ++ R +RE ER+R+
Sbjct: 156 RERKTEDRHRERERERKRERERKRET-KERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 139 bits (350), Expect = 7e-33
Identities = 74/164 (45%), Positives = 109/164 (66%), Gaps = 16/164 (9%)
Query: 298 ERKRERQRERERERERNRKRERERERERERERQRETE-RDREKERERKRKRQTEMDRERN 356
E K E + +R+RER RE +RER+R +E++ DR ER+R+R DRERN
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQR------DRERN 55
Query: 357 RQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEK 416
R+ +R+RERE++ DR+ R+RE RERDRDR R+ ERER E++ D ET++
Sbjct: 56 RER--------DRDREREKQTDREGERQRE-RERDRDRQRETERERDKERETDRHTETDR 106
Query: 417 QREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
+R+++K+RE ER R+R RE++K+ GRER +R+TDR+ RQ +R
Sbjct: 107 ERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAER 150
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 206 bits (525), Expect = 4e-53
Identities = 102/211 (48%), Positives = 159/211 (75%), Gaps = 17/211 (8%)
Query: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
ER+RE++ E +R E E ERD++RERE +R+ RQ++R R+ DR+ T+R++E E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQ----TDREKERE 57
Query: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
R++ER R+R+RERE R+ ER+RER+R+RER+R+T+R+R+K+R+R+RKR+T+ +RERNR+
Sbjct: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
Query: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQR 418
GRE +Q ERER+RERER RQ R+R+RQ++RER+ E DR+ QR E++
Sbjct: 118 GGRERDKQTERERDRERERQRQ-----------RERERQRQRERKRETDRERQRWAERE- 165
Query: 419 EREKDRESERGRERGREREKQKGRERDRERQ 449
ER+K+R+ ER +ER +E++K++ R D++R+
Sbjct: 166 ERKKERKKERKKER-KEKKKEEKRREDKKRK 195
Score = 205 bits (522), Expect = 8e-53
Identities = 110/226 (48%), Positives = 160/226 (70%), Gaps = 32/226 (14%)
Query: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER 161
E++RER+ + +R ++ E+ER+RQ+ERE +TERE R RQ D RER+RQ D EKERER
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTEREN---RHRQRDRHRERDRQTDREKERER 58
Query: 162 QTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETE 221
Q +R+RQRQ ER ++E ER++ RQ +RER+RQ ++E R+++R+RE
Sbjct: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRE-----------RDKDRDRE---- 103
Query: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER 281
RKR+TDR R+R RK RER+KQ ER ERD+ERER+R R+R+R +RQ+ER+R
Sbjct: 104 --RKRETDRNRERNRKGGRERDKQTER--------ERDRERERQRQRERER-QRQRERKR 152
Query: 282 QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER 327
+TDR+RQR ER+ ERK+ER++ER++ER+ +K E+ RE ++ +
Sbjct: 153 ETDRERQRWAERE---ERKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 202 bits (515), Expect = 5e-52
Identities = 99/201 (49%), Positives = 148/201 (73%), Gaps = 4/201 (1%)
Query: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETE 223
+R+R+R+ E +R KE ERE++RQ RE + +RE ++ DRH ER R+ +RE+E E + E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 224 RKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQT 283
R RQ RER+ +R+TER+RE+Q +RER + + ERDK+R+RER R+ DR+R ER R+
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR---ERNRKG 118
Query: 284 DRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER-QRETERDREKERE 342
R+R ++TER+R+ ER+R+RQRERER+R+R RKRE +RER+R ER +R+ ER +E+++E
Sbjct: 119 GRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
Query: 343 RKRKRQTEMDRERNRQTGREG 363
RK K++ E RE ++ EG
Sbjct: 179 RKEKKKEEKRREDKKRKWGEG 199
Score = 200 bits (509), Expect = 3e-51
Identities = 103/207 (49%), Positives = 153/207 (73%), Gaps = 13/207 (6%)
Query: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272
ER+RE + ET+R ++T+RERDRQR ERE Q ERE R +RD+ RER+R DR++
Sbjct: 2 ERQRERKRETDRGKETERERDRQR----ERENQTEREN---RHRQRDRHRERDRQTDREK 54
Query: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE 332
+R ER+++ DR+RQR E +RETER+RERQR+RER+R+ +R+R+++R+RER+RE R
Sbjct: 55 ER---ERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRN 111
Query: 333 TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392
ER+R+ RER ++ + E DRER RQ RE RQ +RER+RE +R+RQ EREER+++R
Sbjct: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKER 171
Query: 393 DRDRQKERERQTEKDRDGQRETEKQRE 419
++R+KER+ EK ++ +R +K+R+
Sbjct: 172 KKERKKERK---EKKKEEKRREDKKRK 195
Score = 198 bits (504), Expect = 1e-50
Identities = 109/228 (47%), Positives = 162/228 (71%), Gaps = 34/228 (14%)
Query: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
ER R+++RE R K +TERE DR+RER + +R +R RQRDR +ER+RQTDRE++
Sbjct: 2 ERQRERKRETDRGK-ETERERDRQRERENQTERE-----NRHRQRDRHRERDRQTDREKE 55
Query: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
R+R+KER+RQ++RERETERE ER R+R QR+RER+R ++ER++ DRER+R+T+RN
Sbjct: 56 RERQKERDRQRQRERETERETERQRER----QRQRERKRQTDRERDKDRDRERKRETDRN 111
Query: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
RE+NR+ RER++Q E+E DR ER R+RERER+ R+R+R
Sbjct: 112 ------RERNRKGGRERDKQTERE---RDRERERQRQRERERQ------------RQRER 150
Query: 235 QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
+R+T+RER++ AERE ER+ ER KER++ER + ++R+++++R+
Sbjct: 151 KRETDRERQRWAERE---ERKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 197 bits (501), Expect = 2e-50
Identities = 103/218 (47%), Positives = 161/218 (73%), Gaps = 22/218 (10%)
Query: 134 EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
E +R R R+TD +E ER+RD ++ERE QT+RE R+RQ++R RE++RQ RE+ER
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTEREN-----RHRQRDRHRERDRQTDREKER 56
Query: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
+R+KE R R+R+RERETE ETER+R+ R+R+R+R+T+RER+K +RER +
Sbjct: 57 ERQKE---------RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRER--K 105
Query: 254 RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER 313
RET+R++ER R+ R+RD K+ ER+ DR+R+R+ +R+RE +R+RER+RE +RER+R
Sbjct: 106 RETDRNRERNRKGGRERD-----KQTERERDRERERQRQRERERQRQRERKRETDRERQR 160
Query: 314 NRKR-ERERERERERERQRETERDREKERERKRKRQTE 350
+R ER++ER++ER+++R+ ++ EK RE K+++ E
Sbjct: 161 WAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
Score = 197 bits (501), Expect = 2e-50
Identities = 96/194 (49%), Positives = 149/194 (76%), Gaps = 3/194 (1%)
Query: 210 RERERERETETETERKRQTDRERDRQRKTERE-REKQAERERASERETERDKERERERDR 268
R+RER+RET+ E +R+ DR+R+R+ +TERE R +Q +R R +R+T+R+KERER+++R
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
Query: 269 DRDRDR-RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER 327
DR R R R+ ERE + R+RQR+ ER R+T+R+R++ R+RER+RE +R RER R+ RER
Sbjct: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
Query: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
++Q E ERDRE+ER+R+R+R+ + RER R+T RE +R AERE ER++ER ++ +ER+E
Sbjct: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE-ERKKERKKERKKERKE 181
Query: 388 RERDRDRDRQKERE 401
++++ R K+R+
Sbjct: 182 KKKEEKRREDKKRK 195
Score = 195 bits (495), Expect = 1e-49
Identities = 104/223 (46%), Positives = 157/223 (70%), Gaps = 30/223 (13%)
Query: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
ER R+++RE ++ ++ RER+RQRE+EN+TE + R R+R RER+ RQTDRE
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERD--------RQTDRE 53
Query: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
++R+R+ ER+R++Q ERE +ERETER +ER+R+R+R R DR ER++ DR+R+R T
Sbjct: 54 KERERQKERDRQRQRERE--TERETERQRERQRQRERKRQTDR---ERDKDRDRERKRET 108
Query: 292 ERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEM 351
+R+RE RK R+R+++ ERER+R+RER+R+RERER+RQRE RKR+T
Sbjct: 109 DRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRE------------RKRET-- 154
Query: 352 DRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDR 394
DRER R RE R+ +ER++ER+++R+ ++ E+R D+ R
Sbjct: 155 DRERQRWAEREERK---KERKKERKKERKEKKKEEKRREDKKR 194
Score = 188 bits (477), Expect = 1e-47
Identities = 94/200 (47%), Positives = 150/200 (75%), Gaps = 13/200 (6%)
Query: 95 RERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRD 154
R+R+R RE +R ++T+RERDRQRE+E ++E R +R+ R RDRQTD ++ERERQ+
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTEREN-RHRQRDRHRERDRQTDREKERERQK- 60
Query: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE-DRHSERGRERE 213
E++R+RQ +RE +R+TER R+++R+RE+ RQ RER++ R++E K E DR+ ER R+
Sbjct: 61 -ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER-----DKERERERDR 268
RER+ +TE ER DRER+RQR+ ERER++Q ER+R ++RE +R ++++ER+++R
Sbjct: 120 RERDKQTERER----DRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKER 175
Query: 269 DRDRDRRQKERERQTDRKRQ 288
++R ++KE +R+ D+KR+
Sbjct: 176 KKERKEKKKEEKRREDKKRK 195
Score = 186 bits (473), Expect = 4e-47
Identities = 99/213 (46%), Positives = 153/213 (71%), Gaps = 24/213 (11%)
Query: 247 ERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
ER+R +RET+R KE ERERDR Q+ERE QT+R+ R R+ +R RER R+
Sbjct: 2 ERQRERKRETDRGKETERERDR-------QRERENQTEREN-----RHRQRDRHRERDRQ 49
Query: 307 RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQ 366
+RE+ER R++ER+R+R+RERE +RETER RE++R+R+RKRQT+ +R+++R R+
Sbjct: 50 TDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRD------RE 103
Query: 367 AERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRES 426
+RE +R RER+R+ RER+ ++ +R+RDR++ER+RQ E++R QRE R+RE DRE
Sbjct: 104 RKRETDRNRERNRKGGRERD-KQTERERDRERERQRQRERERQRQRE----RKRETDRER 158
Query: 427 ERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
+R ER ER+K++ +ER +ER+ ++ ++R+
Sbjct: 159 QRWAER-EERKKERKKERKKERKEKKKEEKRRE 190
Score = 179 bits (454), Expect = 6e-45
Identities = 91/184 (49%), Positives = 139/184 (75%), Gaps = 5/184 (2%)
Query: 280 ERQTDRKRQRRTERDRETERKRERQRERERERER-NRKRERERERERERERQRETERDRE 338
ERQ +RKR+ T+R +ETER+R+RQRERE + ER NR R+R+R RER+R+ RE ER+R+
Sbjct: 2 ERQRERKRE--TDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
Query: 339 KERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE-ERERDRDRDRQ 397
KER+R+R+R+ E +RE RQ R+ +R+ +R+ +RER++DR R+RE +R R+R+R
Sbjct: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 398 KERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGR-ERDRERQTDRQAGR 456
+ER++QTE++RD +RE ++QRERE+ R+ ER RE RER++ R ER +ER+ +R+ R
Sbjct: 120 RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKER 179
Query: 457 QRKR 460
+ K+
Sbjct: 180 KEKK 183
Score = 178 bits (452), Expect = 1e-44
Identities = 82/185 (44%), Positives = 136/185 (73%), Gaps = 7/185 (3%)
Query: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
+RER+RQ+ERE + E+ R+ DR RER R+ DR ++R+R +ER DR+++RER+T+RE
Sbjct: 18 ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER--DRQRQRERETERE 75
Query: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
+RQRE++R R+++R+ + ER+ +R R+R+ + R RER R +ER++QT+RER R+ E
Sbjct: 76 TERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERE 135
Query: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
R RQ+ERER++ R+ +RE +R+R++ + E+R ER +ER++ER+ E+K++ R
Sbjct: 136 RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK-----EKKKEEKRRE 190
Query: 233 DRQRK 237
D++RK
Sbjct: 191 DKKRK 195
Score = 155 bits (393), Expect = 8e-38
Identities = 87/195 (44%), Positives = 121/195 (62%), Gaps = 8/195 (4%)
Query: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER 369
ER+R RKRE +R +E ERER R+ ER+ + ERE R RQ + RER+RQT R E+
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERE-NRHRQRDRHRERDRQTDR------EK 54
Query: 370 ERERERERDRQSARERE-ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESER 428
ERER++ERDRQ RERE ERE +R R+RQ++RER+ + DR+ ++ +++R+RE DR ER
Sbjct: 55 ERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114
Query: 429 GRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGI 488
R+ GRER+KQ RERDRER+ RQ R+R+R R + + + + +
Sbjct: 115 NRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKE 174
Query: 489 RWKSSPEDPKAASTR 503
R K E K R
Sbjct: 175 RKKERKEKKKEEKRR 189
Score = 154 bits (388), Expect = 3e-37
Identities = 81/189 (42%), Positives = 128/189 (67%), Gaps = 17/189 (8%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDADGD---DRERNRQKERERRREK-RQTERETDRKRE 80
D R R E R H++ D ++ER RQKER+R+R++ R+TERET+R+RE
Sbjct: 22 DRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRE 81
Query: 81 RRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD 140
R+R+++R R+ DR ER +DR++ER+R+TDR R+R R+ R R K+ ERE +RE ER
Sbjct: 82 RQRQRERKRQTDR--ERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERER--- 136
Query: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
QR+RER+R ++ER+R+TDRERQR ER +ER++E+ ++ ++ER+ ++++E +
Sbjct: 137 -----QRQRERERQRQRERKRETDRERQRWAER---EERKKERKKERKKERKEKKKEEKR 188
Query: 201 TEDRHSERG 209
ED+ + G
Sbjct: 189 REDKKRKWG 197
Score = 153 bits (387), Expect = 4e-37
Identities = 80/185 (43%), Positives = 125/185 (67%), Gaps = 9/185 (4%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
R R +E + H+ D RER+RQ +RE+ RE RQ ER+ R+RER E++
Sbjct: 19 RERDRQRERENQTERENRHRQRDRH-RERDRQTDREKERE-RQKERDRQRQRERETERET 76
Query: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
R+R+R R+R+R R+ +RER DR+R+R+RE +RN RE R+G R RD+QT+ +R
Sbjct: 77 ERQRERQRQRERKRQTDRERDKDRDRERKRETDRN------RERNRKGGRERDKQTERER 130
Query: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQER-RERERQREKENKTEDRHS 206
+RER+R ++ERERQ RER+R+T+R RQ+ ERE+ ++ER +ER+++R+++ K E R
Sbjct: 131 DRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRRE 190
Query: 207 ERGRE 211
++ R+
Sbjct: 191 DKKRK 195
Score = 122 bits (307), Expect = 7e-28
Identities = 63/154 (40%), Positives = 104/154 (67%), Gaps = 6/154 (3%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
D + R +E R+R + + RER RQ+ER+R+ ++ ER+ DR RER+RE
Sbjct: 51 DREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDR---ERDKDRDRERKRE 107
Query: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
DR+R+R+R R+RD++ ERER +RER RQRE+ER RQ+ER+RET+RE +R +R+
Sbjct: 108 TDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE-- 165
Query: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
+R++ER+++ +KER+ + E++R+ ++ + E
Sbjct: 166 -ERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
Score = 114 bits (285), Expect = 3e-25
Identities = 76/206 (36%), Positives = 107/206 (51%), Gaps = 20/206 (9%)
Query: 350 EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDR------DRQKERERQ 403
E RER R+T R ++ ERER+R+RER+ Q+ RE R+RDR R DR+KERERQ
Sbjct: 2 ERQRERKRETDRG--KETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
Query: 404 TEKDRDGQRETEKQREREKDRESERGRERGR--EREKQKGRERDRERQTDRQAGRQRKRS 461
E+DR QRE E +RE E+ RE +R RER R +RE+ K R+R+R+R+TDR R RK
Sbjct: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 462 TLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGR- 520
+T R + + R R + + R W + + R R
Sbjct: 120 R---ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERK 176
Query: 521 ------RRWEPRLGEKRGQGGEGRRP 540
++ E R +K+ + GEG P
Sbjct: 177 KERKEKKKEEKRREDKKRKWGEGISP 202
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 184 bits (467), Expect = 2e-46
Identities = 92/200 (46%), Positives = 146/200 (73%), Gaps = 16/200 (8%)
Query: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE 215
E+ER+R+ +R+R+R ER+R+K+RE EK+R +R+R+R+R++ R +R RER +
Sbjct: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRW-----RDRDRKRERWGD 113
Query: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
R+ ETETER+ + +R+RDR+R+ +RER++Q RE DK+RE E ++DRDR+R
Sbjct: 114 RDRETETERQEERERQRDRKREKDRERQRQ--------REIGIDKDREIETEKDRDRERE 165
Query: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER 335
E ER DR+R+R+ +R+ +R RERQRE+E +R R R+R++ERE++R R+RET R
Sbjct: 166 MGETERYRDRERERQKQRETRRDRDRERQREKE---DRERDRDRQKEREKDRYRERETGR 222
Query: 336 DREKERERKRKRQTEMDRER 355
DR+KER+R+R+R+ + DR++
Sbjct: 223 DRDKERDRERQREKDRDRQK 242
Score = 184 bits (466), Expect = 3e-46
Identities = 90/191 (47%), Positives = 140/191 (73%), Gaps = 8/191 (4%)
Query: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
R+R+R Q+ERERQ R ++R E+DRE E+ R+RQR+R+RER+R R R+R+RER +R+R
Sbjct: 58 RERER-QRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
Query: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERE 389
+ ETER E+ER+R RKR+ + +R+R R+ G +++RE E E+DR RE E E
Sbjct: 117 ETETERQEERERQRDRKREKDRERQRQREIG------IDKDREIETEKDRDREREMGETE 170
Query: 390 RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQ 449
R RDR+R+++++R+T +DRD +R+ EK+ +RE+DR+ ++ RE+ R RE++ GR+RD+ER
Sbjct: 171 RYRDRERERQKQRETRRDRDRERQREKE-DRERDRDRQKEREKDRYRERETGRDRDKERD 229
Query: 450 TDRQAGRQRKR 460
+RQ + R R
Sbjct: 230 RERQREKDRDR 240
Score = 180 bits (456), Expect = 4e-45
Identities = 97/203 (47%), Positives = 146/203 (71%), Gaps = 20/203 (9%)
Query: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR 295
R+ ER+RE++ +R+RA ER E+D+E E++RDR R RDR +++R R DRKR+R +RDR
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDR-ERQRWRDRDRKRERWGDRDR 116
Query: 296 ETERKRERQRERERERERNRKRERERERER--ERERQRETERDREKERERKRKRQTEMDR 353
ETE +R+ +RER+R+R+R + RER+R+RE +++R+ ETE+DR++ERE + DR
Sbjct: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR-DR 175
Query: 354 ERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRE 413
ER RQ RE RR +R+RER+RE++ +R+RDRDRQKER EKDR +RE
Sbjct: 176 ERERQKQRETRR--DRDRERQREKE----------DRERDRDRQKER----EKDRYRERE 219
Query: 414 TEKQREREKDRESERGRERGRER 436
T + R++E+DRE +R ++R R++
Sbjct: 220 TGRDRDKERDRERQREKDRDRQK 242
Score = 179 bits (455), Expect = 5e-45
Identities = 98/202 (48%), Positives = 140/202 (69%), Gaps = 24/202 (11%)
Query: 189 RERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAER 248
RERERQRE+E R +R +ER RE++ E E +R RQ R+R+RQR +R+R+++
Sbjct: 58 RERERQRERE-----RQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWG 112
Query: 249 ERASERETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERDR-------ETERK 300
+R E ETER +ERER+RDR R++DR RQ++RE D+ R+ TE+DR ETER
Sbjct: 113 DRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY 172
Query: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
R+R+RER+++RE R R+RER+RE+E RE +RDR+KERE+ DR R R+TG
Sbjct: 173 RDRERERQKQRETRRDRDRERQREKE---DRERDRDRQKEREK--------DRYRERETG 221
Query: 361 REGRRQAERERERERERDRQSA 382
R+ ++ +RER+RE++RDRQ A
Sbjct: 222 RDRDKERDRERQREKDRDRQKA 243
Score = 179 bits (453), Expect = 8e-45
Identities = 83/185 (44%), Positives = 136/185 (73%), Gaps = 3/185 (1%)
Query: 91 RDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERE 150
R+R R+R+R+R+++R ++ RE+DR+ EK+R+RQ++R+RE +R +R R R+ G R+RE
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
Query: 151 RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGR 210
+ + ++ERERQ DR+R++ ER RQ+E +K+R+ E++R RE+E +R+ +R R
Sbjct: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
Query: 211 ERERERETETETERKRQ---TDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
ER+++RET + +R+RQ DRERDR R+ ERE+++ ERE +R+ ERD+ER+RE+D
Sbjct: 178 ERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKD 237
Query: 268 RDRDR 272
RDR +
Sbjct: 238 RDRQK 242
Score = 177 bits (449), Expect = 2e-44
Identities = 91/191 (47%), Positives = 141/191 (73%), Gaps = 8/191 (4%)
Query: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR-RQKERER 281
ER+RQ +RER R+R ER REK E E+ +R+ +RD+ER+R RDRDR R+R ++RE
Sbjct: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
Query: 282 QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
+T+R+ +R +RDR+ E+ RERQR+RE +++R+ E E++R+RERE ETER R++ER
Sbjct: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE-MGETERYRDRER 177
Query: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE---ERERDRDRDRQK 398
ER+++R+T DR+R RQ +E R ER+R+R++ER++ RERE +R+++RDR+RQ+
Sbjct: 178 ERQKQRETRRDRDRERQREKEDR---ERDRDRQKEREKDRYRERETGRDRDKERDRERQR 234
Query: 399 ERERQTEKDRD 409
E++R +K D
Sbjct: 235 EKDRDRQKAID 245
Score = 176 bits (445), Expect = 7e-44
Identities = 102/217 (47%), Positives = 147/217 (67%), Gaps = 24/217 (11%)
Query: 240 REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETER 299
RERE+Q ERER + +R KER RE+DR+ ++DR +R+R+ DR+RQR +RDR+ ER
Sbjct: 58 RERERQRERER----QRKRAKERHREKDREIEKDR---DRQRKRDRERQRWRDRDRKRER 110
Query: 300 KRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQT 359
+R RE E ER+ R+R+R+R+RE++RERQR+ E +K+RE +TE DR+R R+
Sbjct: 111 WGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREI----ETEKDRDREREM 166
Query: 360 GREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRE 419
G R R+RERER++ R E RDRDR+RQ+E+E E+DRD Q+E EK R
Sbjct: 167 GETERY---RDRERERQKQR-------ETRRDRDRERQREKE-DRERDRDRQKEREKDRY 215
Query: 420 REKDRESERGRERGREREKQKGRERDRERQTDRQAGR 456
RE RE+ R R++ R+RE+Q+ ++RDR++ D GR
Sbjct: 216 RE--RETGRDRDKERDRERQREKDRDRQKAIDCVPGR 250
Score = 175 bits (444), Expect = 9e-44
Identities = 90/200 (45%), Positives = 141/200 (70%), Gaps = 16/200 (8%)
Query: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113
RER RQ+ERER+R KR ER ++ RE +++DR RKRDR R+R RDR+++RER DR+R
Sbjct: 58 RERERQRERERQR-KRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
Query: 114 DRQ--REKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
+ + R++ER RQ++R+RE +RE +R R+ D RE E ++D ++ERE +T
Sbjct: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE-------MGET 169
Query: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
ER R +ERER+K R+ RR+R+R+R++E + +R R+R+R++E E + R+R+T R+
Sbjct: 170 ERYRDRERERQKQRETRRDRDRERQREKE------DRERDRDRQKEREKDRYRERETGRD 223
Query: 232 RDRQRKTEREREKQAERERA 251
RD++R ER+REK +R++A
Sbjct: 224 RDKERDRERQREKDRDRQKA 243
Score = 172 bits (435), Expect = 1e-42
Identities = 85/195 (43%), Positives = 139/195 (71%), Gaps = 14/195 (7%)
Query: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
R+ + QRERERQR KER R+ DRE ++ +R R+++RER++ R R+RER +++ +
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
Query: 201 TE-DRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ---AERERASERET 256
TE +R ER R+R+R+RE + E +R+R+ ++DR+ +TE++R+++ E ER +RE
Sbjct: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177
Query: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK 316
ER K+RE RDRDR+R R +++RER +RDR+ ER+++R RERE R+R+++
Sbjct: 178 ERQKQRETRRDRDRERQREKEDRER----------DRDRQKEREKDRYRERETGRDRDKE 227
Query: 317 RERERERERERERQR 331
R+RER+RE++R+RQ+
Sbjct: 228 RDRERQREKDRDRQK 242
Score = 154 bits (390), Expect = 2e-37
Identities = 79/165 (47%), Positives = 119/165 (72%), Gaps = 9/165 (5%)
Query: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR 364
RERER+RER R+R+R +ER RE++R+ E +RDR+++R+R+R+R + DR+R R R+
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
Query: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRET-------EKQ 417
+ ER+ ERER+RDR+ ++RE R+R R+ K+RE +TEKDRD +RE +++
Sbjct: 118 TETERQEERERQRDRKREKDRE-RQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
Query: 418 REREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRST 462
RER+K RE+ R R+R R+REK+ RERDR+RQ +R+ R R+R T
Sbjct: 177 RERQKQRETRRDRDRERQREKED-RERDRDRQKEREKDRYRERET 220
Score = 145 bits (365), Expect = 1e-34
Identities = 82/210 (39%), Positives = 136/210 (64%), Gaps = 28/210 (13%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
R R +E R+R + H++ D RE + ++R+R+R+ RER+R +DR
Sbjct: 60 RERQRERERQRKRAK-ERHREKD---REIEKDRDRQRKRD-----------RERQRWRDR 104
Query: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
RKR+R +R R+ E ER+ + +R+RDR+REK+R RQ++RE +++ R+ +T+ R
Sbjct: 105 DRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKD----REIETEKDR 160
Query: 148 ERERQR-DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206
+RER+ + E+ R+R+ +R++QR+T R+R +ER+REK E RER+R R+KE R
Sbjct: 161 DREREMGETERYRDRERERQKQRETRRDRDRERQREK---EDRERDRDRQKE-----REK 212
Query: 207 ERGRERERERETETETERKRQTDRERDRQR 236
+R RERE R+ + E +R+RQ +++RDRQ+
Sbjct: 213 DRYRERETGRDRDKERDRERQREKDRDRQK 242
Score = 119 bits (299), Expect = 6e-27
Identities = 71/173 (41%), Positives = 104/173 (60%), Gaps = 15/173 (8%)
Query: 22 IPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRER 81
I D R+R +E R R + + DRE +++ ER +R+R+R
Sbjct: 84 IEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEER-----------ERQRDR 132
Query: 82 RREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDR 141
+REKDR R+R R +DRE E E+ DRER+ E ER R +ERER+ +RE R RDR
Sbjct: 133 KREKDRERQRQREIGIDKDREIETEKDRDRERE-MGETERYRDRERERQKQRETRRDRDR 191
Query: 142 QTDGQRE-RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
+ ++E RER RD +KERE+ DR R+R+T R+R KER+RE+ R++ R+R++
Sbjct: 192 ERQREKEDRERDRDRQKEREK--DRYRERETGRDRDKERDRERQREKDRDRQK 242
Score = 111 bits (278), Expect = 2e-24
Identities = 66/164 (40%), Positives = 102/164 (62%), Gaps = 25/164 (15%)
Query: 24 LDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK-RQTERETDRKRERR 82
++ R R ++ R+R + K DR+R + ER+ RE+ R +RE DR+R+R+
Sbjct: 84 IEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQ 143
Query: 83 RE------------KDRHRKRD-----RHRERQRDREKERERQTDRERDRQREKE----- 120
RE KDR R+R+ R+R+R+R+R+K+RE + DR+R+RQREKE
Sbjct: 144 REIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERD 203
Query: 121 RNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTD 164
R+RQKERE++ RE E GRDR D +R+RERQR+ +++R++ D
Sbjct: 204 RDRQKEREKDRYRERETGRDR--DKERDRERQREKDRDRQKAID 245
Score = 88.2 bits (217), Expect = 2e-17
Identities = 52/125 (41%), Positives = 78/125 (62%), Gaps = 19/125 (15%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRER------ 81
R+R +E R+R +G DRE +K+R+R RE +TER DR+RER
Sbjct: 132 RKREKDRERQRQREIGI------DKDREIETEKDRDREREMGETERYRDRERERQKQRET 185
Query: 82 RREKDRHRKRDRH-RERQRDREKERE------RQTDRERDRQREKERNRQKERERETERE 134
RR++DR R+R++ RER RDR+KERE R+T R+RD++R++ER R+K+R+R+ +
Sbjct: 186 RRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAID 245
Query: 135 GERGR 139
GR
Sbjct: 246 CVPGR 250
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 175 bits (443), Expect = 1e-43
Identities = 94/312 (30%), Positives = 181/312 (58%), Gaps = 23/312 (7%)
Query: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
S+ R S+ RR+ H+ +R R+RQK+R R + ++ + RERR+ +
Sbjct: 314 SKSRSSSKSHSRRKRSQSKHRSRS-HNRSRSRQKDRRR---SKSPHKKRSKSRERRKSRS 369
Query: 87 RHRKRDRHRE-RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG 145
R RD+ ++ R++ +EKER ++ DRE++R+REKER ++KER + +R+ ER +D
Sbjct: 370 RSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD----- 424
Query: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH 205
RE+++++D E+ERE++ +++R ++ E+ + KE+EREK+R + + +R+++K+++T R
Sbjct: 425 -REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 483
Query: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE 265
R R + ER+R+ R R +T + ++++ R + ++DK+RE+E
Sbjct: 484 YNASR-----RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 538
Query: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERER 325
RD +R +ERER T R++ DR+ + K E+ +E+E N++ + +E
Sbjct: 539 RDHISER----RERERSTS---MRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEV 591
Query: 326 ERERQRETERDR 337
+ + TE ++
Sbjct: 592 DDKDAPRTEENK 603
Score = 174 bits (442), Expect = 2e-43
Identities = 97/311 (31%), Positives = 175/311 (56%), Gaps = 22/311 (7%)
Query: 103 KERERQTDRERDRQREKERNRQKE---RERETEREGERGRDRQTDGQRERERQRDAEKER 159
K ER+ R R R K R+ K R+R + R +R Q++R R + K+R
Sbjct: 299 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 358
Query: 160 ERQTDRERQRQTERNRQKERE-REKNRQERRERERQREKENKTEDRHSERGRERERERET 218
+ +R + R +R K ++ REK +++ R +E+ REKE R E+ RE+E+ER
Sbjct: 359 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE-----REREKEREKEKERGK 413
Query: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD-RRQK 277
+ +++R+ DRE+D+++ EREREK+ E++R E+E E+DKE+ERE+DR ++ D +R+K
Sbjct: 414 NKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 473
Query: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERER--------ERER 329
+++ +T + + R R + R+R R+R R R + +R+ R ++++
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533
Query: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQ---AERERERERERDRQSARERE 386
+RE ERD ER R+R+R T M + N + G+E + + +E+E +E D ++E +
Sbjct: 534 KREKERDHISER-RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVD 592
Query: 387 ERERDRDRDRQ 397
+++ R + +
Sbjct: 593 DKDAPRTEENK 603
Score = 172 bits (437), Expect = 6e-43
Identities = 105/370 (28%), Positives = 187/370 (50%), Gaps = 34/370 (9%)
Query: 103 KERERQTDRERDRQR------EKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156
KE E R R+ Q E E + ER+ R R + R + R R+R
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQS 331
Query: 157 KERERQTDRERQRQTERNRQKE--REREKNRQERRERERQREKENKTEDRHSERGRERER 214
K R R +R R RQ +R R K ++R K+R+ R+ R R ++ + + R E+ +E+ER
Sbjct: 332 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR--EKIKEKER 389
Query: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR 274
+E + E ER+R+ +RE++++R ++R+K+ E++R E++ E+D+ERERE++ ++DRD
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDR--EKDKEKDREREREKEHEKDRD- 446
Query: 275 RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETE 334
KE+E+ E+D+E ER+++R +E + +R++++K R R +
Sbjct: 447 --KEKEK----------EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 494
Query: 335 RDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDR 394
R+R + R R R + R++ R ++ +++++RE++R ER ERER
Sbjct: 495 RERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 554
Query: 395 DRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE-KQKGRERDRERQTDRQ 453
R++ DRDG+ + EK K++E + + +E K R E +
Sbjct: 555 -------RKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHN 607
Query: 454 AGRQRKRSTL 463
Q L
Sbjct: 608 GNCQLNEENL 617
Score = 169 bits (427), Expect = 9e-42
Identities = 91/316 (28%), Positives = 172/316 (54%), Gaps = 17/316 (5%)
Query: 42 LGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDR 101
+ A + G ER + R R K ++ ++ +R+R + K R R +R R RQ+DR
Sbjct: 289 ISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR 348
Query: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER 161
+ + R + R+R K R+R R++ + R+ ++ER +++D EKERER
Sbjct: 349 RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-------REKIKEKERVKEKDREKERER 401
Query: 162 QTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETE 221
+ +RE++++ +N+ +++EREK+R++ +E++R+RE+E + E+ R++E+E+E + E
Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE-----KEHEKDRDKEKEKEQDKE 456
Query: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD-RRQKERE 280
ER++ +E D +RK +++ AS R +ER R R R R R K +
Sbjct: 457 KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 516
Query: 281 RQTDRKRQRRTERDRETERKRERQRERE-RERERN---RKRERERERERERERQRETERD 336
R++ R R+ ++ +R++ER E RERER+ RK +R+ + + E+ + ++
Sbjct: 517 RKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE 576
Query: 337 REKERERKRKRQTEMD 352
+E +E E+D
Sbjct: 577 KEHNKEPDSSVSKEVD 592
Score = 166 bits (419), Expect = 7e-41
Identities = 92/306 (30%), Positives = 173/306 (56%), Gaps = 11/306 (3%)
Query: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQER--RERERQREKENKTEDRHSERGRER 212
A KE E R R+ Q+ + E E K+ + + R R R K + HS R R +
Sbjct: 271 AAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQ 330
Query: 213 ERERETETETERKRQTDRERDRQ--RKTEREREKQAERERASERETERD-KERERERDRD 269
+ R R RQ DR R + +K + RE++ R R+ R+ +D +E+ +E++R
Sbjct: 331 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV 390
Query: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
+++DR E+ER+ +++R++ ER + +R +ER+++RE+++E++R+RERE+E E++R++
Sbjct: 391 KEKDR---EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 447
Query: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERE 389
++E E+D+EKERE+ R ++ + R++++++ R R R R+R+ R R
Sbjct: 448 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 507
Query: 390 RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQK-GRERDRER 448
R K + ++ R + + +K+RE+E+D SER RER R +K +RD +
Sbjct: 508 SPRTSKTIKRKSSRSPSPR-SRNKKDKKREKERDHISER-RERERSTSMRKSSNDRDGKE 565
Query: 449 QTDRQA 454
+ ++ +
Sbjct: 566 KLEKNS 571
Score = 144 bits (363), Expect = 2e-34
Identities = 79/261 (30%), Positives = 142/261 (54%), Gaps = 27/261 (10%)
Query: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
++ + +R RE Q+ A E E+ + ER+ R R R + + + + RKR +
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 332
Query: 292 ERDRETERKRERQRERERERERNRKRERERERERERER-----QRETERDREKERERKRK 346
R R R R RQ++R R + ++KR + RER + R R +R+ R++ KE+ER ++
Sbjct: 333 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 392
Query: 347 RQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK 406
+ E +RER ++ +E R ++R++ERE+DR+ +E++ RER+R+++ +K+R+++ EK
Sbjct: 393 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD-REREREKEHEKDRDKEKEK 451
Query: 407 DRDGQRETEKQREREKDRE----------------SERGRERGREREKQKGRERDRERQT 450
++D ++E EK R +E D + S R R RER +++ R R +T
Sbjct: 452 EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRT 511
Query: 451 DRQAGRQRKRSTLYVNPPPRT 471
+ R+ RS P PR+
Sbjct: 512 SKTIKRKSSRS-----PSPRS 527
Score = 71.6 bits (174), Expect = 2e-12
Identities = 57/219 (26%), Positives = 106/219 (48%), Gaps = 34/219 (15%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
D + R +E + + + + DR++ ++KE+++ +E R+++R +E
Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKE---------REKDRSKE 466
Query: 85 KDRHRKRDRHRERQRDRE---KERERQTDRERDRQREKERNRQKERERETEREGERG--- 138
D RK+D+ + R R R R + RER R+R + +R + +R+ R
Sbjct: 467 IDEKRKKDK-KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP 525
Query: 139 RDR-QTDGQRERERQRDAE-KERERQT-------DRERQRQTERNRQKEREREKNRQ--- 186
R R + D +RE+ER +E +ERER T DR+ + + E+N +E+E N++
Sbjct: 526 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 585
Query: 187 ----ERRERERQREKENKTEDRHSERGRERERERETETE 221
E +++ R +ENK + H+ + E T+TE
Sbjct: 586 SVSKEVDDKDAPRTEENKIQ--HNGNCQLNEENLSTKTE 622
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 175 bits (443), Expect = 1e-43
Identities = 94/312 (30%), Positives = 181/312 (58%), Gaps = 23/312 (7%)
Query: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
S+ R S+ RR+ H+ +R R+RQK+R R + ++ + RERR+ +
Sbjct: 198 SKSRSSSKSHSRRKRSQSKHRSRS-HNRSRSRQKDRRR---SKSPHKKRSKSRERRKSRS 253
Query: 87 RHRKRDRHRE-RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG 145
R RD+ ++ R++ +EKER ++ DRE++R+REKER ++KER + +R+ ER +D
Sbjct: 254 RSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD----- 308
Query: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH 205
RE+++++D E+ERE++ +++R ++ E+ + KE+EREK+R + + +R+++K+++T R
Sbjct: 309 -REKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 367
Query: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE 265
R R + ER+R+ R R +T + ++++ R + ++DK+RE+E
Sbjct: 368 YNASR-----RSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 422
Query: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERER 325
RD +R +ERER T R++ DR+ + K E+ +E+E N++ + +E
Sbjct: 423 RDHISER----RERERSTS---MRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEV 475
Query: 326 ERERQRETERDR 337
+ + TE ++
Sbjct: 476 DDKDAPRTEENK 487
Score = 174 bits (442), Expect = 2e-43
Identities = 97/311 (31%), Positives = 175/311 (56%), Gaps = 22/311 (7%)
Query: 103 KERERQTDRERDRQREKERNRQKE---RERETEREGERGRDRQTDGQRERERQRDAEKER 159
K ER+ R R R K R+ K R+R + R +R Q++R R + K+R
Sbjct: 183 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 242
Query: 160 ERQTDRERQRQTERNRQKERE-REKNRQERRERERQREKENKTEDRHSERGRERERERET 218
+ +R + R +R K ++ REK +++ R +E+ REKE R E+ RE+E+ER
Sbjct: 243 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKE-----REREKEREKEKERGK 297
Query: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD-RRQK 277
+ +++R+ DRE+D+++ EREREK+ E++R E+E E+DKE+ERE+DR ++ D +R+K
Sbjct: 298 NKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 357
Query: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERER--------ERER 329
+++ +T + + R R + R+R R+R R R + +R+ R ++++
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417
Query: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQ---AERERERERERDRQSARERE 386
+RE ERD ER R+R+R T M + N + G+E + + +E+E +E D ++E +
Sbjct: 418 KREKERDHISER-RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVD 476
Query: 387 ERERDRDRDRQ 397
+++ R + +
Sbjct: 477 DKDAPRTEENK 487
Score = 172 bits (437), Expect = 6e-43
Identities = 105/370 (28%), Positives = 187/370 (50%), Gaps = 34/370 (9%)
Query: 103 KERERQTDRERDRQR------EKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156
KE E R R+ Q E E + ER+ R R + R + R R+R
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR-RKRSQS 215
Query: 157 KERERQTDRERQRQTERNRQKE--REREKNRQERRERERQREKENKTEDRHSERGRERER 214
K R R +R R RQ +R R K ++R K+R+ R+ R R ++ + + R E+ +E+ER
Sbjct: 216 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR--EKIKEKER 273
Query: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR 274
+E + E ER+R+ +RE++++R ++R+K+ E++R E++ E+D+ERERE++ ++DRD
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDR--EKDKEKDREREREKEHEKDRD- 330
Query: 275 RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETE 334
KE+E+ E+D+E ER+++R +E + +R++++K R R +
Sbjct: 331 --KEKEK----------EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS 378
Query: 335 RDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDR 394
R+R + R R R + R++ R ++ +++++RE++R ER ERER
Sbjct: 379 RERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSM 438
Query: 395 DRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE-KQKGRERDRERQTDRQ 453
R++ DRDG+ + EK K++E + + +E K R E +
Sbjct: 439 -------RKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHN 491
Query: 454 AGRQRKRSTL 463
Q L
Sbjct: 492 GNCQLNEENL 501
Score = 169 bits (427), Expect = 9e-42
Identities = 91/316 (28%), Positives = 172/316 (54%), Gaps = 17/316 (5%)
Query: 42 LGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDR 101
+ A + G ER + R R K ++ ++ +R+R + K R R +R R RQ+DR
Sbjct: 173 ISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR 232
Query: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER 161
+ + R + R+R K R+R R++ + R+ ++ER +++D EKERER
Sbjct: 233 RRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT-------REKIKEKERVKEKDREKERER 285
Query: 162 QTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETE 221
+ +RE++++ +N+ +++EREK+R++ +E++R+RE+E + E+ R++E+E+E + E
Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE-----KEHEKDRDKEKEKEQDKE 340
Query: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD-RRQKERE 280
ER++ +E D +RK +++ AS R +ER R R R R R K +
Sbjct: 341 KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 400
Query: 281 RQTDRKRQRRTERDRETERKRERQRERE-RERERN---RKRERERERERERERQRETERD 336
R++ R R+ ++ +R++ER E RERER+ RK +R+ + + E+ + ++
Sbjct: 401 RKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE 460
Query: 337 REKERERKRKRQTEMD 352
+E +E E+D
Sbjct: 461 KEHNKEPDSSVSKEVD 476
Score = 166 bits (419), Expect = 7e-41
Identities = 92/306 (30%), Positives = 173/306 (56%), Gaps = 11/306 (3%)
Query: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQER--RERERQREKENKTEDRHSERGRER 212
A KE E R R+ Q+ + E E K+ + + R R R K + HS R R +
Sbjct: 155 AAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQ 214
Query: 213 ERERETETETERKRQTDRERDRQ--RKTEREREKQAERERASERETERD-KERERERDRD 269
+ R R RQ DR R + +K + RE++ R R+ R+ +D +E+ +E++R
Sbjct: 215 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV 274
Query: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
+++DR E+ER+ +++R++ ER + +R +ER+++RE+++E++R+RERE+E E++R++
Sbjct: 275 KEKDR---EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 331
Query: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERE 389
++E E+D+EKERE+ R ++ + R++++++ R R R R+R+ R R
Sbjct: 332 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 391
Query: 390 RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQK-GRERDRER 448
R K + ++ R + + +K+RE+E+D SER RER R +K +RD +
Sbjct: 392 SPRTSKTIKRKSSRSPSPR-SRNKKDKKREKERDHISER-RERERSTSMRKSSNDRDGKE 449
Query: 449 QTDRQA 454
+ ++ +
Sbjct: 450 KLEKNS 455
Score = 144 bits (363), Expect = 2e-34
Identities = 79/261 (30%), Positives = 142/261 (54%), Gaps = 27/261 (10%)
Query: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
++ + +R RE Q+ A E E+ + ER+ R R R + + + + RKR +
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 216
Query: 292 ERDRETERKRERQRERERERERNRKRERERERERERER-----QRETERDREKERERKRK 346
R R R R RQ++R R + ++KR + RER + R R +R+ R++ KE+ER ++
Sbjct: 217 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 276
Query: 347 RQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK 406
+ E +RER ++ +E R ++R++ERE+DR+ +E++ RER+R+++ +K+R+++ EK
Sbjct: 277 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD-REREREKEHEKDRDKEKEK 335
Query: 407 DRDGQRETEKQREREKDRE----------------SERGRERGREREKQKGRERDRERQT 450
++D ++E EK R +E D + S R R RER +++ R R +T
Sbjct: 336 EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRT 395
Query: 451 DRQAGRQRKRSTLYVNPPPRT 471
+ R+ RS P PR+
Sbjct: 396 SKTIKRKSSRS-----PSPRS 411
Score = 71.6 bits (174), Expect = 2e-12
Identities = 57/219 (26%), Positives = 106/219 (48%), Gaps = 34/219 (15%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
D + R +E + + + + DR++ ++KE+++ +E R+++R +E
Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKE---------REKDRSKE 350
Query: 85 KDRHRKRDRHRERQRDRE---KERERQTDRERDRQREKERNRQKERERETEREGERG--- 138
D RK+D+ + R R R R + RER R+R + +R + +R+ R
Sbjct: 351 IDEKRKKDK-KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP 409
Query: 139 RDR-QTDGQRERERQRDAE-KERERQT-------DRERQRQTERNRQKEREREKNRQ--- 186
R R + D +RE+ER +E +ERER T DR+ + + E+N +E+E N++
Sbjct: 410 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 469
Query: 187 ----ERRERERQREKENKTEDRHSERGRERERERETETE 221
E +++ R +ENK + H+ + E T+TE
Sbjct: 470 SVSKEVDDKDAPRTEENKIQ--HNGNCQLNEENLSTKTE 506
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 171 bits (433), Expect = 2e-42
Identities = 122/482 (25%), Positives = 252/482 (52%), Gaps = 54/482 (11%)
Query: 31 PGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRK 90
P Q + + + + ++ +++ +Q+E+ R+E+R E+E + RE+ + R K
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE-GKMREQEEKMWRQEK 321
Query: 91 RDRHRERQ-RDREKE-RERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148
R R +E++ R++EKE RE++ RE++ Q +++ + E+E E RE E RQ + E
Sbjct: 322 RLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE-EKMREQEEKMWRQEERLWE 380
Query: 149 RERQRDAEKERERQTDRERQRQTERNRQKE---REREK---NRQERRERERQREKENKTE 202
+E+Q ++++ R + Q ER R+KE RE+EK ++ RE ++ +E+E KT
Sbjct: 381 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR 440
Query: 203 DRHS-----ERGRERERERETETETERKRQTDRERDRQRKTERE------------REKQ 245
D+ ER RERE++ E ET R+++ ++ + E+E +EK
Sbjct: 441 DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 500
Query: 246 AERERASERETERDKERERERDRDR----------------------DRDRRQKERER-- 281
E+E+ E+E + ++ E+ RD++ +++ + +++E+
Sbjct: 501 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 560
Query: 282 --QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
Q +R ++ E++++T + E+ RE ER RER +K E E RE+E + + + ++ +
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERERER-ERERDRQSAREREERERDRDRDRQK 398
E+E K Q E +E+ + + + E+E + E++R + + E E+ +++++ +
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQ 680
Query: 399 ERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQR 458
E+E + + +++T++Q ++ D+E R E REREK+ E + R+ + + Q
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740
Query: 459 KR 460
++
Sbjct: 741 EK 742
Score = 164 bits (414), Expect = 3e-40
Identities = 105/439 (23%), Positives = 231/439 (52%), Gaps = 26/439 (5%)
Query: 44 QAHKDADGDDR-----ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQ 98
Q K D ++R ER R+KE R +++ E+ + E++ ++ + RD+ + Q
Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Query: 99 RD-REKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRER--ERQRDA 155
+ R +ERE++ E + RE+E QK+ E E+E + + ++ Q+E+ E+++
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Query: 156 EKERERQTDRERQRQTER---------NRQKEREREKNRQERRERERQREKENKTEDRHS 206
E+E + E+ R E ++K RE+E E+ E+ R +E++ ++
Sbjct: 508 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 567
Query: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
E+ + +E+E++T + E+ R+ +R R+R++K E E E+E + + E+ +E+E +
Sbjct: 568 EK-KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626
Query: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETER---KRERQRERERERERNRKRERERER 323
++ + Q+E+ + + K + E+ E +R ++E+ E E+ +E+ + +E+E +
Sbjct: 627 WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKI 686
Query: 324 ERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAR 383
+ + +++T+ +K ++++ R+ E RER ++ E E+E + + + ++ +
Sbjct: 687 WEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746
Query: 384 EREERERDRDRDRQKER---ERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQK 440
E E E++ Q+E+ +++ + ++ E EK +E+EK E E + R +E EK +
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEE-KMRDQE-EKMR 804
Query: 441 GRERDRERQTDRQAGRQRK 459
G+E Q ++ G++ K
Sbjct: 805 GQEEKMRGQEEKMRGQEEK 823
Score = 155 bits (392), Expect = 1e-37
Identities = 113/472 (23%), Positives = 245/472 (51%), Gaps = 52/472 (11%)
Query: 35 ESPRRRGLGQAHKDADGDDRERNRQKERERRREKR-QTERETDRKRERRREKDRHRKRDR 93
E R Q + D E+ +++ER R REK+ + E ET R++E + +K ++
Sbjct: 424 EKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 483
Query: 94 HRE--RQRDREKERERQTDRERDRQREKERNRQKERERETER---------EGERGRDRQ 142
+ +Q+ +++E+ ++E+ +++E++ Q+E+ R+ E E+ R+++
Sbjct: 484 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543
Query: 143 TDGQRERERQRDAEK------ERERQTDRERQRQT----ERNRQKEREREKNRQERRERE 192
+ E+ RD E+ ER + +E++++T E+ R++ER RE+ ++ R E E
Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 603
Query: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERAS 252
RE+E K +++ E + + E+ E E + + Q ++ +++ K + EK E++R
Sbjct: 604 MMREQEEKMQEQ--EEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 253 ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRET-ERKRERQRERERER 311
E +++K E E+ +++++ + Q+E+ + ++ ++ E++++T ++++ R+ E RER
Sbjct: 662 E---QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 312 ERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER 371
E+ + E E RE+E + Q + E+ +E+E E + + ++E + Q E+
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 778
Query: 372 ERERERDRQSAREREERERDRDRDRQKERER---QTEKDRDGQRETEKQRER-------- 420
E E+ ++++ E+EE+ RD++ + + E+ Q EK R + + Q E+
Sbjct: 779 EHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKM 838
Query: 421 -----------EKDRESERGRE-RGRER-EKQKGRERDRERQTDRQAGRQRK 459
EK E +G+E + RE+ EK +G+E Q ++ G++ K
Sbjct: 839 WGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 152 bits (385), Expect = 6e-37
Identities = 107/442 (24%), Positives = 234/442 (52%), Gaps = 28/442 (6%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERR--REKDRHRKR 91
QE R R + K ++ Q+E+ +++E+ E+E +++R +K++ ++
Sbjct: 447 QEEERIR---EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQ---KERERETEREGERGRDRQTDGQRE 148
++ +E++ ++ E+ D+E +EK+ RQ +E+E + + E+ RD++ +
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563
Query: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
ER +E+E++T Q E+ R++ER RE+ ++ R E E RE+E K +++ E
Sbjct: 564 EERMEKKTQEQEKKT----WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ--EE 617
Query: 209 GRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDR 268
+ + E+ E E + + Q ++ +++ K + EK E++R E +++K E E+ +
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE---QKEKLWEHEKMQ 674
Query: 269 DRDRDRRQKERERQTDRKRQRRTERDRET-ERKRERQRERERERERNRKRERERERERER 327
++++ + Q+E+ + ++ ++ E++++T ++++ R+ E RERE+ + E E RE+E
Sbjct: 675 EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEE 734
Query: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
+ Q + E+ +E+E E + + ++E + Q E+ E E+ ++++ E+EE
Sbjct: 735 KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEE 794
Query: 388 RERDRDRDR--QKERERQTEKDRDGQRE-----TEK---QREREKDRESERGRERGRERE 437
+ RD++ Q+E+ R E+ GQ E EK Q E+ +E + + + E
Sbjct: 795 KMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEE 854
Query: 438 KQKGRERDRERQTDRQAGRQRK 459
K +G+E Q ++ G++ K
Sbjct: 855 KMQGQEEKMREQEEKMRGQEEK 876
Score = 149 bits (376), Expect = 7e-36
Identities = 105/438 (23%), Positives = 228/438 (52%), Gaps = 30/438 (6%)
Query: 46 HKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKER 105
HK AD E ++++ R T + K++ +++ + + + KE
Sbjct: 192 HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKEL 251
Query: 106 ERQTDR---------------ERDRQREKERNRQKERERETE---REGERGRDRQTDGQR 147
+R+ +R E RQ E+ R ++K+ ++ E R+ ER R+ Q R
Sbjct: 252 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLRE-QEGKMR 310
Query: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207
E+E + +++R R+ ++E + Q + R+++ RE+ Q + + E+ E+E K ++ +
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370
Query: 208 RGRERER--ERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER-DKERER 264
R+ ER E+E + + ++ D+E + ER REK+ ER R E+ E+ +K RE
Sbjct: 371 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQVEKMREE 429
Query: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERE 324
++ +++++ R +E + Q + + + R ++ RE E Q E+ +++E N + E+E +
Sbjct: 430 KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 489
Query: 325 RER---ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQS 381
++R ++++ E+++ +E+E K Q E R++ G+E ++ +E+ RE+E
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE-KKMWRQEKMREQE---DQ 545
Query: 382 AREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441
E+EE+ RD+++ + ER +K ++ +++T Q E+ ++ E R RE+ E++
Sbjct: 546 MWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605
Query: 442 RERDRERQTDRQAGRQRK 459
RE++ + Q + ++++
Sbjct: 606 REQEEKMQEQEEKMQEQE 623
Score = 141 bits (355), Expect = 2e-33
Identities = 111/406 (27%), Positives = 218/406 (53%), Gaps = 44/406 (10%)
Query: 87 RHRKRDRHRE---RQRDR---EKERERQTDRERDRQR----------EKERNRQKERERE 130
RH+K DR+ E ++RD E R T+ E ++ E E++ + +E
Sbjct: 191 RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKE 250
Query: 131 TEREGERGR----DRQTDG-QRERERQRDAEKERERQTDRERQ---RQTERNRQKE---R 179
+R+ ER + QT+ Q E RQ + +E+E++ ++ + RQ ER R++E R
Sbjct: 251 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMR 310
Query: 180 EREKN--RQERRERERQRE-KENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
E+E+ RQE+R RE+++E +E + E R + RE+E E+ E E + Q ++ R+++
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQE-EQMQEQEEKMWEQEEKMREQEE 369
Query: 237 KTEREREKQAERE---RASERETERDKERERERD-RDRDRDRRQKERERQTD-----RKR 287
K R+ E+ E+E R E++ +ER E+D R R+++ R +E+E+ + R+
Sbjct: 370 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE 429
Query: 288 QRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
++ E++++T + E+ +E ER RER +K E E RE+E + + + + E+E K +
Sbjct: 430 KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 489
Query: 348 QTEMDRERNRQTGREGRRQAE----RERERERERDRQSAREREERERDRDRDRQKERERQ 403
Q + ++ + +E ++ E + E+ R+++ +E++ +++ R+++ + Q
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549
Query: 404 TEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQ 449
EK RD +++ Q ER + + E+ ++ + EK + ER RER+
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRERE 595
Score = 135 bits (341), Expect = 8e-32
Identities = 93/405 (22%), Positives = 203/405 (50%), Gaps = 25/405 (6%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
+R P +E + Q ++ + E+ R +E +EK+ +E R++E + +
Sbjct: 491 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 550
Query: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETER----EGERGRDRQT 143
+ RD+ ++ E+ ++ ++E+ ++E+ R++ER RE E+ E E R+++
Sbjct: 551 EKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 610
Query: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203
Q + E+ ++ E E+ ++E + Q + + E+E + QE + E+QR E K +
Sbjct: 611 KMQEQEEKMQEQE---EKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 204 RHSERGRERERERETE------------TETERKRQTDRERDRQRKTEREREKQAERERA 251
E+ +E+E+ +E E T+ + K+ D+E+ R+ ++ REREK+ E
Sbjct: 668 WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Query: 252 SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311
RE E + + E+ ++++ + E+E + + ++ E+ R E+K E+ E E+ +
Sbjct: 728 MMREQEEKMQEQEEKMQEQEEE--MWEQEEKMWEQEEKMWEQQRLPEQK-EKLWEHEKMQ 784
Query: 312 ERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER 371
E+ + E+E + + E+ R E + E+ R ++ +M + + G+E + + E+
Sbjct: 785 EQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEK 844
Query: 372 ---ERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRE 413
+ E+ ++ +E + RE++ Q+E+ R+ E+ GQ E
Sbjct: 845 MWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 114 bits (286), Expect = 2e-25
Identities = 79/350 (22%), Positives = 173/350 (49%), Gaps = 11/350 (3%)
Query: 11 DQLGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQ 70
+Q +W + D ++ +E ++ Q K D +++ R ++ RER ++ R+
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 71 TE---RETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKER 127
E RE + K + + EK + ++ + ++ +E+E + E+ ++E++ Q+
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 128 ERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQR--QTERNRQKEREREKNR 185
+ E+ E + ++ + +E+E + +++ E++T + ++ E+ R++E RE+ +
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK 720
Query: 186 QERRERERQREKENK---TEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER 242
+ R E E RE+E K E++ E+ E + E E E K + Q++ E
Sbjct: 721 KMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 780
Query: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
EK E+E+ E+E E+ +++E + ++ R Q+E+ R + K + E+ E K
Sbjct: 781 EKMQEQEKIWEQE-EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMW 839
Query: 303 RQRER--ERERERNRKRERERERERERERQRETERDREKERERKRKRQTE 350
Q E+ +E + K + + E+ RE+E + + ++ +E+E K + Q E
Sbjct: 840 GQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 112 bits (280), Expect = 1e-24
Identities = 90/354 (25%), Positives = 179/354 (50%), Gaps = 43/354 (12%)
Query: 148 ERERQRDAEKERERQTDRERQRQTE----------RNRQKEREREKNRQERRERERQREK 197
E +R A R ++ DR + T+ RN E +K E +E+ E
Sbjct: 180 ELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAES 239
Query: 198 ENKTEDRHSERGRERERER------ETETET---ERKRQTDRERDRQRKTEREREK---Q 245
E K+E + + + +R+ ER + +T T E RQ + R++++K ++ EK Q
Sbjct: 240 E-KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 298
Query: 246 AERERASE---RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
ER R E RE E R+ +R R+++++ R++E+E + ++ + + E+ +E E K
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358
Query: 303 RQRERERERERNRKRERER--ERERERERQRETERDREK----ERERKRKRQTEMDRERN 356
Q E+ RE+E R+ ER E+E++ Q + RD+E+ + ER R+++ M +
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 418
Query: 357 RQTGREGRRQAERERERERE-RDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETE 415
E R+ ++ +E+E++ RD++ + EER R+R++ ++E E E++ Q++ E
Sbjct: 419 MWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 478
Query: 416 KQRERE----------KDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
E+E + +E +E+ +E+E++ + ++ R + G+++K
Sbjct: 479 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 532
Score = 88.6 bits (218), Expect = 2e-17
Identities = 75/275 (27%), Positives = 144/275 (52%), Gaps = 22/275 (8%)
Query: 199 NKTEDRHSERGRERERERET-ETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257
+K DR+ E E +ER+ E R T+ E ++ +E+ AE E++ +
Sbjct: 192 HKKADRYIE---ELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNV 248
Query: 258 RDKERERERDR----DRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER 313
++ +R+ ER + + Q+E RQ + R++ ++ R+ E K RQ ER RE+E
Sbjct: 249 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE-KKIRKQEEKMWRQEERLREQEG 307
Query: 314 NRKRERERERERERERQRETERDREK---ERERKRKRQTEMDRERNRQTGREGR--RQAE 368
+ RE+E + RQ + R++EK E+E++ + Q E+ + + +E + Q E
Sbjct: 308 -----KMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE 362
Query: 369 RERERERERDRQSAR--EREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRES 426
+ RE+E + RQ R E+E++ R++++ + + ER E+D + + E+ RE+EK E
Sbjct: 363 KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 422
Query: 427 -ERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
E+ RE + +E++K E+ + + R+R++
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREK 457
Score = 48.1 bits (113), Expect = 2e-05
Identities = 46/194 (23%), Positives = 95/194 (48%), Gaps = 19/194 (9%)
Query: 279 RERQTDRKRQRRT-ERDR-ETERKRERQRERERERERNRKRER----ERERERERERQRE 332
R ++ DR + T ERD E R E +++ +E+ E E+ + +E
Sbjct: 191 RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKE 250
Query: 333 TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392
+R E+ + + QT +E + E R Q ++ R++E + RQ R RE+ + R
Sbjct: 251 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMR 310
Query: 393 DRD----RQKERERQTEKDRDGQRETEKQRERE--KDRESERGRERGREREKQKGRERDR 446
+++ RQ++R R+ EK+ +++E+E + +E E+ +E+E++ + ++
Sbjct: 311 EQEEKMWRQEKRLREQEKEL-------REQEKELREQKELREQEEQMQEQEEKMWEQEEK 363
Query: 447 ERQTDRQAGRQRKR 460
R+ + + RQ +R
Sbjct: 364 MREQEEKMWRQEER 377
Score = 44.3 bits (103), Expect = 3e-04
Identities = 40/194 (20%), Positives = 90/194 (46%), Gaps = 8/194 (4%)
Query: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR----ET 333
E +R R + DR E + + E RN E +++ +++ E+
Sbjct: 180 ELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAES 239
Query: 334 ERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRD 393
E+ + ++ KR+ E + Q + Q E R+ E R+++ ++E + R
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQV-QTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ 298
Query: 394 RDRQKERE-RQTEKDRDGQRETEKQREREKD-RESERG-RERGREREKQKGRERDRERQT 450
+R +E+E + E++ R+ ++ RE+EK+ RE E+ RE+ RE+++ + E+
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358
Query: 451 DRQAGRQRKRSTLY 464
+++ + + ++
Sbjct: 359 EQEEKMREQEEKMW 372
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 170 bits (430), Expect = 4e-42
Identities = 107/419 (25%), Positives = 228/419 (54%), Gaps = 18/419 (4%)
Query: 55 ERNRQKERERRREKRQTERETDRKRERR---REKDRHRKRDRHRERQRDREKERERQTDR 111
E R++E++ R+++ + R+ +R RE+ RE++ +R R R++++E + + R
Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
Query: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
E+ + RE+E Q++ E+ E+E E+ R+++ R+ ER + EK+ Q + R ++
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQE-EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Q ER REK + RE+E+ E+E K ++ ER RERE++ E ET R+++ +
Sbjct: 360 RMWEQDERLREKE-ERMREQEKMWEQEEKMQEE--ERIREREKKMREEEETMREQEEKMQ 416
Query: 232 RDRQRKTEREREKQAERERASERET---ERDKERERERDRDRDRDRRQKERERQTDRKRQ 288
+ + E+E EK+ +++R E++ E++K +E+E ++ + + E K+
Sbjct: 417 KQEENMWEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475
Query: 289 RRTERDRETERKRERQRERERERERNRKRERER-----ERERERERQRETERDREKERER 343
R E+ RE E + Q E+ R++E+ + ER ER RE+E + ++ ++ E+
Sbjct: 476 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK 535
Query: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERE--RDRQSAREREERERDRDRDRQKERE 401
R+ + ++E+ E R+ ER RERE++ + + RE+EE+ ++++ +++ E
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Query: 402 RQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
+ E++ Q + EK E+E+ + ++ +E+E+ + ++ ++ + + Q ++
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Score = 168 bits (426), Expect = 1e-41
Identities = 108/444 (24%), Positives = 234/444 (52%), Gaps = 36/444 (8%)
Query: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERE 106
++ +G RE Q+E+ RR+EKR E+E + + + + +++ + R++ + Q EK E
Sbjct: 265 REQEGKMRE---QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWE 321
Query: 107 RQTD-RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE---KERERQ 162
++ RE++ + ++ R E+E++ + ++ RD++ + ER R+ E +E+E+
Sbjct: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
Query: 163 TDRERQRQTE---RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRER------- 212
++E + Q E R R+K+ E+ +E + Q+++EN E E ++R
Sbjct: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
Query: 213 --ERERETETETERKRQTDRERDRQ-------RKTEREREKQAERERASERETERDKER- 262
E+E+ E E + Q ++ RD++ + +E+ ++ E + + E RD+E+
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501
Query: 263 ---ERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR----ERERERERNR 315
+ ER ++D R+KE + +K ++ E+ RE ++ +E+++ + E+ RE R
Sbjct: 502 MWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER 561
Query: 316 KRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERER 375
RERE++ E E RE E +++ E+ R+++ +M + + +E + + E+ E+
Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 621
Query: 376 ERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRE 435
E + +E+EE +++ Q++ E+ E++ + + EK RE+E+ + + + R +E
Sbjct: 622 E-EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
Query: 436 REKQKGRERDRERQTDRQAGRQRK 459
EK +G+E Q ++ G++ K
Sbjct: 681 -EKMQGQEEKMREQEEKMRGQEEK 703
Score = 167 bits (423), Expect = 3e-41
Identities = 109/452 (24%), Positives = 229/452 (50%), Gaps = 27/452 (5%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
QE R + K + R+ R +E+E + +++ + KR R +EK+ +
Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 94 HRERQRDREKERERQTDRER-----DRQREKERNRQKERERETEREGE-RGRDRQTDGQR 147
RE+++ RE+E + Q E+ ++ RE+E ++ ER E+E + R ++++ Q
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 358
Query: 148 ERERQRD---AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
ER ++D EKE + + Q E+ +++ER RE+ ++ R E E RE+E K + +
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 418
Query: 205 HSERGRERERERETETETERKR---QTDRERDRQRKTEREREKQAERER--ASERETERD 259
+ E+E + + E+K + ++ ++++ K + EK ++E E++ R
Sbjct: 419 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
Query: 260 KERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER-------ERERE 312
++ + D+ +++ + +++E++ + +R E+D K ER RE+ E+ RE
Sbjct: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
Query: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER--- 369
+ +E+E++ + E+ RE ER RE+E++ + + + ++E Q E R+ E
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW 598
Query: 370 ERERERERDRQSAREREER--ERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESE 427
E+E + + + E+EE+ E++ + Q++ E E++ Q + EK E+E+ +
Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 658
Query: 428 RGRERGREREKQKGRERDRERQTDRQAGRQRK 459
+ R +E EK +G+E Q ++ G++ K
Sbjct: 659 EEKMREQE-EKMQGQEEKMREQEEKMQGQEEK 689
Score = 167 bits (422), Expect = 3e-41
Identities = 106/462 (22%), Positives = 232/462 (50%), Gaps = 28/462 (6%)
Query: 58 RQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREK---ERERQTDRERD 114
RQ+ER +EK+ E+E + + R ++ + ER R++EK + E+ + ER
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
Query: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
R+REK+ ++E RE E + ++ + + + + +Q+ +++E+ ++E+ ++ E
Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
Query: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
++ E+ ++++E +E++ ++ K ++ + + E+ R+ E + + + E+D
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE 514
Query: 235 QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294
+ + + ER ++ ++ E + +K+ + + + D++ + +E ER +R+++ R E +
Sbjct: 515 RLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 574
Query: 295 --RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
RE E K + Q E+ RE+E + E+ +E+E + + E+ E+E E K + Q EM
Sbjct: 575 MMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMM 634
Query: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
E +E + Q + E+ E+E + RE+EE+ R+++ Q + E+ E++ Q
Sbjct: 635 WE------QEEKMQEQEEKMWEQE---EKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
Query: 413 ETEKQREREKDRESERGRERGRE------REKQKGRERDRERQTDRQAGRQRKRSTLYVN 466
+ EK RE+E+ + + G+E EK G+E RE++ + +++ + L +
Sbjct: 686 QEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEH 745
Query: 467 P--------PPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAA 500
PP + + P G + SP+D A
Sbjct: 746 EERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQDNPTA 787
Score = 158 bits (399), Expect = 2e-38
Identities = 104/407 (25%), Positives = 212/407 (52%), Gaps = 22/407 (5%)
Query: 53 DRERNRQKERERRREKRQTERETD--RKRERRREKDRHRKRDRHRERQRDREKERERQTD 110
+++ Q+++ R +E+R E++ K ER RE+++ +++ + ++ +R +ERE++
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEE-KMQEEERIREREKKMR 402
Query: 111 RERDRQREKERNRQKERERETEREGERGRDRQTDGQRER--ERQRDAEKERERQTDRERQ 168
E + RE+E QK+ E E+E + + ++ Q+E+ E+++ E+E + E+
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 462
Query: 169 RQTER---------NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE 219
R E ++K RE+E E+ E+ R +E++ ++ ER RE+E
Sbjct: 463 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER 522
Query: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER 279
++K E+ R+ K +E+EK+ + RE ER +ERE++ + + R Q+E+
Sbjct: 523 MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 582
Query: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
++ + K + + E+ E E K + Q E+ E+E + E ++ +E+E + ++ +
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ 642
Query: 340 ERERKRKRQTEMDRE-----RNRQTGREGRRQAERERERERERDRQSAREREERERDRDR 394
E+E K Q E RE R ++ +G+ + RE+E + + + RE+EE+ R ++
Sbjct: 643 EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEE 702
Query: 395 DR--QKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQ 439
Q+E+ E+ GQ E ++ ER +D + E+ +ER E E++
Sbjct: 703 KMWGQEEKMWGQEEKMWGQEEMREKEERIRD-QKEKMQERLPEHEER 748
Score = 154 bits (389), Expect = 2e-37
Identities = 114/444 (25%), Positives = 234/444 (52%), Gaps = 33/444 (7%)
Query: 46 HKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKER 105
HK AD E ++++ R T + K++ +++ R + + + KE
Sbjct: 154 HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKEL 213
Query: 106 ERQTDR---------------ERDRQREKERNRQKERERETE---REGERGRDRQTDGQR 147
+R+ +R E RQ E+ R ++K+ ++ E R+ ER R+++ +
Sbjct: 214 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE 273
Query: 148 ERERQRDAEKE-RERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206
+ E+ R EK RE++ + Q + R ++K RE+E+ QE+ E+ ++E++ + ++
Sbjct: 274 QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM 333
Query: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
R ER E+E + + ++ D+E + ER REK+ ER R E+ E++ E+ +E
Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQE-EKMQEE 391
Query: 267 DRDRDRDRRQKERE---RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER 323
+R R+R+++ +E E R+ + K Q++ E E E K +Q+ ++E+ ++E+ +E+
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 324 ERERERQRETERDREKE--RERKRKRQTEMDRERNRQTGREGRRQAERERERERERDR-- 379
E + Q E RD+E+ +E+K RQ +M RE+ Q + + ++E++ + +R
Sbjct: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKM-REQEDQMWEQEEKMRDQEQKMWDQEERMW 510
Query: 380 -QSAREREERERDRDRDR---QKERERQTEKDRDGQRETEKQREREKDRESERGRERGRE 435
Q R RE+ ER R++ + Q+E+ R+ +K ++ +++T Q E+ ++ E R RE+
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR 570
Query: 436 REKQKGRERDRERQTDRQAGRQRK 459
E++ RE++ + Q + R+++
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQE 594
Score = 150 bits (380), Expect = 2e-36
Identities = 110/442 (24%), Positives = 233/442 (52%), Gaps = 38/442 (8%)
Query: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRR-----------EKDRHRKRDRHR 95
K + + +E+ R E E+ E + +E RK ER + +++ R+ + R
Sbjct: 186 KKKNAELQEKLRLAESEKS-EIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244
Query: 96 ERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDA 155
E+++ K+ E+ R+ +R RE+E + +E+E + R+ +R R+++ + + + + R+
Sbjct: 245 EQEKKIRKQEEKMW-RQEERLREQE-GKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
Query: 156 EKERERQTDRERQRQ---TERNRQKEREREKNRQERR--ERERQ-REKENKTEDRHSERG 209
+K RE++ + Q + + + +E+E + RQE R E+E+Q RE+E K D+
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 362
Query: 210 RERERERETETETERKRQTDRERDRQRK-TEREREKQAERERASERETERDKERERERDR 268
+ ER RE E ER R+ ++ +++ K E ER ++ E++ E ET R++E + ++
Sbjct: 363 EQDERLREKE---ERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
Query: 269 DRDRDRRQKERERQ----------TDRKRQRRTERDRETERKRERQRERERERERNRKRE 318
+ ++ +KE ++Q K Q + E+ E E K Q E + ++ ++E
Sbjct: 420 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479
Query: 319 RERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERD 378
+ RE+E + Q E RD+E++ + +R E D ER R+ R Q + ++ E+ R+
Sbjct: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD-ERLREKEERMREQKKMWQQEEKMRE 538
Query: 379 RQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREK 438
+ +E+E++ D++ ++ +E ER E+++ + E E RE+E+ + + E+ RE+E+
Sbjct: 539 EKKTQEQEKKTWDQE-EKMREEERMREREKKMREEEEMMREQEEKMQEQ--EEKMREQEE 595
Query: 439 QKGRERDRERQTDRQAGRQRKR 460
+ + ++ ++ + + Q ++
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEK 617
Score = 142 bits (359), Expect = 7e-34
Identities = 100/394 (25%), Positives = 213/394 (54%), Gaps = 28/394 (7%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
R R + + + + + ++R R R+K + RE+ +T RE + K + ++E++
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEERIREREK---KMREEEETMREQEEKMQ-KQEENM 422
Query: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETERE-GERGRDRQTDGQ 146
+ ++ ++QR E ++E+ ++E+ +++E++ Q+E+ R+ E G+ + + +
Sbjct: 423 WEQEEKEWQQQRLPE-QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481
Query: 147 RERERQRDAEKERERQTDRERQRQTERN-RQKEREREKNRQERRERERQREKENKTEDRH 205
RE+E Q ++E+ R +++ Q ER Q ER REK ER R+++K + E++
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK-----EERMREQKKMWQQEEKM 536
Query: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE 265
E + +E+E++T + E+ R+ +R R+R++K E E E+E + + E+ +E+E +
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596
Query: 266 RDRDRDRDRRQKER---------ERQTDRKRQRRTERDRETERKRERQRERERERERNRK 316
++ + Q+E+ E++ + K Q + E E E K + Q E+ E+E +
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656
Query: 317 RERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER---ER 373
+ E+ RE+E + Q + E+ RE+E E+ + ++ +M + + G+E + + E+ +
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQE-EKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQE 715
Query: 374 ERERDRQSAREREERERDRDRDRQKERERQTEKD 407
E+ ++ RE+EER RD+ ++K +ER E +
Sbjct: 716 EKMWGQEEMREKEERIRDQ---KEKMQERLPEHE 746
Score = 127 bits (319), Expect = 3e-29
Identities = 98/403 (24%), Positives = 209/403 (51%), Gaps = 36/403 (8%)
Query: 88 HRKRDRHRE---RQRDR-EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143
H+K DR+ E ++RD E R T + +++ ++K R E+E+ + ++
Sbjct: 154 HKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKEL 213
Query: 144 DGQRERERQRDAEKERERQTDRERQ-RQTERNRQKEREREKNRQER-RERERQREKENKT 201
+R+ ER + + + T +E RQ E R++E++ K ++ R+ ER RE+E K
Sbjct: 214 --KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 271
Query: 202 EDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE-RASERETERDK 260
++ + R+ +R RE E E + + RE+ + R+ E + ++Q E+ E+ E+++
Sbjct: 272 REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331
Query: 261 ERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
+ R+ +R +++++ +E+E++ + +R E+D K ER RE+E+ E + E
Sbjct: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE-----QEE 386
Query: 321 RERERERERQRE----TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376
+ +E ER R+RE E + +E+E K ++Q E E+ + ++ R ++E+ E+E
Sbjct: 387 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446
Query: 377 RDRQSAR---EREERERDRD---------------RDRQKERERQTEKDRDGQRETEKQR 418
+ ++ E+EE+ RD++ R+++ + Q EK RD +++ Q
Sbjct: 447 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
Query: 419 EREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRS 461
ER +++ + R RE++K +++ + + +++ Q K++
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Score = 123 bits (309), Expect = 4e-28
Identities = 131/476 (27%), Positives = 223/476 (46%), Gaps = 65/476 (13%)
Query: 31 PGSQESPRRRGLGQAHKDADGDDRERN------RQKERERRREKRQTERETDRKRERRRE 84
P E R+ L +A K D R+ N R + ++++ T ET
Sbjct: 11 PMMSEKTRQNKLAEAKKKFT-DYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSP 69
Query: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQR---EKERNRQKERERETEREGERGRDR 141
+D + +H+E R RE E + T R Q+ E ++ R+ E +G G +
Sbjct: 70 EDEKKASHQHQEALR-REIEAQDHTIRILTCQKTELETALYYSQDAARKFE-DGNLGESK 127
Query: 142 QTDGQR--------ERERQRDAEKERERQTDRERQRQTE----------RNRQKEREREK 183
G+ E +R A ++ DR + T+ RN E +K
Sbjct: 128 DLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKK 187
Query: 184 NRQERRERERQREKENKTEDRHSERGRERERER------ETETET---ERKRQTDRERDR 234
E +E+ R E E K+E + + + +R+ ER + +T T E RQ + R++
Sbjct: 188 KNAELQEKLRLAESE-KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQ 246
Query: 235 QRKTEREREK---QAERERASE---RETERDKERERERDRDRDRDRRQKERERQTDRKRQ 288
++K ++ EK Q ER R E RE E R+ +R R+++++ R++E+E + +K +
Sbjct: 247 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLR 306
Query: 289 RRTERDRETERKRERQRERERERERNRKRERER--ERERERERQRETERDREK---ERER 343
+ E+ +E E K Q E+ RE+E R+ ER E+E++ Q + RD+E+ E++
Sbjct: 307 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 366
Query: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERER- 402
+ + + E RE+ + +E + Q E ER RERE+ RE EE R+++ QK+ E
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQ-EEERIREREK---KMREEEETMREQEEKMQKQEENM 422
Query: 403 --QTEKDRDGQR---ETEKQREREKDRESE----RGRERGREREKQKGRERDRERQ 449
Q EK+ QR + EK E+EK +E E E+ R++E+ G+E+ RQ
Sbjct: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
Score = 112 bits (279), Expect = 1e-24
Identities = 73/320 (22%), Positives = 163/320 (50%), Gaps = 7/320 (2%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
+R P +E + Q ++ + E+ R +E +EK+ +E R++E + +
Sbjct: 433 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492
Query: 88 HRKRDRHRER--QRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG 145
+ RD+ ++ Q +R E++ + + +R RE+++ Q+E + E++ + ++++T
Sbjct: 493 EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQE-QEKKTWD 551
Query: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH 205
Q E+ R+ + +ERE++ RE + +K +E+E+ +E + E+ E+E K +++
Sbjct: 552 QEEKMREEERMREREKKM-REEEEMMREQEEKMQEQEEKMRE--QEEKMWEQEEKMQEQE 608
Query: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE 265
+ + E+ E E E + + Q + +++ K + + EK E+E + E+ +E+E +
Sbjct: 609 EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Query: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERE-RERERNRKRERERERE 324
++ R Q+E+ + + K + + E+ R E K Q E+ + E+ +E RE+E
Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKE 728
Query: 325 RERERQRETERDREKERERK 344
Q+E ++R E E +
Sbjct: 729 ERIRDQKEKMQERLPEHEER 748
Score = 79.3 bits (194), Expect = 9e-15
Identities = 52/225 (23%), Positives = 111/225 (49%), Gaps = 11/225 (4%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTE-----RETDRKRERRREKDRH 88
+E R Q + D E+ R++ER R REK+ E RE + K + + EK R
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 89 RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148
++ + ++ +E+E + E+ ++E+E Q++ E E+E E+ ++++ +
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE-EKMQEQEEKMWEQ 651
Query: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
E+ R+ E++ RE++ + + +K RE+E+ Q + E+ R++E++ + ++
Sbjct: 652 EEKMREQEEKM-----REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWG 706
Query: 209 GRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
E+ +E + + + + ER R +K + + ER SE
Sbjct: 707 QEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSE 751
Score = 69.7 bits (169), Expect = 7e-12
Identities = 76/338 (22%), Positives = 152/338 (44%), Gaps = 37/338 (10%)
Query: 151 RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGR 210
R D +K++ +E E E++ + Q + R+ E ++ T + +
Sbjct: 43 RATDTKKKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKT 102
Query: 211 ERERERETETETERKRQTDR---ERDRQRKTEREREKQAERERASERETERDKERER--- 264
E E + RK + +D + E +RA + K+ +R
Sbjct: 103 ELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIE 162
Query: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER- 323
E ++RD + R T+ + +++ +E R E ++ + + KR+ ER +
Sbjct: 163 ELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKF 222
Query: 324 ----------ERERERQRETERDREKE---------RERKRKRQTEMDRERNRQTGREGR 364
+ E RQ E R++EK+ R+ +R R+ E + R+ + R
Sbjct: 223 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE---GKMREQEEKMR 279
Query: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD- 423
RQ +R RE+E+E RE+E+ R++ + R++E + Q ++++ ++E EK RE+E+
Sbjct: 280 RQEKRLREQEKE-----LREQEKELREQKKLREQEEQMQEQEEKMWEQE-EKMREQEEKM 333
Query: 424 -RESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
R+ ER E+ ++ +Q+ + RD+E + Q R R++
Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 371
Score = 57.0 bits (136), Expect = 5e-08
Identities = 83/341 (24%), Positives = 144/341 (42%), Gaps = 44/341 (12%)
Query: 148 ERERQRDAEKERERQTDRER-------QRQTERNRQKEREREKNRQERRERERQREKENK 200
E+ RQ + +++ TD + R T+ ++K E E E K
Sbjct: 15 EKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSEGCHSPEDEKK 74
Query: 201 TEDRHSERGRERERERETET-------ETERKRQTDRERDRQRKTER----EREKQAERE 249
+H E R RE E + T +TE + +D RK E E + A R
Sbjct: 75 ASHQHQEALR-REIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRL 133
Query: 250 R-----ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
A E + + DR + KER+ + + R T + E ++K
Sbjct: 134 HHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALS-LELYRNTITNEELKKKNAEL 192
Query: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR 364
+E+ R E E+ + +E +R E+ + + QT +E + E R
Sbjct: 193 QEK--------LRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244
Query: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQ----RETEKQ-RE 419
Q ++ R++E + RQ R RE+ + R+ Q+E+ R+ EK Q RE EK+ RE
Sbjct: 245 EQEKKIRKQEEKMWRQEERLREQEGKMRE---QEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 420 REKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
++K RE E E+ +E+E++ + ++ R+ + + RQ +R
Sbjct: 302 QKKLREQE---EQMQEQEEKMWEQEEKMREQEEKMWRQEER 339
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 167 bits (422), Expect = 3e-41
Identities = 96/327 (29%), Positives = 174/327 (53%), Gaps = 16/327 (4%)
Query: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDR 165
++ D++ + K + KE E +R ER R R +R +R + R R R
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSP--RRSLSPRRSPRRSRSRSHHR 283
Query: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
E + +R+ ERE+E+ R ER +ER++E+ R +RG ER R R E R
Sbjct: 284 EGHGSSSFDRELEREKERQRLEREAKEREKERRRS---RSIDRGLERRRSRSRERHRSRS 340
Query: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
R DR+ DR+ +R+RE++ E ER R+ + DKER ER+++R+R R + + +R
Sbjct: 341 RSRDRKGDRR---DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGE 397
Query: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR---ETERDREKERE 342
+++ + D++ R R+ +R+ ++E++ +R R RER + R R R R + R R KE+
Sbjct: 398 VEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRER-KHRSRSRSRNAGKRSRSRSKEKS 456
Query: 343 RKRKRQTEMDRERNRQTGREGRRQA-ERERERERERDRQSARER---EERERDRDRDRQK 398
K K +++ + ++G +GR + E+ ++RE ++ +R+R +ER RD K
Sbjct: 457 SKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSK 516
Query: 399 ERERQTEKDRDGQRETEKQREREKDRE 425
++ + ++ R E E Q ++ K+++
Sbjct: 517 DQSDKHDRRRSQSIEQESQEKQHKNKD 543
Score = 164 bits (414), Expect = 3e-40
Identities = 98/321 (30%), Positives = 162/321 (50%), Gaps = 25/321 (7%)
Query: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206
R R+ ++D KE + DR +R+ R+R R R RR R R +E H
Sbjct: 236 RPRKIKKDG-KEGAEEIDRHVERR--RSRSPRRSLSPRRSPRRSRSRSHHREG-----HG 287
Query: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
+RE ERE E + R + +ER+++R+ R ++ ER R+ RE + R R R
Sbjct: 288 SSSFDRELEREKERQ--RLEREAKEREKERRRSRSIDRGLERRRSRSRE----RHRSRSR 341
Query: 267 DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR-------ER 319
RDR DRR ++RER+ + +R RR +RD + ER ER++ERER RER++++ E+
Sbjct: 342 SRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEK 401
Query: 320 ERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDR 379
+ + +++ R R+ +RD +KE++ R R RER ++ R +R R R +E+
Sbjct: 402 KHKEDKDDRRHRDDKRDSKKEKKHSRSR----SRERKHRSRSRSRNAGKRSRSRSKEKSS 457
Query: 380 QSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQ 439
+ E +E+ R R + R EK + + K++ R++ R ER +R K
Sbjct: 458 KHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKD 517
Query: 440 KGRERDRERQTDRQAGRQRKR 460
+ + DR R + Q K+
Sbjct: 518 QSDKHDRRRSQSIEQESQEKQ 538
Score = 163 bits (413), Expect = 4e-40
Identities = 94/326 (28%), Positives = 172/326 (52%), Gaps = 9/326 (2%)
Query: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERE 106
K+ D + R R+ +++ + + +R +R+R R + +R R R R +E
Sbjct: 227 KNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGH 286
Query: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166
+ +R+ +REKER R ERE + ERE ER R R D ER R R E+ R R R+
Sbjct: 287 GSSSFDRELEREKERQRL-EREAK-EREKERRRSRSIDRGLERRRSRSRERHRSRSRSRD 344
Query: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226
R+ R+R +ERE+E R RR+R+ +E+ N+ E + ER RER +E+ + E E K+
Sbjct: 345 RKGD-RRDRDREREKENERGRRRDRDYDKERGNERE-KERERSRERSKEQRSRGEVEEKK 402
Query: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
+ + DR+ + ++ R+ + E++ + R ER K R R R R+ + R + +E+ + K
Sbjct: 403 HKEDKDDRRHRDDK-RDSKKEKKHSRSRSRER-KHRSRSRSRNAGKRSRSRSKEKSSKHK 460
Query: 287 RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK 346
+ +++ +R R + R E+++KRE +E+ R+R R ER +++ +
Sbjct: 461 NE---SKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKD 517
Query: 347 RQTEMDRERNRQTGREGRRQAERERE 372
+ + DR R++ +E + + + ++
Sbjct: 518 QSDKHDRRRSQSIEQESQEKQHKNKD 543
Score = 162 bits (409), Expect = 1e-39
Identities = 94/324 (29%), Positives = 162/324 (50%), Gaps = 12/324 (3%)
Query: 91 RDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERE 150
+ R R+ ++D KE + DR +R+R + R R R R R+ G +
Sbjct: 234 KTRPRKIKKDG-KEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFD 292
Query: 151 RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGR 210
R+ + EKER+R ++R+ ER R + +R R+ R RER R + + + R R
Sbjct: 293 RELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDR 352
Query: 211 ERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDR 270
+RERE+E E R R D+ER +R+ ERER ++ +E+ S E E K +E + DR
Sbjct: 353 DREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRH 412
Query: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ 330
D+R ++E++ R R R + + + +R R R +E++ K + E +E+ +R
Sbjct: 413 RDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNE-SKEKSNKRS 471
Query: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERER 390
R + R E+ +KR+ +E++ R+ R +ER +RD ++++ ++
Sbjct: 472 RSGSQGRTDSVEKSKKREHSPSKEKS--------RKRSRSKERSHKRDHSDSKDQSDK-H 522
Query: 391 DRDRDRQKERERQTEKDRDGQRET 414
DR R + E+E Q EK + ET
Sbjct: 523 DRRRSQSIEQESQ-EKQHKNKDET 545
Score = 158 bits (399), Expect = 2e-38
Identities = 88/306 (28%), Positives = 153/306 (50%), Gaps = 8/306 (2%)
Query: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS-ERGRERERERET 218
++ D++ + + + ++ +E + ER R R R S R R R RE
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREG 285
Query: 219 ETETERKRQTDRERDRQR--KTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276
+ R+ +RE++RQR + +EREK+ R R+ +R ER + R RER R R R R +
Sbjct: 286 HGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDR 345
Query: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE-RERERERQRETER 335
K R DR+R++ ER R +R +++R ERE+ER R RER +E R R +++ +
Sbjct: 346 KGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKE 405
Query: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
D++ R R KR ++ +++ +R RE + ++ +R R ++E+ + ++ ++
Sbjct: 406 DKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKE 465
Query: 396 RQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAG 455
+ +R R + R E K+RE +E R R R +ER +RD D+
Sbjct: 466 KSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKER----SHKRDHSDSKDQSDK 521
Query: 456 RQRKRS 461
R+RS
Sbjct: 522 HDRRRS 527
Score = 156 bits (394), Expect = 6e-38
Identities = 84/285 (29%), Positives = 162/285 (56%), Gaps = 11/285 (3%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGD---DRERNRQKERERRREKRQTERETDRKRERRRE 84
RR + SPRR H++ G DRE R+KER+R E+ ERE +R+R R +
Sbjct: 264 RRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRL-EREAKEREKERRRSRSID 322
Query: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
+ R+R R RER R R + R+R+ DR RDR RE+E+ ++ R R+ + + ERG +R+ +
Sbjct: 323 RGLERRRSRSRERHRSRSRSRDRKGDR-RDRDREREKENERGRRRDRDYDKERGNEREKE 381
Query: 145 GQRERERQRDAEKERERQTDRERQ-RQTERNRQKEREREKNRQERRERERQREKENKTED 203
+R RER ++ E + + ++ + R+R +R+ +K ++ R R R+R+ +++
Sbjct: 382 RERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRS 441
Query: 204 RHS-ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKER 262
R++ +R R R +E+ ++ + E K ++++ R R + R E+ + E ++K R
Sbjct: 442 RNAGKRSRSRSKEKSSKHKNESKEKSNK---RSRSGSQGRTDSVEKSKKREHSPSKEKSR 498
Query: 263 ERERDRDRDRDRRQKERERQTDRKRQRRTER-DRETERKRERQRE 306
+R R ++R R + + Q+D+ +RR++ ++E++ K+ + ++
Sbjct: 499 KRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
Score = 127 bits (318), Expect = 4e-29
Identities = 85/257 (33%), Positives = 133/257 (51%), Gaps = 15/257 (5%)
Query: 233 DRQRKTEREREKQAERERASE--RETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
D+Q KT + K+ +E A E R ER + R R R R + R R R+
Sbjct: 230 DQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPR-RSRSRSHHREGHGS 288
Query: 291 TERDRETERKRERQR----ERERERERNRKRERERERERERERQRETERDREKERERKRK 346
+ DRE ER++ERQR +ERE+ER R R +R ER R R RE R R + R+RK
Sbjct: 289 SSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGD 348
Query: 347 RQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK 406
R+ + DRER ++ R RR + ++ER ER+++ R RE + R R +E++ + +K
Sbjct: 349 RR-DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDK 407
Query: 407 D----RDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRST 462
D RD +R+++K+++ + R ER + R R R + G+ R R R ++ + + + S
Sbjct: 408 DDRRHRDDKRDSKKEKKHSRSRSRER-KHRSRSRSRNAGK-RSRSRSKEK-SSKHKNESK 464
Query: 463 LYVNPPPRTARSGVVQS 479
N R+ G S
Sbjct: 465 EKSNKRSRSGSQGRTDS 481
Score = 116 bits (291), Expect = 5e-26
Identities = 65/259 (25%), Positives = 134/259 (51%), Gaps = 23/259 (8%)
Query: 29 RRPGSQESPRRRGL----GQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
R +E RRR G + + +R R+R + R+R+ ++R +RE +++ ER R
Sbjct: 306 REAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRR 365
Query: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
+DR ++R ER+++RE+ RER +E+ + E E + KE D
Sbjct: 366 RDRDYDKERGNEREKERERSRER--SKEQRSRGEVEEKKHKE---------------DKD 408
Query: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
+R R+ +RD++KE++ R R+R+ R+R + R K R R +E+ + +N+++++
Sbjct: 409 DRRHRDDKRDSKKEKKHSRSRSRERK-HRSRSRSRNAGK-RSRSRSKEKSSKHKNESKEK 466
Query: 205 HSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERER 264
++R R + R E +KR+ +++ RK R +E+ +R+ + ++ +R R
Sbjct: 467 SNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRR 526
Query: 265 ERDRDRDRDRRQKERERQT 283
+ +++ +Q + + +T
Sbjct: 527 SQSIEQESQEKQHKNKDET 545
Score = 106 bits (265), Expect = 5e-23
Identities = 73/241 (30%), Positives = 120/241 (49%), Gaps = 17/241 (7%)
Query: 21 TIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERER-RREKRQTERETDRKR 79
+I RRR S+E R R + K D DR+R R+KE ER RR R ++E +R
Sbjct: 320 SIDRGLERRRSRSRERHRSRSRSRDRK-GDRRDRDREREKENERGRRRDRDYDKERGNER 378
Query: 80 ERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGR 139
E+ RE+ R R ++ +R R +E++ + D++ R R+ +R+ +KE++ R ER
Sbjct: 379 EKERERSRERSKE---QRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRER-- 433
Query: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN 199
R R R R+A K R R +E+ + +N KE+ +++R + R EK
Sbjct: 434 -----KHRSRSRSRNAGK-RSRSRSKEKSSK-HKNESKEKSNKRSRSGSQGRTDSVEKSK 486
Query: 200 KTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERD 259
K E HS +E+ R+R E KR +D+ K +R R + E+E ++ +D
Sbjct: 487 KRE--HSP-SKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKD 543
Query: 260 K 260
+
Sbjct: 544 E 544
Score = 95.9 bits (237), Expect = 9e-20
Identities = 64/224 (28%), Positives = 114/224 (50%), Gaps = 8/224 (3%)
Query: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363
Q+ +++ + ++ ++ +E E R ER R + R + R R+R REG
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREG 285
Query: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD 423
+ +RE ERE++RQ ERE +ER+++R R + +R E+ R RE + R R +D
Sbjct: 286 HGSSSFDRELEREKERQRL-EREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRD 344
Query: 424 RESER-GRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPN 482
R+ +R R+R RE+E ++GR RDR+ +R R+++R + +R G V+ +
Sbjct: 345 RKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSR-GEVEEKKH 403
Query: 483 RPTRGIR-----WKSSPEDPKAASTRFPWGRPAKASRGRVAGRR 521
+ + R + S ++ K + +R + SR R AG+R
Sbjct: 404 KEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKR 447
Score = 29.6 bits (65), Expect = 8.3
Identities = 14/49 (28%), Positives = 27/49 (55%)
Query: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERET 75
SR+R S+E +R + +D DR R++ E+E + ++ + + ET
Sbjct: 497 SRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDET 545
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 166 bits (419), Expect = 7e-41
Identities = 111/434 (25%), Positives = 238/434 (54%), Gaps = 28/434 (6%)
Query: 44 QAHKDADGDDRERNRQKERERRRE-----------KRQTERETDRKRERRREKDRHRKRD 92
Q ++ + E+ R++E + RR+ +RQ E +++ + RR+++ +++
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 376
Query: 93 RHRERQRDREKERERQTDRERDRQREKERNRQKERERETE---REGERGRDRQTDGQRER 149
RQ + E+E + ++ E+E+ R++E +R+ E RE E+ ++++ R+
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKN-RQERRERERQREKENKTEDRHSER 208
E+ R+ E E+ R+ +++ RQ E+ ++E+ RE+ RQE+ E RQ EK ++ E+ ++
Sbjct: 437 EKIREQE-EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
Query: 209 GRERERERETETETERK-RQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
+ E+E + + E+ RQ ++ R+++ K RE+E++ R+ RE E + RE E+
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKI-REQEEKMWRQEEKIREQE-EMWREEEKM 553
Query: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER-----E 322
++++ +++R+ Q D K R+ E+ RE E K RQ E+ RE+E R+ + E+ E
Sbjct: 554 HEQEKIWEEEKRQEQED-KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
Query: 323 RERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSA 382
+ RE+E + + + ++ +E+E K + Q EM +E+ + G + + E+E + + + +
Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
Query: 383 REREERERDRDRDRQKERERQTEKDRDGQRETEKQRER---EKDRESERGRERGREREKQ 439
+E + RE+++ Q+E+ R+ E+ Q E ++E E++ + + E+ R +E++
Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
Query: 440 KGRERDRERQTDRQ 453
+ R RQ + +
Sbjct: 733 MWEQEVRLRQQEEK 746
Score = 162 bits (411), Expect = 6e-40
Identities = 108/410 (26%), Positives = 221/410 (53%), Gaps = 16/410 (3%)
Query: 57 NRQKERE--RRREKRQTERETDRKRER--RREKDRHRKRDRHRERQRDREKERERQTDRE 112
N+Q+E + R+ EK Q E +++E R ++++ R+++ RQ + E+E + R+
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ---R 169
+ EKE +++ E E+E + R + ++E + + EK E++ RE++ +
Sbjct: 355 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 414
Query: 170 QTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETET-ETERKRQT 228
+ E+ R++E+ +E+ + R+ E+ RE+E K ++ + R+ E+ E E E KRQ
Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474
Query: 229 DRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ 288
E RQ + E+E+ ++ + E+ +++E + R ++ R Q+E+ R+ + K
Sbjct: 475 QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Query: 289 RRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQ 348
R+ E+ RE E E RE E+ E+ + E E+ +E+E + R+ E+ RE+E + R+ +
Sbjct: 535 RQEEKIREQE---EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591
Query: 349 TEMDRERNRQTGREGRRQAE---RERERERERDRQSAREREERERDRDRDRQKERERQTE 405
++E RQ E + E RE+E + + + RE+EE+ R+++ Q++ E+ E
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651
Query: 406 KDRDGQRETEKQREREKD--RESERGRERGREREKQKGRERDRERQTDRQ 453
++ + EK +E+E+ R+ E+ RE+ ++ +Q+ + R++E Q
Sbjct: 652 QEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ 701
Score = 156 bits (394), Expect = 6e-38
Identities = 108/415 (26%), Positives = 227/415 (54%), Gaps = 27/415 (6%)
Query: 57 NRQKERERRREKRQTER--ETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
NR +++ + RQ E+ E + K + + EK R Q ++ +E+E + R+ +
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE---------QEEKIREQEEKMRRQEE 342
Query: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
EKE +++ E E+E + R + ++E + +R E E++ E+ R+ E
Sbjct: 343 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE---EKIRELEEK 399
Query: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
++ + + ++R+E E+ RE+E K +++ ++ R+ E+ RE E E+ R+ +++ R
Sbjct: 400 MHEQEKIREQEEKRQEEEKIREQE-KRQEQEAKMWRQEEKIREQE---EKIREQEKKMWR 455
Query: 235 QRKTEREREKQAERERASERETE-RDKERERERD---RDRDRDRRQKERERQTDRKRQRR 290
Q + E+EK E E+ E+E R +E+ E++ R +++ Q+E+ R+ + K R+
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ 515
Query: 291 TERDRETERK-RERQRERERERERNRKRERE-RERERERERQRETERDREKERERKRKRQ 348
E+ RE E K RE++ + R+ E+ R++E RE E+ E+++ E ++ +E+E K RQ
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ 575
Query: 349 TEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERER-QTEKD 407
E RE+ + R+ + E+E +R+ + ++ +E + RE++ Q+E+ R Q EK
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
Query: 408 RDGQRETEKQREREKDRESE--RGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
R+ + T++Q E+ ++E + E+ +E+E+ R+ ++ R+ +++ Q ++
Sbjct: 636 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK 690
Score = 149 bits (376), Expect = 7e-36
Identities = 98/424 (23%), Positives = 233/424 (54%), Gaps = 23/424 (5%)
Query: 58 RQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR 117
+Q + E ++ + + + + + E + + ++ +E + R++E+ ++ + + Q
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Query: 118 EKERNRQ---KERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
EK R ++ +E+E + R+ E +++ +R+ E + E++ RQ + +++ +
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 380
Query: 175 RQKER--EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
RQ+E E+E+ +E E+ ++EK + E++ E + RE+E+ E E + RQ ++ R
Sbjct: 381 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 440
Query: 233 DRQRKT-EREREKQAERERASERETERDKERERERD---RDRDRDRRQKERERQTDRKRQ 288
+++ K E+E++ + E+ E+E R++E+ +E++ R ++ Q+E RQ ++ +
Sbjct: 441 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE 500
Query: 289 RRTERDRETERKRERQRERERERERNRKRERE---RERERERERQ---RETERDREKER- 341
+ E+ R+ E K RQ E+ RE+E + + E R+ E+ RE++ RE E+ E+E+
Sbjct: 501 QE-EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559
Query: 342 ---ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK 398
E++++++ +M R+ + +E + + E+ RE+E RQ E+ ++ ++ R++++
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 399 ERERQTEKDRDGQRETEKQREREKDRESERGRERGR---EREKQKGRERDRERQTDRQAG 455
+ + Q EK R+ + + +Q E +++E + G + + + EK + +E RQ ++
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679
Query: 456 RQRK 459
+++K
Sbjct: 680 QEKK 683
Score = 144 bits (364), Expect = 2e-34
Identities = 97/371 (26%), Positives = 200/371 (53%), Gaps = 25/371 (6%)
Query: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRD---REKERERQTDR 111
E+ ++E+ R +E+++ E E R++E+R+E++ R + R+++ RE+E++
Sbjct: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457
Query: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
E+ ++EK R +K +E+E E Q + R++E+ + E E+ R+ + + RQ
Sbjct: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE-EKIRKQEEKVWRQE 516
Query: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
E+ R++E EK R++ + RQ EK + E+ E + E+E+ E E KRQ
Sbjct: 517 EKIREQE---EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE---EEKRQ---- 566
Query: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
+++ K R+ EK E+E R+ E+ +E+E +R ++ +Q+E+ R+ + K Q +
Sbjct: 567 -EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625
Query: 292 ERDRETERKRERQRERERERERNRKRERERERERERERQRETE---RDREKERERKRKRQ 348
E+ RE E K Q E +E+E + E+ E+E + Q + E R EK RE+++K +
Sbjct: 626 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIR 685
Query: 349 TEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDR 408
+ ++ R ++ + +E+E + + E+EE+ ++++ +++ E+ E++
Sbjct: 686 EQEEKIREQE-------EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 409 DGQRETEKQRE 419
+++ EK +E
Sbjct: 739 RLRQQEEKMQE 749
Score = 133 bits (335), Expect = 4e-31
Identities = 112/415 (26%), Positives = 218/415 (52%), Gaps = 36/415 (8%)
Query: 60 KERERRREKRQTERETDRKRERRREKDRHRKRDRHR----ERQRDRE-----KERERQTD 110
KE+ + +++ E+++ + K+ RK +R + ++Q E KE + +
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
Query: 111 RERDRQREKER-NR-QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
+ + + E E NR +++E + R+ E+ ++ + Q + E+ R+ E E+ R+ + + +
Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE-EKIREQEEKMR 338
Query: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK-RQ 227
RQ E E+E + RQE E++ EK + E+ E+ + R+ E E E K R+
Sbjct: 339 RQEEM--MWEKEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 395
Query: 228 TDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKR 287
+ + Q K + EK+ E E+ RE E+ +E+E + R ++ R Q+E+ R+ ++K
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKI--REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 453
Query: 288 QRRTERDRETERKRERQRERERERERNRKRERERERE---RERERQRETERDREKERERK 344
R+ E+ E E+ RE ++ +E+E E R+ E+ E+E R++E+ E E ++ +++E K
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQE-EMWRQEEKIHEQEEIWRQKEKMHEQE-EKIRKQEEK 511
Query: 345 RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQT 404
RQ E RE Q E+ RE+E + RQ + RE+ E R+ ++ E+E+
Sbjct: 512 VWRQEEKIRE-----------QEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIW 560
Query: 405 EKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
E+++ ++E + R+ EK RE E + R+ EK + +E R+ Q ++ ++ K
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQE--EKVWRQEEKIREQEEKRQEQEEKMWKQEEK 613
Score = 129 bits (324), Expect = 8e-30
Identities = 101/353 (28%), Positives = 190/353 (53%), Gaps = 41/353 (11%)
Query: 52 DDRERNRQKERERRREKRQTE-----RETDRKRE-----RRREKDRHRKRDRHRERQRDR 101
+ E+ +++E+ R +EKRQ + R+ ++ RE R +EK R+ ++ E+++ R
Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 467
Query: 102 EKERERQTDRERDRQREK-----ERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156
E+E+ RQ E RQ EK E RQKE+ E E E+ R ++ R+ E+ R+ E
Sbjct: 468 EEEK-RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE---EKIRKQEEKVWRQEEKIREQE 523
Query: 157 KERERQTDRERQRQTERNRQKE---REREKNRQERR--ERERQREKENKTEDRHSERGRE 211
E+ R+ + + RQ E+ R++E RE EK ++ + E E+++E+E+K R E+ RE
Sbjct: 524 -EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW-RQEEKIRE 581
Query: 212 RE----RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
+E R+ E E E KRQ +++ K ++ EK E+E + + E+ +E+E +
Sbjct: 582 QEEKVWRQEEKIREQEEKRQ-----EQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER 327
+ + Q+E+ + + K + E+ +E E RQ E+ RE+E+ + + E+ RE+E
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 328 ERQRETERDREKE------RERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
Q + E+ E+E E+ ++++ +M R+ + +E R + + E+ +E
Sbjct: 697 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 84.3 bits (207), Expect = 3e-16
Identities = 71/279 (25%), Positives = 138/279 (49%), Gaps = 18/279 (6%)
Query: 187 ERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA 246
++++ +R E+ K D S E R T T+ E K + + +++ + E E+ +
Sbjct: 187 QKKKADRYIEELTKERDALS-----LELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQ 241
Query: 247 ERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
+ +R+ ER K ++ + D KE + K Q + E + E + +Q+E
Sbjct: 242 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ-SVSAKLQAQVE-ENELWNRLNQQQE 299
Query: 307 RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQ 366
+ R+ + +E E + + + E+ RE E ++ +E+E K +RQ EM E+ + RRQ
Sbjct: 300 EKMWRQEEKIQEWEEKIQEQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKM----RRQ 354
Query: 367 AER--ERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424
E E+E + R + E+EE+ R R + E+E + + + E EK RE+E+ R
Sbjct: 355 EEMMWEKEEKMRRQEEMMWEKEEKMR-RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 413
Query: 425 ESE---RGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
+ E R +E+ +E+E + R+ ++ R+ + + Q K+
Sbjct: 414 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
Score = 54.7 bits (130), Expect = 2e-07
Identities = 32/135 (23%), Positives = 70/135 (51%), Gaps = 3/135 (2%)
Query: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
++E Q++ E+ RE+ + RE + + + EK ++ + ++ +E+E E
Sbjct: 616 EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE 675
Query: 113 RDRQREKERNRQKERERETE---REGERGRDRQTDGQRERERQRDAEKERERQTDRERQR 169
+ R++EK+ Q+E+ RE E +E E Q + E+E + ++E+ R+ + +
Sbjct: 676 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 735
Query: 170 QTERNRQKEREREKN 184
Q R RQ+E + +++
Sbjct: 736 QEVRLRQQEEKMQEH 750
Score = 51.2 bits (121), Expect = 3e-06
Identities = 71/320 (22%), Positives = 128/320 (40%), Gaps = 57/320 (17%)
Query: 196 EKENKTEDRHSERGRERERERETET-------ETERKRQTDRERDRQRKTEREREKQAER 248
E E K +H E R RE E + T +TE + + ++ E E R
Sbjct: 108 EDEQKASHQHQEALR-RELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISR 166
Query: 249 -----ERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRER 303
+ A E E +++ DR + KER+ + + R T D E + K +
Sbjct: 167 LHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALS-LELYRNTITDEELKEKNAK 225
Query: 304 QRER----ERERERNRKRERERERERER------ERQRETERDREKERERKRKRQTEMDR 353
+E+ E E+ + +E +R+ ER ++Q + E D + + + +
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 354 ERNRQTGREGRRQAER---------ERERERERDRQSAREREE--RERDRDRDRQ----- 397
E N R ++Q E+ E E + + + RE+EE RE++ RQ
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
Query: 398 -KERERQTEKDRDGQRETEKQREREKDRESERGRERGRE----------------REKQK 440
KE + + +++ ++E + +R+ E E E R E E++K
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405
Query: 441 GRERDRERQTDRQAGRQRKR 460
RE++ +RQ + + Q KR
Sbjct: 406 IREQEEKRQEEEKIREQEKR 425
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 163 bits (412), Expect = 5e-40
Identities = 79/210 (37%), Positives = 148/210 (70%), Gaps = 6/210 (2%)
Query: 117 REKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ 176
RE+ER + +E + ERE ER ++R+ +R+RER+++ ++ER ++ + +++ ER R+
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
K R REK +E E+E++++KE K R S+ G+ERER+ E + E ERK + ++ +R++
Sbjct: 99 KRR-REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE-ERKERERKKEEREK 156
Query: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE 296
+ ER+ K+ ER++ E+E ER KE+ER+ + R+R+R+++++ER+ +R+R+ ER ++
Sbjct: 157 ERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
Query: 297 TERKRERQRERE---RERERNRKRERERER 323
ERK+ERQ++R+ RE+ER ++ +ER++
Sbjct: 216 EERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 161 bits (407), Expect = 2e-39
Identities = 92/229 (40%), Positives = 147/229 (64%), Gaps = 24/229 (10%)
Query: 212 RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRD 271
RERERE ET E K++ + ER ++R REREK R+ ER+KER+RER +
Sbjct: 39 REREREIETRKEGKKERESERKKER---REREK---------RKREREKERKRERGKKEK 86
Query: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
+ R+KE + +RK++RR + ++E E K +R+++ ++ER R K +ERER+ ER+R+
Sbjct: 87 KGERKKE---ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
Query: 332 ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERER-ERERDRQSAREREERER 390
KERERK K + E +RER + RE ++ E+E ER E+ER + RER +ER
Sbjct: 144 R------KERERK-KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
Query: 391 DRDRDRQKERERQTEKDRDGQRETEKQREREKD-RESERGRERGREREK 438
++R+R++ RER+ E+ + +R+ E+Q++R+ + RE ERG+ +ER+K
Sbjct: 197 KKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 160 bits (406), Expect = 2e-39
Identities = 86/235 (36%), Positives = 152/235 (64%), Gaps = 30/235 (12%)
Query: 123 RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE 182
R++ERE ET +EG++ +RE ER+++ + +R+ +RE++R+ ER + KE++ E
Sbjct: 39 REREREIETRKEGKK--------ERESERKKERREREKRKREREKERKRERGK-KEKKGE 89
Query: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER 242
+ ++ER ++R+REKENK G E+E+ RK++ +ER R K +ER
Sbjct: 90 RKKEERERKKRRREKENK-------EGEEKEK---------RKKKEKKERGRTSKEGKER 133
Query: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
E++ ER+R +E ER KE ER+++R+R R+K +Q K + R E++R+ +KRE
Sbjct: 134 ERKEERKREERKERERKKE---EREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
Query: 303 RQR-ERERERERNRKRERERERERERERQRETERDREKE-RERKRKRQTEMDRER 355
R R ER++ERER +RER++ER+++ ER++E ++DR+ RE++R ++ +R++
Sbjct: 191 RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 154 bits (389), Expect = 2e-37
Identities = 76/217 (35%), Positives = 148/217 (68%), Gaps = 11/217 (5%)
Query: 161 RQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETET 220
R+ +RE + + E +++E ER+K R+ER +R+R+REKE K E E+ ER++E E
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKE---ER 95
Query: 221 ETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERE 280
E +++R+ ++ + K +R+++++ ER R S+ ER+++ ER+R+ ++R+R+++ERE
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
Query: 281 RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER-ERERERERQRETERDREK 339
++ +RK +++ ER + E++ ER +E+ER+ +KRER R ER++ERER+ RE+
Sbjct: 156 KERERKERKKRERKQVGEKEEER---KEKERKERKKRERNRKERKKERERKER----RER 208
Query: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376
++ERK+K + + +R+++RQT + + +RER+ ++
Sbjct: 209 KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 152 bits (384), Expect = 8e-37
Identities = 90/210 (42%), Positives = 140/210 (66%), Gaps = 16/210 (7%)
Query: 210 RERERERETETETERKRQTDRERDRQR--KTEREREKQAERERASERETERDKERERERD 267
RERERE ET E +++R+++R+++R+ K +REREK+ +RER + + K+ ERER
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 268 RDRDRDRRQKERERQTDRKRQRRTERDR------ETERKRERQRERERERERNRKRERER 321
+ R R++ KE E + RK++ + ER R E ERK ER+RE +ERER +K ERE+
Sbjct: 99 KRR-REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER-KKEEREK 156
Query: 322 ERERERERQRETERDREKERERKRK-RQTEMDRERNRQTGREGRRQAERERERERERDRQ 380
ERER+ ++RE ++ EKE ERK K R+ RERNR +E +++ ER+ RER+++R+
Sbjct: 157 ERERKERKKRERKQVGEKEEERKEKERKERKKRERNR---KERKKERERKERRERKKERK 213
Query: 381 SARER-EERERDRDRD-RQKERERQTEKDR 408
ER +ER++DR + R+KER ++ K+R
Sbjct: 214 KKEERKKERQKDRQTNWREKERGKRERKER 243
Score = 152 bits (383), Expect = 1e-36
Identities = 77/225 (34%), Positives = 143/225 (63%), Gaps = 18/225 (8%)
Query: 67 EKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKE 126
E R+ ERE + ++E ++E++ RK++R +R RE+E+ER+ RER ++ +K +++E
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERK--RERGKKEKKGERKKEE 94
Query: 127 RERETEREGERGRDRQTDGQRERERQRDAEKE-RERQTDRERQRQTERNRQKEREREKNR 185
RER+ R RE+E + EKE R+++ +ER R ++ +++ER+ E+ R
Sbjct: 95 RERKKRR-------------REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR 141
Query: 186 QERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ 245
+ER+ERER++E+ K +R + ++RER++ E E ERK + +ER ++ + +ER+K+
Sbjct: 142 EERKERERKKEEREK--ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE 199
Query: 246 AERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
ER+ ER+ ER K+ ER+++R +DR +E+ER +++R+
Sbjct: 200 RERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 152 bits (383), Expect = 1e-36
Identities = 89/219 (40%), Positives = 149/219 (68%), Gaps = 18/219 (8%)
Query: 56 RNRQKERERRREKRQTERETDRKRERR-REKDRHRKRDRHRERQRDREKERERQTDRERD 114
R R++E E R+E ++ ERE++RK+ERR REK RKR+R +ER+R+R K +E++ +R+++
Sbjct: 39 REREREIETRKEGKK-ERESERKKERREREK---RKREREKERKRERGK-KEKKGERKKE 93
Query: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
+ K+R R+KE +EGE R+ ++ER R KERER+ +R+R+ + ER
Sbjct: 94 ERERKKRRREKE-----NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148
Query: 175 RQK-EREREKNRQERRERER----QREKENKTEDRHSERGRERERERETETETERKRQTD 229
R+K ERE+E+ R+ER++RER ++E+E K ++R + RER R +E + E ERK + +
Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR-KERKKERERKERRE 207
Query: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDR 268
R+++R++K ER++E+Q +R+ + RE ER K +ER +
Sbjct: 208 RKKERKKKEERKKERQKDRQ-TNWREKERGKRERKERKK 245
Score = 152 bits (383), Expect = 1e-36
Identities = 87/224 (38%), Positives = 143/224 (63%), Gaps = 17/224 (7%)
Query: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
RERE+ + R+E +++RE E K E R E+ R+RE E E +R+R ++ ++K
Sbjct: 39 REREREIETRKEGKKERESERKKERREREK-----RKREREKERKRERGKKEKKGERKKE 93
Query: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
ERER+K+ RE+ ++ E++K +++E+ + KERER+ +RKR+ R ER+R+ E
Sbjct: 94 ERERKKR-RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
+RE+ERER+ +KRER++ E+E ER +E ER K+RER RK E +ER R+
Sbjct: 153 -----EREKERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRK---ERKKERERK 203
Query: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERER 402
RE R+ ER+++ ER+++RQ R+ RE++R + +KER++
Sbjct: 204 ERRE--RKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 148 bits (374), Expect = 1e-35
Identities = 72/201 (35%), Positives = 144/201 (71%), Gaps = 11/201 (5%)
Query: 262 RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER 321
RERER+ + R++ ++ER+++RK++RR ER++ RKRER++ER+RER + K+ +
Sbjct: 39 REREREIET---RKEGKKERESERKKERR-EREK---RKREREKERKRERGKKEKKGERK 91
Query: 322 ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQS 381
+ ERER+++R + ++E E + KRK++ + +R R + G+E R+ ER+RE +ER+
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE--- 148
Query: 382 AREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441
R++EERE++R+R +K+RER+ +++ +R+ ++++ER+K + + R++ RER++++
Sbjct: 149 -RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207
Query: 442 RERDRERQTDRQAGRQRKRST 462
R+++R+++ +R+ RQ+ R T
Sbjct: 208 RKKERKKKEERKKERQKDRQT 228
Score = 147 bits (370), Expect = 4e-35
Identities = 75/215 (34%), Positives = 144/215 (66%), Gaps = 11/215 (5%)
Query: 191 RERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERER 250
RER+RE E + E + ER ER++ER + +R+R+ +R+R+R +K ++ K+ ERER
Sbjct: 39 REREREIETRKEGK-KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERER 97
Query: 251 ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERE 310
R RE+E ++++R+K+ +++ R + ER+R+ ERKRE ++ERER+
Sbjct: 98 KKRR-------REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
Query: 311 RERNRKRERERERERERERQRETERDRE-KERERKRKRQTEMDR-ERNRQTGREGRRQAE 368
+E R++ERER+ ++RER++ E++ E KE+ERK +++ E +R ER ++ R+ RR+ +
Sbjct: 151 KEE-REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
Query: 369 RERERERERDRQSAREREERERDRDRDRQKERERQ 403
+ER+++ ER ++ ++R+ R+++R +++ +ER+
Sbjct: 210 KERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 143 bits (361), Expect = 4e-34
Identities = 77/234 (32%), Positives = 144/234 (61%), Gaps = 37/234 (15%)
Query: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER---QTDRK 286
RER+R+ +T +E +K+ E ER ER ++RERE++R R+R +++K+ ER + +RK
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 287 RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK 346
++RR + ++E E K +R+++ ++ER R K +ERER+ ER+R+ KERERK++
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER------KERERKKE 152
Query: 347 RQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK 406
ERE+ERER +ER++RER + ++++ER+ + K
Sbjct: 153 ---------------------EREKERER-------KERKKRERKQVGEKEEERKEKERK 184
Query: 407 DRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
+R + K+R++E++R+ R R++ R++++++ +ER ++RQT+ + + KR
Sbjct: 185 ERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKR 238
Score = 143 bits (360), Expect = 5e-34
Identities = 84/220 (38%), Positives = 142/220 (64%), Gaps = 10/220 (4%)
Query: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRER-RREKDRH 88
+PG Q R R + +RE R+KER R REKR+ ERE +RKRER ++EK
Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKER-REREKRKREREKERKRERGKKEKKGE 89
Query: 89 RKRDRHRERQRDREKERERQTDRERDRQREK-ERNRQKERERETEREGERGRDRQTDGQR 147
RK++ ++R REKE + ++E+ +++EK ER R + +E ER+ ER R+ + + +R
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
Query: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207
++E + EKERER+ ++R+R+ +++ER +EK R+ER++RER R++ K +R
Sbjct: 150 KKEER---EKERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRKERKKERERKER 205
Query: 208 RGRERERERETETETERK--RQTD-RERDRQRKTEREREK 244
R R++ER+++ E + ER+ RQT+ RE++R ++ +ER+K
Sbjct: 206 RERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 134 bits (337), Expect = 2e-31
Identities = 65/202 (32%), Positives = 126/202 (62%), Gaps = 10/202 (4%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
+ R+ G +E R + ++ +RE+ R++ER ++ +K + ++E +++RRRE
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103
Query: 85 KD---------RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135
K+ R +K + R R KERER+ +R+R+ ++E+ER +++ERE+E ER+
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER-KKEEREKERERKE 162
Query: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195
+ R+R+ G++E ER+ KER+++ ++R+ ER R++ RER+K R+++ ER+++R
Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKER 222
Query: 196 EKENKTEDRHSERGRERERERE 217
+K+ +T R ERG+ +ER+
Sbjct: 223 QKDRQTNWREKERGKRERKERK 244
Score = 109 bits (272), Expect = 8e-24
Identities = 62/180 (34%), Positives = 115/180 (63%), Gaps = 17/180 (9%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQK---------ERERRREKRQTERETDRK 78
R+R +E R RG + + ++RER +++ E+E+R++K + ER K
Sbjct: 69 RKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSK 128
Query: 79 RERRREKDRHRKRDRHRERQR---DREKERERQTDRERDRQR--EKERNRQKERERETER 133
+ RE+ RKR+ +ER+R +REKERER+ ++R+R++ EKE R KE+ER+ +
Sbjct: 129 EGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEER-KEKERKERK 187
Query: 134 EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
+ ER R ++ +RER+ +R+ +KER+++ +R+++RQ +R + RE+E+ ++ER+ER++
Sbjct: 188 KRERNR-KERKKERERKERRERKKERKKKEERKKERQKDR-QTNWREKERGKRERKERKK 245
Score = 90.9 bits (224), Expect = 3e-18
Identities = 65/216 (30%), Positives = 112/216 (51%), Gaps = 32/216 (14%)
Query: 317 RERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376
RERERE E +E ++E E +R+KER + KR+ E ++ER R+ G++ E++ ER++E
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK-----EKKGERKKE 93
Query: 377 RDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRER 436
RER++R R+++ +E+E++ +K++ K+R R ER R+ R+R
Sbjct: 94 E-----RERKKRRREKENKEGEEKEKRKKKEK-------KERGRTSKEGKERERKEERKR 141
Query: 437 EKQKGRERDR-ERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPE 495
E++K RER + ER+ +R+ ++KR V + + R R R ++ E
Sbjct: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEE------RKEKERKERKKRERNRKE 195
Query: 496 DPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKR 531
K R K R R R++ E R E++
Sbjct: 196 RKKE--------RERKERRERKKERKKKEERKKERQ 223
Score = 56.2 bits (134), Expect = 8e-08
Identities = 49/166 (29%), Positives = 80/166 (48%), Gaps = 23/166 (13%)
Query: 380 QSAREREERERDRDRDRQKERERQTEKDRDGQRETEK-QREREKDRESERG-RERGRERE 437
QS ERE + ++ +KERE + +K+R RE EK +REREK+R+ ERG +E+ ER+
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKER---REREKRKREREKERKRERGKKEKKGERK 91
Query: 438 KQKGRERDRERQTDRQAGRQR-KRSTLYVNPPPRTARSGVV---QSDPNRPTRGIRWKSS 493
K++ + R R+ + + G ++ KR RT++ G + + R R R +
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Query: 494 PEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRR 539
E K R R ++R ++GEK + E R
Sbjct: 152 EEREK--------------ERERKERKKRERKQVGEKEEERKEKER 183
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 162 bits (411), Expect = 6e-40
Identities = 123/456 (26%), Positives = 216/456 (47%), Gaps = 57/456 (12%)
Query: 52 DDRER-NRQKERERRREKRQTERETDRKR---------------ERRREKDRHRKRDRHR 95
D++ER NR++ERER ++ + ++R R R R R RDR R
Sbjct: 295 DEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFR 354
Query: 96 E-------RQRDREKERERQTDRERDRQREK-ERNRQKERERETEREGERG----RDRQT 143
RQ + +R R + ER + +K E N KE +R R ER R+
Sbjct: 355 RSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSE 414
Query: 144 DGQRERERQRDAEKERERQTDRERQRQTER-----NRQKEREREKNRQERRERERQREKE 198
R+ E+++ + + +R+ +R +E+ N+ K+R + K+R + +E+ + +E++
Sbjct: 415 SPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERD 474
Query: 199 NKTEDRHSERGRERERERETETETERKRQTDRE-RDRQRKTEREREKQAERERASERETE 257
+K +R R R + R+ E E+++Q+D + +D++R +E+ KQ E +++E +
Sbjct: 475 SKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLE-SKSNEHDHS 533
Query: 258 RDKERERE-RDRDRDRD---------RRQKERERQTDRKRQRRTE-RDRETERKRERQRE 306
+ KE++R + R R+ D R +ER R DR R+ R+ DR+ R +E R
Sbjct: 534 KSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRY 593
Query: 307 RERE-RERNRKRERERE----RERERERQRETERDREKERERKRKRQTEMDRERNRQTGR 361
RE+E R R R R RER R R ++R+R R ERE + R + R + ++
Sbjct: 594 REQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSH 653
Query: 362 EGRRQAERERERERERDRQSAREREERERDRDRD-----RQKERERQTEKDRDGQRETEK 416
+R + RD S+ E++ DRD+ +Q ++ + + +E EK
Sbjct: 654 RKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEK 713
Query: 417 QRER-EKDRESERGRERGREREKQKGRERDRERQTD 451
R EK+ + +G+E EK K + + TD
Sbjct: 714 IRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTD 749
Score = 148 bits (373), Expect = 2e-35
Identities = 109/481 (22%), Positives = 211/481 (43%), Gaps = 51/481 (10%)
Query: 31 PGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRK 90
P S+ + ++ + + + + + + +E T+ K ++R++K R
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238
Query: 91 RDRHRERQRDREKERERQTDRERDRQREKERNRQKERE-------RETEREGERGRDRQT 143
R +E+++ ++ ++ ++ E + + ++ + E R R+ D +
Sbjct: 239 RKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKE 298
Query: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNR----QERRERERQREKEN 199
RERER+R+ + +R+ R+ +K + R R R R+R R E
Sbjct: 299 RKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSET 358
Query: 200 ----KTEDRHSERGRERERER-----ETETETERKRQTDRERDRQRKTEREREKQAERER 250
+ E + ++R R ER ++E ++ Q R ++RK R R
Sbjct: 359 PPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNR 418
Query: 251 ASERETE------RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
+E+E + KER+ R+ ++D + K ++R + R + E+ + ER +
Sbjct: 419 KNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHN 478
Query: 305 RERERERERNRKRERERERERERERQRETE-RDREKERERKRKRQTE-MDRERNRQTGRE 362
R E+ R R+R + R+ E +E+E+Q +++ +D+E+ R +++ +Q E E + +E
Sbjct: 479 RNEEK-RMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKE 537
Query: 363 GRRQAE---------------RERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
R+A+ R RER R R +R R DRDR R KE R E++
Sbjct: 538 KDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE 597
Query: 408 -------RDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
R +R T R R KDR R R ERE+ + R +D+ R + ++ +++
Sbjct: 598 YRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657
Query: 461 S 461
S
Sbjct: 658 S 658
Score = 147 bits (372), Expect = 2e-35
Identities = 95/407 (23%), Positives = 197/407 (48%), Gaps = 48/407 (11%)
Query: 51 GDDRERNRQKERERRREKRQTERETD---------RKRERRREKDRHRKRDRHRERQRDR 101
GD E N KE +R + + + TD RK E+ ++ H+ + R+ +R+
Sbjct: 383 GDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNS 442
Query: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER 161
EK+ ++ ++ + R + K R++ KE+ + ER+ + R+ E +R R K R+
Sbjct: 443 EKD-DKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN-------EEKRMRSRSKGRDH 494
Query: 162 QTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETE 221
+ +E+++Q++ ++ K++ER +++++ ++ E + + + ++ + +R R + R RE +
Sbjct: 495 ENVKEKEKQSD-SKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDR-RAQSRSRECDIT 552
Query: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER 281
+ R R+R R +R R R R +RD+ R +E R R+++ R++ R
Sbjct: 553 KGKHSYNSRTRERSRSRDRSR-------RVRSRTHDRDRSRSKEYHRYREQEYRRRGR-- 603
Query: 282 QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
R R+RRT R R + R R R R+ +RE + R +++ R +E++ KE
Sbjct: 604 --SRSRERRT----PPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657
Query: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE 401
KR R+ N + RE++ +RD+ + ++ +D + +
Sbjct: 658 SESEKRMYSKSRDHN---------SSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKN 708
Query: 402 RQTEKDRDGQRETEKQREREKDRESERGRERGR--EREKQKGRERDR 446
++ EK R EK+ ++ K +E++ E+ + + E G + D+
Sbjct: 709 KEDEKIRS---SVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDK 752
Score = 145 bits (367), Expect = 8e-35
Identities = 121/511 (23%), Positives = 217/511 (42%), Gaps = 78/511 (15%)
Query: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88
R+ ++ R++ A +++ ++ E Q R E R+ + D
Sbjct: 239 RKHKKEKKKRKKSKKSASSESEAENLEAQPQST-VRPEEIPPIPENRFLMRKSPPKADEK 297
Query: 89 RKRDRHRERQRD----------------------REKERERQTDRERDRQREKERNRQKE 126
+++R RER+R+ + K R + R R R ++R R+ E
Sbjct: 298 ERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSE 357
Query: 127 RERETEREGERG-RDRQTDGQR-----------ERERQRDAEKERERQTDRERQRQTERN 174
+E +R R R + G+R +E QR + +ER+ R N
Sbjct: 358 TPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPN 417
Query: 175 RQKERERE--------KNRQERRERERQREKENKTEDRHSERGRERERERETETE----- 221
R+ E+E++ K R RR E+ + +NK + R + R + +E+ E
Sbjct: 418 RKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKH 477
Query: 222 --TERKRQTDRERDRQRKTEREREKQA-------ERERASERETE-RDKERERERDRDRD 271
E KR R + R + +E+EKQ+ ER R+ E+ + K E + + ++
Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKE 537
Query: 272 RDRRQKERERQTD----------RKRQRRTERDRETE-RKRERQRERERERERNRKRERE 320
+DRR + R R+ D R R+R RDR R R R+R R +E +R RE+E
Sbjct: 538 KDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQE 597
Query: 321 ---RERERERERQRETERDREKERERKRKRQTEMDRE----RNRQTGREGRRQAERERER 373
R R R RER+ R R K+R R+R+ +RE RN+ R ++ +E
Sbjct: 598 YRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657
Query: 374 ERERDRQSAREREERERDRDRDRQKERERQT-EKDRDGQRETEKQREREKDRESERGRER 432
R ++ R+ + R+++ +R++ K + ++ E + K++E E+ R
Sbjct: 658 SESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSS 717
Query: 433 -GREREKQKGRERDRERQTDRQAGRQRKRST 462
+E +K KG+E D + +++ + T
Sbjct: 718 VEKENQKSKGQENDHVHEKNKKFDHESSPGT 748
Score = 120 bits (301), Expect = 4e-27
Identities = 107/482 (22%), Positives = 198/482 (41%), Gaps = 56/482 (11%)
Query: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
+ + ++ EK RH+ D + + Q+ + + K+R+++ +
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS- 238
Query: 137 RGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196
R + + ++ ++ ++ A E E + + + T R + E R+ + E
Sbjct: 239 --RKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADE 296
Query: 197 KENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERET 256
KE K RERERERE + R R + + + R R R
Sbjct: 297 KERKN--------RERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSR 348
Query: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER--- 313
RD+ R E ++ ++ +R R + +R + ++ E K E QR R +ER
Sbjct: 349 SRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIK-ENQRSPVRVKERKIT 407
Query: 314 ---------NRKRERERE------RERERERQRETERD---REKERERKRKRQTEMDRER 355
NRK E+E++ +ER+ +R +E+D + K ++R + + +E+
Sbjct: 408 DHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEK 467
Query: 356 NRQTGRE---GRRQAERERERERERDRQSAREREERE----RDRDRDRQKERERQTEKDR 408
++ R+ R + +R R R + RD ++ +E+E++ +D++R R KE+ +Q E
Sbjct: 468 SKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESK- 526
Query: 409 DGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPP 468
E + + +EKDR R + R RE + KG+ R +R R R
Sbjct: 527 --SNEHDHSKSKEKDR---RAQSRSRECDITKGKHSYNSRTRERSRSRDRS--------- 572
Query: 469 PRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLG 528
R RS D +R R++ + S P SR + RRR + R
Sbjct: 573 -RRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSS 631
Query: 529 EK 530
E+
Sbjct: 632 ER 633
Score = 99.4 bits (246), Expect = 9e-21
Identities = 73/294 (24%), Positives = 135/294 (45%), Gaps = 47/294 (15%)
Query: 27 SRRRPGSQESPRRRGLGQAHK---------DADGDDRERNRQKERERRREKRQTERETDR 77
S+ ++ R R G+ H+ D+ G D+ER+R KE+ ++ E + E +
Sbjct: 475 SKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHD--- 531
Query: 78 KRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGER 137
+ +EKDR R + R R+ D K + R R+R R ++R+R R
Sbjct: 532 -HSKSKEKDR---RAQSRSRECDITKGKHSYNSRTRERSRSRDRSR-------------R 574
Query: 138 GRDRQTDGQRERERQRDAEKERE---RQTDRERQRQTERNRQKEREREKNRQERRERERQ 194
R R D R R ++ +E+E R R R+R+T R + ++R + R++ R ER+
Sbjct: 575 VRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSERE 634
Query: 195 REKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERA--- 251
E +++ +D++ R +E + E KR + RD + REK+A+R+++
Sbjct: 635 -ESQSRNKDKY--RNQESKSSHRKENSESEKRMYSKSRD-HNSSNNSREKKADRDQSPFS 690
Query: 252 --------SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRET 297
+E ++ K +E E+ R QK + ++ D ++ + D E+
Sbjct: 691 KIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHES 744
Score = 81.3 bits (199), Expect = 2e-15
Identities = 51/219 (23%), Positives = 99/219 (45%), Gaps = 8/219 (3%)
Query: 33 SQESPRRRGLGQAHKD-ADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKR 91
S+E RR D G +R +ER R R++ + R R+R R K+ HR R
Sbjct: 535 SKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYR 594
Query: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERER 151
++ R+R R + RER+T R R +++ R R+ R E E R +D+ + + +
Sbjct: 595 EQEY-RRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSH 653
Query: 152 QRDAEKERERQTDRERQRQTERN-RQKERERE-----KNRQERRERERQREKENKTEDRH 205
+++ + +R + R + N R+K+ +R+ K +Q ++ E + ED
Sbjct: 654 RKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEK 713
Query: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREK 244
E+E ++ E + + +++ D + + +K
Sbjct: 714 IRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDK 752
Score = 64.3 bits (155), Expect = 3e-10
Identities = 52/201 (25%), Positives = 84/201 (41%), Gaps = 29/201 (14%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
D SRR R + H+ + + R R R R RERR
Sbjct: 570 DRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRS-----------------RSRERRTP 612
Query: 85 KDRHRKRDRHRERQRDREKERERQTDRERD--RQREKERNRQKERERETEREGERGRD-R 141
R R +DR R R+ R ERE R +D R +E + + +KE +R + RD
Sbjct: 613 PGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHN 672
Query: 142 QTDGQRERERQRDA---EKERERQTDRERQRQTERNRQKER-----EREKNRQERRERER 193
++ RE++ RD K ++ D E + +N++ E+ E+E + + +E +
Sbjct: 673 SSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDH 732
Query: 194 QREKENKTEDRHSERGRERER 214
EK NK D S G + ++
Sbjct: 733 VHEK-NKKFDHESSPGTDEDK 752
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 158 bits (399), Expect = 2e-38
Identities = 85/196 (43%), Positives = 143/196 (72%), Gaps = 15/196 (7%)
Query: 168 QRQTERNRQKEREREKNRQER-RERERQREKENKTEDRHSERGRERERERETETETERKR 226
QR++ER +++ REREK ++ER +ER+R+R K+ K + + ERG+ERER+R+ ER++
Sbjct: 31 QRESERKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRK-----EREK 84
Query: 227 QTDRERDRQRKTEREREKQAERERASERETERDKER-ERERDRDRDRDRRQKERERQTDR 285
Q R+++R+ ++ +K+ ER++ RE ++ KER ERER+ + R+R++K+R R
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR-----R 139
Query: 286 KRQRRTERDRETER-KRERQRERERERERNRKRERER-ERERERERQRETERDREKERER 343
K++RR ER RE ER KRER+R++ ++ ER +KRER R ER++ERER+ ER +E+++ER
Sbjct: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKER 199
Query: 344 KRKRQTEMDRERNRQT 359
++K++ + DR+ +RQT
Sbjct: 200 RKKKERKKDRKTDRQT 215
Score = 155 bits (393), Expect = 8e-38
Identities = 85/215 (39%), Positives = 143/215 (66%), Gaps = 21/215 (9%)
Query: 176 QKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQ 235
Q+E ER+K R+ER +R+R+REKE K E E+ + ++RER E E +RK ER++Q
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRK-----EREKQ 85
Query: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR 295
RK RE+E++ ++ +RE ++ RER++ ++R KERER+ ++R+R+ ++ R
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKER------KERERENKQRRERKRKKRR 139
Query: 296 ETERKRERQRERER-ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
+ +R++ER+RE+ER +RER RK+ ++ ERE++RER R ++R+KERERK + RE
Sbjct: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR---KERKKERERKER------RE 190
Query: 355 RNRQTGREGRRQAERERERERERDRQSAREREERE 389
R ++ +E R++ ER+++R+ +R S R RE
Sbjct: 191 RKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
Score = 155 bits (391), Expect = 1e-37
Identities = 82/197 (41%), Positives = 138/197 (70%), Gaps = 9/197 (4%)
Query: 54 RERNRQKERERRREKRQTERETDRKRER-RREKDRHRKRDRHRERQRDREKERERQTDRE 112
RE R+KER R REKR+ ERE +RKRER ++EK + +KR+R +ER+R R KERE+Q
Sbjct: 32 RESERKKER-REREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQRKER 89
Query: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
R+++R K + +K+RER+ ER + ++ ++ERER+ +ER+R+ R+++R+ E
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKE---RKERERENKQRRERKRKKRRKKKRRKE 146
Query: 173 RNRQKER-EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
R R+KER +RE+ R++R++ ER++++E ++R ER R+ RER+ E + ER+++ +R+
Sbjct: 147 RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
Query: 232 RDRQRKTEREREKQAER 248
+D RKT+R+ + Q R
Sbjct: 207 KD--RKTDRQTDSQVFR 221
Score = 152 bits (384), Expect = 8e-37
Identities = 83/208 (39%), Positives = 149/208 (71%), Gaps = 21/208 (10%)
Query: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
RE ER++E +RKR+ ++ER R+R ++E++K+ +RER ERE +R KERE++R
Sbjct: 32 RESERKKERREREKRKREREKERKRERG-KKEKKKRKKRERGKERERKR-KEREKQRKER 89
Query: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
R+++RR++++E+ +KR+R+ RE ++K+ER +ERERE ++ R+R+R++ R+++R +
Sbjct: 90 REKERRKRKKEK---KKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRRK 145
Query: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERE 389
+R+ E++R K RERKRK++ + +RE+ R+ R +ER++ERER +ER ER+
Sbjct: 146 ERKREKERGK-RERKRKKRKKEEREKKRERNR-------KERKKERER-----KERRERK 192
Query: 390 RDRDRDRQKERERQTEKDRDGQRETEKQ 417
++R ++R+K++ER +KDR R+T+ Q
Sbjct: 193 KERKKERRKKKER--KKDRKTDRQTDSQ 218
Score = 150 bits (380), Expect = 2e-36
Identities = 70/206 (33%), Positives = 144/206 (69%), Gaps = 19/206 (9%)
Query: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER 281
T+R+ + +ER + K +REREK+ +RER +++K++ ++R+R ++R+R++KERE+
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERG-----KKEKKKRKKRERGKERERKRKEREK 84
Query: 282 QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
Q RK +R ER + + K++R+R++ RER +K+ER +ERERE ++ ER R+K R
Sbjct: 85 Q--RKERREKERRKRKKEKKKRERKQRGRRERKKKKER---KERERENKQRRERKRKKRR 139
Query: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE 401
++KR+++ + ++ER ++ ER+R++ ++ +R+ RER +ER ++R+R++ RE
Sbjct: 140 KKKRRKERKREKERGKR---------ERKRKKRKKEEREKKRERNRKERKKERERKERRE 190
Query: 402 RQTEKDRDGQRETEKQREREKDRESE 427
R+ E+ ++ +++ E++++R+ DR+++
Sbjct: 191 RKKERKKERRKKKERKKDRKTDRQTD 216
Score = 150 bits (379), Expect = 3e-36
Identities = 78/205 (38%), Positives = 144/205 (70%), Gaps = 19/205 (9%)
Query: 256 TERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER---ERE 312
T+R+ ER++ER R+R +++RER+ +RKR+R +++++ +KRER +ERER ERE
Sbjct: 30 TQRESERKKER-----REREKRKREREKERKRERG-KKEKKKRKKRERGKERERKRKERE 83
Query: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372
+ RK RE+ER + ++ +++ ER + RERK+K++ + +RER + RE +R+ R+++
Sbjct: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK-ERERENKQRRERKRKKRRKKK 142
Query: 373 RERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER 432
R +ER R+ +ER +RER R + +++ERE++ E++R K+R++E++R+ R R++
Sbjct: 143 RRKERKRE--KERGKRERKRKKRKKEEREKKRERNR-------KERKKERERKERRERKK 193
Query: 433 GREREKQKGRERDRERQTDRQAGRQ 457
R++E++K +ER ++R+TDRQ Q
Sbjct: 194 ERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 148 bits (374), Expect = 1e-35
Identities = 83/234 (35%), Positives = 158/234 (67%), Gaps = 22/234 (9%)
Query: 131 TEREGERGRDRQTDGQRERERQRDAEKER---ERQTDRERQRQTERNRQKEREREKNRQE 187
T+RE ER ++R+ +R+RER+++ ++ER E++ ++R+R ER R K +EREK R+E
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERER-KRKEREKQRKE 88
Query: 188 RRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAE 247
RRE+ER++ K+ K + +RGR RER++ +K + +RER+ +++ ER+R+K+
Sbjct: 89 RREKERRKRKKEKKKRERKQRGR-RERKK-------KKERKERERENKQRRERKRKKR-- 138
Query: 248 RERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER 307
R+ +R KER+RE++R + R+R++K+R+++ K++ R ++R+ ER+R+ +RER
Sbjct: 139 ------RKKKRRKERKREKERGK-RERKRKKRKKEEREKKRERNRKERKKERERKERRER 191
Query: 308 ERERERNRKRERERERERERERQRETERDRE-KERERKRKRQTEMDRERNRQTG 360
++ER++ R++++ER+++R+ +RQ +++ R +E R T + R R TG
Sbjct: 192 KKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYRIFHTG 245
Score = 148 bits (374), Expect = 1e-35
Identities = 75/206 (36%), Positives = 139/206 (67%), Gaps = 23/206 (11%)
Query: 109 TDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
T RE +R++E+ +++RERE ER+ ERG+ KE++++ RER
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGK-----------------KEKKKRKKRERG 72
Query: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG-RERERERE-TETETERKR 226
++ ER K +EREK R+ERRE+ER++ K+ K + +RG RER++++E E E E K+
Sbjct: 73 KERER---KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129
Query: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
+ +R+R ++RK +R +E++ E+ER +RE +R K ++ ER++ R+R+R+++++ER+ +
Sbjct: 130 RRERKRKKRRKKKRRKERKREKER-GKRERKRKKRKKEEREKKRERNRKERKKERERKER 188
Query: 287 RQRRTERDRETERKRERQRERERERE 312
R+R+ ER +E +K+ER+++R+ +R+
Sbjct: 189 RERKKERKKERRKKKERKKDRKTDRQ 214
Score = 146 bits (369), Expect = 5e-35
Identities = 71/213 (33%), Positives = 146/213 (68%), Gaps = 10/213 (4%)
Query: 71 TERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERE 130
T+RE++RK+ERR + R R+R++ R+R+R + KE++++ RER ++RE++R KERE++
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKR---KEREKQ 85
Query: 131 TEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRE 190
+ E+ R ++ +++RER++ +ER+++ +R ++R+ E +++ER+R+K R+++R
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRR 144
Query: 191 RERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERER 250
+ER+REKE +R ++ ++ ERE++ E + + +R+++R+RK RER+K+ ++ER
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREKKRE-----RNRKERKKERERKERRERKKERKKER 199
Query: 251 ASERETERDKERERERDRDRDRDRRQKERERQT 283
++E ++D++ +R+ D R R+ R T
Sbjct: 200 RKKKERKKDRKTDRQTDSQVFRPLRESAFNRVT 232
Score = 143 bits (360), Expect = 5e-34
Identities = 79/214 (36%), Positives = 147/214 (68%), Gaps = 27/214 (12%)
Query: 96 ERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDA 155
+R+ +R+KER + R+R+R++E++R R K +E++ ++ ERG +ERER+R
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGK-KEKKKRKKRERG--------KERERKR-- 79
Query: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE 215
KERE+Q R+ +R+ ER ++K+ ++++ R++R RER+++KE K ERERE
Sbjct: 80 -KEREKQ--RKERREKERRKRKKEKKKRERKQRGRRERKKKKERK----------ERERE 126
Query: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER-DRDRDRDR 274
+ E +RK++ ++R ++RK E+ER K+ ER+R ++ ER+K+RER R +R ++R+R
Sbjct: 127 NKQRRERKRKKRRKKKRRKERKREKERGKR-ERKRKKRKKEEREKKRERNRKERKKERER 185
Query: 275 RQKERERQTDRKRQRRTERDRETERKRERQRERE 308
+++ RER+ +RK++RR +++R+ +RK +RQ + +
Sbjct: 186 KER-RERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 142 bits (358), Expect = 9e-34
Identities = 74/183 (40%), Positives = 135/183 (73%), Gaps = 8/183 (4%)
Query: 280 ERQTDRKRQRRTERDRETERKRERQRER-ERERERNRKRERERERERERERQRETERDRE 338
+R+++RK++RR R+ ER++ER+RER ++E+++ +KRER +ERER+R ++RE +R
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQRKER 89
Query: 339 KERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK 398
+E+ER+++++ + RER ++ RE +++ ER +ERER+ + RER+ ++R R + R+K
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKER---KERERENKQRRERKRKKR-RKKKRRK 145
Query: 399 ERERQTEK-DRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457
ER+R+ E+ R+ +R+ K+ EREK RE R +ER +ERE+++ RER +ER+ +R+ ++
Sbjct: 146 ERKREKERGKRERKRKKRKKEEREKKRERNR-KERKKERERKERRERKKERKKERRKKKE 204
Query: 458 RKR 460
RK+
Sbjct: 205 RKK 207
Score = 132 bits (333), Expect = 7e-31
Identities = 70/197 (35%), Positives = 133/197 (67%), Gaps = 21/197 (10%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
R+R +E R RG + K ++R R KERER+R++R+ +R+ R++ERR+ K
Sbjct: 46 RKREREKERKRERGKKEKKKR-----KKRERGKERERKRKEREKQRKERREKERRKRKKE 100
Query: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
+KR+R + +R+R+K++ER+ +RER+ ++ +ER R+K R+++ +E +R ++R G+R
Sbjct: 101 KKKRERKQRGRRERKKKKERK-ERERENKQRRERKRKKRRKKKRRKERKREKER---GKR 156
Query: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207
ER+R++ ++ERE++ +R R KER++E+ R+ERRER+++R+KE + + E
Sbjct: 157 ERKRKKRKKEEREKKRERNR---------KERKKERERKERRERKKERKKERR---KKKE 204
Query: 208 RGRERERERETETETER 224
R ++R+ +R+T+++ R
Sbjct: 205 RKKDRKTDRQTDSQVFR 221
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 149 bits (377), Expect = 5e-36
Identities = 113/446 (25%), Positives = 210/446 (47%), Gaps = 23/446 (5%)
Query: 33 SQESPRRRGLGQAHKDADGDDRERNRQKER-ERRREKRQTERETDRKRERRREKDRHRKR 91
+++ P RG G + + G + ++ ++E+ E+ + + + ER + ++E EK+ +KR
Sbjct: 647 AEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELA-EKEEWKKR 705
Query: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKE----RERETEREGE---RGRDRQTD 144
D + Q++RE+ +++ ++E + E+E +E RE E E+EGE G + +
Sbjct: 706 DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVE 765
Query: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN-KTED 203
G+RE+E + E+++E + +E + + E + Q E E E+ E+E E E + E+
Sbjct: 766 GEREKE---EGERKKEERAGKEEKGEEEGD-QGEGEEEETEGRGEEKEEGGEVEGGEVEE 821
Query: 204 RHSERGRERERER--ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKE 261
ER E E E E E E + E + + K E E E+ E E E E ++E
Sbjct: 822 GKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEE 881
Query: 262 R-ERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
E E + + + + ++E E + + + + E + + E E E E E
Sbjct: 882 EGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEG 941
Query: 321 RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQ 380
+ E E E + E+E E + + + E + E G E + E E E E +
Sbjct: 942 EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001
Query: 381 SAREREERERDRDRDRQKERERQTEKDR---DGQRET--EKQREREKDRESERGRERGRE 435
EE E + + + + E E + E + +G+ E E+ EREK+ E E R E
Sbjct: 1002 EGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREE 1061
Query: 436 REKQKGRERDR-ERQTDRQAGRQRKR 460
E+++G+ ++ E + +RQ G + K+
Sbjct: 1062 EEEEEGKYQETGEEENERQDGEEYKK 1087
Score = 139 bits (351), Expect = 6e-33
Identities = 110/414 (26%), Positives = 183/414 (44%), Gaps = 17/414 (4%)
Query: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHR 89
RPG E + + K DG+++E QKERE+ +K + + E + E +
Sbjct: 688 RPG--EGEKELAEKEEWKKRDGEEQE---QKEREQGHQKERNQ-EMEEGGEEEHGEGEEE 741
Query: 90 KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRER 149
+ DR E +++ E + E + + E + +REKE +K+ ER + E+G + G+ E
Sbjct: 742 EGDREEEEEKEGEGKEEGEGE-EVEGEREKEEGERKKEERAGKE--EKGEEEGDQGEGEE 798
Query: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209
E +E+E + E E ++E E E+ E E E + E+ E+ +G
Sbjct: 799 EETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKG 858
Query: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
E E E E E E E + + + E E E + E E E E E ++E E E + +
Sbjct: 859 EEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE---EGEGEGEEEGEGEGEEE 915
Query: 270 RDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
+ ++E E + E + E + E E E E + E E E E E E
Sbjct: 916 EGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGE---EEEGEGEGEEEGEG 972
Query: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERE 389
+ E +E E + + + E E + G EG + E E E E E + + E EE E
Sbjct: 973 EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEG-EGEEEGEGEGEEEEEGEVEGEVEGEEGE 1031
Query: 390 RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRE 443
+ + + +E + EK+ +G+ E + RE E++ E + E E+Q G E
Sbjct: 1032 GEGEEEEGEEEGEEREKEGEGE-ENRRNREEEEEEEGKYQETGEEENERQDGEE 1084
Score = 120 bits (301), Expect = 4e-27
Identities = 108/447 (24%), Positives = 193/447 (43%), Gaps = 34/447 (7%)
Query: 28 RRRPGSQESPRRRGLGQAHKD----ADGDDRERNRQKERERRREKRQTERETDRKRERRR 83
++R G ++ + R G + +G + E +E E RE+ + E+E + K E
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEE-EKEGEGKEEGEG 761
Query: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDR---QREKERNRQKERERETEREGERGRD 140
E+ + ER+++ +E + + E D+ + E+ R +E+E E EG G
Sbjct: 762 EEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEG--GEV 819
Query: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
+ G+RE E + +E E + + E E + + E E E E + E E +
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGE 879
Query: 201 TEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDK 260
E+ E E E E E E + + + E + + + E E + E E E E ++
Sbjct: 880 EEEGEGEGEEEGEGEGE-----EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Query: 261 ERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
E D + + ++E E + + + + E + E E + E + E E E E E
Sbjct: 935 EEGEGEGEDGEGEGEEEEGEWEGE-EEEGEGEGEEEGEGEGE-EGEGEGEEEEGEGEGEE 992
Query: 321 RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQ 380
E E E E + E E + E E E + + + E + E G EG + E E E +R+
Sbjct: 993 EEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVE-----GEEGEGEGEEEEGEEEGEERE 1047
Query: 381 SAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ--REREKDRESERGRERGREREK 438
E EE R+R+ + ++E + Q G+ E E+Q E +K + + + G+ +
Sbjct: 1048 KEGEGEENRRNREEEEEEEGKYQ----ETGEEENERQDGEEYKKVSKIKGSVKYGKHKTY 1103
Query: 439 QKGRERDRERQTDRQAGRQRKRSTLYV 465
QK + T+ Q + +RS + V
Sbjct: 1104 QK------KSVTNTQGNGKEQRSKMPV 1124
Score = 114 bits (285), Expect = 3e-25
Identities = 94/374 (25%), Positives = 166/374 (44%), Gaps = 23/374 (6%)
Query: 101 REKERERQTDRERDRQREKERNRQKERERE---------TEREGERGRDRQTDGQRERER 151
R+++ E +D D+ E + E E T EG G + D +RE+
Sbjct: 619 RKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGE 678
Query: 152 QRDAEKERERQTDRERQ---RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
+ E ER + E++ ++ + R E + +K R++ ++ER +E E E+ H E
Sbjct: 679 KDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE- 737
Query: 209 GRERERERETETETERKRQTDRERDRQRKTEREREK-QAERERASERETERDKERERERD 267
G E E +RE E E E + + + E + + + ERE+E+ + ++E + +E + ++E ++
Sbjct: 738 GEEEEGDREEEEEKEGEGKEEGEGE-EVEGEREKEEGERKKEERAGKEEKGEEEGDQGEG 796
Query: 268 RDRDRDRRQKERER----QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE- 322
+ + + R +E+E + + + ER+ E E + E E E E E E E
Sbjct: 797 EEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEG 856
Query: 323 -RERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQS 381
E E E E E E E + + E G E + E E E E E + +
Sbjct: 857 KGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Query: 382 AREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441
+ E E + +E E + E + DG+ E E++ E E + E E G G E + +G
Sbjct: 917 GEGKGEEEGEEGEGEGEEEEGEGEGE-DGEGEGEEE-EGEWEGEEEEGEGEGEEEGEGEG 974
Query: 442 RERDRERQTDRQAG 455
E + E + + G
Sbjct: 975 EEGEGEGEEEEGEG 988
Score = 78.2 bits (191), Expect = 2e-14
Identities = 76/350 (21%), Positives = 146/350 (41%), Gaps = 31/350 (8%)
Query: 124 QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREK 183
QK+++++T GE +D + + + + +E + ++ Q Q E
Sbjct: 521 QKQKKQQTI--GELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEA 578
Query: 184 NRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERERE 243
E E ++E ++ E E + RK +T+ D T++
Sbjct: 579 FSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDL--TDKAEV 636
Query: 244 KQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRER 303
+ + + E E + + + ++ ER+ K + R E +R E ++E
Sbjct: 637 SEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKEL 696
Query: 304 QRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363
E+E +KR+ E + ++ERE+ + ER++E E + E EG
Sbjct: 697 A-----EKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG--------EEEHGEGEEEEG 743
Query: 364 RRQAERERERERERDR-----QSAREREERERDRDRDRQKERERQTEKDR-DGQRETEKQ 417
R+ E E+E E + + + RE+EE ER ++ KE + + E D+ +G+ E +
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG 803
Query: 418 REREKDR-------ESERGR-ERGREREKQKGRERDRERQTDRQAGRQRK 459
R EK+ E E G+ ER E E+ +G E + E + + G + +
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE 853
Score = 65.5 bits (158), Expect = 1e-10
Identities = 83/386 (21%), Positives = 141/386 (36%), Gaps = 44/386 (11%)
Query: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERET-----E 219
+++++QT ++ +N E KE K +H +G + T +
Sbjct: 522 KQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSD 581
Query: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKER---ERERDRDRDRDRRQ 276
E E + + D + E+E +A E ++K + D+ + +
Sbjct: 582 EEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKA 641
Query: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD 336
K D R E E ++ ERE+ K E ER E E++
Sbjct: 642 KSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELA---- 697
Query: 337 REKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396
E+E +KR E ++ R+ G + R E E E E E EE E DR+ +
Sbjct: 698 ---EKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHG-----EGEEEEGDREEEE 749
Query: 397 QKERERQTEKDRDGQRETEKQRERE-KDRESERGRERG-REREKQKGRERDRERQTDRQA 454
+KE E + E E ++ E ER +E G R++E++ G+E E + D+
Sbjct: 750 EKEGEG--------------KEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGE 795
Query: 455 GRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPE---DPKAASTRFPWGRPAK 511
G + + G V+ +G R + E + + G +
Sbjct: 796 GEEEETE----GRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE-GE 850
Query: 512 ASRGRVAGRRRWEPRLGEKRGQGGEG 537
G G E GE+ G+ GEG
Sbjct: 851 EEEGEGKGEEEGEEGEGEEEGEEGEG 876
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 148 bits (374), Expect = 1e-35
Identities = 99/391 (25%), Positives = 201/391 (51%), Gaps = 24/391 (6%)
Query: 57 NRQKERERRREKRQTER--ETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
NR +++ + RQ E+ E + K + + EK R Q ++ +E+E + R+ +
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE---------QEEKIREQEEKMRRQEE 342
Query: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
EKE +++ E E+E + R + ++E E+ R+ E++ Q Q + +
Sbjct: 343 MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE-EKIRELEEKMHEQEKIREQEEKRQE 401
Query: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
+K RE+EK +++ + RQ EK + E++ E+ ++ R+ E E E+ R+ + +R
Sbjct: 402 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE-EEKRQE 460
Query: 235 QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294
Q + R+ EK E+E + R++E+ ++++ R+Q+E+ + + K + E+
Sbjct: 461 QEEMWRQEEKIREQE---------EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKI 511
Query: 295 RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
RE E K RQ E+ RE+E + + E+ RE+E Q + E+ E+E + + + + E
Sbjct: 512 REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEE 571
Query: 355 RNRQTGREGRRQAERERERERE--RDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
+ R+ + R Q E+ RE+E + + RE+EE ++++ ++ E+ E++ Q
Sbjct: 572 KIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 631
Query: 413 ETEKQREREKDRESERGRERGREREKQKGRE 443
+ EK R +E+ + R R +E + Q+ +E
Sbjct: 632 QEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 143 bits (361), Expect = 4e-34
Identities = 97/358 (27%), Positives = 197/358 (55%), Gaps = 13/358 (3%)
Query: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
E Q++ E+ RE+ + RE + K R+ E ++ R+ + EKE + + E
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
Query: 115 RQREKERNRQKERERETEREGERGRDRQTDGQ-RERERQRDAEKERERQTDRERQRQTER 173
++E++ +E+ E E+ E+ RQ + + RE+E++++ E + RQ ++ R+ Q E+
Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE-QEEK 431
Query: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
R++E++ + ++ E+E+ RE+E + E R E+ RE+E E R+++ E++
Sbjct: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE---EIWRQKEKMHEQE 488
Query: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
+ RK E + +Q E+ E E+ +E+E + R ++ R Q+E+ R+ + K + + E
Sbjct: 489 KIRKQEEKVWRQEEKMHDQE---EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545
Query: 294 DRETERKRERQRERERERERNRKRERE-RERERERERQRETERDREK---ERERKRKRQT 349
+E E K Q E+ +E+E+ R++E + RE+E + Q+E R++E+ E+E K + Q
Sbjct: 546 MQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQE 605
Query: 350 EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
EM +E+ + + + E+E E+ +E++ + R+ E+ R RQ+E + Q ++
Sbjct: 606 EMMQEQEEKMWEQEEKMCEQE-EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 141 bits (355), Expect = 2e-33
Identities = 107/437 (24%), Positives = 236/437 (54%), Gaps = 38/437 (8%)
Query: 50 DGDDRERNRQ-KERERRREKRQTE-----RETDRKRERRR----------EKDRHRKRDR 93
D + +E+N + +E+ + E ++E +E RK ER + E D H ++
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD-HLGKEL 274
Query: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
+ + + E + ++Q+E++ RQ+E+ +E E E+ ++++ + + E+ R
Sbjct: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE---EKIQEQEEKIREQEEKIR 331
Query: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKT---EDRHSERGR 210
+ E++ RQ + +++ + RQ+E EK + RR E EKE K E++ E+ +
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391
Query: 211 ERERERETETETERKRQTDRERDRQRKTEREREK---QAERERASERETERDKERERERD 267
RE+E E E E+ R+ ++ ++++ K R+ EK Q E+ R E++ R +E+ E++
Sbjct: 392 IREQE-EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 450
Query: 268 RDRDRDRRQKERE--RQTDRKRQ-----RRTERDRETERKRERQRERERERER-NRKRER 319
+ R+ ++RQ++ E RQ ++ R+ R+ E+ E E+ R+++ + R+ E+ + + E+
Sbjct: 451 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK 510
Query: 320 ERERERERERQRETERDRE---KERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376
RE+E + RQ E R++E +E+E K + Q EM +E+ + G + + E+E+ R +E
Sbjct: 511 IREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE 570
Query: 377 RDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRER 436
+ E+ ++++ R+++++ Q EK R+ + ++Q E+ ++E + + + +
Sbjct: 571 EKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 630
Query: 437 EKQKGRERDRERQTDRQ 453
E+++ R E+ +++
Sbjct: 631 EQEEKMRRQEEKMWEQE 647
Score = 136 bits (342), Expect = 6e-32
Identities = 105/410 (25%), Positives = 209/410 (50%), Gaps = 24/410 (5%)
Query: 63 ERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERN 122
E +EK +E + E + + + ++ R+ +R + ++Q E D ++ ++
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 123 RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE 182
+ + + E R Q Q+E + R EK +E + + Q + R Q+E+ RE
Sbjct: 277 VSAKLQAQVEENELWNRLNQ---QQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIRE 332
Query: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETET----ETERKRQTDRERDRQRKT 238
+ + RR+ E EKE K + + E+ R E + E+ R+ + + Q K
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 392
Query: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
+ EK+ E E+ RE E+ +E+E + R ++ R Q+E+ R+ ++K R+ E+ E E
Sbjct: 393 REQEEKRQEEEKI--REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 450
Query: 299 RKRERQRERERERERNRKRERERERE---RERERQRETERDREKERERKRKRQTEMDRER 355
+ RE ++ +E+E E R+ E+ RE+E R++E+ E E+ R++E + R+ + D+E
Sbjct: 451 KIREEEKRQEQE-EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE 509
Query: 356 N-RQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRET 414
R+ + RQ E+ RE+E + RE+EE+ R+++ Q++ E+ E++ Q +
Sbjct: 510 KIREQEEKMWRQEEKIREQE-----EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
Query: 415 EKQREREKDRESE----RGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
+ +R+ EK RE E +E+ RE+E++ + ++ R+ + Q ++
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614
Score = 135 bits (339), Expect = 1e-31
Identities = 100/426 (23%), Positives = 226/426 (53%), Gaps = 25/426 (5%)
Query: 58 RQKERERRREKRQTERET---DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
++K+ +R E+ ER+ + R +++ K + +E+ + E E+ ++
Sbjct: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
Query: 115 RQREKERNRQKERERETEREGER-GRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
+R+ ER + +++ + E + G++ Q+ + + + E E + +++++ + R
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE--ENELWNRLNQQQEEKMWR 304
Query: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
+K +E E+ QE+ E+ R++E++ + ++ R E E+E + + + ++E
Sbjct: 305 QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
Query: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
+R E EK+ + E+ E++K RE+E R + R++E+ ++ + K R+ E+
Sbjct: 365 MRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 424
Query: 294 DRETE-------RKRERQRERERERERNRKRERERERE---RERERQRETE---RDREK- 339
RE E +K RQ E+ E+E+ R+ E+ +E+E R+ E+ RE E R +EK
Sbjct: 425 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKM 484
Query: 340 -ERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR-DRDRQ 397
E+E+ RK++ ++ R+ + +E + RE+E + R + RE+EE+ R++ ++ R+
Sbjct: 485 HEQEKIRKQEEKVWRQEEKMHDQE---EKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541
Query: 398 KERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457
+E Q ++++ G++E + Q + + R+ E+ RE+ + +QK + R++E + Q +
Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI 601
Query: 458 RKRSTL 463
R++ +
Sbjct: 602 REQEEM 607
Score = 134 bits (336), Expect = 3e-31
Identities = 96/326 (29%), Positives = 183/326 (56%), Gaps = 17/326 (5%)
Query: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTD-- 110
++E +++ E EK + R + + EK R + H E+++ RE+E +RQ +
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH-EQEKIREQEEKRQEEEK 404
Query: 111 -RERDRQREKERN--RQKERERETE---REGERGRDRQTDGQRERERQRDAEKERERQTD 164
RE+++++E+E RQ+E+ RE E RE E+ RQ + E+E+ R+ EK RQ
Sbjct: 405 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK---RQEQ 461
Query: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETER 224
E RQ E+ R++E E + +++ E+E+ R++E K R E+ ++E E+ E E +
Sbjct: 462 EEMWRQEEKIREQE-EIWRQKEKMHEQEKIRKQEEKVW-RQEEKMHDQE-EKIREQEEKM 518
Query: 225 KRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTD 284
RQ ++ R+++ K + EK E+E + + E+ E+E E+ +++++ RRQ+E+ R+ +
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE-EKMQEQEKMRRQEEKIREQE 577
Query: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK 344
K + + E+ RE E K Q E+ RE+E + + E+ E+E E+ E E +++ E+
Sbjct: 578 EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE-EKMCEQEEKMQEQEEKM 636
Query: 345 RKRQTEMDRERNRQTGREGRRQAERE 370
R+++ +M + R +E + Q +E
Sbjct: 637 RRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 109 bits (273), Expect = 6e-24
Identities = 70/282 (24%), Positives = 151/282 (53%), Gaps = 26/282 (9%)
Query: 52 DDRERNRQKERERRREKRQTE-----RETDRKRE-----RRREKDRHRKRDRHRERQRDR 101
+ E+ +++E+ R +EKRQ + R+ ++ RE R +EK R+ ++ E+++ R
Sbjct: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453
Query: 102 EKERERQTD---RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKE 158
E+E+ ++ + R+ ++ RE+E + R++E E E+ R ++ R+ E+ D
Sbjct: 454 EEEKRQEQEEMWRQEEKIREQE---EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD---- 506
Query: 159 RERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERET 218
Q ++ R+++ + RQ+E+ RE+ + R + E+ RE+E +++ + G + E+ +E
Sbjct: 507 ---QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
Query: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKE 278
E + +RQ ++ R+++ K ++EK E+E + E+ +E+E ++ Q+E
Sbjct: 564 E---KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 279 RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
+ + + K Q + E+ R E K Q R R++E + +E
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 107 bits (268), Expect = 2e-23
Identities = 64/276 (23%), Positives = 150/276 (54%), Gaps = 10/276 (3%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
++ +R+ + + ++E ++ E+ RE+ + RE ++K R+ EK +++ R
Sbjct: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453
Query: 94 HRERQRDREKERERQTDRERDRQ---REKERNRQKERERETEREGERGRDRQTDGQRERE 150
E+++++E E RQ ++ R+++ R+KE+ ++E+ R+ E + R ++ D + E
Sbjct: 454 EEEKRQEQE-EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD---QEE 509
Query: 151 RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGR 210
+ R+ E++ RQ ++ R+++ + Q+E+ RE+ + + E+ E+E K +++ R
Sbjct: 510 KIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR-- 567
Query: 211 ERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDR 270
R+ E+ E E + + Q ++ R+++ K + EK E+E + + E+ E+E +
Sbjct: 568 -RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 626
Query: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
++ + Q+E+ R+ + K + R R+ E K + +E
Sbjct: 627 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 94.0 bits (232), Expect = 4e-19
Identities = 96/417 (23%), Positives = 196/417 (47%), Gaps = 34/417 (8%)
Query: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR-EK 119
+ ++++ T ET +D + +H+E R RE E + T R Q+ E
Sbjct: 84 DTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALR-RELEAQVHTIRILTCQKTEL 142
Query: 120 ERNRQKERERETEREGERGRD---RQTDGQR---ERERQRDAEKERERQTDRERQRQTER 173
+ + + EGE RD R D + E E+ A ++++ DR + T+
Sbjct: 143 QMALYYSQHAVKQLEGE-ARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKE 201
Query: 174 NRQKEREREKNRQERRE-RERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
E +N E +E+ + + K + SE+ + +E + + ER + ++
Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261
Query: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Q + + ++ + + E ++ R + ++ RQ+E+ ++ + K Q + E
Sbjct: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE 321
Query: 293 RDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
+ RE Q E+ RE+E +R+ E E+E + +R+ E EKE + +R + +
Sbjct: 322 KIRE-------QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWE 374
Query: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE----RQTEKDR 408
+E E R+ E E+ E+E+ R+ +R+E E+ R++++++E+E RQ EK R
Sbjct: 375 KE-------EKIRELE-EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 426
Query: 409 DGQ---RETEKQ--REREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
+ + RE EK+ R+ EK E E+ RE + +E+++ ++ + + + RQ+++
Sbjct: 427 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Score = 80.5 bits (197), Expect = 4e-15
Identities = 56/215 (26%), Positives = 118/215 (54%), Gaps = 16/215 (7%)
Query: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR---------HRERQRDRE 102
++ +R Q+E R+ EK + + E R++E+ E+++ RK++ H + ++ RE
Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE 513
Query: 103 KERERQTDRERDRQREKERNRQKERERETE---REGERGRDRQTDGQRERER-QRDAEKE 158
+E + E+ R++E++ Q+E+ RE E +E E Q + +E+E+ +R EK
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Query: 159 RERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERET 218
RE Q ++ R+++ + Q+E+ E+ + R + E +E+E K ++ E+ E+E E+
Sbjct: 574 RE-QEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ-EEKMCEQE-EKMQ 630
Query: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASE 253
E E + +RQ ++ +++ + ++ EK E + E
Sbjct: 631 EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 34.7 bits (78), Expect = 0.26
Identities = 20/103 (19%), Positives = 50/103 (48%)
Query: 32 GSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKR 91
G QE + ++ ++E ++++E+ RE+ + E + K + E + ++
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE 613
Query: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETERE 134
+ ++ E+E + Q E+ R++E++ Q+ R R+ E +
Sbjct: 614 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 148 bits (374), Expect = 1e-35
Identities = 101/430 (23%), Positives = 224/430 (52%), Gaps = 25/430 (5%)
Query: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
E ++K E + E + E E + +E R + D+ Q + +E+E Q +
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 115 RQREKERNRQKERERETEREGE----RGRDRQTDGQ-RERERQ-RDAEKERERQTDRERQ 168
+ RE+E +++ + E+EG+ G+ R+ +GQ RE+E Q R+ E + Q + R+
Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
Query: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE----RGRERERERETETETER 224
++ + Q+ + RE+ Q R + + RE+E + ++ + G+ RE+E + + +
Sbjct: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
Query: 225 KRQTDRERDRQRKTEREREKQ-AERERASERETERDKERERERDRDRDRDRRQKERERQT 283
R+ + + Q E+E+Q E+E +++ E+ E+E + + ++ Q+E+ ++
Sbjct: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
Query: 284 DRKRQRRTERDRETERKRERQRERERERERN---RKRERERERER-ERERQRETERDREK 339
+ + Q++ E+ R+ E + Q E+ RE+E +K + E+E + E+E Q + ++ +
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKE 399
E+E + + Q E RE+ Q G++ + E++ + ++++ +E + E++ +Q+E
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366
Query: 400 RER-QTEKDRDGQRETEKQREREKDRESERG---------RERGREREKQKGRERDRERQ 449
+ R Q E+ R + + KQ E+ + +E + G +E+ RE+E+Q G ++++ R+
Sbjct: 367 QVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRK 426
Query: 450 TDRQAGRQRK 459
+ G Q++
Sbjct: 427 QEEHMGEQKE 436
Score = 88.6 bits (218), Expect = 2e-17
Identities = 47/220 (21%), Positives = 122/220 (55%), Gaps = 4/220 (1%)
Query: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
++E QK+ E+ E+ + R+ + + + E+ + ++ ++ ++ R++E + + E
Sbjct: 210 EQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEE 269
Query: 113 RDRQREKERNRQKERERETEREGERGRD--RQTDGQRERERQRDAEKERERQTDRERQRQ 170
+ R++E++ +QKE+ + E+ GE+ Q + RE+E Q ++E+ R+ + + +Q
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ 329
Query: 171 TERN-RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTD 229
E+ QKE+ E+ Q ++ E+ E+E + + + E+ R++E + + E RK++
Sbjct: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQ-KQEEQVRKQEEQMRKQEEQMRKQEEQ 388
Query: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
+ ++ E++ + ++E+ E+E + +++E+ R ++
Sbjct: 389 MRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
Score = 86.7 bits (213), Expect = 6e-17
Identities = 63/293 (21%), Positives = 142/293 (48%), Gaps = 20/293 (6%)
Query: 187 ERRERERQREKENKTEDRHSERGRERERERETETE----------TERKRQTDRERDRQR 236
+ + E Q E + ++ + +E +R+ ET+ E++ Q + + R
Sbjct: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR 69
Query: 237 KTE---REREKQAERERASERETE---RDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
+ E RE+E Q + RE E R++E + + R++ + RE++ + Q
Sbjct: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 129
Query: 291 TERDRETERKRERQRERERERERNRKRERERERE---RERERQRETERDREKERERKRKR 347
R++E + + + + RE+E + + + RE+E RE+E Q + + +E+E + +
Sbjct: 130 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 189
Query: 348 QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
Q E+ Q G + + E+E + +++ ++ +E + R+++ Q+E+ ++ E+
Sbjct: 190 QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQ 249
Query: 408 RDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Q E +++E + + E+ RE+ + KQK + ++E QT Q + R++
Sbjct: 250 VQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK-EQTEQEEQTGEQEEQMREQ 301
Score = 82.8 bits (203), Expect = 8e-16
Identities = 60/290 (20%), Positives = 143/290 (49%), Gaps = 17/290 (5%)
Query: 178 EREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRK 237
E +EKN + + E + ++++ + E R+ E ++ + + R+ + + Q
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 238 TEREREKQAERERASERETERDKERERERDRDRDRDRRQKE---RERQTDRKRQRRTERD 294
RE+E Q + RE E + + R+++ R++E RE++ + Q R+
Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
Query: 295 RETERKRERQRERERERERNRKRERERERE---RERERQRETERDREKERERKRKRQTEM 351
+E + + + + RE+E + + + RE+E RE+E Q + + +E+E + + Q
Sbjct: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
Query: 352 DRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQ 411
RE+ Q G + + E+E + + ++ +E + E++ +Q+E+ + E+
Sbjct: 187 VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE----- 241
Query: 412 RETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRS 461
+ +KQ E+ + +E E+ R++E+Q + ++ R+ + Q +Q++++
Sbjct: 242 -QVQKQEEQVQKQE-----EQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
Score = 77.8 bits (190), Expect = 3e-14
Identities = 47/218 (21%), Positives = 113/218 (51%), Gaps = 20/218 (9%)
Query: 32 GSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD--RKRERRREKDRHR 89
G QE ++ Q K + + +Q+E+ R +E++ E+E +++E+ ++++
Sbjct: 237 GEQEEQVQKQEEQVQKQ----EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTG 292
Query: 90 KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRER 149
+++ Q ++ +E+E Q + ++ RE+E K+ E+ E++ + ++ Q +
Sbjct: 293 EQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE---QMWK 349
Query: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209
+ ++ E+E + Q E+ R +Q+E+ R++ Q R++ E+ R++E + ++ + G
Sbjct: 350 QEEQMGEQEEQMQKQEEQVR-----KQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMG 404
Query: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAE 247
++E+ RE E Q ++++ RK E +Q E
Sbjct: 405 EQKEQMREQE------EQMGEQKEQMRKQEEHMGEQKE 436
Score = 72.0 bits (175), Expect = 1e-12
Identities = 60/267 (22%), Positives = 134/267 (50%), Gaps = 22/267 (8%)
Query: 201 TEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDK 260
T + E+ E + E + ETE+ ++ +RK E ++ + + E+E +
Sbjct: 5 TNEELKEKNAELQEELQL-VETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQV-- 61
Query: 261 ERERERDRDRDRDRRQKE---RERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
R+++ R++E RE++ + Q R++E + + + + RE+E + +
Sbjct: 62 -------REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 114
Query: 318 ERERERE---RERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
+ RE+E RE+E Q + + +E+E + + Q RE+ Q R Q + RE+E
Sbjct: 115 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV----REQEGQVREQE 170
Query: 375 RERDRQSAREREERERDRDRDRQK-ERERQTEKDRDGQRETEKQREREKDRESERGRERG 433
+ Q + RE+ + R+++ Q E+E Q + + E E+Q ++++++ E+ E+
Sbjct: 171 GQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ-EEQM 229
Query: 434 REREKQKGRERDRERQTDRQAGRQRKR 460
R++E+Q G + ++ ++ + Q +Q ++
Sbjct: 230 RKQEEQMGEQEEQVQKQEEQVQKQEEQ 256
Score = 53.5 bits (127), Expect = 5e-07
Identities = 54/225 (24%), Positives = 104/225 (46%), Gaps = 26/225 (11%)
Query: 319 RERERERERERQR-ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER 377
+E+ E + E Q ETE+ + ++ KR+ E D+ Q G+ R Q + RE+E +
Sbjct: 10 KEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQV-REQEGQVREQEGQV 68
Query: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Q + RE+ + R+++ Q + ++++GQ +Q + +++E + + G+ RE
Sbjct: 69 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQ--VREQEGQVREQEGQVREQEGQVRE 126
Query: 438 KQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDP 497
Q+G+ R++E Q Q G+ R++ G V+ + +R +
Sbjct: 127 -QEGQVREQEGQVREQEGQVREQE-------------GQVREQEGQ----VREQEGQVRE 168
Query: 498 KAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRPSG 542
+ R G+ + G+V R E ++GE+ GQ GE G
Sbjct: 169 QEGQVREQEGQ-VREQEGQV---REQEGQMGEQEGQMGEQEEQMG 209
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 144 bits (364), Expect = 2e-34
Identities = 137/500 (27%), Positives = 223/500 (44%), Gaps = 66/500 (13%)
Query: 24 LDFSRRRPGSQESPRRRGLGQAHKDADGDDR--ERNRQKERERRREKRQTERETDRKRER 81
L+ R +E R + KD+ DR E +K E E R+ E + +R
Sbjct: 863 LEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGE 922
Query: 82 RREKDRHRKRDRHRERQR--DREKERERQTDRERDRQREKERNRQKERERETEREGERGR 139
R++DR +RD R R+ D ++E + D +R +R + +R R E +R RG
Sbjct: 923 GRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGA 982
Query: 140 D------RQTDGQRERERQRDAEKERERQTDRER--QRQTERNRQKEREREKNRQERRER 191
D R TD R R D ++ R D +R +R + +R R +++R RR
Sbjct: 983 DDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGM 1042
Query: 192 ERQREKE------------NKTEDRHSERGRERERERETETETER------------KRQ 227
+ R N +DR RG + +R + +R +R
Sbjct: 1043 DDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRG 1102
Query: 228 TDRERDRQRKTERERE--KQAERERASERETERDKERERERDRDR-------DRDRRQKE 278
D +R +R + +R + A+ +R R E D+ R D DR DR R+ +
Sbjct: 1103 MDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGD 1162
Query: 279 RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDRE 338
R + + RE E+ RE RE + +RE +RE+ER+R+ Q E D++
Sbjct: 1163 DSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKD 1222
Query: 339 KERERKRKRQTEMDRE-RNRQTGREG--RRQAERERERERERDRQSAREREERERDRD-- 393
ERER R+R ++DRE R R+ EG RR E R+ R+ R+R++R R+RD
Sbjct: 1223 PERERDRER--DVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDR 1280
Query: 394 RDRQKERERQTEKDRDG-----QRETEKQREREKDRESERGRER---------GREREKQ 439
RD ++ R+ + ++DR G +RE R DR+ +R ER R+++
Sbjct: 1281 RDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRE 1340
Query: 440 KGRERDRERQTDRQAGRQRK 459
+ R+R+RE + ++ + R K
Sbjct: 1341 RDRDREREGEKEKASWRAEK 1360
Score = 138 bits (348), Expect = 1e-32
Identities = 130/481 (27%), Positives = 228/481 (47%), Gaps = 44/481 (9%)
Query: 56 RNRQKERERRREKRQTERETDRKRER---RREKDRHRKRDRHRERQRDREKERERQTDRE 112
+N +KE +R +RQT E + E +REK+ +R+ ++ R E+ER RQ +E
Sbjct: 559 KNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKE 618
Query: 113 RDRQR---EKERNRQK------ERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163
R+++R E E+ ++K E+ ++TE + +D + E + K+ E Q
Sbjct: 619 REKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVE-QL 677
Query: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG--RERERERETETE 221
++E++ ER + +E++ + + +R E K E R + ++E ER T +
Sbjct: 678 EKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQ 737
Query: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER 281
ER++ + + R E +R+ R +A+ + +K ++ E +R R +ER+R
Sbjct: 738 LEREKALEHKNRMSRMLE-DRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKR 796
Query: 282 QTDRKRQRRTERDRETERKRERQRER-------ERERERNRKRERE----RERERERERQ 330
Q RK +RR RE E + +R+ E ERER KRE E +ER ++ E
Sbjct: 797 Q--RKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEV 854
Query: 331 RETERDRE---KERERKRKRQTEM-DRERNRQTGREGRRQAERERERERERDRQSARERE 386
+R RE +ERER+R+ + + D +R+ R G R +E + E D + R
Sbjct: 855 ERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPP 914
Query: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGR--EREKQKGRER 444
E+E R R ++R + +++R + ++ RE + +R RG +R ++G E
Sbjct: 915 EKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEE 974
Query: 445 DRERQTDRQAGRQRKRSTLYVNPPPRTA---RSGVVQSDPNR-PTRGI-----RWKSSPE 495
DR + R R+T PP R A R +D +R P RG+ W+++ E
Sbjct: 975 DRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADE 1034
Query: 496 D 496
D
Sbjct: 1035 D 1035
Score = 138 bits (347), Expect = 2e-32
Identities = 142/539 (26%), Positives = 247/539 (45%), Gaps = 49/539 (9%)
Query: 60 KERERRREKRQTERETDRKRERRREKDRHRKRDRHRER------QRDREKERERQTDRER 113
+E+E + + T + ++E +R R + + +ER QR++E+ +R+ + ++
Sbjct: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
Query: 114 DRQREKERNRQKERERETER---EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ 170
R+ E+ER RQ+ +ERE ER E E+ + + + E+ ++ + + + D E +
Sbjct: 604 VRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEE 663
Query: 171 TERNRQKEREREKNRQERRE-RERQREKENKTEDRHSERGRERERERETETETERKRQTD 229
+ + ++ E+ +E++E +ER + +E K + + ER + E ++ E +R D
Sbjct: 664 LDPDFIMAKQVEQLEKEKKELQERLKNQEKKID--YFERAKRLEEIPLIKSAYEEQRIKD 721
Query: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289
+ Q++ ER Q ERE+A E + + E DRD R + R+ + K ++
Sbjct: 722 MDLWEQQEEERITTMQLEREKALEHKNRMSRMLE---DRDLFVMRLKAARQSVYEEKLKQ 778
Query: 290 RTERDRETERKR--ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
ER E R ER+R+R+ ER RE+E E +R E Q ER+ E+ER + KR
Sbjct: 779 FEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKERE-ERERAERAKR 837
Query: 348 QTEM----DRERNRQTGREGRRQAE---RERERERERDRQSAREREERERDR--DRDRQK 398
+ E+ +R + + +RQ E ERER RE +R+ R+ R DRD +
Sbjct: 838 EEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEG 897
Query: 399 ERERQTEKDRDGQR-ETEKQREREKDRESERGRERGREREKQKGRERDRE---RQTDRQA 454
+ E D + +R EK+ R + R+ +R R ER ++ G + DRE R D +
Sbjct: 898 TWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRV 957
Query: 455 GRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPED--PK--AASTRFPW---- 506
R+ P R +D +RP+ W+++ +D P+ A R W
Sbjct: 958 PRRGMDDDRGPRRGPEEDRFSRRGADDDRPS----WRNTDDDRPPRRIADEDRGNWRHAD 1013
Query: 507 -GRPAKASRGRVAGRRRW---EPRLGEKRGQGGEGRRPSGGFGTENPLSQAPSVFPGPR 561
RP + RG R W + G +RG + GG E + GPR
Sbjct: 1014 DDRPPR--RGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPR 1070
Score = 137 bits (346), Expect = 2e-32
Identities = 131/454 (28%), Positives = 201/454 (44%), Gaps = 51/454 (11%)
Query: 55 ERNRQKERERR----REKRQTER----ETDRKRERRREKDRHRKRDRHRERQRDREKERE 106
ER RQ++ ERR REK + E+ E K RE+ KR+ ++R K+ E
Sbjct: 793 ERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLE 852
Query: 107 RQTDRERDRQRE-KERNRQKERER-----ETEREGERGRDRQTDGQRERERQRDAEKER- 159
++R R+ E +ER R++E ER R+ R DR ++G + + D+E R
Sbjct: 853 EVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRG 912
Query: 160 --ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER--E 215
E++ R R +R+ +++ ER + + +RE + +DR RG + +R
Sbjct: 913 PPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPD---DDRVPRRGMDDDRGPR 969
Query: 216 RETETETERKRQTDRERDRQRKTERER--EKQAERERASERETERDKERERERDRDRDRD 273
R E + +R D +R R T+ +R + A+ +R + R + D+ R D DR
Sbjct: 970 RGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSW 1029
Query: 274 RRQKE----RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
R E R D + RR D E R +R R + R R + +R
Sbjct: 1030 RTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGP 1089
Query: 330 QRETERDREKER----ERKRKRQTEMDRE--RNRQTGREGRRQAERERE--RERERDRQS 381
+R + DR R +R +R + DR RN R RR AE +R R + DR S
Sbjct: 1090 RRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLS 1149
Query: 382 AREREERERDRDRDRQ-------------KERERQTEKDRDGQRETEKQREREKDRESER 428
R ++R R D + +E+E+ E+ RE+ ERE DRE ER
Sbjct: 1150 RRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKER 1209
Query: 429 GRER--GREREKQKGRERDRERQTDRQAGRQRKR 460
R+ E +K RERDRER DR+ +R R
Sbjct: 1210 DRDNQDREENDKDPERERDRERDVDREDRFRRPR 1243
Score = 136 bits (342), Expect = 6e-32
Identities = 131/468 (27%), Positives = 199/468 (42%), Gaps = 58/468 (12%)
Query: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRR---EKRQTERETDRKRERRR 83
S R G E RRG G+ +DR R +ER RR E R+ D R RR
Sbjct: 907 SEWRRGPPEKEWRRGEGR------DEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRR 960
Query: 84 EKDRHR------KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGER 137
D R + DR R D ++ R TD +R +R + +R R + +R R
Sbjct: 961 GMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRR 1020
Query: 138 GRD------RQTDGQRERERQRDAEKERER---QTDRERQRQTERNRQKEREREKNRQER 188
G D R D R R D ++ R +R R + +R R + +R R
Sbjct: 1021 GLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPR 1080
Query: 189 RERERQR-EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAE 247
R + R + +DR RG + +R + +R + + DR + E ++
Sbjct: 1081 RGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPW 1140
Query: 248 RERASERETERDKERERERDRDRDRD-------------RRQKERERQTDRKRQRRTERD 294
R +R + R + R D R ++K RE R+ R +
Sbjct: 1141 RNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEE 1200
Query: 295 RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
RE +R++ER R+ + +RE N K + ERER+RER+ RE R ++ R+ E
Sbjct: 1201 REWDREKERDRDNQ-DREENDK-DPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSS 1258
Query: 355 RNRQTGREGRRQAERERERERERDRQSAREREERERDRDR---DRQKERERQTEKDRDGQ 411
+ R+ R + +R RER+ DR+ RER + DRDR + ERE + R
Sbjct: 1259 WRDSSRRDDRDRDDRRRERD---DRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADD 1315
Query: 412 RETEKQRERE-----------KDRESERGRERGREREKQKGR-ERDRE 447
R+ ++ ER+ +DRE +R RER E+EK R E+DRE
Sbjct: 1316 RKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRE 1363
Score = 132 bits (333), Expect = 7e-31
Identities = 126/438 (28%), Positives = 194/438 (44%), Gaps = 59/438 (13%)
Query: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERER--RR---EKRQTERETDRKRERRRE 84
RP PRR DDR R E +R RR + R + R TD R RR
Sbjct: 951 RPDDDRVPRR---------GMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRI 1001
Query: 85 KDRHRKRDRHRERQRD--REKERERQTDRERDRQREKERNRQKER-ERETEREGERGRDR 141
D R RH + R R + +R + R D R R +R R + ER R
Sbjct: 1002 ADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWR 1061
Query: 142 QTDGQRERERQRDAEKERERQTDRER--QRQTERNRQKEREREKNRQERRERERQREK-E 198
D R R D ++ R D +R +R + +R R + +R RR + R
Sbjct: 1062 NADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWR 1121
Query: 199 NKTEDRHSERGRERERERETETETER-KRQTDRERDRQRKTE---------------RER 242
N +DR RG E +R + +R R+ D +R +R + RE+
Sbjct: 1122 NADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREK 1181
Query: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
EK E RE+ +ERE +R+++RDRD + +E E D +R+R ERD + E +
Sbjct: 1182 EKAREESWGPPRESRPSEEREWDREKERDRDNQDRE-ENDKDPERERDRERDVDREDRFR 1240
Query: 303 RQRE-----RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER-- 355
R R+ R E + R+ R +R+R+ +R R+R+ R+ + +R DR+R
Sbjct: 1241 RPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRR---RERDDRRDLRERRDLRDDRDRRG 1297
Query: 356 -----NRQTGREGRRQAERERERERERD--RQSAREREERERDRDRDRQKERERQ----- 403
R+ RR +R+ +R ERD R+ R+R+RDRDR++E E++
Sbjct: 1298 PPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWR 1357
Query: 404 TEKDRDGQRETEKQRERE 421
EKDR+ R T+ + + +
Sbjct: 1358 AEKDRESLRRTKNETDED 1375
Score = 122 bits (306), Expect = 9e-28
Identities = 122/429 (28%), Positives = 178/429 (41%), Gaps = 58/429 (13%)
Query: 29 RRPGSQESPRRRGLGQ---AHKDADGDDRE--RNRQKERERRR---EKRQTERETDRKRE 80
RR + RRG + + + AD DDR RN +R RR E R R D R
Sbjct: 959 RRGMDDDRGPRRGPEEDRFSRRGAD-DDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRP 1017
Query: 81 RRREKDRHR------KRDRHRERQRDREK-------ERERQTDRERDRQREKERNRQKER 127
RR D R DR R D ++ + ER + R D R R +R
Sbjct: 1018 PRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDR 1077
Query: 128 ERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ--RQTERNRQKEREREKNR 185
+ +RG R D R R D ++ R D +R R + +R R E +R
Sbjct: 1078 GPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDR 1137
Query: 186 QERRERERQREKENKTEDRHSERG-----------------RERERERETETETERKRQT 228
R + R +DR RG RE+E+ RE R+ +
Sbjct: 1138 GPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRP 1197
Query: 229 DRERDRQRKTEREREKQAERERASERETERDKERERERD------RDRDRDRRQKERERQ 282
ER+ R+ ER+R+ Q E + E ERD+ER+ +R+ RD RR E
Sbjct: 1198 SEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESS 1257
Query: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342
+ R RR +RDR+ +R+RER R+ R+ + +R+R R + E R + +
Sbjct: 1258 SWRDSSRRDDRDRD-DRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRAD-D 1315
Query: 343 RKRKRQTEMDRERNRQTGREGR-RQAERERERERERDRQSAREREERERDRDRDRQKERE 401
RK R E D R R R+ +R+RERE E+++ S R ++DR+ R
Sbjct: 1316 RKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWR--------AEKDRESLRR 1367
Query: 402 RQTEKDRDG 410
+ E D DG
Sbjct: 1368 TKNETDEDG 1376
Score = 118 bits (295), Expect = 2e-26
Identities = 120/490 (24%), Positives = 197/490 (40%), Gaps = 44/490 (8%)
Query: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
ER + E + R + +R+ R + + + ++ + E + E+ + ER
Sbjct: 739 EREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLE---ERK 795
Query: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
RQR++ER RE+E E E R ++ + ERER A++E E + +ER ++ E
Sbjct: 796 RQRKEERRITYYREKE-EEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEV 854
Query: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
+K+R+RE E ERER+RE+E + D R R +R++E + + D E
Sbjct: 855 ERKKRQREL---EIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEW-- 909
Query: 235 QRKTEREREKQAERERASERETERDKERERERDR----DRDR-------DRRQKERERQT 283
R + E R R+ +R R+ ER R D DR D R R
Sbjct: 910 -----RRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDD 964
Query: 284 DRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERER 343
DR +R E DR + R + R R + +R R + +R R + +R + +
Sbjct: 965 DRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDE 1024
Query: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403
R D +R + G + R R + ++A + R D DR R
Sbjct: 1025 DRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGP--RRG 1082
Query: 404 TEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
+ DR +R + R + + +RG RG + ++ R D +R R G + R
Sbjct: 1083 MDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRR--GAEDDRGPW 1140
Query: 464 YVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDP---------KAASTRFPWGRPAKASR 514
R +R D P RG + P P K + WG P ++
Sbjct: 1141 RNMDDDRLSRRA---DDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRES-- 1195
Query: 515 GRVAGRRRWE 524
R + R W+
Sbjct: 1196 -RPSEEREWD 1204
Score = 97.4 bits (241), Expect = 3e-20
Identities = 84/296 (28%), Positives = 143/296 (48%), Gaps = 28/296 (9%)
Query: 25 DFSRRRPGSQESPRRRGLGQAH---KDADGDDRERNRQKERER-----RREKRQTERETD 76
D RR + RRGL ++AD DDR R E +R + R + R D
Sbjct: 1096 DRGPRRGMDDDRGPRRGLDDDRGPWRNAD-DDRIPRRGAEDDRGPWRNMDDDRLSRRADD 1154
Query: 77 RKRERRREKDRHR------KRDRHRERQRDREKE----RERQTDRERDRQREKERNRQKE 126
+ RR + R K RE+++ RE+ RE + ER+ REKER+R +
Sbjct: 1155 DRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQ 1214
Query: 127 RERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ-TERNRQKEREREKNR 185
E +++ ER RDR+ D RE +R ++ R+ E + +R+ +R+R+ R
Sbjct: 1215 DREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRR 1274
Query: 186 QERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ 245
+ER +R RE+ + +DR RG ERE E R+ D +D R ER+ ++
Sbjct: 1275 RERDDRRDLRERRDLRDDR-DRRGPPLRSERE---EVSSWRRADDRKD-DRVEERDPPRR 1329
Query: 246 AERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKR 301
S +R+++R+RER+ ++++ + E++R++ R+ + T+ D T +R
Sbjct: 1330 VPPPALSR---DRERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDGWTTVRR 1382
Score = 94.4 bits (233), Expect = 3e-19
Identities = 86/317 (27%), Positives = 145/317 (45%), Gaps = 40/317 (12%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
D RR + RRG+ G D +R ++ + R R+ + DR R +
Sbjct: 1066 DRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRG-LDDDRGPWRNAD 1124
Query: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKE------------RERETE 132
DR +R +R R + +R + R D + + + + RE+E
Sbjct: 1125 DDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKA 1184
Query: 133 REGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERE 192
RE G R++ ERE R EKER+R + + R+++RER+ +R++R R
Sbjct: 1185 REESWGPPRESRPSEEREWDR--EKERDRDNQDREENDKDPERERDRERDVDREDRFRRP 1242
Query: 193 RQR--------EKENKTED--RHSERGR-ERERERETETETERKRQTDRERDRQRKTER- 240
R E+ + D R +R R +R RER+ + +R +RDR+ R
Sbjct: 1243 RDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRS 1302
Query: 241 EREKQAERERASERETERDKERE---------RERDRDRDRDRRQKERERQTDRKRQRRT 291
ERE+ + RA +R+ +R +ER+ RDR+RDRD R++E E++ K R
Sbjct: 1303 EREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRD-REREGEKE---KASWRA 1358
Query: 292 ERDRETERKRERQRERE 308
E+DRE+ R+ + + + +
Sbjct: 1359 EKDRESLRRTKNETDED 1375
Score = 70.1 bits (170), Expect = 6e-12
Identities = 96/421 (22%), Positives = 176/421 (41%), Gaps = 96/421 (22%)
Query: 205 HSERGRERERERETETETERKRQTDRERDRQRKTEREREK-------QAERERASERETE 257
H + +E + + + R+ + +R+T ER++ Q E+E +RE E
Sbjct: 541 HILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAE 600
Query: 258 RDKERERERDRDR-DRDRRQKERERQTDRKRQRRTERDRETERKR--------------- 301
K R+ E +R R + R+KER Q + +++T R+R + K+
Sbjct: 601 LQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIED 660
Query: 302 -----------------ERQRERERERERNRKR---------------------ERERER 323
E++++ +ER +N+++ E +R +
Sbjct: 661 LEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIK 720
Query: 324 ERERERQRETER------DREKERERKRKRQTEMDRERN---------RQTGREGRRQAE 368
+ + Q+E ER +REK E K R + M +R+ RQ+ E + +
Sbjct: 721 DMDLWEQQEEERITTMQLEREKALEHK-NRMSRMLEDRDLFVMRLKAARQSVYEEKLKQF 779
Query: 369 RERERERERDRQSAREREERERDR---DRDRQKERERQTEKDRDGQRETEKQREREKDRE 425
ER E +R R+R+ +E R R++++E +R+ E+ +RE ++ ER K E
Sbjct: 780 EERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREE 839
Query: 426 SERG-RERGREREKQKGRERDRERQ-TDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNR 483
R +ER ++ E+ + ++R RE + +R+ R+ +R + + +R G +R
Sbjct: 840 ELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWG------DR 893
Query: 484 PTRGIRWKSSPEDPKAASTRFPWGRPAKASR---GRVAGRRRWEPRLGEKRGQGGEGRRP 540
+ G W+ PE A + + G P K R GR R +R E R P
Sbjct: 894 DSEG-TWRKGPE----ADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREP 948
Query: 541 S 541
S
Sbjct: 949 S 949
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 144 bits (364), Expect = 2e-34
Identities = 101/423 (23%), Positives = 225/423 (53%), Gaps = 17/423 (4%)
Query: 54 RERNRQKERERRR-EKRQTERETDRK-RERRREKDRHRKRDRHRERQRDREKERERQTDR 111
+E R+ ER + ++Q + E D +E + + + + E +++E + R
Sbjct: 306 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 365
Query: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
+ ++ +E E Q++ E+ E+E E+ R+++ +R+ E + E++ RQ + +++
Sbjct: 366 QEEKIQEWEEKIQEQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424
Query: 172 ERNRQKER--EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTD 229
+ RQ+E E+E+ +E E+ ++EK + E++ E + RE+E+ E E + RQ +
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 230 RERDRQRKTEREREKQ-AERERASERETERDKERERERD---RDRDRDRRQKERERQTDR 285
+ R+++ K + EK + E+ E+E R++E+ +E++ R ++ R Q+E RQ ++
Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 544
Query: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
++ E+ R+ E K RQ E+ ++E + RE+E + R+ E+ RE E ++ +E+E K
Sbjct: 545 IHEQE-EKIRKQEEKMWRQEEKMHDQEE-KIREQEEKVWRQEEKIREQE-EKIREQEEKI 601
Query: 346 KRQTEMDRERNRQTGREGRRQAERE-----RERERERDRQSAREREERERDRDRDRQKER 400
+ Q EM +E+ + G + + E+E +E + R + RE+E++ R+++ +++
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 661
Query: 401 ERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
E E++ + EK E+E+ + + + R +E + + R R+++ Q ++
Sbjct: 662 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Query: 461 STL 463
+ +
Sbjct: 722 AAI 724
Score = 132 bits (333), Expect = 7e-31
Identities = 99/425 (23%), Positives = 222/425 (52%), Gaps = 24/425 (5%)
Query: 58 RQKERERRREKRQTERET---DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
++K+ +R E+ ER+ + R +++ K + +E+ + E E+ ++
Sbjct: 248 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 307
Query: 115 RQREKERNRQKERERETEREGER-GRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
+R+ ER + +++ + E + G++ Q+ + + + E E + +++++ + R
Sbjct: 308 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE--ENELWNRLNQQQEEKMWR 365
Query: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
+K +E E+ QE+ E+ R++E++ + ++ R E E+E + + + ++E
Sbjct: 366 QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 425
Query: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
+R+ E EK+ + E+ E++K RE+E R + R++E+ ++ + K R+ E+
Sbjct: 426 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 485
Query: 294 DRETERK-RE------RQRERERERERNRKRERERERE---RERERQRETE---RDREKE 340
RE E K RE RQ E+ E+E+ R+ E+ +E+E R+ E+ RE E R +EK
Sbjct: 486 IREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI 545
Query: 341 RERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR-DRDRQKE 399
E++ K + + ++ ++ + + RE+E + R + RE+EE+ R++ ++ R++E
Sbjct: 546 HEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE 605
Query: 400 RERQTEKDRDGQRETEKQREREKDRESE----RGRERGREREKQKGRERDRERQTDRQAG 455
Q ++++ G++E + + EK +E E R E+ RE+EK+ + ++ R+ +
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665
Query: 456 RQRKR 460
Q ++
Sbjct: 666 EQEEK 670
Score = 107 bits (267), Expect = 3e-23
Identities = 70/274 (25%), Positives = 150/274 (54%), Gaps = 29/274 (10%)
Query: 52 DDRERNRQKERERRREKRQTE-----RETDRKRE-----RRREKDRHRKRDRHRERQRDR 101
+ E+ +++E+ R +EKRQ + R+ ++ RE R +E+ R+ ++ E+++ R
Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIR 514
Query: 102 EKERERQTD---RERDRQREKERN-RQKERERETEREGERGRDRQTDGQRERERQRDAEK 157
E+E+ ++ + R+ ++ RE+E RQKE+ E E E+ R ++ R+ E+ D
Sbjct: 515 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE---EKIRKQEEKMWRQEEKMHD--- 568
Query: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER--- 214
Q ++ R+++ + RQ+E+ RE+ + R + E+ RE+E T+++ + G + E+
Sbjct: 569 ----QEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 624
Query: 215 --ERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272
E+ E E + +RQ ++ R++++K + EK E+E + + E+ E+E + ++
Sbjct: 625 QEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 684
Query: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
+ Q+E+ R+ + K + R R+ E K + +E
Sbjct: 685 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 99.0 bits (245), Expect = 1e-20
Identities = 96/414 (23%), Positives = 196/414 (47%), Gaps = 24/414 (5%)
Query: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR-EK 119
+ ++++ T ET +D + +H+E R RE E + T R Q+ E
Sbjct: 145 DTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALR-RELEAQVHTIRILTCQKTEL 203
Query: 120 ERNRQKERERETEREGERGRD---RQTDGQR---ERERQRDAEKERERQTDRERQRQTER 173
+ + + EGE RD R D + E E+ A ++++ DR + T+
Sbjct: 204 QMALYYSQHAVKQLEGE-ARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKE 262
Query: 174 NRQKEREREKNRQERRE-RERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
E +N E +E+ + + K + SE+ + +E + + ER + ++
Sbjct: 263 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 322
Query: 233 DRQRKTE---REREKQAERERASERETER----DKERERERDRDRDRDRRQKERERQTDR 285
Q + + +E + + + +A E E ++++E + R ++ + +E+ ++ +
Sbjct: 323 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE 382
Query: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
K + + E+ RE E K RQ E E+E +R+ E E+E + +R+ E EKE E+ R
Sbjct: 383 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKIR 441
Query: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTE 405
+ + +M + + E R++ E+ RE+E+ +++++ R+E + ++ +E+E +
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Query: 406 KDRDGQRETEKQREREKDRESE---RGRERGRERE---KQKGRERDRERQTDRQ 453
+ + E EK RE EK +E E R E+ RE+E +QK + ++E + +Q
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555
Score = 78.6 bits (192), Expect = 2e-14
Identities = 53/230 (23%), Positives = 118/230 (51%), Gaps = 22/230 (9%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
QE R Q ++ + + Q+E R++EK + E RK+E + + + D
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD- 568
Query: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
Q ++ +E+E + R+ ++ RE+E +K RE+E E+ R+++ Q + E+
Sbjct: 569 ----QEEKIREQEEKVWRQEEKIREQE---EKIREQE-----EKIREQEEMTQEQEEKMG 616
Query: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
+ E++ Q ++ ++++ + RQ+E+ RE+ ++ R + E+ RE+E ++ +
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE---------Q 667
Query: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
E+ E E + Q ++ ++++ K R+ EK E+E ++ E+ +E +
Sbjct: 668 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 717
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 143 bits (360), Expect = 5e-34
Identities = 109/439 (24%), Positives = 174/439 (39%), Gaps = 45/439 (10%)
Query: 66 REKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQK 125
REK + E R + + R R + + R + R R R R R
Sbjct: 253 REKSYSPTEMS-SRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNH 311
Query: 126 ERERETEREG---ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE 182
R R R+G + GR Q+ R + + + R R R RN KER
Sbjct: 312 SRARSRTRKGILSQMGRHSQS-----RSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHS 366
Query: 183 KNRQERRERERQREKENKTEDRHSERG-----RERERERETETETERKRQTDRERDRQRK 237
+R +ER+ + + E S+ G R+ R R +R R + R R
Sbjct: 367 HSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRS 426
Query: 238 TEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRET 297
R K + R+ RD+ R R ++ RD R + + DR R R ++R+
Sbjct: 427 RSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHS-RSRSPNKARDRSRSRSPSKERDH 485
Query: 298 ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR 357
+ +ER+ R R+ +ER+ + R ++R+ R R +ER+R++ ++ER+R
Sbjct: 486 SQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDR 545
Query: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
R + E RQS +ER+R R R KERER+ + R E +
Sbjct: 546 SQSRSPSEEREH---------RQSRSPSKERDRRRWRSPSKERERR--QSRSSSEERDHS 594
Query: 418 REREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVV 477
R R +++S R R +EK R R ++ + R +
Sbjct: 595 RSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSK----------------- 637
Query: 478 QSDPNRPT--RGIRWKSSP 494
+SDP++ T R WK SP
Sbjct: 638 ESDPSQSTVPRSPDWKRSP 656
Score = 139 bits (351), Expect = 6e-33
Identities = 98/403 (24%), Positives = 161/403 (39%), Gaps = 29/403 (7%)
Query: 27 SRRRPGSQE---SPRRRGLG---QAHKDADGDDRERNRQKERERRRE---KRQTERETDR 77
+R RP S SPRR G + H +RN + R R R+ + R
Sbjct: 274 TRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSR 333
Query: 78 KRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGER 137
+ + +++ R R R R +ER R +E++ +E+ R
Sbjct: 334 SHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSG 393
Query: 138 GRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREK 197
++Q D R R + ++ R R + R R R+ K R+ ++R + R+R R +
Sbjct: 394 SPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSR 453
Query: 198 E-NKTEDRHSERGRERERERETETETERKRQTDRERDRQR--KTEREREKQAERERASER 254
NK D R + R+R R R +ERD + +ER+ + R + ER
Sbjct: 454 SPNKARDHSRSRSPNKARDRS------RSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507
Query: 255 ETERDKERERERDRDRDRD---RRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311
+ + + +ERD R R RQ+ + R +++R R R ER+ + R +ER
Sbjct: 508 QCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKER 567
Query: 312 ERNRKRERERERERERERQRETERDREKER--------ERKRKRQTEMDRERNRQTGREG 363
+R R R +ERER + R ERD + R R R E R+R +EG
Sbjct: 568 DRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEG 627
Query: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK 406
R +E + + + + +R R + R K
Sbjct: 628 NHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSK 670
Score = 139 bits (349), Expect = 1e-32
Identities = 94/390 (24%), Positives = 165/390 (42%), Gaps = 10/390 (2%)
Query: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
SR + +Q S R R Q+H + R R+ ++R R + + + + R K
Sbjct: 264 SRVKSYNQASTRSRP--QSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG 321
Query: 87 RHRKRDRHRE-RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG 145
+ RH + R + K + + R R RN KER R + RD +
Sbjct: 322 ILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSS 381
Query: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH 205
+E R +Q D R R N+ ++R R ++ + R+R R R NK D
Sbjct: 382 SPRKESGRSQSGSPNKQRDHSRSRSP--NKARDRSRSRSPYKARDRSRSRSP-NKARDCS 438
Query: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE 265
R + R+R + R R R + +R R + +ER + KER+
Sbjct: 439 RSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHR 498
Query: 266 RDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERER 325
R R ++R Q + R + ++R R R R ++R+R++ R +ER+R + R ER
Sbjct: 499 RSRSPSKER-QCRQSRSSSKERDHR--RSRSPSKERQRRQSRSPNKERDRSQSRSPSEER 555
Query: 326 ERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARER 385
E + R ++R++ R R ++ E + R+ R+ R ++ R R S++E+
Sbjct: 556 EHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEK 615
Query: 386 -EERERDRDRDRQKERERQTEKDRDGQRET 414
R R ++ + R + K+ D + T
Sbjct: 616 AHSRSRTPSKEGNHSQSRTSSKESDPSQST 645
Score = 77.8 bits (190), Expect = 3e-14
Identities = 48/213 (22%), Positives = 88/213 (41%), Gaps = 5/213 (2%)
Query: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREK 85
+R R S+ + R Q + D R+R +ER+ R+ R + +E D +R R K
Sbjct: 470 ARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSK 529
Query: 86 DRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG 145
+R R++ R ++RDR + R +RE + R+ KER+R R + R+R+
Sbjct: 530 ERQRRQSRSPNKERDRSQSRSPSEEREH----RQSRSPSKERDRRRWRSPSKERERRQSR 585
Query: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH 205
ER + +Q+ R R + + + R R +++ + R KE+
Sbjct: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQST 645
Query: 206 SERGRERERERETETETERKRQTDRERDRQRKT 238
R + +R + + R + T
Sbjct: 646 VPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPST 678
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 141 bits (355), Expect = 2e-33
Identities = 122/454 (26%), Positives = 214/454 (47%), Gaps = 52/454 (11%)
Query: 52 DDRERNRQKERERRREKR-QTERET-DRKRERRREKDRHRKRDRHRERQRDREKERE--R 107
DD ER R+ R++R E R + ER R + E R R+R +ER R +++E +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 108 QTDR-ERDRQREKERNRQKERERETEREG-ERGRDRQTDGQRERERQRDAEKERERQTD- 164
TD+ E + Q K T+ EG + + +RE RQ+ ++ ERQ +
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 165 -------------RERQRQTERNRQKER-EREKNRQER---RERERQREKENKTEDRHSE 207
R Q T N E+ E+ ++RQER E E + K + R +E
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE 181
Query: 208 RGRERERERETETETERKRQTDRERD-----RQRKTERERE-----------KQAERERA 251
++ ++E+E E E + KR + E ++ TE + E E ++
Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQE 241
Query: 252 SERETERDKERERERDRDRDRDRRQKERERQTDRKRQR-RTERDRE--TERKRERQRERE 308
ERE D+ E+ + D++R + ER R +R+R + E+D++ ER R E+
Sbjct: 242 EEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKA 301
Query: 309 RERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAE 368
+ER R+ ERER RE E++ ER R KE E++ + + +E ++ E RQ
Sbjct: 302 AAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE--RQRI 359
Query: 369 RERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRER-EKDRESE 427
+E E+ +RQ AR EE ++ + +++R +Q E+ + +ET+ + E+ E+ E +
Sbjct: 360 KEEEKRAAEERQRARAEEE---EKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGK 416
Query: 428 RGRERGREREKQKG---RERDRERQTDRQAGRQR 458
E+ + +K + +++ E+ T QA R++
Sbjct: 417 WVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREK 450
Score = 136 bits (342), Expect = 6e-32
Identities = 103/433 (23%), Positives = 208/433 (48%), Gaps = 23/433 (5%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
+E P+R +G+ + +++ Q+E K + K+E RE+
Sbjct: 195 EEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEIS-- 252
Query: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
H E+ + +KER + ER R +ER R K E++ + ER R E+
Sbjct: 253 HHEKMEEEDKER---AEAERARLEAEERERIK-AEQDKKIADERAR------IEAEEKAA 302
Query: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
E+ER +RER R+ E+ +ER+R K ++R ERQR KE E++ + R+R
Sbjct: 303 AQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKE---EEKRAAEERQRI 359
Query: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKER-ERERDRDRDR 272
+E E ER+R E ++ + E++R KQ E ++ + +ET+ E+ E++ +
Sbjct: 360 KEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVN 419
Query: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE 332
+++ +E + QT +++ E+ + + KRE+ +E + ++ ++ + ++++E + + +
Sbjct: 420 EKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVK 479
Query: 333 TERDREKERERKRKRQTEMDRERNRQT----GREGRRQAERERERERERDRQSAREREER 388
+ DR+K + + E + + T R G R + +E E ++ + EE
Sbjct: 480 SFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEEL 539
Query: 389 ERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE---SERGRERGREREKQKGRERD 445
R R +E E+ +K ++ E E+ +++ ++R E + R +E +K RE +
Sbjct: 540 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEE 599
Query: 446 RERQTDRQAGRQR 458
+R+ + R+R
Sbjct: 600 EKRRLKEEIERRR 612
Score = 133 bits (335), Expect = 4e-31
Identities = 104/401 (25%), Positives = 191/401 (47%), Gaps = 24/401 (5%)
Query: 33 SQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRK-- 90
S E P+ Q + G D + +K E +E+ + ER ER R K K
Sbjct: 234 SSEEPK-----QEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKI 288
Query: 91 ---RDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
R R ++ +ERER+ ER+R RE+E+ +ER+R E E +RQ R
Sbjct: 289 ADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQ----R 344
Query: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207
+E ++ A +ER+R + E++ ER R + E EK + E ++R +Q E++
Sbjct: 345 IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKI 404
Query: 208 RGRERERERETETETERKRQTDRERD---RQRKTEREREKQAERERASERETERDKERER 264
+G + E++ E + E+K Q D+ + +++ E+ + QA+RE+ E + KE +
Sbjct: 405 KGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIK 464
Query: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERE 324
+ +D++ +++ + DRK+ + + E + + E R R +E
Sbjct: 465 DEKIKKDKEPKEEVKSFM-DRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKE 523
Query: 325 RERERQRETERDREKERERKRKRQTEMDR-ERNRQTGREGRRQAERERERERERDRQSAR 383
E Q E + E R+R+ +TE + E+ +Q +E + E E +++RE R+
Sbjct: 524 AEGAPQ--VEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELE-ELKKKREERRKVLE 580
Query: 384 EREERERDRDRDR--QKERERQTEKDRDGQRETEKQREREK 422
E E+R + + DR ++E E++ K+ +R E +R+K
Sbjct: 581 EEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 621
Score = 129 bits (323), Expect = 1e-29
Identities = 114/514 (22%), Positives = 222/514 (43%), Gaps = 27/514 (5%)
Query: 23 PLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERR 82
P R GS E + + K+ +R R +ERER + ++ + +R R
Sbjct: 238 PKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEA 297
Query: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142
EK ++R+R +R+R +E E++ ER R +E+E+ +ER+R E E
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE--- 354
Query: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE---KEN 199
ERQR E+E+ +R+R R E + K E+++N+Q ++ +E K
Sbjct: 355 -------ERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGE 407
Query: 200 KTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ----AERERASERE 255
K E + + ++ +E + +T ++ E+ + + +RE+ ++ ++E + +
Sbjct: 408 KVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEK 467
Query: 256 TERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRET-ERKRERQRERERERERN 314
++DKE + E DR + E + Q + + T R R +E E
Sbjct: 468 IKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGA 527
Query: 315 RKRERERERERERERQRETERDR-EKERERKRKRQTEMDRERNRQTGREGRRQAERERER 373
+ E + E R R+ ETE + EK ++++++ E++ + ++ R + E +R +
Sbjct: 528 PQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRK 587
Query: 374 ERERDRQSAREREER--ERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRES----- 426
+ E DR+ E E+R + + +R R + E++ + DG + +K + + S
Sbjct: 588 QEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIE 647
Query: 427 ERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTR 486
ER + +K G + + + + ++ T + + SD P
Sbjct: 648 ERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAASDLPVPAE 707
Query: 487 GIR-WKSSPEDPKAASTRFPWGRPAKASRGRVAG 519
G+R KS E S+ G P K + G G
Sbjct: 708 GVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVG 741
Score = 124 bits (311), Expect = 2e-28
Identities = 103/448 (22%), Positives = 203/448 (45%), Gaps = 55/448 (12%)
Query: 28 RRRPGSQESPRRR----GLGQAHKDADGDDRERNRQKERERRREKRQTERETDR---KRE 80
RRR QE R++ LGQ + + + +E + Q E + + +R
Sbjct: 41 RRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERL 100
Query: 81 RRREKDRHRKRDRHRERQRDREK----------ERERQTDRERDRQREKERNRQKERER- 129
RRE+ R ++ ERQ++ + R Q D + EKE + +ER
Sbjct: 101 ARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY 160
Query: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT-----------ERNRQKE 178
E E + Q + R+ E + +KE+E + + + +R + E+ + +
Sbjct: 161 EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQ 220
Query: 179 RERE----KNRQERRERERQREKENKTEDR--HSERGRERERER----ETETETERKRQT 228
E KN Q E +Q E+ + D H E+ E ++ER E E + +
Sbjct: 221 EETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERI 280
Query: 229 DRERDRQRKTEREREKQAERERASERETERDKERERERDRDR---DRDRRQKERERQTDR 285
E+D++ ER R + E+ A ERE +ERER R+ ++ + +R KE E++
Sbjct: 281 KAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAE 340
Query: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
+RQR E ++ +R+R +E E+ R+R R E E+ + E +R+++ E ++
Sbjct: 341 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA--EEEEKAKVEEQKRNKQLEEKKHA 398
Query: 346 KRQTEMDRER----------NRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
++T++ E+ N + +E + Q +++ E+ + +RE+ + D+
Sbjct: 399 MQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTF 458
Query: 396 RQKE-RERQTEKDRDGQRETEKQREREK 422
+++E ++ + +KD++ + E + +R+K
Sbjct: 459 KKEEIKDEKIKKDKEPKEEVKSFMDRKK 486
Score = 120 bits (301), Expect = 4e-27
Identities = 103/399 (25%), Positives = 182/399 (45%), Gaps = 47/399 (11%)
Query: 80 ERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGR 139
ERRRE R ++ + E +R +R D E + RE+ R ++ER R+ + E G
Sbjct: 5 ERRRELRRQKREEMRLEAERIAY---QRNDDDEEEAARERRRRARQERLRQKQEEESLG- 60
Query: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQ-------TERNRQKEREREKNRQERRERE 192
Q Q E Q E + T Q + ER ++E R+K QE ER
Sbjct: 61 --QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALER- 117
Query: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERAS 252
Q+E + D R + E ET TE+E + ++ +ER
Sbjct: 118 -QKEFDPTITDASLSLPSRRMQNDTAENET---------------TEKEEKSESRQERYE 161
Query: 253 ERETERDKERERERD-RDRDRDRRQ-KERERQTDRKRQRRTERDRETERKRERQRERERE 310
ETE + ++ D RD + ++++ KE+E + + K +R + + + E E + +E
Sbjct: 162 IEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQE 221
Query: 311 RE-----RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRR 365
+N + E ++ E Q E ++ E + K + E +R R RE R
Sbjct: 222 ETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERE-RI 280
Query: 366 QAERERERERERDRQSARER---EERERDRDRDRQKERERQTEKDRDGQRETEKQREREK 422
+AE++++ ER R A E+ +ERER +R++ RE + + E+QR +E+
Sbjct: 281 KAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEK------RAAEERQRIKEE 334
Query: 423 DRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRS 461
++ + R+R +E EK+ ER R ++ +++A +R+R+
Sbjct: 335 EKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRA 373
Score = 30.4 bits (67), Expect = 4.9
Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Query: 407 DRDGQRETEKQREREKDRESER-GRERGREREKQKGRERDRERQTDRQAGRQRKRS 461
D + +RE +Q+ E E+ER +R + E++ RER R + +R +Q + S
Sbjct: 3 DFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEES 58
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 134 bits (337), Expect = 2e-31
Identities = 90/362 (24%), Positives = 191/362 (52%), Gaps = 19/362 (5%)
Query: 60 KERERRREKRQTERETDRKRERRREKDRHRKRDRHR----ERQRDRE-----KERERQTD 110
KE+ + +++ E+++ + K+ RK +R + ++Q E KE + +
Sbjct: 208 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 267
Query: 111 RERDRQREKER-NR-QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
+ + + E E NR +++E + R+ E+ ++R+ Q + E+ R+ E++ RQ + +
Sbjct: 268 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWE 327
Query: 169 RQTERNRQKER--EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226
++ + RQ+E E+E+ +E E+ ++EK + E++ E + RE+E+ E E + R
Sbjct: 328 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 387
Query: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
Q ++ R+++ K + E E+E + E+ E+E E ++ RRQ+E+ R+ ++K
Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK 447
Query: 287 RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDRE-----KER 341
+ + E+ RE E + Q E+ E+E + + +E+E + +R+ E+ RE +E+
Sbjct: 448 IREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507
Query: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE 401
E K + Q EM +E+ + + + E+E E+ +E++ + R+ E+ R RQ+E +
Sbjct: 508 EEKIREQEEMMQEQEEKMWEQEEKMCEQE-EKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Query: 402 RQ 403
Q
Sbjct: 567 MQ 568
Score = 132 bits (332), Expect = 9e-31
Identities = 94/408 (23%), Positives = 209/408 (51%), Gaps = 19/408 (4%)
Query: 58 RQKERERRREKRQTERET---DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
++K+ +R E+ ER+ + R +++ K + +E+ + E E+ ++
Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 234
Query: 115 RQREKERNRQKERERETEREGER-GRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
+R+ ER + +++ + E + G++ Q+ + + + E E + +++++ + R
Sbjct: 235 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE--ENELWNRLNQQQEEKMWR 292
Query: 174 NRQKEREREKNRQERRERER-QREKENKTEDRHSERGRERERERETETETERK-RQTDRE 231
+K +ERE+ QE+ E+ R Q EK + E+ E+ + R+ E E E K R+ + +
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352
Query: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
Q K + EK+ E E+ RE E+ +E+E + R ++ R Q+E+ R+ + Q +
Sbjct: 353 MHEQEKIREQEEKRQEEEKI--REQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQE 410
Query: 292 ERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEM 351
E+ E E K Q E +E+E +R+ E+ RE+E+ + +E+E K + Q EM
Sbjct: 411 EKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK---------KIREQEEKIREQEEM 461
Query: 352 DRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQ 411
+E+ + G + + E+E + + + ++ +E + RE+++ Q+E+ R+ E+ Q
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 521
Query: 412 RETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
E ++E + + E+ +E+ + +Q+ + R++E + +Q + ++
Sbjct: 522 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 122 bits (305), Expect = 1e-27
Identities = 96/405 (23%), Positives = 203/405 (50%), Gaps = 31/405 (7%)
Query: 75 TDRKRERRREKDRHRKRDR-----HRERQRDREKERERQTDRERDRQREKERNRQKERER 129
T +K+ R ++ ++RD +R D E + + +E+ + E E++ + +
Sbjct: 174 TQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 233
Query: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
E +R+ ER + Q++ + + D + + + Q Q E N R N+Q+
Sbjct: 234 ELKRKLERAKLLLP--QQQLQAEADHLGKELQSVSAKLQAQVEENELWNR---LNQQQEE 288
Query: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249
+ RQ EK + E++ E + E+ E E + +RQ + +++ K R+ E E+E
Sbjct: 289 KMWRQEEKIQEREEKIQE-----QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 343
Query: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ------RRTERDRETERKRER 303
RE E +K E+E+ R+++ R+++E+ R+ +++++ R+ E+ RE E K
Sbjct: 344 EKI-RELE-EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 401
Query: 304 QRERERERERNRKRERERERERERERQRETERDRE-----KERERKRKRQTEMDRERNRQ 358
Q E +E+E + E+ E+E E Q + E+ R +E+E+K + Q E RE+
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461
Query: 359 TGREGRRQAERERER-ERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
+ + E+E + E+E Q E+ R+ ++ R+++K+ Q EK R+ + ++Q
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 521
Query: 418 RER--EKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
E+ E++ + E+ +E+E++ R+ ++ R+ + + +Q ++
Sbjct: 522 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 120 bits (302), Expect = 3e-27
Identities = 80/320 (25%), Positives = 171/320 (53%), Gaps = 18/320 (5%)
Query: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERR-REKDRHRKRDRHRERQRDRE 102
QA D G + + K + + E R ++ E+ R++++ ++R+ + Q ++
Sbjct: 252 QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKI 311
Query: 103 KERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQ 162
+E+E + R+ + EKE +++ E E+E E+ R+ + + + + EK +E +
Sbjct: 312 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKIRELEEKMHEQEKIREQEEKRQEEE 370
Query: 163 TDRERQRQTERN----RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERET 218
RE++++ E+ RQ+E+ RE+ + R + E +E+E K ++ E+ E+E E +
Sbjct: 371 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ-EEKMWEQEEEMQ- 428
Query: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDK-------ERERERDRDRD 271
E E + +RQ ++ R++++K + EK E+E + + E+ E+E + +
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488
Query: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
+ RRQ+E+ R+ ++K + + E+ RE E + Q E+ E+E + E+ +E+E + +R
Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548
Query: 332 ETERDREKE---RERKRKRQ 348
+ E+ RE+E R+++ K Q
Sbjct: 549 QEEKMREQEVRLRQQEEKMQ 568
Score = 120 bits (301), Expect = 4e-27
Identities = 75/293 (25%), Positives = 159/293 (54%), Gaps = 14/293 (4%)
Query: 57 NRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQ 116
NR +++ + RQ E+ +R+ + + ++++ R+++ RQ + E+E + R+ +
Sbjct: 280 NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 339
Query: 117 REKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ 176
EKE ++ E+ E+E R Q + ++E E+ R+ EK +E++ RQ + R ++
Sbjct: 340 WEKEEKIRELEEKMHEQEKIR---EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 396
Query: 177 KE-REREKNRQERRERERQREK---ENKTEDRHSERGRERERERETETETERKRQTDRER 232
++ RE+E+ QE+ E+ ++E+ E + E + E R+ E+ E E + + Q ++ R
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIR 456
Query: 233 DRQRKTEREREKQAERE------RASERETERDKERERERDRDRDRD-RRQKERERQTDR 285
+++ + + EK E+E A +E E R+ E+ R++++ R Q+E+ R+ +
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Query: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDRE 338
Q + E+ E E K Q E+ +E+E +R+ E+ RE+E +++ E+ +E
Sbjct: 517 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 98.6 bits (244), Expect = 1e-20
Identities = 99/416 (23%), Positives = 192/416 (46%), Gaps = 35/416 (8%)
Query: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR-EK 119
+ ++++ T ET +D + +H+E R RE E + QT R Q+ E
Sbjct: 72 DTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALR-RELEAQVQTIRILTCQKTEL 130
Query: 120 ERNRQKERERETEREGERGRD---RQTDGQR---ERERQRDAEKERERQTDRERQRQTER 173
+ + + EGE RD R D + E E+ A ++++ DR + T+
Sbjct: 131 QMALYYSQHAVKQLEGE-ARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKE 189
Query: 174 NRQKEREREKNRQERRE-RERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
E +N E +E+ + + K + SE+ + +E + + ER + ++
Sbjct: 190 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 249
Query: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Q + + ++ + + E ++ R + ++ RQ+E+ ++ + K Q + E
Sbjct: 250 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEE 309
Query: 293 RDRETERKRERQRERERERERNRKRERERERERERERQRETER---DREKERERKRKRQT 349
+ RE E K RQ E E+E +R+ E E+E E+ RE E ++EK RE++ KRQ
Sbjct: 310 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKIRELEEKMHEQEKIREQEEKRQE 368
Query: 350 EMDRERNRQTGREGRRQAERERERERE----RDRQSAREREERERDRDRDRQKERERQTE 405
E + E+E+ +E+E R + RE+EE+ R+++ Q++ E+ E
Sbjct: 369 E-------------EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGE 415
Query: 406 -KDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
+++ ++E E Q + EK R E E+ RE+EK+ + ++ R+ + Q ++
Sbjct: 416 QEEKMWEQEEEMQEQEEKMRRQE---EKIREQEKKIREQEEKIREQEEMMQEQEEK 468
Score = 84.0 bits (206), Expect = 4e-16
Identities = 48/209 (22%), Positives = 114/209 (54%), Gaps = 13/209 (6%)
Query: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREK---ERERQ 108
+ E+ +++E+ R +EKRQ + ++E + + + R++ Q EK + E+
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 109 TDRERDRQREKER-NRQKERERETER----EGERGRDRQTDGQRERERQRDAEKERERQT 163
++E + Q ++E+ RQ+E+ RE E+ + E+ R+++ Q + E+ + E + Q
Sbjct: 421 WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER-----ERET 218
+ ++++ + RQ+E+ RE+ ++ R + E+ RE+E +++ + + E+ E+
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 540
Query: 219 ETETERKRQTDRERDRQRKTEREREKQAE 247
E E + +RQ ++ R+++ + ++ EK E
Sbjct: 541 EQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 63.2 bits (152), Expect = 7e-10
Identities = 36/159 (22%), Positives = 89/159 (55%), Gaps = 6/159 (3%)
Query: 42 LGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDR 101
+G+ + + E Q+E+ RR+E++ RE ++K + EK R ++ + ++
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEK--IREQEKKIREQEEKIREQEEMMQEQEEKMG 470
Query: 102 EKERERQTDRERDRQREKERNRQKERERETER----EGERGRDRQTDGQRERERQRDAEK 157
E+E + + +++E++ RQ+E+ RE E+ + E+ R+++ Q + E+ + E+
Sbjct: 471 EQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 530
Query: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196
+ Q ++ ++++ + RQ+E+ RE+ + R++ E+ +E
Sbjct: 531 KMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 35.4 bits (80), Expect = 0.15
Identities = 20/100 (20%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 32 GSQESPRRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREKDRHRK 90
G QE + + + R+ + +E+E++ RE+ + RE + + + EK ++
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 529
Query: 91 RDRHRERQRDREKERERQTDRERDRQREKERNRQKERERE 130
+ ++ +E+E + + E+ R++E +Q+E+ +E
Sbjct: 530 EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 32.3 bits (72), Expect = 1.3
Identities = 50/277 (18%), Positives = 112/277 (40%), Gaps = 15/277 (5%)
Query: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ-AERERA 251
++++ N T + G E E + + + RE + Q +T R Q E + A
Sbjct: 74 KKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMA 133
Query: 252 SERETERDKERERE-RD---RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER 307
K+ E E RD R D + E E+ ++ + DR E + +
Sbjct: 134 LYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDAL 193
Query: 308 ERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQA 367
E RN + E + + + +++ + EK + ++ + ER + + + QA
Sbjct: 194 SLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA 253
Query: 368 ERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESE 427
E + ++ QS + + + + + + ++Q EK +Q E+ ++RE +
Sbjct: 254 EADH---LGKELQSVSAKLQAQVEENELWNRLNQQQEEK-------MWRQEEKIQEREEK 303
Query: 428 RGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLY 464
+ + RE+++ R E +++ +R+ ++
Sbjct: 304 IQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 340
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 133 bits (335), Expect = 4e-31
Identities = 90/250 (36%), Positives = 131/250 (52%), Gaps = 25/250 (10%)
Query: 195 REKENKTEDRHSERGRERERERETET-ETERKRQTDRERD-RQRKTEREREKQAERERAS 252
R E KTE++ R + + R Q ++ER R++ ERERE + S
Sbjct: 1102 RPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRS 1161
Query: 253 ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER- 311
ERE +RDK RE R R R RDRR+KER + ++K +++ + E K R+ +
Sbjct: 1162 EREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAA 1221
Query: 312 ----------ERNRKRERER-ERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
+ ++E ER ER +ERE++R +E+E E +++R+ E +RERNRQ
Sbjct: 1222 PCIYWLPLTDSQIVQKEAERAERAKEREKRR-----KEQEEEEQKEREKEAERERNRQLE 1276
Query: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRER 420
RE RR+ RER+RERE RERE DRDRDR+++RER E+DR + + R R
Sbjct: 1277 REKRREHSRERDRERE------RERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSR 1330
Query: 421 EKDRESERGR 430
GR
Sbjct: 1331 STPVRDRGGR 1340
Score = 123 bits (309), Expect = 4e-28
Identities = 75/204 (36%), Positives = 123/204 (60%), Gaps = 23/204 (11%)
Query: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER 335
Q+E+ER R++ ER+RE ER+ + ERE +R++ R+ R R R R+R R++E +
Sbjct: 1135 QREQERAV---REQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDR-RRKERAK 1190
Query: 336 DREKERERKRKRQTEMDRERNRQTGREGRR---------------QAERER-ERERERDR 379
+EK+ E+K K Q E + R+ + Q E ER ER +ER++
Sbjct: 1191 SKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREK 1250
Query: 380 QSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERG-RERGREREK 438
+ + EE +++R+++ ++ER RQ E+++ + E+ RERE++RE +RG R+R RER++
Sbjct: 1251 RRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDR 1310
Query: 439 QKGRERDRERQTDRQAGRQRKRST 462
++GRERDR R T R + R R RST
Sbjct: 1311 ERGRERDR-RDTKRHS-RSRSRST 1332
Score = 117 bits (294), Expect = 2e-26
Identities = 77/212 (36%), Positives = 111/212 (52%), Gaps = 21/212 (9%)
Query: 191 RERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERER 250
R QRE+E ++ +ER RE ER T +E E R RE R R R+R ++ ER +
Sbjct: 1132 RAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRK-ERAK 1190
Query: 251 ASERETERDKERERERDRDRDRDRRQKER-----------ERQTDRKRQRRTERDRETER 299
+ E+++E+ ++ + E D +K + + Q +K R ER +E E+
Sbjct: 1191 SKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREK 1250
Query: 300 KRERQ-------RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
+R+ Q RE+E ERERNR+ ERE+ RE RER RE ER+RE++R R R E D
Sbjct: 1251 RRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDR-GDRDRDRERD 1309
Query: 353 RERNRQTGREGRRQAERERERERE-RDRQSAR 383
RER R+ R ++ R R R RDR R
Sbjct: 1310 RERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 117 bits (293), Expect = 3e-26
Identities = 77/223 (34%), Positives = 119/223 (53%), Gaps = 31/223 (13%)
Query: 95 RERQRDREKE-RERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
R QR++E+ RE+ +RER+ +R + ++E +R+ REG R R R D +R +ER +
Sbjct: 1132 RAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRD-RRRKERAK 1190
Query: 154 DAEKERERQTDRERQRQTERNRQKERERE----------------KNRQERRERERQREK 197
EK+ E++ + + + R+ + + ER ER ++REK
Sbjct: 1191 SKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREK 1250
Query: 198 ENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257
R E+ E ++ERE E E ER RQ +RE+ R+ ER+RE++ ERER +
Sbjct: 1251 ------RRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERER---DRGD 1301
Query: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTE-RDRETER 299
RD++RER+R+R R+RDRR +R R R R T RDR R
Sbjct: 1302 RDRDRERDRERGRERDRRDTKRH---SRSRSRSTPVRDRGGRR 1341
Score = 116 bits (291), Expect = 5e-26
Identities = 66/199 (33%), Positives = 114/199 (57%), Gaps = 22/199 (11%)
Query: 54 RERNRQKERE-RRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
RE+ ++ERE RRE+ ++ERE DR + R + R R RDR R+++R K +E++++++
Sbjct: 1143 REQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDR---RRKERAKSKEKKSEKK 1199
Query: 113 RDRQREKERNRQKERERET-----------------EREGERGRDRQTDGQRERERQRDA 155
Q E + R+T ++E ER + +R +E++ +
Sbjct: 1200 EKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEE 1259
Query: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE 215
+KERE++ +RER RQ ER +++E RE++R+ RERER R ++ +R ERGRER+R
Sbjct: 1260 QKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDR- 1318
Query: 216 RETETETERKRQTDRERDR 234
R+T+ + + ++ RDR
Sbjct: 1319 RDTKRHSRSRSRSTPVRDR 1337
Score = 115 bits (287), Expect = 2e-25
Identities = 79/221 (35%), Positives = 118/221 (53%), Gaps = 33/221 (14%)
Query: 170 QTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTD 229
Q R Q+E+ER Q ER+RE E + R ERE +R+ E R R
Sbjct: 1129 QHPRAEQREQERAVREQWA---EREREMERRERTR-----SEREWDRDKVREGPRSRSRS 1180
Query: 230 RERDRQRKTEREREKQAERERASERETER---DKERERER---------------DRDRD 271
R+R R+ + + + +K ++E+A E + D R+ + ++ +
Sbjct: 1181 RDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAE 1240
Query: 272 RDRRQKERE-RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER--- 327
R R KERE R+ +++ + + ER++E ER+R RQ ERE+ RE +R+R+RERERERER
Sbjct: 1241 RAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRG 1300
Query: 328 ERQRETERDREKERERKRKRQTEMDRERNRQT---GREGRR 365
+R R+ ERDRE+ RER R+ R R+R T R GRR
Sbjct: 1301 DRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 112 bits (280), Expect = 1e-24
Identities = 71/211 (33%), Positives = 116/211 (54%), Gaps = 24/211 (11%)
Query: 126 ERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNR 185
+ R +RE ER R+ +RERE +R ER+ DR++ R+ R+R + R+R +
Sbjct: 1129 QHPRAEQREQERAV-REQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKE 1187
Query: 186 QERRERERQREKENKTEDRHSERGRERERERE---------------TETETERKRQTDR 230
+ + + ++ +KE E+ ++ + R+ + + E ER + +
Sbjct: 1188 RAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERA-K 1246
Query: 231 ERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
ER+++RK E+E E+Q ERE+ +ERE R ERE+ R+ R+RD R++ERER+ D R
Sbjct: 1247 EREKRRK-EQEEEEQKEREKEAERERNRQLEREKRREHSRERD-RERERERERD-----R 1299
Query: 291 TERDRETERKRERQRERERERERNRKRERER 321
+RDR+ ER RER RER+R + R R R
Sbjct: 1300 GDRDRDRERDRERGRERDRRDTKRHSRSRSR 1330
Score = 90.9 bits (224), Expect = 3e-18
Identities = 57/190 (30%), Positives = 98/190 (51%), Gaps = 23/190 (12%)
Query: 39 RRGLGQAHKDADGD---DRERNRQKERERRREKR-QTERETDRKRERRREKDRHRKRDRH 94
RR ++ ++ D D + R+R + R+RRR++R +++ + K+E+ +E+ + D
Sbjct: 1155 RRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDL 1214
Query: 95 RERQR----------------DREKERERQTDRERDRQREKERNRQKERERETEREGERG 138
+ + +E ER + R++E+E QKERE+E ER ER
Sbjct: 1215 FRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAER--ERN 1272
Query: 139 RDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKE 198
R + + +RE R+RD E+ERER+ DR R +R R +ER RE++R++ + R R +
Sbjct: 1273 RQLEREKRREHSRERDRERERERERDR-GDRDRDRERDRERGRERDRRDTKRHSRSRSRS 1331
Query: 199 NKTEDRHSER 208
DR R
Sbjct: 1332 TPVRDRGGRR 1341
Score = 86.7 bits (213), Expect = 6e-17
Identities = 52/171 (30%), Positives = 87/171 (50%), Gaps = 14/171 (8%)
Query: 304 QRERERERERNRK-RERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGRE 362
Q R +RE+ R RE+ ERERE ER+ T +RE +R++ R+ R R+R+
Sbjct: 1129 QHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKER 1188
Query: 363 GRRQAERERERERERDRQSAREREERERDR-------------DRDRQKERERQTEKDRD 409
+ + ++ ++E+ ++ A+ ++ R + QKE ER
Sbjct: 1189 AKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKER 1248
Query: 410 GQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
+R E++ E +K+RE E RER R+ E++K RE RER +R+ R+R R
Sbjct: 1249 EKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDR 1299
Score = 67.8 bits (164), Expect = 3e-11
Identities = 111/522 (21%), Positives = 184/522 (35%), Gaps = 58/522 (11%)
Query: 59 QKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQRE 118
+K EK ++ E RK ERR + R + + E + E+E +++T R R
Sbjct: 204 RKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRA 263
Query: 119 KERNRQKERERETEREGERGRDRQTD--GQRERE---------------RQRDAEKERER 161
+ +E E E E E E + + D GQ+ RE R + E ER
Sbjct: 264 DRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDER 323
Query: 162 QTDRERQRQT-ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETET 220
R ++++ ER + R +E+ R+ R+ Q+EKE KT E RE + + +
Sbjct: 324 PKTRSQEQEVLERGGRFTRSQEEARKSHLARQ-QQEKEMKTTSPLEEEEREIKSSQGLKE 382
Query: 221 ET----------ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD--- 267
++ +RK+ + Q +E E + AS E E +
Sbjct: 383 KSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPME 442
Query: 268 ------------RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR 315
+ D D R+ + T + + ++ K E E+ E
Sbjct: 443 GPAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLP 502
Query: 316 KRERERERERERERQRETERDREK-------ERERKRKRQTEMDRERNRQTGREGRRQAE 368
++ + ++ E E DR E K TE ++ +EGRR +
Sbjct: 503 LVQKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASH 562
Query: 369 RERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESER 428
R +QSA R + R R D G R R +++D R
Sbjct: 563 TLLPSHRL--KQSADSSSSRSSSSSSSSSRSRSR--SPDSSGSRSHSPLRSKQRDVAQAR 618
Query: 429 GRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGI 488
R R K R R R R ++ P + S ++ P+ G
Sbjct: 619 THANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSG- 677
Query: 489 RWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEK 530
+ ++P P+ P R + +S V RR +P EK
Sbjct: 678 QEVATPPVPQLQVCE-PKERTSTSS-SSVQARRLSQPESAEK 717
Score = 66.6 bits (161), Expect = 6e-11
Identities = 77/302 (25%), Positives = 128/302 (42%), Gaps = 28/302 (9%)
Query: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER- 232
N Q E +N ++ E+Q+E + +R + E E E E+E E
Sbjct: 124 NSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELE-EASAESEDEMIHPEGVASL 182
Query: 233 ---DRQRKTER---EREKQAERERASERETERDKERERERDRDRDRDR-RQKERERQTDR 285
D Q ER E + + R+ +S E + D + E+ R +R R RQ + ++
Sbjct: 183 LPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEG 242
Query: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
+ E D+ET + R R +RN K E E E E E E E + + E + E ++
Sbjct: 243 SQPAEEEEDQETPSRNLRVRA-----DRNLKTEEEEEEEEEEE---EDDEEEEGDDEGQK 294
Query: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTE 405
R+ + +E ++ G E R E ER + R ++E+E ER R +E R++
Sbjct: 295 SREAPILKE-FKEEGEEIPRVKPEEMMDERPKTR--SQEQEVLERGGRFTRSQEEARKSH 351
Query: 406 KDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYV 465
R Q EK+ + E E + + K+K + R T+ RK+++L
Sbjct: 352 LARQQQ---EKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTE-----DRKKASLVA 403
Query: 466 NP 467
P
Sbjct: 404 LP 405
Score = 58.9 bits (141), Expect = 1e-08
Identities = 50/225 (22%), Positives = 99/225 (44%), Gaps = 18/225 (8%)
Query: 84 EKDRH--RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDR 141
E RH RK E + D + E+ R+ +R R R+ + E + E E D+
Sbjct: 197 ELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEE----EDQ 252
Query: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN-- 199
+T + R R K E + + E + + + + + E +K+R+ +E + E E
Sbjct: 253 ETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIP 312
Query: 200 --KTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257
K E+ ER + R +E+E ER + R ++ RK+ R++Q + + + E
Sbjct: 313 RVKPEEMMDERPKTRSQEQEV---LERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEE 369
Query: 258 RDKERE-----RERDRDRDRDRRQKERERQTDRKRQRRTERDRET 297
++E + +E+ + R ++R++ + +T + ET
Sbjct: 370 EEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEET 414
Score = 58.5 bits (140), Expect = 2e-08
Identities = 64/281 (22%), Positives = 112/281 (39%), Gaps = 27/281 (9%)
Query: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEK---ERERQ 162
E+Q + R R + R + E E E E + Q E+ E R
Sbjct: 142 EKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQSSLERPELELSRH 201
Query: 163 TDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETET 222
+ R+ +E + E+ + + R R RQ +E + E E ++ET +
Sbjct: 202 SPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSE---GSQPAEEEEDQETPSRN 258
Query: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
R R DR KTE E E++ E E E E E D E ++ R+ ++ +++ E
Sbjct: 259 LRVRA-----DRNLKTEEEEEEEEEEEEDDEEE-EGDDEGQKSREAPILKEFKEEGEE-- 310
Query: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342
R + E ER + R +E+E ER R +E R++ R+ ++E
Sbjct: 311 --------IPRVKPEEMMDERPKTRSQEQE---VLERGGRFTRSQEEARKSHLARQ-QQE 358
Query: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERER-ERDRQSA 382
++ K + ++ E +G ++ + R DR+ A
Sbjct: 359 KEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKA 399
Score = 56.6 bits (135), Expect = 6e-08
Identities = 57/261 (21%), Positives = 107/261 (40%), Gaps = 13/261 (4%)
Query: 97 RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDR-QTDGQRERERQRDA 155
RQR + RE E + E E + + + +R + + R R+ +
Sbjct: 149 RQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSS 208
Query: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE 215
E + +D E+ R+ ER + R+ + + + E++ +T R+ +R +
Sbjct: 209 ISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLK 268
Query: 216 RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRR 275
E E E E + + D E + E + E Q RE +E + + E + D R
Sbjct: 269 TEEEEEEEEEEEEDDEEE-----EGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDER 323
Query: 276 QKERERQTD-RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETE 334
K R ++ + +R R R +E RK R+++ + + E ERE + ++
Sbjct: 324 PKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEERE-----IKSSQ 378
Query: 335 RDREKERERKRKRQTEMDRER 355
+EK + R TE DR++
Sbjct: 379 GLKEKSKSPSPPRLTE-DRKK 398
Score = 52.4 bits (124), Expect = 1e-06
Identities = 41/191 (21%), Positives = 76/191 (39%), Gaps = 2/191 (1%)
Query: 72 ERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERET 131
E E R R+ K D E+ R E+ R + E + ++E ++ET
Sbjct: 195 ELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQET 254
Query: 132 EREGERGRDRQTDGQRERERQRDAEKE--RERQTDRERQRQTERNRQKEREREKNRQERR 189
R R + E E + + E+E E + D E Q+ E KE + E R
Sbjct: 255 PSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRV 314
Query: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249
+ E ++ KT + E R ++ E + ++++++ KT E++
Sbjct: 315 KPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREI 374
Query: 250 RASERETERDK 260
++S+ E+ K
Sbjct: 375 KSSQGLKEKSK 385
Score = 48.9 bits (115), Expect = 1e-05
Identities = 24/66 (36%), Positives = 37/66 (56%)
Query: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
+E+ R R + RER+R++ERER R++ +R+ +R RER RE+DR +
Sbjct: 1265 KEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKRH 1324
Query: 94 HRERQR 99
R R R
Sbjct: 1325 SRSRSR 1330
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
+ R E R R L + + +R+R R++ERER R R +RE DR+R R R++
Sbjct: 1261 KEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRD 1320
Query: 88 HRKRDRHRERQ---RDREKER 105
++ R R R RDR R
Sbjct: 1321 TKRHSRSRSRSTPVRDRGGRR 1341
Score = 46.6 bits (109), Expect = 7e-05
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 7/121 (5%)
Query: 368 ERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD-RES 426
+ R +RE++R + ERER+ +R + ER E DRD RE + R R +D R
Sbjct: 1129 QHPRAEQREQERAVREQWAEREREMERRERTRSER--EWDRDKVREGPRSRSRSRDRRRK 1186
Query: 427 ERGRERGRERE-KQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPT 485
ER + + ++ E K+K +E + D + + +Y P S +VQ + R
Sbjct: 1187 ERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLP---LTDSQIVQKEAERAE 1243
Query: 486 R 486
R
Sbjct: 1244 R 1244
Score = 39.7 bits (91), Expect = 0.008
Identities = 43/238 (18%), Positives = 72/238 (30%), Gaps = 9/238 (3%)
Query: 59 QKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQRE 118
QKE R + + + R R R + R R +QR+
Sbjct: 554 QKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRD 613
Query: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
+ R R + G R R R R + + R T K+
Sbjct: 614 VAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKD 673
Query: 179 RE--REKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
+E + + KE + S + R + E ++ Q +R ++
Sbjct: 674 PSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPKKC 733
Query: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294
+ E A + + SE +T E ER +E+E T + R E D
Sbjct: 734 EAEEAEPPAATQPQTSETQTSHLPESERIH-------HTVEEKEEVTMDTSENRPEND 784
Score = 39.3 bits (90), Expect = 0.010
Identities = 63/378 (16%), Positives = 125/378 (33%), Gaps = 37/378 (9%)
Query: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDR 165
++ D R + + R R + G R QR+ + R R R
Sbjct: 571 KQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMG 630
Query: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENK---TEDRHSERGRE----------- 211
R R+R + R R + R+ +++ TE + G+E
Sbjct: 631 SRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQV 690
Query: 212 ---RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDR 268
+ER + + + +R + E + T+R + ++ ++ E E + +
Sbjct: 691 CEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSE 750
Query: 269 DRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERE 328
+ + ER T +++ T D R E + E E E
Sbjct: 751 TQTSHLPESERIHHTVEEKEEVT-MDTSENRPENDVPEPPMPIADQVSNDDRPEGSVEDE 809
Query: 329 RQRETERDREKERERKRKRQTEMDRERNRQT--GREGR-RQAERERERERERDRQSARER 385
++E+ + +R+ T+ N T G+ GR R+ +++ S
Sbjct: 810 EKKESSLPKSFKRKISVVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTE 869
Query: 386 EERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESE----------------RG 429
+ D +E + D R +E + ER D + G
Sbjct: 870 SLKSLIPDIKPLAGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEG 929
Query: 430 RERGREREKQKGRERDRE 447
+E G+ E+++ +E + E
Sbjct: 930 QENGQREEEEEEKEPEAE 947
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 130 bits (328), Expect = 3e-30
Identities = 109/398 (27%), Positives = 199/398 (50%), Gaps = 47/398 (11%)
Query: 52 DDRERNRQKERERRREKRQTERETDRKRERR----REKDRHRKRDRHRERQRDREKERER 107
D ++R+ +E R+ R +RE DR R+R+ +++ RHR RDR R R R + R +
Sbjct: 7 DKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSK 66
Query: 108 QTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRER 167
+RER R KER R KER+R ++ RDR DG R +K+R+R +
Sbjct: 67 SAERER---RHKERERDKERDR-----NKKDRDRDKDGHRR-------DKDRKRSSLSPG 111
Query: 168 QRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQ 227
+ + ++R K+R+ +K+ ++ ++ + + E+ +++ E E E + + ++ +R+
Sbjct: 112 RGKDFKSR-KDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAERE 170
Query: 228 TDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKR 287
+ + RQ++ E ER++ E ER K+R++ +D R +ERER+ R+R
Sbjct: 171 AEALKRRQQEVE-ERQRMLEEER---------KKRKQFQDLGRKMLEDPQERERRERRER 220
Query: 288 QRRTERDRETERKRERQR-ERERERERNRKRERERERERERERQRETERDREKERERKRK 346
R E E R++ R E+++ +E + +ER ++R R R DR+ E
Sbjct: 221 MERETNGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHL-NDRKFVFEWDAS 279
Query: 347 RQTEMD-----RERNRQTGREGR--------RQAERERERERERDRQSAREREERERDRD 393
T +D +ER+ Q GR +Q +RE+ R + R EE+E++
Sbjct: 280 EDTSIDYNPLYKERH-QVQLLGRGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEA 338
Query: 394 RDRQKERERQTEKDRDGQRETEKQREREKDRESERGRE 431
R R K R+++ ++ D + ++K+ + DR+ RE
Sbjct: 339 RLR-KLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFRE 375
Score = 119 bits (297), Expect = 1e-26
Identities = 83/275 (30%), Positives = 139/275 (50%), Gaps = 25/275 (9%)
Query: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR 204
G+ ++ RDA +E +R+R R +R R ++R+R+ + + R+R R R++ R
Sbjct: 3 GELADKKDRDASPSKE---ERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRR-----R 54
Query: 205 HSERGRERERERETETETERK-RQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
R R R R + E E K R+ D+ERDR +K +R+R+K R + + R
Sbjct: 55 GGSRSRSRSRSKSAERERRHKERERDKERDRNKK-DRDRDKDGHRRDKDRKRSSLSPGRG 113
Query: 264 RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER 323
++ +DRD ++ E + D+K + + E K++ + E E + + K ERE E
Sbjct: 114 KDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEA 173
Query: 324 ERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAR 383
+ R+++ E ER R E ERK+++Q + GR+ E +ERER R+R+
Sbjct: 174 LKRRQQEVE-ERQRMLEEERKKRKQFQ----------DLGRKMLEDPQERER-RERRERM 221
Query: 384 EREERERDRDRDRQKERERQTEKDRDGQRETEKQR 418
ERE + + RQK RE EKD+ + K+R
Sbjct: 222 ERETNGNEDEEGRQKIRE---EKDKSKELHAIKER 253
Score = 104 bits (260), Expect = 2e-22
Identities = 68/260 (26%), Positives = 133/260 (51%), Gaps = 18/260 (6%)
Query: 218 TETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQK 277
++ E +R R DRERDR R + K +R R+ +R + R R R + +R+RR K
Sbjct: 16 SKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHK 75
Query: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDR 337
ERER +R R ++ +RDR+ + R R+++R+R+ R ++ + + R++++D
Sbjct: 76 ERERDKERDRNKK-DRDRDKDGHR-----RDKDRKRS-SLSPGRGKDFKSRKDRDSKKDE 128
Query: 338 EKER-ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396
E E ++K K Q E + E +A+ + + ER+ ++ + R++ +R R
Sbjct: 129 EDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRML 188
Query: 397 QKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQ--- 453
++ER+++ + G++ E +ERE+ ER E ++GR++ RE + +
Sbjct: 189 EEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKELH 248
Query: 454 -------AGRQRKRSTLYVN 466
G +++R T ++N
Sbjct: 249 AIKERYLGGIKKRRRTRHLN 268
Score = 104 bits (259), Expect = 3e-22
Identities = 92/355 (25%), Positives = 169/355 (47%), Gaps = 35/355 (9%)
Query: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK-RQTERETDRKRERR-REKDR 87
R S+ R R + K + DR+R+R ++R R + R R +RERR +E++R
Sbjct: 20 RKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERER 79
Query: 88 HRKRDRHRERQRDREKERERQTDRERDRQ-----REKERNRQKERERETEREGERGRDRQ 142
++RDR++ + RDR+K+ R+ D++R R R K+ +K+R+ + + E E G D++
Sbjct: 80 DKERDRNK-KDRDRDKDGHRR-DKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHG-DKK 136
Query: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202
Q + A+K+ E + + + + ++ R+ E ++ +QE ER+R E+E K
Sbjct: 137 PKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAE-ALKRRQQEVEERQRMLEEERKKR 195
Query: 203 DRHSERGR-------ERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255
+ + GR ERER RE ER+ + + + ++K E++K E ER
Sbjct: 196 KQFQDLGRKMLEDPQERER-RERRERMERETNGNEDEEGRQKIREEKDKSKELHAIKERY 254
Query: 256 TERDKERERER---------------DRDRDRDRRQKERERQTDRKRQRRTERDRETERK 300
K+R R R D D + KER + R D + +++
Sbjct: 255 LGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRGFIAGIDLKQQKR 314
Query: 301 RERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEM-DRE 354
+ + + +R E+E+E R R+ +++ + R +R +K+ EM DR+
Sbjct: 315 EQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRD 369
Score = 90.5 bits (223), Expect = 4e-18
Identities = 75/243 (30%), Positives = 125/243 (51%), Gaps = 39/243 (16%)
Query: 249 ERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERE 308
E A +++ + +E ER R R DR ER+R DR R+ +DR+ R R+R+R
Sbjct: 4 ELADKKDRDASPSKE-ERKRSRTPDR---ERDR--DRDRKSSPSKDRKRHRSRDRRRGGS 57
Query: 309 RERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR-RQA 367
R R R+R + ERER R +ER+R+ ERDR K+ + K D++R R + GR +
Sbjct: 58 RSRSRSRSKSAERER-RHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDF 116
Query: 368 ERERERERERDRQS------------------AREREERERDRDRDRQKERERQTEKDRD 409
+ ++R+ ++D + A+++ E E + + ER+ E +
Sbjct: 117 KSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKR 176
Query: 410 GQRET-EKQREREKDRESER-----GR---ERGREREKQKGRERDRERQT---DRQAGRQ 457
Q+E E+QR E++R+ + GR E +ERE+++ RER ER+T + + GRQ
Sbjct: 177 RQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRER-MERETNGNEDEEGRQ 235
Query: 458 RKR 460
+ R
Sbjct: 236 KIR 238
Score = 81.6 bits (200), Expect = 2e-15
Identities = 51/175 (29%), Positives = 91/175 (52%), Gaps = 16/175 (9%)
Query: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER 355
E K++R +E ER R R +RER+R+R+R+ +DR++ R R R+R R R
Sbjct: 4 ELADKKDRDASPSKE-ERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSR 62
Query: 356 NRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETE 415
+R + AERER R +ER+R R+R +++RDRD+D + +KDR + +
Sbjct: 63 SRS------KSAERER-RHKERERDKERDRNKKDRDRDKDGHRR-----DKDR---KRSS 107
Query: 416 KQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPR 470
R KD +S + R+ ++ E + G ++ + + + +K++ P+
Sbjct: 108 LSPGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPK 162
Score = 61.6 bits (148), Expect = 2e-09
Identities = 37/107 (34%), Positives = 60/107 (56%), Gaps = 7/107 (6%)
Query: 363 GRRQAERERERERERDRQSAREREERERDRDRDRQ----KERERQTEKDRDGQRETEKQR 418
G +++R+ ++ + +RERDRDRDR+ K+R+R +DR + R
Sbjct: 3 GELADKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSR 62
Query: 419 EREKDRESERGRERGREREKQKGR-ERDRERQTD-RQAGRQRKRSTL 463
R K E ER R + RER+K++ R ++DR+R D + + RKRS+L
Sbjct: 63 SRSKSAERER-RHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSL 108
Score = 44.3 bits (103), Expect = 3e-04
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Query: 401 ERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
E +KDRD E ER++ R +R R+R R+R+ ++R R R DR+ G R R
Sbjct: 4 ELADKKDRDASPSKE---ERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSR 60
Query: 461 STLYVNPPPRTARSGVVQSDPNR 483
S R R + D R
Sbjct: 61 SRSRSKSAERERRHKERERDKER 83
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 129 bits (323), Expect = 1e-29
Identities = 82/328 (25%), Positives = 142/328 (43%), Gaps = 37/328 (11%)
Query: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETE 219
E + R+R R+R R R ++R R+ R R ++ HS + R R R
Sbjct: 174 EDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRS----GSSKSSHS-KSRSRSRSGSRS 228
Query: 220 TETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKER 279
R R R R ++ K+ R K+ R R+ R K +++ ++ ++ D K +
Sbjct: 229 RSKSRSRSQSRSRSKKEKS-RSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPK 287
Query: 280 ERQTDRKRQRRTERDRETERKRERQRE----RERERERNRKRERERERERERERQRETER 335
R R + + R R ER+ E ++ R R +E++ ++ R R R + R R R
Sbjct: 288 SRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
+ K++ + RKR E R R+R R ++ER R+R +RD ++ +++++ D DR
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRS-----RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS 402
Query: 396 RQKERERQTEKDRDGQRETEKQRE--------------REKDRESERG--------RERG 433
+ + R K+R+ + QRE R + R + + R R
Sbjct: 403 QSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRS 462
Query: 434 REREKQKGRERDRERQTDRQAGRQRKRS 461
+ K + R + R R R R R RS
Sbjct: 463 KSASKTRSRSKSRSRSASRSPSRSRSRS 490
Score = 128 bits (321), Expect = 2e-29
Identities = 79/311 (25%), Positives = 123/311 (39%), Gaps = 10/311 (3%)
Query: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETER-EG 135
R R R R R R RH + R R + + R R R R+R K R R R
Sbjct: 183 RSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRS 242
Query: 136 ERGRDRQTDGQRERERQRDAEKERERQTDR-ERQRQTERNRQKEREREKNRQERRERERQ 194
++ + R ++ R R A K R + D+ E + Q N K + R +R + + + R
Sbjct: 243 KKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRS 302
Query: 195 REKENKTEDRHS---ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERA 251
R +E + E+ RGR +E+ R + R R R R +++ K +R R
Sbjct: 303 RSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSRE 362
Query: 252 SERETERDKER-ERERDRDRDRDRR----QKERERQTDRKRQRRTERDRETERKRERQRE 306
R R + + ER R R RD + +K+++ TDR + R R ER+ +
Sbjct: 363 ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES 422
Query: 307 RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQ 366
+RE + + R R R + R R + R R++ R R
Sbjct: 423 SQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRS 482
Query: 367 AERERERERER 377
R R R R
Sbjct: 483 PSRSRSRSHSR 493
Score = 127 bits (318), Expect = 4e-29
Identities = 84/363 (23%), Positives = 147/363 (40%), Gaps = 23/363 (6%)
Query: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
+ + +R EK + + + R E + ++ R R R R R ++ R R
Sbjct: 150 YSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSG 209
Query: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
++ + R R R R+R K R R ++R ++ + + + K+ R G+ R
Sbjct: 210 SSKSSHSKS--RSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS 267
Query: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273
+ ++ + E + + + + + R R + K R R+ ER E +K R R +++
Sbjct: 268 KSKD-QAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKS 326
Query: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333
RQ R R + R R R R + +++ + RKR RE R R R R +
Sbjct: 327 LRQS-----------RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS- 374
Query: 334 ERDREKERERKRKRQTE---MDRERNRQTGREGRRQAERERERERERDRQSAREREER-E 389
E+ R+R KR ++ +++ T R R R +ERE + + +RE R E
Sbjct: 375 ----ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
Query: 390 RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQ 449
+ Q+ R R + + R R K R R + R R + R R R
Sbjct: 431 SENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRS 490
Query: 450 TDR 452
R
Sbjct: 491 HSR 493
Score = 124 bits (311), Expect = 2e-28
Identities = 81/350 (23%), Positives = 144/350 (41%), Gaps = 22/350 (6%)
Query: 61 ERERRREKRQTERETDRKRERRREKDRHRKR---DRHRERQRDREKERERQTDRERDRQR 117
+ +R EK RK +K R+R R R R R + R + R R
Sbjct: 152 DMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSS 211
Query: 118 EKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQK 177
+ ++ + R R R + R R R ++KE+ R +E+ R + K
Sbjct: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRSR-------SKKEKSRSPSKEKSRSRSHSAGK 264
Query: 178 EREREKNRQERR--ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQ 235
R + K++ E + + + ++++ RH + + R R +E E E++ R R ++
Sbjct: 265 SRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQE 324
Query: 236 R----KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKR-QRR 290
+ R R K R R+ R +DK + R+R R+ R R + + + RKR +R
Sbjct: 325 KSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKR 384
Query: 291 TERDRETERKRERQRERERERERNRKRERERERERERERQRETERDRE----KERERKRK 346
+ +++K++ +R + R +R +ERE + QRE + E + R R
Sbjct: 385 DSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS 444
Query: 347 RQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396
R + R + A + R R + R R ++R R R R R
Sbjct: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRS-PSRSRSRSHSR 493
Score = 119 bits (297), Expect = 1e-26
Identities = 74/316 (23%), Positives = 138/316 (43%), Gaps = 29/316 (9%)
Query: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
SR R S+ S + R + K + R R+R R R + + +++ + K+E+ R
Sbjct: 192 SRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPS 251
Query: 87 RHRKRDRHRERQRDREKERERQTDR---------------ERDRQREKERNRQKERERET 131
+ + R R + R K +++ ++ R + + K R+R +ER E
Sbjct: 252 KEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEE 311
Query: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER 191
E+ G R R +E+ ++ + R + R R R +++ K + R+++R+E R R
Sbjct: 312 EKRGSVSRGR----SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSR 367
Query: 192 ERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERA 251
R R K SER R+R +R+++ + +K++ + + DR + R ERE A
Sbjct: 368 SRSRSK--------SERSRKRGSKRDSKAGSSKKKKKE-DTDRSQSRSPSRSVSKEREHA 418
Query: 252 SERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER 311
++R+ E E + +++ R + R + R R + R R + R R
Sbjct: 419 KSESSQREGRGESE-NAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSR 477
Query: 312 ERNRKRERERERERER 327
+R R R R R
Sbjct: 478 SASRSPSRSRSRSHSR 493
Score = 113 bits (282), Expect = 6e-25
Identities = 79/339 (23%), Positives = 137/339 (40%), Gaps = 8/339 (2%)
Query: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
E+ TE N +K R E RR R R + + + R R + R R +++
Sbjct: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSH-SRSRSRSRHSRKSRSRSGSSKSSHS 216
Query: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
+ R R R + R + R R S++E R +E+ R R + + + + Q +
Sbjct: 217 KSRSRSRSGSRSRSKSRSRSQSRSR-SKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEE 275
Query: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
K Q + + R R + + ++R R +ER E E+ R +EK + R
Sbjct: 276 KIQNNDN----VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSR 331
Query: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTE 405
R R+R R + + R+R RE R +R R + ER R R +++ + +
Sbjct: 332 SRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSS 391
Query: 406 KDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYV 465
K + + +T++ + R R + RE + Q+ + E Q R R RS
Sbjct: 392 KKKK-KEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKS 450
Query: 466 NPP-PRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTR 503
P P +RS + R R +S+ P + +R
Sbjct: 451 KPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSR 489
Score = 110 bits (276), Expect = 3e-24
Identities = 94/418 (22%), Positives = 162/418 (38%), Gaps = 29/418 (6%)
Query: 126 ERERETEREGERGRDRQTDGQRERERQRDAEKERE--RQTDRERQRQTERNRQKEREREK 183
E R R+G G R G R R + R R + K+ R+
Sbjct: 68 EHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQA 127
Query: 184 NRQERRERERQREKENKTED-RHSERGRERERERETETE------------TERKRQTDR 230
+ + R+ E E +S+ R E+ TE + R+R R
Sbjct: 128 GEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSR 187
Query: 231 ERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR 290
R R R R + R R+ ++ K R R R R R K R R R R ++
Sbjct: 188 SRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRS---KSRSRSQSRSRSKK 244
Query: 291 TERDRETERKRERQRERERERERNRKRERERERERERE-----RQRETERDREKERERKR 345
E+ R +++ R R + R++ +++ E+ + + + R R + K + R R
Sbjct: 245 -EKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSR 303
Query: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTE 405
++ ++ E+ R ++ + R R R + +R R R R + +D++K R+R E
Sbjct: 304 SQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRS-RSRSKSKDKRKGRKRSRE 362
Query: 406 KDRDGQRETEKQREREKDRESERGRERGREREKQK-GRERDRERQTDRQAGRQRKRSTLY 464
+ R R K ER + R S+R + G ++K+K +R + R R ++R+ +
Sbjct: 363 ESRSRSRSRSKS-ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK-- 419
Query: 465 VNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRR 522
R R + N+ TR +S P S + A +R R R R
Sbjct: 420 SESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSR 477
Score = 50.8 bits (120), Expect = 3e-06
Identities = 29/153 (18%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Query: 27 SRRRPGSQESPRRRGLGQAHKDADGDDR-----ERNRQKERERRREKRQTERETDRKRER 81
SR R S+ +R+G ++ +++ R ER+R++ +R + ++++ +R
Sbjct: 342 SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDR 401
Query: 82 RREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDR 141
+ + R + RE + +RE + + E ++ R+R + + R R
Sbjct: 402 SQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSR 461
Query: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERN 174
+ R R + + R R R R R+
Sbjct: 462 SKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 128 bits (322), Expect = 1e-29
Identities = 76/271 (28%), Positives = 136/271 (50%), Gaps = 19/271 (7%)
Query: 140 DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN 199
D + DG + D +K++E+ R ++ + + R R RER+R+ +N
Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRS--------RERKRKSDN 56
Query: 200 KTEDRHSERGRERE-RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER 258
+ +H R R +E R E++ ++ +K +++ D++ +++ RE+ E +R +
Sbjct: 57 EGR-KHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRK 115
Query: 259 DKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRE 318
+++ R R R R R ++ R R +RK+ R R+R+ R R R+R++ R R R RKR
Sbjct: 116 ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRR 175
Query: 319 -RERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR-------EGRRQAERE 370
R R R R R R R R R + R R RK++ E R +R R GR A
Sbjct: 176 IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDA 235
Query: 371 RERERERDRQSAREREERERDRDRDRQKERE 401
+E R ++ + +E+RE++ ++QK++E
Sbjct: 236 QEALARRLERAKKLQEQREKEM-VEKQKQQE 265
Score = 125 bits (314), Expect = 1e-28
Identities = 76/275 (27%), Positives = 132/275 (48%), Gaps = 25/275 (9%)
Query: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
+TER+G D +++E+ + R + R R +R +ER+R+ + + R+
Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSR----SRSRERKRKSDNEGRK 60
Query: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249
R R R KE + RH + + ++ + +E +++ +D+ R+R +E ++ +E
Sbjct: 61 HRSRSRSKEGR---RHESKDKSSKKHK-SEEHNDKEHSSDKGRERLNSSENGEDRHKRKE 116
Query: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309
R S R R R R R+R R + RER+ R R R ++ R R+R++ R R R
Sbjct: 117 RKSSRG------RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
Query: 310 ERE-----RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE------RNRQ 358
ER+ R+R R R R R R R R R RDR+K E+ R+ + R R R
Sbjct: 171 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRN 230
Query: 359 TGREGRRQAERERERERERDRQSAREREERERDRD 393
T + + R ER ++ Q +E E+++ ++
Sbjct: 231 TAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
Score = 124 bits (312), Expect = 2e-28
Identities = 76/275 (27%), Positives = 133/275 (48%), Gaps = 17/275 (6%)
Query: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR-HSER 208
+ +RD + DR+++++ R + + R R R+R++++ E R H R
Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
Query: 209 GRERE-RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
R +E R E++ ++ +K +++ D++ +++ RE+ E +R ++++ R R
Sbjct: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
Query: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE- 326
R R R ++ R R +RK+ R R RER++ R R RER + R R RER+R
Sbjct: 125 HSRSRSRERRHRSRSRERKKSR--------SRSRERKKSRSRSRERKKSRSRSRERKRRI 176
Query: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
R R R R R + R R R R DR++ + R R R R R +A + +
Sbjct: 177 RSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQ 236
Query: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQRERE 421
E R +R K+ + Q EK+ EKQ+++E
Sbjct: 237 E-ALARRLERAKKLQEQREKEM-----VEKQKQQE 265
Score = 124 bits (310), Expect = 3e-28
Identities = 78/274 (28%), Positives = 130/274 (47%), Gaps = 24/274 (8%)
Query: 178 EREREKNRQERRERERQREKEN-------KTEDRHSERGRERERERETETETERKRQTDR 230
+ ER+ E+ +R ++KE + H R R R RER+ +++ E ++ R
Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
Query: 231 ERDRQRKTEREREKQAERERASE---RETERDKERERERDRDRDRDRRQKERERQTDRKR 287
R ++ + ++K +++ ++ E +E DK RER + DR +++
Sbjct: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRH---------KRK 115
Query: 288 QRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
+R++ R R R R R+R R R R R RK+ R R RER++ R R ER + + R R+RKR
Sbjct: 116 ERKSSRGRSHSRSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 174
Query: 348 QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREER-ERDRDRDRQKERERQTEK 406
+ R R+R R R R R R R RDR+ E+ R R R R
Sbjct: 175 RI---RSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 231
Query: 407 DRDGQRETEKQREREKDRESERGRERGREREKQK 440
D Q ++ ER K + +R +E ++++Q+
Sbjct: 232 AMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
Score = 121 bits (304), Expect = 2e-27
Identities = 79/256 (30%), Positives = 124/256 (48%), Gaps = 17/256 (6%)
Query: 100 DREKERERQ----TDRERDRQREKERNRQKERERETEREG--ERGRDRQTDGQRERERQR 153
DR+K++E+ + R + R+R +ER+R+++ EG R R R +G+R + +
Sbjct: 19 DRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDK 78
Query: 154 DAEKER-ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRER 212
++K + E D+E R R E ++R +R+ER+ R R R R R
Sbjct: 79 SSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR-------GRSHSRSRSR 131
Query: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272
ER R ERK+ R R+R++ R RE++ R R+ ER+ R + R R R R R R
Sbjct: 132 ER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERK-RRIRSRSRSRSRHRHR 189
Query: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE 332
R + R R R R++R E+ R R R R RN + + R ER ++
Sbjct: 190 -TRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKK 248
Query: 333 TERDREKERERKRKRQ 348
+ REKE K+K+Q
Sbjct: 249 LQEQREKEMVEKQKQQ 264
Score = 117 bits (292), Expect = 4e-26
Identities = 74/270 (27%), Positives = 125/270 (46%), Gaps = 17/270 (6%)
Query: 39 RRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQ 98
R GL D D ++ + R K R R RER+R+ D ++ HR R
Sbjct: 8 RDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK--HRSRS 65
Query: 99 RDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKE 158
R +E R D+ + + +E N + E ++GR+R + +R + E++
Sbjct: 66 RSKEGRRHESKDKSSKKHKSEEHN-------DKEHSSDKGRERLNSSENGEDRHKRKERK 118
Query: 159 RERQTDRERQRQTE-RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE 217
R R R E R+R + RER+K+R RER++ R +++ +R R R RER+R
Sbjct: 119 SSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR---SRSRERKKSRSRSRERKRR 175
Query: 218 TETET---ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR 274
+ + R R R R R R R+R+K+ E+ R R R R R+ D
Sbjct: 176 IRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMD- 234
Query: 275 RQKERERQTDRKRQRRTERDRETERKRERQ 304
Q+ R+ +R ++ + +R++E K+++Q
Sbjct: 235 AQEALARRLERAKKLQEQREKEMVEKQKQQ 264
Score = 115 bits (288), Expect = 1e-25
Identities = 69/241 (28%), Positives = 117/241 (48%), Gaps = 7/241 (2%)
Query: 211 ERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDR 270
+R++++E + R + R R RER+++++ E R R KE R +D+
Sbjct: 19 DRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDK 78
Query: 271 DRDRRQKE----RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326
+ + E +E +D+ R+R + +R + ++R+ R R +R R RER R R
Sbjct: 79 SSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER-RHRS 137
Query: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
R R+R+ R R +ER++ R R E + R+R R+ RR R R R R R R +R R
Sbjct: 138 RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERK-RRIRSRSRSRSRHRHRTRSRSR- 195
Query: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDR 446
R R RDR ++ E+ R+ + R R +++ R ER K+ +R++
Sbjct: 196 TRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREK 255
Query: 447 E 447
E
Sbjct: 256 E 256
Score = 112 bits (279), Expect = 1e-24
Identities = 73/246 (29%), Positives = 117/246 (47%), Gaps = 15/246 (6%)
Query: 228 TDRERD--RQRKTEREREKQAERE------RASERETERDKERERERDRDRDRDRRQKER 279
+D ERD KT +R+K+ E+ RAS+ R + R RER R D + R K R
Sbjct: 4 SDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGR-KHR 62
Query: 280 ERQTDRKRQRRTERDRETER-KRERQRERERERERNRKR--ERERERERERERQRETERD 336
R ++ +R +D+ +++ K E ++E ++ R+R E +R + ++R++ R
Sbjct: 63 SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 122
Query: 337 REKERERKR-KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
R R R R +R RER + R R+ R R RER++ R +RER+ R R R R
Sbjct: 123 RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS 182
Query: 396 RQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRE--RDRERQTDRQ 453
R + R R + R R ++++ EK R R R +GR D + R+
Sbjct: 183 RSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARR 242
Query: 454 AGRQRK 459
R +K
Sbjct: 243 LERAKK 248
Score = 108 bits (271), Expect = 1e-23
Identities = 68/233 (29%), Positives = 115/233 (49%), Gaps = 19/233 (8%)
Query: 56 RNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDRE-KERERQTDRERD 114
R+R + RER+R K E R R R +E RH +D+ ++ + E ++E +D+ R+
Sbjct: 42 RSRSRSRERKR-KSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRE 100
Query: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERE-RQRDAEKERERQTDRERQRQTER 173
R E ++R + ER+ RGR RER R R E+++ R RER++
Sbjct: 101 RLNSSENG--EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKS--- 155
Query: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
R + RER+K+R RER+R+ +++ RH R R R R R +RK++ ++ R
Sbjct: 156 -RSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR--SRSRDRKKRIEKPRR 212
Query: 234 RQRKTERE--------REKQAERERASERETERDKERERERDRDRDRDRRQKE 278
R R R + + A R ER K+ + +R+++ ++Q+E
Sbjct: 213 FSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
Score = 94.7 bits (234), Expect = 2e-19
Identities = 63/240 (26%), Positives = 116/240 (48%), Gaps = 26/240 (10%)
Query: 26 FSRRRPGSQESPRRR-GLGQAHKDAD-GDDRERNRQKERERRREKRQTERETDRKRERRR 83
+SR R S+E R+ G+ H+ + R+ K++ ++ K + + + ++ R
Sbjct: 40 YSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGR 99
Query: 84 EK--------DRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135
E+ DRH++++R R R + R R+ R R R +ER + + R RE ++
Sbjct: 100 ERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE---RRHRSRSRERKKSRSRSRERKKSR 156
Query: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195
R R+R+ R RER+R + R R R R R R+R + R R ++R++R E+ R+
Sbjct: 157 SRSRERKKSRSRSRERKR---RIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRF 213
Query: 196 EKE-NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ-AERERASE 253
+ ++T RGR T + + R +R +K + +REK+ E+++ E
Sbjct: 214 SRSLSRTPSPPPFRGR--------NTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQE 265
Score = 61.6 bits (148), Expect = 2e-09
Identities = 48/195 (24%), Positives = 79/195 (40%), Gaps = 8/195 (4%)
Query: 332 ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391
+TERD + R + ++ + R + R R R RER R+S E +
Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH--- 61
Query: 392 RDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTD 451
R R R KE R KD+ + K+ + E+ + E ++GRER DR ++ +
Sbjct: 62 RSRSRSKEGRRHESKDK-----SSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKE 116
Query: 452 RQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAK 511
R++ R R S +RS + +R + +S + K + +R +
Sbjct: 117 RKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRI 176
Query: 512 ASRGRVAGRRRWEPR 526
SR R R R R
Sbjct: 177 RSRSRSRSRHRHRTR 191
>gi|155030242 WD repeat domain 60 [Homo sapiens]
Length = 1066
Score = 126 bits (317), Expect = 5e-29
Identities = 118/439 (26%), Positives = 204/439 (46%), Gaps = 48/439 (10%)
Query: 59 QKERERRREKRQTERETD---RKRERRREKDRH-RKRDRHRERQRDREKER-ERQTDRER 113
++ER+ R +K + E E D K R R+ D+ R RDR E +E R ER DR+R
Sbjct: 31 KEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQR 90
Query: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ--RQT 171
+R+R+ ++R+KE+ +E RE E+ R D RE+E+ R A KE RQT Q
Sbjct: 91 ERRRDA-KDREKEKLKEKHREAEKSHSRGKD--REKEKDRRARKEELRQTVAHHNLLGQE 147
Query: 172 ERNRQ-KEREREKNRQERRERERQREKENKTEDRHSERGRERERERE------------- 217
R+RQ ER K R + R +++++++ D ER R RER+ +
Sbjct: 148 TRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRER-RYRERKLQYGDSKDNPLKYWL 206
Query: 218 TETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQK 277
+ E ER+ + RE DR K REK + RE+ + E+ ++ +R +++R K
Sbjct: 207 YKEEGERRHRKPREPDRDNK---HREKSSTREKREKYSKEKSNSFS-DKGEERHKEKRHK 262
Query: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ---RETE 334
E D + Q +R ++ + R+RE + RNR +R+ + + R
Sbjct: 263 EGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHG 322
Query: 335 RDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSA-----------R 383
+D++ R+ + + + + +++ G E + E+E E + E R A
Sbjct: 323 KDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKE-ETDLENARADAYTASCEDDFEDY 381
Query: 384 EREERERDRDRDRQKERERQTEKDRD---GQRETEKQREREKDRESERGRERGREREKQK 440
E + D D D EK + Q++ ++ +R + E+ER E + +++
Sbjct: 382 EDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGELSLKLFQKR 441
Query: 441 GR-ERDRERQTDRQAGRQR 458
GR E ++E +TD + R
Sbjct: 442 GRTEFEKEPRTDTNSSPSR 460
Score = 121 bits (304), Expect = 2e-27
Identities = 102/388 (26%), Positives = 181/388 (46%), Gaps = 43/388 (11%)
Query: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDR-HRERQRDREKERERQTDRE-RDRQRE 118
E +RR K T + D ++ + K +R HRE++ +E E + +E R R +
Sbjct: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
Query: 119 KE-RNRQKERERETEREGERGRDRQTDGQRERERQRDA-EKERERQTDRERQRQTERNRQ 176
++ R+R + E T +E RG + D R+RER+RDA ++E+E+ ++ R+ + +R
Sbjct: 62 QDARSRDRVAEVHTAKESPRG---ERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRG 118
Query: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
K+RE+EK+R+ R+E RQ T H+ G+E R+R+ ERK R
Sbjct: 119 KDREKEKDRRARKEELRQ------TVAHHNLLGQE-TRDRQLLERAERK-------GRSV 164
Query: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE 296
R EK + ER E R +ER+ + +D + + + +R+ ++ E DR+
Sbjct: 165 SKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRD 224
Query: 297 TERKRE----RQRERERERERNRKRERERERERERERQRETERDREKER---ERKRKRQT 349
+ + + +RE+ + + N ++ ER +E+ + D E+ + +RK K
Sbjct: 225 NKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAK 284
Query: 350 EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK--- 406
+ R+R Q G R R +RD S++ E R+ +D+ R+ E+
Sbjct: 285 DEPRKRESQNGE------HRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSS 338
Query: 407 ------DRDGQRETEKQREREKDRESER 428
R G ET + + E D E+ R
Sbjct: 339 VWWKLDQRPGGEETVEIEKEETDLENAR 366
Score = 116 bits (290), Expect = 7e-26
Identities = 79/303 (26%), Positives = 145/303 (47%), Gaps = 14/303 (4%)
Query: 170 QTERNRQKEREREKNRQERRERERQREKENKTEDRHSE-RGRERERERETETETER-KRQ 227
Q+ ++++ + REK ++ E + KE + D + R R+R E T E+ R +R
Sbjct: 26 QSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERD 85
Query: 228 TDRERDRQRKT-EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
DR+R+R+R +RE+EK E+ R +E+ R K+RE+E+DR R R+++ R+
Sbjct: 86 RDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDR---RARKEELRQTVAHHN 142
Query: 287 RQRRTERDRETERKRERQR---ERERERERNRKRERERERERERERQRETERDREKERER 343
+ RDR+ + ER+ + R E++ ER E R R+R+ + K+
Sbjct: 143 LLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPL 202
Query: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403
K E R+R+ R RE+ RE+ + ++E+ D+ +R KE+
Sbjct: 203 KYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEK--- 259
Query: 404 TEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
+ ++G +++ + DR+ + ++ R+RE Q G R+R + R + L
Sbjct: 260 --RHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENL 317
Query: 464 YVN 466
N
Sbjct: 318 VRN 320
Score = 107 bits (268), Expect = 2e-23
Identities = 106/454 (23%), Positives = 195/454 (42%), Gaps = 41/454 (9%)
Query: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
R R Q++ R + + H + ER+R ++RERRR+ + +RE ++ +E+ RE ++
Sbjct: 56 RCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAK--DREKEKLKEKHREAEK 113
Query: 88 HRKRDRHRERQRDR--EKERERQT--------DRERDRQ-----REKERNRQKERERETE 132
R + RE+++DR KE RQT RDRQ K R+ K R E +
Sbjct: 114 SHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKD 173
Query: 133 REGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ-KEREREKNRQERRER 191
+ ERG + + RER+ Q K+ + ++ R+R+ +E +R+ +E+
Sbjct: 174 EDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSST 233
Query: 192 ERQREKENKTE-DRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERER 250
+REK +K + + S++G ER +E+ R ++ D + ++ +R++++ ++
Sbjct: 234 REKREKYSKEKSNSFSDKGEERHKEK-------RHKEGFHFDDERHQSNVDRKEKSAKDE 286
Query: 251 ASERETERDKERERERDRDRDRDRRQ------KERERQTDRKRQRRTERDRETERKRERQ 304
+RE++ + R R RD Q + + D +R+ E K + Q
Sbjct: 287 PRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLD-Q 345
Query: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR 364
R E K E + E R E D E + + D N RE
Sbjct: 346 RPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKL 405
Query: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREK-- 422
+ +++E + +++ ER + ++R R TE +++ + +T R
Sbjct: 406 EELPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGR-TEFEKEPRTDTNSSPSRASVC 464
Query: 423 ----DRESERGRERGRERE-KQKGRERDRERQTD 451
D S R++ R + KQK R R D
Sbjct: 465 GIFVDFASASHRQKSRTQALKQKMRSTKLLRLID 498
Score = 77.0 bits (188), Expect = 5e-14
Identities = 77/386 (19%), Positives = 155/386 (40%), Gaps = 20/386 (5%)
Query: 25 DFSRRRPGSQESPRRRGLGQAHKDAD-GDDRERNRQKERERRREKRQTERETDRKRERRR 83
D R R + + L + H++A+ R ++R+KE++RR K + R+T
Sbjct: 87 DRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARK-EELRQTVAHHNLLG 145
Query: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD--- 140
++ R R+ ER + R + R +++ D +R E ++ RER+ + +
Sbjct: 146 QETRDRQLLERAER-KGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKY 204
Query: 141 --RQTDGQRERERQRDAEKE-RERQTDRERQRQTERNRQKEREREKNRQERRERERQREK 197
+ +G+R + R+ +++ + R+ R+++ + +++K +ER + +R +E
Sbjct: 205 WLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEG 264
Query: 198 ENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257
+ ++RH +E+ + E R+R+ Q R R ++R+ S + E
Sbjct: 265 FHFDDERHQSNVDRKEKSAKDE---------PRKRESQNGEHRNRGASSKRDGTSSQHAE 315
Query: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
+ R +D+D R +E + QR + K E E R
Sbjct: 316 -NLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASC 374
Query: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRR-QAERERERERE 376
E + E + + + D R++ E+ + ++ R AE ER E
Sbjct: 375 EDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGELS 434
Query: 377 RDRQSAREREERERDRDRDRQKERER 402
R R E E++ D R
Sbjct: 435 LKLFQKRGRTEFEKEPRTDTNSSPSR 460
Score = 43.5 bits (101), Expect = 6e-04
Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 13/117 (11%)
Query: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
Q+G + RE++ +E + +E R RD D+D + +DR + T K+
Sbjct: 26 QSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARS-------RDRVAEVHTAKE 78
Query: 418 REREKDRESERGRERGREREKQ-KGRERDRERQTDRQAGRQRKRSTLYVNPPPRTAR 473
R ER R+R RER + K RE+++ ++ R+A + R R AR
Sbjct: 79 SPR-----GERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRAR 130
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,920,031
Number of Sequences: 37866
Number of extensions: 1568402
Number of successful extensions: 179366
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1646
Number of HSP's successfully gapped in prelim test: 977
Number of HSP's that attempted gapping in prelim test: 16185
Number of HSP's gapped (non-prelim): 44613
length of query: 600
length of database: 18,247,518
effective HSP length: 108
effective length of query: 492
effective length of database: 14,157,990
effective search space: 6965731080
effective search space used: 6965731080
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.